The Immunity in Health & Disease cluster consists of a vibrant and collaborative group of researchers who have a shared passion for children and immunology. The investigators have a wide range of expertise in microbiology, infectious diseases, rheumatology, hematology, transplantation, oncology, dermatology and vaccination. 

The cluster’s investigators work to discover and explain the cellular and molecular interactions underlying normal versus abnormal responses of the immune system, to discover new cures and therapies for malfunctioning immune responses, and to prevent the spread of infectious diseases.

Ariane Alimenti

Research area:
  • Infectious diseases
  • Pediatric HIV
  • HPV vaccine evaluation in HIV-positive girls and women

Ghada Al-Rawahi

Research area: 
  • Infectious diseases (bacteria & fungus)
  • C. difficile infection in children
  • Candidemia in children
  • Fungal infection in immunocompromised hosts

Julie A. Bettinger

Research area: 
  • Vaccine preventable diseases: meningococcal, pneumococcal, influenza, rotavirus
  • Vaccine safety
  • Surveillance 
  • Immunization knowledge, attitudes and beliefs 
  • Population health
  • Infectious disease epidemiology

David A. Cabral

Research area: 
  • Rheumatology
  • Pediatric vasculitis
  • Systemic lupus erythematosus
  • Pediatric osteoporosis

Edmond S. Chan

Research area: 
  • Food allergies
  • Asthma

Mark Chilvers

Research area: 
  • Cilia
  • Cystic Fibrosis
  • Non-CF Bronchiectasis
  • Pediatric Respirology
  • Clinical Trials

Eva Cho

Research area: 
  • Pediatrics
  • Cystic Fibrosis
  • Medications
  • Pharmacy
  • Adherence

Jean-Paul Collet

Research area: 
  • Evidence-based medicine
  • Clinical research methodology
  • Evaluation
  • Integrative medicine
  • Complementary and alternative medicine

Simon R. Dobson

Research area: 
  • Infections
  • Inflammatory diseases
  • Immunization

Jan P. Dutz

Research area: 
  • The skin immune system and how immune cells called T cells are activated in the skin
  • The process of T cell activation, or priming, in autoimmune disease

Soren Gantt

Research area: 
  • Virology
  • Herpesvirus infections
  • Kaposi sarcoma
  • Epstein-Barr virus
  • Cytomegalovirus
  • HIV
  • Cancer
  • Immune response

Anna Gravelle

Research area: 
  • Cystic Fibrosis
  • Adolescent transition

Jaime Guzman

Research area: 
  • Allergy
  • Clinical epidemiology of childhood rheumatic diseases

M. Rubayet Hasan

Research area: 
  • Virology and infectious disease
  • Laboratory methods for identifying bacteria and viruses

Kristin M. Houghton

Research area: 
  • Rheumatology
  • Exercise in children with chronic illness 
  • Exercise rehabilitation in children with chronic rheumatic diseases

David Israel

Research area: 
  • Gastroenterology
  • Inflammatory bowel disease

Kevan Jacobson

Research area:
  • Gastroenterology
  • Pediatrics
  • Inflammatory bowel disease (IBD)
  • Animal models of IBD
  • Neuro-immune interactions
  • Diet and intestinal inflammation

Anne Junker

Research area: 
  • Primary immune deficiency disorders

Tobias Kollmann

Research area: 
  • Immunology and immunological diseases
  • Developmental immunology/neonatal immunology
  • Infectious disease
  • Vaccines

Pascal M. Lavoie

Research area: 
  • Neonatal Immunity
  • Infection/Inflammation
  • Inheritance/Genetics of Neonatal Morbidities
  • Neonatal Chronic Lung Disease

Megan K. Levings

Research area:
  • T Regulatory Cells 
  • Peripheral Tolerance

Maggie McIlwaine

Research area: 
  • Efficacy of airway clearance techniques in the treatment of Cystic Fibrosis


Research area: 
  • Autoimmunity
  • Diabetes

Millan S. Patel

Research area: 
  • Infections as a cause of preterm birth or birth defects
  • Genetic studies of bone disorders
  • Genetic studies of eye diseases

John Priatel

 Research area: 
  • Content coming soon!

Colin Ross

Research area: 
  • Pharmacogenomics of adverse drug reactions
  • Medical Genetics
  • Gene therapy
  • Clinical and pediatric pharmacology
  • Pharmacoepidemiology
  • Pharmacoeconomics/outcomes
  • Drug safety
  • Biochemical pharmacology
  • Childhood cancer
  • Late effects of childhood survivors of cancer
  • Clinical trials in pediatric oncology
  • Genetic testing
  • Lipoprotein Lipase Deficiency

Laura Suave

Research area:
  • Vaccine-preventable diseases surveillance
  • HIV surveillance
  • Vaccine Evaluation Center

David W. Scheifele

Research area: 
  • Vaccine Evaluation Center
  • Vaccines and immunization
  • Epidemiology of vaccine-preventable infections
  • Vaccine safety
  • Immunization program evaluation

Richard A. Schreiber

Research area:
  • Pediatric liver disease
  • Pediatric liver transplantation
  • Biliary atresia
  • Viral hepatitis
  • Immune mediated bile duct disease

Kirk R. Schultz

Research area: 
  • Immune system
  • Childhood leukemia
  • Blood and marrow transplantation
  • Tumour immunology 

Michael D. Seear

Research area: 
  • Childhood respiratory diseases
  • International health - mainly respiratory diseases of children in low-resource areas but also research into pharmaceutical quality in developing countries.
  • Clinical pediatric respiratory medicine.
  • Home ventilation - epidemiology and clinical management of children who need ventilator support in their homes.

Laura M. Sly

Research area: 
  • Macrophages
  • Intestinal immunity
  • Inflammatory bowel disease
  • Innate immune response

David P. Speert

Research area: 
  • Infectious diseases
  • Innate immunity
  • Cystic fibrosis

Lori Tucker

Research area: 
  • Rheumatology
  • Predicting and improving outcomes for children and youth with chronic rheumatic diseases such as juvenile arthritis and systemic lupus erythematosus
  • Understanding the impact of chronic disease on children and families, using standardized questionnarires-methodology and correlation with clinical outcomes

Stuart Turvey

Research area: 
  • Innate immunity
  • Host defense
  • Primary immunodeficiency diseases (PIDs)
  • Role of Toll-like receptors in human disease
  • Airway inflammation in cystic fibrosis
  • Asthma and allergic disease

Bruce A. Vallance

Research area: 
  • Enteric bacterial pathogens
  • Innate immunity
  • Intestinal inflammation
  • Host defense
  • Inflammatory bowel disease

Peter van den Elzen

Research area: 
  • Autoimmunity
  • Lipid antigens
  • Immune monitoring

Peter von Dadelszen

Research area: 
  • Pre-eclampsia / Hypertension in pregnancy / IUGR
  • Th2 pregnancy immunology / Infection & atherosis
  • Clinical epidemiology / Health services research
  • Flow cytometry / Cell & molecular biology / Translational research

Connie Yang

Research area: 
  • Asthma
  • Cystic Fibrosis