• Brown, Carolyn

    Titles
    Affiliate Investigator, BC Children's Hospital
    Professor, Department of Medical Genetics, University of British Columbia
    Degrees / Designations
    PhD
    Primary Area of Research
    Healthy Starts
    Secondary Area(s) of Research
    Phone
    604-822-0908
    Fax
    604-822-5348
    Lab Phone
    604-822-1239
    Mailing Address
    Molecular Epigenetics Group
    Life Sciences Centre
    2350 Health Sciences Mall
    Vancouver, BC V6T 1Z3
    Affiliate Websites
    Research Areas
    • Human X chromosome inactivation
    Summary

    X chromosome inactivation occurs early during mammalian development to transcriptionally silence one of the pair of X chromosomes in females, thereby achieving dosage equivalence with males who have a single X chromosome and the sex-determining Y chromosome.  Research in the lab is directed towards understanding both the mechanisms involved in the inactivation process and the clinical implications of X chromosome inactivation in females.

    Current Projects
    Selected Publications
    Grants
    Honours & Awards
    Research Group Members