• Vila-Rodriguez, Fidel

    Titles

    Affiliate Investigator, BC Children's Hospital
    Assistant Professor, Department of Psychiatry, Faculty of Medicine, University of British Columbia

    Degrees / Designations

    M.Sc., MD

    Primary Area of Research
    Brain, Behaviour & Development
    Secondary Area(s) of Research
    Phone
    604-875-2000 ext. 4732; 604-827-0175
    Fax
    Lab Phone
    Mailing Address

    Detwiller Pavilion
    University of British Columbia
    2255 Wesbrook Mall
    Vancouver, BC V6T 2A1

    Affiliate Websites
    Research Areas
    • Non-Invasive neurostimulation therapies 
    • Psychotic disorders 
    • Depression
    • Brain imaging
    • Catatonia
    • Neurostimulation therapies
    • Child and Adolescent psychosis and depression
    Summary

    As a Clinician-Scientist, I have a strong interest in conducting translational research that bridges our understanding on the neurobiology of psychiatric illnesses with the clinical applications of this knowledge. I am particularly interested in applying this strategy to severe psychiatric disorders such as refractory psychosis and treatment resistant depression. My clinical practice is actively focused in those most severely afflicted by such conditions, and my research interests are directed at finding novel therapeutic interventions within Non-Invasive Neurostimulation Therapies (NINETs) that can help mitigate the suffering of those with severe and refractory forms of psychosis and depression, including pediatric populations. I strongly believe that understanding NINETs’ mechanism(s) of action is a critical step towards translating this knowledge to clinical practice. More important, translating that knowledge to clinical practice will have a direct, immediate, and positive impact on the life’s of those who struggle and suffer the most devastating forms of mental illness and their families.

    Current Projects
    Selected Publications

    Tse L, Scarapicchia V, Barr AM and Vila-Rodriguez F. Neuroleptic malignant syndrome: a review from a clinically oriented perspective. (Current Neuropharmacology, In press).

    Schultz K, Tham J, Northcott C,  Chan P, Vila-Rodriguez F. Occurrence of Postictal α/β Activity During Maintenance Course of Electroconvulsive Therapy. J  ECT. 2015 Mar 10. [Epub ahead of print] PMID: 25764162.

    Lang DJ, Yip E, MacKay AL, Thornton AE, Vila-Rodriguez F, MacEwan GW, Kopala LC, Smith GN, Laule C, MacRae CB and Honer. WG. 48 Echo T2 Myelin Imaging of White Matter in First-Episode Schizophrenia: Evidence for Aberrant Myelination. Neuroimage: Clinical 2014 Oct 15;6:408-14. PMID: 25379454

    Honer WG, Jons A, Thornton AE, Barr AM,  Procyshyn RM, Vila-Rodriguez, F. Response Trajectories to Clozapine in a Secondary Analysis of Pivotal Trials Support Using Treatment Response to Subtype Schizophrenia. The Canadian Journal of Psychiatry, Vol 60, Supplement 2, March 2015. PMID: 25886676

    Gicas K, Vila-Rodriguez F, Paquet K, Barr A, Procyshyn R, Lang D, Smith G, Baitz H, Giesbrecht C, Montaner J, Krajden M, Krauz M, MacEwan G, Panenka W, Honer W, Thornton A. Neurocognitive Profiles of Marginally Housed Persons with Comorbid Substance Dependence, Viral Infection, and Psychiatric Illness. Journal of Clinical and Experimental Neuropsychology 2014 Nov 7:1-14. PMID: 25380059

    Vila-Rodriguez F, Northcott C, Tham J. Single Occurrence of Intraictal Cessation during index course electroconvulsive therapy. J ECT. 2014 Jul 28. [Epub ahead of print]. PMID: 25072128

    Vila-Rodriguez F, McGirr, Tham, J, Hadjipavlou G,  Honey C.  Electroconvulsive therapy in patients with deep brain stimulators. J ECT 2014 Sep;30(3):e16-8. PubMed PMID: 24625701

    Jones A, Vila-Rodriguez F, Panenka, W, Leonova  O, Strelhau V, Lang DJ, Thornton AE, Wong H, Barr AM, Procyshyn RP, Siddu JJ, Smith GN, Buchanan T, Krajden M, Krausz M, Montaner JS, MacEwan GW, Nutt  DJ, and Honer WG. Drug related harm is associated with mortality, poor physical, psychological, and social health in a community sample living in marginal housing. PLOS One 2013 Nov 6;8(11):e79754. PMID: 24223192

    Vila-Rodriguez F, Downar JH, Blumberger DM. Repetitive Transcranial Magnetic Stimulation In Depression: A Changing Landscape. Psychiatric Times, June 19th, 2013 at http://www.psychiatrictimes.com/depression/repetitive-transcranial-magnetic-stimulation-depression-changing-landscape.

    Vila-Rodriguez F, Tsang P, Barr A. Chronic benign neutropenia/agranulocytosis associated to non-clozapine neuroleptics. Am J Psychiatry. 2013 Oct 1;170(10):1213-1214. PMID: 24084822

    Vila-Rodriguez F, Panenka, W, Lang DJ, Thornton AE, Vertinsky T, Wong H, Barr AM, Procyshyn RP, Sidhu JJ, Smith GN, Buchanan T, Krajden M, Krausz M, Montaner JS, MacEwan GW, and Honer WG. The Hotel study: multimorbid drug dependence, neuropsychiatric illness, HIV and HCV infection in a community sample living in marginal housing. Am J Psychiatry. 2013; 170(12): 1412-1422 9. PMID: 23929175

    Sarró S, Pomarol-Clotet E, Canales-Rodríguez E, Salvador R, Gomar J, Landín-Romero R, Vila-Rodríguez F, Blanch J and McKenna PJ. Structural brain changes associated with tardive dyskinesia in schizophrenia. Br J Psychiatry. 2013 Jul; 203(1): 51-7. PMID: 23222039

    Vila-Rodriguez F, Tham J. The relevance of EEG artifact identification: a case of ‘delta-wave blinking’ due to tardive disknesia. J ECT. 2013 Mar;29(1):13-4. PMID: 23422518

    Lee, Honer WG, MacKay AL, Su W, Thornton AE, Smith GN,  MacEwan GW,  Lapointe JS,  Vertinsky AT, Vila-Rodriguez F,  Kopala LC, and Lang DJ. A DTI study of frontal white matter tract abnormalities in a cohort of early psychosis patients. Schizophr Res. 2012 Oct;141(1):29-34.

    Vila-Rodriguez, F, Honer WG, Innis SM, Wellington CL, Beasley CL. ApoE and cholesterol in schizophrenia and bipolar disorder: comparison of grey and white matter and relationship with APOE genotype. J Psychiatry Neurosci. 2011 Jan; 36(1): 47-55. PMID: 20964956

    Salvador R, Sarró S, Gomar J, Ortiz-Gil J, Vila F,  Sarró S, Gomar J, Capdevila A, Bullmore E, McKenna PJ, Pomarol-Clotet E. Overall brain connectivity maps show cortico-subcortical abnormalities in schizophrenia. Human Brain Mapping. 2010 Dec; 31(12): 2003-14. PMID: 20225222

    Pomarol- Clotet E, Salvador R, Sarró S, Gomar J, Ortiz-Gil J, Vila F, Capdevila A, Bullmore E, McKenna PJ. Medial prefrontal cortex pathology in schizophrenia as revealed by convergent findings from multimodal imaging, Mol Psychiatry. 2010 Aug;15(8):823-30. PMID: 20065955

    Vila-Rodriguez F and MacEwan GW. Delusional parasitosis facilitated by web-based dissemination. Am J Psychiatry. 2008 Dec; 165(12):1612. PMID: 19047336

    Vila-Rodriguez F, French L, Barakauskas V, Mead CL, Khorram B. Thalamic shape: a possible endophenotype. J Neurosci. 2008 Apr 2; 28(14):3533-4. PMID: 18385311

    Pomarol-Clotet E, Salvador R, Sarró S, Gomar J, Vila F, Martínez A, Guerrero A, Ortiz-Gil J, Sans-Sansa B, Capdevila A, Cebamanos JM, McKenna PJ. Failure to deactivate in the prefrontal cortex in schizophrenia: dysfunction of the default mode network? Psychol Med. 2008 May 29:1-9. PMID: 18507885

    Salvador R, Martínez A, Pomarol-Clotet E, Gomar J, Vila F, Sarró S, Capdevila A, Bullmore E. A simple view of the brain through a frequency-specific functional connectivity measure. Neuroimage. 2008 Jan 1; 39(1):279-89. PMID: 17919927

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