• Sauvé, Laura

    Titles

    Investigator, BC Children's Hospital
    Clinical Assistant Professor, Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, University of British Columbia

    Degrees / Designations

    MD, MPH

    Primary Area of Research
    Healthy Starts
    Secondary Area(s) of Research
    Phone
    604-875-3465
    Fax
    Lab Phone
    Mailing Address

    BC Children's Hospital
    Room 2D5
    4480 Oak Street
    Vancouver, BC, V6H 3N4 

    Affiliate Websites
    Research Areas
    • Vaccine-preventable diseases surveillance
    • HIV surveillance
    Summary

    Dr. Laura Sauvé is a Clinical Assistant Professor and a pediatric infectious disease specialist who has a special interest in Pediatric HIV/AIDS.  

    Her main research interests include public health surveillance especially with respect to vaccinology, vaccine preventable disease, global child health and pediatric HIV/AIDS.  

    She joined the Vaccine Evaluation Center in 2007 as the BC site investigator for the Immunization Monitoring Program, Active (IMPAct), a national surveillance system for vaccine preventable diseases and vaccine adverse events in 12 pediatric tertiary care centers across Canada. 

    She is also the co-primary investigator of the Canadian Perinatal HIV Surveillance Program, which studies vertical transmission of HIV across Canada. As Pediatrics Residency Program Director, she is also involved in a number of medical education research initiatives.

    Current Projects

    Immunization Monitoring Program, Active

    Dr. Sauvé is the BC site investigator for this project which has ongoing surveillance for vaccine preventable diseases and adverse events following immunization; there are 12 sites across the country. She sits on the AEFI and Haemophilous Influenzae working groups. Nurse monitors at each site do active surveillance for the target conditions, finding all hospitalized cases of those target conditions using a variety of methods.  Data is entered into the IMPACT databases which are coordinated through the Vaccine Evaluation Center's IMPACT data center (led by CFRI investigators Dr. David Scheifele and Dr. Julie Bettinger). Summarized surveillance data is provided to the Public Health Agency of Canada and published in peer-reviewed publications.

    Flocked swab evaluation

    In this study which is in the final manuscript stages, Dr Sauvé and her co-investigators prospectively evaluated two methods of acquiring samples for respiratory virus testing, comparing the BC Children's Hospital standard of nasopharyngeal wash, to a newer technology: flocked nasopharyngeal swabs.

    Canadian Perinatal HIV Surveillance Program (WHRI)

    Dr.  Sauvé recently took over as co-chair of the CPHSP, which as done active surveillance for vertical transmission of HIV in 22 sites across Canada since 1990. It is funded by the Public Health Agency of Canada. This surveillance program prospectively collects data on all births to HIV infected women in the 22 participating sites, as well as all vertically HIV infected children in Canada. It provides important epidemiologic data on vertical transmission of HIV in Canada. Data is presented annually at HIV meetings and in 2012, there was a major article in AIDS (completed prior to when Dr Sauvé joined the team).

    Scholarship of education

    Dr. Sauvé has led or participated in several medical education studies, particularly in the area of global health education for pediatrics residents. She was part of a team which developed, systematically evaluated and rolled out educational modules on important global health topics for pediatrics residents across the country. She is currently also working on studies examining optimal pre-departure training for residents doing electives outside of Canada.

    Selected Publications

    Souarès Y, Sauve L. Harmonization of regional health data requirements in the South Pacific. Clin Perform Qual Health Care. 1997 Apr-Jun;5(2):99-103. (CA)

    Brophy J, Sauvé L. Clinician's Corner Case 2: Fever in a new immigrant. Pediatrics and Child Health 10(5): 283-285, 2005  (CA)

    Sauvé LJ, Scheifele D. Do childhood vaccines cause thrombocytopenia? Paediatrics and Child Health;14(1):31, 2009. (FA)

    Morris SK, Richardson SE, Sauvé L, Ford-Jones EL, Jamieson F.  Increasing Fluoroquinolone Resistance in Salmonella typhi in Ontario, 2002-2007.  American Journal of Tropical Medicine and Hygiene; 80(6):1012-3. June 2009. (CA)

    Sauvé LJ, Bettinger J, Scheifele, D, Halperin S, Vaudry W, Law B , for Members of the Canadian Immunization Monitoring Program, Active (IMPACT).  Post-vaccination thrombocytopenia in Canada. Pediatric Infectious Diseases Journal. Pediatric Infectious Diseases Journal. 2010 Jun;29(6):559-61. (FA)

    Bettinger J, Sauve LJ, Scheifele DW,  Moore D, Vaudry W, Tran D, Halperin SA, Pelletier L, for Members of the Canadian Immunization Monitoring Program, Active (IMPACT).  Pandemic Influenza in Canadian Children: A Summary of Hospitalized Pediatric Cases. Vaccine. 2010 Apr 19;28(18):3180-4. Epub 2010 Feb 26  (CA)

    Al-Dabbagh M, Lapphra K, McGloin R, Inrig K, Schaaf HS, Marais BJ, Sauve L, Kitai I, Kollmann TR. Drug-resistant tuberculosis: pediatric guidelines. Pediatr Infect Dis J. 2011 Jun;30(6):501-5.  (CA)

    Rubinstein E, Predy G, Sauvé L, Hammond GW, Aoki F, Sikora C, Li Y, Law B, Halperin S, Scheifele D. The responses of Aboriginal Canadians to adjuvanted pandemic (H1N1) 2009 influenza vaccine. CMAJ. 2011 Sep 20;183(13):E1033-7. Epub 2011 Jul 25. (CA) 

    Grants
    • IMPACT / CPS - Approximately $57,000 per year for BC Site (ongoing)
    • CPHSP - $39,000 per year (ongoing)
    • BC Children's Hospital Foundation Telethon Fund (flocked swab study) $24,000
    • Copan Diagnostics (flocked swab study) $20,000
    Honours & Awards
    Research Group Members
    • IMPACT : Karen Kroeker (Lead IMPACT Nurse Monitor), Kathy Leung (IMPACT Nurse Monitor), Debbie Heayn (Lead Data Scrutineer), Jan Van Bynder (Data Scrutineer)
    • CPHSP: Evelyn Maan (Research Manager, Oak Tree Clinic) - WHRI
    • Collaborate with the Vaccine Evaluation Centre