• Leveille, Lise A.

    Titles

    Investigator, BC Children's Hospital
    Clinical Instructor, Pediatric Orthopaedic Surgery, Department of Orthopaedics, University of British Columbia  

    Degrees / Designations

    MD

    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    Phone
    604-875-2627
    Fax
    604-875-2275
    Lab Phone
    Assistant
    Melissa Hart
    Assistant Phone
    604-875-2627
    Mailing Address

    BC Children's Hospital
    Room 1D-70 
    4480 Oak Street,
    Vancouver, BC  V6H 3V4

    Affiliate Websites
    Research Areas
    • Pediatric sports injuries
    • Acute knee injuries
    • Pediatric orthopaedic trauma 
    • Growth modulation 
    • Cerebral palsy 
    • Clinical applications of instrumented gait analysis
    Summary

    Pediatric Sports injuries: As more children and adolescents become active in sports, injuries relating to their involvement have become more common. Patellar instability and anterior cruciate ligament (ACL) injuries are commonly seen in this age group. My research in this area focuses on identifying injuries quickly and helping kids get back to their desired sports and activities.

    Cerebral palsy and gait analysis: Cerebral palsy is a neuromuscular condition that affects gait (walking) and posture. Instrumented gait analysis allows us to accurately document how a child is walking and identify ways in which we can improve their mobility. My research in this area focuses on using instrumented gait analysis to assess the impact of orthopaedic surgical interventions in children with cerebral palsy.  

    Current Projects

    Frequency of Crouch Gait in Spastic Diplegic Patients With and Without History of Tendo Achilles Lengthening: Crouch gait is part of the natural history of gait pattern change over time in children with spastic diplegia. This has been attributed to changes in strength to mass ratio with the adolescent growth spurt, progressive lever arm dysfunction, and iatrogenic weakening of the soleus with tendo Achilles lengthening. The relative importance of each of these factors is uncertain. The purpose of this project is to determine the impact of orthopaedic surgical intervention on progression to crouch gait in children with spastic diplegia. 

    Rebound Deformity After Growth Modulation: Growth modulation uses a small surgical implant to tether one side of the growth plate allowing us to harness the power of the growth for deformity correction.  As popularity for this procedure has grown, it has been used in progressively younger patients. This results in deformity correction being achieved prior to skeletal maturity, requiring removal of the surgical impact to prevent over correction.  Once the tether has been removed, growth resumes and there is potential for rebound deformity. Accurate timing of initial intervention with growth modulation and timing of implant removal is unclear. The purpose of this research is to determine the frequency and magnitude of rebound deformity after growth modulation.  

    Selected Publications

    Leveille L, Ozan R, Johnston C. Rebound deformity after growth modulation in patients with coronal plane angular deformities about the knee: who gets it and how much? Journal of Pediatric Orthopaedics. In press.  

    Bogdan Y, Tornetta P 3rd, Einhorn TA, Guy P, Leveille L, Robinson J, Bosse MJ, Haines N, Horwitz D, Jones C, Schemitsch E, Sagi C, Thomas B, Stahl D, Ricci W, Brady M, Sanders D, Kain M, Higgins TF, Collinge C, Kottmeier S, Friess D. Healing time and complications in Operatively treated atypical femur fractures associated with bisphosphonate use: A multicenter retrospective cohort. Journal of Orthopaedic Trauma. 2016;30(4):177-81. 

    Hesketh K, Leveille L, Mulpuri K. The frequency of AVN following reconstructive hip surgery in children with cerebral palsy: a systematic review. Journal of Pediatric Orthopaedics. 2016;36(2):e17-24.

    Reilly CW, McEwen JA, Leveille LA, Perdios A, Mulpuri K. Minimizing tourniquet pressure in pediatric anterior cruciate ligament reconstructive surgery: a blinded, prospective randomized controlled trial. Journal of Pediatric Orthopaedics. 2009;29:275-280.

    Grants
    Honours & Awards
    Research Group Members