My clinical research interests focus on surgical treatment of congenital anomalies and childhood cancers, with a particular interest in low-income settings. I am starting a clinical trial for gastroschisis patient care in Uganda, in an effort to address extremely high (98%) mortality of children with gastroschisis in this setting. The focus of the trial is to develop and test low-cost interventions designed to increase survival through improved pre-hospital and peri-operative care, as well as testing novel nutritional treatments which may be feasible in a low-income country (LIC). This pilot study may allow development of a multi-center study of surgical treatment congenital anomalies in LICs in Sub-Saharan Africa. The goal is to start this study in 2017.
Currently I am working with a group of pediatric surgeons across the United States as part of the Childhood Cancer Database Research (CCDR) team, investigating adult types of cancers in pediatric patients in an attempt to understand the biology, behavior and best treatment for children and young adults with these tumors. My projects focus on colorectal cancer, carcinoid tumors, and pancreatic cancer in children. I am also interested in studying outcomes from different central venous lines in children with cancer to determine if there is evidence to guide catheter choice and maintenance.
I am particularly interested in surgical disease and treatment in developing countries. My interest focuses both assessing the burden of disease as well as strategies with education and international participation to effect positive change in this arena.