• McDonald, Patrick

    Titles

    Investigator, BC Children's Hospital

    Division Head, Pediatric Neurosurgery, BC Children's Hospital

    Associate Professor, Department of Surgery, University of British Columbia

    Degrees / Designations

    MD, MHSc, FRCSC

    Primary Area of Research
    Brain, Behaviour & Development
    Secondary Area(s) of Research
    Phone
    604-875-2094
    Fax
    604-875-2094
    Lab Phone
    Assistant
    Alexander Cheong
    Assistant Phone
    604-875-2345 ext. 7132
    Mailing Address

    BC Children's Hospital
    Room K3-216
    4480 Oak Street
    Vancouver, BC V6H 3V4

    Affiliate Websites
    Research Areas
    • Hydrocephalus
    • Pediatric Brain tumours
    • Concussion
    • Spina Bifida
    • Surgical innovation
    • Bioethics/Neuroethics
    Summary
    My research focuses on three principal areas:
    • Clinical outcomes and innovation in the treatment of pediatric hydrocephalus: BC Children’s Hospital is one of only two Canadian centres in the Hydrocephalus Clinical Research Network
    • Outcomes, novel therapies and imaging findings in concussion and mild traumatic brain injury: as a researcher in the  Canada North Concussion Network, a Winnipeg-based consortium, we are investigating novel imaging techniques to diagnose and monitor recovery from concussion
    • Bioethics/Neuroethics: I conduct research in various aspects of bioethics as it relates to neurosurgery including conflicts of interest in neurosurgical research,  ethical issues in fetal surgery for spina bifida and the role of ethics education in neurosurgery training
    Current Projects
    • Targeting the CSF microbiota to optimize CSF shunt infection treatment- we are analyzing the spinal fluid in children with shunts used to treat hydrocephalus in order to determine the best way to prevent and manage shunt infections.
    • Novel neuro-imaging assessment of cerebrovascular reactivity and default-mode networks in adolescent sports-related concussion- we are attempting to develop an MRI based test to give an objective measure of recovery following sports related concussion.
    • Conflicts of interest in neurosurgical research- we are determining the scope and disclosure of financial conflicts of interest in published neurosurgical research.
    Selected Publications

    Ellis  MJ, McDonald PJ, Cordingly D, Mansouri B, Ritchie L: Retirement from sport- Considerations following pediatric sports-related concussion: Case illustrations and institutional approach. Neurosurg Focus (2016- accepted for publication) PMID: 27032925

    Russell K, Ritchie L, Vis S, Chu S, Selci E, McDonald PJ, Ellis MJ: Measuring the scientific impact of sports-related concussion research: a citation analysis study. Curr Research: Concussion 2016 (in press)

    Ellis MJ, Ritchie L, Selci E, Chu S, McDonald PJ, Russell K: Googling concussion care: a critical appraisal of online concussion healthcare providers and practices in Canada. Clin J Sport Med Feb 26,2016 (epub ahead of print) PMID: 26867204

    Hansen G, McDonald PJ, Martin D, Vallance JK: Pre-Trauma Centre management of intracranial pressure in severe pediatric TBI. Pediatric Emergency Care 2016 (accepted for publication)

    McDonald PJ: Ventriculoperitoneal shunt failure from spontaneous knotting of the peritoneal catheter. CMAJ (epub ahead of print, Dec 22, 2015) PMID: 26696620

    Steinbok P, Gopalakrishnan CV, Hengel AR, Vitali AM, McDonald PJ, Hukin J, et. al: Pediatric thalamic tumors in the MRI era: a Canadian perspective. Childs Nerv Syst 2015 (epub ahead of print) PMID: 26597682

    Zeiler FA, Silvaggio J, Iancu D, McDonald PJ: Secondary vein of Galen malformation treated with combined endovascular and endoscopic approach. Interdisciplinary Neurosurg 2015 2:164-167.

    Zeiler FA, Janik MK, McDonald PJ, Kaufmann AM, Fewer D, Butler J, Schroeder G, West M: Gamma Knife radiosurgery for pediatric arteriovenous malformations: a Canadian experience. Can J Neurol Sci 43(1):82-6, 2016. PMID: 26306863

    Ellis MJ, Leiter J, Hall T, McDonald PJ, Sawyer S, Silver N, Bunge M, Essig M: Neuroimaging findings in sports-related concussion: clinical article. J Neurosurg Pediatrics 16:241-247, 2015. PMID: 26031620

    Haji F, Clarke DB, Matte M, Brandman DM, Brien S, deRibaupierre S, O’Kelly C, Christie S, Wallace MC, McDonald PJ, Kulkarni AV, Walling S, Macleod A: Teaching for the transition: the Canadian neurosurgery “Rookie Camp” for PGY-1 trainees. Can J Neurol Sci 42(1):25-33, 2015. PMID: 25573052

    Grants

    Targeting the CSF microbiota to optimize CSF shunt infection treatment
    Source: National Institutes of Health (NINDS)- USA
    Role: Local Principal Investigator

    A randomized controlled trial of anterior versus posterior entry site for cerebrospinal fluid shunt insertion 2015-2018
    Source: Patient-Centered Outcomes Research Institute Grant #CER-1403013857
    Role: Local Principal Investigator

    Conflicts of interest in neurosurgical research: Comparing voluntary disclosure with company data July 2014- August 2015
    Source: College of Medicine, University of Manitoba BSc Med Program
    Role: Principal Investigator

    Novel neuro-imaging assessment of cerebrovascular reactivity and default-mode networks in adolescent sports-related concussion January 2014- December 2015
    Source: Department of Surgery, University of Manitoba 
    Role: Principal Investigator

    Honours & Awards

    University of Manitoba Outreach Award

    Research Group Members
    • Alexander Cheong
    • Vesna Popovska 
    • Julia Radic
    • Sudheesh Ramachandran