• Wong, Tiffany

    Titles

    Investigator, BC Children's Hospital
    Clinical Assistant Professor, Division of Allergy and Immunology, Department of Pediatrics, University of British Columbia

    Degrees / Designations
    MD, FRCPC
    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    Phone
    604-875-2118
    Fax
    Lab Phone
    Assistant
    Lisa Wilson
    Assistant Phone
    604-875-2118
    Mailing Address
    BC Children's Hospital
    Room 1C31B
    4480 Oak Street
    Vancouver, BC  V6H 3V4
    Affiliate Websites
    Research Areas
    • Drug allergy
    • Food allergy
    Summary

    My areas of research interest lies within the area of pediatric drug allergy. Many patients labelled as allergic to medications are not actually allergic – this has significant impact on medication selection for subsequent illnesses, and leads to less optimal medication being prescribed to the patient at increased costs to the health care system. This is of particular concern in patients with complex medical needs who often require admission to hospital or treatment with medications. I hope that by developing a program aimed at clarifying the nature of reactions and de-labeling allergy, we can optimize medication selection and patient care, both in hospital and in the community.

    I am also involved in projects involving a variety of aspects of food allergy, including optimizing management of allergic reactions by patients/families and describing unusual cases of food allergy in pediatrics.

    Current Projects

    Penicillin de-labelling Study:
    Penicillin allergy is a common drug allergy diagnosis. However, upon assessment by Allergists, many people are not actually allergic. Patients can be erroneously labelled as allergic due to misclassification of a suspected reaction. As a result, many patients will receive alternative antibiotics that are more expensive, potentially less effective, more toxic, and may increase risk of antibiotic resistance. The goal of this study is to develop assessment tools and a program to help pediatric health care providers identify those who are at low risk of penicillin allergy and de-label them. 

    Epinephrine Autoinjector Study: 
    Families in Pediatric Allergy Clinic often report that they are fearful of using an epinephrine autoinjector despite receiving education on indications for use and technique. It is very important that patients and caregivers have the skills, knowledge and confidence to administer the epinephrine autoinjector when indicated. The goal of this study is to assess the impact of self or caregiver-administrated epinephrine in a medically supervised setting on the confidence of patient and/or caregivers for future use of epinephrine autoinjector.

    Selected Publications

    Wong T, Ko HH, Chan E. IgE-Mediated allergy to wheat in a child with celiac disease – a case report. Allergy, Asthma and Clinical Immunology. 2014;10(56)

    Al Ghaithi I, Wright NAM, Breakey VR, Cox K, Warias A, Wong T, O’Connel C, Price V. Combined Autoimmune Cytopenias Presenting in Childhood: A Retrospective Chart Review. Pediatric Blood and Cancer: 2016;63(2): 292-298

    Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DW. Alternating and combined antipyretics for the treatment of fever in children. Cochrane Database of Systematic Reviews, 2013 Oct 30;10:CD009572. doi: 10.1002/14651858.CD009572.pub2

    Wong T, Yeung J, Hildebrand KJ, Junker AK, Turvey SE. Human Primary immunodeficiencies causing defects in innate immunity. Current Opinion in Allergy and Clinical Immunology. 2013 Dec;13(6): 607-13. 

    Grants
    Honours & Awards
    Research Group Members
    • Christopher Mill, Allergy Research Coordinator
    • Hannah Roberts, Clinical Fellow