• Chan, Wee-Shian

    Titles

    Investigator, BC Children's Hospital
    Clinical Associate Professor, University of British Columbia
    Lead, Obstetric Medicine, BC Women's Hospital
    Head, Department of Medicine, BC Women's Hospital

    Degrees / Designations

    MD, MSc, FRCPC, FACP

    Primary Area of Research
    Healthy Starts
    Secondary Area(s) of Research
    Phone
    604-875-3539
    Fax
    Lab Phone
    Assistant
    Alyson McKendrick
    Assistant Phone
    (60) 875-2000, Ext. 6622
    Mailing Address

    BC Children's Hospital
    Room B411, 4500 Oak Street
    Vancouver, BC V6H 3N1

    Research Areas
    Summary
    I work with patients with medical complications in pregnancy, but specifically in the area of Venous Thromboembolism in Pregnancy.
    Current Projects
    Selected Publications
    • Rodger MA, Phillips P, Kahn SR, James AH, Konkle BA; PROSPER Investigators, Chan, WS, Collaborator, “Low-molecular-weight heparin to prevent postpartum venous thromboembolism. A pilot randomised placebo-controlled trial.” Thromb Haemost 2015 Jan;113(1): 216-6. PMID: 25373438

    • Rodger MA, Hague WM, Kingdom J, Kahn SR, Karovitch A, Sermer M, Clement AM, Coat S, Chan WS, Said J, Rey E, Robinson S, Khurana R, Demers C, Kovacs MJ, Solymoss S, Hinshaw K, Dwyer J, Smith G, McDonald S, Newstead-Angel J, McLeod A, Khandelwal M, Silver RM, Le Gal G, Greer IA, Keely E, Rosene-Montella K, Walker M, Wells PS; TIPPS Investigators, “Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial.” Lancet 2014 Nov 8;384(9955): 1673-83 . PMID: 25066248

    • Goodacre S, Nelson-Piercy C, Hunt B, Chan WS, “When should we use diagnostic imaging to investigate for pulmonary embolism in pregnant and postpartum women?” Emerg Med J. 2015 Jan;32(1):78-82. PMID: 25007912

    • Chan WS, Rey E, Kent NE; VTE in Pregnancy Guideline Working Group, Chan WS, Kent NE, Rey E, Corbett T, David M, Douglas MJ, Gibson PS, Magee L, Rodger M, Smith RE, “Venous thromboembolism and antithrombotic therapy in pregnancy.” J Obstet Gynaecol Can. 2014 Jun;36(6):527-53. PMID: 24927193

    • Tanguay JF, Bell AD, Ackman ML, Bauer RD, Cartier R, Chan WS, Douketis J, Roussin A, Schnell G, Verma S, Wong G, Mehta SR; “Focused 2012 update of the Canadian Cardiovascular Society guidelines for the use of antiplatelet therapy.” Can J Cardiol.  2013 Nov;29(11):1334-45 . PMID: 23978596

    • Tanguay JF, Bell AD, Ackman ML, Bauer RD, Cartier R, Chan WS, Douketis J, Roussin A, Schnell G, Verma S, Wong G, Mehta SR, "Focused 2012 Update of the Canadian Cardiovascular Society Guidelines for the Use of Antiplatelet Therapy." Can J Cardiol. 2013 Nov;29(11):1334-45. PMID: 23978596

    • Chan WS, Spencer FA, Lee AY, Chunilal S, Douketis JD, Rodger M, Ginsberg JS, "Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imaging." CMAJ: 185(4). PMID: 23318405

    • Bell AD, Roussin A, Cartier R, Chan WS, Douketis JD, Gupta A, Kraw ME, Lindsay TF, Love MP, Pannu N, Rabasa-Lhoret R, Shuaib A, Teal P, Théroux P, Turpie AG, Welsh RC, Tanguay JF; Canadian Cardiovascular Society, "The use of antiplatelet therapy in the outpatient setting: Canadian Cardiovascular Society guidelines." Can J Cardiol. 27(Suppl A:S1-59). PMID: 21640290

    • Bell AD, Roussin A, Cartier R, Chan WS, Douketis JD, Gupta A, Kraw ME, Lindsay TF, Love MP, Pannu N, Rabasa-Lhoret R, Shuaib A, Teal P, Théroux P, Turpie AG, Welsh RC, Tanguay JF, "The use of antiplatelet therapy in the outpatient setting: Canadian Cardiovascular Society Guidelines Executive Summary." Can J Cardiol. 2(27). PMID: 21459270

    • Chan WS, "Venous thromboembolism in pregnancy." Expert Rev Cardiovasc Ther. Dec; 8(12). PMID: 21108555

    Grants
    • National Institute of Health grant - Project: "Exploring Host Gene Expression during Post-Exertional Symptom Flare in ME/CFS: An experimental approach." Co-investigator. Total Funding: $271,828 (2015 - 2017)   
    • AFP Innovation Funding - Project: " A Virtual Ward to Reduce Readmission after Discharge," Women's College Hospital (Toronto, ON). Total Funding: $28,379 (2010 - 2011)
    • Canadian Institutes of Health Research Operating Grant Competition - Project: "A Pilot Study Assessing Feasibility of a Randomized, Placebo-controlled Trial of Low Molecular Weight-Heparin for Postpartum Prophylaxis in Women at Risk of Developing Venous Thromboembolism." Co-investigator. Total Funding: $450,000 (2010 - 2012)  
    • Canadian Institutes of Health Research Control of Hypertension in Pregnancy Study. Co-investigator. (2009 - 2013)
    Honours & Awards
    • 2008/7 - 2009/6 Undergraduate Education Award, General Internal Medicine, Dept of Medicine, Faculty of Medicine Women's College Hospital. Description: In recognition of excellence in teaching, educational leadership and education administration at the undergraduate level.

    • 2004/9 - Young Investigator's Award - Distinction, Sunnybrook and Women's Health Sciences Centre

    • 2002/7 - 2003/1 Marion Hillard Award-School Fees, Women's College Hospital

    • 1999/1 - 2000/2 Marion Hillard Award-School Fees, Women's College Hospital

    • 1996/7 - 1998/6 MRC University-Industry Training Award, Women's College Hospital

    Research Group Members
    • Morgan Barber - Trainee

    • Sura Alwan - Trainee

    • Cesar Ballesteros - Trainee