• Langer, Monica


    Investigator, BC Children's Hospital
    Clinical Instructor, Department of Surgery, Division of Pediatric Surgery, University of British Columbia 

    Degrees / Designations
    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    604-875-2345 ext. 2810
    Lab Phone
    Robyn Walker
    Assistant Phone
    Mailing Address

    BC Children's Hospital
    Room KO-134
    4480 Oak St
    Vancouver, BC  V6H 3V4

    Affiliate Websites
    Research Areas
    • Clinical research 
    • Global health and global surgery 
    • Rare childhood tumors

    I am interested in developing unique, context-specific approaches to caring for children with common pediatric surgical problems in low income countries. Specifically I am starting a study to see if simple interventions can improve the survival of babies born with gastroschisis in Uganda.

    Current Projects

    My clinical research interests focus on surgical treatment of congenital anomalies and childhood cancers, with a particular interest in low-income settings. I am starting a clinical trial for gastroschisis patient care in Uganda, in an effort to address extremely high (98%) mortality of children with gastroschisis in this setting. The focus of the trial is to develop and test low-cost interventions designed to increase survival through improved pre-hospital and peri-operative care, as well as testing novel nutritional treatments which may be feasible in a low-income country (LIC). This pilot study may allow development of a multi-center study of surgical treatment congenital anomalies in LICs in Sub-Saharan Africa. The goal is to start this study in 2017. 

    Currently I am working with a group of pediatric surgeons across the United States as part of the Childhood Cancer Database Research (CCDR) team, investigating adult types of cancers in pediatric patients in an attempt to understand the biology, behavior and best treatment for children and young adults with these tumors. My projects focus on colorectal cancer, carcinoid tumors, and pancreatic cancer in children. I am also interested in studying outcomes from different central venous lines in children with cancer to determine if there is evidence to guide catheter choice and maintenance. 

    I am particularly interested in surgical disease and treatment in developing countries. My interest focuses both assessing the burden of disease as well as strategies with education and international participation to effect positive change in this arena. 

    Selected Publications
    1. Poles GC, Clark DE, Mayo SW, Beierle EA, Doski J, Goldfarb M, Gow K, Nuchtern J, Vasudevan SV, Goldin A, Langer M. Colorectal carcinoma in pediatric patients: A comparison with adult tumors, treatment and outcomes from the National Cancer Database. Journal of Pediatric Surgery 2016 51 1061-1066.
    2. Ozgediz D, Langer M, Kisa P, Poenaru D. Pediatric surgery as an essential component of global child health. In Seminars in Pediatric Surgery 2015 Sep 15. WB Saunders.
    3. Rojas Y, Shi YX, Zhang W, Beierle EA, Doski JJ, Goldfarb M, Goldin AB, Gow KW, Langer M, Vasudevan SA, Nuchtern JG. Primary malignant pulmonary tumors in children: a review of the national cancer data base. Journal of Pediatric Surgery 2015 50(6), 1004-1008.
    4. Butler MW, Ozgediz D, Poenaru D, Ameh E, Andrawes S, Azzie G, Borgstein E, DeUgarte DA, Elhalaby E, Ganey ME, Gerstle JT, Hansen EN, Hesse A, Lakhoo K, Krishnaswami S, Langer M, Levitt M, Meier D, Minocha A, Nwomeh BC, Abdur-Rahman LO, Rothstein D, Sekabira J. The Global Paediatric Surgery Network: A Model of Subspecialty Collaboration Within Global Surgery. World J Surg (2015) 39:335–342
    5. Sadler C, Gow KW, Beierle EA, Doski JJ, Langer M, Nuchtern JG, Vasudevan SA, Goldfarb M. Parathyroid carcinoma in more than 1,000 patients: A population-level analysis. Surgery 2014 Dec 156 (6): 1622 - 1630
    6. Badrinath, R, Kakembo, N, Kisa, P, Langer, M, Ozgediz, D, Sekabira, J. Outcomes and unmet need for neonatal surgery in a resource-limited environment: estimates of global health disparities from Kampala, Uganda.Journal of Pediatric Surgery 2014
    7. Blair, GK, Duffy D, Birabwe-Male D, Sekabira J, Reimer E, Koyle M, Hudson GR, Stanger J, Langer M, Eeson G, Gan H, McLean S, Kanaroglou N, Kisa P, Kakembo N, Lidstone K. Pediatric surgical camps as one model of global surgical partnership: A Way Forward. Journal of Pediatric Surgery. 2014 May 49: 786-790.
    8. Agus MS, Steil GM, Wypij D, Costello JM, Laussen PC, Langer M, Alexander JL, Scoppettuolo LA, Pigula FA, Charpie JR, Ohye RG, Gaies MG; SPECS Study Investigators. Tight glycemic control versus standard care after pediatric cardiac surgery.New England Journal of Medicine. 2012 Sep 27;367(13):1208-19.
    Honours & Awards
    Research Group Members