Recent Publications

Mehrabadi A, Hutcheon JA, Lee L, Kramer MS, Liston RM, Joseph KS. Epidemiological investigation of a temporal increase in atonic postpartum haemorrhage: a population-based retrospective cohort study. BJOG. 2013 Jun;120(7):853-62

Hanna CW, McFadden DE, Robinson WP. DNA methylation profiling of placental villi from karyotypically normal miscarriage and recurrent miscarriage. Am J Pathol. 2013 Jun;182(6):2276-84

Munro S, Kornelsen J, Grzybowski S. Models of maternity care in rural environments: barriers and attributes of interprofessional collaboration with midwives. Midwifery.  2013 Jun;29(6):646-52.

Wu EX, Wilson AD, Wong EC, Havelock JC, Ma S. Maternal origin of 47,XXY and confined placental mosaicism 47,XXY/48,XXY,+13 in an infant conceived through IVF. J Assist Reprod Genet. 2013 Jun;30(6):807-12.

Rurak D, Bessette NW. Changes in fetal lamb arterial blood gas and acid-base status with advancing gestation. Am J Physiol Regul Integr Comp Physiol. 2013 May 15;304(10):R908-16.

Staff AC, Benton SJ, von Dadelszen P, Roberts JM, Taylor RN, Powers RW, Charnock-Jones DS, Redman CW. Redefining preeclampsia using placenta-derived biomarkers. Hypertension.  2013 May;61(5):932-42

Joseph KS, Kinniburgh B, Hutcheon JA, Mehrabadi A, Basso M, Davies C, Lee L. Determinants of increases in stillbirth rates from 2000 to 2010. CMAJ. 2013 May 14;185(8):E345-51

Hogg K, Blair JD, McFadden DE, von Dadelszen P, Robinson WP. Early onset pre-eclampsia is associated with altered DNA methylation of cortisol-signalling and steroidogenic genes in the placenta. PLoS One. 2013 May 7;8(5):e62969.

Hutcheon JA, Platt RW, Abrams B, Himes KP, Simhan HN, Bodnar LM. A weight-gain-for-gestational-age z score chart for the assessment of maternal weight gain in pregnancy. Am J Clin Nutr. 2013 May;97(5):1062-7

Murphy KE, Willan AR, Hannah ME, Ohlsson A, Kelly EN, Matthews SG, Saigal S, Asztalos E, Ross S, Delisle MF, Amankwah K, Guselle P, Gafni A, Lee SK, Armson BA; Multiple Courses of Antenatal Corticosteroids for Preterm Birth Study Collaborative Group. Effect of antenatal corticosteroids on fetal growth and gestational age at birth. Obstet Gynecol. 2012 May;119(5):917-23.

Magee L, von Dadelszen P. Prevention and treatment of postpartum hypertension. Cochrane Database Syst Rev. 2013 Apr 30;4:CD004351.

Cheng JC, Qiu X, Chang HM, Leung PC. HER2 mediates epidermal growth factor-induced down-regulation of E-cadherin in human ovarian cancer cells. Biochem Biophys Res Commun. 2013 Apr 26;434(1):81-6.

Schroeder DI, Blair JD, Lott P, Yu HO, Hong D, Crary F, Ashwood P, Walker C, Korf I, Robinson WP, LaSalle JM. The human placenta methylome. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6037-42.

Lisonkova S, Paré E, Joseph KS. Does advanced maternal age confer a survival advantage to infants born at early gestation? BMC Pregnancy Childbirth.2013 Apr 8;13:87.

Rurak D, Wittman B. Real-time ultrasound assessment of body and breathing movements and abdominal diameter in fetal lambs from 55 days of gestation to term. Reprod Sci. 2013 Apr;20(4):414-25.

Vinall J, Grunau RE, Brant R, Chau V, Poskitt KJ, Synnes AR, Miller SP. Slower postnatal growth is associated with delayed cerebral cortical maturation in preterm newborns. Sci Transl Med. 2013 Jan 16;5(168):168ra8.

Lu E, Zhao Y, Zhu F, van der Kop ML, Synnes A, Dahlgren L, Sadovnick AD, Sayao AL, Tremlett H; British Columbia Multiple Sclerosis Clinic Neurologists. Birth hospitalization in mothers with multiple sclerosis and their newborns. Neurology. 2013 Jan 29;80(5):447-52.

Young C, von Dadelszen P, Alfirevic Z. Instruments for chorionic villus sampling for prenatal diagnosis. Cochrane Database Syst Rev. 2013 Jan 31;1:CD000114.

Payne B, Hodgson S, Hutcheon JA, Joseph KS, Li J, Lee T, Magee LA, Qu Z, von Dadelszen P; PIERS Study Group. Performance of the fullPIERS model in predicting adverse maternal outcomes in pre-eclampsia using patient data from the PIERS (Pre-eclampsia Integrated Estimate of RiSk) cohort, collected on admission. BJOG. 2013 Jan;120(1):113-8.

Hall JG. Uterine structural anomalies and arthrogryposis-death of an urban legend. Am J Med Genet A. 2013 Jan;161A(1):82-8.

Lee HR, Jeung EB, Cho MH, Kim TH, Leung PC, Choi KC Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors. J Cell Mol Med.2013 Jan;17(1):1-11

Cheung LW, Yung S, Chan TM, Leung PC, Wong AS. Targeting gonadotropin-releasing hormone receptor inhibits the early step of ovarian cancer metastasis by modulating tumor-mesothelial adhesion. Mol Ther. 2013 Jan;21(1):78-90.

Novakovic B, Gordon L, Robinson WP, Desoye G, Saffery R. Glucose as a fetal nutrient: dynamic regulation of several glucose transporter genes by DNA methylation in the human placenta across gestation. J Nutr Biochem. 2013 Jan;24(1):282-8

Joseph KS, D'Alton M. Theoretical and empirical justification for current rates of iatrogenic delivery at late preterm gestation. Paediatr Perinat Epidemiol. 2013 Jan;27(1):2-6.

Cuckle H, von Dadelszen P, Ghidini A. Current controversies in prenatal diagnosis 4: pregnancy complications due to placental vascular disease (pre-eclampsia, FGR): are we ready for prevention? Prenat Diagn. 2013 Jan;33(1):17-20

Filges I, Hall JG. Failure to identify antenatal multiple congenital contractures and fetal akinesia--proposal of guidelines to improve diagnosis. Prenat Diagn. 2013 Jan;33(1):61-74.

Stritzke AI, Smyth J, Synnes A, Lee SK, Shah PS. Transfusion-associated necrotising enterocolitis in neonates. Arch Dis Child Fetal Neonatal Ed. 2013 Jan;98(1):F10-4.

Cheng JC, Chang HM, Leung PC. Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells. Oncogene. 2013 Feb 21;32(8):1041-9.

Jahanfar S, Janssen PA, Howard LM, Dowswell T. Interventions for preventing or reducing domestic violence against pregnant women. Cochrane Database Syst Rev. 2013 Feb 28;2:CD009414.

Cheng JC, Klausen C, Leung PC. Hypoxia-inducible factor 1 alpha mediates epidermal growth factor-induced down-regulation of E-cadherin expression and cell invasion in human ovarian cancer cells. Cancer Lett. 2013 Feb 28;329(2):197-206.

Langlois S, Brock JA; Genetics Committee, Wilson RD, Audibert F, Brock JA, Carroll J, Cartier L, Gagnon A, Johnson JA, Langlois S, Macdonald W, Murphy-Kaulbeck L, Okun N, Pastuck M, Senikas V. Current status in non-invasive prenatal detection of down syndrome, trisomy 18, and trisomy 13 using cell-free DNA in maternal plasma. J Obstet Gynaecol Can. 2013 Feb;35(2):177-81.

Mayer C, Joseph KS Fetal growth: a review of terms, concepts and issues relevant to obstetrics. Ultrasound Obstet Gynecol. 2013 Feb;41(2):136-45.

Zwicker JG, Grunau RE, Adams E, Chau V, Brant R, Poskitt KJ, Synnes A, Miller SP. Score for neonatal acute physiology-II and neonatal pain predict corticospinal tract development in premature newborns. Pediatr Neurol. 2013 Feb;48(2):123-129.e1.

Yuen RK, Chen B, Blair JD, Robinson WP, Nelson DM. Hypoxia alters the epigenetic profile in cultured human placental trophoblasts. Epigenetics. 2013 Feb;8(2):192-202.

Zwicker JG, Yoon SW, Mackay M, Petrie-Thomas J, Rogers M, Synnes AR. Perinatal and neonatal predictors of developmental coordination disorder in very low birthweight children. Arch Dis Child. 2013 Feb;98(2):118-22.

Price ME, Cotton AM, Lam LL, Farré P, Emberly E, Brown CJ, Robinson WP, Kobor MS. Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium Human Methylation450 BeadChip array. Epigenetics Chromatin. 2013 Mar 3;6(1):4.

Hogg K, Blair JD, von Dadelszen P, Robinson WP. Hypomethylation of the LEP gene in placenta and elevated maternal leptin concentration in early onset pre-eclampsia. Mol Cell Endocrinol. 2013 Mar 10;367(1-2):64-73.

Lu E, Wang BW, Guimond C, Synnes A, Sadovnick AD, Dahlgren L, Traboulsee A, Tremlett H. Safety of disease-modifying drugs for multiple sclerosis in pregnancy: current challenges and future considerations for effective pharmacovigilance. Expert Rev Neurother. 2013 Mar;13(3):251-60.

Oh HK, Choi YS, Yang YI, Kim JH, Leung PC, Choi JH. Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways. Mol Hum Reprod. 2013 Mar;19(3):160-8.

Rurak D, Wittman B. Real-time ultrasound assessment of body and breathing movements and abdominal diameter in fetal lambs from 55 days of gestation to term. Reprod Sci. 2013 Mar;20(4):414-25.

Janssen PA, Desmarais SL Development and psychometric properties of the Early Labour Experience Questionnaire (ELEQ). Midwifery. 2013 Mar;29(3):181-9.

Janssen PA, Desmarais SL. Women's experience with early labour management at home vs. in hospital: a randomised controlled trial. Midwifery. 2013 Mar;29(3):190-4

Lalani S, Firoz T, Magee LA, Sawchuck D, Payne B, Gordon R, Vidler M, von Dadelszen P. Pharmacotherapy for preeclampsia in low and middle income countries: an analysis of essential medicines lists. J Obstet Gynaecol Can. 2013 Mar;35(3):215-23.

Pugash D, Langlois S, Power P, Demos M Absent cavum with intact septum pellucidum and corpus callosum may indicate midline brain abnormalities. Ultrasound Obstet Gynecol. 2013 Mar;41(3):343-4.

Chang HM, Cheng JC, Leung PC Theca-derived BMP4 and BMP7 down-regulate connexin43 expression and decrease gap junction intercellular communication activity in immortalized human granulosa cells. J Clin Endocrinol Metab. 2013 Mar;98(3):E437-45.

Cheng JC, Klausen C, Leung PC. Overexpression of wild-type but not C134W mutant FOXL2 enhances GnRH-induced cell apoptosis by increasing GnRH receptor expression in human granulosa cell tumors. PLoS One. 2013;8(1):e55099.

Lau MT, So WK, Leung PC. Fibroblast Growth Factor 2 Induces E-Cadherin Down-Regulation via PI3K/Akt/mTOR and MAPK/ERK Signaling in Ovarian Cancer Cells. PLoS One. 2013;8(3):e59083.