Cyrus Boelman

MD

Investigator, BC Children's Hospital

Research focuses primarily on Epilepsy in the pediatric population, as well as epilepsy genetics.

Academic Affiliations

  • Clinical Assistant Professor, Division of Neurology, Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Childhood Diseases
  • Research Group(s): Rare Diseases

Contact Information

Location

4500 Oak St, Vancouver, BC, Canada, V6H 3N1

Putting control into parents' hands: Parent experiences with a genomic results e-booklet

Journal of Genetic Counseling

Shelin Adam and Patricia Gombas and Michelle Demos and Cyrus Boelman and Mary B. Connolly and Kyrstin Lavelle and Jan M. Friedman and Alison M. Elliott and Patricia Birch

DOI: 10.1002/jgc4.70095

08 / 2025

STXBP1-Related Disorders: Clinical Presentation, Molecular Function, Treatment, and Future Directions

Genes

Alexander Freibauer and Mikayla Wohlleben and Cyrus Boelman

DOI: 10.3390/genes14122179

12 / 2023

Case reports: novel TUBG1 mutations with milder neurodevelopmental presentations

BMC Medical Genetics

Yue T. K. Yuen and Ilaria Guella and Elke Roland and Michael Sargent and Cyrus Boelman

DOI: 10.1186/s12881-019-0827-6

12 / 2019

Genomic Context Analysis of de Novo STXBP1 Mutations Identifies Evidence of Splice Site DNA-Motif Associated Hotspots

G3: Genes|Genomes|Genetics

Mohammed Uddin and Marc Woodbury-Smith and Ada J. S. Chan and Ammar Albanna and Berge Minassian and Cyrus Boelman and Stephen W. Scherer

DOI: 10.1534/g3.118.200080

02 / 2018

Global characterization of copy number variants in epilepsy patients from whole genome sequencing

Jean Monlong and Simon L. Girard and Caroline Meloche and Maxime Cadieux-Dion and Danielle M. Andrade and Ron G. Lafreniere and Micheline Gravel and Dan Spiegelman and Alexandre Dionne-Laporte and Cyrus Boelman and Fadi Hamdan and Jacques L. Michaud and Guy Rouleau and Berge A. Minassian and Guillaume Bourque and Patrick Cossette

DOI: 10.1101/199224

10 / 2017

Clinical Experience With Perampanel for Refractory Pediatric Epilepsy in One Canadian Center

Journal of Child Neurology

Anita N. Datta and Qi Xu and Shafina Sachedina and Cyrus Boelman and Linda Huh and Mary B. Connolly

DOI: 10.1177/0883073817709195

05 / 2017

Increased subcortical oligodendroglia-like cells in pharmacoresistant focal epilepsy in children correlate with extensive epileptogenic zones

Epilepsia

Satoru Sakuma and William C. Halliday and Ruka Nomura and Shiro Baba and Yosuke Sato and Kazuo Okanari and Midori Nakajima and Elysa Widjaja and Cyrus Boelman and Ayako Ochi and O. Carter Snead and James T. Rutka and James Drake and Steven Miller and Hiroshi Otsubo

DOI: 10.1111/epi.13590

11 / 2016

A.01 Targeted analysis of whole exome sequencing and genotype-phenotype correlation in epileptic encephalopathies

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

SE Buerki and EB Toyota and I Guella and M McKenzie and D Evans and S Adam and MI van Allen and C Boelman and G Horvath and CD Van Karnebeek and P Eydoux and L Huh and A Datta and KA Selby and A Michoulas and TN Nelson and MJ Farrer and MB Demos and MB Connolly

DOI: 10.1017/cjn.2016.53

06 / 2016

EEG in asymptomatic relatives of idiopathic epilepsy; a prospective study

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

BM Duaa and C Boelman and L Brunga and BA Minassian and D Andrade

DOI: 10.1017/cjn.2015.128

05 / 2015

KCNQ2 mutations: genotype-phenotype association beyond epilepsy

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

SE Buerki and GA Horwath and MI Van Allen and A Datta and C Boelman and Z Abu Sharar and B Sayson and MB Connolly and CD van Karnebeek and MK Demos

DOI: 10.1017/cjn.2015.66

05 / 2015

Spatial relationship between fast and slow components of ictal activities and interictal epileptiform discharges in epileptic spasms

Clinical Neurophysiology

Akiyama, T. and Akiyama, M. and Kobayashi, K. and Okanishi, T. and Boelman, C.G. and Nita, D.A. and Ochi, A. and Go, C.Y. and Snead, O.C. and Rutka, J.T. and Drake, J.M. and Chuang, S. and Otsubo, H.

DOI: 10.1016/j.clinph.2014.12.005

Faulty cardiac repolarization reserve in alternating hemiplegia of childhood broadens the phenotype

Brain

Jaffer, F. and Avbersek, A. and Vavassori, R. and Fons, C. and Campistol, J. and Stagnaro, M. and De Grandis, E. and Veneselli, E. and Rosewich, H. and Gianotta, M. and Zucca, C. and Ragona, F. and Granata, T. and Nardocci, N. and Mikati, M. and Helseth, A.R. and Boelman, C. and Minassian, B.A. and Johns, S. and Garry, S.I. and Scheffer, I.E. and Gourfinkel-An, I. and Carrilho, I. and Aylett, S.E. and Parton, M. and Hanna, M.G. and Houlden, H. and Neville, B. and Kurian, M.A. and Novy, J. and Sander, J.W. and Lambiase, P.D. and Behr, E.R. and Schyns, T. and Arzimanoglou, A. and Cross, J.H. and Kaski, J.P. and Sisodiya, S.M.

DOI: 10.1093/brain/awv243

Antithrombotic therapy for secondary stroke prevention in bacterial meningitis in children

Journal of Pediatrics

Boelman, C. and Shroff, M. and Yau, I. and Bjornson, B. and Richrdson, S. and Deveber, G. and Macgregor, D. and Moharir, M. and Askalan, R.

DOI: 10.1016/j.jpeds.2014.06.013

Preictal surrender of post-spike slow waves to spike-related high-frequency oscillations (80-200 Hz) is associated with seizure initiation

Epilepsia

Sato, Y. and Doesburg, S.M. and Wong, S.M. and Boelman, C. and Ochi, A. and Otsubo, H.

DOI: 10.1111/epi.12728

Identical ATP1A3 mutation causes alternating hemiplegia of childhood and rapid-onset dystonia parkinsonism phenotypes

Pediatric Neurology

Boelman, C. and Lagman-Bartolome, A.M. and MacGregor, D.L. and McCabe, J. and Logan, W.J. and Minassian, B.A.

DOI: 10.1016/j.pediatrneurol.2014.08.015

Interictal high frequency oscillations correlating with seizure outcome in patients with widespread epileptic networks in tuberous sclerosis complex

Epilepsia

Okanishi, T. and Akiyama, T. and Tanaka, S.-I. and Mayo, E. and Mitsutake, A. and Boelman, C. and Go, C. and Snead, O.C. and Drake, J. and Rutka, J. and Ochi, A. and Otsubo, H.

DOI: 10.1111/epi.12761

Adjunctive dexamethasone in adults with meningococcal meningitis

Neurology

Boelman, C.G.

DOI: 10.1212/01.wnl.0000430451.92743.a5

Statistical mapping analysis of lesion location and neurological disability in multiple sclerosis: application to 452 patient data sets

NeuroImage

Arnaud Charil and Alex P Zijdenbos and Jonathan Taylor and Cyrus Boelman and Keith J Worsley and Alan C Evans and Alain Dagher

DOI: 10.1016/s1053-8119(03)00117-4

07 / 2003

Correlation between MS lesions and disability using 3D voxel-based statistical analysis

NeuroImage

Arnaud Charil and Alex Zijdenbos and Cyrus Boelman and Jonathan Taylor and Keith J. Worsley and Alan C. Evans and Alain Dagher

DOI: 10.1016/s1053-8119(00)91601-x

05 / 2000

The Personalized Medicine in the Treatment of Epilepsy

Identification of Genes Predisposing to the disease and to resistance to anti-epileptic treatments study is looking to identify genetic mutations responsible for various forms of epilepsy, as well as to understand the impact of genetic analysis and whole genome sequencing which will be used to study the participant's genes or their genome. This can lead to a better understanding of the disease and enable earlier diagnosis, as well as develop understanding of the genetic factors involved in anti-epileptic medication response at a personalized level.

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