Overview

In 1995, as a new graduate student in the department of psychiatry, I began investigating the morphological phenomena of schizophrenia and related psychotic disorders. These initial in-vivo investigations involved the application of CT (Computed Tomography) imaging to examine phenotypic characteristics of brain morphology in families affected by schizophrenia. Since that time, my research has moved forward into multi-modal applications of MRI (magnetic resonance imaging) to investigate the effects of antipsychotic medications on brain structure in schizophrenia, the relationships between structure, symptoms and cognition in psychotic disorders and first-episode psychosis, and more recently, the interactions between substance abuse, psychosis and systemic infections on brain morphology.

Currently, all my neuroimaging research data are obtained at UBC on the high-field research scanner, which produces exceptionally high quality scans and gives researchers the capability to examine physiological, biochemical and physical markers in the brain. This has allowed me, along with the residents and graduate students I work with, to examine the neurocircuitry and metabolic characteristics of psychotic disorders using diffusion tensor imaging and susceptibility-weighted imaging. My current projects involve the investigation of the effects of exercise on hipppocampal volume and vascularization in chronic schizophrenia patients and in adolescent psychosis patients. Additionally, I am involved in a large longitudinal imaging study of multi-diagnosis addiction, psychosis and infection subjects over the course of 5-8 years. Some of the goals of this study include investigating the interactions of life circumstances, addiction, mental illness and physical illnesses in an urban population, and how these interactions have affected quality of life, health care access, persistence of mental disorder/addictions and neurobiological integrity.

Publications

Changes in cortical grey matter volume with Cognitive Orientation to daily Occupational Performance intervention in children with developmental coordination disorder
Frontiers in Human Neuroscience
DOI: 10.3389/fnhum.2024.1316117
2024

Relationship between drug-induced movement disorders and psychosis in adults living in precarious housing or homelessness
Journal of Psychiatric Research
DOI: 10.1016/j.jpsychires.2024.01.003
2024

Multilayer depressive symptom networks in adults with bodily pain living in precarious housing or homelessness
European Archives of Psychiatry and Clinical Neuroscience
DOI: 10.1007/s00406-023-01664-0
2024

Differential sensitivity of intraindividual variability dispersion and global cognition in the prediction of functional outcomes and mortality in precariously housed and homeless adults
Clinical Neuropsychologist
DOI: 10.1080/13854046.2024.2325167
2024

Cortical grey matter volume differences in children with developmental coordination disorder compared to typically developing children
Frontiers in Human Neuroscience
DOI: 10.3389/fnhum.2024.1276057
2024

Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared with the general population
BMJ Neurology Open
DOI: 10.1136/bmjno-2022-000349
2023

Movement disorders associated with substance use in adults living in precarious housing or homelessness
Progress in Neuro-Psychopharmacology and Biological Psychiatry
DOI: 10.1016/j.pnpbp.2023.110795
2023

Use of Teletherapy for the Treatment of People with Psychotic Disorders During Covid-19 Confinement: Acceptability, Feasibility, and Challenges
Canadian Journal of Community Mental Health
DOI: 10.7870/cjcmh-2023-021
2023

Rasch analysis of the beck depression inventory in a homeless and precariously housed sample
Psychiatry Research
DOI: 10.1016/j.psychres.2023.115331
2023

Using serial position effects to investigate memory dysfunction in homeless and precariously housed persons
Clinical Neuropsychologist
Gicas, K.M. and Benitah, K. and Thornton, A.E. and Petersson, A.M. and Jones, P.W. and Stubbs, J.L. and Jones, A.A. and Panenka, W.J. and Lang, D.J. and Leonova, O. and Vila-Rodriguez, F. and Barr, A.M. and Buchanan, T. and Su, W. and Vertinsky, A.T. and Rauscher, A. and MacEwan, G.W. and Honer, W.G.
DOI: 10.1080/13854046.2023.2178513
2023

Pain, opioid use, depressive symptoms, and mortality in adults living in precarious housing or homelessness: a longitudinal prospective study
Pain
Andrea A. Jones and Lianne L. Cho and David D. Kim and Skye P. Barbic and Olga Leonova and Alexandra Byford and Tari Buchanan and Fidel Vila-Rodriguez and Ric M. Procyshyn and Donna J. Lang and A. Talia Vertinsky and G. William MacEwan and Alexander Rauscher and William J. Panenka and Allen E. Thornton and Alasdair M. Barr and Thalia S. Field and William G. Honer
DOI: 10.1097/j.pain.0000000000002619
11/2022

Dynamic networks of psychotic symptoms in adults living in precarious housing or homelessness
Psychological Medicine
Andrea A. Jones and Kristina M. Gicas and Sara Mostafavi and Melissa L. Woodward and Olga Leonova and Fidel Vila-Rodriguez and Ric M. Procyshyn and Alex Cheng and Tari Buchanan and Donna J. Lang and G. William MacEwan and William J. Panenka and Alasdair M. Barr and Allen E. Thornton and William G. Honer
DOI: 10.1017/S0033291720004444
10/2022

Characterizing Traumatic Brain Injury and Its Association with Losing Stable Housing in a Community-based Sample,Caractérisation d’une lésion cérébrale traumatique et de son association avec la perte d’un logement stable dans un échantillon communautaire
Canadian Journal of Psychiatry
Stubbs, J.L. and Thornton, A.E. and Gicas, K.M. and O?Connor, T.A. and Livingston, E.M. and Lu, H.Y. and Mehta, A.K. and Lang, D.J. and Vertinsky, A.T. and Field, T.S. and Heran, M.K. and Leonova, O. and Sahota, C.S. and Buchanan, T. and Barr, A.M. and MacEwan, G.W. and Rauscher, A. and Honer, W.G. and Panenka, W.J.
DOI: 10.1177/07067437211000665
2022

Traumatic brain injury in precariously housed persons: Incidence and risks
eClinicalMedicine
O'Connor, T.A. and Panenka, W.J. and Livingston, E.M. and Stubbs, J.L. and Askew, J. and Sahota, C.S. and Feldman, S.J. and Buchanan, T. and Xu, L. and Hu, X.J. and Lang, D.J. and Woodward, M.L. and Thornton, W.L. and Gicas, K.M. and Vertinsky, A.T. and Heran, M.K. and Su, W. and MacEwan, G.W. and Barr, A.M. and Honer, W.G. and Thornton, A.E.
DOI: 10.1016/j.eclinm.2022.101277
2022

Cerebellar and brainstem differences in children with developmental coordination disorder: A voxel-based morphometry study
Frontiers in Human Neuroscience
Gill, K.K. and Lang, D. and Zwicker, J.G.
DOI: 10.3389/fnhum.2022.921505
2022

Risk factors for hippocampal cavities in a marginally housed population
Hippocampus
Cheng, A.Y.T. and Stubbs, J.L. and Barr, A.M. and Gicas, K.M. and Su, W. and Thornton, A.E. and Lang, D.J. and Hamzah, Y. and Leonova, O. and MacEwan, W.G. and Rauscher, A. and Honer, W.G. and Panenka, W.J.
DOI: 10.1002/hipo.23450
2022

Cerebellar Differences after Rehabilitation in Children with Developmental Coordination Disorder
Brain Sciences
Gill, K.K. and Lang, D. and Zwicker, J.G.
DOI: 10.3390/brainsci12070856
2022

Differential age-associated brain atrophy and white matter changes among homeless and precariously housed individuals compared to the general population
medRxiv
Stubbs, J.L. and Jones, A.A. and Wolfman, D. and Chan, R.C.Y. and Vertinsky, A.T. and Heran, M.K. and Su, W. and Lang, D. and Field, T.S. and Gicas, K.M. and Woodward, M.L. and Thornton, A.E. and Barr, A.M. and Leonova, O. and MacEwan, G.W. and Rauscher, A. and Honer, W.G. and Panenka, W.J.
DOI: 10.1101/2021.11.03.21265661
2021

Component Processes of Decision Making in a Community Sample of Precariously Housed Persons: Associations With Learning and Memory, and Health-Risk Behaviors
Frontiers in Psychology
Baitz, H.A. and Jones, P.W. and Campbell, D.A. and Jones, A.A. and Gicas, K.M. and Giesbrecht, C.J. and Loken Thornton, W. and Barone, C.C. and Wang, N.Y. and Panenka, W.J. and Lang, D.J. and Vila-Rodriguez, F. and Leonova, O. and Barr, A.M. and Procyshyn, R.M. and Buchanan, T. and Rauscher, A. and MacEwan, G.W. and Honer, W.G. and Thornton, A.E.
DOI: 10.3389/fpsyg.2021.571423
2021

Characterization of Bodily Pain and Use of Both Prescription and Non-Prescription Opioids in Tenants of Precarious Housing
Substance Use and Misuse
Lei, M. and Rintoul, K. and Stubbs, J.L. and Kim, D.D. and Jones, A.A. and Hamzah, Y. and Procyshyn, R.M. and Gicas, K.M. and Cho, L.L. and Panenka, W.J. and Thornton, A.E. and Lang, D.J. and MacEwan, G.W. and Honer, W.G. and Barr, A.M.
DOI: 10.1080/10826084.2021.1958865
2021

Psychometric properties and correlates of the Beck Depression Inventory in a community-based and homeless or precariously housed sample
Journal of Affective Disorders Reports
Cho, L.L. and Jones, A.A. and Barbic, S. and Leonova, O. and Vila-Rodriguez, F. and Buchanan, T. and Lang, D.J. and William MacEwan, G. and Procyshyn, R.M. and Panenka, W.J. and Barr, A.M. and Thornton, A.E. and Gicas, K.M. and Honer, W.G.
DOI: 10.1016/j.jadr.2021.100229
2021

Effects of Aerobic, Resistance, and Combined Exercise Training on Psychiatric Symptom Severity and Related Health Measures in Adults Living With Schizophrenia: A Systematic Review and Meta-Analysis
Frontiers in Cardiovascular Medicine
DOI: 10.3389/fcvm.2021.753117
2021

Cerebral Small Vessel Disease, Risk Factors, and Cognition in Tenants of Precarious Housing.
Stroke
Zhou LW and Panenka WJ and Al-Momen G and Gicas KM and Thornton AE and Jones AA and Woodward M and Heran MKS and Vertinsky AT and Su W and Barr AM and MacEwan GW and Lang DJ and Field TS
DOI: 10.1161/strokeaha.120.030446
PubMed: 33019899
10/2020

Differential effects of cannabis exposure during early versus later adolescence on the expression of psychosis in homeless and precariously housed adults.
Progress in neuro-psychopharmacology & biological psychiatry
Gicas KM and Cheng A and Panenka WJ and Kim DD and Yau JC and Procyshyn RM and Stubbs JL and Jones AA and Bains S and Thornton AE and Lang DJ and Vertinsky AT and Rauscher A and Honer WG and Barr AM
DOI: 10.1016/j.pnpbp.2020.110084
PubMed: 32890696
09/2020

Cognitive decline and mortality in a community-based sample of homeless and precariously housed adults: 9-year prospective study.
BJPsych open
Gicas KM and Jones AA and Thornton AE and Petersson A and Livingston E and Waclawik K and Panenka WJ and Barr AM and Lang DJ and Vila-Rodriguez F and Leonova O and Procyshyn RM and Honer WG
DOI: 10.1192/bjo.2020.3
PubMed: 32043436
02/2020

Medial temporal lobe cortical changes in response to exercise interventions in people with early psychosis: A randomized controlled trial
Schizophrenia Research
Woodward, M.L. and Lin, J. and Gicas, K.M. and Su, W. and Hui, C.L.M. and Honer, W.G. and Chen, E.Y.H. and Lang, D.J.
DOI: 10.1016/j.schres.2020.05.043
2020

Decreased medial entorhinal cortical thickness in olanzapine exposed female rats is not ameliorated by exercise
Pharmacology Biochemistry and Behavior
Woodward, M.L. and Ker, A.H. and Barr, A.M. and Beasley, C.L. and Hercher, C. and Boyda, H.N. and Procyshyn, R.M. and Honer, W.G. and Lang, D.J.
DOI: 10.1016/j.pbb.2019.172834
2020

Amygdala Nuclei Volumes Are Selectively Associated With Social Network Size in Homeless and Precariously Housed Persons
Frontiers in Behavioral Neuroscience
Jones, P.W. and Thornton, A.E. and Jones, A.A. and Knerich, V.M. and Lang, D.J. and Woodward, M.L. and Panenka, W.J. and Su, W. and Barr, A.M. and Buchanan, T. and Honer, W.G. and Gicas, K.M.
DOI: 10.3389/fnbeh.2020.00097
2020

Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada
PLoS Medicine
Jones, A.A. and Gicas, K.M. and Seyedin, S. and Willi, T.S. and Leonova, O. and Vila-Rodriguez, F. and Procyshyn, R.M. and Smith, G.N. and Schmitt, T.A. and Vertinsky, A.T. and Buchanan, T. and Rauscher, A. and Lang, D.J. and MacEwan, G.W. and Lima, V.D. and Montaner, J.S.G. and Panenka, W.J. and Barr, A.M. and Thornton, A.E. and Honer, W.G.
DOI: 10.1371/journal.pmed.1003172
2020

A comparison of regional brain volumes and white matter connectivity in subjects with stimulant induced psychosis versus schizophrenia
Psychopharmacology
Alexander, P.D. and Gicas, K.M. and Cheng, A. and Lang, D.J. and Procyshyn, R.M. and Vertinsky, A.T. and Panenka, W.J. and Thornton, A.E. and Rauscher, A. and Wong, J.Y.X. and Chan, T. and Jones, A.A. and Vila-Rodriguez, F. and Honer, W.G. and Barr, A.M.
DOI: 10.1007/s00213-019-05298-w
2019

Neural correlates of symptom provocation in pediatric obsessive-compulsive disorder
NeuroImage: Clinical
Jaspers-Fayer, F. and Lin, S.Y. and Chan, E. and Ellwyn, R. and Lim, R. and Best, J. and Belschner, L. and Lang, D. and Heran, M.K.M. and Woodward, T.S. and Stewart, S.E.
DOI: 10.1016/j.nicl.2019.102034
2019

Prevalence and risk factors of brain infarcts and associations with cognitive performance in tenants of marginal housing
Journal of the American Heart Association
Zhou, L.W. and Panenka, W.J. and Jones, A.A. and Gicas, K.M. and Thornton, A.E. and Heran, M.K.S. and Volders, D. and Lang, D.J. and Vertinsky, A.T. and Rauscher, A. and Su, W. and Barr, A.M. and Macewan, G.W. and Honer, W.G. and Field, T.S.
DOI: 10.1161/JAHA.118.011412
2019

Volumes of the Hippocampal Formation Differentiate Component Processes of Memory in a Community Sample of Homeless and Marginally Housed Persons
Archives of Clinical Neuropsychology
Gicas, K.M. and Thornton, A.E. and Waclawik, K. and Wang, N. and Jones, A.A. and Panenka, W.J. and Lang, D.J. and Smith, G.N. and Vila-Rodriguez, F. and Leonova, O. and Barr, A.M. and Procyshyn, R.M. and Buchanan, T. and Su, W. and Vertinsky, A.T. and Rauscher, A. and Macewan, G.W. and Honer, W.G.
DOI: 10.1093/arclin/acy066
2019

Cognitive profiles and associated structural brain networks in a multimorbid sample of marginalized adults
PLoS ONE
Gicas, K.M. and Jones, A.A. and Panenka, W.J. and Giesbrecht, C. and Lang, D.J. and Vila-Rodriguez, F. and Leonova, O. and Barr, A.M. and Procyshyn, R.M. and Su, W. and Rauscher, A. and Vertinsky, A.T. and Buchanan, T. and Macewan, G.W. and Thornton, A.E. and Honer, W.G.
DOI: 10.1371/journal.pone.0218201
2019

Myelin Water Atlas: A Template for Myelin Distribution in the Brain
Journal of Neuroimaging
Liu, H. and Rubino, C. and Dvorak, A.V. and Jarrett, M. and Ljungberg, E. and Vavasour, I.M. and Lee, L.E. and Kolind, S.H. and MacMillan, E.L. and Traboulsee, A. and Lang, D.J. and Rauscher, A. and Li, D.K.B. and MacKay, A.L. and Boyd, L.A. and Kramer, J.L.K. and Laule, C.
DOI: 10.1111/jon.12657
2019

Parcellation of the human hippocampus based on gray matter volume covariance: Replicable results on healthy young adults
Human Brain Mapping
Ge, R. and Kot, P. and Liu, X. and Lang, D.J. and Wang, J.Z. and Honer, W.G. and Vila-Rodriguez, F.
DOI: 10.1002/hbm.24628
2019

Diffusion tensor imaging of neurocognitive profiles in a community cohort living in marginal housing
Brain and Behavior
Gicas, K.M. and Cheng, A. and Rawtaer, I. and Willi, T.S. and Panenka, W.J. and Lang, D.J. and Smith, G.N. and Vila-Rodriguez, F. and Leonova, O. and Giesbrecht, C.J. and Jones, A.A. and Barr, A.M. and Procyshyn, R.M. and Buchanan, T. and MacEwan, G.W. and Su, W. and Vertinsky, A.T. and Rauscher, A. and O?Rourke, N. and Loken Thornton, W. and Thornton, A.E. and Honer, W.G.
DOI: 10.1002/brb3.1233
2019

Characterizing traumatic brain injury and its association with homelessness in a community-based sample of precariously housed adults and youth
medRxiv
Stubbs, J.L. and Thornton, A.E. and Gicas, K.M. and O?Connor, T.A. and Livingston, E.M. and Lu, H.Y. and Mehta, A.K. and Lang, D.J. and Vertinsky, A.T. and Field, T.S. and Heran, M.K. and Leonova, O. and Buchanan, T. and Barr, A.M. and MacEwan, G.W. and Honer, W.G. and Panenka, W.J.
DOI: 10.1101/19004606
2019

Cognitive Impairment in Marginally Housed Youth: Prevalence and Risk Factors
Frontiers in Public Health
Waclawik, K. and Jones, A.A. and Barbic, S.P. and Gicas, K.M. and O'Connor, T.A. and Smith, G.N. and Leonova, O. and Mathias, S. and Barr, A.M. and Procyshyn, R.M. and Lang, D.J. and Woodward, M.L. and MacEwan, G.W. and Panenka, W.J. and Yamamoto, A. and Honer, W.G. and Thornton, A.E.
DOI: 10.3389/fpubh.2019.00270
2019

Clinical and functional characteristics of young adults living in single room occupancy housing: preliminary findings from a 10-year longitudinal study
Canadian Journal of Public Health
Barbic, S.P. and Jones, A.A. and Woodward, M. and Piercy, M. and Mathias, S. and Vila-Rodriguez, F. and Leonova, O. and Smith, G.N. and Buchanan, T. and Vertinsky, A.T. and Gillingham, S. and Panenka, W.J. and Rauscher, A. and Barr, A.M. and Procyshyn, R.M. and MacEwan, G.W. and Lang, D.J. and Thornton, A.E. and Heran, M.K. and Leon, A.M. and Krausz, M. and Honer, W.G.
DOI: 10.17269/s41997-018-0087-9
2018

Musical deficits and cortical thickness in people with schizophrenia
Schizophrenia Research
Fujito, R. and Minese, M. and Hatada, S. and Kamimura, N. and Morinobu, S. and Lang, D.J. and Honer, W.G. and Sawada, K.
DOI: 10.1016/j.schres.2018.01.027
2018

Structural brain changes in first episode mania with and without psychosis: Data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM)
World Journal of Biological Psychiatry
Keramatian, K. and Dhanoa, T. and McGirr, A. and Lang, D.J. and Honer, W.G. and Lam, R.W. and Yatham, L.N.
DOI: 10.1080/15622975.2016.1249950
2018

Reduced cardiovascular fitness associated with exposure to clozapine in individuals with chronic schizophrenia
Psychiatry Research
Kim, D.D. and Lang, D.J. and Procyshyn, R.M. and Woodward, M.L. and Kaufman, K. and White, R.F. and Honer, W.G. and Warburton, D.E.R.
DOI: 10.1016/j.psychres.2018.01.029
2018

Hippocampal volume and vasculature before and after exercise in treatment-resistant schizophrenia
Schizophrenia Research
Woodward, M.L. and Gicas, K.M. and Warburton, D.E. and White, R.F. and Rauscher, A. and Leonova, O. and Su, W. and Smith, G.N. and Thornton, A.E. and Vertinsky, A.T. and Phillips, A.A. and Goghari, V.M. and Honer, W.G. and Lang, D.J.
DOI: 10.1016/j.schres.2018.06.054
2018

Exercise-associated extrapyramidal symptoms during treatment with long-acting injectable antipsychotic medications: A case report
Clinical Schizophrenia & Related Psychoses
David D. Kim and Donna J. Lang and Darren E. R. Warburton and Alasdair M. Barr and Randall F. White and William G. Honer and Ric M. Procyshyn
DOI: 10.3371/csrp.dkdl.071317
08/2017

Structural brain markers are differentially associated with neurocognitive profiles in socially marginalized people with multimorbid illness.
Neuropsychology
Kristina M. Gicas and Chantelle J. Giesbrecht and William J. Panenka and Donna J. Lang and Geoffrey N. Smith and Fidel Vila-Rodriguez and Olga Leonova and Andrea A. Jones and Alasdair M. Barr and Ric M. Procyshyn and Tari Buchanan and G. William MacEwan and Wayne Su and A. Talia Vertinsky and Alexander Rauscher and William G. Honer and Allen E. Thornton
DOI: 10.1037/neu0000304
01/2017

Heart-rate response to alpha 2 -adrenergic receptor antagonism by antipsychotics
Clinical Autonomic Research
Kim, D.D. and Lang, D.J. and Warburton, D.E.R. and Woodward, M.L. and White, R.F. and Barr, A.M. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1007/s10286-017-0444-4
2017

Verbal memory improvement in first-episode psychosis APOE-e4 carriers: A pleiotropic effect?
Neuropsychiatric Disease and Treatment
Vila-Rodriguez, F. and Lang, D.J. and Baitz, H. and Gicas, K. and Thorton, A.E. and Ehmann, T.S. and Smith, G.N. and Barr, A.M. and Torres, I.J. and Kopala, L.C. and William Macewan, G. and Müller, D.J. and Kennedy, J.L. and Honer, W.G.
DOI: 10.2147/NDT.S150488
2017

The Hotel Study - Clinical and Health Service Effectiveness in a Cohort of Homeless or Marginally Housed Persons
Canadian Journal of Psychiatry
Honer, W.G. and Cervantes-Larios, A. and Jones, A.A. and Vila-Rodriguez, F. and Montaner, J.S. and Tran, H. and Nham, J. and Panenka, W.J. and Lang, D.J. and Thornton, A.E. and Vertinsky, T. and Barr, A.M. and Procyshyn, R.M. and Smith, G.N. and Buchanan, T. and Krajden, M. and Krausz, M. and Macewan, G.W. and Gicas, K.M. and Leonova, O. and Langheimer, V. and Rauscher, A. and Schultz, K.
DOI: 10.1177/0706743717693781
2017

Effects of exercise on serum triglycerides and symptoms of schizophrenia
Journal of Clinical Psychopharmacology
Kim, D.D. and Lang, D.J. and Warburton, D.E.R. and Barr, A.M. and Smith, G.N. and Thornton, A.E. and White, R.F. and Honer, W.G. and Procyshyn, R.M.
DOI: 10.1097/JCP.0000000000000648
2017

A comparison of psychotic symptoms in subjects with methamphetamine versus cocaine dependence
Psychopharmacology
Alexander, P.D. and Gicas, K.M. and Willi, T.S. and Kim, C.N. and Boyeva, V. and Procyshyn, R.M. and Smith, G.N. and Thornton, A.E. and Panenka, W.J. and Jones, A.A. and Vila-Rodriguez, F. and Lang, D.J. and William MacEwan, G. and Honer, W.G. and Barr, A.M.
DOI: 10.1007/s00213-017-4551-7
2017

Diagnosis and body mass index effects on hippocampal volumes and neurochemistry in bipolar disorder
Translational Psychiatry
Bond, D.J. and Silveira, L.E. and MacMillan, E.L. and Torres, I.J. and Lang, D.J. and Su, W. and Honer, W.G. and Lam, R.W. and Yatham, L.N.
DOI: 10.1038/tp.2017.42
2017

Characterization of white matter integrity deficits in cocaine-dependent individuals with substance-induced psychosis compared with non-psychotic cocaine users
Addiction Biology
Willi, T.S. and Barr, A.M. and Gicas, K. and Lang, D.J. and Vila-Rodriguez, F. and Su, W. and Thornton, A.E. and Leonova, O. and Giesbrecht, C.J. and Procyshyn, R.M. and Rauscher, A. and MacEwan, W.G. and Honer, W.G. and Panenka, W.J.
DOI: 10.1111/adb.12363
2017

Traumatic Brain Injury in a Community-Based Cohort of Homeless and Vulnerably Housed Individuals
Journal of Neurotrauma
Schmitt, T. and Thornton, A.E. and Rawtaer, I. and Barr, A.M. and Gicas, K.M. and Lang, D.J. and Vertinsky, A.T. and Rauscher, A. and Procyshyn, R.M. and Buchanan, T. and Cheng, A. and Mackay, S. and Leonova, O. and Langheimer, V. and Field, T.S. and Heran, M.K. and Vila-Rodriguez, F. and O'Connor, T.A. and Macewan, G.W. and Honer, W.G. and Panenka, W.J.
DOI: 10.1089/neu.2017.5076
2017

Subcortical structural volumes in recently remitted first episode mania
Journal of Affective Disorders
Arumugham, S.S. and Torres, I.J. and Lang, D.J. and Su, W. and Lam, R.W. and Honer, W.G. and Yatham, L.N.
DOI: 10.1016/j.jad.2017.06.051
2017

Prevalence of brain microbleeds in Alzheimer disease: A systematic review and meta-analysis on the influence of neuroimaging techniques
American Journal of Neuroradiology
Sepehry, A.A. and Lang, D. and Hsiung, G.-Y. and Rauscher, A.
DOI: 10.3174/ajnr.A4525
2016

Subcortical grey matter alterations in cocaine dependent individuals with substance-induced psychosis compared to non-psychotic cocaine users
Schizophrenia Research
Willi, T.S. and Lang, D.J. and Honer, W.G. and Smith, G.N. and Thornton, A.E. and Panenka, W.J. and Procyshyn, R.M. and Vila-Rodriguez, F. and Su, W. and Vertinsky, A.T. and Leonova, O. and Rauscher, A. and MacEwan, G.W. and Barr, A.M.
DOI: 10.1016/j.schres.2016.08.001
2016

Relationship between body mass index and hippocampal glutamate/glutamine in bipolar disorder
British Journal of Psychiatry
DOI: 10.1192/bjp.bp.115.163360
2016

RE: Elucidating pretreatment cognitive impairment in breast cancer patients: The impact of cancer-related post-traumatic stress
Journal of the National Cancer Institute
Sepehry, A.A. and Tyldesley, S. and Davis, M.K. and Simmons, C. and Rauscher, A. and Lang, D.J.-M.
DOI: 10.1093/jnci/djw048
2016

Microbleeds in Alzheimer's disease: A neuropsychological overview and meta-analysis
Canadian Journal of Neurological Sciences
Sepehry, A.A. and Rauscher, A. and Hsiung, G.-Y. and Lang, D.J.
DOI: 10.1017/cjn.2016.296
2016

White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection Psychiatry
BMC Research Notes
Tang, V.M. and Lang, D.J. and Giesbrecht, C.J. and Panenka, W.J. and Willi, T. and Procyshyn, R.M. and Vila-Rodriguez, F. and Jenkins, W. and Lecomte, T. and Boyda, H.N. and Aleksic, A. and Macewan, G.W. and Honer, W.G. and Barr, A.M.
DOI: 10.1186/s13104-015-1501-5
2015

Hippocampal subfield volumes in first episode and chronic schizophrenia
PLoS ONE
Kawano, M. and Sawada, K. and Shimodera, S. and Ogawa, Y. and Kariya, S. and Lang, D.J. and Inoue, S. and Honer, W.G.
DOI: 10.1371/journal.pone.0117785
2015

Cortical morphology and early adverse birth events in men with first-episode psychosis
Psychological Medicine
Smith, G.N. and Thornton, A.E. and Lang, D.J. and Macewan, G.W. and Kopala, L.C. and Su, W. and Honer, W.G.
DOI: 10.1017/S003329171400292X
2015

Mortality from treatable illnesses in marginally housed adults: A prospective cohort study
BMJ Open
Jones, A.A. and Vila-Rodriguez, F. and Leonova, O. and Langheimer, V. and Lang, D.J. and Barr, A.M. and Procyshyn, R.M. and Smith, G.N. and Schultz, K. and Buchanan, T. and Krausz, M. and Montaner, J.S. and Macewan, G.W. and Rauscher, A. and Panenka, W.J. and Thornton, A.E. and Honer, W.G.
DOI: 10.1136/bmjopen-2015-008876
2015

Neurocognitive profiles of marginally housed persons with comorbid substance dependence, viral infection, and psychiatric illness
Journal of Clinical and Experimental Neuropsychology
Gicas, K.M. and Vila-Rodriguez, F. and Paquet, K. and Barr, A.M. and Procyshyn, R.M. and Lang, D.J. and Smith, G.N. and Baitz, H.A. and Giesbrecht, C.J. and Montaner, J.S. and Krajden, M. and Krausz, M. and MacEwan, G.W. and Panenka, W.J. and Honer, W.G. and Thornton, A.E.
DOI: 10.1080/13803395.2014.963519
2014

Body mass index-related regional gray and white matter volume reductions in first-episode mania patients
Biological Psychiatry
Bond, D.J. and Ha, T.H. and Lang, D.J. and Su, W. and Torres, I.J. and Honer, W.G. and Lam, R.W. and Yatham, L.N.
DOI: 10.1016/j.biopsych.2013.08.030
2014

Assessment of arterial stiffness among schizophrenia-spectrum disorders using aortic pulse wave velocity and arterial compliance: A pilot study
Psychiatry Research
Phillips, A.A. and Warburton, D.E.R. and Flynn, S.W. and Fredrikson, D. and Lang, D.J.
DOI: 10.1016/j.psychres.2013.10.020
2014

48 echo T2 myelin imaging of white matter in first-episode schizophrenia: Evidence for aberrant myelination
NeuroImage: Clinical
Lang, D.J.M. and Yip, E. and Mackay, A.L. and Thornton, A.E. and Vila-Rodriguez, F. and Macewan, G.W. and Kopala, L.C. and Smith, G.N. and Laule, C. and Macrae, C.B. and Honer, W.G.
DOI: 10.1016/j.nicl.2014.10.006
2014

Management of Medication-Related Cardiometabolic Risk in Patients with Severe Mental Illness
Current Cardiovascular Risk Reports
Lang, D.J. and Barr, A.M. and Procyshyn, R.M.
DOI: 10.1007/s12170-013-0321-1
2013

Relationships among depression, PTSD, methamphetamine abuse, and psychosis
Journal of Dual Diagnosis
Lecomte, T. and Paquin, K. and Mueser, K.T. and MacEwan, G.W. and Goldner, E. and Thornton, A.E. and Brink, J. and Lang, D. and Kang, S. and Barr, A.M. and Honer, W.G.
DOI: 10.1080/15504263.2013.778930
2013

Predictors of persistent psychotic symptoms in persons with methamphetamine abuse receiving psychiatric treatment
Journal of Nervous and Mental Disease
Lecomte, T. and Mueser, K.T. and Macewan, W. and Thornton, A.E. and Buchanan, T. and Bouchard, V. and Goldner, E. and Brink, J. and Lang, D. and Kang, S. and Barr, A.M. and Honer, W.G.
DOI: 10.1097/NMD.0000000000000059
2013

Personalized risk assessment of drug-related harm is associated with health outcomes
PLoS ONE
Jones, A.A. and Vila-Rodriguez, F. and Panenka, W.J. and Leonova, O. and Strehlau, V. and Lang, D.J. and Thornton, A.E. and Wong, H. and Barr, A.M. and Procyshyn, R.M. and Smith, G.N. and Buchanan, T. and Krajden, M. and Krausz, M. and Montaner, J.S. and MacEwan, G.W. and Nutt, D.J. and Honer, W.G.
DOI: 10.1371/journal.pone.0079754
2013

Effects of eight weeks of atypical antipsychotic treatment on middle frontal thickness in drug-naïve first-episode psychosis patients
Schizophrenia Research
Goghari, V.M. and Smith, G.N. and Honer, W.G. and Kopala, L.C. and Thornton, A.E. and Su, W. and MacEwan, G.W. and Lang, D.J.
DOI: 10.1016/j.schres.2013.06.025
2013

The hotel study: Multimorbidity in a community sample living in marginal housing
American Journal of Psychiatry
Vila-Rodriguez, F. and Panenka, W.J. and Lang, D.J. and Thornton, A.E. and Vertinsky, T. and Wong, H. and Barr, A.M. and Procyshyn, R.M. and Sidhu, J.J. and Smith, G.N. and Buchanan, T. and Krajden, M. and Krausz, M. and Montaner, J.S. and MacEwan, G.W. and Honer, W.G.
DOI: 10.1176/appi.ajp.2013.12111439
2013

The health benefits and challenges of exercise training in persons living with schizophrenia: A pilot study
Brain Sciences
Bredin, S.S.D. and Warburton, D.E.R. and Lang, D.J.
DOI: 10.3390/brainsci3020821
2013

Antipsychotic medications: Linking receptor antagonism to neuropsychological functioning in first episode psychosis
Journal of the International Neuropsychological Society
Baitz, H.A. and Thornton, A.E. and Procyshyn, R.M. and Smith, G.N. and MacEwan, G.W. and Kopala, L.C. and Barr, A.M. and Lang, D.J. and Honer, W.G.
DOI: 10.1017/S1355617712000343
2012

Short-term stability of T 1 and T 2 relaxation measures in multiple sclerosis normal appearing white matter
Journal of Neurology
Liang, A.L.W. and Vavasour, I.M. and Mädler, B. and Traboulsee, A.L. and Lang, D.J. and Li, D.K.B. and MacKay, A.L. and Laule, C.
DOI: 10.1007/s00415-011-6318-0
2012

Comparison of MERGE and axial T2-weighted fast spin-echo sequences for detection of multiple sclerosis lesions in the cervical spinal cord
American Journal of Roentgenology
Martin, N. and Malfair, D. and Zhao, Y. and Li, D. and Traboulsee, A. and Lang, D. and Vertinsky, A.T.
DOI: 10.2214/AJR.11.7039
2012

White matter tract abnormalities in first-episode psychosis
Schizophrenia Research
Lee, D.Y. and Smith, G.N. and Su, W. and Honer, W.G. and MacEwan, G.W. and Lapointe, J.S. and Vertinsky, A.T. and Vila-Rodriguez, F. and Kopala, L.C. and Lang, D.J.
DOI: 10.1016/j.schres.2012.06.042
2012

Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis
Schizophrenia Research
Smith, G.N. and Thornton, A.E. and Lang, D.J. and MacEwan, G.W. and Ehmann, T.S. and Kopala, L.C. and Tee, K. and Shiau, G. and Voineskos, A.N. and Kennedy, J.L. and Honer, W.G.
DOI: 10.1016/j.schres.2011.11.022
2012

Anterior internal capsule volumes increase in patients with schizophrenia switched from typical antipsychotics to olanzapine
Journal of Psychopharmacology
Goghari, V.M. and Lang, D.J. and Khorram, B. and Götz, J. and Vandorpe, R.A. and Smith, G.N. and Kopala, L.C. and Barr, A.M. and Honer, W.G.
DOI: 10.1177/0269881110363314
2011

The association of elevated body mass index with reduced brain volumes in first-episode mania
Biological Psychiatry
Bond, D.J. and Lang, D.J. and Noronha, M.M. and Kunz, M. and Torres, I.J. and Su, W. and Honer, W.G. and Lam, R.W. and Yatham, L.N.
DOI: 10.1016/j.biopsych.2011.02.025
2011

First episode psychosis with extrapyramidal signs prior to antipsychotic drug treatment
Chinese Science Bulletin
Honer, W.G. and Lang, D.J. and Kopala, L.C. and Macewan, G.W. and Smith, G.N. and Chen, E.Y.H. and Chan, R.C.K.
DOI: 10.1007/s11434-011-4738-y
2011

Prenatal tobacco exposure in first-episode psychosis
Schizophrenia Research
Smith, G.N. and MacEwan, G.W. and Kopala, L.C. and Ehmann, T.S. and Good, K. and Thornton, A.E. and Neilson, H. and Lang, D.J. and Barr, A.M. and Honer, W.G.
DOI: 10.1016/j.schres.2010.01.004
2010

Profiles of individuals seeking psychiatric help for psychotic symptoms linked to methamphetamine abuse - Baseline results from the MAPS (methamphetamine and psychosis study)
Mental Health and Substance Use: Dual Diagnosis
Lecomte, T. and Mueser, K.T. and MacEwan, W.G. and Laferriere-Simard, M.-C. and Thornton, A.E. and Buchanan, T. and Goldner, E. and Brink, J. and Ehmann, T.S. and Lang, D. and Kang, S. and Barr, A.M. and Honer, W.G.
DOI: 10.1080/17523281.2010.504645
2010

Localization of the subthalamic nucleus: Optimization with susceptibility-weighted phase MR imaging
American Journal of Neuroradiology
Vertinsky, A.T. and Coenen, V.A. and Lang, D.J. and Kolind, S. and Honey, C.R. and Li, D. and Rauscher, A.
DOI: 10.3174/ajnr.A1669
2009

Predictors of starting to smoke cigarettes in patients with first episode psychosis
Schizophrenia Research
Smith, G.N. and Wong, H. and MacEwan, G.W. and Kopala, L.C. and Ehmann, T.S. and Thornton, A.E. and Lang, D.J. and Barr, A.M. and Procyshyn, R. and Austin, J.C. and Flynn, S.W. and Honer, W.G.
DOI: 10.1016/j.schres.2008.12.013
2009

A family-based association study of the myelin-associated glycoprotein and 2',3'-cyclic nucleotide 3'-phosphodiesterase genes with schizophrenia
Psychiatric Genetics
Voineskos, A.N. and De Luca, V. and Bulgin, N.L. and Van Adrichem, Q. and Shaikh, S. and Lang, D.J. and Honer, W.G. and Kennedy, J.L.
DOI: 10.1097/YPG.0b013e3282fa1874
2008

MAG gene variation and cortical gray matter volume in first episode schizophrenia
Brain Imaging and Behavior
Voineskos, A.N. and Lang, D.J. and Zai, G. and Bulgin, N. and Shaikh, S. and Su, W. and Kopala, L.C. and MacEwan, G.W. and Thornton, A.E. and Smith, G.N. and Austin, J.C. and Honer, W.G. and Kennedy, J.L.
DOI: 10.1007/s11682-008-9023-6
2008

A longitudinal study on the effects of typical versus atypical antipsychotic drugs on hippocampal volume in schizophrenia
Schizophrenia Research
Panenka, W.J. and Khorram, B. and Barr, A.M. and Smith, G.N. and Lang, D.J. and Kopala, L.C. and Vandorpe, R.A. and Honer, W.G.
DOI: 10.1016/j.schres.2007.05.002
2007

The need for speed: An update on methamphetamine addiction.
Journal of Psychiatry & Neuroscience
09/2006

Reduced anterior internal capsule and thalamic volumes in first-episode psychosis
Schizophrenia Research
Lang, D.J. and Khorram, B. and Goghari, V.M. and Kopala, L.C. and Vandorpe, R.A. and Rui, Q. and Smith, G.N. and Honer, W.G.
DOI: 10.1016/j.schres.2006.05.002
2006

Lateral asymmetry in the shape of brain ventricles in control and schizophrenia groups
2006 3rd IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings
Graham, J. and Babalola, K.O. and Honer, W.G. and Lang, D. and Kopala, L. and Vandorpe, R.
2006

The need for speed: An update on methamphetamine addiction
Journal of Psychiatry and Neuroscience
Barr, A.M. and Panenka, W.J. and MacEwan, G.W. and Thornton, A.E. and Lang, D.J. and Honer, W.G. and Lecomte, T.
2006

Reduced thalamic volume in patients with chronic schizophrenia after switching from typical antipsychotic medications to olanzapine
American Journal of Psychiatry
Khorram, B. and Lang, D.J. and Kopala, L.C. and Vandorpe, R.A. and Rui, Q. and Goghari, V.M. and Smith, G.N. and Honer, W.G.
DOI: 10.1176/ajp.2006.163.11.2005
2006

Smaller corpus callosum subregions containing motor fibers in schizophrenia
Schizophrenia Research
Goghari, V.M. and Lang, D.J. and Flynn, S.W. and MacKay, A.L. and Honer, W.G.
DOI: 10.1016/j.schres.2004.08.023
2005

The genetic and environmental basis of the relationship between schizotypy and personality: A twin study
Journal of Nervous and Mental Disease
Jang, K.L. and Woodward, T.S. and Lang, D. and Honer, W.G. and Livesley, W.J.
DOI: 10.1097/01.nmd.0000154842.26600.bd
2005

Reduced basal ganglia volumes after switching to olanzapine in chronically treated patients with schizophrenia
American Journal of Psychiatry
Lang, D.J. and Kopala, L.C. and Vandorpe, R.A. and Rui, Q. and Smith, G.N. and Goghari, V.M. and Lapointe, J.S. and Honer, W.G.
DOI: 10.1176/ajp.161.10.1829
2004

An investigation of morphometric changes in the lateral ventricles of schizophrenic subjects
Lecture Notes in Computer Science
Babalola, K. and Graham, J. and Honer, W. and Kopala, L. and Lang, D. and Vandorpe, R.
DOI: 10.1007/978-3-540-39903-2_64
2003

Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins
Molecular Psychiatry
Flynn, S.W. and Lang, D.J. and Mackay, A.L. and Goghari, V. and Vavasour, I.M. and Whittall, K.P. and Smith, G.N. and Arango, V. and Mann, J.J. and Dwork, A.J. and Falkai, P. and Honer, W.G.
DOI: 10.1038/sj.mp.4001337
2003

Developmental abnormalities of the hippocampus in first-episode schizophrenia
Biological Psychiatry
Smith, G.N. and Lang, D.J. and Kopala, L.C. and Lapointe, J.S. and Falkai, P. and Honer, W.G.
DOI: 10.1016/S0006-3223(02)01977-7
2003

An MRI study of basal ganglia volumes in first-episode schizophrenia patients treated with risperidone
American Journal of Psychiatry
Lang, D.J. and Kopala, L.C. and Vandorpe, R.A. and Rui, Q. and Smith, G.N. and Goghari, V.M. and Honer, W.G.
DOI: 10.1176/appi.ajp.158.4.625
2001

No evidence for linkage of the CHRNA7 gene region in Canadian schizophrenia families
American Journal of Medical Genetics - Neuropsychiatric Genetics
Neves-Pereira, M. and Bassett, A.S. and Honer, W.G. and Lang, D. and King, N.A. and Kennedy, J.L.
DOI: 10.1002/(SICI)1096-8628(19980907)81:53.0.CO;2-W
1998

Sylvian fissure and middle cranial fossae asymmetries in families with schizophrenia
Schizophrenia Research
Donna J. Lang and Anne S. Bassett and Peter Falkai and Geoffrey N. Smith and Jocelyne S. Lapointe and William G. Honer
DOI: 10.1016/s0920-9964(97)82429-2
01/1997

The temporal lobes, reversed asymmetry and the genetics of schizophrenia
NeuroReport
Honer, W.G. and Bassett, A.S. and Squires-Wheeler, E. and Falkai, P. and Smith, G.N. and Lapointe, J.S. and Canero, C. and Lang, D.J.
DOI: 10.1097/00001756-199512290-00053
1995

Research
Research Group Members

Ava Grier, Masters Student