- Overview
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Steroid hormones control a wide range of normal biological processes but are also implicated in several disease processes including reproductive disorders, inflammation, diabetes, cardiovascular disease, and hormone-dependent cancers of male and female reproductive tissues. Synthetic steroids that act as agonists or antagonists are used widely as pharmacologic agents. The way steroids gain access to their target tissues is poorly understood. However, access is influenced primarily by two high affinity steroid-binding proteins in the blood: corticosteroid binding globulin (CBG) and sex hormone-binding globulin (SHBG). These two plasma proteins bind the glucocorticoids and sex steroids, respectively. By applying a combination of molecular biological, biochemical and physiological approaches we have gained new information about how CBG and SHBG are produced and function with respect to normal development and aging, and how they are involved in disease processes.
- Publications
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Evolution of sex hormone-binding globulin gene expression in the primate testis
bioRxiv
DOI: 10.1101/2024.08.05.606716
2024Corticosteroid-Binding Globulin (SERPINA6) Consolidates Sexual Dimorphism of Adult Rat Liver
Endocrinology (United States)
DOI: 10.1210/endocr/bqad179
2024Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin
FEBS Open Bio
Anne Mette Frøbert and Malene Brohus and Julia N. C. Toews and Phillip Round and Ole Fröbert and Geoffrey L. Hammond and Michael T. Overgaard
DOI: 10.1002/2211-5463.13341
02/2022Corticosteroid-binding Globulin (SERPINA6) Establishes Postpubertal Sex Differences in Rat Adrenal Development
Endocrinology (United States)
Toews, J.N.C. and Philippe, T.J. and Hill, L.A. and Dordevic, M. and Miguelez-Crespo, A. and Homer, N.Z.M. and Nixon, M. and Hammond, G.L. and Viau, V.
DOI: 10.1210/endocr/bqac152
2022Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats
Physiological and Biochemical Zoology
Fr?bert, A.M. and Toews, J.N.C. and Nielsen, C.G. and Brohus, M. and Kindberg, J. and Jessen, N. and Fr{\"o}bert, O. and Hammond, G.L. and Overgaard, M.T.
DOI: 10.1086/721154
2022Homozygous SHBG Variant (rs6258) Linked to Gonadotropin-Independent Precocious Puberty in a Young Girl
Journal of the Endocrine Society
Victoria C Andriessen and Marissa Lightbourne and Chelsi Flippo and Fabio R Faucz and Angela Delaney and Fady Hannah-Shmouni and Geoffrey L Hammond and Constantine A Stratakis
DOI: 10.1210/jendso/bvab125
10/2021Liver at the nexus of rat postnatal HPA axis maturation and sexual dimorphism.
The Journal of endocrinology
Toews JNC and Hammond GL and Viau V
DOI: 10.1530/joe-20-0286
PubMed: 33112814
01/2021Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally-Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): A Healthy Life Trajectories Initiative (HeLTI) Study
BMJ Open
Kumaran, K. and Krishnaveni, G.V. and Suryanarayana, K.G. and Prasad, M.P. and Belavendra, A. and Atkinson, S. and Balasubramaniam, R. and Bandsma, R.H.J. and Bhutta, Z.A. and Chandak, G.R. and Comelli, E.M. and Davidge, S.T. and Dennis, C.-L. and Hammond, G.L. and Jha, P. and Joseph, K.S. and Joshi, S.R. and Krishna, M. and Lee, K. and Lye, S. and McGowan, P. and Nepomnaschy, P. and Padvetnaya, V. and Pyne, S. and Sachdev, H.S. and Sahariah, S.A. and Singhal, N. and Trasler, J. and Yajnik, C.S. and Baird, J. and Barker, M. and Martin, M.-C. and Husain, N. and Sellen, D. and Fall, C.H.D. and Shah, P.S. and Matthews, S.G.
DOI: 10.1136/bmjopen-2020-045862
2021Spotted hyaenas and the sexual spectrum: reproductive endocrinology and development.
The Journal of endocrinology
Conley A and Place NJ and Legacki EL and Hammond GL and Cunha GR and Drea CM and Weldele ML and Glickman SE
DOI: 10.1530/joe-20-0252
PubMed: 32755997
10/2020SUN-221 Subclinical Alpha-1 Antitrypsin Deficiency Is Associated with Increased Free Cortisol Fraction in Plasma and Altered Glucocorticoid Delivery to Tissues.
Journal of the Endocrine Society
Boyle LD and Nixon M and Underhill CM and Hill LA and Homer NZM and Andrew R and Hammond GL and Lewis JG and Stimson RH and Walker BR
05/2020Molecular interactions between sex hormone–binding globulin and nonsteroidal ligands that enhance androgen activity
Journal of Biological Chemistry
Phillip Round and Samir Das and Tsung-Sheng Wu and Kristiina Wähälä and Filip Van Petegem and Geoffrey L. Hammond
DOI: 10.1016/S0021-9258(17)49880-2
01/2020Molecular interactions between sex hormone– binding globulin and nonsteroidal ligands that enhance androgen activity
Journal of Biological Chemistry
Round, P. and Das, S. and Wu, T.-S. and Wähälä, K. and van Petegem, F. and Hammond, G.L.
DOI: 10.1074/jbc.RA119.011051
2020STEROIDS IN NORMAL AND DISEASED HUMAN PROSTATIC TISSUE
Hormones in Normal and Abnormal Human Tissues: Volume 1
DOI: 10.1515/9783111447001-023
2019Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression
Archives of Women's Mental Health
Pawluski, J.L. and Brain, U. and Hammond, G.L. and Oberlander, T.F.
DOI: 10.1007/s00737-018-0931-1
2019Sex hormone binding globulin during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis)
General and Comparative Endocrinology
González, A. and Fernandino, J.I. and Elisio, M. and Chalde, T. and Miranda, L.A. and Hammond, G.L. and Somoza, G.M.
DOI: 10.1016/j.ygcen.2018.11.010
2019N-glycosylation influences human corticosteroid-binding globulin measurements
Endocrine Connections
Hill, L.A. and Sumer-Bayraktar, Z. and Lewis, J.G. and Morava, E. and Thaysen-Andersen, M. and Hammond, G.L.
DOI: 10.1530/EC-19-0242
2019Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam
Behavioural Brain Research
Gemmel, M. and Harmeyer, D. and Bögi, E. and Fillet, M. and Hill, L.A. and Hammond, G.L. and Charlier, T.D. and Pawluski, J.L.
DOI: 10.1016/j.bbr.2017.11.038
2018Roles of plasma binding proteins in modulation of hormone action and metabolism
Encyclopedia of Endocrine Diseases
DOI: 10.1016/B978-0-12-801238-3.64186-7
2018Human sex hormone-binding globulin does not provide metabolic protection against diet-induced obesity and dysglycemia in mice
Endocrine Connections
Sofer, Y. and Nevo, N. and Vechoropoulos, M. and Shefer, G. and Osher, E. and Landis, N. and Tordjman, K. and Hammond, G.L. and Stern, N.
DOI: 10.1530/EC-17-0240
2018The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester
BMC Medicine
Johnston, Z.C. and Bellingham, M. and Filis, P. and Soffientini, U. and Hough, D. and Bhattacharya, S. and Simard, M. and Hammond, G.L. and King, P. and O'Shaughnessy, P.J. and Fowler, P.A.
DOI: 10.1186/s12916-018-1009-7
2018Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma
Journal of Endocrinology
Hill, L.A. and Vassiliadi, D.A. and Dimopoulou, I. and Anderson, A.J. and Boyle, L.D. and Kilgour, A.H.M. and Stimson, R.H. and Machado, Y. and Overall, C.M. and Walker, B.R. and Lewis, J.G. and Hammond, G.L.
DOI: 10.1530/JOE-18-0479
2018Erratum: Author Correction: Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox (Scientific reports (2017) 7 1 (12284))
Scientific reports
Saez-Lopez, C. and Brianso-Llort, L. and Torres-Torronteras, J. and Simó, R. and Hammond, G.L. and Selva, D.M.
DOI: 10.1038/s41598-018-23159-y
2018Functional implications of corticosteroid-binding globulin N-glycosylation
Journal of Molecular Endocrinology
Simard, M. and Underhill, C. and Hammond, G.L.
DOI: 10.1530/JME-17-0234
2018Neutrophil elastase-mediated regulation of adipose glucocorticoid exposure through CBG cleavage
Endocrine Abstracts
Mark Nixon and Lesley Hill and Caroline Underhill and Geoffrey Hammond and Brian Walker
DOI: 10.1530/endoabs.50.oc3.4
10/2017Long-Term Consequences of Extended Endocrine Strategies for Premenopausal Breast Cancer [11OP]
Obstetrics & Gynecology
Janice S. Kwon and Gary Pansegrau and Melica Nourmoussavi and Geoffrey Hammond and Mark Carey
DOI: 10.1097/01.aog.0000513940.92490.68
05/2017Sex hormone binding globulin: Expression throughout early development and adult pejerrey fish, Odontesthes bonariensis
General and Comparative Endocrinology
González, A. and Fernandino, J.I. and Hammond, G.L. and Somoza, G.M.
DOI: 10.1016/j.ygcen.2017.02.004
2017Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: A new Contribution to the French Paradox
Scientific Reports
Saez-Lopez, C. and Brianso-Llort, L. and Torres-Torrenteras, J. and Simó, R. and Hammond, G.L. and Selva, D.M.
DOI: 10.1038/s41598-017-12509-x
2017Costs and benefits of extended endocrine strategies for premenopausal breast cancer
JNCCN Journal of the National Comprehensive Cancer Network
Kwon, J.S. and Pansegrau, G. and Nourmoussavi, M. and Hammond, G.L. and Carey, M.S.
DOI: 10.6004/jnccn.2017.0136
2017Sex hormone-binding globulin and the metabolic syndrome
Contemporary Endocrinology
DOI: 10.1007/978-3-319-53298-1_15
2017Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress
Psychoneuroendocrinology
Gemmel, M. and Hazlett, M. and Bögi, E. and De Lacalle, S. and Hill, L.A. and Kokras, N. and Hammond, G.L. and Dalla, C. and Charlier, T.D. and Pawluski, J.L.
DOI: 10.1016/j.psyneuen.2017.07.480
2017Ovarian ablation for premenopausal breast cancer: A review of treatment considerations and the impact of premature menopause
Cancer Treatment Reviews
Nourmoussavi, M. and Pansegrau, G. and Popesku, J. and Hammond, G.L. and Kwon, J.S. and Carey, M.S.
DOI: 10.1016/j.ctrv.2017.02.005
2017Control of androgen bioactivity by sex hormone-binding globulin
Endocrine Abstracts
Michael R Laurent and Leen Antonio and Marco H Blokland and Saskia S Sterk and Ferran Jardi and V Dubois and Jean-Mark Kaufman and Tom Fiers and Ilpo T Huhtaniemi and Geoffrey T. Hammond and Dirk Vanderschueren and Frank Claessens
DOI: 10.1530/endoabs.42.oc2
09/2016Corticosteroid-binding globulin is a biomarker of inflammation onset and severity in female rats
Journal of Endocrinology
Hill, L.A. and Bodnar, T.S. and Weinberg, J. and Hammond, G.L.
DOI: 10.1530/JOE-16-0047
2016Plasma steroid-binding proteins: Primary gatekeepers of steroid hormone action
Journal of Endocrinology
Hammond, G.L.
DOI: 10.1530/JOE-16-0070
2016Effects of sex hormone-binding globulin (SHBG) on androgen bioactivity in vitro
Molecular and Cellular Endocrinology
Laurent, M.R. and Helsen, C. and Antonio, L. and Schollaert, D. and Joniau, S. and Vos, M.J. and Decallonne, B. and Hammond, G.L. and Vanderschueren, D. and Claessens, F.
DOI: 10.1016/j.mce.2016.08.041
2016Long-term consequences of ovarian ablation for premenopausal breast cancer
Breast Cancer Research and Treatment
Kwon, J.S. and Pansegrau, G. and Nourmoussavi, M. and Hammond, G. and Carey, M.S.
DOI: 10.1007/s10549-016-3842-8
2016Identification of avian corticosteroid-binding globulin (SerpinA6) reveals the molecular basis of evolutionary adaptations in SerpinA6 structure and function as a steroid-binding protein
Journal of Biological Chemistry
Vashchenko, G. and Das, S. and Moon, K.-M. and Rogalski, J.C. and Taves, M.D. and Soma, K.K. and Van Petegem, F. and Foster, L.J. and Hammond, G.L.
DOI: 10.1074/jbc.M116.714378
2016Sex hormone-binding globulin regulation of androgen bioactivity in vivo: Validation of the free hormone hypothesis
Scientific Reports
Laurent, M.R. and Hammond, G.L. and Blokland, M. and Jardí, F. and Antonio, L. and Dubois, V. and Khalil, R. and Sterk, S.S. and Gielen, E. and Decallonne, B. and Carmeliet, G. and Kaufman, J.-M. and Fiers, T. and Huhtaniemi, I.T. and Vanderschueren, D. and Claessens, F.
DOI: 10.1038/srep35539
2016Controlling the freedom of steroids in health and disease
Endocrine Abstracts
Geoffrey Hammond
DOI: 10.1530/endoabs.38.pl9
10/2015Plasma corticosteroid-binding globulin: biomarker of inflammation onset and severity in a rat arthritis model
Endocrine Abstracts
Lesley Hill and Tamara Bodner and Joanne Weinberg and Geoffrey Hammond
DOI: 10.1530/endoabs.38.p387
10/2015Society for Endocrinology International Medal Lecture
Endocrine Abstracts
Geoffrey Hammond
DOI: 10.1530/endoabs.38.pl9biog
10/2015Naturally occurring mutations of human corticosteroid-binding globulin
Journal of Clinical Endocrinology and Metabolism
Simard, M. and Hill, L.A. and Lewis, J.G. and Hammond, G.L.
DOI: 10.1210/jc.2014-3130
2015Colony-specific differences in endocrine and immune responses to an inflammatory challenge in female Sprague Dawley rats
Endocrinology
Bodnar, T.S. and Hill, L.A. and Taves, M.D. and Yu, W. and Soma, K.K. and Hammond, G.L. and Weinberg, J.
DOI: 10.1210/en.2015-1497
2015Somatostatin is essential for the sexual dimorphism of gh secretion, corticosteroid-binding globulin production, and corticosterone levels in mice
Endocrinology
Adams, J.M. and Otero-Corchon, V. and Hammond, G.L. and Veldhuis, J.D. and Qi, N. and Low, M.J.
DOI: 10.1210/en.2014-1429
2015Impact of corticosteroid-binding globulin deficiency on pregnancy and neonatal sex
Journal of Clinical Endocrinology and Metabolism
Lei, J.-H. and Yang, X. and Peng, S. and Li, Y. and Underhill, C. and Zhu, C. and Lin, H.-Y. and Wang, H. and Hammond, G.L.
DOI: 10.1210/jc.2014-4254
2015Pseudomonas aeruginosa elastase disrupts the cortisol-binding activity of corticosteroid-binding globulin
Endocrinology
Simard, M. and Hill, L.A. and Underhill, C.M. and Keller, B.O. and Villanueva, I. and Hancock, R.E.W. and Hammond, G.L.
DOI: 10.1210/en.2014-1055
2014Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin
PLoS Genetics
Bolton, J.L. and Hayward, C. and Direk, N. and Lewis, J.G. and Hammond, G.L. and Hill, L.A. and Anderson, A. and Huffman, J. and Wilson, J.F. and Campbell, H. and Rudan, I. and Wright, A. and Hastie, N. and Wild, S.H. and Velders, F.P. and Hofman, A. and Uitterlinden, A.G. and Lahti, J. and Räikkönen, K. and Kajantie, E. and Widen, E. and Palotie, A. and Eriksson, J.G. and Kaakinen, M. and Järvelin, M.-R. and Timpson, N.J. and Davey Smith, G. and Ring, S.M. and Evans, D.M. and St Pourcain, B. and Tanaka, T. and Milaneschi, Y. and Bandinelli, S. and Ferrucci, L. and van der Harst, P. and Rosmalen, J.G.M. and Bakker, S.J.L. and Verweij, N. and Dullaart, R.P.F. and Mahajan, A. and Lindgren, C.M. and Morris, A. and Lind, L. and Ingelsson, E. and Anderson, L.N. and Pennell, C.E. and Lye, S.J. and Matthews, S.G. and Eriksson, J. and Mellstrom, D. and Ohlsson, C. and Price, J.F. and Strachan, M.W.J. and Reynolds, R.M. and Tiemeier, H. and Walker, B.R.
DOI: 10.1371/journal.pgen.1004474
2014Naturally occurring mutants inform SHBG structure and function
Molecular Endocrinology
Wu, T.-S. and Hammond, G.L.
DOI: 10.1210/me.2014-1058
2014Development of the external genitalia: Perspectives from the spotted hyena (Crocuta crocuta)
Differentiation
Cunha, G.R. and Risbridger, G. and Wang, H. and Place, N.J. and Grumbach, M. and Cunha, T.J. and Weldele, M. and Conley, A.J. and Barcellos, D. and Agarwal, S. and Bhargava, A. and Drea, C. and Hammond, G.L. and Siiteri, P. and Coscia, E.M. and McPhaul, M.J. and Baskin, L.S. and Glickman, S.E.
DOI: 10.1016/j.diff.2013.12.003
2014Evolving utility of sex hormone-binding globulin measurements in clinical medicine
Current Opinion in Endocrinology, Diabetes and Obesity
Hammond, G.L. and Wu, T.-S. and Simard, M.
DOI: 10.1097/MED.0b013e328353732f
2012Ontogenesis of phase i hepatic drug metabolic enzymes in sheep
Reproduction, Fertility and Development
Pretheeban, M. and Hammond, G. and Bandiera, S. and Riggs, W. and Rurak, D.
DOI: 10.1071/RD11159
2012Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
PLoS ONE
Gardill, B.R. and Vogl, M.R. and Lin, H.-Y. and Hammond, G.L. and Muller, Y.A.
DOI: 10.1371/journal.pone.0052759
2012Two different corticosteroid-binding globulin variants that lack cortisol-binding activity in a Greek woman
Journal of Clinical Endocrinology and Metabolism
Hill, L.A. and Vassiliadi, D.A. and Simard, M. and Pavlaki, A. and Perogamvros, I. and Hadjidakis, D. and Hammond, G.L.
DOI: 10.1210/jc.2012-2467
2012Rhox5 rules in an evolving saga of reproductive diversity.
Biology of reproduction
Hammond, G.L.
DOI: 10.1095/biolreprod.112.101402
2012Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function
Psychoneuroendocrinology
Pawluski, J.L. and Brain, U.M. and Underhill, C.M. and Hammond, G.L. and Oberlander, T.F.
DOI: 10.1016/j.psyneuen.2011.11.011
2012Phylogenetic comparisons implicate sex hormone-binding globulin in "masculinization" of the female spotted hyena (Crocuta crocuta)
Endocrinology
Hammond, G.L. and Miguel-Queralt, S. and Yalcinkaya, T.M. and Underhill, C. and Place, N.J. and Glickman, S.E. and Drea, C.M. and Wagner, A.P. and Siiteri, P.K.
DOI: 10.1210/en.2011-1837
2012High frequency of SERPINA6 polymorphisms that reduce plasma corticosteroid-binding globulin activity in Chinese subjects
Journal of Clinical Endocrinology and Metabolism
Lin, H.-Y. and Underhill, C. and Lei, J.-H. and Helander-Claesson, A. and Lee, H.-Y. and Gardill, B.R. and Muller, Y.A. and Wang, H. and Hammond, G.L.
DOI: 10.1210/jc.2011-3141
2012Serum free estradiol and estrogen receptor-a mediated activity are related to decreased incident hip fractures in older women
Bone
Lim, V.W. and Li, J. and Gong, Y. and Yuan, J.-M. and Wu, T.S. and Hammond, G.L. and Jin, A. and Koh, W.-P. and Yong, E.L.
DOI: 10.1016/j.bone.2012.03.006
2012Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells
Endocrinology
Sanchez, W.Y. and De Veer, S.J. and Swedberg, J.E. and Hong, E.-J. and Reid, J.C. and Walsh, T.P. and Hooper, J.D. and Hammond, G.L. and Clements, J.A. and Harris, J.M.
DOI: 10.1210/en.2012-1011
2012Fathead Minnow Sex Hormone-binding Globulin as Tool for Ecotoxicology Assessment.
Biology of Reproduction
Jason T. Popesku and Vicki L. Marlatt and Geoffrey L. Hammond
DOI: 10.1093/biolreprod/85.s1.289
07/2011FoxA2 Mediates Monosaccharide-Induced Repression of SHBG Gene Expression by Regulating Lipid Homeostasis in HepG2 Cells.
Biology of Reproduction
Tsung-Sheng Wu and Geoffrey L. Hammond
DOI: 10.1093/biolreprod/85.s1.622
07/2011When an Egg Is Not an Egg: Compromised Maternal mRNA Storage and Stabilization
Biology of Reproduction
M. Conti
DOI: 10.1095/biolreprod.111.094102
06/201137-kDa Laminin Receptor Precursor Mediates GnRH-II–Induced MMP-2 Expression and Invasiveness in Ovarian Cancer Cells
Molecular Endocrinology
Song Ling Poon and Christian Klausen and Geoffrey L. Hammond and Peter C. K. Leung
DOI: 10.1210/me.2010-0334
02/2011(Arene)Cl
2 Ru(II) complexes with N-coordinated estrogen and androgen isonicotinates: Interaction with sex hormone binding globulin and anticancer activity
Steroids
Schobert, R. and Seibt, S. and Effenberger-Neidnicht, K. and Underhill, C. and Biersack, B. and Hammond, G.L.
DOI: 10.1016/j.steroids.2010.12.009
2011Diverse roles for sex hormone-binding globulin in reproduction
Biology of Reproduction
Hammond, G.L.
DOI: 10.1095/biolreprod.111.092593
2011Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via ß-catenin signaling in ovarian cancer cells
Endocrinology
Poon, S.L. and Lau, M.-T. and Hammond, G.L. and Leung, P.C.K.
DOI: 10.1210/en.2010-0942
2011Genetic determinants of serum testosterone concentrations in men
PLoS Genetics
Ohlsson, C. and Wallaschofski, H. and Lunetta, K.L. and Stolk, L. and Perry, J.R.B. and Koster, A. and Petersen, A.-K. and Eriksson, J. and Lehtimäki, T. and Huhtaniemi, I.T. and Hammond, G.L. and Maggio, M. and Coviello, A.D. and Emas Study Group and Ferrucci, L. and Heier, M. and Hofman, A. and Holliday, K.L. and Jansson, J.-O. and Kähönen, M. and Karasik, D. and Karlsson, M.K. and Kiel, D.P. and Liu, Y. and Ljunggren, O. and Lorentzon, M. and Lyytikäinen, L.-P. and Meitinger, T. and Mellström, D. and Melzer, D. and Miljkovic, I. and Nauck, M. and Nilsson, M. and Penninx, B. and Pye, S.R. and Vasan, R.S. and Reincke, M. and Rivadeneira, F. and Tajar, A. and Teumer, A. and Uitterlinden, A.G. and Ulloor, J. and Viikari, J. and Völker, U. and Völzke, H. and Wichmann, H.E. and Wu, T.-S. and Zhuang, W.V. and Ziv, E. and Wu, F.C.W. and Raitakari, O. and Eriksson, A. and Bidlingmaier, M. and Harris, T.B. and Murray, A. and de Jong, F.H. and Murabito, J.M. and Bhasin, S. and Vandenput, L. and Haring, R.
DOI: 10.1371/journal.pgen.1002313
2011Ontogenesis of UDP-glucuronosyltransferase enzymes in sheep
Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology
Pretheeban, M. and Hammond, G. and Bandiera, S. and Riggs, W. and Rurak, D.
DOI: 10.1016/j.cbpa.2011.02.014
2011Cytoplasmic accumulation of incompletely glycosylated shbg enhances androgen action in proximal tubule epithelial cells
Molecular Endocrinology
Hong, E.-J. and Sahu, B. and Jänne, O.A. and Hammond, G.L.
DOI: 10.1210/me.2010-0483
2011Molecular and Cellular Endocrinology. Foreward.
Molecular and cellular endocrinology
Hammond, G.L.
2010Molecular and structural basis of steroid hormone binding and release from corticosteroid-binding globulin
Molecular and Cellular Endocrinology
Lin, H.-Y. and Muller, Y.A. and Hammond, G.L.
DOI: 10.1016/j.mce.2009.06.015
2010Gonadotropin-releasing hormone-I-mediated activation of progesterone receptor contributes to gonadotropin a-subunit expression in mouse gonadotrophs
Endocrinology
Chen, J. and An, B.-S. and So, W.-K. and Cheng, L. and Hammond, G.L. and Leung, P.C.K.
DOI: 10.1210/en.2009-0816
2010Foreward
Molecular and Cellular Endocrinology
Hammond, G.L.
DOI: 10.1016/j.mce.2009.09.015
2010Structural analyses of sex hormone-binding globulin reveal novel ligands and function
Molecular and Cellular Endocrinology
Avvakumov, G.V. and Cherkasov, A. and Muller, Y.A. and Hammond, G.L.
DOI: 10.1016/j.mce.2009.09.005
2010Novel corticosteroid-binding globulin variant that lacks steroid binding activity
Journal of Clinical Endocrinology and Metabolism
Perogamvros, I. and Underhill, C. and Henley, D.E. and Hadfield, K.D. and Newman, W.G. and Ray, D.W. and Lightman, S.L. and Hammond, G.L. and Trainer, P.J.
DOI: 10.1210/jc.2010-0746
2010In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin
Toxicology and Applied Pharmacology
Thorsteinson, N. and Ban, F. and Santos-Filho, O. and Tabaei, S.M.H. and Miguel-Queralt, S. and Underhill, C. and Cherkasov, A. and Hammond, G.L.
DOI: 10.1016/j.taap.2008.07.014
2009Effects of aggressive encounters on plasma corticosteroid-binding globulin and its ligands in white-crowned sparrows
Hormones and Behavior
Charlier, T.D. and Underhill, C. and Hammond, G.L. and Soma, K.K.
DOI: 10.1016/j.yhbeh.2009.06.012
2009Characterization and Measurement of the Plasma a- and ß-Sex Hormone-Binding Globulin Paralogs in Salmon
Endocrinology
Miguel-Queralt, S. and Underhill, C. and Devlin, R.H. and Hammond, G.L.
DOI: 10.1210/en.2008-0964
2009Thyroid hormones act indirectly to increase sex hormone-binding globulin production by liver via hepatocyte nuclear factor-4a
Journal of Molecular Endocrinology
Selva, D.M. and Hammond, G.L.
DOI: 10.1677/JME-09-0025
2009Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-a contributes to fosB expression in mouse gonadotrophs
Endocrinology
Chen, J. and An, B.-S. and Cheng, L. and Hammond, G.L. and Leung, P.C.K.
DOI: 10.1210/en.2009-0455
2009Reproductive experience alters corticosterone and CBG levels in the rat dam
Physiology and Behavior
Pawluski, J.L. and Charlier, T.D. and Lieblich, S.E. and Hammond, G.L. and Galea, L.A.M.
DOI: 10.1016/j.physbeh.2008.09.004
2009Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor
Biology of Reproduction
An, B.-S. and Song, L.P. and So, W.-K. and Hammond, G.L. and Leung, P.C.K.
DOI: 10.1095/biolreprod.109.076216
2009Residues in the human corticosteroid-binding globulin reactive center loop that influence steroid binding before and after elastase cleavage
Journal of Biological Chemistry
Lin, H.-Y. and Underhill, C. and Gardill, B.R. and Muller, Y.A. and Hammond, G.L.
DOI: 10.1074/jbc.M807376200
2009Peroxisome-proliferator receptor ¿ represses hepatic sex hormone-binding globulin expression
Endocrinology
Hammond, G.L. and Selva, D.M.
DOI: 10.1210/en.2008-1289
2009Two Forms of Sex Hormone-Binding Globulin in Salmonid Blood.
Biology of Reproduction
Solange Miguel-Queralt and Caroline Underhill and Geoffrey L. Hammond
DOI: 10.1093/biolreprod/78.s1.215c
05/2008Estetrol does not bind sex hormone binding globulin or increase its production by human HepG2 cells
Climacteric
Hammond, G.L. and Hogeveen, K.N. and Visser, M. and Coelingh Bennink, H.J.T.
DOI: 10.1080/13697130701851814
2008Estrogen receptor a gene polymorphisms are associated with idiopathic premature ovarian failure
Fertility and Sterility
Bretherick, K.L. and Hanna, C.W. and Currie, L.M. and Fluker, M.R. and Hammond, G.L. and Robinson, W.P.
DOI: 10.1016/j.fertnstert.2007.03.008
2008Sex hormone-binding globulin in fish gills is a portal for sex steroids breached by xenobiotics
Endocrinology
Miguel-Queralt, S. and Hammond, G.L.
DOI: 10.1210/en.2008-0384
2008An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin
Journal of Medicinal Chemistry
Cherkasov, A. and Ban, F. and Santos-Filho, O. and Thorsteinson, N. and Fallahi, M. and Hammond, G.L.
DOI: 10.1021/jm7011485
2008Temporal recruitment of transcription factors at the 3',5'- cyclic adenosine 5'-monophosphate-response element of the human GnRH-II promoter
Endocrinology
Song, L.P. and An, B.-S. and So, W.-K. and Hammond, G.L. and Leung, P.C.K.
DOI: 10.1210/en.2008-0481
2008Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene
Journal of Clinical Investigation
Selva, D.M. and Hogeveen, K.N. and Innis, S.M. and Hammond, G.L.
DOI: 10.1172/JCI32249
2007Steroid conjugates of dichloro(6-aminomethylnicotinate) platinum(II): Effects on DNA, sex hormone binding globulin, the estrogen receptor, and various breast cancer cell lines
ChemMedChem
Schobert, R. and Bernhardt, G. and Biersack, B. and Bollwein, S. and Fallahi, M. and Grotemeierd, A. and Hammond, G.L.
DOI: 10.1002/cmdc.200600173
2007Testicular degeneration in Huntington disease
Neurobiology of Disease
Van Raamsdonk, J.M. and Murphy, Z. and Selva, D.M. and Hamidizadeh, R. and Pearson, J. and Petersén, ?. and Björkqvist, M. and Muir, C. and Mackenzie, I.R. and Hammond, G.L. and Vogl, A.W. and Hayden, M.R. and Leavitt, B.R.
DOI: 10.1016/j.nbd.2007.01.006
2007Corticosteroid-binding Globulin, a Structural Basis for Steroid Transport and Proteinase-triggered Release
Journal of Biological Chemistry
Klieber, M.A. and Underhill, C. and Hammond, G.L. and Muller, Y.A.
DOI: 10.1074/jbc.M705014200
2007Sex hormone-binding globulin expression in sea bass (Dicentrarchus labrax L.) throughout development and the reproductive season
Molecular and Cellular Endocrinology
Miguel-Queralt, S. and Blázquez, M. and Piferrer, F. and Hammond, G.L.
DOI: 10.1016/j.mce.2007.06.009
2007Human Sex Hormone-binding Globulin is Expressed in Testicular Germ Cells and not in Sertoli Cells
Hormone and Metabolic Research
D. Selva and G. Hammond
DOI: 10.1055/s-2006-925336
04/2006Do oral contraceptives produce irreversible effects on women's sexuality? [1]
Journal of Sexual Medicine
Bancroft, J. and Hammond, G. and Graham, C.
DOI: 10.1111/j.1743-6109.2006.00253.x
2006Evidence that fibulin family members contribute to the steroid-dependent extravascular sequestration of sex hormone-binding globulin
Journal of Biological Chemistry
Ng, K.-M. and Catalano, M.G. and Pinós, T. and Selva, D.M. and Avvakumov, G.V. and Munell, F. and Hammond, G.L.
DOI: 10.1074/jbc.M512370200
2006SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density
Journal of Clinical Endocrinology and Metabolism
Eriksson, A.L. and Lorentzon, M. and Mellström, D. and Vandenput, L. and Swanson, C. and Andersson, N. and Hammond, G.L. and Jakobsson, J. and Rane, A. and Orwoll, E.S. and Ljunggren, Ö. and Johnell, O. and Labrie, F. and Windahl, S.H. and Ohlsson, C.
DOI: 10.1210/jc.2006-0679
2006Progressive docking: A hybrid QSAR/docking approach for accelerating in silico high throughput screening
Journal of Medicinal Chemistry
Cherkasov, A. and Ban, F. and Li, Y. and Fallahi, M. and Hammond, G.L.
DOI: 10.1021/jm060961+
2006Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells
Journal of Biological Chemistry
An, B.-S. and Selva, D.M. and Hammond, G.L. and Rivero-Muller, A. and Rahman, N. and Leung, P.C.K.
DOI: 10.1074/jbc.M600743200
2006Human sperm sex hormone-binding globulin isoform: Characterization and measurement by time-resolved fluorescence immunoassay
Journal of Clinical Endocrinology and Metabolism
Selva, D.M. and Bassas, L. and Munell, F. and Mata, A. and Tekpetey, F. and Lewis, J.G. and Hammond, G.L.
DOI: 10.1210/jc.2005-1192
2005Successful in silico discovery of novel nonsteroidal ligands for human sex hormone binding globulin
Journal of Medicinal Chemistry
Cherkasov, A. and Shi, Z. and Fallahi, M. and Hammond, G.L.
DOI: 10.1021/jm049087f
2005'Inductive' charges on atoms in proteins: Comparative docking with the extended steroid benchmark set and discovery of a novel SHBG ligand
Journal of Chemical Information and Modeling
DOI: 10.1021/ci0498158
2005Sea bass (Dicentrarchus labrax) sex hormone binding globulin: Molecular and biochemical properties and phylogenetic comparison of its orthologues in multiple fish species
Molecular and Cellular Endocrinology
Miguel-Queralt, S. and Avvakumov, G.V. and Blázquez, M. and Piferrer, F. and Hammond, G.L.
DOI: 10.1016/j.mce.2004.10.004
2005Repression of the human sex hormone-binding globulin gene in sertoli cells by upstream stimulatory transcription factors
Journal of Biological Chemistry
Selva, D.M. and Hogeveen, K.N. and Hammond, G.L.
DOI: 10.1074/jbc.M409616200
2005Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study
Breast Cancer Research
DOI: 10.1186/bcr798
2004The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility
Journal of Lipid Research
Selva, D.M. and Hirsch-Reinshagen, V. and Burgess, B. and Zhou, S. and Chan, J. and McIsaac, S. and Hayden, M.R. and Hammond, G.L. and Vogl, A.W. and Wellington, C.L.
DOI: 10.1194/jlr.M400007-JLR200
2004Molecular and functional characterization of sex hormone binding globulin in zebrafish
Endocrinology
Miguel-Queralt, S. and Knowlton, M. and Avvakumov, G.V. and Al-Nouno, R. and Kelly, G.M. and Hammond, G.L.
DOI: 10.1210/en.2004-0678
2004Association between the T27C polymorphism in the cytochrome P450 c17a (CYP17) gene and risk factors for breast cancer
Breast Cancer Research and Treatment
Hong, C.-C. and Thompson, H.J. and Jiang, C. and Hammond, G.L. and Tritchler, D. and Yaffe, M. and Boyd, N.F.
DOI: 10.1007/s10549-004-0780-7
2004Serum distribution of the major metabolites of norgestimate in relation to its pharmacological properties
Contraception
Hammond, G.L. and Abrams, L.S. and Creasy, G.W. and Natarajan, J. and Allen, J.G. and Siiteri, P.K.
DOI: 10.1016/S0010-7824(02)00473-0
2003Sex Hormone-Binding Globulin (SHBG)
Encyclopedia of Hormones
DOI: 10.1016/b0-12-341103-3/00269-2
2003Val158Met polymorphism in catechol-O-methyltransferase gene associated with risk factors for breast cancer
Cancer Epidemiology Biomarkers and Prevention
Hong, C.-C. and Thompson, H.J. and Jiang, C. and Hammond, G.L. and Tritchler, D. and Yaffe, M. and Boyd, N.F.
2003Structure/function analyses of human sex hormone-binding globulin: Effects of zinc on steroid-binding specificity
Journal of Steroid Biochemistry and Molecular Biology
DOI: 10.1016/S0960-0760(03)00195-X
2003Lack of effect of a low-fat high-carbohydrate diet on ovarian hormones in premenopausal women: results from a randomized trial.
IARC scientific publications
Boyd, N.F. and Greenberg, C. and Martin, L. and Stone, J. and Hammond, G. and Minkin, S. and Canadian Diet and Breast Cancer Prevention Study Group
2002The association of breast mitogens with mammographic densities
British Journal of Cancer
Boyd, N.F. and Stone, J. and Martin, L.J. and Jong, R. and Fishell, E. and Yaffe, M. and Hammond, G. and Minkin, S.
DOI: 10.1038/sj.bjc.6600537
2002Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation
Journal of Biological Chemistry
Grishkovskaya, I. and Avvakumov, G.V. and Hammond, G.L. and Catalano, M.G. and Muller, Y.A.
DOI: 10.1074/jbc.M203999200
2002Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction
Journal of Clinical Investigation
Hogeveen, K.N. and Cousin, P. and Pugeat, M. and Dewailly, D. and Soudan, B. and Hammond, G.L.
DOI: 10.1172/JCI0214060
2002Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site
Journal of Molecular Biology
Grishkovskaya, I. and Avvakumov, G.V. and Hammond, G.L. and Muller, Y.A.
DOI: 10.1016/S0022-2836(02)00169-9
2002Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol
Journal of Biological Chemistry
Avvakumov, G.V. and Grishkovskaya, I. and Muller, Y.A. and Hammond, G.L.
DOI: 10.1074/jbc.M207762200
2002Access of reproductive steroids to target tissues
Obstetrics and Gynecology Clinics of North America
Hammond, G.L.
DOI: 10.1016/S0889-8545(02)00008-6
2002O-Glycosylation of human sex hormone-binding globulin is essential for inhibition of estradiol-induced MCF-7 breast cancer cell proliferation
Molecular and Cellular Endocrinology
Raineri, M. and Catalano, M.G and Hammond, G.L and Avvakumov, G.V and Frairia, R. and Fortunati, N.
DOI: 10.1016/S0303-7207(01)00725-0
2002A human sex hormone-binding globulin isoform accumulates in the acrosome during spermatogenesis
Journal of Biological Chemistry
Selva, D.M. and Hogeveen, K.N. and Seguchi, K. and Tekpetey, F. and Hammond, G.L.
DOI: 10.1074/jbc.M205903200
200218F-labeled difluoroestradiols: Preparation and preclinical evaluation as estrogen receptor-binding radiopharmaceuticals
Steroids
Seimbille, Y. and Rousseau, J. and Bénard, F. and Morin, C. and Ali, H. and Avvakumov, G. and Hammond, G.L. and van Lier, J.E.
DOI: 10.1016/S0039-128X(02)00025-9
2002Resolution of the Human Sex Hormone-binding Globulin Dimer Interface and Evidence for Two Steroid-binding Sites per Homodimer
Journal of Biological Chemistry
Avvakumov, G.V. and Grishkovskaya, I. and Muller, Y.A. and Hammond, G.L.
DOI: 10.1074/jbc.M106274200
2001Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy
American Journal of Obstetrics and Gynecology
Hammond, G.L. and Rabe, T. and Wagner, J.D.
DOI: 10.1067/mob.2001.117415
2001Human Sex Hormone-binding Globulin Promoter Activity Is Influenced by a (TAAAA)
n Repeat Element within an Alu Sequence
Journal of Biological Chemistry
Hogeveen, K.N. and Talikka, M. and Hammond, G.L.
DOI: 10.1074/jbc.M104681200
2001Interactions between human plasma sex hormone-binding globulin and xenobiotic ligands
Journal of Steroid Biochemistry and Molecular Biology
Jury, H.H. and Zacharewski, T.R. and Hammond, G.L.
DOI: 10.1016/S0960-0760(00)00168-0
2000The rabbit sex hormone-binding globulin gene: Structural organization and characterization of its 5'-flanking region
Endocrinology
Ip, Y.-C. and Lee, W.M. and Hammond, G.L.
DOI: 10.1210/endo.141.4.7406
2000Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity
Journal of Clinical Endocrinology and Metabolism
Emptoz-Bonneton, A. and Cousin, P. and Seguchi, K. and Avvakumov, G.V. and Bully, C. and Hammond, G.L. and Pugeat, M.
DOI: 10.1210/jc.85.1.361
2000Crystal structure of human sex hormone-binding globulin: Steroid transport by a laminin G-like domain
EMBO Journal
Grishkovskaya, I. and Avvakumov, G.V. and Sklenar, G. and Dales, D. and Hammond, G.L. and Muller, Y.A.
DOI: 10.1093/emboj/19.4.504
2000Estrogen receptor- and aryl hydrocarbon receptor-mediated activities of a coal-tar creosote
Environmental Toxicology and Chemistry
Fielden, M.R. and Wu, Z.-F. and Sinal, C.J. and Jury, H.H. and Bend, J.R. and Hammond, G.L. and Zacharewski, T.R.
DOI: 10.1002/etc.5620190507
2000Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site
Journal of Biological Chemistry
Avvakumov, G.V. and Muller, Y.A. and Hammond, G.L.
DOI: 10.1074/jbc.M004484200
2000Crystallization of the N-terminal domain of human sex hormone-binding globulin, the major sex steroid carrier in blood
Acta Crystallographica Section D: Biological Crystallography
Grishkovskaya, I. and Sklenar, G. and Avvakumov, G.V. and Dales, D. and Behlke, J. and Hammond, G.L. and Muller, Y.A.
DOI: 10.1107/S0907444999012883
1999The SHBG gene and hormone dependence of breast cancer: A novel mechanism of hormone dependence of MCF-7 human breast cancer cells based upon SHBG
Breast Cancer
Murayama, Y. and Hammond, G.L. and Sugihara, K.
DOI: 10.1007/BF02966450
1999Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock
Genomics
Libert, Q. and Wielockx, B. and Hammond, G.L. and Brouckaert, P. and Rers, W. and Bliott, R.W.
DOI: 10.1006/geno.1998.5677
1999Influence of glycosylation on the clearance of recombinant human sex hormone-binding globulin from rabbit blood
Journal of Steroid Biochemistry and Molecular Biology
Cousin, P. and Déchaud, H. and Grenot, C. and Lejeune, H. and Hammond, G.L. and Pugeat, M.
DOI: 10.1016/S0960-0760(99)00101-6
1999Role of sex hormone-binding globulin in target uptake of radiolabelled steroids: Investigations in transgenic models
Journal of Labelled Compounds and Radiopharmaceuticals
1999Expression and regulation of human sex hormone-binding globulin transgenes in mice during development
Endocrinology
Jänne, M. and Hogeveen, K.N. and Deol, H.K. and Hammond, G.L.
DOI: 10.1210/endo.140.9.7004
1999N-glycans are not the signal for apical sorting of corticosteroid binding globulin in MDCK cells
FEBS Letters
Larsen, J.E. and Avvakumov, G.V. and Hammond, G.L. and Vogel, L.K.
DOI: 10.1016/S0014-5793(99)00526-8
1999Establishment of a mouse Sertoli cell line producing rat androgen- binding protein (ABP)
Steroids
DOI: 10.1016/S0039-128X(98)00030-0
1998Hepatocyte nuclear factor-4 controls transcription from a TATA-less human sex hormone-binding globulin gene promoter
Journal of Biological Chemistry
Jänne, M. and Hammond, G.L.
DOI: 10.1074/jbc.273.51.34105
1998Human sex hormone-binding globulin gene expression in transgenic mice
Molecular Endocrinology
Jänne, M. and Deol, H.K. and Power, S.G.A. and Yee, S.-P. and Hammond, G.L.
DOI: 10.1210/mend.12.1.0050
1998Divergent changes in plasma ACTH and pituitary POMC mRNA after cortisol administration to late-gestation ovine fetus
American Journal of Physiology - Endocrinology and Metabolism
Jeffray, T.M. and Matthews, S.G. and Hammond, G.L. and Challis, J.R.G.
DOI: 10.1152/ajpendo.1998.274.3.e417
1998Control of the membrane sex hormone-binding globulin-receptor (SHBG-R) in MCF-7 cells: Effect of locally produced SHBG
Steroids
DOI: 10.1016/S0039-128X(98)00021-X
1998Effects of a low-fat high-carbohydrate diet on plasma sex hormones in premenopausal women: results from a randomized controlled trial
British Journal of Cancer
NF Boyd and for the Canadian Diet and Breast Cancer Prevention Study Group (See Appendix I) and GA Lockwood and CV Greenberg and LJ Martin and DL Tritchler
DOI: 10.1038/bjc.1997.348
07/1997The effects of estradiol-17ß infusion into fetal sheep in late gestation
Endocrine
Wang, S. and Matthews, S.G. and Jeffray, T.M. and Stevens, M.Y. and Yang, K. and Hammond, G.L. and Challis, J.R.G.
DOI: 10.1007/BF02820503
1997Rabbit sex hormone binding globulin: Primary structure, tissue expression, and structure/function analyses by expression in Escherichia coli
Journal of Endocrinology
Lee, W.M. and Wong, A.S.T. and Tu, A.W.K. and Cheung, C.-H. and Li, J.C.H. and Hammond, G.L.
DOI: 10.1677/joe.0.1530373
1997ABP sertolienne et synthese de l'adn dans les cellules germinales du rat et de la souris prepuberes
Andrologie
Gerard, A. and Clerc, A. and Adam, M. and Franck, P. and Nabet, F. and Closset, J. and Hammond, G. and Gerard, H.
1997Glucocorticoids induce corticosteroid-binding globulin biosynthesis by immature mouse liver and kidney
Journal of Steroid Biochemistry and Molecular Biology
Zhao, X.-F. and Scrocchi, L.A. and Hammond, G.L.
DOI: 10.1016/S0960-0760(96)00181-1
1997Determinants of steroid hormone bioavailability
Biochemical Society Transactions
DOI: 10.1042/bst0250577
1997Hepatic nuclear proteins that bind cis-regulatory elements in the proximal promoter of the rat corticosteroid-binding globulin gene
Molecular and Cellular Endocrinology
Zhao, X.-F. and Underhill, D.A. and Hammond, G.L.
DOI: 10.1016/S0303-7207(96)03992-5
1997Differential Effects of Betamethasone and Dexamethasone Fetal Administration of Parturition in Sheep
Journal of the Society for Gynecologic Investigation
Jan B. Derks and Dino A. Giussani and Lecia M. Van Dam and Susan L. Jenkins and James A. Winter and Xian F. Zhao and Geoffrey L. Hammond and Peter W. Nathanielsz
DOI: 10.1177/107155769600300607
11/1996Murine corticosteroid binding globulin localizes to early embryo trophoblasts
Placenta
M.G. Baines and E. Antecka and G.L. Hammond
DOI: 10.1016/s0143-4004(96)90241-6
07/1996Growth response of adult germ cells to rat androgen-binding protein and human sex hormone-binding globulin
Hormone Research in Paediatrics
Gérard, A. and Bedjou, R. and Clerc, A. and Maachi, F. and Closset, J. and Hammond, G.L. and Nabet, F. and Gèrard, H.
DOI: 10.1159/000184791
1996Sex hormone-binding globulin: Gene organization and structure/function analyses
Hormone Research in Paediatrics
Hammond, G.L. and Bocchinfuso, W.P.
DOI: 10.1159/000184787
1996Developmental regulation of corticosteroid-binding globulin biosynthesis in the baboon fetus
Endocrinology
Pepe, G.J. and Jury, H.H. and Hammond, G.L. and Albrecht, E.D.
DOI: 10.1210/endo.137.8.8754758
1996Sex hormone-binding globulin/androgen-binding protein: Steroid-binding and dimerization domains
Journal of Steroid Biochemistry and Molecular Biology
Hammond, G.L. and Bocchinfuso, W.P.
DOI: 10.1016/0960-0760(95)00110-L
1995cis-Regulatory elements within the proximal promoter of the rat gene encoding corticosteroid-binding globulin
Gene
Underhill, D.A. and Hammond, G.L.
DOI: 10.1016/0378-1119(95)00337-6
1995Potential functions of plasma steroid-binding proteins
Trends in Endocrinology and Metabolism
Hammond, G.L.
DOI: 10.1016/1043-2760(95)00162-X
1995Corticosteroid-binding globulin (CBG) in fetal development
Journal of Steroid Biochemistry and Molecular Biology
Challis, J.R.G. and Berdusco, E.T.M. and Jeffray, T.M. and Yang, K. and Hammond, G.L.
DOI: 10.1016/0960-0760(95)00100-E
1995Resolution of the Steroid-Binding and Dimerization Domains of Human Sex Hormone-Binding Globulin by Expression in Escherichia Coli
Biochemistry
Hildebrand, C. and Bocchinfuso, W.P. and Dales, D. and Hammond, G.L.
DOI: 10.1021/bi00010a012
1995Corticosteroid-binding globulin (CBG) production by hepatic and extra-hepatic sites in the ovine fetus; effects of CBG on glucocorticoid negative feedback on pituitary cells in vitro
Journal of Endocrinology
Berdusco, E.T.M. and Yang, K. and Hammond, G.L. and Challis, J.R.G.
DOI: 10.1677/joe.0.1460121
1995Squirrel monkey corticosteroid-binding globulin: primary structure and comparison with the human protein
Endocrinology
G. L. Hammond
DOI: 10.1210/en.134.2.891
02/1994Glycosylation of Human Corticosteroid-Binding Globulin. Differential Processing and Significance of Carbohydrate Chains at Individual Sites
Biochemistry
Avvakumov, G.V. and Hammond, G.L.
DOI: 10.1021/bi00185a012
1994Substitutions of tryptophan residues in human corticosteroid-binding globulin: Impact on steroid binding and glycosylation
Journal of Steroid Biochemistry and Molecular Biology
Avvakumov, G.V. and Hammond, G.L.
DOI: 10.1016/0960-0760(94)90010-8
1994Serum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene
Contraception
Hammond, G.L. and Bocchinfuso, W.P. and Orava, M. and Smith, C.L. and Van Den Ende, A. and Van Enk, A.
DOI: 10.1016/0010-7824(94)90018-3
1994Structure and chromosomal location of the gene encoding mouse corticosteroid-binding globulin: strain differences in coding sequence and steroid-binding activity
Gene
Orava, M. and Zhao, X.F. and Leiter, E. and Hammond, G.L.
DOI: 10.1016/0378-1119(94)90387-5
1994Steroid-Binding and Dimerization Domains of Human Sex Hormone-Binding Globulin Partially Overlap: Steroids and Ca2+ Stabilize Dimer Formation
Biochemistry
Bocchinfuso, W.P. and Hammond, G.L.
DOI: 10.1021/bi00201a008
1994Interleukin-6 inhibits corticosteroid-binding globulin synthesis by human hepatoblastoma-derived (Hep G2) cells.
Endocrinology
L Bartalena and G L Hammond and A Farsetti and I L Flink and J Robbins
DOI: 10.1210/endo.133.1.8391424
07/1993Decreased cortisol-binding affinity of transcortin Leuven is associated with an amino acid substitution at residue-93
Steroids
Hugo Van Baelen and Stephen G.A. Power and Geoffrey L. Hammond
DOI: 10.1016/0039-128x(93)90072-u
06/1993Spatial and temporal distribution of corticosteroid-binding globulin and its messenger ribonucleic acid in embryonic and fetal mice.
Endocrinology
L A Scrocchi and M Orava and C L Smith and V K Han and G L Hammond
DOI: 10.1210/endo.132.2.7916682
02/1993Spatial and temporal distribution of corticosteroid-binding globulin and its messenger ribonucleic acid in embryonic and fetal mice
Endocrinology
1993Interleukin-6 inhibits corticosteroid-binding globulin synthesis by human hepatoblastoma-derived (Hep G2) cells
Endocrinology
1993Tissue distribution of a
1 -proteinase inhibitor messenger ribonucleic acid and its regulation by glucocorticoids in fetal and neonatal sheep
Biology of Reproduction
Berdusco, E.T.M. and Yang, K. and Challis, J.R.G. and Hammond, G.L.
DOI: 10.1095/biolreprod49.4.816
1993Glucocorticoid-induced increase in plasma corticosteroid-binding globulin levels in fetal sheep is associated with increased biosynthesis and alterations in glycosylation
Endocrinology
Berdusco, E.T.M. and Hammond, G.L. and Jacobs, R.A. and Grolla, A. and Akagi, K. and Langlois, D. and Challis, J.R.G.
DOI: 10.1210/endo.132.5.8477651
1993Effect of burn injury on corticosteroid-binding globulin levels in plasma and wound fluid
Wound Repair and Regeneration
Garrel, D.R. and Zhang, L. and Zhao, X.?F. and Hammond, G.L.
DOI: 10.1046/j.1524-475X.1993.10105.x
1993Corticosteroid-binding globulin biosynthesis in the mouse liver and kidney during postnatal development
Endocrinology
Scrocchi, L.A. and Hearn, S.A. and Han, V.K.M. and Hammond, G.L.
DOI: 10.1210/endo.132.2.8425503
1993Physical mapping of four serpin genes: a1-antitrypsin, a1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome 14q32.1
American Journal of Human Genetics
1993Glycosylation of human corticosteroid-binding globulin at aspargine 238 is necessary for steroid binding
Journal of Biological Chemistry
Avvakumov, G.V. and Warmels-Rodenhiser, S. and Hammond, G.L.
1993Cloning of an ovine 11ß-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: Tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development
Endocrinology
Yang, K. and Smith, C.L. and Dales, D. and Hammond, G.L. and Challis, J.R.G.
DOI: 10.1210/endo.131.5.1425412
1992Molecular analyses of a human sex hormone-binding globulin variant: Evidence for an additional carbohydrate chain
Journal of Clinical Endocrinology and Metabolism
Power, S.G.A. and Bocchinfuso, W.P. and Pallesen, M. and Warmels-Rodenhiser, S. and Baelen, H.V. and Hammond, G.L.
DOI: 10.1210/jcem.75.4.1400872
1992Structure/function analyses of human sex hormone-binding globulin by site-directed mutagenesis
FEBS Letters
Bocchinfuso, W.P. and Warmels-Rodenhiser, S. and Hammond, G.L.
DOI: 10.1016/0014-5793(92)81253-I
1992Hormonal regulation of corticosteroid-binding globulin biosynthesis in the male rat
Endocrinology
Smith, C.L. and Hammond, G.L.
DOI: 10.1210/endo.130.4.1547738
1992Characterization of an ovine glucocorticoid receptor cDNA and developmental changes in its mRNA levels in the fetal sheep hypothalamus, pituitary gland and adrenal
Journal of Molecular Endocrinology
Yang, K. and Hammond, G.L. and Challis, J.R.G.
DOI: 10.1677/jme.0.0080173
1992Novel Testicular Products of the Human SHBG/ABP Gene
Follicle Stimulating Hormone
DOI: 10.1007/978-1-4684-7103-8_21
1992A Leu ¿ His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol
Journal of Steroid Biochemistry and Molecular Biology
Smith, C.L. and Power, S.G.A. and Hammond, G.L.
DOI: 10.1016/0960-0760(92)90107-T
1992Selective removal of glycosylation sites from sex hormone-binding globulin by site-directed mutagenesis
Endocrinology
Bocchinfuso1, W.P. and Ma, K.-L. and Lee, W.M. and Rodenhiser, S.W. and Hammond, G.L.
DOI: 10.1210/endo.131.5.1425432
1992Levels of surfactant-associated protein messenger ribonucleic acids in rabbit lung during perinatal development and after hormonal treatment
Endocrinology
Connelly, I.H. and Hammond, G.L. and Harding, P.G.R. and Possmayer, F.
DOI: 10.1210/endo-129-5-2583
1991Effect of adrenocorticotropin administration on the biosynthesis of corticosteroid-binding globulin in fetal sheep
Endocrinology
Jacobs, R.A. and Han, V.K.M. and Hammond, G.L. and Challis, J.R.G.
DOI: 10.1210/endo-128-4-1960
1991Ontogeny of corticosteroid-binding globulin biosynthesis in the rat
Endocrinology
Smith, C.L. and Hammond, G.L.
DOI: 10.1210/endo-128-2-983
1991An amino acid substitution in biobreeding rat corticosteroid binding globulin results in reduced steroid binding affinity
Journal of Biological Chemistry
1991Pro-opiomelanocortin messenger RNA levels increase in the fetal sheep pituitary during late gestation
Journal of Endocrinology
Yang, K. and Challis, J.R.G. and Han, V.K.M. and Hammond, G.L.
DOI: 10.1677/joe.0.1310483
1991Expression and differential glycosylation of human sex hormone-binding globulin by mammalian cell lines
Molecular Endocrinology
Bocchinfuso, W.P. and Warmels-Rodenhiser, S. and Hammond, G.L.
DOI: 10.1210/mend-5-11-1723
1991Molecular studies of corticosteroid binding globulin structure, biosynthesis and function
Journal of Steroid Biochemistry and Molecular Biology
Hammond, G.L. and Smith, C.L. and Underhill, D.A.
DOI: 10.1016/0960-0760(91)90300-T
1991Interaction between corticosteroid binding globulin and activated leukocytes in vitro
Biochemical and Biophysical Research Communications
Hammond, G.L. and Smith, C.L. and Underhill, C.M. and Nguyen, V.T.T.
DOI: 10.1016/S0006-291X(05)80189-5
1990The human corticosteroid binding globulin gene is located on chromosome 14q31–q32.1 near two other serine protease inhibitor genes
Human Genetics
Seralini, G.-E. and Bérubé, D. and Gagné, R. and Hammond, G.L.
DOI: 10.1007/BF00205177
1990Studies on steroid binding proteins in normal tissues and tumor cell lines
Revista Espanola de Fisiologia
Reventos, J. and Hammond, G.L. and Musto, N.A. and Bardin, C.W.
1990Localization of the human sex hormone-binding globulin gene (SHBG) to the short arm of chromosome 17 (17p12¿p13)
Cytogenetic and Genome Research
Bérubé, D. and Séralini, G.E. and Gagné, R. and Hammond, G.L.
DOI: 10.1159/000132958
1990Rabbit corticosteroid-binding globulin: Primary structure and biosynthesis during pregnancy
Molecular Endocrinology
Seralini, G.-E. and Smith, C.L. and Hammond, G.L.
DOI: 10.1210/mend-4-8-1166
1990Expression of mature pulmonary surfactant-associated protein B (SP-B) in Escherichia coli using truncated human SP-B cDNAs
Biochemistry and Cell Biology
Yao, L.-J. and Richardson, C. and Ford, C. and Mathialagan, N. and Mackie, G. and Hammond, G.L. and Harding, P.G.R. and Possmayer, F.
DOI: 10.1139/o90-080
1990Molecular properties of corticosteroid binding globulin and the sex-steroid binding proteins
Endocrine Reviews
Hammond, G.L.
DOI: 10.1210/edrv-11-1-65
1990A role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils
Journal of Clinical Endocrinology and Metabolism
Hammond, G.L. and Smith, C.L. and Paterson, N.A.M. and Sibbald, W.J.
DOI: 10.1210/jcem-71-1-34
1990The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs
Molecular Endocrinology
Hammond, G.L. and Underhill, D.A. and Rykse, H.M. and Smith, C.L.
DOI: 10.1210/mend-3-11-1869
1989Organization of the human corticosteroid binding globulin geneand analysis of its 5’-flankingregion
Molecular Endocrinology
Underhill, D.A. and Hammond, G.L.
DOI: 10.1210/mend-3-9-1448
1989Identification of proteins immunochemically related to human pregnancy-specific ß
1 -glycoprotein in the rat placenta
Endocrinology
Ogilvie, S. and Kvello-Stenstrom, A.G. and Hammond, G. and Shiverick, K.T. and Buhi, W.C. and Larkin, L.H.
DOI: 10.1210/endo-125-1-287
1989Isolation and characterization of the cDNA for pulmonary surfactant-associated protein-B (SP-B) in the rabbit
Biochemical and Biophysical Research Communications
Xu, J. and Richardson, C. and Ford, C. and Spencer, T. and Li-juan, Y. and Mackie, G. and Hammond, G. and Possmayer, F.
DOI: 10.1016/0006-291X(89)91659-8
1989Rat corticosteroid binding globulin: Primary structure and messenger ribonucleic acid levels in the liver under different physiological conditions
Molecular Endocrinology
Smith, C.L. and Hammond, G.L.
DOI: 10.1210/mend-3-2-420
1989Biological half-life and transfer of maternal corticosteroid-binding globulin to amniotic fluid in the rabbit
Endocrinology
Seralini, G.-E. and Underhill, C.M. and Smith, C.L. and Nguyen, V.T.T. and Hammond, G.L.
DOI: 10.1210/endo-125-3-1321
1989Hormonal regulation of rat Androgen-Binding Protein (ABP) messenger ribonucleic acid and homology of human testosterone-estradiol-binding globulin and abp complementary deoxyribonucleic acids
Molecular Endocrinology
Reventos, J. and Hammond, G.L. and Crozat, A. and Brooks, D.E. and Gunsalus, G.L. and Bardin, C.W. and Musto, N.A.
DOI: 10.1210/mend-2-2-125
1988Time-resolved immunofluorometric assay of sex-hormone binding globulin
Clinical Chemistry
Niemi, S. and Maentausta, O. and Bolton, N.J. and Hammond, G.L.
1988Molecular Analyses of Human Corticosteroid-Binding Globulin: Expression and Gene Structurea
Annals of the New York Academy of Sciences
HAMMOND, G.L.
DOI: 10.1111/j.1749-6632.1988.tb48845.x
1988The amino acid sequence of rat CBG deduced from a cDNA, and identification of CBG mRNA in the liver under different physiological states
Steroids
Smith, C.L. and Hammond, G.L.
DOI: 10.1016/0039-128X(88)90132-8
1988Isolation and characterization of the structural region of the human CBG gene
Steroids
Underhill, D.A. and Hammond, G.L.
DOI: 10.1016/0039-128X(88)90131-6
1988Corticosteroid binding globulin, testosterone-estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid receptors
Journal of Steroid Biochemistry
Bardin, C.W. and Gunsalus, G.L. and Musto, N.A. and Cheng, C.Y. and Reventos, J. and Smith, C. and Underhill, D.A. and Hammond, G.
DOI: 10.1016/0022-4731(88)90085-4
1988Time-resolved immunofluorometric assay of human SHBG
Steroids
Niemi, S. and Mäentausta, O. and Bolton, N.J. and Hammond, G.L.
DOI: 10.1016/0039-128X(88)90173-0
1988Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors
Proceedings of the National Academy of Sciences of the United States of America
Hammond, G.L. and Smith, C.L. and Goping, I.S. and Underhill, D.A. and Harley, M.J. and Reventos, J. and Musto, N.A. and Gunsalus, G.L. and Bardin, C.W.
DOI: 10.1073/pnas.84.15.5153
1987The cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain
FEBS Letters
Hammond, G.L. and Underhill, D.A. and Smith, C.L. and Goping, I.S. and Harley, M.J. and Musto, N.A. and Cheng, C.Y. and Bardin, C.W.
DOI: 10.1016/0014-5793(87)80121-7
1987Plasma levels of cortisol and corticosteroid binding globulin during use of norplantr -2 implants
Contraception
Olsson, S.-E. and Odlind, V. and Hammond, G.
DOI: 10.1016/0010-7824(87)90072-2
1987Isolation and Characterization of cDNA Probes for Human CBG and Rat ABP
Gene Regulation by Steroid Hormones III
G. L. Hammond and J. Reventos and N. A. Musto and G. L. Gunsalus and C. W. Bardin
DOI: 10.1007/978-1-4612-4686-2_10
1987Identification and measurement of sex hormone binding globulin1 (SHBG) and corticosteroid binding globulin2 (CBG) in human saliva
European Journal of Endocrinology
G. L. Hammond and M. S. Langley
DOI: 10.1530/acta.0.1120603
08/1986Physicochemical characteristics of human sex hormone binding globulin: Evidence for two identical subunits
Journal of Steroid Biochemistry
Hammond, G.L. and Robinson, P.A. and Sugino, H. and Ward, D.N. and Finne, J.
DOI: 10.1016/0022-4731(86)90442-5
1986Identification and measurment of sex hormone binding globulin (SHBG) and corticosteroid binding globulin (CBG) in human saliva
Acta Endocrinologica
Hammond, G.L. and Langley, M.S.
1986Sex hormone-binding globulin - still many questions
Scandinavian Journal of Clinical and Laboratory Investigation
Lindstedt, G. and Lundberg, P.-A. and Hammond, G.L. and Vihko, R.
DOI: 10.3109/00365518509160964
1985Serum steroid binding proteins and the bioavailability of estradiol in relation to breast diseases1, 2
Journal of the National Cancer Institute
Langley, M.S. and Hammond, G.L. and Anderson, D.C. and Alan, B. and Sellwood, R.A.
DOI: 10.1093/jnci/75.5.823
1985Identification and characterization of a human corticosteroid binding globulin variant with a reduced affinity for cortisol
Journal of Endocrinology
Robinson, P.A. and Hammond, G.L.
DOI: 10.1677/joe.0.1040269
1985A phylogenetic study of the structural and functional characteristics of corticosteroid binding globulin in primates
Journal of Endocrinology
Robinson, P.A. and Hawkey, C. and Hammond, G.L.
DOI: 10.1677/joe.0.1040251
1985A solid-phase radioimmunoassay for human corticosteroid binding globulin
Journal of Endocrinology
Robinson, P.A. and Langley, M.S. and Hammond, G.L.
DOI: 10.1677/joe.0.1040259
1985A liquid-phase immunoradiometric assay (IRMA) for human sex hormone binding globulin (SHBG)
Journal of Steroid Biochemistry
Hammond, G.L. and Langley, M.S. and Robinson, P.A.
DOI: 10.1016/0022-4731(85)90192-X
1985Serum steroid binding protein concentrations, distribution of progestogens, and bioavailability of testosterone during treatment with contraceptives containing desogestrel or levonorgestrel
Fertility and Sterility
DOI: 10.1016/s0015-0282(16)47956-2
07/1984Characterization of a monoclonal antibody to human sex hormone binding globulin
FEBS Letters
Hammond, G.L. and Robinson, P.A.
DOI: 10.1016/0014-5793(84)80268-9
1984Serum sex hormone-binding globulin during puberty in girls and in different types of adolescent menstrual cycles
Acta Endocrinologica
Apter, D. and Bolton, N.J. and Hammond, G.L. and Vihko, R.
1984A versatile method for the determination of serum cortisol binding globulin and sex hormone binding globulin binding capacities
Clinica Chimica Acta
Geoffrey L. Hammond and Pertti L.A. Lähteenmäki
DOI: 10.1016/0009-8981(83)90237-1
07/1983Measurement of sex hormone binding globulin in human amniotic fluid: its relationship to protein and testosterone concentrations, and fetal sex
Clinical Endocrinology
DOI: 10.1111/j.1365-2265.1983.tb00582.x
04/1983Progesterone, androstenedione, testosterone, 5a-dihydrotestosterone and androsterone concentrations in specific regions of the human brain
Journal of Steroid Biochemistry
G.L. Hammond and J. Hirvonen and R. Vihko
DOI: 10.1016/0022-4731(83)90086-9
02/1983Serum non-protein bound percentage and distribution of the progestin ST-1435: No effect of ST-1435 treatment on plasma SHBG and CBG binding capacities
Acta Endocrinologica
Lahteenmaki, P.L.A. and Hammond, G.L. and Luukkainen, T.
DOI: 10.1530/acta.0.1020307
1983Distribution and percentages of non-protein bound contraceptive steroids in human serum
Journal of Steroid Biochemistry
Geoffrey L. Hammond and Pertti L.A. Lähteenmäki and Pekka Lähteenmäki and Tapani Luukkainen
DOI: 10.1016/0022-4731(82)90629-x
10/1982Serum concentrations of total and non-protein-bound oestradiol in patients with breast cancer and in normal controls
International Journal of Cancer
J. W. Moore and G. M. G. Clark and R. D. Bulbrook and J. L. Hayward and J. T. Murai and G. L. Hammond and P. K. Siiteri
DOI: 10.1002/ijc.2910290105
01/1982The Serum Transport of Steroid Hormones
Proceedings of the 1981 Laurentian Hormone Conference
DOI: 10.1016/b978-0-12-571138-8.50016-0
1982Versatile semi-automated sample processor and gamma counter to increase radioimmunoassay efficiency
Clinical Chemistry
Vihko, R. and Bolton, N. and Hammond, G.L.
DOI: 10.1093/clinchem/28.4.699
1982Free estradiol in postmenopausal women with and without endometrial cancer,Freies östradiol bei frauen nach der menopause mit bzw. ohne endometriumkarzinom
Gynakologisch-geburtshilfliche Rundschau
Davidson, B.J. and Gambone, J.C. and Lagasse, L.D. and Castaldo, T.W. and Hammond, G.L. and Siiteri, P.K. and Judd, H.L.
DOI: 10.1159/000269292
1982Distribution and concentrations of androgens in epithelial and stromal compartments of the human benign hypertrophic prostate
Journal of Endocrinology
DOI: 10.1677/joe.0.0900125
07/1981Free Estradiol in Postmenopausal Women with and without Endometrial Cancer
The Journal of Clinical Endocrinology & Metabolism
DOI: 10.1210/jcem-52-3-404
03/1981Long-Term Effects of Endocrine Treatment on Serum Pituitary Hormones in Advanced Prostatic Carcinoma Patients
Scandinavian Journal of Urology and Nephrology
O. Lukkarinen and G. L. Hammond and M. Kontturi and R. Vihko
DOI: 10.3109/00365598109179604
01/1981Gynecomastia and high serum testosterone in a 10 year old boy,Gynekomastia ja korkea seerumin testosteroniarvo murrosikäiseliä pojalla.
Duodecim
Viinikka, L. and Hammond, G.L. and Hortling, H. and Leinonen, P. and Vihko, R.
1981The clinical and endocrine evaluation of a pubertal boy with incomplete male pseudohermaphroditism type 1
Annals of Clinical Research
Viinikka, L. and Hammond, G.L. and Hortling, H. and Leinonen, P. and Vihko, R.
1981Serum non-protein bound percentages and distribution of contraceptive steroids
Journal of Steroid Biochemistry
Hammond, G.L. and Lahteenmaki, P. and Lahteenmaki, P. and Luukkainen, T.
1981Serum sex hormone-binding globulin capacity and the percentage of free estradiol in postmenopausal women with and without endometrial carcinoma
American Journal of Obstetrics and Gynecology
J.A. Nisker and G.L. Hammond and B.J. Davidson and A.M. Frumar and N.K. Takaki and H.L. Judd and P.K. Siiteri
DOI: 10.1016/0002-9378(80)90080-0
11/1980Peripheral and prostatic vein steroid concentrations in benign prostatic hypertrophy patients before and after removal of the adenoma
Scandinavian Journal of Urology and Nephrology
Lukkarinen, O. and Hammond, G.L. and Kontturi, M. and Vihko, R.
DOI: 10.3109/00365598009179566
1980More on Fatness and Reproduction
New England Journal of Medicine
Nisker, J.A. and Hammond, G.L. and Siiteri, P.K. and Frisch, R.E. and Fishman, J.
DOI: 10.1056/NEJM198011063031919
1980Testosterone and some of its precursors and metabolites in the human epididymis
Journal of Clinical Endocrinology and Metabolism
Leinonen, P. and Hammond, G.L. and Vihko, R.
DOI: 10.1210/jcem-51-3-423
1980Long-term effects of endocrine treatment on serum steroids in advanced prostatic carcinoma patients
Investigative Urology
Lukkarinen, O. and Hammond, G.L. and Kontturi, M. and Vihko, R.
1980Effect of oestrogen treatment on testicular LH/HCG receptors and endogenous steroids in prostatic cancer patients
Clinical Endocrinology
DOI: 10.1111/j.1365-2265.1980.tb03424.x
1980Estimation of the percentage of free steroid in undiluted serum by centrifugal ultrafiltration-dialysis
Journal of Biological Chemistry
Hammond, G.L. and Nisker, J.A. and Jones, L.A. and Siiteri, P.K.
1980SERUM PREGNENOLONE, PROGESTERONE, 17a-HYDROXYPROGESTERONE, ANDROSTENEDIONE, TESTOSTERONE, 5a-DIHYDROTESTOSTERONE AND ANDROSTERONE DURING PUBERTY IN BOYS
Clinical Endocrinology
A. PAKARINEN and G. L. HAMMOND and R. VIHKO
DOI: 10.1111/j.1365-2265.1979.tb03098.x
11/1979Adrenocortical function in puberty serum ACTH, cortisol and dehydroepiandrosterone in girls and boys
Acta Paediatrica
DOI: 10.1111/j.1651-2227.1979.tb05062.x
09/1979Automation of steroid radioimmunoassays for clinical and research purposes
Journal of Steroid Biochemistry
R. Vihko and G.L. Hammond
DOI: 10.1016/0022-4731(79)90286-3
07/1979The hormonal status of patients with benign prostatic hypertrophy: FSH, LH, TSH and prolactin responses to releasing hormones
Clinical Endocrinology
DOI: 10.1111/j.1365-2265.1979.tb02113.x
06/1979Serum steroids and pituitary hormones in infants with particular reference to testicular activity
Journal of Clinical Endocrinology and Metabolism
Hammond, G.L. and Koivisto, M. and Kouvalainen, K. and Vihko, R.
DOI: 10.1210/jcem-49-1-40
1979Discrete modular system for automation of radioimmunoassay of serum choriomammotropin
Clinical Chemistry
Hammond, G.L. and Leinonen, P. and Vihko, R.
DOI: 10.1093/clinchem/25.1.129
1979The concentration of six steroids in human testis after polyestradiolphosphate (Estradurin®) treatment of prostatic carcinoma
Acta Endocrinologica, Supplement
Leinonen, P. and Hammond, G.L. and Vihko, R.
1979A method for identification and follow-up of patients with a steroid-21-hydroxylase deficiency
Clinica Chimica Acta
S{\"o}lyom, J. and Hammond, G.L. and Vihko, R.
DOI: 10.1016/0009-8981(79)90104-9
1979Testicular steroid secretion and peripheral serum steroid concentrations in patients with prostatic carcinoma after short-term estrogen treatment
Investigative Urology
Lukkarinen, O. and Hammond, G.L. and Kontturi, M. and Vihko, R.
1979Serum sex hormone binding globulin and testosterone binding after estradiol administration, castration, and their combination in men with prostatic carcinoma
Investigative Urology
Leinonen, P. and Hammond, G.L. and Lukkarinen, O. and Vihko, R.
1979Serum steroids in normal males and patients with prostatic diseases
Clinical Endocrinology
DOI: 10.1111/j.1365-2265.1978.tb02189.x
08/1978Endogenous steroid levels in the human prostate from birth to old age: a comparison of normal and diseased tissues
Journal of Endocrinology
DOI: 10.1677/joe.0.0780007
07/1978The Radioimmunoassay of Testosterone, 5a-Dihydrotestosterone and Their Precursors in the Human Testis
International Journal of Andrology
G. L. Hammond and V. Ahonen and R. Vihko
DOI: 10.1111/j.1365-2605.1978.tb00031.x
06/1978The Simultaneous Radioimmunoassay of Seven Steroids in Human Spermatic and Peripheral Venous Blood
The Journal of Clinical Endocrinology & Metabolism
G. L. HAMMOND and A. RUOKONEN and M. KONTTURI and E. KOSKELA and R. VIHKO
DOI: 10.1210/jcem-45-1-16
07/1977Spermatic vein steroids,PROC. V. INT. CONGR. ENDOCRINOLOGY, VOL. I
EXCERPTA MEDICA, AMSTERDAM, ICS
Vihko, R. and Hammond, G.
1977Endogenous levels of eight steroids in the human prostate from birth to old age [proceedings]
Journal of Endocrinology
Hammond, G.L.
1977Automation of radioimmunoassays for some sex steroids with use of both iodinated and tritiated ligands
Clinical Chemistry
Hammond, G.L. and Viinikka, L. and Vihko, R.
DOI: 10.1093/clinchem/23.7.1250
1977SERUM FSH, LH AND PROLACTIN IN NORMAL MALES AND PATIENTS WITH PROSTATIC DISEASES
Clinical Endocrinology
HAMMOND, G.L. and KONTTURI, M. and M{\"A}{\"A}TT{\"A}L{\"A}, P. and PUUKKA, M. and VIHKO, R.
DOI: 10.1111/j.1365-2265.1977.tb01304.x
1977Metal–androgen interrelationships in carcinoma and hyperplasia of the human prostate
Journal of Endocrinology
DOI: 10.1677/joe.0.0710133
10/1976Proceedings: Testosterone, dihydrotestosterone, zinc and cadmium in prostatic tissue.
Journal of Endocrinology
Habib, F.K. and Hammond, G.L. and Stitch, S.R. and Dawson, J.B.
1975
Dr. Wendy Robinson awarded the 2023 Geoffrey L. Hammond Lectureship
Dr. Wendy Robinson has been awarded the 2023 Geoffrey L. Hammond Lectureship in recognition of her leadership and significant contributions to our understanding of genetic and epigenetic variation in prenatal development, as well as her passion and dedication to teaching and mentorship.