Geoffrey L. Hammond

PhD, MSc, BSc

Affiliate Investigator, BC Children's Hospital
Tier I Canada Research Chair, Reproductive Health

Steroid hormones control a wide range of normal biological processes but are also implicated in several disease processes including reproductive disorders, inflammation, diabetes, cardiovascular disease, and hormone-dependent cancers of male and female reproductive tissues. Synthetic steroids that act as agonists or antagonists are used widely as pharmacologic agents. The way steroids gain access to their target tissues is poorly understood. However, access is influenced primarily by two high affinity steroid-binding proteins in the blood: corticosteroid binding globulin (CBG) and sex hormone-binding globulin (SHBG). These two plasma proteins bind the glucocorticoids and sex steroids, respectively. By applying a combination of molecular biological, biochemical and physiological approaches we have gained new information about how CBG and SHBG are produced and function with respect to normal development and aging, and how they are involved in disease processes.

Academic Affiliations

  • Professor Emeritus/a, , Department of Cellular and Physiological Sciences, Faculty of Medicine, University of British Columbia
  • Research Theme: Healthy Starts

Contact Information

Location

2350 Health Science Mall, Unit 1340, UBC Faculty of Medicine, Dept of Cellular & Physiological Sciences, Vancouver, BC, Canada, V6T 1Z3

The NE/AAT/CBG axis regulates adipose tissue glucocorticoid exposure

Nature Communications

Boyle, L.D. and Miguelez-Crespo, A. and Paul, M. and Villalobos, E. and Toews, J.N.C. and Ivatt, L. and Nagy, B. and Magennis, M. and Homer, N.Z.M. and Andrew, R. and Viau, V. and Hammond, G.L. and Stimson, R.H. and Walker, B.R. and Nixon, M.

DOI: 10.1038/s41467-024-55693-x

Evolution of sex hormone-binding globulin gene expression in the primate testis

bioRxiv

Meyers, W.M. and Hammond, G.L.

DOI: 10.1101/2024.08.05.606716

Corticosteroid-Binding Globulin (SERPINA6) Consolidates Sexual Dimorphism of Adult Rat Liver

Endocrinology (United States)

Toews, J.N.C. and Philippe, T.J. and Dordevic, M. and Hill, L.A. and Hammond, G.L. and Viau, V.

DOI: 10.1210/endocr/bqad179

Characterization and comparison of recombinant full-length ursine and human sex hormone-binding globulin

FEBS Open Bio

Anne Mette Frbert and Malene Brohus and Julia N. C. Toews and Phillip Round and Ole Frbert and Geoffrey L. Hammond and Michael T. Overgaard

DOI: 10.1002/2211-5463.13341

02 / 2022

Corticosteroid-binding Globulin (SERPINA6) Establishes Postpubertal Sex Differences in Rat Adrenal Development

Endocrinology (United States)

Toews, J.N.C. and Philippe, T.J. and Hill, L.A. and Dordevic, M. and Miguelez-Crespo, A. and Homer, N.Z.M. and Nixon, M. and Hammond, G.L. and Viau, V.

DOI: 10.1210/endocr/bqac152

Differential Changes in Circulating Steroid Hormones in Hibernating Brown Bears: Preliminary Conclusions and Caveats

Physiological and Biochemical Zoology

Fr?bert, A.M. and Toews, J.N.C. and Nielsen, C.G. and Brohus, M. and Kindberg, J. and Jessen, N. and Fr{\"o}bert, O. and Hammond, G.L. and Overgaard, M.T.

DOI: 10.1086/721154

Homozygous SHBG Variant (rs6258) Linked to Gonadotropin-Independent Precocious Puberty in a Young Girl

Journal of the Endocrine Society

Victoria C Andriessen and Marissa Lightbourne and Chelsi Flippo and Fabio R Faucz and Angela Delaney and Fady Hannah-Shmouni and Geoffrey L Hammond and Constantine A Stratakis

DOI: 10.1210/jendso/bvab125

10 / 2021

Liver at the nexus of rat postnatal HPA axis maturation and sexual dimorphism.

The Journal of endocrinology

Toews JNC and Hammond GL and Viau V

DOI: 10.1530/joe-20-0286 PubMed: 33112814

01 / 2021

Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally-Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN): A Healthy Life Trajectories Initiative (HeLTI) Study

BMJ Open

Kumaran, K. and Krishnaveni, G.V. and Suryanarayana, K.G. and Prasad, M.P. and Belavendra, A. and Atkinson, S. and Balasubramaniam, R. and Bandsma, R.H.J. and Bhutta, Z.A. and Chandak, G.R. and Comelli, E.M. and Davidge, S.T. and Dennis, C.-L. and Hammond, G.L. and Jha, P. and Joseph, K.S. and Joshi, S.R. and Krishna, M. and Lee, K. and Lye, S. and McGowan, P. and Nepomnaschy, P. and Padvetnaya, V. and Pyne, S. and Sachdev, H.S. and Sahariah, S.A. and Singhal, N. and Trasler, J. and Yajnik, C.S. and Baird, J. and Barker, M. and Martin, M.-C. and Husain, N. and Sellen, D. and Fall, C.H.D. and Shah, P.S. and Matthews, S.G.

DOI: 10.1136/bmjopen-2020-045862

Spotted hyaenas and the sexual spectrum: reproductive endocrinology and development.

The Journal of endocrinology

Conley A and Place NJ and Legacki EL and Hammond GL and Cunha GR and Drea CM and Weldele ML and Glickman SE

DOI: 10.1530/joe-20-0252 PubMed: 32755997

10 / 2020

SUN-221 Subclinical Alpha-1 Antitrypsin Deficiency Is Associated with Increased Free Cortisol Fraction in Plasma and Altered Glucocorticoid Delivery to Tissues.

Journal of the Endocrine Society

Boyle LD and Nixon M and Underhill CM and Hill LA and Homer NZM and Andrew R and Hammond GL and Lewis JG and Stimson RH and Walker BR

05 / 2020

Molecular interactions between sex hormone"binding globulin and nonsteroidal ligands that enhance androgen activity

Journal of Biological Chemistry

Phillip Round and Samir Das and Tsung-Sheng Wu and Kristiina Whl and Filip Van Petegem and Geoffrey L. Hammond

DOI: 10.1016/S0021-9258(17)49880-2

01 / 2020

Molecular interactions between sex hormone" binding globulin and nonsteroidal ligands that enhance androgen activity

Journal of Biological Chemistry

Round, P. and Das, S. and Wu, T.-S. and Whl, K. and van Petegem, F. and Hammond, G.L.

DOI: 10.1074/jbc.RA119.011051

STEROIDS IN NORMAL AND DISEASED HUMAN PROSTATIC TISSUE

Hormones in Normal and Abnormal Human Tissues: Volume 1

Vihko, R. and Bolton, N. and Hammond, G.L. and Lahtonen, R.

DOI: 10.1515/9783111447001-023

Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression

Archives of Women's Mental Health

Pawluski, J.L. and Brain, U. and Hammond, G.L. and Oberlander, T.F.

DOI: 10.1007/s00737-018-0931-1

Sex hormone binding globulin during an annual reproductive cycle in the hepatopancreas and ovary of pejerrey (Odontesthes bonariensis)

General and Comparative Endocrinology

Gonzlez, A. and Fernandino, J.I. and Elisio, M. and Chalde, T. and Miranda, L.A. and Hammond, G.L. and Somoza, G.M.

DOI: 10.1016/j.ygcen.2018.11.010

N-glycosylation influences human corticosteroid-binding globulin measurements

Endocrine Connections

Hill, L.A. and Sumer-Bayraktar, Z. and Lewis, J.G. and Morava, E. and Thaysen-Andersen, M. and Hammond, G.L.

DOI: 10.1530/EC-19-0242

Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam

Behavioural Brain Research

Gemmel, M. and Harmeyer, D. and Bgi, E. and Fillet, M. and Hill, L.A. and Hammond, G.L. and Charlier, T.D. and Pawluski, J.L.

DOI: 10.1016/j.bbr.2017.11.038

Roles of plasma binding proteins in modulation of hormone action and metabolism

Encyclopedia of Endocrine Diseases

Hammond, G.L. and Hill, L.A. and Round, P.W.

DOI: 10.1016/B978-0-12-801238-3.64186-7

Human sex hormone-binding globulin does not provide metabolic protection against diet-induced obesity and dysglycemia in mice

Endocrine Connections

Sofer, Y. and Nevo, N. and Vechoropoulos, M. and Shefer, G. and Osher, E. and Landis, N. and Tordjman, K. and Hammond, G.L. and Stern, N.

DOI: 10.1530/EC-17-0240

The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester

BMC Medicine

Johnston, Z.C. and Bellingham, M. and Filis, P. and Soffientini, U. and Hough, D. and Bhattacharya, S. and Simard, M. and Hammond, G.L. and King, P. and O'Shaughnessy, P.J. and Fowler, P.A.

DOI: 10.1186/s12916-018-1009-7

Neutrophil elastase-cleaved corticosteroid-binding globulin is absent in human plasma

Journal of Endocrinology

Hill, L.A. and Vassiliadi, D.A. and Dimopoulou, I. and Anderson, A.J. and Boyle, L.D. and Kilgour, A.H.M. and Stimson, R.H. and Machado, Y. and Overall, C.M. and Walker, B.R. and Lewis, J.G. and Hammond, G.L.

DOI: 10.1530/JOE-18-0479

Erratum: Author Correction: Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: a new Contribution to the French Paradox (Scientific reports (2017) 7 1 (12284))

Scientific reports

Saez-Lopez, C. and Brianso-Llort, L. and Torres-Torronteras, J. and Sim, R. and Hammond, G.L. and Selva, D.M.

DOI: 10.1038/s41598-018-23159-y

Functional implications of corticosteroid-binding globulin N-glycosylation

Journal of Molecular Endocrinology

Simard, M. and Underhill, C. and Hammond, G.L.

DOI: 10.1530/JME-17-0234

Neutrophil elastase-mediated regulation of adipose glucocorticoid exposure through CBG cleavage

Endocrine Abstracts

Mark Nixon and Lesley Hill and Caroline Underhill and Geoffrey Hammond and Brian Walker

DOI: 10.1530/endoabs.50.oc3.4

10 / 2017

Long-Term Consequences of Extended Endocrine Strategies for Premenopausal Breast Cancer [11OP]

Obstetrics & Gynecology

Janice S. Kwon and Gary Pansegrau and Melica Nourmoussavi and Geoffrey Hammond and Mark Carey

DOI: 10.1097/01.aog.0000513940.92490.68

05 / 2017

Sex hormone binding globulin: Expression throughout early development and adult pejerrey fish, Odontesthes bonariensis

General and Comparative Endocrinology

Gonzlez, A. and Fernandino, J.I. and Hammond, G.L. and Somoza, G.M.

DOI: 10.1016/j.ygcen.2017.02.004

Resveratrol Increases Hepatic SHBG Expression through Human Constitutive Androstane Receptor: A new Contribution to the French Paradox

Scientific Reports

Saez-Lopez, C. and Brianso-Llort, L. and Torres-Torrenteras, J. and Sim, R. and Hammond, G.L. and Selva, D.M.

DOI: 10.1038/s41598-017-12509-x

Costs and benefits of extended endocrine strategies for premenopausal breast cancer

JNCCN Journal of the National Comprehensive Cancer Network

Kwon, J.S. and Pansegrau, G. and Nourmoussavi, M. and Hammond, G.L. and Carey, M.S.

DOI: 10.6004/jnccn.2017.0136

Sex hormone-binding globulin and the metabolic syndrome

Contemporary Endocrinology

Hammond, G.L.

DOI: 10.1007/978-3-319-53298-1_15

Perinatal fluoxetine effects on social play, the HPA system, and hippocampal plasticity in pre-adolescent male and female rats: Interactions with pre-gestational maternal stress

Psychoneuroendocrinology

Gemmel, M. and Hazlett, M. and Bgi, E. and De Lacalle, S. and Hill, L.A. and Kokras, N. and Hammond, G.L. and Dalla, C. and Charlier, T.D. and Pawluski, J.L.

DOI: 10.1016/j.psyneuen.2017.07.480

Ovarian ablation for premenopausal breast cancer: A review of treatment considerations and the impact of premature menopause

Cancer Treatment Reviews

Nourmoussavi, M. and Pansegrau, G. and Popesku, J. and Hammond, G.L. and Kwon, J.S. and Carey, M.S.

DOI: 10.1016/j.ctrv.2017.02.005

Control of androgen bioactivity by sex hormone-binding globulin

Endocrine Abstracts

Michael R Laurent and Leen Antonio and Marco H Blokland and Saskia S Sterk and Ferran Jardi and V Dubois and Jean-Mark Kaufman and Tom Fiers and Ilpo T Huhtaniemi and Geoffrey T. Hammond and Dirk Vanderschueren and Frank Claessens

DOI: 10.1530/endoabs.42.oc2

09 / 2016

Corticosteroid-binding globulin is a biomarker of inflammation onset and severity in female rats

Journal of Endocrinology

Hill, L.A. and Bodnar, T.S. and Weinberg, J. and Hammond, G.L.

DOI: 10.1530/JOE-16-0047

Plasma steroid-binding proteins: Primary gatekeepers of steroid hormone action

Journal of Endocrinology

Hammond, G.L.

DOI: 10.1530/JOE-16-0070

Effects of sex hormone-binding globulin (SHBG) on androgen bioactivity invitro

Molecular and Cellular Endocrinology

Laurent, M.R. and Helsen, C. and Antonio, L. and Schollaert, D. and Joniau, S. and Vos, M.J. and Decallonne, B. and Hammond, G.L. and Vanderschueren, D. and Claessens, F.

DOI: 10.1016/j.mce.2016.08.041

Long-term consequences of ovarian ablation for premenopausal breast cancer

Breast Cancer Research and Treatment

Kwon, J.S. and Pansegrau, G. and Nourmoussavi, M. and Hammond, G. and Carey, M.S.

DOI: 10.1007/s10549-016-3842-8

Identification of avian corticosteroid-binding globulin (SerpinA6) reveals the molecular basis of evolutionary adaptations in SerpinA6 structure and function as a steroid-binding protein

Journal of Biological Chemistry

Vashchenko, G. and Das, S. and Moon, K.-M. and Rogalski, J.C. and Taves, M.D. and Soma, K.K. and Van Petegem, F. and Foster, L.J. and Hammond, G.L.

DOI: 10.1074/jbc.M116.714378

Sex hormone-binding globulin regulation of androgen bioactivity in vivo: Validation of the free hormone hypothesis

Scientific Reports

Laurent, M.R. and Hammond, G.L. and Blokland, M. and Jard, F. and Antonio, L. and Dubois, V. and Khalil, R. and Sterk, S.S. and Gielen, E. and Decallonne, B. and Carmeliet, G. and Kaufman, J.-M. and Fiers, T. and Huhtaniemi, I.T. and Vanderschueren, D. and Claessens, F.

DOI: 10.1038/srep35539

Controlling the freedom of steroids in health and disease

Endocrine Abstracts

Geoffrey Hammond

DOI: 10.1530/endoabs.38.pl9

10 / 2015

Plasma corticosteroid-binding globulin: biomarker of inflammation onset and severity in a rat arthritis model

Endocrine Abstracts

Lesley Hill and Tamara Bodner and Joanne Weinberg and Geoffrey Hammond

DOI: 10.1530/endoabs.38.p387

10 / 2015

Society for Endocrinology International Medal Lecture

Endocrine Abstracts

Geoffrey Hammond

DOI: 10.1530/endoabs.38.pl9biog

10 / 2015

Naturally occurring mutations of human corticosteroid-binding globulin

Journal of Clinical Endocrinology and Metabolism

Simard, M. and Hill, L.A. and Lewis, J.G. and Hammond, G.L.

DOI: 10.1210/jc.2014-3130

Colony-specific differences in endocrine and immune responses to an inflammatory challenge in female Sprague Dawley rats

Endocrinology

Bodnar, T.S. and Hill, L.A. and Taves, M.D. and Yu, W. and Soma, K.K. and Hammond, G.L. and Weinberg, J.

DOI: 10.1210/en.2015-1497

Somatostatin is essential for the sexual dimorphism of gh secretion, corticosteroid-binding globulin production, and corticosterone levels in mice

Endocrinology

Adams, J.M. and Otero-Corchon, V. and Hammond, G.L. and Veldhuis, J.D. and Qi, N. and Low, M.J.

DOI: 10.1210/en.2014-1429

Impact of corticosteroid-binding globulin deficiency on pregnancy and neonatal sex

Journal of Clinical Endocrinology and Metabolism

Lei, J.-H. and Yang, X. and Peng, S. and Li, Y. and Underhill, C. and Zhu, C. and Lin, H.-Y. and Wang, H. and Hammond, G.L.

DOI: 10.1210/jc.2014-4254

Pseudomonas aeruginosa elastase disrupts the cortisol-binding activity of corticosteroid-binding globulin

Endocrinology

Simard, M. and Hill, L.A. and Underhill, C.M. and Keller, B.O. and Villanueva, I. and Hancock, R.E.W. and Hammond, G.L.

DOI: 10.1210/en.2014-1055

Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin

PLoS Genetics

Bolton, J.L. and Hayward, C. and Direk, N. and Lewis, J.G. and Hammond, G.L. and Hill, L.A. and Anderson, A. and Huffman, J. and Wilson, J.F. and Campbell, H. and Rudan, I. and Wright, A. and Hastie, N. and Wild, S.H. and Velders, F.P. and Hofman, A. and Uitterlinden, A.G. and Lahti, J. and Rikknen, K. and Kajantie, E. and Widen, E. and Palotie, A. and Eriksson, J.G. and Kaakinen, M. and Jrvelin, M.-R. and Timpson, N.J. and Davey Smith, G. and Ring, S.M. and Evans, D.M. and St Pourcain, B. and Tanaka, T. and Milaneschi, Y. and Bandinelli, S. and Ferrucci, L. and van der Harst, P. and Rosmalen, J.G.M. and Bakker, S.J.L. and Verweij, N. and Dullaart, R.P.F. and Mahajan, A. and Lindgren, C.M. and Morris, A. and Lind, L. and Ingelsson, E. and Anderson, L.N. and Pennell, C.E. and Lye, S.J. and Matthews, S.G. and Eriksson, J. and Mellstrom, D. and Ohlsson, C. and Price, J.F. and Strachan, M.W.J. and Reynolds, R.M. and Tiemeier, H. and Walker, B.R.

DOI: 10.1371/journal.pgen.1004474

Naturally occurring mutants inform SHBG structure and function

Molecular Endocrinology

Wu, T.-S. and Hammond, G.L.

DOI: 10.1210/me.2014-1058

Development of the external genitalia: Perspectives from the spotted hyena (Crocuta crocuta)

Differentiation

Cunha, G.R. and Risbridger, G. and Wang, H. and Place, N.J. and Grumbach, M. and Cunha, T.J. and Weldele, M. and Conley, A.J. and Barcellos, D. and Agarwal, S. and Bhargava, A. and Drea, C. and Hammond, G.L. and Siiteri, P. and Coscia, E.M. and McPhaul, M.J. and Baskin, L.S. and Glickman, S.E.

DOI: 10.1016/j.diff.2013.12.003

Evolving utility of sex hormone-binding globulin measurements in clinical medicine

Current Opinion in Endocrinology, Diabetes and Obesity

Hammond, G.L. and Wu, T.-S. and Simard, M.

DOI: 10.1097/MED.0b013e328353732f

Ontogenesis of phase i hepatic drug metabolic enzymes in sheep

Reproduction, Fertility and Development

Pretheeban, M. and Hammond, G. and Bandiera, S. and Riggs, W. and Rurak, D.

DOI: 10.1071/RD11159

Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences

PLoS ONE

Gardill, B.R. and Vogl, M.R. and Lin, H.-Y. and Hammond, G.L. and Muller, Y.A.

DOI: 10.1371/journal.pone.0052759

Two different corticosteroid-binding globulin variants that lack cortisol-binding activity in a Greek woman

Journal of Clinical Endocrinology and Metabolism

Hill, L.A. and Vassiliadi, D.A. and Simard, M. and Pavlaki, A. and Perogamvros, I. and Hadjidakis, D. and Hammond, G.L.

DOI: 10.1210/jc.2012-2467

Rhox5 rules in an evolving saga of reproductive diversity.

Biology of reproduction

Hammond, G.L.

DOI: 10.1095/biolreprod.112.101402

Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function

Psychoneuroendocrinology

Pawluski, J.L. and Brain, U.M. and Underhill, C.M. and Hammond, G.L. and Oberlander, T.F.

DOI: 10.1016/j.psyneuen.2011.11.011

Phylogenetic comparisons implicate sex hormone-binding globulin in "masculinization" of the female spotted hyena (Crocuta crocuta)

Endocrinology

Hammond, G.L. and Miguel-Queralt, S. and Yalcinkaya, T.M. and Underhill, C. and Place, N.J. and Glickman, S.E. and Drea, C.M. and Wagner, A.P. and Siiteri, P.K.

DOI: 10.1210/en.2011-1837

High frequency of SERPINA6 polymorphisms that reduce plasma corticosteroid-binding globulin activity in Chinese subjects

Journal of Clinical Endocrinology and Metabolism

Lin, H.-Y. and Underhill, C. and Lei, J.-H. and Helander-Claesson, A. and Lee, H.-Y. and Gardill, B.R. and Muller, Y.A. and Wang, H. and Hammond, G.L.

DOI: 10.1210/jc.2011-3141

Serum free estradiol and estrogen receptor-a mediated activity are related to decreased incident hip fractures in older women

Bone

Lim, V.W. and Li, J. and Gong, Y. and Yuan, J.-M. and Wu, T.S. and Hammond, G.L. and Jin, A. and Koh, W.-P. and Yong, E.L.

DOI: 10.1016/j.bone.2012.03.006

Selective cleavage of human sex hormone-binding globulin by kallikrein-related peptidases and effects on androgen action in LNCaP prostate cancer cells

Endocrinology

Sanchez, W.Y. and De Veer, S.J. and Swedberg, J.E. and Hong, E.-J. and Reid, J.C. and Walsh, T.P. and Hooper, J.D. and Hammond, G.L. and Clements, J.A. and Harris, J.M.

DOI: 10.1210/en.2012-1011

Fathead Minnow Sex Hormone-binding Globulin as Tool for Ecotoxicology Assessment.

Biology of Reproduction

Jason T. Popesku and Vicki L. Marlatt and Geoffrey L. Hammond

DOI: 10.1093/biolreprod/85.s1.289

07 / 2011

FoxA2 Mediates Monosaccharide-Induced Repression of SHBG Gene Expression by Regulating Lipid Homeostasis in HepG2 Cells.

Biology of Reproduction

Tsung-Sheng Wu and Geoffrey L. Hammond

DOI: 10.1093/biolreprod/85.s1.622

07 / 2011

When an Egg Is Not an Egg: Compromised Maternal mRNA Storage and Stabilization

Biology of Reproduction

M. Conti

DOI: 10.1095/biolreprod.111.094102

06 / 2011

37-kDa Laminin Receptor Precursor Mediates GnRH-II"Induced MMP-2 Expression and Invasiveness in Ovarian Cancer Cells

Molecular Endocrinology

Song Ling Poon and Christian Klausen and Geoffrey L. Hammond and Peter C. K. Leung

DOI: 10.1210/me.2010-0334

02 / 2011

(Arene)Cl2Ru(II) complexes with N-coordinated estrogen and androgen isonicotinates: Interaction with sex hormone binding globulin and anticancer activity

Steroids

Schobert, R. and Seibt, S. and Effenberger-Neidnicht, K. and Underhill, C. and Biersack, B. and Hammond, G.L.

DOI: 10.1016/j.steroids.2010.12.009

Diverse roles for sex hormone-binding globulin in reproduction

Biology of Reproduction

Hammond, G.L.

DOI: 10.1095/biolreprod.111.092593

Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via -catenin signaling in ovarian cancer cells

Endocrinology

Poon, S.L. and Lau, M.-T. and Hammond, G.L. and Leung, P.C.K.

DOI: 10.1210/en.2010-0942

Genetic determinants of serum testosterone concentrations in men

PLoS Genetics

Ohlsson, C. and Wallaschofski, H. and Lunetta, K.L. and Stolk, L. and Perry, J.R.B. and Koster, A. and Petersen, A.-K. and Eriksson, J. and Lehtimki, T. and Huhtaniemi, I.T. and Hammond, G.L. and Maggio, M. and Coviello, A.D. and Emas Study Group and Ferrucci, L. and Heier, M. and Hofman, A. and Holliday, K.L. and Jansson, J.-O. and Khnen, M. and Karasik, D. and Karlsson, M.K. and Kiel, D.P. and Liu, Y. and Ljunggren, O. and Lorentzon, M. and Lyytikinen, L.-P. and Meitinger, T. and Mellstrm, D. and Melzer, D. and Miljkovic, I. and Nauck, M. and Nilsson, M. and Penninx, B. and Pye, S.R. and Vasan, R.S. and Reincke, M. and Rivadeneira, F. and Tajar, A. and Teumer, A. and Uitterlinden, A.G. and Ulloor, J. and Viikari, J. and Vlker, U. and Vlzke, H. and Wichmann, H.E. and Wu, T.-S. and Zhuang, W.V. and Ziv, E. and Wu, F.C.W. and Raitakari, O. and Eriksson, A. and Bidlingmaier, M. and Harris, T.B. and Murray, A. and de Jong, F.H. and Murabito, J.M. and Bhasin, S. and Vandenput, L. and Haring, R.

DOI: 10.1371/journal.pgen.1002313

Ontogenesis of UDP-glucuronosyltransferase enzymes in sheep

Comparative Biochemistry and Physiology - A Molecular and Integrative Physiology

Pretheeban, M. and Hammond, G. and Bandiera, S. and Riggs, W. and Rurak, D.

DOI: 10.1016/j.cbpa.2011.02.014

Cytoplasmic accumulation of incompletely glycosylated shbg enhances androgen action in proximal tubule epithelial cells

Molecular Endocrinology

Hong, E.-J. and Sahu, B. and Jnne, O.A. and Hammond, G.L.

DOI: 10.1210/me.2010-0483

Molecular and Cellular Endocrinology. Foreward.

Molecular and cellular endocrinology

Hammond, G.L.

Molecular and structural basis of steroid hormone binding and release from corticosteroid-binding globulin

Molecular and Cellular Endocrinology

Lin, H.-Y. and Muller, Y.A. and Hammond, G.L.

DOI: 10.1016/j.mce.2009.06.015

Gonadotropin-releasing hormone-I-mediated activation of progesterone receptor contributes to gonadotropin a-subunit expression in mouse gonadotrophs

Endocrinology

Chen, J. and An, B.-S. and So, W.-K. and Cheng, L. and Hammond, G.L. and Leung, P.C.K.

DOI: 10.1210/en.2009-0816

Foreward

Molecular and Cellular Endocrinology

Hammond, G.L.

DOI: 10.1016/j.mce.2009.09.015

Structural analyses of sex hormone-binding globulin reveal novel ligands and function

Molecular and Cellular Endocrinology

Avvakumov, G.V. and Cherkasov, A. and Muller, Y.A. and Hammond, G.L.

DOI: 10.1016/j.mce.2009.09.005

Novel corticosteroid-binding globulin variant that lacks steroid binding activity

Journal of Clinical Endocrinology and Metabolism

Perogamvros, I. and Underhill, C. and Henley, D.E. and Hadfield, K.D. and Newman, W.G. and Ray, D.W. and Lightman, S.L. and Hammond, G.L. and Trainer, P.J.

DOI: 10.1210/jc.2010-0746

In silico identification of anthropogenic chemicals as ligands of zebrafish sex hormone binding globulin

Toxicology and Applied Pharmacology

Thorsteinson, N. and Ban, F. and Santos-Filho, O. and Tabaei, S.M.H. and Miguel-Queralt, S. and Underhill, C. and Cherkasov, A. and Hammond, G.L.

DOI: 10.1016/j.taap.2008.07.014

Effects of aggressive encounters on plasma corticosteroid-binding globulin and its ligands in white-crowned sparrows

Hormones and Behavior

Charlier, T.D. and Underhill, C. and Hammond, G.L. and Soma, K.K.

DOI: 10.1016/j.yhbeh.2009.06.012

Characterization and Measurement of the Plasma a- and -Sex Hormone-Binding Globulin Paralogs in Salmon

Endocrinology

Miguel-Queralt, S. and Underhill, C. and Devlin, R.H. and Hammond, G.L.

DOI: 10.1210/en.2008-0964

Thyroid hormones act indirectly to increase sex hormone-binding globulin production by liver via hepatocyte nuclear factor-4a

Journal of Molecular Endocrinology

Selva, D.M. and Hammond, G.L.

DOI: 10.1677/JME-09-0025

Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-a contributes to fosB expression in mouse gonadotrophs

Endocrinology

Chen, J. and An, B.-S. and Cheng, L. and Hammond, G.L. and Leung, P.C.K.

DOI: 10.1210/en.2009-0455

Reproductive experience alters corticosterone and CBG levels in the rat dam

Physiology and Behavior

Pawluski, J.L. and Charlier, T.D. and Lieblich, S.E. and Hammond, G.L. and Galea, L.A.M.

DOI: 10.1016/j.physbeh.2008.09.004

Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor

Biology of Reproduction

An, B.-S. and Song, L.P. and So, W.-K. and Hammond, G.L. and Leung, P.C.K.

DOI: 10.1095/biolreprod.109.076216

Residues in the human corticosteroid-binding globulin reactive center loop that influence steroid binding before and after elastase cleavage

Journal of Biological Chemistry

Lin, H.-Y. and Underhill, C. and Gardill, B.R. and Muller, Y.A. and Hammond, G.L.

DOI: 10.1074/jbc.M807376200

Peroxisome-proliferator receptor represses hepatic sex hormone-binding globulin expression

Endocrinology

Hammond, G.L. and Selva, D.M.

DOI: 10.1210/en.2008-1289

Two Forms of Sex Hormone-Binding Globulin in Salmonid Blood.

Biology of Reproduction

Solange Miguel-Queralt and Caroline Underhill and Geoffrey L. Hammond

DOI: 10.1093/biolreprod/78.s1.215c

05 / 2008

Estetrol does not bind sex hormone binding globulin or increase its production by human HepG2 cells

Climacteric

Hammond, G.L. and Hogeveen, K.N. and Visser, M. and Coelingh Bennink, H.J.T.

DOI: 10.1080/13697130701851814

Estrogen receptor a gene polymorphisms are associated with idiopathic premature ovarian failure

Fertility and Sterility

Bretherick, K.L. and Hanna, C.W. and Currie, L.M. and Fluker, M.R. and Hammond, G.L. and Robinson, W.P.

DOI: 10.1016/j.fertnstert.2007.03.008

Sex hormone-binding globulin in fish gills is a portal for sex steroids breached by xenobiotics

Endocrinology

Miguel-Queralt, S. and Hammond, G.L.

DOI: 10.1210/en.2008-0384

An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin

Journal of Medicinal Chemistry

Cherkasov, A. and Ban, F. and Santos-Filho, O. and Thorsteinson, N. and Fallahi, M. and Hammond, G.L.

DOI: 10.1021/jm7011485

Temporal recruitment of transcription factors at the 3',5'- cyclic adenosine 5'-monophosphate-response element of the human GnRH-II promoter

Endocrinology

Song, L.P. and An, B.-S. and So, W.-K. and Hammond, G.L. and Leung, P.C.K.

DOI: 10.1210/en.2008-0481

Monosaccharide-induced lipogenesis regulates the human hepatic sex hormone-binding globulin gene

Journal of Clinical Investigation

Selva, D.M. and Hogeveen, K.N. and Innis, S.M. and Hammond, G.L.

DOI: 10.1172/JCI32249

Steroid conjugates of dichloro(6-aminomethylnicotinate) platinum(II): Effects on DNA, sex hormone binding globulin, the estrogen receptor, and various breast cancer cell lines

ChemMedChem

Schobert, R. and Bernhardt, G. and Biersack, B. and Bollwein, S. and Fallahi, M. and Grotemeierd, A. and Hammond, G.L.

DOI: 10.1002/cmdc.200600173

Testicular degeneration in Huntington disease

Neurobiology of Disease

Van Raamsdonk, J.M. and Murphy, Z. and Selva, D.M. and Hamidizadeh, R. and Pearson, J. and Petersn, ?. and Bjrkqvist, M. and Muir, C. and Mackenzie, I.R. and Hammond, G.L. and Vogl, A.W. and Hayden, M.R. and Leavitt, B.R.

DOI: 10.1016/j.nbd.2007.01.006

Corticosteroid-binding Globulin, a Structural Basis for Steroid Transport and Proteinase-triggered Release

Journal of Biological Chemistry

Klieber, M.A. and Underhill, C. and Hammond, G.L. and Muller, Y.A.

DOI: 10.1074/jbc.M705014200

Sex hormone-binding globulin expression in sea bass (Dicentrarchus labrax L.) throughout development and the reproductive season

Molecular and Cellular Endocrinology

Miguel-Queralt, S. and Blzquez, M. and Piferrer, F. and Hammond, G.L.

DOI: 10.1016/j.mce.2007.06.009

Human Sex Hormone-binding Globulin is Expressed in Testicular Germ Cells and not in Sertoli Cells

Hormone and Metabolic Research

D. Selva and G. Hammond

DOI: 10.1055/s-2006-925336

04 / 2006

Do oral contraceptives produce irreversible effects on women's sexuality? [1]

Journal of Sexual Medicine

Bancroft, J. and Hammond, G. and Graham, C.

DOI: 10.1111/j.1743-6109.2006.00253.x

Evidence that fibulin family members contribute to the steroid-dependent extravascular sequestration of sex hormone-binding globulin

Journal of Biological Chemistry

Ng, K.-M. and Catalano, M.G. and Pins, T. and Selva, D.M. and Avvakumov, G.V. and Munell, F. and Hammond, G.L.

DOI: 10.1074/jbc.M512370200

SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density

Journal of Clinical Endocrinology and Metabolism

Eriksson, A.L. and Lorentzon, M. and Mellstrm, D. and Vandenput, L. and Swanson, C. and Andersson, N. and Hammond, G.L. and Jakobsson, J. and Rane, A. and Orwoll, E.S. and Ljunggren, . and Johnell, O. and Labrie, F. and Windahl, S.H. and Ohlsson, C.

DOI: 10.1210/jc.2006-0679

Progressive docking: A hybrid QSAR/docking approach for accelerating in silico high throughput screening

Journal of Medicinal Chemistry

Cherkasov, A. and Ban, F. and Li, Y. and Fallahi, M. and Hammond, G.L.

DOI: 10.1021/jm060961+

Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells

Journal of Biological Chemistry

An, B.-S. and Selva, D.M. and Hammond, G.L. and Rivero-Muller, A. and Rahman, N. and Leung, P.C.K.

DOI: 10.1074/jbc.M600743200

Human sperm sex hormone-binding globulin isoform: Characterization and measurement by time-resolved fluorescence immunoassay

Journal of Clinical Endocrinology and Metabolism

Selva, D.M. and Bassas, L. and Munell, F. and Mata, A. and Tekpetey, F. and Lewis, J.G. and Hammond, G.L.

DOI: 10.1210/jc.2005-1192

Successful in silico discovery of novel nonsteroidal ligands for human sex hormone binding globulin

Journal of Medicinal Chemistry

Cherkasov, A. and Shi, Z. and Fallahi, M. and Hammond, G.L.

DOI: 10.1021/jm049087f

'Inductive' charges on atoms in proteins: Comparative docking with the extended steroid benchmark set and discovery of a novel SHBG ligand

Journal of Chemical Information and Modeling

Cherkasov, A. and Shi, Z. and Li, Y. and Jones, S.J.M. and Fallahi, M. and Hammond, G.L.

DOI: 10.1021/ci0498158

Sea bass (Dicentrarchus labrax) sex hormone binding globulin: Molecular and biochemical properties and phylogenetic comparison of its orthologues in multiple fish species

Molecular and Cellular Endocrinology

Miguel-Queralt, S. and Avvakumov, G.V. and Blzquez, M. and Piferrer, F. and Hammond, G.L.

DOI: 10.1016/j.mce.2004.10.004

Repression of the human sex hormone-binding globulin gene in sertoli cells by upstream stimulatory transcription factors

Journal of Biological Chemistry

Selva, D.M. and Hogeveen, K.N. and Hammond, G.L.

DOI: 10.1074/jbc.M409616200

Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study

Breast Cancer Research

Hong, C.-C. and Tang, B.-K. and Hammond, G.L. and Tritchler, D. and Yaffe, M. and Boyd, N.F.

DOI: 10.1186/bcr798

The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility

Journal of Lipid Research

Selva, D.M. and Hirsch-Reinshagen, V. and Burgess, B. and Zhou, S. and Chan, J. and McIsaac, S. and Hayden, M.R. and Hammond, G.L. and Vogl, A.W. and Wellington, C.L.

DOI: 10.1194/jlr.M400007-JLR200

Molecular and functional characterization of sex hormone binding globulin in zebrafish

Endocrinology

Miguel-Queralt, S. and Knowlton, M. and Avvakumov, G.V. and Al-Nouno, R. and Kelly, G.M. and Hammond, G.L.

DOI: 10.1210/en.2004-0678

Association between the T27C polymorphism in the cytochrome P450 c17a (CYP17) gene and risk factors for breast cancer

Breast Cancer Research and Treatment

Hong, C.-C. and Thompson, H.J. and Jiang, C. and Hammond, G.L. and Tritchler, D. and Yaffe, M. and Boyd, N.F.

DOI: 10.1007/s10549-004-0780-7

Serum distribution of the major metabolites of norgestimate in relation to its pharmacological properties

Contraception

Hammond, G.L. and Abrams, L.S. and Creasy, G.W. and Natarajan, J. and Allen, J.G. and Siiteri, P.K.

DOI: 10.1016/S0010-7824(02)00473-0

Sex Hormone-Binding Globulin (SHBG)

Encyclopedia of Hormones

Geoffrey L. Hammond and Kevin N. Hogeveen

DOI: 10.1016/b0-12-341103-3/00269-2

Val158Met polymorphism in catechol-O-methyltransferase gene associated with risk factors for breast cancer

Cancer Epidemiology Biomarkers and Prevention

Hong, C.-C. and Thompson, H.J. and Jiang, C. and Hammond, G.L. and Tritchler, D. and Yaffe, M. and Boyd, N.F.

Structure/function analyses of human sex hormone-binding globulin: Effects of zinc on steroid-binding specificity

Journal of Steroid Biochemistry and Molecular Biology

Hammond, G.L. and Avvakumov, G.V. and Muller, Y.A.

DOI: 10.1016/S0960-0760(03)00195-X

Lack of effect of a low-fat high-carbohydrate diet on ovarian hormones in premenopausal women: results from a randomized trial.

IARC scientific publications

Boyd, N.F. and Greenberg, C. and Martin, L. and Stone, J. and Hammond, G. and Minkin, S. and Canadian Diet and Breast Cancer Prevention Study Group

The association of breast mitogens with mammographic densities

British Journal of Cancer

Boyd, N.F. and Stone, J. and Martin, L.J. and Jong, R. and Fishell, E. and Yaffe, M. and Hammond, G. and Minkin, S.

DOI: 10.1038/sj.bjc.6600537

Steroid ligands bind human sex hormone-binding globulin in specific orientations and produce distinct changes in protein conformation

Journal of Biological Chemistry

Grishkovskaya, I. and Avvakumov, G.V. and Hammond, G.L. and Catalano, M.G. and Muller, Y.A.

DOI: 10.1074/jbc.M203999200

Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction

Journal of Clinical Investigation

Hogeveen, K.N. and Cousin, P. and Pugeat, M. and Dewailly, D. and Soudan, B. and Hammond, G.L.

DOI: 10.1172/JCI0214060

Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site

Journal of Molecular Biology

Grishkovskaya, I. and Avvakumov, G.V. and Hammond, G.L. and Muller, Y.A.

DOI: 10.1016/S0022-2836(02)00169-9

Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol

Journal of Biological Chemistry

Avvakumov, G.V. and Grishkovskaya, I. and Muller, Y.A. and Hammond, G.L.

DOI: 10.1074/jbc.M207762200

Access of reproductive steroids to target tissues

Obstetrics and Gynecology Clinics of North America

Hammond, G.L.

DOI: 10.1016/S0889-8545(02)00008-6

O-Glycosylation of human sex hormone-binding globulin is essential for inhibition of estradiol-induced MCF-7 breast cancer cell proliferation

Molecular and Cellular Endocrinology

Raineri, M. and Catalano, M.G and Hammond, G.L and Avvakumov, G.V and Frairia, R. and Fortunati, N.

DOI: 10.1016/S0303-7207(01)00725-0

A human sex hormone-binding globulin isoform accumulates in the acrosome during spermatogenesis

Journal of Biological Chemistry

Selva, D.M. and Hogeveen, K.N. and Seguchi, K. and Tekpetey, F. and Hammond, G.L.

DOI: 10.1074/jbc.M205903200

18F-labeled difluoroestradiols: Preparation and preclinical evaluation as estrogen receptor-binding radiopharmaceuticals

Steroids

Seimbille, Y. and Rousseau, J. and Bnard, F. and Morin, C. and Ali, H. and Avvakumov, G. and Hammond, G.L. and van Lier, J.E.

DOI: 10.1016/S0039-128X(02)00025-9

Resolution of the Human Sex Hormone-binding Globulin Dimer Interface and Evidence for Two Steroid-binding Sites per Homodimer

Journal of Biological Chemistry

Avvakumov, G.V. and Grishkovskaya, I. and Muller, Y.A. and Hammond, G.L.

DOI: 10.1074/jbc.M106274200

Preclinical profiles of progestins used in formulations of oral contraceptives and hormone replacement therapy

American Journal of Obstetrics and Gynecology

Hammond, G.L. and Rabe, T. and Wagner, J.D.

DOI: 10.1067/mob.2001.117415

Human Sex Hormone-binding Globulin Promoter Activity Is Influenced by a (TAAAA)n Repeat Element within an Alu Sequence

Journal of Biological Chemistry

Hogeveen, K.N. and Talikka, M. and Hammond, G.L.

DOI: 10.1074/jbc.M104681200

Interactions between human plasma sex hormone-binding globulin and xenobiotic ligands

Journal of Steroid Biochemistry and Molecular Biology

Jury, H.H. and Zacharewski, T.R. and Hammond, G.L.

DOI: 10.1016/S0960-0760(00)00168-0

The rabbit sex hormone-binding globulin gene: Structural organization and characterization of its 5'-flanking region

Endocrinology

Ip, Y.-C. and Lee, W.M. and Hammond, G.L.

DOI: 10.1210/endo.141.4.7406

Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity

Journal of Clinical Endocrinology and Metabolism

Emptoz-Bonneton, A. and Cousin, P. and Seguchi, K. and Avvakumov, G.V. and Bully, C. and Hammond, G.L. and Pugeat, M.

DOI: 10.1210/jc.85.1.361

Crystal structure of human sex hormone-binding globulin: Steroid transport by a laminin G-like domain

EMBO Journal

Grishkovskaya, I. and Avvakumov, G.V. and Sklenar, G. and Dales, D. and Hammond, G.L. and Muller, Y.A.

DOI: 10.1093/emboj/19.4.504

Estrogen receptor- and aryl hydrocarbon receptor-mediated activities of a coal-tar creosote

Environmental Toxicology and Chemistry

Fielden, M.R. and Wu, Z.-F. and Sinal, C.J. and Jury, H.H. and Bend, J.R. and Hammond, G.L. and Zacharewski, T.R.

DOI: 10.1002/etc.5620190507

Steroid-binding specificity of human sex hormone-binding globulin is influenced by occupancy of a zinc-binding site

Journal of Biological Chemistry

Avvakumov, G.V. and Muller, Y.A. and Hammond, G.L.

DOI: 10.1074/jbc.M004484200

Crystallization of the N-terminal domain of human sex hormone-binding globulin, the major sex steroid carrier in blood

Acta Crystallographica Section D: Biological Crystallography

Grishkovskaya, I. and Sklenar, G. and Avvakumov, G.V. and Dales, D. and Behlke, J. and Hammond, G.L. and Muller, Y.A.

DOI: 10.1107/S0907444999012883

The SHBG gene and hormone dependence of breast cancer: A novel mechanism of hormone dependence of MCF-7 human breast cancer cells based upon SHBG

Breast Cancer

Murayama, Y. and Hammond, G.L. and Sugihara, K.

DOI: 10.1007/BF02966450

Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock

Genomics

Libert, Q. and Wielockx, B. and Hammond, G.L. and Brouckaert, P. and Rers, W. and Bliott, R.W.

DOI: 10.1006/geno.1998.5677

Influence of glycosylation on the clearance of recombinant human sex hormone-binding globulin from rabbit blood

Journal of Steroid Biochemistry and Molecular Biology

Cousin, P. and Dchaud, H. and Grenot, C. and Lejeune, H. and Hammond, G.L. and Pugeat, M.

DOI: 10.1016/S0960-0760(99)00101-6

Role of sex hormone-binding globulin in target uptake of radiolabelled steroids: Investigations in transgenic models

Journal of Labelled Compounds and Radiopharmaceuticals

Jonson, S.D. and Wang, J. and Hodgert Jury, H. and Tsvetnitsky, V. and Hammond, G.L. and Welch, M.J.

Expression and regulation of human sex hormone-binding globulin transgenes in mice during development

Endocrinology

Jnne, M. and Hogeveen, K.N. and Deol, H.K. and Hammond, G.L.

DOI: 10.1210/endo.140.9.7004

N-glycans are not the signal for apical sorting of corticosteroid binding globulin in MDCK cells

FEBS Letters

Larsen, J.E. and Avvakumov, G.V. and Hammond, G.L. and Vogel, L.K.

DOI: 10.1016/S0014-5793(99)00526-8

Establishment of a mouse Sertoli cell line producing rat androgen- binding protein (ABP)

Steroids

Ducray, A. and Bloquel, M. and Hess, K. and Hammond, G.L. and Grard, H. and Grard, A.

DOI: 10.1016/S0039-128X(98)00030-0

Hepatocyte nuclear factor-4 controls transcription from a TATA-less human sex hormone-binding globulin gene promoter

Journal of Biological Chemistry

Jnne, M. and Hammond, G.L.

DOI: 10.1074/jbc.273.51.34105

Human sex hormone-binding globulin gene expression in transgenic mice

Molecular Endocrinology

Jnne, M. and Deol, H.K. and Power, S.G.A. and Yee, S.-P. and Hammond, G.L.

DOI: 10.1210/mend.12.1.0050

Divergent changes in plasma ACTH and pituitary POMC mRNA after cortisol administration to late-gestation ovine fetus

American Journal of Physiology - Endocrinology and Metabolism

Jeffray, T.M. and Matthews, S.G. and Hammond, G.L. and Challis, J.R.G.

DOI: 10.1152/ajpendo.1998.274.3.e417

Control of the membrane sex hormone-binding globulin-receptor (SHBG-R) in MCF-7 cells: Effect of locally produced SHBG

Steroids

Fortunati, N. and Raineri, M. and Cignetti, A. and Hammond, G.L. and Frairia, R.

DOI: 10.1016/S0039-128X(98)00021-X

Effects of a low-fat high-carbohydrate diet on plasma sex hormones in premenopausal women: results from a randomized controlled trial

British Journal of Cancer

NF Boyd and for the Canadian Diet and Breast Cancer Prevention Study Group (See Appendix I) and GA Lockwood and CV Greenberg and LJ Martin and DL Tritchler

DOI: 10.1038/bjc.1997.348

07 / 1997

The effects of estradiol-17 infusion into fetal sheep in late gestation

Endocrine

Wang, S. and Matthews, S.G. and Jeffray, T.M. and Stevens, M.Y. and Yang, K. and Hammond, G.L. and Challis, J.R.G.

DOI: 10.1007/BF02820503

Rabbit sex hormone binding globulin: Primary structure, tissue expression, and structure/function analyses by expression in Escherichia coli

Journal of Endocrinology

Lee, W.M. and Wong, A.S.T. and Tu, A.W.K. and Cheung, C.-H. and Li, J.C.H. and Hammond, G.L.

DOI: 10.1677/joe.0.1530373

ABP sertolienne et synthese de l'adn dans les cellules germinales du rat et de la souris prepuberes

Andrologie

Gerard, A. and Clerc, A. and Adam, M. and Franck, P. and Nabet, F. and Closset, J. and Hammond, G. and Gerard, H.

Glucocorticoids induce corticosteroid-binding globulin biosynthesis by immature mouse liver and kidney

Journal of Steroid Biochemistry and Molecular Biology

Zhao, X.-F. and Scrocchi, L.A. and Hammond, G.L.

DOI: 10.1016/S0960-0760(96)00181-1

Determinants of steroid hormone bioavailability

Biochemical Society Transactions

Hammond, G.L.

DOI: 10.1042/bst0250577

Hepatic nuclear proteins that bind cis-regulatory elements in the proximal promoter of the rat corticosteroid-binding globulin gene

Molecular and Cellular Endocrinology

Zhao, X.-F. and Underhill, D.A. and Hammond, G.L.

DOI: 10.1016/S0303-7207(96)03992-5

Differential Effects of Betamethasone and Dexamethasone Fetal Administration of Parturition in Sheep

Journal of the Society for Gynecologic Investigation

Jan B. Derks and Dino A. Giussani and Lecia M. Van Dam and Susan L. Jenkins and James A. Winter and Xian F. Zhao and Geoffrey L. Hammond and Peter W. Nathanielsz

DOI: 10.1177/107155769600300607

11 / 1996

Murine corticosteroid binding globulin localizes to early embryo trophoblasts

Placenta

M.G. Baines and E. Antecka and G.L. Hammond

DOI: 10.1016/s0143-4004(96)90241-6

07 / 1996

Growth response of adult germ cells to rat androgen-binding protein and human sex hormone-binding globulin

Hormone Research in Paediatrics

Grard, A. and Bedjou, R. and Clerc, A. and Maachi, F. and Closset, J. and Hammond, G.L. and Nabet, F. and Grard, H.

DOI: 10.1159/000184791

Sex hormone-binding globulin: Gene organization and structure/function analyses

Hormone Research in Paediatrics

Hammond, G.L. and Bocchinfuso, W.P.

DOI: 10.1159/000184787

Developmental regulation of corticosteroid-binding globulin biosynthesis in the baboon fetus

Endocrinology

Pepe, G.J. and Jury, H.H. and Hammond, G.L. and Albrecht, E.D.

DOI: 10.1210/endo.137.8.8754758

Sex hormone-binding globulin/androgen-binding protein: Steroid-binding and dimerization domains

Journal of Steroid Biochemistry and Molecular Biology

Hammond, G.L. and Bocchinfuso, W.P.

DOI: 10.1016/0960-0760(95)00110-L

cis-Regulatory elements within the proximal promoter of the rat gene encoding corticosteroid-binding globulin

Gene

Underhill, D.A. and Hammond, G.L.

DOI: 10.1016/0378-1119(95)00337-6

Potential functions of plasma steroid-binding proteins

Trends in Endocrinology and Metabolism

Hammond, G.L.

DOI: 10.1016/1043-2760(95)00162-X

Corticosteroid-binding globulin (CBG) in fetal development

Journal of Steroid Biochemistry and Molecular Biology

Challis, J.R.G. and Berdusco, E.T.M. and Jeffray, T.M. and Yang, K. and Hammond, G.L.

DOI: 10.1016/0960-0760(95)00100-E

Resolution of the Steroid-Binding and Dimerization Domains of Human Sex Hormone-Binding Globulin by Expression in Escherichia Coli

Biochemistry

Hildebrand, C. and Bocchinfuso, W.P. and Dales, D. and Hammond, G.L.

DOI: 10.1021/bi00010a012

Corticosteroid-binding globulin (CBG) production by hepatic and extra-hepatic sites in the ovine fetus; effects of CBG on glucocorticoid negative feedback on pituitary cells in vitro

Journal of Endocrinology

Berdusco, E.T.M. and Yang, K. and Hammond, G.L. and Challis, J.R.G.

DOI: 10.1677/joe.0.1460121

Squirrel monkey corticosteroid-binding globulin: primary structure and comparison with the human protein

Endocrinology

G. L. Hammond

DOI: 10.1210/en.134.2.891

02 / 1994

Glycosylation of Human Corticosteroid-Binding Globulin. Differential Processing and Significance of Carbohydrate Chains at Individual Sites

Biochemistry

Avvakumov, G.V. and Hammond, G.L.

DOI: 10.1021/bi00185a012

Substitutions of tryptophan residues in human corticosteroid-binding globulin: Impact on steroid binding and glycosylation

Journal of Steroid Biochemistry and Molecular Biology

Avvakumov, G.V. and Hammond, G.L.

DOI: 10.1016/0960-0760(94)90010-8

Serum distribution of two contraceptive progestins: 3-ketodesogestrel and gestodene

Contraception

Hammond, G.L. and Bocchinfuso, W.P. and Orava, M. and Smith, C.L. and Van Den Ende, A. and Van Enk, A.

DOI: 10.1016/0010-7824(94)90018-3

Structure and chromosomal location of the gene encoding mouse corticosteroid-binding globulin: strain differences in coding sequence and steroid-binding activity

Gene

Orava, M. and Zhao, X.F. and Leiter, E. and Hammond, G.L.

DOI: 10.1016/0378-1119(94)90387-5

Steroid-Binding and Dimerization Domains of Human Sex Hormone-Binding Globulin Partially Overlap: Steroids and Ca2+ Stabilize Dimer Formation

Biochemistry

Bocchinfuso, W.P. and Hammond, G.L.

DOI: 10.1021/bi00201a008

Interleukin-6 inhibits corticosteroid-binding globulin synthesis by human hepatoblastoma-derived (Hep G2) cells.

Endocrinology

L Bartalena and G L Hammond and A Farsetti and I L Flink and J Robbins

DOI: 10.1210/endo.133.1.8391424

07 / 1993

Decreased cortisol-binding affinity of transcortin Leuven is associated with an amino acid substitution at residue-93

Steroids

Hugo Van Baelen and Stephen G.A. Power and Geoffrey L. Hammond

DOI: 10.1016/0039-128x(93)90072-u

06 / 1993

Spatial and temporal distribution of corticosteroid-binding globulin and its messenger ribonucleic acid in embryonic and fetal mice.

Endocrinology

L A Scrocchi and M Orava and C L Smith and V K Han and G L Hammond

DOI: 10.1210/endo.132.2.7916682

02 / 1993

Spatial and temporal distribution of corticosteroid-binding globulin and its messenger ribonucleic acid in embryonic and fetal mice

Endocrinology

Scrocchi, L.A. and Orava, M. and Smith, C.L. and Han, V.K.M. and Hammond, G.L.

Interleukin-6 inhibits corticosteroid-binding globulin synthesis by human hepatoblastoma-derived (Hep G2) cells

Endocrinology

Bartalena, L. and Hammond, G.L. and Farsetti, A. and Flink, I.L. and Robbins, J.

Tissue distribution of a1-proteinase inhibitor messenger ribonucleic acid and its regulation by glucocorticoids in fetal and neonatal sheep

Biology of Reproduction

Berdusco, E.T.M. and Yang, K. and Challis, J.R.G. and Hammond, G.L.

DOI: 10.1095/biolreprod49.4.816

Glucocorticoid-induced increase in plasma corticosteroid-binding globulin levels in fetal sheep is associated with increased biosynthesis and alterations in glycosylation

Endocrinology

Berdusco, E.T.M. and Hammond, G.L. and Jacobs, R.A. and Grolla, A. and Akagi, K. and Langlois, D. and Challis, J.R.G.

DOI: 10.1210/endo.132.5.8477651

Effect of burn injury on corticosteroid-binding globulin levels in plasma and wound fluid

Wound Repair and Regeneration

Garrel, D.R. and Zhang, L. and Zhao, X.?F. and Hammond, G.L.

DOI: 10.1046/j.1524-475X.1993.10105.x

Corticosteroid-binding globulin biosynthesis in the mouse liver and kidney during postnatal development

Endocrinology

Scrocchi, L.A. and Hearn, S.A. and Han, V.K.M. and Hammond, G.L.

DOI: 10.1210/endo.132.2.8425503

Physical mapping of four serpin genes: a1-antitrypsin, a1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome 14q32.1

American Journal of Human Genetics

Billingsley, G.D. and Walter, M.A. and Hammond, G.L. and Cox, D.W.

Glycosylation of human corticosteroid-binding globulin at aspargine 238 is necessary for steroid binding

Journal of Biological Chemistry

Avvakumov, G.V. and Warmels-Rodenhiser, S. and Hammond, G.L.

Cloning of an ovine 11-hydroxysteroid dehydrogenase complementary deoxyribonucleic acid: Tissue and temporal distribution of its messenger ribonucleic acid during fetal and neonatal development

Endocrinology

Yang, K. and Smith, C.L. and Dales, D. and Hammond, G.L. and Challis, J.R.G.

DOI: 10.1210/endo.131.5.1425412

Molecular analyses of a human sex hormone-binding globulin variant: Evidence for an additional carbohydrate chain

Journal of Clinical Endocrinology and Metabolism

Power, S.G.A. and Bocchinfuso, W.P. and Pallesen, M. and Warmels-Rodenhiser, S. and Baelen, H.V. and Hammond, G.L.

DOI: 10.1210/jcem.75.4.1400872

Structure/function analyses of human sex hormone-binding globulin by site-directed mutagenesis

FEBS Letters

Bocchinfuso, W.P. and Warmels-Rodenhiser, S. and Hammond, G.L.

DOI: 10.1016/0014-5793(92)81253-I

Hormonal regulation of corticosteroid-binding globulin biosynthesis in the male rat

Endocrinology

Smith, C.L. and Hammond, G.L.

DOI: 10.1210/endo.130.4.1547738

Characterization of an ovine glucocorticoid receptor cDNA and developmental changes in its mRNA levels in the fetal sheep hypothalamus, pituitary gland and adrenal

Journal of Molecular Endocrinology

Yang, K. and Hammond, G.L. and Challis, J.R.G.

DOI: 10.1677/jme.0.0080173

Novel Testicular Products of the Human SHBG/ABP Gene

Follicle Stimulating Hormone

Geoffrey L. Hammond

DOI: 10.1007/978-1-4684-7103-8_21

A Leu His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol

Journal of Steroid Biochemistry and Molecular Biology

Smith, C.L. and Power, S.G.A. and Hammond, G.L.

DOI: 10.1016/0960-0760(92)90107-T

Selective removal of glycosylation sites from sex hormone-binding globulin by site-directed mutagenesis

Endocrinology

Bocchinfuso1, W.P. and Ma, K.-L. and Lee, W.M. and Rodenhiser, S.W. and Hammond, G.L.

DOI: 10.1210/endo.131.5.1425432

Levels of surfactant-associated protein messenger ribonucleic acids in rabbit lung during perinatal development and after hormonal treatment

Endocrinology

Connelly, I.H. and Hammond, G.L. and Harding, P.G.R. and Possmayer, F.

DOI: 10.1210/endo-129-5-2583

Effect of adrenocorticotropin administration on the biosynthesis of corticosteroid-binding globulin in fetal sheep

Endocrinology

Jacobs, R.A. and Han, V.K.M. and Hammond, G.L. and Challis, J.R.G.

DOI: 10.1210/endo-128-4-1960

Ontogeny of corticosteroid-binding globulin biosynthesis in the rat

Endocrinology

Smith, C.L. and Hammond, G.L.

DOI: 10.1210/endo-128-2-983

An amino acid substitution in biobreeding rat corticosteroid binding globulin results in reduced steroid binding affinity

Journal of Biological Chemistry

Smith, C.L. and Hammond, G.L.

Pro-opiomelanocortin messenger RNA levels increase in the fetal sheep pituitary during late gestation

Journal of Endocrinology

Yang, K. and Challis, J.R.G. and Han, V.K.M. and Hammond, G.L.

DOI: 10.1677/joe.0.1310483

Expression and differential glycosylation of human sex hormone-binding globulin by mammalian cell lines

Molecular Endocrinology

Bocchinfuso, W.P. and Warmels-Rodenhiser, S. and Hammond, G.L.

DOI: 10.1210/mend-5-11-1723

Molecular studies of corticosteroid binding globulin structure, biosynthesis and function

Journal of Steroid Biochemistry and Molecular Biology

Hammond, G.L. and Smith, C.L. and Underhill, D.A.

DOI: 10.1016/0960-0760(91)90300-T

Interaction between corticosteroid binding globulin and activated leukocytes in vitro

Biochemical and Biophysical Research Communications

Hammond, G.L. and Smith, C.L. and Underhill, C.M. and Nguyen, V.T.T.

DOI: 10.1016/S0006-291X(05)80189-5

The human corticosteroid binding globulin gene is located on chromosome 14q31"q32.1 near two other serine protease inhibitor genes

Human Genetics

Seralini, G.-E. and Brub, D. and Gagn, R. and Hammond, G.L.

DOI: 10.1007/BF00205177

Studies on steroid binding proteins in normal tissues and tumor cell lines

Revista Espanola de Fisiologia

Reventos, J. and Hammond, G.L. and Musto, N.A. and Bardin, C.W.

Localization of the human sex hormone-binding globulin gene (SHBG) to the short arm of chromosome 17 (17p12p13)

Cytogenetic and Genome Research

Brub, D. and Sralini, G.E. and Gagn, R. and Hammond, G.L.

DOI: 10.1159/000132958

Rabbit corticosteroid-binding globulin: Primary structure and biosynthesis during pregnancy

Molecular Endocrinology

Seralini, G.-E. and Smith, C.L. and Hammond, G.L.

DOI: 10.1210/mend-4-8-1166

Expression of mature pulmonary surfactant-associated protein B (SP-B) in Escherichia coli using truncated human SP-B cDNAs

Biochemistry and Cell Biology

Yao, L.-J. and Richardson, C. and Ford, C. and Mathialagan, N. and Mackie, G. and Hammond, G.L. and Harding, P.G.R. and Possmayer, F.

DOI: 10.1139/o90-080

Molecular properties of corticosteroid binding globulin and the sex-steroid binding proteins

Endocrine Reviews

Hammond, G.L.

DOI: 10.1210/edrv-11-1-65

A role for corticosteroid-binding globulin in delivery of cortisol to activated neutrophils

Journal of Clinical Endocrinology and Metabolism

Hammond, G.L. and Smith, C.L. and Paterson, N.A.M. and Sibbald, W.J.

DOI: 10.1210/jcem-71-1-34

The human sex hormone-binding globulin gene contains exons for androgen-binding protein and two other testicular messenger RNAs

Molecular Endocrinology

Hammond, G.L. and Underhill, D.A. and Rykse, H.M. and Smith, C.L.

DOI: 10.1210/mend-3-11-1869

Organization of the human corticosteroid binding globulin geneand analysis of its 5-flankingregion

Molecular Endocrinology

Underhill, D.A. and Hammond, G.L.

DOI: 10.1210/mend-3-9-1448

Identification of proteins immunochemically related to human pregnancy-specific 1-glycoprotein in the rat placenta

Endocrinology

Ogilvie, S. and Kvello-Stenstrom, A.G. and Hammond, G. and Shiverick, K.T. and Buhi, W.C. and Larkin, L.H.

DOI: 10.1210/endo-125-1-287

Isolation and characterization of the cDNA for pulmonary surfactant-associated protein-B (SP-B) in the rabbit

Biochemical and Biophysical Research Communications

Xu, J. and Richardson, C. and Ford, C. and Spencer, T. and Li-juan, Y. and Mackie, G. and Hammond, G. and Possmayer, F.

DOI: 10.1016/0006-291X(89)91659-8

Rat corticosteroid binding globulin: Primary structure and messenger ribonucleic acid levels in the liver under different physiological conditions

Molecular Endocrinology

Smith, C.L. and Hammond, G.L.

DOI: 10.1210/mend-3-2-420

Biological half-life and transfer of maternal corticosteroid-binding globulin to amniotic fluid in the rabbit

Endocrinology

Seralini, G.-E. and Underhill, C.M. and Smith, C.L. and Nguyen, V.T.T. and Hammond, G.L.

DOI: 10.1210/endo-125-3-1321

Hormonal regulation of rat Androgen-Binding Protein (ABP) messenger ribonucleic acid and homology of human testosterone-estradiol-binding globulin and abp complementary deoxyribonucleic acids

Molecular Endocrinology

Reventos, J. and Hammond, G.L. and Crozat, A. and Brooks, D.E. and Gunsalus, G.L. and Bardin, C.W. and Musto, N.A.

DOI: 10.1210/mend-2-2-125

Time-resolved immunofluorometric assay of sex-hormone binding globulin

Clinical Chemistry

Niemi, S. and Maentausta, O. and Bolton, N.J. and Hammond, G.L.

Molecular Analyses of Human Corticosteroid-Binding Globulin: Expression and Gene Structurea

Annals of the New York Academy of Sciences

HAMMOND, G.L.

DOI: 10.1111/j.1749-6632.1988.tb48845.x

The amino acid sequence of rat CBG deduced from a cDNA, and identification of CBG mRNA in the liver under different physiological states

Steroids

Smith, C.L. and Hammond, G.L.

DOI: 10.1016/0039-128X(88)90132-8

Isolation and characterization of the structural region of the human CBG gene

Steroids

Underhill, D.A. and Hammond, G.L.

DOI: 10.1016/0039-128X(88)90131-6

Corticosteroid binding globulin, testosterone-estradiol binding globulin, and androgen binding protein belong to protein families distinct from steroid receptors

Journal of Steroid Biochemistry

Bardin, C.W. and Gunsalus, G.L. and Musto, N.A. and Cheng, C.Y. and Reventos, J. and Smith, C. and Underhill, D.A. and Hammond, G.

DOI: 10.1016/0022-4731(88)90085-4

Time-resolved immunofluorometric assay of human SHBG

Steroids

Niemi, S. and Mentausta, O. and Bolton, N.J. and Hammond, G.L.

DOI: 10.1016/0039-128X(88)90173-0

Primary structure of human corticosteroid binding globulin, deduced from hepatic and pulmonary cDNAs, exhibits homology with serine protease inhibitors

Proceedings of the National Academy of Sciences of the United States of America

Hammond, G.L. and Smith, C.L. and Goping, I.S. and Underhill, D.A. and Harley, M.J. and Reventos, J. and Musto, N.A. and Gunsalus, G.L. and Bardin, C.W.

DOI: 10.1073/pnas.84.15.5153

The cDNA-deduced primary structure of human sex hormone-binding globulin and location of its steroid-binding domain

FEBS Letters

Hammond, G.L. and Underhill, D.A. and Smith, C.L. and Goping, I.S. and Harley, M.J. and Musto, N.A. and Cheng, C.Y. and Bardin, C.W.

DOI: 10.1016/0014-5793(87)80121-7

Plasma levels of cortisol and corticosteroid binding globulin during use of norplantr -2 implants

Contraception

Olsson, S.-E. and Odlind, V. and Hammond, G.

DOI: 10.1016/0010-7824(87)90072-2

Isolation and Characterization of cDNA Probes for Human CBG and Rat ABP

Gene Regulation by Steroid Hormones III

G. L. Hammond and J. Reventos and N. A. Musto and G. L. Gunsalus and C. W. Bardin

DOI: 10.1007/978-1-4612-4686-2_10

Identification and measurement of sex hormone binding globulin1 (SHBG) and corticosteroid binding globulin2 (CBG) in human saliva

European Journal of Endocrinology

G. L. Hammond and M. S. Langley

DOI: 10.1530/acta.0.1120603

08 / 1986

Physicochemical characteristics of human sex hormone binding globulin: Evidence for two identical subunits

Journal of Steroid Biochemistry

Hammond, G.L. and Robinson, P.A. and Sugino, H. and Ward, D.N. and Finne, J.

DOI: 10.1016/0022-4731(86)90442-5

Identification and measurment of sex hormone binding globulin (SHBG) and corticosteroid binding globulin (CBG) in human saliva

Acta Endocrinologica

Hammond, G.L. and Langley, M.S.

Sex hormone-binding globulin - still many questions

Scandinavian Journal of Clinical and Laboratory Investigation

Lindstedt, G. and Lundberg, P.-A. and Hammond, G.L. and Vihko, R.

DOI: 10.3109/00365518509160964

Serum steroid binding proteins and the bioavailability of estradiol in relation to breast diseases1, 2

Journal of the National Cancer Institute

Langley, M.S. and Hammond, G.L. and Anderson, D.C. and Alan, B. and Sellwood, R.A.

DOI: 10.1093/jnci/75.5.823

Identification and characterization of a human corticosteroid binding globulin variant with a reduced affinity for cortisol

Journal of Endocrinology

Robinson, P.A. and Hammond, G.L.

DOI: 10.1677/joe.0.1040269

A phylogenetic study of the structural and functional characteristics of corticosteroid binding globulin in primates

Journal of Endocrinology

Robinson, P.A. and Hawkey, C. and Hammond, G.L.

DOI: 10.1677/joe.0.1040251

A solid-phase radioimmunoassay for human corticosteroid binding globulin

Journal of Endocrinology

Robinson, P.A. and Langley, M.S. and Hammond, G.L.

DOI: 10.1677/joe.0.1040259

A liquid-phase immunoradiometric assay (IRMA) for human sex hormone binding globulin (SHBG)

Journal of Steroid Biochemistry

Hammond, G.L. and Langley, M.S. and Robinson, P.A.

DOI: 10.1016/0022-4731(85)90192-X

Serum steroid binding protein concentrations, distribution of progestogens, and bioavailability of testosterone during treatment with contraceptives containing desogestrel or levonorgestrel

Fertility and Sterility

Geoffrey L. Hammond and Mark S. Langley and Philip A. Robinson and Simo Nummi and Leif Lund

DOI: 10.1016/s0015-0282(16)47956-2

07 / 1984

Characterization of a monoclonal antibody to human sex hormone binding globulin

FEBS Letters

Hammond, G.L. and Robinson, P.A.

DOI: 10.1016/0014-5793(84)80268-9

Serum sex hormone-binding globulin during puberty in girls and in different types of adolescent menstrual cycles

Acta Endocrinologica

Apter, D. and Bolton, N.J. and Hammond, G.L. and Vihko, R.

A versatile method for the determination of serum cortisol binding globulin and sex hormone binding globulin binding capacities

Clinica Chimica Acta

Geoffrey L. Hammond and Pertti L.A. Lhteenmki

DOI: 10.1016/0009-8981(83)90237-1

07 / 1983

Measurement of sex hormone binding globulin in human amniotic fluid: its relationship to protein and testosterone concentrations, and fetal sex

Clinical Endocrinology

G. L. HAMMOND and P. LEINONEN and N. J. BOLTON and R. VIHKO

DOI: 10.1111/j.1365-2265.1983.tb00582.x

04 / 1983

Progesterone, androstenedione, testosterone, 5a-dihydrotestosterone and androsterone concentrations in specific regions of the human brain

Journal of Steroid Biochemistry

G.L. Hammond and J. Hirvonen and R. Vihko

DOI: 10.1016/0022-4731(83)90086-9

02 / 1983

Serum non-protein bound percentage and distribution of the progestin ST-1435: No effect of ST-1435 treatment on plasma SHBG and CBG binding capacities

Acta Endocrinologica

Lahteenmaki, P.L.A. and Hammond, G.L. and Luukkainen, T.

DOI: 10.1530/acta.0.1020307

Distribution and percentages of non-protein bound contraceptive steroids in human serum

Journal of Steroid Biochemistry

Geoffrey L. Hammond and Pertti L.A. Lhteenmki and Pekka Lhteenmki and Tapani Luukkainen

DOI: 10.1016/0022-4731(82)90629-x

10 / 1982

Serum concentrations of total and non-protein-bound oestradiol in patients with breast cancer and in normal controls

International Journal of Cancer

J. W. Moore and G. M. G. Clark and R. D. Bulbrook and J. L. Hayward and J. T. Murai and G. L. Hammond and P. K. Siiteri

DOI: 10.1002/ijc.2910290105

01 / 1982

The Serum Transport of Steroid Hormones

Proceedings of the 1981 Laurentian Hormone Conference

PENTTI K. SIITERI and JAMES T. MURAI and WILLIAM J. RAYMOURE and ROBERT W. KUHN and GEOFFREY L. HAMMOND and JEFFREY A. NISKER

DOI: 10.1016/b978-0-12-571138-8.50016-0

Versatile semi-automated sample processor and gamma counter to increase radioimmunoassay efficiency

Clinical Chemistry

Vihko, R. and Bolton, N. and Hammond, G.L.

DOI: 10.1093/clinchem/28.4.699

Free estradiol in postmenopausal women with and without endometrial cancer,Freies stradiol bei frauen nach der menopause mit bzw. ohne endometriumkarzinom

Gynakologisch-geburtshilfliche Rundschau

Davidson, B.J. and Gambone, J.C. and Lagasse, L.D. and Castaldo, T.W. and Hammond, G.L. and Siiteri, P.K. and Judd, H.L.

DOI: 10.1159/000269292

Distribution and concentrations of androgens in epithelial and stromal compartments of the human benign hypertrophic prostate

Journal of Endocrinology

N. J. BOLTON and R. LAHTONEN and G. L. HAMMOND and R. VIHKO

DOI: 10.1677/joe.0.0900125

07 / 1981

Free Estradiol in Postmenopausal Women with and without Endometrial Cancer

The Journal of Clinical Endocrinology & Metabolism

B. J. DAVIDSON and J. C GAMBONE and L. D. LAGASSE and T. W. CASTALDO and G. L. HAMMOND and P. K. SIITERI and H. L. JUDD

DOI: 10.1210/jcem-52-3-404

03 / 1981

Long-Term Effects of Endocrine Treatment on Serum Pituitary Hormones in Advanced Prostatic Carcinoma Patients

Scandinavian Journal of Urology and Nephrology

O. Lukkarinen and G. L. Hammond and M. Kontturi and R. Vihko

DOI: 10.3109/00365598109179604

01 / 1981

Gynecomastia and high serum testosterone in a 10 year old boy,Gynekomastia ja korkea seerumin testosteroniarvo murrosikiseli pojalla.

Duodecim

Viinikka, L. and Hammond, G.L. and Hortling, H. and Leinonen, P. and Vihko, R.

The clinical and endocrine evaluation of a pubertal boy with incomplete male pseudohermaphroditism type 1

Annals of Clinical Research

Viinikka, L. and Hammond, G.L. and Hortling, H. and Leinonen, P. and Vihko, R.

Serum non-protein bound percentages and distribution of contraceptive steroids

Journal of Steroid Biochemistry

Hammond, G.L. and Lahteenmaki, P. and Lahteenmaki, P. and Luukkainen, T.

Serum sex hormone-binding globulin capacity and the percentage of free estradiol in postmenopausal women with and without endometrial carcinoma

American Journal of Obstetrics and Gynecology

J.A. Nisker and G.L. Hammond and B.J. Davidson and A.M. Frumar and N.K. Takaki and H.L. Judd and P.K. Siiteri

DOI: 10.1016/0002-9378(80)90080-0

11 / 1980

Peripheral and prostatic vein steroid concentrations in benign prostatic hypertrophy patients before and after removal of the adenoma

Scandinavian Journal of Urology and Nephrology

Lukkarinen, O. and Hammond, G.L. and Kontturi, M. and Vihko, R.

DOI: 10.3109/00365598009179566

More on Fatness and Reproduction

New England Journal of Medicine

Nisker, J.A. and Hammond, G.L. and Siiteri, P.K. and Frisch, R.E. and Fishman, J.

DOI: 10.1056/NEJM198011063031919

Testosterone and some of its precursors and metabolites in the human epididymis

Journal of Clinical Endocrinology and Metabolism

Leinonen, P. and Hammond, G.L. and Vihko, R.

DOI: 10.1210/jcem-51-3-423

Long-term effects of endocrine treatment on serum steroids in advanced prostatic carcinoma patients

Investigative Urology

Lukkarinen, O. and Hammond, G.L. and Kontturi, M. and Vihko, R.

Effect of oestrogen treatment on testicular LH/HCG receptors and endogenous steroids in prostatic cancer patients

Clinical Endocrinology

I. HUHTANIEMI and P. LEINONEN and G. L. HAMMOND and R. VIHKO

DOI: 10.1111/j.1365-2265.1980.tb03424.x

Estimation of the percentage of free steroid in undiluted serum by centrifugal ultrafiltration-dialysis

Journal of Biological Chemistry

Hammond, G.L. and Nisker, J.A. and Jones, L.A. and Siiteri, P.K.

SERUM PREGNENOLONE, PROGESTERONE, 17a-HYDROXYPROGESTERONE, ANDROSTENEDIONE, TESTOSTERONE, 5a-DIHYDROTESTOSTERONE AND ANDROSTERONE DURING PUBERTY IN BOYS

Clinical Endocrinology

A. PAKARINEN and G. L. HAMMOND and R. VIHKO

DOI: 10.1111/j.1365-2265.1979.tb03098.x

11 / 1979

Adrenocortical function in puberty serum ACTH, cortisol and dehydroepiandrosterone in girls and boys

Acta Paediatrica

D. APTER and A. PAKARINEN and G. L. HAMMOND and R. VIHKO

DOI: 10.1111/j.1651-2227.1979.tb05062.x

09 / 1979

Automation of steroid radioimmunoassays for clinical and research purposes

Journal of Steroid Biochemistry

R. Vihko and G.L. Hammond

DOI: 10.1016/0022-4731(79)90286-3

07 / 1979

The hormonal status of patients with benign prostatic hypertrophy: FSH, LH, TSH and prolactin responses to releasing hormones

Clinical Endocrinology

G. L. HAMMOND and O. LUKKARINEN and P. VIHKO and M. KONTTURI and R. VIHKO

DOI: 10.1111/j.1365-2265.1979.tb02113.x

06 / 1979

Serum steroids and pituitary hormones in infants with particular reference to testicular activity

Journal of Clinical Endocrinology and Metabolism

Hammond, G.L. and Koivisto, M. and Kouvalainen, K. and Vihko, R.

DOI: 10.1210/jcem-49-1-40

Discrete modular system for automation of radioimmunoassay of serum choriomammotropin

Clinical Chemistry

Hammond, G.L. and Leinonen, P. and Vihko, R.

DOI: 10.1093/clinchem/25.1.129

The concentration of six steroids in human testis after polyestradiolphosphate (Estradurin) treatment of prostatic carcinoma

Acta Endocrinologica, Supplement

Leinonen, P. and Hammond, G.L. and Vihko, R.

A method for identification and follow-up of patients with a steroid-21-hydroxylase deficiency

Clinica Chimica Acta

S{\"o}lyom, J. and Hammond, G.L. and Vihko, R.

DOI: 10.1016/0009-8981(79)90104-9

Testicular steroid secretion and peripheral serum steroid concentrations in patients with prostatic carcinoma after short-term estrogen treatment

Investigative Urology

Lukkarinen, O. and Hammond, G.L. and Kontturi, M. and Vihko, R.

Serum sex hormone binding globulin and testosterone binding after estradiol administration, castration, and their combination in men with prostatic carcinoma

Investigative Urology

Leinonen, P. and Hammond, G.L. and Lukkarinen, O. and Vihko, R.

Serum steroids in normal males and patients with prostatic diseases

Clinical Endocrinology

G. L. HAMMOND and M. KONTTURI and P. VIHKO and R. VIHKO

DOI: 10.1111/j.1365-2265.1978.tb02189.x

08 / 1978

Endogenous steroid levels in the human prostate from birth to old age: a comparison of normal and diseased tissues

Journal of Endocrinology

G. L. HAMMOND

DOI: 10.1677/joe.0.0780007

07 / 1978

The Radioimmunoassay of Testosterone, 5a-Dihydrotestosterone and Their Precursors in the Human Testis

International Journal of Andrology

G. L. Hammond and V. Ahonen and R. Vihko

DOI: 10.1111/j.1365-2605.1978.tb00031.x

06 / 1978

The Simultaneous Radioimmunoassay of Seven Steroids in Human Spermatic and Peripheral Venous Blood

The Journal of Clinical Endocrinology & Metabolism

G. L. HAMMOND and A. RUOKONEN and M. KONTTURI and E. KOSKELA and R. VIHKO

DOI: 10.1210/jcem-45-1-16

07 / 1977

Spermatic vein steroids,PROC. V. INT. CONGR. ENDOCRINOLOGY, VOL. I

EXCERPTA MEDICA, AMSTERDAM, ICS

Vihko, R. and Hammond, G.

Endogenous levels of eight steroids in the human prostate from birth to old age [proceedings]

Journal of Endocrinology

Hammond, G.L.

Automation of radioimmunoassays for some sex steroids with use of both iodinated and tritiated ligands

Clinical Chemistry

Hammond, G.L. and Viinikka, L. and Vihko, R.

DOI: 10.1093/clinchem/23.7.1250

SERUM FSH, LH AND PROLACTIN IN NORMAL MALES AND PATIENTS WITH PROSTATIC DISEASES

Clinical Endocrinology

HAMMOND, G.L. and KONTTURI, M. and M{\"A}{\"A}TT{\"A}L{\"A}, P. and PUUKKA, M. and VIHKO, R.

DOI: 10.1111/j.1365-2265.1977.tb01304.x

Metal"androgen interrelationships in carcinoma and hyperplasia of the human prostate

Journal of Endocrinology

F. K. HABIB and G. L. HAMMOND and I. R. LEE and J. B. DAWSON and M. K. MASON and P. H. SMITH and S. R. STITCH

DOI: 10.1677/joe.0.0710133

10 / 1976

Proceedings: Testosterone, dihydrotestosterone, zinc and cadmium in prostatic tissue.

Journal of Endocrinology

Habib, F.K. and Hammond, G.L. and Stitch, S.R. and Dawson, J.B.

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