Publications

Real-World Effectiveness of Common Treatment Strategies for Juvenile Idiopathic Arthritis: Results From a Canadian Cohort
Arthritis Care and Research
Chhabra, A. and Oen, K. and Huber, A.M. and Shiff, N.J. and Boire, G. and Benseler, S.M. and Berard, R.A. and Scuccimarri, R. and Feldman, B.M. and Lim, L.S.H. and Barsalou, J. and Bruns, A. and Cabral, D.A. and Ch{\'e}deville, G. and Ellsworth, J. and Houghton, K. and Lang, B. and Morishita, K. and Rumsey, D.G. and Rosenberg, A.M. and Tse, S.M. and Watanabe Duffy, K. and Duffy, C.M. and Guzman, J. and Bolaria, R. and Gross, K. and Turvey, S.E. and Chan, M. and Tucker, L.B. and Petty, R. and Johnson, N. and Luca, N. and Miettunen, P. and Schmeling, H. and Gerhold, K. and Larch{\'e}, M. and Levy, D.M. and Laxer, R.M. and Feldman, D. and Spiegel, L. and Schneider, R. and Silverman, E. and Cameron, B. and Yeung, R.S.M. and Roth, J. and Jurencak, R. and Gibbon, M. and Chetaille, A.-L. and Dorval, J. and Campillo, S. and LeBlanc, C. and Ch{\'e}deville, G. and Haddad, E. and Cyr, C.S. and Ramsey, S.E. and Stringer, E. and Dancey, P.
DOI: 10.1002/acr.23922
2020

Associations of clinical and inflammatory biomarker clusters with juvenile idiopathic arthritis categories
Rheumatology (United Kingdom)
Rezaei, E. and Hogan, D. and Trost, B. and Kusalik, A.J. and Boire, G. and Cabral, D.A. and Campillo, S. and Ch{\'e}deville, G. and Chetaille, A.-L. and Dancey, P. and Duffy, C. and Duffy, K.W. and Eng, S.W.M. and Gordon, J. and Guzman, J. and Houghton, K. and Huber, A.M. and Jurencak, R. and Lang, B. and Laxer, R.M. and Morishita, K. and Oen, K.G. and Petty, R.E. and Ramsey, S.E. and Scherer, S.W. and Scuccimarri, R. and Spiegel, L. and Stringer, E. and Taylor-Gjevre, R.M. and Tse, S.M.L. and Tucker, L.B. and Turvey, S.E. and Tupper, S. and Wintle, R.F. and Yeung, R.S.M. and Rosenberg, A.M.
DOI: 10.1093/rheumatology/kez382
2020

The Accuracy of Prevalent Vertebral Fracture Detection in Children Using Targeted Case-Finding Approaches
Journal of Bone and Mineral Research
Ma, J. and Siminoski, K. and Wang, P. and Alos, N. and Cummings, E.A. and Feber, J. and Halton, J. and Ho, J. and Houghton, K. and Lang, B. and Miettunen, P.M. and Scuccimarri, R. and Jaremko, J.L. and Koujok, K. and Lentle, B. and Matzinger, M.A. and Shenouda, N. and Rauch, F. and Ward, L.M.
DOI: 10.1002/jbmr.3922
2020

Worse Quality of Life, Function, and Pain in Children With Enthesitis, Irrespective of Their Juvenile Arthritis Category
Arthritis Care and Research
Rumsey, D.G. and Guzman, J. and Rosenberg, A.M. and Huber, A.M. and Scuccimarri, R. and Shiff, N.J. and Bruns, A. and Feldman, B.M. and Eurich, D.T. and Benseler, S. and Berard, R. and Boire, G. and Bolaria, R. and Cabral, D. and Cameron, B. and Campillo, S. and Chan, M. and Ch{\'e}deville, G. and Chetaille, A.-L. and Dancey, P. and Dorval, J. and Duffy, C. and Ellsworth, J. and Feldman, D. and Gross, K. and Haddad, E. and Houghton, K. and Johnson, N. and Jurencak, R. and Lang, B. and Larch{\'e}, M. and Laxer, R. and LeBlanc, C. and Levy, D. and Luca, N. and Miettunen, P. and Morishita, K. and Oen, K. and Petty, R. and Ramsey, S. and Roth, J. and Saint-Cyr, C. and Schmeling, H. and Schneider, R. and Silverman, E. and Spiegel, L. and Stringer, E. and Tse, S. and Tucker, L. and Turvey, S. and Watanabe Duffy, K. and Yeung, R.
DOI: 10.1002/acr.23844
2020

Predicting which children with juvenile idiopathic arthritis will not attain early remission with conventional treatment: Results from the Reacch-out cohort
Journal of Rheumatology
Guzman, J. and Henrey, A. and Loughin, T. and Berard, R.A. and Shiff, N.J. and Jurencak, R. and Huber, A.M. and Oen, K. and Gerhold, K. and Feldman, B.M. and Scuccimarri, R. and Houghton, K. and Ch{\'e}deville, G. and Morishita, K. and Lang, B. and Dancey, P. and Rosenberg, A.M. and Barsalou, J. and Bruns, A. and Duffy, K.W. and Benseler, S. and Duffy, C.M. and Tucker, L.B. and Bolaria, R. and Gross, K. and Turvey, S.E. and Cabral, D. and Petty, R. and Ellsworth, J. and Johnson, N. and Miettunen, P. and Schmeling, H. and Larch{\'e}, M. and Levy, D.M. and Laxer, R.M. and Feldman, D. and Spiegel, L. and Schneider, R. and Tse, S.M.L. and Silverman, E. and Cameron, B. and Yeung, R.S.M. and Roth, J. and Gibbon, M. and Chetaille, A.-L. and Dorval, J. and Boire, G. and Campillo, S. and LeBlanc, C. and Haddad, E. and Cyr, C.St. and Ramsey, S.E. and Stringer, E.
DOI: 10.3899/jrheum.180456
2019

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus
Arthritis Care and Research
Brunner, H.I. and Holland, M.J. and Beresford, M.W. and Ardoin, S.P. and Appenzeller, S. and Silva, C.A. and Flores, F. and Goilav, B. and Avar Aydin, P.O. and Wenderfer, S.E. and Levy, D.M. and Ravelli, A. and Khubchandani, R. and Avcin, T. and Klein-Gitelman, M.S. and Ruperto, N. and Feldman, B.M. and Ying, J. and Battagliotti, C. and Brusco, M.I. and Cuttica, R. and De Cunto, C. and Espada, G. and Farfan, M. and Garay, S. and Marcantoni, M. and Marcela, A. and Meiorin, S. and Rama, M.E. and Russo, R. and Torre Walsh, C. and Zamparo, C. and Adib, N. and Akikusa, J. and Boros, C. and Lee, S.J. and Mckay, D. and Piper, S. and Joos, R. and Bica, B. and Campos, L. and Cavalcanti, A. and do Prado, R. and Donner-Maliki, A. and Fernandes, T. and Fonseca, A. and Gasparello de Almeida, R. and Guariento, A. and Gusman, C. and Jusan Fiorot, F. and Knupp Oliveira, S. and Len, C. and Arruda Campos, L.M. and Machado, S. and Marques, L. and Martins de Carvalho, L. and Moulin, R. and Pedroso, S. and Pileggi, G. and Romanelli, P.R.S. and Saad-Magalhaes, C. and Sakamoto, A. and Santos, M.C. and Silva, M.F. and Spelling, P. and Sztajnbok, S. and Terreri, M. and Cabral, D. and Ch{\'e}deville, G. and Ellsworth, J. and Huber, A. and Tucker, L. and Houghton, K. and Borzutzky, A. and Ladino, M. and Norambuena, X. and Eraso, R. and Mosquera, A. and Velasquez, M. and Harjacek, M. and Jelusic, M. and Coto Hermosilla, C. and Dolezalova, P. and Nielsen, S. and Tineo, C. and Alegria, M. and Dressler, F. and Foell, D. and Ganser, G. and Hinze, C. and Hufnagel, M. and Lutz, T. and Trauzeddel, R. and Boiu, S. and Trachana, M. and Tsitsami, E. and Cifuentes, M. and Orb{\'a}n, I. and Aggarwal, A. and Sawhney, S. and Butbul Aviel, Y. and Cimaz, R. and Maggio, M.C. and Rumba-Rozenfelde, I. and Hashad, S. and Lim, S.C. and Abud, C. and Burgos-Vargas, R. and Carre{\~n}o-Manjarrez, R. and Enciso Pelaez, S. and Hernandez-Huirache, H. and Maldonado Vel{\'a}zquez, R. and Orozco, J. and Rodriguez-Lozano, A.L. and Rojas Pacheco, O.E. and Su{\'a}rez Larios, L.M. and Vega, G. and Ram{\'i}rez Miramontes, J.V. and Ru{\'i}z Lopez, I.K. and Kamphuis, S. and Schonenberg-Meinema, D. and Concannon, A. and Yan, J. and Jarquin Jaime, M. and Al Abrawi, S. and Vega, C. and Lopez-Benitez, J. and Ib{\'a}{\~n}ez Estrella, A. and Miraval, T. and Dans, L. and Kimseng, K.J. and Opoka-Winiarska, V. and Rutkowska-Sak, L. and Smolewska, E. and Conde, M. and Guedes, M. and del Valle, E. and Quintero-Del Rio, A. and Ailioaie, C. and Sparchez, M. and Alekseeva, E. and Keltsev, V. and Al-Mayouf, S. and Asiri, A. and Suwairi, W. and Susic, G. and Vijatov-Djuric, G. and Ang, E. and Arkachaisri, T. and Boteanu, A.-L. and Lopez-Robledillo, J.C. and Medrano San Ildefonso, M. and Modesto, C. and Calvo, I. and Sotoca-Fernandez, J. and Bolt, I. and Vilaiyuk, S. and Al-Abadi, E. and Baildam, E. and Fotis, L. and Pain, C. and Pilkington, C. and Abulaban, K. and Barbar-Smiley, F. and Binstadt, B. and Bohnsack, J. and Boneparth, A. and Brown, D. and Chira, P. and Cron, R. and Dedeoglu, F. and Eberhard, A. and Gedalia, A. and Grom, A. and Henrickson, M. and Hom, C. and Huggins, J. and Jerath, R. and Jones, J. and Jung, L. and Kingsbury, D. and Lai, J. and Lovell, D. and Nanda, K. and Nocton, J. and Olson, J. and O?Neil, K. and Onel, K. and Punaro, L. and Reiff, A. and Rouster-Stevens, K. and Ruth, N. and Schikler, K. and Murphy Schmidt, K. and Schulert, G. and Shaham, B. and Singer, N. and Smith, J. and Sundel, R. and Syverson, G. and Vega-Fernandez, P. and Vehe, R. and Wagner-Weiner, L. and Cameto, J. and Jurado, R. and Maldonado, I.
DOI: 10.1002/acr.23834
2019

Complexity in unclassified auto-inflammatory disease: A case report illustrating the potential for disease arising from the allelic burden of multiple variants
Pediatric Rheumatology
Tucker, L.B. and Lamot, L. and Niemietz, I. and Chung, B.K. and Cabral, D.A. and Houghton, K. and Petty, R.E. and Morishita, K.A. and Rice, G.I. and Turvey, S.E. and Gibson, W.T. and Brown, K.L.
DOI: 10.1186/s12969-019-0374-x
2019

Feasibility and safety of a 6-month exercise program to increase bone and muscle strength in children with juvenile idiopathic arthritis
Pediatric Rheumatology
DOI: 10.1186/s12969-018-0283-4
12/2018

“I just want to get better”: experiences of children and youth with juvenile idiopathic arthritis in a home-based exercise intervention
Pediatric Rheumatology
DOI: 10.1186/s12969-018-0273-6
12/2018

Does competitive swimming affect lung growth?
Physiological Reports
DOI: 10.14814/phy2.13816
08/2018

Trajectories of pain severity in juvenile idiopathic arthritis
PAIN
Natalie J. Shiff and Susan Tupper and Kiem Oen and Jaime Guzman and Hyun Lim and Chel Hee Lee and Rhonda Bryce and Adam M. Huber and Gilles Boire and Paul Dancey and Brian Feldman and Ronald Laxer and Paivi Miettunen and Heinrike Schmeling and Karen Watanabe Duffy and Deborah M. Levy and Stuart Turvey and Roxana Bolaria and Alessandra Bruns and David A. Cabral and Sarah Campillo and Gaëlle Chédeville and Debbie Ehrmann Feldman and Elie Haddad and Kristin Houghton and Nicole Johnson and Roman Jurencak and Bianca Lang and Maggie Larche and Kimberly Morishita and Suzanne Ramsey and Johannes Roth and Rayfel Schneider and Rosie Scuccimarri and Lynn Spiegel and Elizabeth Stringer and Shirley M. Tse and Rae Yeung and Ciarán M. Duffy and Lori B. Tucker
DOI: 10.1097/j.pain.0000000000001064
01/2018

Health-Related Quality of Life in an Inception Cohort of Children With Juvenile Idiopathic Arthritis: A Longitudinal Analysis
Arthritis Care and Research
Oen, K. and Guzman, J. and Dufault, B. and Tucker, L.B. and Shiff, N.J. and Duffy, K.W. and Lee, J.J.Y. and Feldman, B.M. and Berard, R.A. and Dancey, P. and Huber, A.M. and Scuccimarri, R. and Cabral, D.A. and Morishita, K.A. and Ramsey, S.E. and Rosenberg, A.M. and Boire, G. and Benseler, S.M. and Lang, B. and Houghton, K. and Miettunen, P.M. and Ch{\'e}deville, G. and Levy, D.M. and Bruns, A. and Schmeling, H. and Haddad, E. and Yeung, R.S.M. and Duffy, C.M.
DOI: 10.1002/acr.23236
2018

Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort
Pediatric Rheumatology
Jaime Guzman and Tristan Kerr and Leanne M. Ward and Jinhui Ma and Kiem Oen and Alan M. Rosenberg and Brian M. Feldman and Gilles Boire and Kristin Houghton and Paul Dancey and Rosie Scuccimarri and Alessandra Bruns and Adam M. Huber and Karen Watanabe Duffy and Natalie J. Shiff and Roberta A. Berard and Deborah M. Levy and Elizabeth Stringer and Kimberly Morishita and Nicole Johnson and David A. Cabral and Maggie Larché and Ross E. Petty and Ronald M. Laxer and Earl Silverman and Paivi Miettunen and Anne-Laure Chetaille and Elie Haddad and Lynn Spiegel and Stuart E. Turvey and Heinrike Schmeling and Bianca Lang and Janet Ellsworth and Suzanne E. Ramsey and Johannes Roth and Sarah Campillo and Susanne Benseler and Gaëlle Chédeville and Rayfel Schneider and Shirley M. L. Tse and Roxana Bolaria and Katherine Gross and Debbie Feldman and Bonnie Cameron and Roman Jurencak and Jean Dorval and Claire LeBlanc and Claire St. Cyr and Michele Gibbon and Rae S. M. Yeung and Ciarán M. Duffy and Lo
DOI: 10.1186/s12969-017-0196-7
08/2017

Biologic therapies for refractory juvenile dermatomyositis: five years of experience of the Childhood Arthritis and Rheumatology Research Alliance in North America.
Pediatric rheumatology online journal
DOI: 10.1186/s12969-017-0174-0
PubMed: 28610606
06/2017

Does Competitive Swimming During Puberty Affect Lung Development?
Medicine & Science in Sports & Exercise
Joshua M. Bovard and Joseph F. Welch and Kristin M. Houghton and Donald C. McKenzie and James E. Potts and A. William Sheel
DOI: 10.1249/01.mss.0000516854.42976.41
05/2017

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
Clinical Immunology
Robert J. Ragotte and Anita Dhanrajani and Julian Pleydell-Pearce and Kate L. Del Bel and Maja Tarailo-Graovac and Clara van Karnebeek and Jefferson Terry and Christof Senger and Margaret L. McKinnon and Michael Seear and Julie S. Prendiville and Lori B. Tucker and Kristin Houghton and David A. Cabral and Jaime Guzman and Ross E. Petty and Kelly L. Brown and Jenny Tekano and John Wu and Kimberly A. Morishita and Stuart E. Turvey
DOI: 10.1016/j.clim.2016.12.006
02/2017

Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy
Arthritis Research & Therapy
Arndt H. Brachat and for the Pediatric Rheumatology International Trials Organization (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Alexei A. Grom and Nico Wulffraat and Hermine I. Brunner and Pierre Quartier and Riva Brik and Liza McCann and Huri Ozdogan and Lidia Rutkowska-Sak and Rayfel Schneider and Valeria Gerloni and Liora Harel and Maria Terreri and Kristin Houghton and Rik Joos and Daniel Kingsbury and Jorge M. Lopez-Benitez and Stephan Bek and Martin Schumacher and Marie-Anne Valentin and Hermann Gram and Ken Abrams and Alberto Martini and Daniel J. Lovell and Nanguneri R. Nirmala and Nicolino Ruperto
DOI: 10.1186/s13075-016-1212-x
01/2017

Management of Juvenile Idiopathic Arthritis 2015: A Position Statement from the Pediatric Committee of the Canadian Rheumatology Association
The Journal of Rheumatology
T. CELLUCCI and J. GUZMAN and R. E. PETTY and M. BATTHISH and S. M. BENSELER and J. E. ELLSWORTH and K. M. HOUGHTON and C. M. A. LeBLANC and A. M. HUBER and N. LUCA and H. SCHMELING and N. J. SHIFF and G. S. SOON and S. M. L. TSE and On behalf of the Pediatric Committee of the Canadian Rheumatology Association
DOI: 10.3899/jrheum.160074
10/2016

Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study.
Arthritis & rheumatology (Hoboken, N.J.)
DOI: 10.1002/art.39729
PubMed: 27111558
10/2016

Northern Highlights: Exercise is Medicine – Keeping Kids with Arthritis Active
Canadian Rheumatology Association Journal
10/2016

‘It might hurt, but you have to push through the pain’
Journal of Child Health Care
Douglas L Race and Joanie Sims-Gould and Lori B Tucker and Ciaran M Duffy and Debbie Ehrmann Feldman and Michele Gibbon and Kristin M Houghton and Jennifer N Stinson and Elizabeth Stringer and Shirley ML Tse and Heather A McKay
DOI: 10.1177/1367493516632616
07/2016

Gene Expression Deconvolution for Uncovering Molecular Signatures in Response to Therapy in Juvenile Idiopathic Arthritis.
PloS one
DOI: 10.1371/journal.pone.0156055
PubMed: 27244050
05/2016

Development of System-level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada
The Journal of Rheumatology
C. E. H. Barber and D. A. Marshall and D. P. Mosher and P. Akhavan and L. Tucker and K. Houghton and M. Batthish and D. M. Levy and H. Schmeling and J. Ellsworth and H. Tibollo and S. Grant and D. Khodyakov and D. Lacaille and V. Ahluwalia and H. Averns and C. Barnabe and C. Bombardier and S. J. Bartlett and S. Bernatsky and J. Burt and D. Feldman and D. D. Gladman and B. Greene and B. Haraoui and N. Haroon and C. Hofstetter and A. M. Huber and S. Keeling and B. Lang and S. A. Le Clercq and T. Lupton and R. Mandhane and K. Morishita and A. Papachristos and P. Patrick and D. Richards and D. Robinson and N. J. Shiff and T. Taylor and R. Taylor-Gjevre and G. T. D. Thomson and C. Thorne and K. Toupin-April and P. Tugwell and M. D. Westby and J. Widdifield and L. Woodhouse and M. Zummer and The Arthritis Alliance of Canada Performance Measurement Development Panel
DOI: 10.3899/jrheum.150839
01/2016

Noninflammatory Musculoskeletal Pain
Textbook of Pediatric Rheumatology
Claire LeBlanc and Kristin Houghton
DOI: 10.1016/b978-0-323-24145-8.00051-x
2016

Proposal for a candidate core set of fitness and strength tests for patients with childhood or adult idiopathic inflammatory myopathies
Journal of Rheumatology
Van Der Stap, D.K.D. and Rider, L.G. and Alexanderson, H. and Huber, A.M. and Gualano, B. and Gordon, P. and Van Der Net, J. and Mathiesen, P. and Johnson, L.G. and Ernste, F.C. and Feldman, B.M. and Houghton, K.M. and Singh-Grewal, D. and Kutzbach, A.G. and Munters, L.A. and Takken, T.
DOI: 10.3899/jrheum.150270
2016

The risk and nature of flares in juvenile idiopathic arthritis: Results from the ReACCh-Out cohort
Annals of the Rheumatic Diseases
Guzman, J. and Oen, K. and Huber, A.M. and Duffy, K.W. and Boire, G. and Shiff, N. and Berard, R.A. and Levy, D.M. and Stringer, E. and Scuccimarri, R. and Morishita, K. and Johnson, N. and Cabral, D.A. and Rosenberg, A.M. and Larch{\'e}, M. and Dancey, P. and Petty, R.E. and Laxer, R.M. and Silverman, E. and Miettunen, P. and Chetaille, A.-L. and Haddad, E. and Houghton, K. and Spiegel, L. and Turvey, S.E. and Schmeling, H. and Lang, B. and Ellsworth, J. and Ramsey, S.E. and Bruns, A. and Roth, J. and Campillo, S. and Benseler, S. and Ch{\'e}deville, G. and Schneider, R. and Tse, S.M.L. and Bolaria, R. and Gross, K. and Feldman, B. and Feldman, D. and Cameron, B. and Jurencak, R. and Dorval, J. and LeBlanc, C. and St. Cyr, C. and Gibbon, M. and Yeung, R.S.M. and Duffy, C.M. and Tucker, L.B.
DOI: 10.1136/annrheumdis-2014-207164
2016

Participation in Juvenile Idiopathic Arthritis
The Journal of Rheumatology
K. M. HOUGHTON
DOI: 10.3899/jrheum.150438
09/2015

Incident Vertebral Fractures and Risk Factors in the First Three Years Following Glucocorticoid Initiation Among Pediatric Patients With Rheumatic Disorders
Journal of Bone and Mineral Research
Claire MA LeBlanc and Jinhui Ma and Monica Taljaard and Johannes Roth and Rosie Scuccimarri and Paivi Miettunen and Bianca Lang and Adam M Huber and Kristin Houghton and Jacob L Jaremko and Josephine Ho and Nazih Shenouda and Mary Ann Matzinger and Brian Lentle and Robert Stein and Anne Marie Sbrocchi and Kiem Oen and Celia Rodd and Roman Jurencak and Elizabeth A Cummings and Robert Couch and David A Cabral and Stephanie Atkinson and Nathalie Alos and Frank Rauch and Kerry Siminoski and Leanne M Ward and the Canadian STeroid-Associated Osteoporosis in the Pediatric Population (STOPP) Consortium
DOI: 10.1002/jbmr.2511
05/2015

Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: Results from a phase 3, randomised, double-blind withdrawal trial
Annals of the Rheumatic Diseases
Brunner, H.I. and Ruperto, N. and Zuber, Z. and Keane, C. and Harari, O. and Kenwright, A. and Lu, P. and Cuttica, R. and Keltsev, V. and Xavier, R.M. and Calvo, I. and Nikishina, I. and Rubio-P{\'e}rez, N. and Alexeeva, E. and Chasnyk, V. and Horneff, G. and Opoka-Winiarska, V. and Quartier, P. and Silva, C.A. and Silverman, E. and Spindler, A. and Baildam, E. and G{\'a}mir, M.L. and Martin, A. and Rietschel, C. and Siri, D. and Smolewska, E. and Lovell, D. and Martini, A. and De Benedetti, F. and Sherrard, T. and Johnson, A. and Merritt, A. and Long, W. and Angioloni, S. and Carenini, L. and Pallotti, C. and Mosci, E. and Garrone, M. and Gregorini, I. and Scala, S. and Villa, L. and Silvestri, G. and Espada, G. and Allen, R. and Chaitow, J. and Joos, R. and Wouters, C. and Knupp, S. and Sztajnbok, F. and Cabral, D. and Houghton, K. and Roth, J. and Schmeling, H. and Job-Deslandre, C. and Jorgensen, C. and Konepaut, I. and Minden, K. and Weller, F. and Gerloni, V. and Zulian, F. and Burgos-Vargas, R. and Salazar, C.D. and Vallejo, E.S. and Calvo, A. and Chavez, J. and Zavaler, M.F. and Gruenpeter, A. and Kobusinska, K. and Sarychev, A. and Zholobova, E. and Ramanan, A. and Woo, P. and Gedalia, A. and Goodman, S. and Kimura, Y. and Onel, K. and Schikler, K.
DOI: 10.1136/annrheumdis-2014-205351
2015

The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: Results from the reacch-out cohort
Annals of the Rheumatic Diseases
Guzman, J. and Oen, K. and Tucker, L.B. and Huber, A.M. and Shiff, N. and Boire, G. and Scuccimarri, R. and Berard, R. and Tse, S.M.L. and Morishita, K. and Stringer, E. and Johnson, N. and Levy, D.M. and Duffy, K.W. and Cabral, D.A. and Rosenberg, A.M. and Larch{\'e}, M. and Dancey, P. and Petty, R.E. and Laxer, R.M. and Silverman, E. and Miettunen, P. and Chetaille, A.-L. and Haddad, E. and Houghton, K. and Spiegel, L. and Turvey, S.E. and Schmeling, H. and Lang, B. and Ellsworth, J. and Ramsey, S. and Bruns, A. and Campillo, S. and Benseler, S. and Ch{\'e}deville, G. and Schneider, R. and Yeung, R. and Duffy, C.M.
DOI: 10.1136/annrheumdis-2014-205372
2015

Association of health-related quality of life in childhood-onset systemic lupus erythematosus with ethnicity: Results from a multiethnic multicenter canadian cohort
Arthritis Care and Research
Levy, D.M. and Peschken, C.A. and Tucker, L.B. and Ch{\'e}deville, G. and Huber, A.M. and Pope, J.E. and Silverman, E.D. and Petty, R. and Cabral, D. and Houghton, K. and Morishita, K. and Campillo, S. and Duffy, K. and Scuccimarri, R. and Lang, B. and Ramsey, S. and Warner, A. and Ng, L. and Fortin, P. and Urowitz, M. and Gladman, D. and Albert, L. and Carette, S. and Inman, R. and McKenzie, T. and Clarke, A. and Pineau, C. and Bernatsky, S. and Tobaly, M. and Santopietro, T. and Smith, C.D. and Simpson, S. and Smith, K. and Zummer, M. and Ferland, D. and Arbillaga, H. and Wehlage, A. and Hudson, M. and Baron, M. and Berkson, L. and Bernstein, J. and Hanly, J. and Hewitt, S. and Ouimet, J. and Hitchon, C. and Craig, A. and Moyen, M.
DOI: 10.1002/acr.22363
2014

Skeletal findings in the first 12 months following initiation of glucocorticoid therapy for pediatric nephrotic syndrome
Osteoporosis International
Phan, V. and Blydt-Hansen, T. and Feber, J. and Alos, N. and Arora, S. and Atkinson, S. and Bell, L. and Clarson, C. and Couch, R. and Cummings, E.A. and Filler, G. and Grant, R.M. and Grimmer, J. and Hebert, D. and Lentle, B. and Ma, J. and Matzinger, M. and Midgley, J. and Pinsk, M. and Rodd, C. and Shenouda, N. and Stein, R. and Stephure, D. and Taback, S. and Williams, K. and Rauch, F. and Siminoski, K. and Ward, L.M. and Halton, J. and Jurencak, R. and Roth, J. and Moher, D. and Ramsay, T. and Kloiber, R. and Lewis, V. and Miettunen, P. and Cabral, D. and Dix, D.B. and Houghton, K. and Nadel, H.R. and Hay, J. and Cairney, E. and Sparrow, K. and Fernandez, C. and Huber, A.M. and Lang, B. and O{'}Brien, K. and Barr, R. and Coblentz, C. and Dent, P.B. and Larche, M. and Webber, C. and Abish, S. and Scuccimarri, R. and Glorieux, F. and Dubois, J. and Laverdi{\`e}re, C. and Saint-Cyr, C. and Ellsworth, J. and LeBlanc, C. and Wilson, B. and Charron, M. and Gaboury, I. and Israels, S. and Oen, K. and Reed, M.
DOI: 10.1007/s00198-013-2466-7
2014

Childhood regional conditions
Oxford Textbook of Rheumatology
Kristin Houghton
DOI: 10.1093/med/9780199642489.003.0158
10/2013

Evaluation of Static and Dynamic Postural Balance in Children With Juvenile Idiopathic Arthritis
Pediatric Physical Therapy
Kristin Michelle Houghton and Jaime Guzman
DOI: 10.1097/pep.0b013e31828a2978
2013

Glucocorticoid-related changes in body mass index among children and adolescents with rheumatic diseases
Arthritis Care and Research
Shiff, N.J. and Brant, R. and Guzman, J. and Cabral, D.A. and Huber, A.M. and Miettunen, P. and Roth, J. and Scuccimarri, R. and Alos, N. and Atkinson, S.A. and Collet, J.P. and Couch, R. and Cummings, E.A. and Dent, P.B. and Ellsworth, J. and Hay, J. and Houghton, K. and Jurencak, R. and Lang, B. and Larche, M. and Leblanc, C. and Rodd, C. and Saint-Cyr, C. and Stein, R. and Stephure, D. and Taback, S. and Rauch, F. and Ward, L.M.
DOI: 10.1002/acr.21785
2013

Evaluation of static and dynamic postural balance in children with juvenile idiopathic arthritis
Pediatric Physical Therapy
Houghton, K.M. and Guzman, J.
DOI: 10.1097/PEP.0b013e31828a2978
2013

Bodychecking in youth ice hockey
Paediatrics & Child Health
Kristin M Houghton and Carolyn A Emery
DOI: 10.1093/pch/17.9.509
11/2012

Physical Activity, Physical Fitness, and Exercise Therapy in Children with Juvenile Idiopathic Arthritis
The Physician and Sportsmedicine
Kristin Houghton
DOI: 10.3810/psm.2012.09.1979
09/2012

Exercise-induced intrapulmonary arteriovenous shunt in healthy women
Respiratory Physiology & Neurobiology
Jill M. Kennedy and Glen E. Foster and Michael S. Koehle and James E. Potts and George G.S. Sandor and M. Terri Potts and Kristin M. Houghton and William R. Henderson and A. William Sheel
DOI: 10.1016/j.resp.2012.01.004
04/2012

Corticosteroid related changes in body mass index in children and adolescents with rheumatic diseases
Pediatric Rheumatology
Natalie Shiff and Rollin Brant and David A Cabral and Jaime Guzman and Peter B Dent and Janet E Ellsworth and Kristin M Houghton and Adam Huber and Roman Jurencak and Bianca A Lang and Maggie Larche and Claire MA LeBlanc and Paivi M Miettunen and Kiem G Oen and Johannes Roth and Claire Saint-Cyr and Rosie Scuccimarri and Leanne M Ward and Canadian STOPP Consortium
DOI: 10.1186/1546-0096-10-s1-a11
2012

Healthy active living: Physical activity guidelines for children and adolescents
Paediatrics and Child Health
Lipnowski, S. and LeBlanc, C.M.A. and Bridger, T.L. and Houghton, K. and Philpott, J.F. and Templeton, C.G. and Warshawski, T.J. and Purcell, L.K.
DOI: 10.1093/pch/17.4.209
2012

Incident vertebral fractures among children with rheumatic disorders 12 months after glucocorticoid initiation: A national observational study
Arthritis Care and Research
Rodd, C. and Lang, B. and Ramsay, T. and Alos, N. and Huber, A.M. and Cabral, D.A. and Scuccimarri, R. and Miettunen, P.M. and Roth, J. and Atkinson, S.A. and Couch, R. and Cummings, E.A. and Dent, P.B. and Ellsworth, J. and Hay, J. and Houghton, K. and Jurencak, R. and Larch{\'e}, M. and LeBlanc, C. and Oen, K. and Saint-Cyr, C. and Stein, R. and Stephure, D. and Taback, S. and Lentle, B. and Matzinger, M. and Shenouda, N. and Moher, D. and Rauch, F. and Siminoski, K. and Ward, L.M.
DOI: 10.1002/acr.20589
2012

COMMENT
Journal of Musculoskeletal Pain
Alqanatish, J. and Petty, R. and Houghton, K. and Guzman, J.
DOI: 10.3109/10582452.2012.704146
2012

Incident vertebral fractures 12 months following glucocorticoid initiation in children with rheumatic disorders
Pediatric Rheumatology
Bianca A Lang and Celia Rodd and Timothy Ramsay and David A Cabral and Peter B Dent and Janet E Ellsworth and Kristin M Houghton and Adam Huber and Roman Jurencak and Maggie Larché and Claire MA LeBlanc and Brian Lentle and MaryAnn Matzinger and Paivi M Miettunen and Kiem Oen and Johannes Roth and Claire Saint-Cyr and Rosie Scuccimarri and Nazih Shenouda and Leanne M Ward and Canadian STOPP Consortium
DOI: 10.1186/1546-0096-10-s1-a75
2012

NONINFLAMMATORY MUSCULOSKELETAL PAIN CONDITIONS
Textbook of Pediatric Rheumatology
Claire LeBlanc and Kristin Houghton
DOI: 10.1016/b978-1-4160-6581-4.10047-0
2011

Policy statement - Boxing participation by children and adolescents
Pediatrics
McCambridge, T.M. and Brenner, J.S. and Benjamin, H.J. and Cappetta, C.T. and Demorest, R.A. and Halstead, M.E. and Koutures, C.G. and LaBella, C.R. and Labotz, M. and Loud, K. and Martin, S.S. and Weiss-Kelly, A. and Bridger, T. and Houghton, K. and LeBlanc, C. and Lipnowski, S. and Nieman, P. and Philpott, J.F. and Templeton, C. and Warshawski, T.
DOI: 10.1542/peds.2011-1165
2011

Childhood osseous sarcoidosis presenting with headache and lytic skull lesions
Journal of Clinical Rheumatology
Alqanatish, J.T. and Houghton, K.M. and Cairns, R.A.
DOI: 10.1097/RHU.0b013e31823b15ca
2011

Infrapatellar bursitis in children with juvenile idiopathic arthritis: A case series
Clinical Rheumatology
Alqanatish, J.T. and Petty, R.E. and Houghton, K.M. and Guzman, J. and Tucker, L.B. and Cabral, D.A. and Cairns, R.A.
DOI: 10.1007/s10067-010-1620-2
2011

Noninflammatory musculoskeletal pain conditions
Textbook of Pediatric Rheumatology
LeBlanc, C. and Houghton, K.
DOI: 10.1016/B978-1-4160-6581-4.10047-0
2011

Childhood Osseous Sarcoidosis Presenting With Headache and Lytic Skull Lesions
JCR: Journal of Clinical Rheumatology
Jubran Theeb Alqanatish and Kristin M. Houghton and Robyn A. Cairns
DOI: 10.1097/rhu.0b013e31823b15ca
2011

Rituximab Treatment in a Child with Rosai-Dorfman Disease and Systemic Lupus Erythematosus
The Journal of Rheumatology
J. T. ALQANATISH and K. HOUGHTON and M. BOND and C. SENGER and L. B. TUCKER
DOI: 10.3899/jrheum.091275
08/2010

Joint Communique: My Paralympics Experience
Canadian Rheumatology Association Journal
08/2010

Comparing Aerobic and Anaerobic Power during Upper and Lower Body Exercise in Pediatric Subjects
Medicine & Science in Sports & Exercise
James E. Potts and D. Kathryn Duff and Kristin M. Houghton and Astrid M. De Souza and Bonita J. Sawatzky and William A. Sheel
DOI: 10.1249/01.mss.0000386078.63883.8d
05/2010

Physical Activity Recommendations for Children With Specific Chronic Health Conditions: Juvenile Idiopathic Arthritis, Hemophilia, Asthma, and Cystic Fibrosis
Clinical Journal of Sport Medicine
John F Philpott and Kristin Houghton and Anthony Luke
DOI: 10.1097/jsm.0b013e3181d2eddd
05/2010

Physical activity recommendations for children with specific chronic health conditions: Juvenile idiopathic arthritis, hemophilia, asthma and cystic fibrosis
Paediatrics & Child Health
J Philpott and K Houghton and A Luke
DOI: 10.1093/pch/15.4.213
04/2010

Early outcomes and improvement of patients with juvenile idiopathic arthritis enrolled in a Canadian multicenter inception cohort
Arthritis Care & Research
Kiem Oen and Ciarán M. Duffy and Shirley M. L. Tse and Suzanne Ramsey and Janet Ellsworth and Gaëlle Chédeville and Anne-Laure Chetaille and Claire Saint-Cyr and David A. Cabral and Lynn R. Spiegel and Rayfel Schneider and Bianca Lang and Adam M. Huber and Paul Dancey and Earl Silverman and Alan M. Rosenberg and Bonnie Cameron and Nicole Johnson and Jean Dorval and Rosie Scuccimarri and Sarah Campillo and Ross E. Petty and Karen N. Watanabe Duffy and Gilles Boire and Elie Haddad and Kristin Houghton and Ronald Laxer and Stuart E. Turvey and Paivi Miettunen and Katherine Gross and Jaime Guzman and Susanne Benseler and Brian M. Feldman and Victor Espinosa and Rae S. M. Yeung and Lori Tucker
DOI: 10.1002/acr.20044
04/2010

Review for the generalist: evaluation of low back pain in children and adolescents
Pediatric Rheumatology
Kristin M Houghton
DOI: 10.1186/1546-0096-8-28
2010

Prevalent vertebral fractures among children initiating glucocorticoid therapy for the treatment of rheumatic disorders
Arthritis Care and Research
Huber, A.M. and Gaboury, I. and Cabral, D.A. and Lang, B. and Ni, A. and Stephure, D. and Taback, S. and Dent, P. and Ellsworth, J. and LeBlanc, C. and Saint-Cyr, C. and Scuccimarri, R. and Hay, J. and Lentle, B. and Matzinger, M. and Shenouda, N. and Moher, D. and Rauch, F. and Siminoski, K. and Ward, L.M. and Feber, J. and Halton, J. and Roth, J. and Kloiber, R. and Lewis, V. and Midgley, J. and Miettunen, P. and Dix, D.B. and Houghton, K. and Nadel, H.R. and White, C. and Clarson, C. and Stein, R. and Cairney, E. and Filler, G. and Grimmer, J. and Sparrow, K. and Cummings, E. and Fernandez, C. and O{'}Brien, K. and Ross, A. and Atkinson, S. and Arora, S. and Barr, R. and Coblentz, C. and Webber, C. and Rodd, C. and Abish, S. and Bell, L. and Glorieux, F. and Alos, N. and Dubois, J. and Laverdi{\`e}re, C. and Phan, V. and Couch, R. and Pinsk, M. and Wilson, B. and Grant, R. and Charron, M. and Hebert, D. and Blydt-Hansen, T. and Israels, S. and Oen, K. and Reed, M.
DOI: 10.1002/acr.20171
2010

Physical activity recommendations for children with specific chronic health conditions: Juvenile idiopathic arthritis, Hemophilia, Asthma, and Cystic fibrosis
Clinical Journal of Sport Medicine
Philpott, J.F. and Houghton, K. and Luke, A.
DOI: 10.1097/JSM.0b013e3181d2eddd
2010

Non-traumatic causes of musculoskeletal pain
Care of the Young Athlete, 2nd edition
2010

Cutaneous Polyarteritis Nodosa in Childhood: A Case Report and Review of the Literature
Arthritis
Nina-Karen Bansal and Kristin Michelle Houghton
DOI: 10.1155/2010/687547
2010

Predictors of early inactive disease in a juvenile idiopathic arthritis cohort: Results of a Canadian multicenter, prospective inception cohort study
Arthritis & Rheumatism
Kiem Oen and Lori Tucker and Adam M. Huber and Paivi Miettunen and Rosie Scuccimarri and Sarah Campillo and David A. Cabral and Brian M. Feldman and Shirley Tse and Gaëlle Chédeville and Lynn Spiegel and Rayfel Schneider and Bianca Lang and Janet Ellsworth and Suzanne Ramsey and Paul Dancey and Earl Silverman and Anne-Laure Chetaille and Bonnie Cameron and Nicole Johnson and Jean Dorval and Ross E. Petty and Karen Watanabe Duffy and Gilles Boire and Elie Haddad and Kristin Houghton and Claire Saint-Cyr and Stuart E. Turvey and Susanne Benseler and Mary Cheang and Rae S. M. Yeung and Ciarán M. Duffy
DOI: 10.1002/art.24539
08/2009

Access to Pediatric Rheumatology Subspecialty Care in British Columbia, Canada
The Journal of Rheumatology
N. J. SHIFF and R. ABDWANI and D. A. CABRAL and K. M. HOUGHTON and P. N. MALLESON and R. E. PETTY and V. M. ESPINOSA and L. B. TUCKER
DOI: 10.3899/jrheum.080514
02/2009

Acute epiglottitis as the initial presentation of pediatric Systemic Lupus Erythematosus
Pediatric Rheumatology
Sirirat Charuvanij and Kristin M Houghton
DOI: 10.1186/1546-0096-7-19
2009

Review for the generalist: Evaluation of pediatric hip pain
Pediatric Rheumatology
Houghton, K.M.
DOI: 10.1186/1546-0096-7-10
2009

Classification, presentation, and initial treatment of Wegener's granulomatosis in childhood
Arthritis and Rheumatism
Cabral, D.A. and Uribe, A.G. and Benseler, S. and O{'}Neil, K.M. and Hashkes, P.J. and Higgins, G. and Zeft, A.S. and Lovell, D.J. and Kingsbury, D.J. and Stevens, A. and McCurdy, D. and Chira, P. and Abramson, L. and Arkachaisri, T. and Campillo, S. and Eberhard, A. and Hersh, A.O. and Huber, A.M. and Kim, S. and Klein-Gitelman, M. and Levy, D.M. and Li, S.C. and Mason, T. and DeWitt, E.M. and Muscal, E. and Nassi, L. and Reiff, A. and Schikler, K. and Singer, N.G. and Wahezi, D. and Woodward, A. and Espinosa, V. and Guzman, J. and Houghton, K. and Malleson, P. and Petty, R. and Tucker, L. and Turvey, S. and Brooks, E.B. and Lesko, M. and Dedeoglu, F. and Fuhlbrigge, R. and Hazen, M. and Son, M.B. and Sundel, R. and Brown, D. and Shaham, B. and Cabrera, A. and Ilowite, N.T. and Hirsh, R. and Kietz, D. and Rosen, P. and Rosenkrank, M. and Torok, K. and Pachman, L. and Ali, A. and Brunner, H. and Griffin, T. and Grom, A. and Johnson, A. and Spalding, S. and Bork, D. and Ardoin, S. and Rabinovich, E. and Schanberg, L. and Wilder, R. and Lang, B.A. and Ramsey, S. and Stringer, E. and Warner, A. and Haines, K. and Kimura, Y. and Weiss, J. and Balboni, I. and Bromberg, R. and Cidon, M. and Frankovich, J. and Gerstbacher, D. and Hsu, J.J. and Lee, T. and Park, J.L. and Sandborg, C. and Song, S. and Reed, A. and Ch{\'e}deville, G. and Duffy, C. and Duffy, K. and Scuccimarri, R. and Gibbon, M. and Eichenfield, A. and Imundo, L. and Batres, C. and Bowyer, S. and Ballinger, S. and Klausmeier, T. and Hudgins, A. and Emery, H. and Hayward, K. and Inman, C. and Ringold, S. and Shaw, E. and Torgerson, T. and Turner, J. and Wallace, C. and Wargula, J. and Halford, S. and Myones, B.L. and Punaro, M. and Pascual, V. and von Scheven, E. and Michels, A. and Henrickson, M. and Jarvis, J. and Bonsack, J. and Prahalad, S.
DOI: 10.1002/art.24876
2009

Baseline Fitness Measures In A Cohort Of Obese Children
Medicine & Science in Sports & Exercise
James E. Potts and Astrid M. De Souza and Kristin M. Houghton and Shubhayan Sanatani and Walter J. Duncan and George G.S. Sandor
DOI: 10.1249/01.mss.0000322969.33832.31
05/2008

Development Of A Hospital-Based Exercise Prescription Clinic For Obese Children
Medicine & Science in Sports & Exercise
Astrid M. De Souza and Kristin M. Houghton and Shubhayan Sanatani and Walter J. Duncan and George G.S. Sandor and James E. Potts
DOI: 10.1249/01.mss.0000322970.10962.f9
05/2008

Fitness, fatigue, disease activity, and quality of life in pediatric lupus
Arthritis & Rheumatism
Kristin M. Houghton and Lori B. Tucker and James E. Potts and Donald C. Mckenzie
DOI: 10.1002/art.23534
2008

An adolescent with both Wegener's Granulomatosis and chronic blastomycosis
Pediatric Rheumatology
Abdwani, R. and Houghton, K. and Dobson, S. and O{'}Sullivan, M. and Malleson, P.
DOI: 10.1186/1546-0096-6-13
2008

Review for the generalist: Evaluation of pediatric foot and ankle pain
Pediatric Rheumatology
Houghton, K.M.
DOI: 10.1186/1546-0096-6-6
2008

Role of activity in health and its effect on morbidity and mortality in chronic rheumatic diseases of childhood
Occupational and Physical Therapy for Children with Rheumatic Diseases: A Clinical Handbook
2008

Aerobic and anaerobic capacity in Juvenile Idiopathic Arthritis: evaluation of the cardiorespiratory response
The Internet Journal of Rheumatology
DOI: 10.5580/201f
2008

Review for the generalist: evaluation of anterior knee pain
Pediatric Rheumatology
Kristin M Houghton
DOI: 10.1186/1546-0096-5-8
2007

Old challenges and new directions in pediatric rheumatology
Journal of Rheumatology
PubMed: 16395765
01/2006

Systemic lupus erythematosus in the pediatric North American Native population of British Columbia
Journal of Rheumatology
PubMed: 16395763
01/2006

Old challenges and new directions in pediatric rheumatology
Journal of Rheumatology
Cabral, D.A. and Laxer, R.M. and Schrader, J. and Turvey, S. and Stevens, A. and Yeung, R.S.M. and Foster, H.E. and Emery, H. and Prendiville, J. and Tucker, L.B. and Foeldvari, I. and Sherry, D.D. and Klinkhoff, A.B. and Wallace, C.A. and Houghton, K.
2006

Systemic lupus erythematosus in the pediatric North American native population of British Columbia
Journal of Rheumatology
Houghton, K.M. and Page, J. and Cabral, D.A. and Petty, R.E. and Tucker, L.B.
2006

Primary Sjogren’s syndrome in dizygotic adolescent twins: one case presentation with lymphocytic interstitial pneumonia
Journal of Rheumatology
PubMed: 16078341
08/2005

Primary Sjogren’s syndrome in children and adolescents: Are current diagnostic criteria valid?
Journal of Rheumatology
2005

Primary Sjögren's syndrome in dizygotic adolescent twins: One case with lymphocytic interstitial pneumonia
Journal of Rheumatology
Houghton, K.M. and Cabral, D.A. and Petty, R.E. and Tucker, L.B.
2005

Primary Sjögren's syndrome in children and adolescents: Are proposed diagnostic criteria applicable?
Journal of Rheumatology
Houghton, K. and Malleson, P. and Cabral, D. and Petty, R. and Tucker, L.
2005

Clinical trial of the sensitivity to tuberculin in children referred for evaluation of Kawasaki disease
Pediatric Rheumatology Online Journal
02/2004

Research

Aerobic and anaerobic exercise capacity in Juvenile Idiopathic Arthritis
Children with juvenile idiopathic arthritis (JIA) have lower physical fitness and lower peak oxygen consumption (VO2 peak) compared to healthy children. Suboptimal VO2 peak may be due to central limitations, characterized by suboptimal heart rate response, cardiac output (CO) or oxygen saturation; or peripheral limitations, characterized by high mixed venous oxygen content (low A-VO2).

In order to examine the cardiorespiratory response during aerobic exercise and the anaerobic to aerobic ratio (metabolic index), patients with JIA and age and sex matched controls are undergoing maximal aerobic and anaerobic exercise tests on a cycle ergometer.

During aerobic exercise we measure CO (litres/minute) with Doppler echocardiography. Arterial – mixed venous oxygen index (A-VO2) and systemic vascular resistance (SVR) are calculated. We hypothesize children with JIA will have lower VO2 peak and lower anaerobic fitness (peak power and total work) than their healthy age matched peers and that children with JIA will have a different cardiorespiratory response during maximal aerobic exercise tests compared to healthy age matched peers.

Children with JIA will have less efficient muscle oxygen utilization during maximal exercise, manifest by lower arterial – venous oxygen difference (A-VO2) (corresponding to higher mixed venous oxygen difference) at a given CO and higher systemic vascular resistance (SVR). We believe better understanding of the cardiorespiratory response during exercise will allow us to more effectively prescribe exercise in children with JIA.

Evaluation of dynamic postural balance using the Biodex Balance System® in children with Juvenile Idiopathic Arthritis
Children and adults with musculoskeletal lower limb injuries are known to lose postural balance. Balance training is now accepted by sports medicine physicians as a standard component of rehabilitation. Adults with arthritis are known to lose balance. It would seem reasonable, although it is not known, that children with arthritis affecting their lower limbs also lose balance.

In this pilot study we aim to evaluate and describe postural balance in a cohort of children with JIA and children without musculoskeletal disease or injury. This pilot will provide the framework for a randomized controlled trial to evaluate the role of balance training in rehabilitation of children with arthritis.

The pilot data will be sufficient to address the hypotheses that children with JIA have poor static and dynamic balance compared to healthy children and that lower extremity strength is positively correlated with static and dynamic balance.

The primary hypothesis of the ensuing intervention trial will be that children with JIA can improve their balance with postural balance training. We believe that balance training and assessment of children with JIA will allow counselling for increased and safe participation in physical activity, decrease the risks of injury and disability, and ultimately improve the quality of life of children with JIA for both the short and long term.

Balance training might also be valuable for children with other illnesses that cause interrupted optimal physical participation.

Honours & Awards

Principal applicant Kathryn Duff PhD. Co-applicants: James E Potts PhD, William Sheel PhD, Bonnie Sawatzky PhD, Astrid DeSouza MSc. Clinical Investigator Program; Royal College of Physicians and Surgeons Fellowship Program. University of British Columbia. Funding for July 2005 to January 2007. Project title: Aerobic capacity in juvenile idiopathic arthritis: central versus peripheral limitations.

Balance in children with Juvenile Idiopathic Arthritis. Equipment grant from the Abercrombie Foundation to purchase the Biodex Balance System® ($22,148.70).

Comparing aerobic and anaerobic power during upper and lower body exercise in pediatric subjects. Pediatric Exercise Working Group. Grant from College-Wide Fund for Scholarly Activity, Douglas College ($3000.00)

Research Group Members

Felice Mizan, Research Coordinator
Angelyne Rivera, Research Manager , Research Manager