Overview

My long-term research focus has been in clinical pharmacokinetics (drug disposition) and pharmacodynamics (drug action), particularly as these disciplines relate to: women's health; effects of gender, age, and other pathophysiologic states on pharmacokinetics and pharmacodynamics; and novel approaches to therapeutic drug monitoring. More recent interests include pharmacogenetics and pharmaceutical outcomes evaluations. Every day I use my clinical practice experiences to identify relevant pharmacokinetic and pharmacodynamic problems that are then studied through my laboratory-based research program. As an integrator who bridges the gap between the basic and clinical sciences, my goal for my research program is to address these clinical problems from a qualitative, quantitative, and mechanistic perspective and to make a difference in the health and well-being of patients (i.e. study results are directly and immediately incorporated into patient care).

Publications

Prevention and Treatment of Hyponatremia in Patients with Subarachnoid Hemorrhage: A Systematic Review.
World neurosurgery
Shah K, Turgeon RD, Gooderham PA, Ensom MHH
DOI: 10.1016/j.wneu.2017.09.182
PubMed: 28987848
01/2018

Penetration of Vancomycin into the Cerebrospinal Fluid: A Systematic Review.
Clinical Pharmacokinetics
Beach JE and Perrott J and Turgeon RD and Ensom MHH
DOI: 10.1007/s40262-017-0548-y
PubMed: 28528396
12/2017

Revolutionizing Therapeutic Drug Monitoring with the Use of Interstitial Fluid and Microneedles Technology
Pharmaceutics
Tony Kiang, Sahan Ranamukhaarachchi, Mary Ensom
DOI: 10.3390/pharmaceutics9040043
10/2017

Population Pharmacokinetics of Mycophenolic Acid: An Update
Clinical Pharmacokinetics
Tony K. L. Kiang, Mary H. H. Ensom
DOI: 10.1007/s40262-017-0593-6
08/2017

Evidence-Based Review of Pharmacotherapy Used for Parkinson's Disease Psychosis.
The Annals of pharmacotherapy
Wilby KJ, Johnson EG, Johnson HE, Ensom MHH
DOI: 10.1177/1060028017703992
PubMed: 28385039
08/2017

‘The bus analogy’: A new analogy to help pharmacy students conceptualize the well-stirred model
Currents in Pharmacy Teaching and Learning
Renée Dagenais, Arden R. Barry, Mary H.H. Ensom
DOI: 10.1016/j.cptl.2017.03.014
07/2017

Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Drugs in R&D
Renée Dagenais, Kyle John Wilby, Hazem Elewa, Mary H. H. Ensom
DOI: 10.1007/s40268-017-0195-7
07/2017

Vancomycin 50 mg/mL Suspension in Oral Syrup: Stability in Plastic Bottles and Syringes at 2 Temperatures
The Canadian Journal of Hospital Pharmacy
Alexander D Smith, Gemma Rempel, Andras Szeitz, Tara L Klassen, Mary H H Ensom
DOI: 10.4212/cjhp.v70i3.1665
06/2017

Pharmacokinetic Interactions between Valproic Acid and Lorazepam (PIVOtAL Study): A Review of Site-Specific Practices
The Canadian Journal of Hospital Pharmacy
Joane Y Tang, Tony K L Kiang, Mary H H Ensom
DOI: 10.4212/cjhp.v70i3.1656
06/2017

Levetiracetam Clinical Pharmacokinetic Monitoring in Pediatric Patients with Epilepsy
Clinical Pharmacokinetics
Jason Tan, Vanessa Paquette, Marc Levine, Mary H. H. Ensom
DOI: 10.1007/s40262-017-0537-1
03/2017

Combination of Ceftriaxone and Ampicillin for the Treatment of Enterococcal Endocarditis: A Qualitative Systematic Review
Annals of Pharmacotherapy
Shaylee C. Peterson, Tim T. Y. Lau, Mary H. H. Ensom
DOI: 10.1177/1060028017692357
02/2017

Clinical Pharmacokinetic Monitoring of Leflunomide in Renal Transplant Recipients with BK Virus Reactivation: A Review of the Literature
Clinical Pharmacokinetics
Joan C. Y. Ng, Marianna Leung, Alissa J. Wright, Mary H. H. Ensom
DOI: 10.1007/s40262-017-0521-9
02/2017

Immunosuppressants: Cyclosporine, Tacrolimus, Sirolimus, and Mycophenolate
Winter’s Basic Clinical Pharmacokinetics
2017

Antirejection Agents
Clinical Pharmacokinetics
2017

Systematic Review of Efficacy, Pharmacokinetics, and Administration of Intraventricular Aminoglycosides in Adults.
Neurocritical care
LeBras M, Chow I, Mabasa VH, Ensom MH
DOI: 10.1007/s12028-016-0269-3
PubMed: 27043949
12/2016

Magnocaine: Physical Compatibility and Chemical Stability of Magnesium Sulphate and Lidocaine Hydrochloride in Prefilled Syringes.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Houlihan S, Decarie D, Benes C, Cleve R, Vidler M, Magee LA, Ensom MHH, von Dadelszen P
DOI: 10.1016/j.jogc.2016.04.097
PubMed: 27720093
10/2016

Predictive Performance of the Winter–Tozer and Derivative Equations for Estimating Free Phenytoin Concentration
The Canadian Journal of Hospital Pharmacy
Wendy Cheng, Tony K L Kiang, Penny Bring, Mary H H Ensom
DOI: 10.4212/cjhp.v69i4.1573
08/2016

Therapeutic drug monitoring of mycophenolate in adult solid organ transplant patients: an update
Expert Opinion on Drug Metabolism & Toxicology
Tony K. L. Kiang, Mary H. H. Ensom
DOI: 10.1517/17425255.2016.1170806
04/2016

Stability of Extemporaneously Compounded Trimethoprim in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie
DOI: 10.4212/cjhp.v69i2.1547
04/2016

Paving the Way and Passing the Torch
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom
DOI: 10.4212/cjhp.v69i2.1535
04/2016

Why Does a High Extraction Ratio Drug Given Orally Behave Like a Low Extraction Ratio Drug? – An Intuitive Explanation
UBC Pharmaceutical Sciences Student Journal
03/2016

Dexamethasone 1 mg/mL Suspension Prepared from Crushed Tablets: Stability in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie
DOI: 10.4212/cjhp.v69i1.1524
03/2016

Opioid Pharmacokinetics-PharmacodynamicsClinical Implications in Acute Pain Management in Trauma
Annals of Pharmacotherapy
Meghan MacKenzie, Peter J. Zed, Mary H. H. Ensom
DOI: 10.1177/1060028015625659
01/2016

A Comprehensive Review on the Predictive Performance of the Sheiner-Tozer and Derivative Equations for the Correction of Phenytoin Concentrations
Annals of Pharmacotherapy
Tony K. L. Kiang, Mary H. H. Ensom
DOI: 10.1177/1060028016628166
01/2016

Clinical Significant Interactions with Opioid Analgesics
Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents
Tony K. L. Kiang and Mary H. H. Ensom
DOI: 10.1007/978-3-319-27883-4_20
2016

Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs
DOI: 10.1007/978-981-10-2113-8
2016

A Qualitative Review on the Pharmacokinetics of Antibiotics in Saliva: Implications on Clinical Pharmacokinetic Monitoring in Humans
Clinical Pharmacokinetics
Tony K. L. Kiang, Mary H. H. Ensom
DOI: 10.1007/s40262-015-0321-z
09/2015

Pediatric Obesity: Pharmacokinetics and Implications for Drug Dosing
Clinical Therapeutics
Jennifer G. Kendrick, Roxane R. Carr, Mary H.H. Ensom
DOI: 10.1016/j.clinthera.2015.05.495
09/2015

Stability of Extemporaneously Compounded Levetiracetam in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie
DOI: 10.4212/cjhp.v68i4.1480
08/2015

A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children
Clinical Pharmacokinetics
Kyle John Wilby, Sara Shabana, Mary H. H. Ensom, Fawziah Marra
DOI: 10.1007/s40262-015-0303-1
07/2015

Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement.
Clinical pharmacokinetics
Kanji S, Hayes M, Ling A, Shamseer L, Chant C, Edwards DJ, Edwards S, Ensom MH, Foster DR, Hardy B, Kiser TH, la Porte C, Roberts JA, Shulman R, Moher D
DOI: 10.1007/s40262-015-0236-8
PubMed: 25637173
07/2015

Therapeutic Drug Monitoring of Voriconazole in the Management of Invasive Fungal Infections: A Critical Review
Clinical Pharmacokinetics
Hazem Elewa, Eman El-Mekaty, Ahmed El-Bardissy, Mary H. H. Ensom, Kyle John Wilby
DOI: 10.1007/s40262-015-0297-8
06/2015

Pediatric Assessment of Vancomycin Empiric Dosing (PAVED): a Retrospective Review.
Paediatric drugs
Rainkie D, Ensom MH, Carr R
DOI: 10.1007/s40272-015-0122-8
PubMed: 25813682
06/2015

Antiviral Treatment of Bell's Palsy Based on Baseline Severity: A Systematic Review and Meta-analysis
The American Journal of Medicine
Ricky D. Turgeon, Kyle J. Wilby, Mary H.H. Ensom
DOI: 10.1016/j.amjmed.2014.11.033
06/2015

A Critical Review on the Clinical Pharmacokinetics, Pharmacodynamics, and Clinical Trials of Ceftaroline
Clinical Pharmacokinetics
Tony K. L. Kiang, Kyle J. Wilby, Mary H. H. Ensom
DOI: 10.1007/s40262-015-0281-3
05/2015

A Review of Pharmacokinetic Drug–Drug Interactions with the Anthelmintic Medications Albendazole and Mebendazole
Clinical Pharmacokinetics
Shane Ashley Pawluk, Craig Allan Roels, Kyle John Wilby, Mary H. H. Ensom
DOI: 10.1007/s40262-015-0243-9
02/2015

Vancomycin Loading DosesA Systematic Review
Annals of Pharmacotherapy
Jillian Reardon, Tim T. Y. Lau, Mary H. H. Ensom
DOI: 10.1177/1060028015571163
02/2015

Measuring Anti–Factor Xa Activity to Monitor Low-Molecular-Weight Heparin in Obesity: A Critical Review
The Canadian Journal of Hospital Pharmacy
Gregory Egan, Mary H H Ensom
DOI: 10.4212/cjhp.v68i1.1423
02/2015

Stability of Dabigatran Etexilate in Manufacturer’s Blister Pack, Unit-Dose Packaging, and Community Pharmacy Blister Pack
The Canadian Journal of Hospital Pharmacy
Erica H Z Wang, Jennifer L Bolt, Diane Décarie, William Semchuk, Mary H H Ensom
DOI: 10.4212/cjhp.v68i1.1420
02/2015

Lacosamide as adjunctive therapy in refractory epilepsy in adults: A systematic review
Seizure
Vanessa Paquette, Celia Culley, Erica D. Greanya, Mary H.H. Ensom
DOI: 10.1016/j.seizure.2014.11.007
02/2015

Evaluating Outcomes of Alternative Dosing Strategies for CefepimeA Qualitative Systematic Review
Annals of Pharmacotherapy
Sarah V. Burgess, Vincent H. Mabasa, Ivy Chow, Mary H. H. Ensom
DOI: 10.1177/1060028014564179
01/2015

Use of Proton Pump Inhibitors in the Management of Gastroesophageal VaricesA Systematic Review
Annals of Pharmacotherapy
Elaine A. G. Lo, Kyle J. Wilby, Mary H. H. Ensom
DOI: 10.1177/1060028014559244
01/2015

Clinical Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antimalarials
Tony K.L. Kiang, Kyle John Wilby, Mary H.H. Ensom
DOI: 10.1007/978-3-319-10527-7
2015

Stability of Extemporaneously Compounded Naproxen 25 mg/mL Suspension in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie, Karen Lingertat-Walsh
DOI: 10.4212/cjhp.v68i6.1509
2015

Stability of Extemporaneously Compounded Pyridoxine in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie
DOI: 10.4212/cjhp.v67i5.1396
10/2014

Stability of Extemporaneously Compounded Dexamethasone in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie
DOI: 10.4212/cjhp.v67i4.1371
08/2014

Review of Evidence for Measuring Drug Concentrations of First-Line Antitubercular Agents in Adults
Clinical Pharmacokinetics
Kyle John Wilby, Mary H. H. Ensom, Fawziah Marra
DOI: 10.1007/s40262-014-0170-1
08/2014

Stability of Extemporaneously Compounded Clonidine in Glass and Plastic Bottles and Plastic Syringes
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Décarie
DOI: 10.4212/cjhp.v67i4.1377
08/2014

Stability of Epinephrine at Standard Concentrations
The Canadian Journal of Hospital Pharmacy
Roxane R Carr, Diane Decarie, Mary H H Ensom
DOI: 10.4212/cjhp.v67i3.1356
06/2014

A Comprehensive Review on the Pharmacokinetics of Antibiotics in Interstitial Fluid Spaces in Humans: Implications on Dosing and Clinical Pharmacokinetic Monitoring
Clinical Pharmacokinetics
Tony K. L. Kiang, Urs O. Häfeli, Mary H. H. Ensom
DOI: 10.1007/s40262-014-0152-3
06/2014

Identification of Risk Factors for Nephrotoxicity in Patients Receiving Extended-Duration, High-Trough Vancomycin Therapy
The Canadian Journal of Hospital Pharmacy
Claire Contreiras, Michael Legal, Tim T Y Lau, Rosanne Thalakada, Stephen Shalansky, Mary H H Ensom
DOI: 10.4212/cjhp.v67i2.1340
04/2014

Stability of clonidine suspension in oral plastic syringes
American Journal of Health-System Pharmacy
C. Ma, D. Decarie, M. H. H. Ensom
DOI: 10.2146/ajhp130480
03/2014

Systematic review of efficacy, pharmacokinetics, and administration of intraventricular vancomycin in adults.
Neurocritical care
Ng K, Mabasa VH, Chow I, Ensom MH
DOI: 10.1007/s12028-012-9784-z
PubMed: 23090839
02/2014

Standard-Dose Versus High-Dose Acyclovir in Children Treated Empirically for Encephalitis: A Retrospective Cohort Study of Its Use and Safety
Pediatric Drugs
Jennifer G. Kendrick, Mary H. H. Ensom, Andrew Steer, Colin T. White, Eddie Kwan, Roxane R. Carr
DOI: 10.1007/s40272-014-0066-4
02/2014

Forty-Five Years of the CJHP: Never Closed, Always Renovating
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom
DOI: 10.4212/cjhp.v67i6.1400
2014

Gender, smoking and tobacco reduction and cessation: a scoping review.
International journal for equity in health
Bottorff JL, Haines-Saah R, Kelly MT, Oliffe JL, Torchalla I, Poole N, Greaves L, Robinson CA, Ensom MH, Okoli CT, Phillips JC
DOI: 10.1186/s12939-014-0114-2
PubMed: 25495141
2014

Applying the Principles of Disease Screening to the Prostate Cancer Debate
UBC Pharmaceutical Sciences Student Journal
2014

Clinical Pharmacokinetic Drug Interactions Associated with Artemisinin Derivatives and HIV-Antivirals
Clinical Pharmacokinetics
Tony K. L. Kiang, Kyle J. Wilby, Mary H. H. Ensom
DOI: 10.1007/s40262-013-0110-5
10/2013

Compatibility and Stability of Morphine Sulphate and Naloxone Hydrochloride in 0.9% Sodium Chloride for Injection
The Canadian Journal of Hospital Pharmacy
Charlotte Kistner, Mary H H Ensom, Diane Decarie, Gillian Lauder, Roxane R Carr
DOI: 10.4212/cjhp.v66i3.1253
06/2013

Addition of Rifampin to Vancomycin for Methicillin-Resistant Staphylococcus aureus Infections: What Is the Evidence?
Annals of Pharmacotherapy
Simon Tremblay, Tim TY Lau, Mary HH Ensom
DOI: 10.1345/aph.1r726
05/2013

Stability of Propranolol in Extemporaneously Compounded Suspensions
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Jennifer Kendrick, Susan Rudolph, Diane Decarie
DOI: 10.4212/cjhp.v66i2.1234
04/2013

Telaprevir: Clinical Pharmacokinetics, Pharmacodynamics, and Drug–Drug Interactions
Clinical Pharmacokinetics
Tony K. L. Kiang, Kyle J. Wilby, Mary H. H. Ensom
DOI: 10.1007/s40262-013-0053-x
04/2013

Effect of the UGT1A1*28 Allele on Unconjugated Hyperbilirubinemia in HIV-Positive Patients Receiving Atazanavir: A Systematic Review
Annals of Pharmacotherapy
Celia L Culley, Tony KL Kiang, Samuel E Gilchrist, Mary HH Ensom
DOI: 10.1345/aph.1r550
04/2013

Serotonergic and Adrenergic Drug Interactions Associated with Linezolid: A Critical Review and Practical Management Approach
Annals of Pharmacotherapy
Tasha D Ramsey, Tim TY Lau, Mary HH Ensom
DOI: 10.1345/aph.1r604
04/2013

A Review of the Pharmacokinetic Implications of Schistosomiasis
Clinical Pharmacokinetics
Kyle J. Wilby, Samuel E. Gilchrist, Mary H. H. Ensom
DOI: 10.1007/s40262-013-0055-8
03/2013

What Will It Take? The Quest to Achieve Indexing by the National Library of Medicine
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom
DOI: 10.4212/cjhp.v66i1.1204
03/2013

Pharmacogenetics of Risperidone: A Systematic Review of the Clinical Effects of CYP2D6 Polymorphisms
Annals of Pharmacotherapy
Andrea L Cartwright, Kyle J Wilby, Susan Corrigan, Mary HH Ensom
DOI: 10.1345/aph.1r333
03/2013

Pharmacokinetic Profile of Artemisinin Derivatives and Companion Drugs Used in Artemisinin-Based Combination Therapies for the Treatment of Plasmodium falciparum Malaria in Children
Clinical Pharmacokinetics
Shane A. Pawluk, Kyle J. Wilby, Mary H. H. Ensom
DOI: 10.1007/s40262-012-0026-5
01/2013

Multiple Regression Analysis of Factors Predicting Mycophenolic Acid Free Fraction in 91 Adult Organ Transplant Recipients
Therapeutic Drug Monitoring
Tony K. L. Kiang, Karen Ng, Mary H. H. Ensom
DOI: 10.1097/ftd.0b013e318299fa38
2013

Dosing and Monitoring of Methadone in Pregnancy: Literature Review
The Canadian Journal of Hospital Pharmacy
Jennifer R Shiu, Mary H H Ensom
DOI: 10.4212/cjhp.v65i5.1176
10/2012

Fundamentals of Population Pharmacokinetic ModellingValidation Methods
Clinical Pharmacokinetics
Catherine M.T Sherwin, Tony K.L. Kiang, Michael G. Spigarelli, Mary H.H. Ensom
DOI: 10.2165/11634200-000000000-00000
09/2012

Fundamentals of Population Pharmacokinetic ModellingModelling and Software
Clinical Pharmacokinetics
Tony K.L. Kiang, Catherine M.T Sherwin, Michael G. Spigarelli, Mary H.H. Ensom
DOI: 10.2165/11634080-000000000-00000
08/2012

Development and Validation of a Novel Vancomycin Dosing Nomogram for Achieving High-Target Trough Levels at 2 Canadian Teaching Hospitals
The Canadian Journal of Hospital Pharmacy
Rosanne Thalakada, Michael Legal, Tim T Y Lau, Tiffany Luey, Josh Batterink, Mary H H Ensom
DOI: 10.4212/cjhp.v65i3.1140
06/2012

An overlooked majority: HIV-positive gay men who smoke
Journal of Men's Health
J. Craig Phillips, John L. Oliffe, Mary H.H. Ensom, Joan L. Bottorff, Laura J.L. Bissell, Jack Boomer, Kerry MacKelvie O’Brien, Terry Howard, Milan Khara
DOI: 10.1016/j.jomh.2011.11.003
03/2012

Mosquirix (RTS,S): A Novel Vaccine for the Prevention of Plasmodium falciparum Malaria
Annals of Pharmacotherapy
K. J. Wilby, T. T. Lau, S. E. Gilchrist, M. H. Ensom
DOI: 10.1345/aph.1aq634
03/2012

The Role of Therapeutic Drug Monitoring of Imatinib in Patients with Chronic Myeloid Leukemia and Metastatic or Unresectable Gastrointestinal Stromal Tumors
Therapeutic Drug Monitoring
Jennifer F T Teng, Vincent H Mabasa, Mary H H Ensom
DOI: 10.1097/ftd.0b013e31823cdec9
02/2012

Pharmacokinetics of tacrolimus and mycophenolate mofetil in renal transplant recipients on a corticosteroid-free regimen.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Greanya ED, Poulin E, Partovi N, Shapiro RJ, Al-Khatib M, Ensom MH
DOI: 10.2146/ajhp110287
PubMed: 22215359
01/2012

A systematic review of the pharmacokinetics of antiepileptic drugs in neonates with refractory seizures.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Tulloch JK, Carr RR, Ensom MH
DOI: 10.5863/1551-6776-17.1.31
PubMed: 23118657
01/2012

Belatacept: A New Biologic and Its Role in Kidney Transplantation
Annals of Pharmacotherapy
Victoria CH Su, Jennifer Harrison, Christin Rogers, Mary HH Ensom
DOI: 10.1345/aph.1q537
01/2012

Pharmacokinetic Effects of Bariatric Surgery
Annals of Pharmacotherapy
Allan Edwards, Mary HH Ensom
DOI: 10.1345/aph.1q414
01/2012

Evaluating Outcomes Associated with Alternative Dosing Strategies for Piperacillin/Tazobactam: A Qualitative Systematic Review
Annals of Pharmacotherapy
G. T. Mah, V. H. Mabasa, I. Chow, M. H. Ensom
DOI: 10.1345/aph.1q378
01/2012

The Impact of Obesity on Pharmacokinetics and Dosing of Leukemia Chemotherapy
Energy Balance and Hematologic Malignancies
Jennifer Kendrick, Dawn Warkentin, Mary H. H. Ensom
DOI: 10.1007/978-1-4614-2403-1_5
2012

Therapeutic Drug Monitoring in Interstitial Fluid: A Feasibility Study Using a Comprehensive Panel of Drugs
Journal of Pharmaceutical Sciences
Tony K.L. Kiang, Veronika Schmitt, Mary H.H. Ensom, Beverly Chua, Urs O. Häfeli
DOI: 10.1002/jps.23309
2012

Pharmacokinetics of Antimalarials in PregnancyA Systematic Review
Clinical Pharmacokinetics
Kyle J. Wilby, Mary H.H. Ensom
DOI: 10.2165/11594550-000000000-00000
11/2011

Haloperidol Dosing Strategies in the Treatment of Delirium in the Critically-Ill
Neurocritical Care
Erica H. Z. Wang, Vincent H. Mabasa, Gabriel W. Loh, Mary H. H. Ensom
DOI: 10.1007/s12028-011-9643-3
10/2011

A two-center study on the pharmacokinetics of intravenous immunoglobulin before and during pregnancy in healthy women with poor obstetrical histories.
Human reproduction (Oxford, England)
Ensom MH, Stephenson MD
DOI: 10.1093/humrep/der227
PubMed: 21771770
09/2011

Pharmacokinetics of aminoglycosides in patients with chronic spinal cord injury
American Journal of Health-System Pharmacy
F. Young, M. H. H. Ensom
DOI: 10.2146/ajhp100473
08/2011

Does Olanzapine Warrant Clinical Pharmacokinetic Monitoring in Schizophrenia?
Clinical Pharmacokinetics
Erin Schwenger, Jane Dumontet, Mary H.H. Ensom
DOI: 10.2165/11587240-000000000-00000
07/2011

Stability of Levetiracetam in Extemporaneously Compounded Suspensions
The Canadian Journal of Hospital Pharmacy
Mary H.H. Ensom, Diane Decarie, Susan Rudolph
DOI: 10.4212/cjhp.v64i3.1024
06/2011

Extended-Interval Aminoglycoside Therapy for Adult Patients with Febrile Neutropenia: A Systematic Review
The Canadian Journal of Hospital Pharmacy
Sarah N. Stabler, Mary H. H. Ensom
DOI: 10.4212/cjhp.v64i3.1020
06/2011

Risperidone in Schizophrenia: Is There a Role for Therapeutic Drug Monitoring?
Therapeutic Drug Monitoring
Katherine Seto, Jane Dumontet, Mary H H Ensom
DOI: 10.1097/ftd.0b013e3182126d83
06/2011

Sex differences in smoking cessation outcomes of a tailored program for individuals with substance use disorders and mental illness
Addictive Behaviors
Chizimuzo T.C. Okoli, Milan Khara, Iris Torchalla, Mary H.H. Ensom, John L. Oliffe, Joan L. Bottorff, Paul J Stanley
DOI: 10.1016/j.addbeh.2010.12.029
05/2011

Vancomycin-Induced Neutropenia: Is it Dose- or Duration-Related?
Annals of Pharmacotherapy
Emily Black, Tim TY Lau, Mary HH Ensom
DOI: 10.1345/aph.1p583
04/2011

Mycophenolate monitoring in liver, thoracic, pancreas, and small bowel transplantation: a consensus report.
Transplantation reviews (Orlando, Fla.)
Cantarovich M, Brown NW, Ensom MH, Jain A, Kuypers DR, Van Gelder T, Tredger JM
DOI: 10.1016/j.trre.2010.12.001
PubMed: 21454066
04/2011

Impact of Mycophenolate Mofetil Dose Reduction on Allograft Outcomes in Kidney Transplant Recipients on Tacrolimus-Based Regimens: A Systematic Review
Annals of Pharmacotherapy
Victoria CH Su, Erica D Greanya, Mary HH Ensom
DOI: 10.1345/aph.1p456
02/2011

Development and Validation of Limited Sampling Strategies for Tacrolimus and Mycophenolate in Steroid-Free Renal Transplant Regimens
Therapeutic Drug Monitoring
Eric Poulin, Erica D Greanya, Nilufar Partovi, R Jean Shapiro, Mai Al-Khatib, Mary H H Ensom
DOI: 10.1097/ftd.0b013e3182028b23
02/2011

Comparison of vancomycin concentrations in blood and interstitial fluid: a possible model for less invasive therapeutic drug monitoring
Clinical Chemistry and Laboratory Medicine (CCLM)
Urs O. Häfeli, Mary H.H. Ensom, Tony K.L. Kiang, Boris Stoeber, Beverly A. Chua, Morris Pudek, Veronika Schmitt
DOI: 10.1515/cclm.2011.727
01/2011

A New Analogy for Teaching the Well-Stirred Model to Pharmacy Students
The International Journal of Pharmacy Education and Practice
2011

Evaluation of the Research Grant Program of the Foundation of the Canadian Society of Hospital Pharmacists, 1995–2008
The Canadian Journal of Hospital Pharmacy
Peter J Zed, Mary H H Ensom, Richard S Slavik, Kerry Wilbur, Salmaan Kanji, Sheri L Koshman, Janice Irvine-Meek, Marc Perreault, Sheryl Zelenitsky
DOI: 10.4212/cjhp.v64i6.1080
2011

Improving the Chances of Manuscript Acceptance: How to Address Peer Reviewers’ Comments
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom
DOI: 10.4212/cjhp.v64i6.1079
2011

Pharmacogenetic Impact of UDP-Glucuronosyltransferase Metabolic Pathway and Multidrug Resistance–Associated Protein 2 Transport Pathway on Mycophenolic Acid in Thoracic Transplant Recipients: An Exploratory Study
Pharmacotherapy
Lillian S. L Ting, Marie-Odile Benoit-Biancamano, Olivier Bernard, K. Wayne Riggs, Chantal Guillemette, Mary H. H Ensom
DOI: 10.1592/phco.30.11.1097
11/2010

Stability of Vancomycin 25 mg/mL in Ora-Sweet and Water in Unit-Dose Cups and Plastic Bottles at 4°C and 25°C
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Decarie, Anisha Lakhani
DOI: 10.4212/cjhp.v63i5.948
10/2010

Comparison of Continuous and Intermittent IV Infusion of Vancomycin: Systematic Review
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Sally S K Man, Roxane R Carr
DOI: 10.4212/cjhp.v63i5.949
10/2010

Facts and Comparisons: Journal Updates and Performance Indicators
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom
DOI: 10.4212/cjhp.v63i4.930
08/2010

Pharmacokinetics of Mycophenolic Acid and its Glucuronidated Metabolites in Stable Islet Transplant Recipients
Therapeutic Drug Monitoring
Mai Al-Khatib, R Jean Shapiro, Nilufar Partovi, Lillian S L Ting, Mary H H Ensom
DOI: 10.1097/ftd.0b013e3181d80c1b
06/2010

Therapeutic drug monitoring in the neurocritical care unit
Current Opinion in Critical Care
Gabriel W Loh, Vincent H Mabasa, Mary HH Ensom
DOI: 10.1097/mcc.0b013e3283374e3c
04/2010

Pharmacokinetics and drug dosing in obese children.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Kendrick JG, Carr RR, Ensom MH
PubMed: 22477800
04/2010

Is There a Role for Therapeutic Drug Monitoring of Vitamin D Level as a Surrogate Marker for Fracture Risk?
Pharmacotherapy
Jennifer E Isenor, Mary H. H Ensom
DOI: 10.1592/phco.30.3.254
03/2010

Comparing Outcomes of Meropenem Administration Strategies Based on Pharmacokinetic and Pharmacodynamic Principles: A Qualitative Systematic Review
Annals of Pharmacotherapy
Jerrold Perrott, Vincent H Mabasa, Mary HH Ensom
DOI: 10.1345/aph.1m339
02/2010

Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation.
Clinical journal of the American Society of Nephrology : CJASN
Kuypers DR, Le Meur Y, Cantarovich M, Tredger MJ, Tett SE, Cattaneo D, Tönshoff B, Holt DW, Chapman J, Gelder Tv, Transplantation Society (TTS) Consensus Group on TDM of MPA
DOI: 10.2215/cjn.07111009
PubMed: 20056756
02/2010

Does Valproic Acid Warrant Therapeutic Drug Monitoring in Bipolar Affective Disorder?
Therapeutic Drug Monitoring
Jennifer Haymond, Mary H H Ensom
DOI: 10.1097/ftd.0b013e3181c13a30
02/2010

Limited Sampling Strategies for Predicting Area Under the Concentration-Time Curve of Mycophenolic Acid in Islet Transplant Recipients
Annals of Pharmacotherapy
Mai Al-Khatib, R Jean Shapiro, Nilufar Partovi, Lillian SL Ting, Marc Levine, Mary HH Ensom
DOI: 10.1345/aph.1m511
01/2010

Concepts in Pharmacogenomics.
The Canadian journal of hospital pharmacy
Ensom MHH
2010

Research and Scholarship for Researcher-Educator Faculty: Top 10 Survival Tips.
Clinical Faculty Survival Guide
2010

Stability of Levothyroxine in Sodium Chloride for IV Administration
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Dawn K Strong, Diane Decarie
DOI: 10.4212/cjhp.v63i6.963
2010

The Utility of Therapeutic Drug Monitoring for Ribavirin in Patients with Chronic Hepatitis C—A Critical Review
Annals of Pharmacotherapy
Alice HW Chan, Nilufar Partovi, Mary HH Ensom
DOI: 10.1345/aph.1m225
11/2009

Overcoming Barriers to Adoption of Guidelines and Use of Proven Interventions: It My Table!
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom
DOI: 10.4212/cjhp.v62i5.820
09/2009

Limited-Sampling Strategies for Anti-Infective Agents: Systematic Review
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Denise A Sprague
DOI: 10.4212/cjhp.v62i5.827
09/2009

Limited sampling strategies for mycophenolic acid in solid organ transplantation: a systematic review
Expert Opinion on Drug Metabolism & Toxicology
Nicole K Bruchet, Mary HH Ensom
DOI: 10.1517/17425250903114182
08/2009

A Critical Review: Does Thiopental Continuous Infusion Warrant Therapeutic Drug Monitoring in the Critical Care Population?
Therapeutic Drug Monitoring
Fong Huynh, Vincent H Mabasa, Mary H H Ensom
DOI: 10.1097/ftd.0b013e318196fb9f
04/2009

Stability of Hydromorphone–Ketamine Solutions in Glass Bottles, Plastic Syringes, and IV Bags for Pediatric Use
The Canadian Journal of Hospital Pharmacy
Mary H H Ensom, Diane Decarie, Karen Leung, Carolyne Montgomery
DOI: 10.4212/cjhp.v62i2.439
04/2009

Utility of Limited Sampling Strategies for Anticancer Agents in the Clinical Arena: A Systematic Review
Current Cancer Therapy Reviews
Rumi Pattar, Mary Ensom
DOI: 10.2174/157339409787314081
02/2009

Role of Therapeutic Drug Monitoring of Voriconazole in the Treatment of Invasive Fungal Infections
The Canadian Journal of Hospital Pharmacy
I Fan Kuo, Mary H H Ensom
DOI: 10.4212/cjhp.v62i6.845
2009

Education of pharmacists in Canada.
American Journal of Pharmaceutical Education
Austin Z, Ensom MH
DOI: 10.5688/aj7206128
PubMed: 19325948
12/2008

Utility of monitoring mycophenolic acid in solid organ transplant patients
Clinical Biochemistry
J. Zeidler, C. Balion, M. Oremus, M.H.H. Ensom, M. Matsuda-Abedini, L. Booker, C. Archer, P. Raina
DOI: 10.1016/j.clinbiochem.2008.08.003
10/2008

Pharmacokinetics of Mycophenolic Acid and its Phenolic-Glucuronide and Acyl Glucuronide Metabolites in Stable Thoracic Transplant Recipients
Therapeutic Drug Monitoring
Lillian S L Ting, Nilufar Partovi, Robert D Levy, K Wayne Riggs, Mary H H Ensom
DOI: 10.1097/ftd.0b013e318166eba0
06/2008

Corticosteroid Interactions with Cyclosporine, Tacrolimus, Mycophenolate, and Sirolimus: Fact or Fiction?
Annals of Pharmacotherapy
S. Lam, N. Partovi, L. S. Ting, M. H. Ensom
DOI: 10.1345/aph.1k628
05/2008

From Emoticons to CJHP (editorial)
Canadian Journal of Hospital Pharmacy
04/2008

Performance of Limited Sampling Strategies for Predicting Mycophenolic Acid Area Under the Curve in Thoracic Transplant Recipients
The Journal of Heart and Lung Transplantation
Lillian S.L. Ting, Nilufar Partovi, Robert D. Levy, Andrew P. Ignaszewski, Mary H.H. Ensom
DOI: 10.1016/j.healun.2007.12.009
03/2008

Use of Dietary Supplements by Patients Taking Digoxin
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v61i1.8
02/2008

Does Oxcarbazepine Warrant Therapeutic Drug Monitoring?A Critical Review
Clinical Pharmacokinetics
Penny Bring, Mary H H Ensom
DOI: 10.2165/0003088-200847120-00002
2008

Will Genetic Testing for Warfarin Dosing Ever be Ready for Prime Time?
Pharmacotherapy
2008

Aminoglycosides in Combination Therapy with beta-lactams for Staphylococcus aureus Endocarditis: A Systematic Review
Canadian Journal of Hospital Pharmacy
DOI: 10.1.1.1024.7532
11/2007

Stability of Lansoprazole in Extemporaneously Compounded Suspensions for Nasogastric or Oral Administration
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v60i3.173
06/2007

Clinical Pharmacokinetic Monitoring of Midazolam in Critically Ill Patients
Pharmacotherapy
Sean P Spina, Mary H. H Ensom
DOI: 10.1592/phco.27.3.389
03/2007

Effect of Acidification on Protein Binding of Mycophenolic Acid
Therapeutic Drug Monitoring
Lillian SL Ting, Diane Decarie, Mary HH Ensom
DOI: 10.1097/01.ftd.0000255011.75863.15
02/2007

Modelling costs and outcomes of expanded availability of emergency contraceptive use in British Columbia.
The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique
Soon JA, Meckley LM, Levine M, Marciante KD, Fielding DW, Ensom MH
PubMed: 18180535
2007

A Systematic Review of Limited Sampling Strategies for Platinum Agents Used in Cancer Chemotherapy
Clinical Pharmacokinetics
Gabriel W Loh, Lillian S L Ting, Mary H H Ensom
DOI: 10.2165/00003088-200746060-00002
2007

Efavirenz and Nevirapine in HIV-1 InfectionIs There a Role for Clinical Pharmacokinetic Monitoring?
Clinical Pharmacokinetics
Karen Dahri, Mary H H Ensom
DOI: 10.2165/00003088-200746020-00002
2007

Is C2 Monitoring or Another Limited Sampling Strategy Superior to C0 Monitoring in Improving Clinical Outcomes in Adult Liver Transplant Recipients?
Therapeutic Drug Monitoring
Judith Genevi??ve Marin, Marc Levine, Mary H. H Ensom
DOI: 10.1097/01.ftd.0000243965.97964.ca
10/2006

Pharmacokinetics of Mycophenolic Acid and Its Glucuronidated Metabolites in Stable Lung Transplant Recipients
Annals of Pharmacotherapy
Lillian SL Ting, Nilufar Partovi, Robert D Levy, K Wayne Riggs, Mary HH Ensom
DOI: 10.1345/aph.1h149
09/2006

Limited Sampling Strategy for Predicting Area Under the Concentration-Time Curve of Mycophenolic Acid in Adult Lung Transplant Recipients
Pharmacotherapy
Lillian S. L Ting, Nilufar Partovi, Robert D Levy, K. Wayne Riggs, Mary H. H Ensom
DOI: 10.1592/phco.26.9.1232
09/2006

Beyond Cyclosporine: A Systematic Review of Limited Sampling Strategies for Other Immunosuppressants
Therapeutic Drug Monitoring
Lillian S. L. Ting, Eric Villeneuve, Mary H. H. Ensom
DOI: 10.1097/01.ftd.0000211810.19935.44
06/2006

Pharmacokinetics of Intravenous Immunoglobulin: A Systematic Review
Pharmacotherapy
Tamar Koleba, Mary H. H Ensom
DOI: 10.1592/phco.26.6.813
06/2006

A Motivational Letter
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v59i2.221
04/2006

Stability of Nitrofurantoin in Extemporaneously Compounded Suspensions
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v59i1.460
02/2006

Outcomes of Bupropion Therapy for Smoking Cessation During Routine Clinical Use
Annals of Pharmacotherapy
Elan C Paluck, James P McCormack, Mary HH Ensom, Marc Levine, Judith A Soon, David W Fielding
DOI: 10.1345/aph.1g324
02/2006

A Critical Assessment of the Outcomes of Therapeutic Drug Monitoring
Pharmacokinetics and Pharmacodynamics: Principles of Therapeutic Drug Monitoring
2006

Special Pharmacokinetic Considerations in the Obese
Pharmacokinetics and Pharmacodynamics: Principles of Therapeutic Drug Monitoring
2006

Clinical Pharmacokinetics Service (Chinese edition)
China Medico-pharmaceutical Science & Technology Publishing House
2006

Dietary Influences on Drug Disposition
Pharmacokinetics and Pharmacodynamics: Principles of Therapeutic Drug Monitoring
2006

Limited sampling strategy for cyclosporine (Neoral®) area under the curve monitoring in pediatric kidney transplant recipients
Pediatric Transplantation
Dawn K. Strong, Amanda Lai, Dennis Primmett, Colin T. White, David S. Lirenman, James E. Carter, R. Morrison Hurley, Mumtaz Virji, Mary H.H. Ensom
DOI: 10.1111/j.1399-3046.2005.00339.x
10/2005

The Role of Therapeutic Monitoring of Everolimus in Solid Organ Transplantation
Therapeutic Drug Monitoring
Vincent H Mabasa, Mary H. H Ensom
DOI: 10.1097/01.ftd.0000175911.70172.2e
10/2005

Therapy with both magnesium sulfate and nifedipine does not increase the risk of serious magnesium-related maternal side effects in women with preeclampsia
American Journal of Obstetrics and Gynecology
Laura A. Magee, Saman Miremadi, Jing Li, Carol Cheng, Mary H.H. Ensom, Bruce Carleton, Anne-Marie Côté, Peter von Dadelszen
DOI: 10.1016/j.ajog.2004.11.059
07/2005

Clinical Pharmacokinetic Monitoring of Itraconazole Is Warranted in Only a Subset of Patients
Therapeutic Drug Monitoring
Susan S Buchkowsky, Nilufar Partovi, Mary H. H Ensom
DOI: 10.1097/01.ftd.0000150135.22645.ea
06/2005

UDP-glucuronosyltransferases and clinical drug-drug interactions
Pharmacology & Therapeutics
T KIANG, M ENSOM, T CHANG
DOI: 10.1016/j.pharmthera.2004.10.013
04/2005

A Prospective, Two-Phase Study of Intravenous Immunoglobulin (IVIG) in Hypogammaglobulinemia: Pharmacokinetic Characterization and a Dosing Sliding Scale
Canadian Journal of Hospital Pharmacy
04/2005

Effects of making emergency contraception available without a physician's prescription: a population-based study.
CMAJ : Canadian Medical Association Journal
Soon JA, Levine M, Osmond BL, Ensom MH, Fielding DW
DOI: 10.1503/cmaj.045019
PubMed: 15795408
03/2005

Stability of Thiamine in Extemporaneously Compounded Suspensions
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v58i1.284
02/2005

Utility of Anti-Xa Monitoring in Children Receiving Enoxaparin for Therapeutic Anticoagulation
The Journal of Pediatric Pharmacology and Therapeutics
Marianna Leung, Sharon H. Ho, Donald P. Hamilton, John K. Wu, David B. Dix, Louis D. Wadsworth, Mary H. H. Ensom
DOI: 10.5863/1551-6776-10.1.43
01/2005

Joys of Precepting: Lessons Learned
Canadian Journal of Hospital Pharmacy
2005

SirolimusThe Evidence for Clinical Pharmacokinetic Monitoring
Clinical Pharmacokinetics
Sunita Bond Stenton, Nilufar Partovi, Mary H H Ensom
DOI: 10.2165/00003088-200544080-00001
2005

Therapeutic Drug Monitoring of Ganciclovir in Bone Marrow Transplants
European Journal of Hospital Pharmacy
2005

Development and Implementation of a Hospital Pharmacy Journal Club: Experience at the Children’s & Women’s Health Centre of British Columbia
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v57i4.382
09/2004

Pharmacokinetics of Low Molecular Weight Heparin and Unfractionated Heparin in Pregnancy
Journal of the Society for Gynecologic Investigation
Mary H.H. Ensom, Mary D. Stephenson
DOI: 10.1016/j.jsgi.2004.02.007
09/2004

Treatment of antiphospholipid antibody syndrome (APS) in pregnancy: a randomized pilot trial comparing low molecular weight heparin to unfractionated heparin.
Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
Stephenson MD, Ballem PJ, Tsang P, Purkiss S, Ensworth S, Houlihan E, Ensom MH
DOI: 10.1016/s1701-2163(16)30644-2
PubMed: 15307977
08/2004

Provision of Emergency Contraceptives by PharmacistsBritish Columbia Experience a Template for other Provinces
CPJ
Judith A. Soon, Marc Levine, Brenda L. Osmond, Mary H. H. Ensom, David W. Fielding
DOI: 10.1177/171516350413700605
07/2004

Ganciclovir in Solid Organ Transplant RecipientsIs There a Role for Clinical Pharmacokinetic Monitoring?
Therapeutic Drug Monitoring
Julie Cates Scott, Nilufar Partovi, Mary H.H. Ensom
DOI: 10.1097/00007691-200402000-00014
02/2004

Estradiol in Severe Asthma with Premenstrual Worsening
Annals of Pharmacotherapy
Mary HH Ensom, Gina Chong, Bev Beaudin, Tony R Bai
DOI: 10.1345/aph.1d090
11/2003

Atovaquone–Proguanil for Prophylaxis and Treatment of Malaria
Annals of Pharmacotherapy
Fawziah Marra, James R Salzman, Mary HH Ensom
DOI: 10.1345/aph.1c473
09/2003

Estradiol in Premenstrual Asthma: A Double-Blind, Randomized, Placebo-Controlled, Crossover Study
Pharmacotherapy
Mary H. H. Ensom, Gina Chong, Danyi Zhou, Bev Beaudin, Stephen Shalansky, Tony R. Bai
DOI: 10.1592/phco.23.5.561.32201
05/2003

Mycophenolate Mofetil for Solid Organ Transplantation: Does the Evidence Support the Need for Clinical Pharmacokinetic Monitoring?
Therapeutic Drug Monitoring
Victoria C. Cox, Mary H. H. Ensom
DOI: 10.1097/00007691-200304000-00003
04/2003

Pharmacogenetics of the Proton Pump Inhibitors: A Systematic Review
Pharmacotherapy
Elaine Chong, Mary H. H. Ensom
DOI: 10.1592/phco.23.4.460.32128
04/2003

Drug Disposition and Therapy in Adolescence: The Effects of Puberty
The Journal of Pediatric Pharmacology and Therapeutics
Roxane R. Carr, Mary H.H. Ensom
DOI: 10.5863/1551-6776-8.2.86
04/2003

Mycophenolate Pharmacokinetics in Early Period Following Lung or Heart Transplantation
Annals of Pharmacotherapy
Mary HH Ensom, Nilufar Partovi, Diane Decarie, Andrew P Ignaszewski, Guy J Fradet, Robert D Levy
DOI: 10.1345/aph.1d099
2003

Stability of Hydrocortisone in Extemporaneously Prepared Oral Suspensions
Journal of Informed Pharmacotherapy
2003

Clinical Pharmacokinetics Specialty Practice
Encyclopedia of Clinical Pharmacy (Print)
Mary Ensom, Y Lam
DOI: 10.1201/b13789-33
11/2002

Research as an Avenue to Invigorate Your Practice?
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v55i4.599
09/2002

An update on the role of immunotherapy in reproductive failure
Immunology and Allergy Clinics of North America
Mary D Stephenson, Mary H.H Ensom
DOI: 10.1016/s0889-8561(02)00004-8
08/2002

Comment: unbound drug concentration versus unbound drug fraction
The Annals of Pharmacotherapy
Mary HH Ensom
DOI: 10.1345/1542-6270(2002)0362.0.co;2
04/2002

Pharmacokinetics and Protein Binding of Mycophenolic Acid in Stable Lung Transplant Recipients
Therapeutic Drug Monitoring
Mary H. H. Ensom, Nilufar Partovi, Diane Decarie, Randall J. Dumont, Guy Fradet, Robert D. Levy
DOI: 10.1097/00007691-200204000-00013
04/2002

Fluoxetine in the treatment of premenstrual dysphoric disorder.
The Annals of pharmacotherapy
Carr RR, Ensom MH
DOI: 10.1345/aph.1a265
PubMed: 11918525
04/2002

Role of Fomepizole in the Management of Ethylene Glycol Toxicity
Pharmacotherapy
Deon P. Druteika, Peter J. Zed, Mary H. H. Ensom
DOI: 10.1592/phco.22.5.365.33187
03/2002

Effect of Pregnancy on Bone Mineral Density in Healthy Women
Obstetrical and Gynecological Survey
Mary H. H. Ensom, Pamela Y. Liu, Mary D. Stephenson
DOI: 10.1097/00006254-200202000-00022
02/2002

Stability of Mycophenolate Mofetil in a 1:1 Mixture of Ora-Sweet and Ora-Plus
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v55i1.547
02/2002

Amphotericin B Disposition After Aerosol Inhalation in Lung Transplant Recipients
The Annals of Pharmacotherapy
Fawziah Marra, Nilufar Partovi, Kishor M Wasan, Evan H Kwong, Mary HH Ensom, Shawn M Cassidy, Guy Fradet, Robert D Levy
DOI: 10.1345/1542-6270(2002)0362.0.co;2
01/2002

IVIG Pharmacokinetics
IVIG Utilization Management Handbook
2002

Stability of Domperidone in Extemporaneously Compounded Suspensions
Journal of Informed Pharmacotherapy
2002

Pharmacokinetic Pearls for the Clinical Pharmacist
Journal of Informed Pharmacotherapy
2002

The Developing Role of Pharmacists in Patient Access to Emergency Contraception
Disease Management & Health Outcomes
Judith A. Soon, Marc Levine, Mary H.H. Ensom, Jacqueline S. Gardner, Hilary M. Edmondson, David W. Fielding
DOI: 10.2165/00115677-200210100-00001
2002

The Role of Immunotherapy in Reproductive Failure
Infertility and Reproductive Medicine Clinics of North America
2002

Pharmacokinetics of Fluconazole in Trauma Patients with Postpyloric Feeding Tubes
Annals of Pharmacotherapy
George A Davis, Robert P Rapp, Paul A Kearney, Mary HH Ensom
DOI: 10.1345/aph.1a055
11/2001

Evaluation of droperidol in the acutely agitated child or adolescent.
Canadian journal of psychiatry. Revue canadienne de psychiatrie
Hameer O, Collin K, Ensom MH, Lomax S
PubMed: 11761643
11/2001

A limited sampling strategy for cyclosporine area under the curve monitoring in lung transplant recipients
The Journal of Heart and Lung Transplantation
Randall J Dumont, Nilufar Partovi, Robert D Levy, Guy Fradet, Mary H.H Ensom
DOI: 10.1016/s1053-2498(01)00272-8
08/2001

Role of Therapeutic Drug Monitoring for Protease Inhibitors
Annals of Pharmacotherapy
Leela John, Fawziah Marra, Mary HH Ensom
DOI: 10.1345/aph.10249
06/2001

A Study of the Pharmacokinetic Profile of Low-Dose Hepatitis B Immune Globulin in Long-Term Liver Transplant Recipients for Chronic Hepatitis B Infection
American Journal of Transplantation
Nilufar Partovi, Michelle W. Guy, Mary H. H. Ensom, Michael A. Noble, Eric M. Yoshida
DOI: 10.1034/j.1600-6143.2001.010110.x
05/2001

2001: A Pharmacogenomics Odyssey
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v54i1.610
04/2001

Post Hoc Power Analysis: An Idea Whose Time Has Passed?
Pharmacotherapy: Official Journal of the American College of Clinical Pharmacy
Marc Levine, Mary H. H. Ensom
DOI: 10.1592/phco.21.5.405.34503
04/2001

Stability of Dexamethasone in Extemporaneously Compounded Oral Suspensions
Canadian Journal of Hospital Pharmacy
2001

PharmacogeneticsThe Therapeutic Drug Monitoring of the Future?
Clinical Pharmacokinetics
Mary H.H. Ensom, Thomas K.H. Chang, Payal Patel
DOI: 10.2165/00003088-200140110-00001
2001

Comment: publication rates of abstracts.
The Annals of pharmacotherapy
Ensom MH, Walker SE
DOI: 10.1345/aph.19375a
PubMed: 11144712
12/2000

The Authors' Reply
Clinical Pharmacokinetics
Randall J. Dumont and Mary H.H. Ensom
DOI: 10.2165/00003088-200039040-00007
10/2000

Phenytoin and Enteral Feedings: Does Evidence Support an Interaction?
Annals of Pharmacotherapy
Sam CS Au Yeung, Mary HH Ensom
DOI: 10.1345/aph.19355
07/2000

Methods for Clinical Monitoring of Cyclosporin in Transplant Patients
Clinical Pharmacokinetics
Randall J. Dumont, Mary H. Ensom
DOI: 10.2165/00003088-200038050-00004
05/2000

Gender-Based Differences and Menstrual Cycle-Related Changes in Specific Diseases: Implications for Pharmacotherapy
Pharmacotherapy
Mary H. H. Ensom
DOI: 10.1592/phco.20.6.523.35161
05/2000

Pharmacokinetic Drug Interactions Between Oral Contraceptives and Second-Generation Anticonvulsants
Clinical Pharmacokinetics
Kerry Wilbur, Mary H.H. Ensom
DOI: 10.2165/00003088-200038040-00004
04/2000

The Emerging Use of Low-Molecular-Weight Heparins in Pregnancy
Journal SOGC
Mary D. Stephenson, Mary H.H. Ensom
DOI: 10.1016/s0849-5831(16)31417-3
02/2000

Getting Further Information from Poster Presentations
American Journal of Health-System Pharmacy
01/2000

Peak Expiratory Flow Rate and Premenstrual Symptoms in Healthy Nonasthmatic Women
Pharmacotherapy
Elaine Chong, Mary H. H. Ensom
DOI: 10.1592/phco.20.19.1409.34857
2000

Vancomycin Overdose in a 6-Month Old Female
Canadian Journal of Hospital Pharmacy
DOI: 10.4212/cjhp.v53i1.692
2000

Stability of Aminophylline in Extemporaneously Compounded Oral Suspensions
Journal of Informed Pharmacotherapy
2000

Allergies. A Motherhood IssueNon-Refereed
Pharmacy Practice
2000

Low-Molecular-Weight Heparins in Pregnancy
Pharmacotherapy
Mary H. H. Ensom, Mary D. Stephenson
DOI: 10.1592/phco.19.13.1013.31588
09/1999

Premenstrual Symptoms in Women with Premenstrual Asthma
Pharmacotherapy
Mary H. H. Ensom, Elaine Chong, Diana Carter
DOI: 10.1592/phco.19.6.374.31050
04/1999

Evaluation of Vomiting and Antiemetic Use in Postoperative Pediatric Patients
Journal of Pediatric Pharmacy Practice
1999

A Pilot Study of Estrogen’s Effects on Bronchial Myocyte Adhesion Molecule Expression
Pharmacotherapy
George R. Dickens, Christopher J. Matheny, Peter E. Morris, G. Dennis Clifton, Mary H. H. Ensom
DOI: 10.1592/phco.19.18.1426.30902
1999

Thanksgiving Reflections on Being an Institutional Pharmacy Practitioner
Canadian Journal of Hospital Pharmacy
1999

Authors' Reply
Annals of Pharmacotherapy
Mary HH Ensom, George A Davis, Deanna L Finnell
DOI: 10.1177/106002809803201001
10/1998

Validation of the Hartford Nomogram in Trauma Surgery Patients
Annals of Pharmacotherapy
Deanna L Finnell, George A Davis, Cheryl D Cropp, Mary HH Ensom
DOI: 10.1345/aph.17243
04/1998

Collaboration between Pharmacy and Laboratory: Defining Total Allowable Error Limits for Therapeutically Monitored Drugs
Annals of Pharmacotherapy
Kristine M Radomski, Barbara A Bush, Mary HH Ensom
DOI: 10.1345/aph.17187
02/1998

Evaluation of Aminoglycoside Pharmacokinetics in Postpartum Patients Using Bayesian Forecasting
Therapeutic Drug Monitoring
Cheryl D. Cropp, George A. Davis, Mary H. H. Ensom
DOI: 10.1097/00007691-199802000-00013
02/1998

Clinical Pharmacokinetics in the 21st CenturyDoes the Evidence Support Definitive Outcomes?
Clinical Pharmacokinetics
H Ensom, George A. Davis, Cheryl D. Cropp, Robin J. Ensom
DOI: 10.2165/00003088-199834040-00001
1998

Alpha1-acid glycoprotein concentrations and cerebrospinal fluid drug distribution after subarachnoid hemorrhage.
Pharmacotherapy
Woodward DK, Hatton J, Ensom MH, Young B, Dempsey R, Clifton GD
PubMed: 9758316
1998

Candles Under Bushels: Unpublished Abstracts
Canadian Journal of Hospital Pharmacy
1998

From Abstract to Publication: What Helps Make the Grade?
Canadian Journal of Hospital Pharmacy
1998

ASHP Statement on the Pharmacist’s Role in Clinical Pharmacokinetic Monitoring
American Journal of Health-System Pharmacy
1998

General versus subpopulation values in Bayesian prediction of aminoglycoside pharmacokinetics in hematology-oncology patients.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Radomski KM, Davis GA, Chandler MH
PubMed: 9066862
03/1997

Assay Interaction between Oxaprozin and Phenytoin
Annals of Pharmacotherapy
Tejal Patel, Kristine M Radomski, Mary Hh Chandler
DOI: 10.1177/106002809703100224
02/1997

T lymphocyte beta 2-adrenergic receptor function and density after acute myocardial infarction.
Pharmacotherapy
McCoy RA, Clifton GD, Booth DC, Bartels LA, Chandler MH
PubMed: 9085329
1997

Premenstrual asthma: the effect of estrogen on symptoms, pulmonary function, and beta 2-receptors.
Pharmacotherapy
Chandler MH, Schuldheisz S, Phillips BA, Muse KN
PubMed: 9085312
1997

Integrating Pharmacokinetics into Point-of-Care Information Systems
Clinical Pharmacokinetics
W. Greg Leader, Stanley L. Pestotnik, Mary H.H. Chandler
DOI: 10.2165/00003088-199631030-00001
09/1996

Comparison of creatinine clearance estimation methods in patients with trauma.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Davis GA, Chandler MH
PubMed: 8744465
05/1996

Surgical Care of the Elderly: Drug Therapy and Drug Interactions
Oral and Maxillofacial Surgery Clinics of North America
1996

Dirithromycin increases ethinyl estradiol clearance without allowing ovulation.
Obstetrics and gynecology
Wermeling DP, Chandler MH, Sides GD, Collins D, Muse KN
DOI: 10.1016/0029-7844(95)00075-3
PubMed: 7784027
07/1995

Pharmacokinetic Optimisation of Vancomycin Therapy
Clinical Pharmacokinetics
W. Greg Leader, Mary H.H. Chandler, Mary Castiglia
DOI: 10.2165/00003088-199528040-00005
04/1995

Therapeutic Drugs
Clinical Guide to Laboratory Tests
1995

Constructive versus Destructive Criticism
American Journal of Health-System Pharmacy
1995

A simplified high-performance liquid chromatographic method for direct determination of warfarin enantiomers and their protein binding in stroke patients.
Therapeutic drug monitoring
Cai WM, Hatton J, Pettigrew LC, Dempsey RJ, Chandler MH
PubMed: 7846751
10/1994

Creatinine-clearance estimates for predicting gentamicin pharmacokinetic values in obese patients.
American journal of hospital pharmacy
Leader WG, Tsubaki T, Chandler MH
PubMed: 7985687
09/1994

Pharmacokinetics of anti-infective agents in paediatric patients.
Clinical pharmacokinetics
Butler DR, Kuhn RJ, Chandler MH
DOI: 10.2165/00003088-199426050-00005
PubMed: 8055682
05/1994

Symptomatology, Pulmonary Function and Response, and TLymphocyte ß2-Receptors During Smoking Cessation in Patients with Chronic Obstructive Pulmonary Disease
Pharmacotherapy
PubMed: 8197034
04/1994

Clinical pharmacy practice in urban China.
American journal of hospital pharmacy
Cai WM, Tan HS, Ling SS, Chandler MH
PubMed: 8203393
03/1994

Health care and institutional pharmacy practice in Japan.
American journal of hospital pharmacy
Tsubaki T, Iga T, Chandler MH
PubMed: 8017427
02/1994

Evaluating new and traditional methods for aminoglycoside dosing in patients with various degrees of renal function.
Pharmacotherapy
Tsubaki T, Chandler MH
PubMed: 7937274
1994

Effects of long-term oral carvedilol on the steady-state pharmacokinetics of oral digoxin in patients with mild to moderate hypertension.
Pharmacotherapy
Wermeling DP, Field CJ, Smith DA, Chandler MH, Clifton GD, Boyle DA
PubMed: 7997394
1994

Development of a Clinical Pharmacology Graduate Program at the University of Kentucky
American Journal of Pharmaceutical Education
1994

Clinical Pharmacokinetics Services in the United States
Chinese Pharmaceutical Journal
1994

Modified Michaelis-Menten equation for estimating unbound-phenytoin concentrations.
Clinical pharmacy
Rhoney DH, Leader WG, Chandler MH
PubMed: 8137609
12/1993

Predicting vancomycin pharmacokinetics by using aminoglycoside pharmacokinetics.
Clinical pharmacy
Welch LP, Leader WG, Chandler MH
PubMed: 8137608
12/1993

Influence of Serum Separator Tubes on Total and Free Phenytoin Concentrations and Dosages
Therapeutic Drug Monitoring
Wei M. Cai, W. Greg Leader, William H. Porter, Mary H. H. Chandler
DOI: 10.1097/00007691-199310000-00011
10/1993

Computers in PharmacokineticsChoosing Software for Clinical Decision Making
Clinical Pharmacokinetics
Daniel E. Buffington, Victor Lampasona, Mary H.H. Chandler
DOI: 10.2165/00003088-199325030-00004
09/1993

Estimation of creatinine clearance in patients with gynecologic cancer.
Clinical pharmacy
Tsubaki T, Goodin S, Leader WG, Chandler MH
PubMed: 8306567
09/1993

Preventing Theophylline Dosing Errors from Conversion of Dyphylline
Annals of Pharmacotherapy
William K. Fleming, Annie M. Herrington, Mary H.H. Chandler
DOI: 10.1177/106002809302700625
06/1993

The Bayesian Approach to Pharmacokinetic ForecastingNon-Refereed
AACC TDM & Toxicology
1993

Pharmacokinetics of ondansetron in patients receiving cisplatin therapy.
Clinical pharmacy
Parr MD, McIntyre WJ, Henderson LM, MacDonald JS, Chandler MH
PubMed: 1286552
12/1992

Multiple Dose Pharmacokinetics of Four Different Doses of Nisoldipine in Hypertensive Patients
The Journal of Clinical Pharmacology
Mary H. H. Chandler, G. Dennis Clifton, John T. Lettieri, Arthur L. Mazzu, Douglas R. Allington, Andrew C. Thieneman, Thomas S. Foster, Michael R. Harrison
DOI: 10.1177/009127009203200614
06/1992

Differential response of beta-adrenergic receptor-mediated heart rate and aortic blood flow acceleration to timolol.
Clinical pharmacology and therapeutics
Clifton GD, Chandler MH, Pennell AT, McCoy RA, Harrison MR
DOI: 10.1038/clpt.1992.25
PubMed: 1312003
03/1992

Dietary Influences on Drug Disposition
Applied Pharmacokinetics: Principles of Therapeutic Drug Monitoring
1992

Sources of Self-treatment Information and Use of Home Remedies and Over-the-Counter Medications Among Older Adults
Journal of Geriatric Drug Therapy
1992

Special Pharmacokinetic Considerations in the Obese
Applied Pharmacokinetics: Principles of Therapeutic Drug Monitoring
1992

In vivo and in vitro beta 2-adrenergic receptor responsiveness in young and elderly asthmatics.
Pharmacotherapy
Hamelin BA, Blouin RA, Wolf KM, Clifton GD, Chandler MH
PubMed: 1331993
1992

Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin.
British journal of clinical pharmacology
Smith DA, Chandler MH, Shedlofsky SI, Wedlund PJ, Blouin RA
PubMed: 1768567
12/1991

Effect of ceftazidime, cefotaxime, and cefoperazone on serum tobramycin concentrations.
American journal of hospital pharmacy
Pennell AT, Allington DR, Chandler MH
PubMed: 2029001
03/1991

Evaluation of precision and accuracy of a fluorescence polarization immunoassay system after dilution of serum samples containing fluorescein dye.
Therapeutic drug monitoring
Toler SM, Porter WH, Chandler MH
PubMed: 2349618
05/1990

Pulmonary Function in the Elderly: Response to Theophylline Bronchodilation
The Journal of Clinical Pharmacology
Mary H. H. Chandler, G. Dennis Clifton, Nausherwan K. Burki, Bernard A. Hunt, Robert A. Blouin
DOI: 10.1002/j.1552-4604.1990.tb03602.x
04/1990

Multiple-dose pharmacokinetics of concurrent oral ciprofloxacin and rifampin therapy in elderly patients.
Antimicrobial agents and chemotherapy
Chandler MH, Toler SM, Rapp RP, Muder RR, Korvick JA
DOI: 10.1128/aac.34.3.442
PubMed: 2185691
03/1990

Short Communication; Using Clinical Data to Determine Vancomycin Dosing Parameters
Therapeutic Drug Monitoring
Julie K. Birt, Mary H. H. Chandler
DOI: 10.1097/00007691-199003000-00017
03/1990

Drug interactions in older adults.
The Journal of the Kentucky Medical Association
Coons SJ, Chandler MH
PubMed: 2313168
03/1990

Therapeutic Drugs
Clinical Guide to Laboratory Tests
1990

Severe phenytoin intoxication as a result of altered protein binding in AIDS.
DICP : the annals of pharmacotherapy
Toler SM, Wilkerson MA, Porter WH, Smith AJ, Chandler MH
DOI: 10.1177/106002809002400708
PubMed: 2375139
1990

Home monitoring of theophylline levels: a novel therapeutic approach.
Pharmacotherapy
Chandler MH, Clifton GD, Louis BA, Coons SJ, Foster TS, Phillips BA
PubMed: 2388876
1990

Effect of fluorescein concentration on gentamicin immunoassay results.
Clinical pharmacy
Wilkerson MA, Toler SM, Goldsmith TL, Porter WH, Strodel WE, Chandler MH
PubMed: 2689061
12/1989

Use of an aminoglycoside-monitoring form to improve communication among nurses, phlebotomists, and pharmacists.
American journal of hospital pharmacy
Chandler MH, Stevenson LM, Parr MD
PubMed: 2603886
12/1989

Free and total serum digoxin concentrations in a renal failure patient after treatment with digoxin immune Fab.
Clinical pharmacy
Clifton GD, McIntyre WJ, Zannikos PN, Harrison MR, Chandler MH
PubMed: 2743737
06/1989

Utility of Rapid Theophylline Assay in Clinical Research
Therapeutic Drug Monitoring
Mary H. H. Chandler, Jeffrey A. Hughes, G. Dennis Clifton
DOI: 10.1097/00007691-198905000-00024
05/1989

Stereoselective binding of propranolol in the elderly.
British Journal of Clinical Pharmacology
P. Colangelo, M. Chandler, R. Blouin, P. McNamara
DOI: 10.1111/j.1365-2125.1989.tb05402.x
04/1989

Teaching Interview Techniques Utilizing an Instructional Videotape
Educational Gerontology
Mary H.H. Chandler
DOI: 10.1080/0380127890150405
01/1989

A Clinical Comparison of Two Methods for Calculating Aminoglycoside Volume of Distribution
Clinical Pharmacy
1989

The effects of renal function on the disposition of isradipine.
Journal of clinical pharmacology
Chandler MH, Schran HF, Cutler RE, Smith AJ, Gonasun LM, Blouin RA
DOI: 10.1002/j.1552-4604.1988.tb05717.x
PubMed: 2977394
12/1988

Age-associated stereoselective alterations in hexobarbital metabolism.
Clinical pharmacology and therapeutics
Chandler MH, Scott SR, Blouin RA
DOI: 10.1038/clpt.1988.55
PubMed: 3356087
04/1988

Theophylline Pharmacokinetics in the Elderly
Geriatric Drug Therapy
1988

Simultaneous quantitation of d- and l-hexobarbital in rat blood by high-performance liquid chromatography
Journal of Chromatography B: Biomedical Sciences and Applications
Mary H. Huang Chandler, Robert J. Guttendorf, Robert A. Blouin, Peter J. Wedlund
DOI: 10.1016/0378-4347(87)80311-0
01/1987

Research

Pharmacokinetics and Pharmacogenetics of Mycophenolate in Islet Cell Transplant Recipients
This project seeks to characterize the pharmacokinetics and pharmacogenetics of mycophenolic acid (MPA) and its glucuronidated metabolites and develop limited sampling strategies for this patient subpopulation.

Pharmacogenetics of Mycophenolate in Thoracic Transplant Recipients: Role of UDP-Glucuronosyltransferases
This study seeks to determine if the inter-patient variability observed in the mycophenolate pharmacokinetics of thoracic transplant recipients can be partially explained by genetic variability in the UDP-glucuronosyltransferase (UGT) enzymes responsible for its metabolism.

Pharmacokinetics and Pharmacodynamics of Intravenous Immunoglobulin (IVIG) Prior to and During Pregnancy in Patients with Unexplained Secondary Recurrent Spontaneous Abortion (RSA)
This is the first study ever to evaluate the pharmacokinetics (study of what the body does to a drug) and pharmacodynamics (study of what drugs do to a body) prior to and during pregnancy in patients of intravenous immunoglobulin with recurrent pregnancy loss.

Honours & Awards

Distinguished Service Award, B.C. Branch Canadian Society of Hospital Pharmacists (C.S.H.P.), given to an individual "who has shown significant and extensive contribution to hospital pharmacy at the local, provincial, and national levels" (2014)

Class of 2014 Master Teacher Award, Faculty of Pharmaceutical Sciences, UBC (2014)

Inaugural Class (n=4) of Hall of Distinguished Alumni, University of Kentucky College of Pharmacy (2015)