Brief Resolved Unexplained Events (BRUEs): Along with an international collaboration, I am completing a project to identify infants with a serious diagnosis among those presenting with a BRUE. The derived algorithm will be implemented in a multicenter quality improvement project across North America.
Urinary Tract Infections (UTIs): Our team has recently completed a systematic review on the effective duration of treatment for neonates with urinary tract infections. I am currently collaborating locally with members of the Division of General Pediatrics and Infectious Disease to shorten the length of hospital stay and treatment duration for these patients as a quality improvement.
Crowdsourcing Systematic Reviews: Using an innovative crowdsourcing approach, our team has been able to accelerate the process of evidence synthesis, leading to the completion of systematic reviews within a short period of time. To date, we have completed several systematic reviews targeting the treatment of UTIs, the treatment of pneumonia, the role of high-dose vitamin D, and a database of all available pediatric cardiac RCTs. As an example, we completed the systematic review on UTI treatment with a crowd from 13 different countries, and spanning 5 different continents. The crowd was able to screen more than 10,000 publications within 2-3 weeks.