Researchers have discovered mutations in a gene called NOTCH1 that causes Adams-Oliver syndrome (AOS), a rare and potentially fatal genetic disorder.

An important discovery about how our gut protects our bodies from dangerous infections may help scientists understand the causes of inflammatory bowel disease, a group of common disorders that cause painful abdominal cramps, diarrhea, vomiting and other debilitating symptoms.

New research from CFRI and BC Injury Research & Prevention Unit (BCIRPU) shows that helmet laws really do make a difference.

Dr. James Lim's laboratory at the Child & Family Research Institute focuses on finding new ways to help children fight leukemia. Dr. Lim's team recently discovered that a group of cell adhesion proteins called integrins, which promote the ability of leukemia cells to survive chemotherapy. 

For one family, a young girl’s diagnosis with a rare genetic disease ended years of tests and referrals to explain her puzzling symptoms: an overgrowth of fatty tissue on specific parts of her body including her belly and one leg.

Hypertensive disorders of pregnancy (HDPs), including life-threatening conditions like preeclampsia and HELLP syndrome, affect thousands of women in Canada every year and can cause grave complications like maternal stroke, preterm delivery and stillbirth.

Dr. Aubrey Tingle, founding Executive Director of CFRI and Professor Emeritus, Department of Pediatrics at the University of British Columbia, has been named to the Order of British Columbia.

New research from CFRI, BC Children’s Hospital, and paediatric rheumatology centres across Canada shows that modern treatments for juvenile idiopathic arthritis (JIA) are highly effective.

“It’s really encouraging to talk to girls, and to hear their enthusiasm about helping and participating in health research,” says Shadi Mahmoodi, Vaccine Evaluation Center (VEC) Research Assistant and recruiter for the QUEST HPV Study.

Scientists at the Centre for Molecular Medicine and Therapeutics and the Child and Family Research Institute have uncovered a new cellular trigger for a stress response that plays an important role in causing diabetes.

New research from CFRI and the Catalan Institute of Oncology in Spain sheds light on the cellular processes that underpin a disease that can cause developmental delay in children.

Takuro (Tak) Ishikawa, a UBC PhD student at CFRI, recently completed a systematic review of evidence presented in studies on child passenger safety in B.C. Aboriginal communities.

The painful, life-saving procedures that premature babies often undergo in their first few months of life are associated with altered brain development and lower IQ scores at seven years of age, a new study has found. The findings were published in the March 2014 issue of Pediatrics.

Congratulations to Dr. Elizabeth M. Simpson on receiving the 2014 Genome British Columbia Award for Scientific Excellence.

A Vancouver-led research initiative to prevent deaths of moms and babies got a boost recently with a new $1.5-million grant from the Bill & Melinda Gates Foundation. The grant will expand efforts to improve diagnosis and care for pregnant women with pre-eclampsia.

 

New research shows sugary drinks are the worst offenders in the fight against youth obesity and recommends that B.C. schools fully implement healthy eating guidelines to reduce their consumption.

A team of researchers at CFRI, CMMT, BC Children’s, and UBC have uncovered a genetic cause of excess ammonia in the blood of newborns, increasing the chances that children can be treated before suffering permanent brain damage.

A team of researchers at Centre for Molecular Medicine and Therapeutics (CMMT) and CFRI, led by Dr. Blair Leavitt, recently described a promising approach that alleviates the symptoms of ALS in mice, according to new data published in the scientific journal Nature Communications.

A clinical tool to aid in diagnosing 81 rare inborn errors of metabolism that are potentially treatable is now being by used by an average of 1200 clinicians and scientists every month. 

Dr. Ran Goldman reviews current research to provide evidence-based responses to physician questions in his column in Canadian Family Physician, the official journal of The College of Family Physicians of Canada. This month, Dr. Goldman and pediatric resident Dr. Adela Matejcek address a question about a routine delivery room procedure.