Peter C.K. Leung

Advances in human oocyte in vitro maturation: current status and future perspectives: a narrative review

Reproduction and Fertility

Meiju Liu and Jie Cui and Hsun-Ming Chang and Jing Liu and Peter C K Leung

10 / 2025

Enhanced maturation of mouse immature oocytes using a novel three-dimensional culture system

Theriogenology

Zhao, X. and Zhang, X. and Wu, S. and Zhang, S. and Chang, H.-M. and Leung, P.C.K. and Tan, J.

Correction: Loss of CDYL results in suppression of CTNNB1 and decreased endometrial receptivity(Front. Cell Dev. Biol., (2020), 8, (105), 10.3389/fcell.2020.00105)

Frontiers in Cell and Developmental Biology

Zhou, X. and Xu, B. and Zhang, D. and Jiang, X. and Chang, H.-M. and Leung, P.C.K. and Xia, X. and Zhang, A.

RNA modifications in female reproductive physiology and disease: Emerging roles and clinical implications

Human Reproduction Update

Xiang, Y. and Chang, H.-M. and Leung, P.C.K. and Bai, L. and Zhu, Y.

Roles of bone morphogenetic proteins in endometrial remodeling during the human menstrual cycle and pregnancy

Human Reproduction Update

Wei, D. and Su, Y. and Leung, P.C.K. and Li, Y. and Chen, Z.-J.

Bone morphogenetic protein 6 induces downregulation of pentraxin 3 expression in human granulosa lutein cells in women with polycystic ovary syndrome

Journal of Assisted Reproduction and Genetics

Xin, X. and Chang, H.-M. and Leung, P.C.K. and Dong, L. and Li, J. and Lian, F. and Wu, H.

EGF-like growth factors upregulate pentraxin 3 expression in human granulosa-lutein cells

Journal of Ovarian Research

Li, Y. and Chang, H.-M. and Zhu, H. and Sun, Y.-P. and Leung, P.C.K.

Single-cell assessment of primary and stem cell-derived human trophoblast organoids as placenta-modeling platforms

Developmental Cell

Shannon, M.J. and McNeill, G.L. and Koksal, B. and Baltayeva, J. and Wchter, J. and Castellana, B. and Peaherrera, M.S. and Robinson, W.P. and Leung, P.C.K. and Beristain, A.G.

Bone Morphogenetic Protein 6 Induces Downregulation of Pentraxin 3 Expression in Human Granulosa Cells through the SMAD-Dependent Signaling Pathway in Women with Polycystic Ovary Syndrome

Research Square

Xin, X. and Chang, H.-M. and Leung, P.C.K. and Dong, L. and Li, J. and Lian, F. and Wu, H.

ID3 mediates BMP2-induced downregulation of ICAM1 expression in human endometiral stromal cells and decidual cells

Frontiers in Cell and Developmental Biology

Luo, J. and Wang, Y. and Chang, H.-M. and Zhu, H. and Yang, J. and Leung, P.C.K.

Collagen-based biomaterials in organoid technology for reproductive medicine: composition, characteristics, and applications

Collagen and leather

Feng, B. and Yang, H. and Zhu, M. and Li, J. and Chang, H.-M. and Leung, P.C.K. and Guo, J. and Zhang, Y.

Growth differentiation factor myostatin regulates epithelial-mesenchymal transition genes and enhances invasion by increasing serine protease inhibitors E1 and E2 in human trophoblast cells

FASEB Journal

AbdelHafez, F.F. and Klausen, C. and Zhu, H. and Yi, Y. and Leung, P.C.K.

ANGPTL4 inhibits granulosa cell proliferation in polycystic ovary syndrome by EGFR/JAK1/STAT3-mediated induction of p21

FASEB Journal

Jiang, Q. and Miao, R. and Wang, Y. and Wang, W. and Zhao, D. and Niu, Y. and Ding, Q. and Li, Y. and Leung, P.C.K. and Wei, D. and Chen, Z.-J.

A Novel Three-Dimensional Follicle Culture System Decreases Oxidative Stress and Promotes the Prolonged Culture of Human Granulosa Cells

ACS Applied Materials and Interfaces

Zhao, X. and Zhang, S. and Gao, S. and Chang, H.-M. and Leung, P.C.K. and Tan, J.

Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia

Journal of Translational Medicine

Liu, M. and Niu, Y. and Ma, K. and Leung, P.C.K. and Chen, Z.-J. and Wei, D. and Li, Y.

Editorial: Polycystic ovary syndrome: mechanism and management"volume II

Frontiers in Endocrinology

Wang, Y. and Leung, P. and Li, R. and Wu, Y. and Huang, H.

Betacellulin regulates gap junction intercellular communication by inducing the phosphorylation of connexin 43 in human granulosa-lutein cells

Research Square

Li, Y. and Chang, H.-M. and Sung, Y.-W. and Zhu, H. and Leung, P.C.K. and Sun, Y.-P.

NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling

Experimental Cell Research

Wu, Z. and Jia, Q. and Liu, B. and Fang, L. and Leung, P.C.K. and Cheng, J.-C.

BMP2 suppresses the production of pentraxin 3 in human endometrial stromal and decidual stromal cells

The FASEB Journal

Yu Zhang and Hsun-Ming Chang and Hua Zhu and Peter C. K. Leung

05 / 2022

Myostatin increases human trophoblast cell invasion by upregulating N-cadherin via SMAD2/3-SMAD4 signaling

Biology of Reproduction

Abdelhafez, F. and Klausen, C. and Zhu, H. and Leung, P.C.K.

Single-cell assessment of trophoblast stem cell-based organoids as human placenta-modeling platforms

bioRxiv

Shannon, M.J. and McNeill, G.L. and Koksal, B. and Baltayeva, J. and Wchter, J. and Castellana, B. and Peaherrera, M.S. and Robinson, W.P. and Leung, P.C.K. and Beristain, A.G.

Expression of long noncoding RNAs in the ovarian granulosa cells of women with diminished ovarian reserve using high-throughput sequencing

Research Square

Dong, L. and Xin, X. and Chang, H.-M. and Leung, P.C.K. and Yu, C. and Lian, F. and Wu, H.

Impact of growth hormone-releasing hormone antagonist on decidual stromal cell growth and apoptosis in vitro

Biology of Reproduction

Wu, H.-M. and Chen, L.-H. and Schally, A.V. and Huang, H.-Y. and Soong, Y.-K. and Leung, P.C.K. and Wang, H.-S.

Editorial: Polycystic ovary syndrome (PCOS): Mechanism and management

Frontiers in Endocrinology

Wang, Y. and Leung, P. and Li, R. and Wu, Y. and Huang, H.

Characterization of the roles of amphiregulin and transforming growth factor 1 in microvasculature-like formation in human granulosa-lutein cells

Frontiers in Cell and Developmental Biology

Li, H. and Chang, H.-M. and Li, S. and Klausen, C. and Shi, Z. and Leung, P.C.K.

Activin A promotes hyaluronan production and upregulates versican expression in human granulosa cells

Biology of Reproduction

Tian, S. and Zhang, H. and Chang, H.-M. and Klausen, C. and Huang, H.-F. and Jin, M. and Leung, P.C.K.

The interleukin-6 trans-signaling promotes progesterone production in human granulosa-lutein cells

Biology of Reproduction

Li, S.-J. and Chang, H.-M. and Wang, J.H. and Yang, J. and Leung, P.C.K.

Primary specification of blastocyst trophectoderm by scRNA-seq: New insights into embryo implantation

Science Advances

Liu, D. and Chen, Y. and Ren, Y. and Yuan, P. and Wang, N. and Liu, Q. and Yang, C. and Yan, Z. and Yang, M. and Wang, J. and Lian, Y. and Yan, J. and Zhai, F. and Nie, Y. and Zhu, X. and Chen, Y. and Li, R. and Chang, H.-M. and Leung, P.C.K. and Qiao, J. and Yan, L.

Transcription factor SOX4 facilitates BMP2-regulated gene expression during invasive trophoblast differentiation

The FASEB Journal

Yuyin Yi and Hua Zhu and Christian Klausen and Peter C. K. Leung

12 / 2021

Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells

Reproductive Biology and Endocrinology

Xiaoyan Luo and Hsun-Ming Chang and Yuyin Yi and Yingpu Sun and Peter C. K. Leung

11 / 2021

BMP6 increases CD68 expression by up-regulating CTGF expression in human granulosa-lutein cells

Molecular and Cellular Endocrinology

Xin-Yue Zhang and Hsun-Ming Chang and Yuyin Yi and Hua Zhu and Rui-Zhi Liu and Peter C.K. Leung

10 / 2021

Bone morphogenetic protein 2 upregulates SERPINE2 expression through noncanonical SMAD2/3 and p38 MAPK signaling pathways in human granulosa-lutein cells

The FASEB Journal

Xiaoyan Luo and Hsun-Ming Chang and Yuyin Yi and Peter C. K. Leung and Yingpu Sun

09 / 2021

Outcomes comparison of IVF/ICSI among different trigger methods for final oocyte maturation: A systematic review and meta-analysis

The FASEB Journal

Yu Zhang and Xiaoyan Guo and Linjiang Guo and Hsun-Ming Chang and Jing Shu and Peter C. K. Leung

07 / 2021

lncRNA DDGC participates in premature ovarian insufficiency through regulating RAD51 and WT1

Molecular Therapy - Nucleic Acids

Li, D. and Xu, W. and Wang, X. and Dang, Y. and Xu, L. and Lu, G. and Chan, W.-Y. and Leung, P.C.K. and Zhao, S. and Qin, Y.

Recent progress in the treatment of women with diminished ovarian reserve

Gynecology and Obstetrics Clinical Medicine

Yin, J. and Chang, H.-M. and Li, R. and Leung, P.C.K.

Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion Molecules

Frontiers in Cell and Developmental Biology

Yi, Y. and Zhu, H. and Klausen, C. and Chang, H.-M. and Inkster, A.M. and Terry, J. and Leung, P.C.K.

The interleukin 6 trans-signaling increases prostaglandin E2production in human granulosa cells

Biology of Reproduction

Li, S.-J. and Chang, H.-M. and Xie, J. and Wang, J.H. and Yang, J. and Leung, P.C.K.

The BMP2 Signaling Axis Promotes Invasive Differentiation of Human Trophoblasts

Frontiers in Cell and Developmental Biology

You, J. and Wang, W. and Chang, H.-M. and Yi, Y. and Zhao, H. and Zhu, H. and Sun, Y. and Tang, M. and Wang, C. and Sang, Y. and Feng, G. and Cheng, S. and Leung, P.C.K. and Zhu, Y.-M.

TOX3 Promotes Ovarian Estrogen Synthesis: An RNA-Sequencing and Network Study

Frontiers in Endocrinology

Man, Y. and Zhao, R. and Gao, X. and Liu, Y. and Zhao, S. and Lu, G. and Chan, W.-Y. and Leung, P.C.K. and Bian, Y.

Roles of TGF- Superfamily Proteins in Extravillous Trophoblast Invasion

Trends in Endocrinology and Metabolism

Li, Y. and Yan, J. and Chang, H.-M. and Chen, Z.-J. and Leung, P.C.K.

TGF-1 inhibits microvascular-like formation by decreasing VCAM1 and ICAM1 via the upregulation of SNAIL in human granulosa cells

Molecular and Cellular Endocrinology

Li, H. and Chang, H.-M. and Lin, Y.-M. and Shi, Z. and Leung, P.C.K.

Study protocol for the Sino-Canadian Healthy Life Trajectories Initiative (SCHeLTI): A multicentre, cluster-randomised, parallel-group, superiority trial of a multifaceted community-family-mother-child intervention to prevent childhood overweight and obesity

BMJ Open

Wu, Y. and Marc, I. and Bouchard, L. and Ouyang, F. and Luo, Z.-C. and Fan, J. and Dubois, L. and Msse, B. and Zhang, J. and Leung, P.C.K. and Liao, X.P. and Herba, C.M. and Booij, L. and Shen, J. and Lewin, A. and Jiang, H. and Wang, L. and Xu, J. and Wu, W. and Sun, W. and Wu, J. and Li, H. and Lei, C. and Kozyrskyj, A. and Semenic, S. and Chaillet, N. and Fortier, I. and Masse, L. and Zhan, J. and Allard, C. and Knoppers, B. and Zawati, M. and Baillargeon, J.-P. and Velez, M.P. and Zhang, H. and Yu, Y. and Yu, W. and Ding, Y. and Vaillancourt, C. and Liu, H. and Tetu, A. and Fang, W. and Zhang, R. and Zhao, X. and Jin, Y. and Liu, X.-M. and Zhang, H. and Chen, Z. and Yang, X. and Hao, Y.-H. and Abdelouahab, N. and Fraser, W. and Huang, H.-F.

Raman spectroscopy of follicular fluid and plasma with machine-learning algorithms for polycystic ovary syndrome screening

Molecular and Cellular Endocrinology

Zhang, X. and Liang, B. and Zhang, J. and Hao, X. and Xu, X. and Chang, H.-M. and Leung, P.C.K. and Tan, J.

Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring

Scientific Reports

Lin, X.-H. and Gao, L. and Tian, S. and Klausen, C. and Guo, M.-X. and Gao, Q. and Liu, M.-E. and Wang, H. and Wu, D.-D. and Zhou, C.-L. and Yang, J. and Meng, Y. and Liu, Y. and Xu, G.-F. and Tan, Y.-J. and Ullah, K. and Zhu, Y.-M. and Fraser, W.D. and Sheng, J.-Z. and Leung, P.C.K. and Muglia, L.J. and Wu, Y.-T. and Huang, H.-F.

A Lancet Commission on 70 years of women's reproductive, maternal, newborn, child, and adolescent health in China

The Lancet

Qiao, J. and Wang, Y. and Li, X. and Jiang, F. and Zhang, Y. and Ma, J. and Song, Y. and Ma, J. and Fu, W. and Pang, R. and Zhu, Z. and Zhang, J. and Qian, X. and Wang, L. and Wu, J. and Chang, H.-M. and Leung, P.C.K. and Mao, M. and Ma, D. and Guo, Y. and Qiu, J. and Liu, L. and Wang, H. and Norman, R.J. and Lawn, J. and Black, R.E. and Ronsmans, C. and Patton, G. and Zhu, J. and Song, L. and Hesketh, T.

Connective tissue growth factor mediates bone Morphogenetic protein 2-induced increase in Hyaluronan production in Luteinized human Granulosa cells

Research Square

Bai, L. and Chang, H.-M. and Zhu, Y.-M. and Leung, P.C.K.

Melatonin improves the effect of cryopreservation on human oocytes by suppressing oxidative stress and maintaining the permeability of the oolemma.

Journal of pineal research

Zhang Z and Mu Y and Ding D and Zou W and Li X and Chen B and Leung PC and Chang HM and Zhu Q and Wang K and Xue R and Xu Y and Zou H and Zhou P and Wei Z and Cao Y

12 / 2020

Activin A increases human trophoblast invasion by upregulating integrin 1 through ALK4.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhu S and Li Z and Cui L and Ban Y and Leung PCK and Li Y and Ma J

11 / 2020

lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1.

Molecular therapy. Nucleic acids

Li D and Wang X and Dang Y and Zhang X and Zhao S and Lu G and Chan WY and Leung PCK and Qin Y

11 / 2020

GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin-Like 3 Through the ALK5-SMAD2/3 Signaling Pathway.

Frontiers in cell and developmental biology

Xie J and Zhu H and Chang HM and Klausen C and Dong M and Leung PCK

10 / 2020

Gonadotropin-releasing hormone analogs: Mechanisms of action and clinical applications in female reproduction.

Frontiers in neuroendocrinology

Wu HM and Chang HM and Leung PCK

10 / 2020

BMP2 increases the production of BDNF through the upregulation of proBDNF and furin expression in human granulosa-lutein cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Bai L and Chang HM and Zhang L and Zhu YM and Leung PCK

10 / 2020

The p38 signaling pathway mediates the TGF-1-induced increase in type I collagen deposition in human granulosa cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li H and Chang HM and Shi Z and Leung PCK

09 / 2020

ALK3-SMAD1/5 Signaling Mediates the BMP2-Induced Decrease in PGE2 Production in Human Endometrial Stromal Cells and Decidual Stromal Cells.

Frontiers in cell and developmental biology

Zhang Y and Zhu H and Chang HM and Leung PCK

09 / 2020

The regulation of IGFBP3 by BMP2 has a role in human endometrial remodeling.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Luo J and Zhu H and Chang HM and Lin YM and Yang J and Leung PCK

09 / 2020

Epidermal growth factor promotes stromal cells migration and invasion via up-regulation of hyaluronate synthase 2 and hyaluronan in endometriosis.

Fertility and sterility

Zhan H and Peng B and Ma J and Lin K and Xu K and Lin J and Yong PJ and Leung PCK and Bedaiwy MA and Lin J

08 / 2020

NPFF increases fusogenic proteins syncytin 1 and syncytin 2 via GCM1 in first trimester primary human cytotrophoblast cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhu H and Peng B and Klausen C and Yi Y and Li Y and Xiong S and von Dadelszen P and Leung PCK

06 / 2020

Long noncoding RNA HCP5 participates in premature ovarian insufficiency by transcriptionally regulating MSH5 and DNA damage repair via YB1.

Nucleic acids research

Wang X and Zhang X and Dang Y and Li D and Lu G and Chan WY and Leung PCK and Zhao S and Qin Y and Chen ZJ

05 / 2020

TGF-1 induces VEGF expression in human granulosa-lutein cells: a potential mechanism for the pathogenesis of ovarian hyperstimulation syndrome.

Experimental & molecular medicine

Fang L and Li Y and Wang S and Li Y and Chang HM and Yi Y and Yan Y and Thakur A and Leung PCK and Cheng JC and Sun YP

03 / 2020

Adjuvant treatment strategies in ovarian stimulation for poor responders undergoing IVF: a systematic review and network meta-analysis.

Human reproduction update

Zhang Y and Zhang C and Shu J and Guo J and Chang HM and Leung PCK and Sheng JZ and Huang H

02 / 2020

Loss of CDYL Results in Suppression of CTNNB1 and Decreased Endometrial Receptivity.

Frontiers in cell and developmental biology

Zhou X and Xu B and Zhang D and Jiang X and Chang HM and Leung PCK and Xia X and Zhang A

02 / 2020

ALK4-SMAD3/4 mediates the effects of activin A on the upregulation of PAI-1 in human granulosa lutein cells.

Molecular and cellular endocrinology

Chen B and Chang HM and Zhang Z and Cao Y and Leung PCK

01 / 2020

Transvaginal ovarian drilling followed by controlled ovarian stimulation from the next day improves ovarian response for the poor responders with polycystic ovary syndrome during IVF treatment: a pilot study.

Reproductive Biology and Endocrinology : RB&E

Xu B and Zhou M and Cheng M and Zhang D and Wu X and Si C and Xia L and Xu H and Li J and Chang HM and Leung PCK and Zhang A

01 / 2020

TGF-1 promotes vitamin D-induced prostaglandin E2 synthesis by upregulating vitamin D receptor expression in human granulosa-lutein cells.

American journal of physiology. Endocrinology and metabolism

Wang F and Chang HM and Yi Y and Lin YM and Li H and Leung PCK

01 / 2020

Bone morphogenetic protein 2 promotes human trophoblast cell invasion and endothelial-like tube formation through ID1-mediated upregulation of IGF binding protein-3.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Zhao HJ and Klausen C and Zhu H and Chang HM and Li Y and Leung PCK

01 / 2020

TGF-1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

Cells

Jingwen Yin and Hsun-Ming Chang and Yuyin Yi and Yuanqing Yao and Peter C.K. Leung

01 / 2020

Corrigendum. Decreased PECAM1-mediated TGF-1 expression in the mid-secretory endometrium in women with recurrent implantation failure.

Human reproduction (Oxford, England)

Guo F and Si C and Zhou M and Wang J and Zhang D and Leung PCK and Xu B and Zhang A

01 / 2020

Erratum: Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer (Journal of Cell Science (2008) 121 (664-674) DOI: 10.1242/jcs.013029)

Journal of Cell Science

Astanehe, A. and Arenillas, D. and Wasserman, W.W. and Leung, P.C.K. and Dunn, S.E. and Davies, B.R. and Mills, G.B. and Auersperg, N.

CCN2 Mediates S1P-Induced Upregulation of COX2 Expression in Human Granulosa-Lutein Cells.

Cells

Hu LL and Chang HM and Yi Y and Liu Y and Taylor EL and Zheng LP and Leung PCK

11 / 2019

Bone morphogenetic protein 2 induces the activation of WNT/-catenin signaling and human trophoblast invasion through up-regulating BAMBI.

Cellular signalling

Zhao HJ and Chang HM and Klausen C and Zhu H and Li Y and Leung PCK

11 / 2019

Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite.

Scientific reports

Zhu Y and Klausen C and Zhou J and Guo X and Zhang Y and Zhu H and Li Z and Cheng JC and Xie S and Yang W and Li Y and Leung PCK

10 / 2019

Betacellulin enhances ovarian cancer cell migration by up-regulating Connexin43 via MEK-ERK signaling.

Cellular signalling

Zhao J and Klausen C and Yi Y and Cheng JC and Chang HM and Leung PCK

10 / 2019

TGF-1 promotes hyaluronan synthesis by upregulating hyaluronan synthase 2 expression in human granulosa-lutein cells.

Cellular signalling

Wang F and Chang HM and Yi Y and Li H and Leung PCK

08 / 2019

Bone morphogenetic protein 6 affects cell-cell communication by altering the expression of Connexin43 in human granulosa-lutein cells.

Molecular and cellular endocrinology

Wu HC and Chang HM and Yi Y and Sun ZG and Lin YM and Lian F and Leung PCK

08 / 2019

Kisspeptin regulation of human decidual stromal cells motility via FAK-Src intracellular tyrosine kinases.

Human reproduction (Oxford, England)

Wu HM and Huang HY and Soong YK and Leung PCK and Wang HS

07 / 2019

ID3 mediates the TGF-1-induced suppression of matrix metalloproteinase-1 in human granulosa cells.

The FEBS journal

Li H and Chang HM and Shi Z and Leung PCK

06 / 2019

Identification of potential metabolic biomarkers of polycystic ovary syndrome in follicular fluid by SWATH mass spectrometry.

Reproductive biology and endocrinology : RB&E

Sun Z and Chang HM and Wang A and Song J and Zhang X and Guo J and Leung PCK and Lian F

06 / 2019

SMAD-dependent signaling mediates BMP6-induced stimulation of connective tissue growth factor in luteinized human granulosa cells.

Biology of reproduction

Liu S and Chang HM and Yi Y and Yao YQ and Leung PCK

06 / 2019

ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells.

Molecular and cellular endocrinology

Liu C and Chang HM and Yi Y and Fang Y and Zhao F and Leung PCK and Yang X

06 / 2019

Activin A promotes ovarian cancer cell migration by suppressing E-cadherin expression.

Experimental cell research

Yi Y and Cheng JC and Klausen C and Leung PCK

06 / 2019

Lapatinib Inhibits Amphiregulin-induced BeWo Choriocarcinoma Cell Proliferation by Reducing ERK1/2 and AKT Signaling Pathways.

Anticancer research

Pires LV and Yi Y and Cheng JC and Pizzolato LS and Cordero E and Leung PCK and Brum IS

05 / 2019

The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome.

The Journal of clinical endocrinology and metabolism

Li M and Zhao H and Zhao SG and Wei DM and Zhao YR and Huang T and Muhammad T and Yan L and Gao F and Li L and Lu G and Chan WY and Leung PCK and Dunaif A and Liu HB and Chen ZJ

04 / 2019

Palmitic acid causes insulin resistance in granulosa cells via activation of JNK.

Journal of molecular endocrinology

Xu L and Wang W and Zhang X and Ke H and Qin Y and You L and Li W and Lu G and Chan WY and Leung PCK and Zhao S and Chen ZJ

03 / 2019

Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications.

Human reproduction update

Chang HM and Wu HC and Sun ZG and Lian F and Leung PCK

03 / 2019

BMP6 increases TGF-1 production by up-regulating furin expression in human granulosa-lutein cells.

Cellular signalling

Zhang XY and Chang HM and Zhu H and Liu RZ and Leung PCK

01 / 2019

Cell-Cell Interactions in Ovarian Follicles: Role of TGF- Superfamily Members

The Ovary

Hsun-Ming Chang and Yi-Min Zhu and Peter C.K. Leung

Maternal Hyperlipidemia Mediates Elevated Blood Pressure in Offspring Associated with Reprogramming Leptin Levels

SSRN

Lin, X.-H. and Xiong, Y.-M. and Tian, S. and Klausen, C. and Guo, M.-X. and Gao, Q. and Liu, M.-E. and Wang, H. and Gao, L. and Wu, D.-D. and Zhou, C.-L. and Yang, J. and Meng, Y. and Liu, Y. and Xu, G.-F. and Lu, Y.-C. and Tan, Y.-J. and Ullah, K. and Zhu, Y.-M. and Fraser, W.D. and Sheng, J.-Z. and Leung, P.C.K. and Muglia, L.J. and Wu, Y.-T. and Huang, H.-F.

Bone morphogenetic protein 2 increases lysyl oxidase activity via up-regulation of snail in human granulosa-lutein cells.

Cellular signalling

Bai L and Chang HM and Zhu YM and Leung PCK

10 / 2018

GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability.

The Journal of clinical endocrinology and metabolism

Cui L and Fang L and Mao X and Chang HM and Leung PCK and Ye Y

07 / 2018

Increased AIF-1-mediated TNF-a expression during implantation phase in IVF cycles with GnRH antagonist protocol.

Human reproduction (Oxford, England)

Xu B and Zhou M and Wang J and Zhang D and Guo F and Si C and Leung PCK and Zhang A

07 / 2018

Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A Production.

Endocrinology

Zhao HJ and Chang HM and Zhu H and Klausen C and Li Y and Leung PCK

07 / 2018

miR-106a Increases Granulosa Cell Viability and Is Downregulated in Women With Diminished Ovarian Reserve.

The Journal of clinical endocrinology and metabolism

Hong L and Peng S and Li Y and Fang Y and Wang Q and Klausen C and Yin C and Wang S and Leung PCK and Yang X

06 / 2018

TGF-1 inhibits human trophoblast cell invasion by upregulating cyclooxygenase-2.

Placenta

Yi Y and Cheng JC and Klausen C and Leung PCK

06 / 2018

Follicular localization of growth differentiation factor 8 and its receptors in normal and polycystic ovary syndrome ovaries.

Biology of reproduction

Lin TT and Chang HM and Hu XL and Leung PCK and Zhu YM

05 / 2018

BMP6 Downregulates GDNF Expression Through SMAD1/5 and ERK1/2 Signaling Pathways in Human Granulosa-Lutein Cells

Endocrinology

Xin-Yue Zhang and Hsun-Ming Chang and Elizabeth L Taylor and Rui-Zhi Liu and Peter C K Leung

05 / 2018

Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial.

Pregnancy hypertension

von Dadelszen P and Magee LA and Benton SJ and Hu Y and Ansermino JM and Carleton B and Carter C and Douglas MJ and Janssen PA and Lee SK and Leung PCK and Li J and MacNab Y and Payne BA and Russell JA

05 / 2018

Decreased PECAM1-mediated TGF-1 expression in the mid-secretory endometrium in women with recurrent implantation failure.

Human reproduction (Oxford, England)

Guo F and Si C and Zhou M and Wang J and Zhang D and Leung PCK and Xu B and Zhang A

05 / 2018

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling.

Cell death & disease

Zhao HJ and Klausen C and Li Y and Zhu H and Wang YL and Leung PCK

02 / 2018

SNAIL Mediates TGF-1"Induced Downregulation of Pentraxin 3 Expression in Human Granulosa Cells

Endocrinology

Hui Li and Hsun-Ming Chang and Zhendan Shi and Peter C K Leung

02 / 2018

Metabolomic Markers of Essential Fatty Acids, Carnitine, and Cholesterol Metabolism in Adults and Adolescents with Phenylketonuria.

The Journal of nutrition

02 / 2018

BMP6 Increases TGF-Beta1 Production by Up-Regulating Furin Expression in Human Granulosa-Lutein Cells

SSRN

Zhang, X.-Y. and Chang, H.-M. and Zhu, H. and Liu, R.-Z. and Leung, P.C.K.

Oocyte-somatic cell interactions in the human ovary-novel role of bone morphogenetic proteins and growth differentiation factors

Journal of Nutrition

Chang, H.-M. and Qiao, J. and Leung, P.C.K.

Human reproductive and prenatal genetics

Human Reproductive and Prenatal Genetics

Leung, P.C.K. and Qiao, J.

Physiological roles of activins in the human ovary

Journal of Bio-X Research

Chang, H.-M. and Leung, P.C.K.

TGF-1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation.

Cellular signalling

Cheng JC and Yi Y and Chang HM and Leung PCK

12 / 2017

Connective tissue growth factor mediates TGF-1-induced low-grade serous ovarian tumor cell apoptosis

Oncotarget

10 / 2017

SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells

Cellular Signalling

Long Bai and Hsun-Ming Chang and Jung-Chien Cheng and Christian Klausen and Guiyan Chu and Peter C.K. Leung and Gongshe Yang

09 / 2017

Lithium chloride inhibits StAR and progesterone production through GSK-3 and ERK1/2 signaling pathways in human granulosa-lutein cells.

Molecular and cellular endocrinology

09 / 2017

Phoenixin-14 concentrations are increased in association with luteinizing hormone and nesfatin-1 concentrations in women with polycystic ovary syndrome.

Clinica chimica acta; international journal of clinical chemistry

08 / 2017

Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3/-Catenin Signaling Pathway

Endocrinology

Long Bai and Hsun-Ming Chang and Jung-Chien Cheng and Guiyan Chu and Peter C K Leung and Gongshe Yang

07 / 2017

TGF-1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression

Endocrinology

Jung-Chien Cheng and Hsun-Ming Chang and Peter C. K Leung

07 / 2017

ALK2/ALK3-BMPR2/ACVR2A Mediate BMP2-Induced Downregulation of Pentraxin 3 Expression in Human Granulosa-Lutein Cells

Endocrinology

Long Bai and Hsun-Ming Chang and Jung-Chien Cheng and Guiyan Chu and Peter C. K Leung and Gongshe Yang

07 / 2017

TGF1 induces endometrial cancer cell adhesion and migration by up-regulating integrin av3 via SMAD-independent MEK-ERK1/2 signaling

Cellular Signalling

Siyuan Xiong and Christian Klausen and Jung-Chien Cheng and Peter C.K. Leung

06 / 2017

Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling

Oncotarget

Qianlan Fan and Yuan Cheng and Hsun-Ming Chang and Masashi Deguchi and Aaron J. Hsueh and Peter C.K. Leung

04 / 2017

Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism.

EBioMedicine

02 / 2017

Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression

Oncotarget

Hsien-Ming Wu and Hong-Yuan Huang and Andrew V. Schally and Angel Chao and Hung-Hsueh Chou and Peter C.K. Leung and Hsin-Shih Wang

01 / 2017

HOXB4 Immunoreactivity in Endometrial Tissues From Women With or Without Endometriosis.

Reproductive sciences (Thousand Oaks, Calif.)

01 / 2017

Growth differentiation factor 8 induces SKOV3 ovarian cancer cell migration and E-cadherin down-regulation

Cellular Signalling

Jianfang Zhao and Christian Klausen and Siyuan Xiong and Jung-Chien Cheng and Hsun-Ming Chang and Peter C.K. Leung

11 / 2016

Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells

Oncotarget

Jung-Chien Cheng and Hsun-Ming Chang and Siyuan Xiong and Wai-Kin So and Peter C. K. Leung

11 / 2016

Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus.

The Journal of clinical endocrinology and metabolism

11 / 2016

Connective tissue growth factor mediates growth differentiation factor 8-induced increase of lysyl oxidase activity in human granulosa-lutein cells

Molecular and Cellular Endocrinology

Hsun-Ming Chang and Ying Fang and Pang-Pin Liu and Jung-Chien Cheng and Xiaokui Yang and Peter C.K. Leung

10 / 2016

Activin A upregulates PTGS2 expression and increases PGE2 production in human granulosa-lutein cells

Reproduction

Pang-Pin Liu and Hsun-Ming Chang and Jung-Chien Cheng and Peter C K Leung

09 / 2016

Activin A-induced increase in LOX activity in human granulosa"lutein cells is mediated by CTGF

Reproduction

Hsun-Ming Chang and Jung-Chien Cheng and Yingtao Liu and Christian Klausen and Congjian Xu and Peter C K Leung

08 / 2016

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways

Oncotarget

Siyuan Xiong and Jung-Chien Cheng and Christian Klausen and Jianfang Zhao and Peter C.K. Leung

08 / 2016

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

07 / 2016

Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling

Cellular Signalling

Jung-Chien Cheng and Hsun-Ming Chang and Pang-Pin Liu and Peter C.K. Leung

06 / 2016

Transforming growth factor-1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells

Reproduction

Ying Fang and Hsun-Ming Chang and Jung-Chien Cheng and Christian Klausen and Peter C K Leung and Xiaokui Yang

06 / 2016

Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor are expressed at tubal ectopic pregnancy implantation sites

Fertility and Sterility

Bo Peng and Christian Klausen and Lisa Campbell and Peter C.K. Leung and Andrew W. Horne and Mohamed A. Bedaiwy

06 / 2016

Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells.

Molecular and cellular endocrinology

06 / 2016

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells.

Oncotarget

05 / 2016

Whole exome sequencing in recurrent early pregnancy loss.

Molecular human reproduction

05 / 2016

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling

Oncotarget

Siyuan Xiong and Christian Klausen and Jung-Chien Cheng and Peter C.K. Leung

05 / 2016

Growth differentiation factor 8 suppresses cell proliferation by up-regulating CTGF expression in human granulosa cells

Molecular and Cellular Endocrinology

Hsun-Ming Chang and Hui-Hui Pan and Jung-Chien Cheng and Yi-Min Zhu and Peter C.K. Leung

02 / 2016

Effects of growth differentiation factor 8 on steroidogenesis in human granulosa-lutein cells

Fertility and Sterility

Hsun-Ming Chang and Lanlan Fang and Jung-Chien Cheng and Elizabeth L. Taylor and Ying-Pu Sun and Peter C.K. Leung

02 / 2016

EGF-Induced Connexin43 Negatively Regulates Cell Proliferation in Human Ovarian Cancer.

Journal of cellular physiology

01 / 2016

Bone morphogenetic protein 2 regulates cell"cell communication by down-regulating connexin43 expression in luteinized human granulosa cells

Molecular Human Reproduction

Yan-Ting Wu and Hsun-Ming Chang and He-Feng Huang and Jian-Zhong Sheng and Peter C.K. Leung

Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line.

Current molecular medicine

hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS.

Scientific reports

BMP4 and BMP7 Suppress StAR and Progesterone Production via ALK3 and SMAD1/5/8-SMAD4 in Human Granulosa-Lutein Cells

Endocrinology

Han Zhang and Christian Klausen and Hua Zhu and Hsun-Ming Chang and Peter C. K. Leung

11 / 2015

Vascular Endothelial Growth Factor-A (VEGF-A) Mediates Activin A-Induced Human Trophoblast Endothelial-Like Tube Formation

Endocrinology

Yan Li and Hua Zhu and Christian Klausen and Bo Peng and Peter C. K. Leung

11 / 2015

Activin A Increases Human Trophoblast Invasion by Inducing SNAIL-Mediated MMP2 Up-Regulation Through ALK4

The Journal of Clinical Endocrinology & Metabolism

Yan Li and Christian Klausen and Hua Zhu and Peter C. K. Leung

11 / 2015

Transforming growth factor- stimulates human ovarian cancer cell migration by up-regulating connexin43 expression via Smad2/3 signaling

Cellular Signalling

Xin Qiu and Jung-Chien Cheng and Jianfang Zhao and Hsun-Ming Chang and Peter C.K. Leung

10 / 2015

Activin A, B and AB decrease progesterone production by down-regulating StAR in human granulosa cells.

Molecular and cellular endocrinology

09 / 2015

CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells.

Cell death & disease

08 / 2015

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

Oncotarget

Siyuan Xiong and Christian Klausen and Jung-Chien Cheng and Hua Zhu and Peter C.K. Leung

08 / 2015

Transforming growth factor-1 up-regulates connexin43 expression in human granulosa cells

Human Reproduction

Yu-Ching Chen and Hsun-Ming Chang and Jung-Chien Cheng and Horng-Der Tsai and Cheng-Hsuan Wu and Peter C.K. Leung

07 / 2015

AP-1 Transcription Factors c-FOS and c-JUN Mediate GnRH-Induced Cadherin-11 Expression and Trophoblast Cell Invasion

Endocrinology

Bo Peng and Hua Zhu and Liyang Ma and Yan-ling Wang and Christian Klausen and Peter C. K. Leung

06 / 2015

TGF-1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways

PLOS ONE

Jung-Chien Cheng and Hsun-Ming Chang and Lanlan Fang and Ying-Pu Sun and Peter C. K. Leung

05 / 2015

Transforming growth factor-a induces human ovarian cancer cell invasion by down-regulating E-cadherin in a Snail-independent manner.

Biochemical and biophysical research communications

05 / 2015

Gonadotropin-Releasing Hormone Type II (GnRH-II) Agonist Regulates the Motility of Human Decidual Endometrial Stromal Cells: Possible Effect on Embryo Implantation and Pregnancy

Biology of Reproduction

04 / 2015

Alternative splicing of the androgen receptor in polycystic ovary syndrome.

Proceedings of the National Academy of Sciences of the United States of America

04 / 2015

Growth differentiation factor 8 down-regulates pentraxin 3 in human granulosa cells

Molecular and Cellular Endocrinology

Hsun-Ming Chang and Lanlan Fang and Jung-Chien Cheng and Christian Klausen and Ying-Pu Sun and Peter C.K. Leung

03 / 2015

TGF-1 up-regulates connexin43 expression: A potential mechanism for human trophoblast cell differentiation

Journal of Cellular Physiology

Jung-Chien Cheng and Hsun-Ming Chang and Lanlan Fang and Ying-Pu Sun and Peter C.K. Leung

03 / 2015

Recombinant BMP4 and BMP7 Downregulate Pentraxin 3 in Human Granulosa Cells

The Journal of Clinical Endocrinology & Metabolism

Hsun-Ming Chang and Jung-Chien Cheng and Lanlan Fang and Xin Qiu and Christian Klausen and Elizabeth L. Taylor and Peter C.K. Leung

03 / 2015

Recombinant BMP4 and BMP7 Increase Activin A Production by Up-Regulating Inhibin A Subunit and Furin Expression in Human Granulosa-Lutein Cells

The Journal of Clinical Endocrinology & Metabolism

Hsun-Ming Chang and Jung-Chien Cheng and Christian Klausen and Peter C.K. Leung

03 / 2015

EpCAM is up-regulated by EGF via ERK1/2 signaling and suppresses human epithelial ovarian cancer cell migration.

Biochemical and biophysical research communications

02 / 2015

Nitric Oxide and cGMP Induce COX-2 Expression and PGE2Production in Human Granulosa Cells Through CREB Signaling Pathway

The Journal of Clinical Endocrinology & Metabolism

Lanlan Fang and Hsun-Ming Chang and Jung-Chien Cheng and Peter C. K. Leung and Ying-Pu Sun

02 / 2015

Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion.

FEBS letters

01 / 2015

Gonadotropin-Releasing Hormone Regulates Human Trophoblastic Cell Invasion via TWIST-Induced N-cadherin Expression

The Journal of Clinical Endocrinology & Metabolism

Bo Peng and Hua Zhu and Peter C.K. Leung

01 / 2015

GnRH regulates trophoblast invasion via RUNX2-mediated MMP2/9 expression

Molecular Human Reproduction

Bo Peng and Hua Zhu and Christian Klausen and Liyang Ma and Yan-ling Wang and Peter C.K. Leung

Functional consequences of copy number variants in miscarriage.

Molecular cytogenetics

Growth Differentiation Factor-8 Decreases StAR Expression Through ALK5-Mediated Smad3 and ERK1/2 Signaling Pathways in Luteinized Human Granulosa Cells

Endocrinology

Lanlan Fang and Hsun-Ming Chang and Jung-Chien Cheng and Yiping Yu and Peter C. K. Leung and Ying-Pu Sun

Activin A, B, and AB Increase Human Trophoblast Cell Invasion by Up-regulating N-Cadherin

The Journal of Clinical Endocrinology & Metabolism

Yan Li and Christian Klausen and Jung-Chien Cheng and Hua Zhu and Peter C. K. Leung

11 / 2014

TGF-1 Downregulates StAR Expression and Decreases Progesterone Production Through Smad3 and ERK1/2 Signaling Pathways in Human Granulosa Cells

The Journal of Clinical Endocrinology & Metabolism

Lanlan Fang and Hsun-Ming Chang and Jung-Chien Cheng and Peter C. K. Leung and Ying-Pu Sun

11 / 2014

Amphiregulin induces human ovarian cancer cell invasion by down-regulating E-cadherin expression.

FEBS letters

11 / 2014

Effects of Recombinant Activins on Steroidogenesis in Human Granulosa-Lutein Cells

The Journal of Clinical Endocrinology & Metabolism

Hsun-Ming Chang and Jung-Chien Cheng and Christian Klausen and Elizabeth L. Taylor and Peter C. K. Leung

10 / 2014

COX2 and PGE2 mediate EGF-induced E-cadherin-independent human ovarian cancer cell invasion.

Endocrine-related cancer

08 / 2014

TGF-1 Induces COX-2 Expression and PGE2 Production in Human Granulosa Cells Through Smad Signaling Pathways

The Journal of Clinical Endocrinology & Metabolism

Lanlan Fang and Hsun-Ming Chang and Jung-Chien Cheng and Peter C. K. Leung and Ying-Pu Sun

07 / 2014

Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells.

Molecular human reproduction

05 / 2014

FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors

Biochemical and Biophysical Research Communications

Jung-Chien Cheng and Hsun-Ming Chang and Xin Qiu and Lanlan Fang and Peter C.K. Leung

01 / 2014

Correction: Fibroblast Growth Factor 2 Induces E-Cadherin Down-Regulation via PI3K/Akt/mTOR and MAPK/ERK Signaling in Ovarian Cancer Cells.

PloS one

Lau M and So W and Leung PCK

12 / 2013

Transforming growth factor-1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein.

The Journal of biological chemistry

11 / 2013

Homeobox A7 stimulates breast cancer cell proliferation by up-regulating estrogen receptor-alpha

Biochemical and Biophysical Research Communications

Yu Zhang and Jung-Chien Cheng and He-Feng Huang and Peter C.K. Leung

11 / 2013

Gonadal steroids regulate the expression of aggrecanases in human endometrial stromal cellsin vitro

Journal of Cellular and Molecular Medicine

Jiadi Wen and Hua Zhu and Peter C.K. Leung

08 / 2013

Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2.

BMC cancer

06 / 2013

HER2 mediates epidermal growth factor-induced down-regulation of E-cadherin in human ovarian cancer cells.

Biochemical and biophysical research communications

04 / 2013

Theca-Derived BMP4 and BMP7 Down-Regulate Connexin43 Expression and Decrease Gap Junction Intercellular Communication Activity in Immortalized Human Granulosa Cells

The Journal of Clinical Endocrinology & Metabolism

Hsun-Ming Chang and Jung-Chien Cheng and Peter C. K. Leung

03 / 2013

Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways.

Molecular human reproduction

03 / 2013

Hypoxia-inducible factor 1 alpha mediates epidermal growth factor-induced down-regulation of E-cadherin expression and cell invasion in human ovarian cancer cells

Cancer Letters

Jung-Chien Cheng and Christian Klausen and Peter C.K. Leung

02 / 2013

Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells.

Oncogene

02 / 2013

Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors.

Journal of cellular and molecular medicine

01 / 2013

Targeting Gonadotropin-releasing Hormone Receptor Inhibits the Early Step of Ovarian Cancer Metastasis by Modulating Tumor-mesothelial Adhesion

Molecular Therapy

Lydia WT Cheung and Susan Yung and Tak-Mao Chan and Peter CK Leung and Alice ST Wong

01 / 2013

Overexpression of Wild-Type but Not C134W Mutant FOXL2 Enhances GnRH-Induced Cell Apoptosis by Increasing GnRH Receptor Expression in Human Granulosa Cell Tumors

PLoS ONE

Jung-Chien Cheng and Christian Klausen and Peter C. K. Leung

01 / 2013

Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells.

PloS one

BMP15 Suppresses Progesterone Production by Down-Regulating StAR via ALK3 in Human Granulosa Cells

Molecular Endocrinology

Hsun-Ming Chang and Jung-Chien Cheng and Christian Klausen and Peter C. K. Leung

EGF-like Growth Factors Induce COX-2"Derived PGE2 Production Through ERK1/2 in Human Granulosa Cells

The Journal of Clinical Endocrinology & Metabolism

Lanlan Fang and Jung-Chien Cheng and Hsun-Ming Chang and Ying-Pu Sun and Peter C. K. Leung

Antimllerian hormone inhibits follicle-stimulating hormone-induced adenylyl cyclase activation, aromatase expression, and estradiol production in human granulosa-lutein cells

Fertility and Sterility

Chang, H.-M. and Klausen, C. and Leung, P.C.K.

Epidermal Growth Factor Induces Human Oviductal Epithelial Cell Invasion by Down-Regulating E-Cadherin Expression

The Journal of Clinical Endocrinology & Metabolism

Jung-Chien Cheng and Hsun-Ming Chang and Peter C. K. Leung

08 / 2012

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.

Journal of molecular medicine (Berlin, Germany)

08 / 2012

TGF-Beta Induces Serous Borderline Ovarian Tumor Cell Invasion by Activating EMT but Triggers Apoptosis in Low-Grade Serous Ovarian Carcinoma Cells

PLoS ONE

Jung-Chien Cheng and Nelly Auersperg and Peter C. K. Leung

08 / 2012

The Human Gonadotropin-Inhibitory Hormone Ortholog RFamide-Related Peptide-3 Suppresses Gonadotropin-Induced Progesterone Production in Human Granulosa Cells

Endocrinology

Hajime Oishi and Christian Klausen and George E. Bentley and Tomohiro Osugi and Kazuyoshi Tsutsui and C. Blake Gilks and Tetsu Yano and Peter C. K. Leung

07 / 2012

Integrin 1 mediates epithelial growth factor-induced invasion in human ovarian cancer cells

Cancer Letters

Man-Tat Lau and Wai-Kin So and Peter C.K. Leung

07 / 2012

Transgenerational glucose intolerance with Igf2/H19 epigenetic alterations in mouse islet induced by intrauterine hyperglycemia.

Diabetes

05 / 2012

Gonadotropin-Releasing Hormone-I or -II Interacts with IGF-I/Akt But Not Connexin 43 in Human Granulosa Cell Apoptosis

The Journal of Clinical Endocrinology & Metabolism

In-Sun Hong and C. Klausen and Anthony P. Cheung and Peter C. K. Leung

02 / 2012

Twist Modulates Human Trophoblastic Cell Invasion via Regulation of N-Cadherin

Endocrinology

York Hunt Ng and Hua Zhu and Peter C. K. Leung

02 / 2012

Gonadotrophin-releasing hormone antagonist induces apoptosis in human decidual stromal cells: effect on GADD45 and MAPK signaling

Human Reproduction

H.-M. Wu and H.-S. Wang and Y.-K. Soong and H.-Y. Huang and C.-K. Chen and C.-L. Lee and P. C. K. Leung

01 / 2012

The PI3K/Akt/mTOR signaling pathway mediates insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells

Cancer Letters

Man-Tat Lau and Peter C.K. Leung

EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?

PloS one

Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.

Oncogene

09 / 2011

Identification of Estrogen Response Element in the Aquaporin-2 Gene That Mediates Estrogen-Induced Cell Migration and Invasion in Human Endometrial Carcinoma

The Journal of Clinical Endocrinology & Metabolism

Li-Bo Zou and Run-Ju Zhang and Ya-Jing Tan and Guo-Lian Ding and Shuai Shi and Dan Zhang and Rong-Huan He and Ai-Xia Liu and Ting-Ting Wang and Peter C. K. Leung and Jian-Zhong Sheng and He-Feng Huang

09 / 2011

Wild-Type p53 Attenuates Cancer Cell Motility by Inducing Growth Differentiation Factor-15 Expression

Endocrinology

Jung-Chien Cheng and Hsun-Ming Chang and Peter C. K. Leung

08 / 2011

Growth Differentiation Factor 9 (GDF9) Suppresses Follistatin and Follistatin-Like 3 Production in Human Granulosa-Lutein Cells

PLoS ONE

Feng-Tao Shi and Anthony P. Cheung and He-Feng Huang and Peter C. K. Leung

08 / 2011

Anti-Mullerian Hormone Inhibits FSH-Induced Adenylyl Cyclase Activation, Aromatase Expression, and Estradiol Production in Human Granulosa-Lutein Cells.

Biology of Reproduction

Hsun Ming Chang and Christian Klausen and Peter C.K. Leung

07 / 2011

E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via -catenin-Egr1-mediated PTEN expression.

Oncogene

06 / 2011

P-cadherin cooperates with insulin-like growth factor-1 receptor to promote metastatic signaling of gonadotropin-releasing hormone in ovarian cancer via p120 catenin.

Oncogene

06 / 2011

Type I collagen down-regulates E-cadherin expression by increasing PI3KCA in cancer cells.

Cancer letters

05 / 2011

Regulated expression of ADAMTS-12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?

PloS one

04 / 2011

Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin.

Oncogene

03 / 2011

Gonadotropin-Releasing Hormone-II Increases Membrane Type I Metalloproteinase Production via -Catenin Signaling in Ovarian Cancer Cells

Endocrinology

Song Ling Poon and Man-Tat Lau and Geoffrey L. Hammond and Peter C. K. Leung

03 / 2011

Sustained endoplasmic reticulum stress as a cofactor of oxidative stress in decidual cells from patients with early pregnancy loss.

The Journal of clinical endocrinology and metabolism

03 / 2011

37-kDa Laminin Receptor Precursor Mediates GnRH-II"Induced MMP-2 Expression and Invasiveness in Ovarian Cancer Cells

The Journal of Clinical Endocrinology & Metabolism

Song Ling Poon and Christian Klausen and Geoffrey L. Hammond and Peter C. K. Leung

02 / 2011

Twist Regulates Cadherin-Mediated Differentiation and Fusion of Human Trophoblastic Cells

The Journal of Clinical Endocrinology & Metabolism

York Hunt Ng and Hua Zhu and Peter C. K. Leung

Expression of calbindin-D28k and its regulation by estrogen in the human endometrium during the menstrual cycle

Reproductive Biology and Endocrinology

Hyun Yang and Tae-Hee Kim and Hae-Hyeog Lee and Kyung-Chul Choi and Yeon-pyo Hong and Peter CK Leung and Eui-Bae Jeung

37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells

Molecular Endocrinology

Poon, S.L. and Klausen, C. and Hammond, G.L. and Leung, P.C.K.

G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve

Fertility and Sterility

Ting-Ting Wang and Yan-Ting Wu and Min-Yue Dong and Jian-Zhong Sheng and Peter C.K. Leung and He-Feng Huang

11 / 2010

Growth Differentiation Factor 9 Reverses Activin A Suppression of Steroidogenic Acute Regulatory Protein Expression and Progesterone Production in Human Granulosa-Lutein Cells

The Journal of Clinical Endocrinology & Metabolism

Feng-Tao Shi and Anthony P. Cheung and Christian Klausen and He-Feng Huang and Peter C. K. Leung

10 / 2010

Hydrogen Peroxide Mediates EGF-Induced Down-Regulation of E-Cadherin Expression via p38 MAPK and Snail in Human Ovarian Cancer Cells

Molecular Endocrinology

Jung-Chien Cheng and Christian Klausen and Peter C. K. Leung

08 / 2010

Gonadotropins Induce Tumor Cell Migration and Invasion by Increasing Cyclooxygenases Expression and Prostaglandin E2Production in Human Ovarian Cancer Cells

Endocrinology

Man-Tat Lau and Alice S. T. Wong and Peter C. K. Leung

07 / 2010

Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.

Oncogene

04 / 2010

Gonadotropin-Releasing Hormone-I-Mediated Activation of Progesterone Receptor Contributes to Gonadotropin a-Subunit Expression in Mouse Gonadotrophs

Endocrinology

Junling Chen and Beum-Soo An and Wai-Kin So and Linan Cheng and Geoffrey L. Hammond and Peter C. K. Leung

03 / 2010

Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth

Cancer Science

Ki-Yon Kim and Seung U. Kim and Peter C. K. Leung and Eui-Bae Jeung and Kyung-Chul Choi

02 / 2010

Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia.

BJOG : an international journal of obstetrics and gynaecology

01 / 2010

Oviductal Glycoprotein (OVGP1, MUC9)

International Journal of Gynecological Cancer

Sarah Maines-Bandiera and Michelle M.M. Woo and Marilyn Borugian and Laurie L. Molday and Theresa Hii and Blake Gilks and Peter C.K. Leung and Robert S. Molday and Nelly Auersperg

01 / 2010

Antiproliferative effect of growth hormone-releasing hormone (GHRH) antagonist on ovarian cancer cells through the EGFR-Akt pathway

Reproductive Biology and Endocrinology

Jian Guo and Andrew V Schally and Marta Zarandi and Jozsef Varga and Peter CK Leung

Homeobox A7 increases cell proliferation by up-regulation of epidermal growth factor receptor expression in human granulosa cells

Reproductive Biology and Endocrinology

Yu Zhang and Qing Huang and Jung-Chien Cheng and Yoshihiro Nishi and Toshihiko Yanase and He-Feng Huang and Peter CK Leung

Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth

Carcinogenesis

Jung-Hye Choi and Kyung-Tae Lee and Peter C.K. Leung

Growth hormone-releasing hormone antagonist induces apoptosis of human endometrial cancer cells through PKCd-mediated activation of p53/p21

Cancer Letters

Hsien-Ming Wu and Andrew V. Schally and Jung-Chien Cheng and Marta Zarandi and Jozsef Varga and Peter C.K. Leung

Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.

Reproductive biology and endocrinology : RB&E

12 / 2009

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors.

PloS one

11 / 2009

Effects of Endogenous Growth Differentiation Factor 9 on Activin A-Induced Inhibin B Production in Human Granulosa-Lutein Cells.

Molecular endocrinology (Baltimore, Md.)

Shi F and Cheung AP and Huang H and Leung PCK

11 / 2009

Gonadotropin-Releasing Hormone-Mediated Phosphorylation of Estrogen Receptor-a Contributes to fosB Expression in Mouse Gonadotrophs

Endocrinology

10 / 2009

Cell Motility and Spreading Are Suppressed by HOXA4 in Ovarian Cancer Cells: Possible Involvement of 1 Integrin

Molecular Cancer Research

C. Klausen and P. C.K. Leung and N. Auersperg

09 / 2009

Epidermal Growth Factor-Induced GnRH-II Synthesis Contributes to Ovarian Cancer Cell Invasion

The Journal of Clinical Endocrinology & Metabolism

Song Ling Poon and Gareth T. Hammond and Peter C. K. Leung

09 / 2009

Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor.

Biology of reproduction

08 / 2009

Growth Differentiation Factor 9 Enhances Activin A-Induced Inhibin B Production in Human Granulosa Cells

Endocrinology

Feng-Tao Shi and Anthony P. Cheung and Peter C. K. Leung

08 / 2009

Clinical and endocrine response to the withdrawal of gonadotropin-releasing hormone agonists during prolonged coasting

Fertility and Sterility

Basil Ho Yuen and Tuan-Anh T. Nguyen and Anthony P. Cheung and Peter C.K. Leung

08 / 2009

Promotion of Human Trophoblasts Invasion by Gonadotropin-Releasing Hormone (GnRH) I and GnRH II via Distinct Signaling Pathways

Molecular Endocrinology

Jing Liu and Colin D. MacCalman and Yan-ling Wang and Peter C. K. Leung

07 / 2009

Mutation of FOXL2 in granulosa-cell tumors of the ovary.

The New England journal of medicine

06 / 2009

Effects of growth differentiation factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferation.

American journal of physiology. Endocrinology and metabolism

06 / 2009

Gonadotropin-releasing hormone type II induces apoptosis of human endometrial cancer cells by activating GADD45alpha.

Cancer research

05 / 2009

GnRH signaling in intrauterine tissues.

Reproduction (Cambridge, England)

05 / 2009

Gonadotropin-stimulated epidermal growth factor receptor expression in human ovarian surface epithelial cells: involvement of cyclic AMP-dependent exchange protein activated by cAMP pathway.

Endocrine-related cancer

03 / 2009

Expression and function of HOXA genes in normal and neoplastic ovarian epithelial cells

Differentiation

Takayo Ota and Christian Klausen and M. Clara Salamanca and Henry L. Woo and Peter C.K. Leung and Nelly Auersperg

02 / 2009

Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38.

The Journal of reproduction and development

02 / 2009

Effects of Endogenous Growth Differentiation Factor 9 on Activin A-Induced Inhibin B Production in Human Granulosa-Lutein Cells

The Journal of Clinical Endocrinology & Metabolism

Feng-Tao Shi and Anthony P. Cheung and He-Feng Huang and Peter C. K. Leung

Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: Involvement of integrin beta3 and focal adhesion kinase

Reproductive Biology and Endocrinology

Dong Park and Kyung-Chul Choi and Colin D MacCalman and Peter CK Leung

Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells

Reproductive Biology and Endocrinology

Lin, Q. and Poon, S.L. and Chen, J. and Cheng, L. and HoYuen, B. and Leung, P.C.K.

Transcripts of testicular gonadotropin-releasing hormone, steroidogenic enzymes, and intratesticular testosterone levels in infertile men

Fertility and Sterility

Yung Ming Lin and Song Ling Poon and Jung Hye Choi and Johnny Shinn Nan Lin and Peter C.K. Leung and Bu Miin Huang

11 / 2008

Temporal Recruitment of Transcription Factors at the 3',5'-Cyclic Adenosine 5'-Monophosphate-Response Element of the HumanGnRH-IIPromoter

Endocrinology

Song Ling Poon and Beum-Soo An and Wai-Kin So and Geoffrey L. Hammond and Peter C. K. Leung

10 / 2008

Gonadotropin-releasing hormone and ovarian cancer: a functional and mechanistic overview

FEBS Journal

Wai-Kin So and Jung-Chien Cheng and Song-Ling Poon and Peter C. K. Leung

10 / 2008

SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

Gynecologic oncology

10 / 2008

Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.

Molecular Endocrinology

09 / 2008

Gonadotropin-Releasing Hormones I and II Induce Apoptosis in Human Granulosa Cells

The Journal of Clinical Endocrinology & Metabolism

In-Sun Hong and Anthony P. Cheung and Peter C. K. Leung

08 / 2008

Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer.

Journal of cell science

03 / 2008

Progesterone receptor (PR) isoforms PRA and PRB differentially regulate expression of the breast cancer resistance protein in human placental choriocarcinoma BeWo cells.

Molecular pharmacology

03 / 2008

Regulation of Kruppel-like factor 4, 9, and 13 genes and the steroidogenic genes LDLR, StAR, and CYP11A in ovarian granulosa cells.

American journal of physiology. Endocrinology and metabolism

02 / 2008

Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

HOX cofactors expression and regulation in the human ovary

Reproductive Biology and Endocrinology

Takayo Ota and Haruka Asahina and Se-Hyung Park and Qing Huang and Takashi Minegishi and Nelly Auersperg and Peter CK Leung

HOXA7 in Epithelial Ovarian Cancer: Interrelationships Between Differentiation and Clinical Features

Reproductive Sciences

Takayo Ota and C. Blake Gilks and Teri Longacre and Peter C. K. Leung and Nelly Auersperg

09 / 2007

Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion

Endocrine

Chien-Lin Chen and Lydia W. T. Cheung and Man-Tat Lau and Jung-Hye Choi and Nelly Auersperg and Hsin-Shih Wang and Alice S. T. Wong and Peter C. K. Leung

07 / 2007

Gonadotropins and Ovarian Cancer

Endocrine Reviews

Jung-Hye Choi and Alice S. T. Wong and He-Feng Huang and Peter C. K. Leung

06 / 2007

Multiple roles of the candidate oncogeneZNF217in ovarian epithelial neoplastic progression

International Journal of Cancer

Peixiang Li and Sarah Maines-Bandiera and Wen-Lin Kuo and Yinghui Guan and Yu Sun and Mark Hills and Guiqing Huang and Collin C. Collins and Peter C.K. Leung and Joe W. Gray and Nelly Auersperg

05 / 2007

Involvement of NF-B subunit p65 and retinoic acid receptors, RARa and RXRa, in transcriptional regulation of the human GnRH II gene

FEBS Journal

Ruby L. C. Hoo and Kathy Y. Y. Chan and Francis K. Y. Leung and Leo T. O. Lee and Peter C. K. Leung and Billy K. C. Chow

04 / 2007

Role of endocrine and growth factors on the ovarian surface epithelium.

The journal of obstetrics and gynaecology research

02 / 2007

Expression of ADAMTS-5/implantin in human decidual stromal cells: regulatory effects of cytokines.

Human reproduction (Oxford, England)

01 / 2007

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma.

BMC medicine

Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9.

Cancer research

11 / 2006

Immunolocalization of Gonadotropin-Releasing Hormone (GnRH)-I, GnRH-II, and Type I GnRH Receptor during Follicular Development in the Human Ovary

The Journal of Clinical Endocrinology & Metabolism

Jung-Hye Choi and C. Blake Gilks and Nelly Auersperg and Peter C. K. Leung

11 / 2006

Endocrine signaling in ovarian surface epithelium and cancer

Human Reproduction Update

Peter C.K. Leung and Jung-Hye Choi

10 / 2006

Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid by gonadotropins in human immortalized ovarian surface epithelium and ovarian cancer cells.

Endocrine-related cancer

06 / 2006

Steroid Receptor Coactivator-3 Is Required for Progesterone Receptor Trans-activation of Target Genes in Response to Gonadotropin-releasing Hormone Treatment of Pituitary Cells

Journal of Biological Chemistry

Beum-Soo An and David M. Selva and Geoffrey L. Hammond and Adolfo Rivero-Muller and Nafis Rahman and Peter C. K. Leung

05 / 2006

Differential effects of interleukin-1 and transforming growth factor-1 on the expression of the inflammation-associated protein, ADAMTS-1, in human decidual stromal cells in vitro

Human Reproduction

York Hunt Ng and Hua Zhu and Catherine J. Pallen and Peter C.K. Leung and Colin D. MacCalman

05 / 2006

Gonadotropins Activate Proteolysis and Increase Invasion through Protein Kinase A and Phosphatidylinositol 3-Kinase Pathways in Human Epithelial Ovarian Cancer Cells

Cancer Research

Jung-Hye Choi and Kyung-Chul Choi and Nelly Auersperg and Peter C.K. Leung

04 / 2006

Mechanism of gonadotropin-releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway.

Endocrine-related cancer

03 / 2006

Cell type- and stage-specific changes in HOXA7 protein expression in human ovarian folliculogenesis: possible role of GDF-9.

Differentiation; research in biological diversity

02 / 2006

Impact of Environmental Endocrine Disruption on the Reproductive System for Human Health

Immunology Endocrine & Metabolic Agents in Medicinal Chemistry

Kyung-Chul Choi and Eui-Bae Jeung and Peter Leung

02 / 2006

Editorial

Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry

Leung, P.C.K.

Regulation of A Disintegrin And Metalloproteinase with ThromboSpondin Repeats-1 Expression in Human Endometrial Stromal Cells by Gonadal Steroids Involves Progestins, Androgens, and Estrogens

The Journal of Clinical Endocrinology & Metabolism

Jiadi Wen and Hua Zhu and Shuko Murakami and Peter C. K. Leung and Colin D. MacCalman

Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals.

Reproductive biology and endocrinology : RB&E

Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells.

Molecular human reproduction

11 / 2005

Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors.

Reproductive biology and endocrinology : RB&E

11 / 2005

Caspase-1a Is Down-regulated in Human Ovarian Cancer Cells and the Overexpression of Caspase-1a Induces Apoptosis

Cancer Research

Qiang Feng and Peixiang Li and Clara Salamanca and David Huntsman and Peter C.K. Leung and Nelly Auersperg

10 / 2005

GnRH in non-hypothalamic reproductive tissues

Animal Reproduction Science

N. Ramakrishnappa and R. Rajamahendran and Yung-Ming Lin and P.C.K. Leung

08 / 2005

Gonadotropins upregulate the epidermal growth factor receptor through activation of mitogen-activated protein kinases and phosphatidyl-inositol-3-kinase in human ovarian surface epithelial cells.

Endocrine-related cancer

06 / 2005

Molecular Biology of Gonadotropin-Releasing Hormone (GnRH)-I, GnRH-II, and Their Receptors in Humans

Endocrine Reviews

Chi Keung Cheng and Peter C. K. Leung

04 / 2005

Extracellular Signal-Regulated Protein Kinase, But Not c-Jun N-Terminal Kinase, Is Activated by Type II Gonadotropin-Releasing Hormone Involved in the Inhibition of Ovarian Cancer Cell Proliferation

The Journal of Clinical Endocrinology & Metabolism

Ki-Yon Kim and Kyung-Chul Choi and Se-Hyung Park and Nelly Auersperg and Peter C. K. Leung

03 / 2005

Differential Role of Progesterone Receptor Isoforms in the Transcriptional Regulation of Human Gonadotropin-Releasing Hormone I (GnRH I) Receptor, GnRH I, and GnRH II

The Journal of Clinical Endocrinology & Metabolism

Beum-Soo An and Jung-Hye Choi and Kyung-Chul Choi and Peter C. K. Leung

02 / 2005

Expression of Leptin Receptors and Potential Effects of Leptin on the Cell Growth and Activation of Mitogen-Activated Protein Kinases in Ovarian Cancer Cells

The Journal of Clinical Endocrinology & Metabolism

Jung-Hye Choi and Se-Hyung Park and Peter C. K. Leung and Kyung-Chul Choi

01 / 2005

Adenosine triphosphate induces activation of caspase-3 in apoptosis of human granulosa-luteal cells

Endocrine Journal

Tai, C.-J. and Chang, S.-J. and Chien, L.-Y. and Leung, P.C.K. and Tzeng, C.-R.

A randomized, double-blind, multicenter study comparing a starting dose of 100 IU or 200 IU of recombinant follicle stimulating hormone (Puregon) in women undergoing controlled ovarian hyperstimulation for IVF Treatment

Journal of Assisted Reproduction and Genetics

Tan, S.L. and Child, T.J. and Cheung, A.P. and Fluker, M.R. and Yuzpe, A. and Casper, R. and Leung, P. and Cadesky, K. and Davis, V.J.

Erratum: "Adenosine 5'-triphosphate activates nuclear translocation of mitogen-activated protein kinases leading to the induction of early growth response 1 and raf expression in human granulosa-luteal cells (The Journal of Clinical Endocrinology and Metabolism (2004) 89 (5189-5195))

Journal of Clinical Endocrinology and Metabolism

Tai, C.-J. and Chang, S.-J. and Leung, P.C.K. and Tzeng, C.-R.

Extrapituitary effects of GnRH and analogs: evidence and importance

Medicine Therapeutique en Endocrinologie de la Reproduction

7. Leung PC, Chen CL. Extrapituitary effects of GnRH and analogs: evidence and importance. Medicine Therapeutique en Endocrinologie de la Reproduction. 7:335-341 (2005).

Overexpression of Follicle-Stimulating Hormone Receptor Activates Oncogenic Pathways in Preneoplastic Ovarian Surface Epithelial Cells

The Journal of Clinical Endocrinology & Metabolism

Jung-Hye Choi and Kyung-Chul Choi and Nelly Auersperg and Peter C. K. Leung

11 / 2004

Adenosine 5'-Triphosphate Activates Nuclear Translocation of Mitogen-Activated Protein Kinases Leading to the Induction of Early Growth Response 1 and Raf Expression in Human Granulosa-Luteal Cells

The Journal of Clinical Endocrinology & Metabolism

Chen-Jei Tai and Shu-Ju Chang and Peter C. K. Leung and Chii-Ruey Tzeng

10 / 2004

Neutrophil apoptosis in preeclampsia, do steroids confound the relationship?

Journal of Obstetrics and Gynaecology Research

Akiko Fuchisawa and Stephan van Eeden and Laura A. Magee and Beth Whalen and Peter C. K. Leung and James A. Russell and Keith R. Walley and Peter von Dadelszen

10 / 2004

Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation.

Experimental cell research

09 / 2004

Caspase-1zeta, a new splice variant of the caspase-1 gene.

Genomics

09 / 2004

Transfer of maternally injected endocrine disruptors through breast milk during lactation induces neonatal Calbindin-D9k in the rat model

Reproductive Toxicology

Eui-Ju Hong and Kyung-Chul Choi and Yong-Woo Jung and Peter C.K Leung and Eui-Bae Jeung

07 / 2004

Activin Receptor Signaling

Growth Factors

06 / 2004

Type II Gonadotropin-Releasing Hormone Stimulates p38 Mitogen-Activated Protein Kinase and Apoptosis in Ovarian Cancer Cells

The Journal of Clinical Endocrinology & Metabolism

Ki-Yon Kim and Kyung-Chul Choi and Se-Hyung Park and Chun-Shan Chou and Nelly Auersperg and Peter C. K. Leung

06 / 2004

Mini ReviewActivin Receptor Signaling

Growth Factors

Yumiko Abe and Takashi Minegishi and Peter C.K. Leung

06 / 2004

Oviductal glycoprotein, a new differentiation-based indicator present in early ovarian epithelial neoplasia and cortical inclusion cysts.

Gynecologic oncology

05 / 2004

Effects of Epidermal Growth Factor/Hydrocortisone on the Growth and Differentiation of Human Ovarian Surface Epithelium

Journal of the Society for Gynecologic Investigation

Clara M. Salamanca and Sarah L. Maines-Bandiera and Peter C. K. Leung and Yu-Long Hu and Nelly Auersperg

05 / 2004

Epithelio-mesenchymal transition in a neoplastic ovarian epithelial hybrid cell line.

Differentiation; research in biological diversity

04 / 2004

Cellular Localization of Gonadotropin-Releasing Hormone (GnRH) I and GnRH II in First-Trimester Human Placenta and Decidua

The Journal of Clinical Endocrinology & Metabolism

Chun-Shan Chou and Alexander G. Beristain and Colin D. MacCalman and Peter C. K. Leung

03 / 2004

Complex regulation of Calbindin-D9k in the mouse placenta and extra-embryonic membrane during mid- and late pregnancy

Molecular and Cellular Endocrinology

Beum-Soo An and Kyung-Chul Choi and Geun-Shik Lee and Peter C.K. Leung and Eui-Bae Jeung

02 / 2004

Gain of OGP, an Estrogen-Regulated Oviduct-Specific Glycoprotein, Is Associated with the Development of Endometrial Hyperplasia and Endometrial Cancer

Clinical Cancer Research

M. M. M. Woo

Preface

The Ovary: Second Edition

Leung, P.C.K. and Adashi, E.Y.

Gn-RH as an Autocrine Regulator in the Human Ovary

The Ovary, Second Edition

Regulatory Effects of Gonadotropin-Releasing Hormone (GnRH) I and GnRH II on the Levels of Matrix Metalloproteinase (MMP)-2, MMP-9, and Tissue Inhibitor of Metalloproteinases-1 in Primary Cultures of Human Extravillous Cytotrophoblasts

The Journal of Clinical Endocrinology & Metabolism

Chun-Shan Chou and Hua Zhu and Colin D. MacCalman and Peter C. K. Leung

10 / 2003

Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium.

Reproductive biology and endocrinology : RB&E

10 / 2003

Differential Effects of Gonadotropin-Releasing Hormone I and II on the Urokinase-Type Plasminogen Activator/Plasminogen Activator Inhibitor System in Human Decidual Stromal Cellsin Vitro

The Journal of Clinical Endocrinology & Metabolism

Chun-Shan Chou and Colin D. MacCalman and Peter C. K. Leung

08 / 2003

Transcriptional regulation of the mouse calbindin-D9k gene by the ovarian sex hormone.

Molecules and cells

08 / 2003

Functional Cooperation between Multiple Regulatory Elements in the Untranslated Exon 1 Stimulates the Basal Transcription of the Human GnRH-II Gene

Molecular Endocrinology

Chi Keung Cheng and Ruby L. C. Hoo and Billy K. C. Chow and Peter C. K. Leung

07 / 2003

Potential role of gonadotrophin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer.

Endocrine-related cancer

06 / 2003

Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta.

Biology of reproduction

05 / 2003

Multi-factorial role of GnRH-I and GnRH-II in the human ovary

Molecular and Cellular Endocrinology

Peter C.K. Leung and Chi Keung Cheng and Xiao-Ming Zhu

04 / 2003

Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells.

Reproductive biology and endocrinology : RB&E

03 / 2003

Dose-Dependent Effects of Gonadotropin Releasing Hormone on Matrix Metalloproteinase (MMP)-2, and MMP-9 and Tissue Specific Inhibitor of Metalloproteinases-1 Messenger Ribonucleic Acid Levels in Human Decidual Stromal Cells in Vitro

The Journal of Clinical Endocrinology & Metabolism

02 / 2003

Gonadotropin-Releasing Hormone And Reproductive Medicine

Journal of Obstetrics and Gynaecology Canada

Eliezer Shalev and Peter C.K. Leung

02 / 2003

Two Inr Elements Are Important for Mediating the Activity of the Proximal Promoter of the Human Gonadotropin-Releasing Hormone Receptor Gene

Endocrinology

02 / 2003

Differential Regulation of Gonadotropin-Releasing Hormone (GnRH)I and GnRHII Messenger Ribonucleic Acid by Gonadal Steroids in Human Granulosa Luteal Cells

The Journal of Clinical Endocrinology & Metabolism

Shahram Khosravi and Peter C. K. Leung

02 / 2003

Adenosine triphosphate activates mitogen-activated protein kinase in pre-neoplastic and neoplastic ovarian surface epithelial cells.

Biology of reproduction

01 / 2003

Transcriptional regulation of the mouse calbindin-D9k gene by the ovarian sex hormone

Molecules and Cells

Lee, K.-Y. and Oh, G.T. and Kang, J.-H. and Shin, S.M. and Heo, B.-E. and Yun, Y.-W. and Paik, S.-G. and Krisinger, J. and Leung, P.C.K. and Jeung, E.-B.

The Ovary: Second Edition

The Ovary: Second Edition

Leung, P.C.K. and Adashi, E.Y.

Differential effects of cellular fibronectin and plasma fibronectin on ovarian cancer cell adhesion, migration, and invasion.

In vitro cellular & developmental biology. Animal

Oncogenic pathways of mitogen-activated protein kinases and phosphatidylinositol 3-kinase in epithelial ovarian cancer

Korean Journal of Gynecologic Oncology and Colposcopy

Jeung EB, Park SH, Leung PC, Yang HS, Sim JC, Kim KT, Choi KC. Oncogenic pathways of mitogen-activated protein kinases and phosphatidylinositol 3-kinase in epithelial ovarian cancer. Korean Journal of Gynecologic Oncology and Colposcopy. 14:290-299 (2003).

An Activator Protein 1-Like Motif Mediates 17-Estradiol Repression of Gonadotropin-Releasing Hormone Receptor Promoter via an Estrogen Receptor a-Dependent Mechanism in Ovarian and Breast Cancer Cells

Molecular Endocrinology

Chi Keung Cheng and Billy K. C. Chow and Peter C. K. Leung

Effects of gonadotropin-releasing hormone (GnRH)-I and -II on regulating the urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor (PAI-1) in cultured human extravillous cytotrophoblasts

Fertility and Sterility

Chunshan Sam Chou and Eliezer Shalev and Hua Ellen Zhu and Colin D MacCalman and Peter C.K Leung

09 / 2002

Adenosine triphosphate induces activation of caspase in apoptosis of human granulosa-luteal cells

Fertility and Sterility

Chen-Jei Tai and Shu-Ju Chang and Peter C.K Leung and Chii-Ruey Tzeng

09 / 2002

Human Chorionic Gonadotropin-Activated cAMP Pathway Regulates Human Placental GnRH Receptor Gene Transcription in Choriocarcinoma JEG-3 Cells

The Journal of Clinical Endocrinology & Metabolism

Kwai Wa Cheng and Peter C. K. Leung

07 / 2002

Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells.

Molecular Endocrinology

07 / 2002

Follicle-Stimulating Hormone Activates Mitogen-Activated Protein Kinase in Preneoplastic and Neoplastic Ovarian Surface Epithelial Cells

The Journal of Clinical Endocrinology & Metabolism

Kyung-Chul Choi and Sung Keun Kang and Chen-Jei Tai and Nelly Auersperg and Peter C. K. Leung

05 / 2002

Intracellular Calcium Mobilization in Response to the Activation of Human Wild-Type and Chimeric Gonadotropin Receptors

Endocrinology

Pearly S. N. Lee and Alison M. J. Buchan and Aaron J. W. Hsueh and Basil Ho Yuen and Peter C. K. Leung

05 / 2002

Characterization of a new upstream GnRH receptor promoter in human ovarian granulosa-luteal cells

Molecular Endocrinology

Cheng, C.K. and Yeung, C.M. and Chow, B.K.C. and Leung, P.C.K.

Oct-1 Is Involved in the Transcriptional Repression of the Gonadotropin-Releasing Hormone Receptor Gene

Endocrinology

Chi Keung Cheng and Chung Man Yeung and Ruby L. C. Hoo and Billy K. C. Chow and Peter C. K. Leung

The effects of gonadotropin-releasing hormone (GnRH) I and GnRH II on the urokinase-type plasminogen activator/plasminogen activator inhibitor system in human extravillous cytotrophoblasts in vitro

Journal of Clinical Endocrinology and Metabolism

Chou, C.-S. and Zhu, H. and Shalev, E. and MacCalman, C.D. and Leung, P.C.K.

Expression and Antiproliferative Effect of a Second Form of Gonadotropin-Releasing Hormone in Normal and Neoplastic Ovarian Surface Epithelial Cells

The Journal of Clinical Endocrinology & Metabolism

Kyung-Chul Choi and Nelly Auersperg and Peter C. K. Leung

10 / 2001

Direct Action of Melatonin in Human Granulosa-Luteal Cells

The Journal of Clinical Endocrinology & Metabolism

Michelle M. M. Woo and Chen-Jei Tai and Sung Keun Kang and Parimal S. Nathwani and Shiu Fun Pang and Peter C. K. Leung

10 / 2001

Profiling of Protein Kinases in the Neoplastic Transformation of Human Ovarian Surface Epithelium

Gynecologic Oncology

Alice S.T. Wong and Sung O. Kim and Peter C.K. Leung and Nelly Auersperg and Steven L. Pelech

08 / 2001

Human gonadotropin-releasing hormone receptor gene transcription: up-regulation by 3',5'-cyclic adenosine monophosphate/protein kinase A pathway

Molecular and Cellular Endocrinology

Kwai Wa Cheng and Peter C.K. Leung

07 / 2001

Antigonadotropic Action of Adenosine Triphosphate in Human Granulosa-Luteal Cells: Involvement of Protein Kinase Ca

The Journal of Clinical Endocrinology & Metabolism

07 / 2001

Estradiol up-regulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells.

Endocrinology

06 / 2001

Interplay of pituitary adenylate cyclase-activating polypeptide with a silencer element to regulate the upstream promoter of the human gonadotropin-releasing hormone receptor gene

Molecular and Cellular Endocrinology

Elly S.W. Ngan and Peter C.K. Leung and Billy K.C. Chow

05 / 2001

The Regulation of Apoptosis by Activin and Transforming Growth Factor- in Early Neoplastic and Tumorigenic Ovarian Surface Epithelium1

The Journal of Clinical Endocrinology & Metabolism

Kyung-Chul Choi and Sung Keun Kang and Chen-Jei Tai and Nelly Auersperg and Peter C. K. Leung

05 / 2001

Adenosine triphosphate activates mitogen-activated protein kinase in human granulosa-luteal cells.

Endocrinology

04 / 2001

Functional Mapping of a Placenta-Specific Upstream Promoter for Human Gonadotropin-Releasing Hormone Receptor Gene1

Endocrinology

Kwai Wa Cheng and Billy K. C. Chow and Peter C. K. Leung

04 / 2001

Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology

Endocrine Reviews

04 / 2001

Differential expression of activin/inhibin subunit and activin receptor mRNAs in normal and neoplastic ovarian surface epithelium (OSE)

Molecular and Cellular Endocrinology

Kyung-Chul Choi and Sung Keun Kang and Parimal S. Nathwani and Kwai Wa Cheng and Nelly Auersperg and Peter C.K. Leung

03 / 2001

Coexpression of hepatocyte growth factor-Met: an early step in ovarian carcinogenesis?

Oncogene

03 / 2001

Stimulation of Mitogen-Activated Protein Kinase by Gonadotropin-Releasing Hormone in Human Granulosa-Luteal Cells

Endocrinology

02 / 2001

Estradiol Regulates Gonadotropin-Releasing Hormone (GnRH) and its Receptor Gene Expression and Antagonizes the Growth Inhibitory Effects of GnRH in Human Ovarian Surface Epithelial and Ovarian Cancer Cells

Endocrinology

02 / 2001

Adenosine Triphosphate-Evoked Cytosolic Calcium Oscillations in Human Granulosa-Luteal Cells: Role of Protein Kinase C1

The Journal of Clinical Endocrinology & Metabolism

Chen-Jei Tai and Sung Keun Kang and Peter C. K. Leung

02 / 2001

Differential Regulation of Two Forms of Gonadotropin-Releasing Hormone Messenger Ribonucleic Acid in Human Granulosa-Luteal Cells

Endocrinology

01 / 2001

Role of Mitogen-Activated Protein Kinase in Prostaglandin F2aAction in Human Granulosa-Luteal Cells

The Journal of Clinical Endocrinology & Metabolism

01 / 2001

Adenosine triphosphate activates mitogen-activated protein kinase in human granulosa-luteal cells

Endocrinology

Tai, C.-J. and Sung Keun Kang and Tzeng, C.-R. and Leung, P.C.K.

Interaction of Prostaglandin F2aand Prostaglandin-E2on Progesterone Production in Human Granulosa-Luteal Cells

Neurosignals

Vnnen, J.E. and Tong, B.L.P. and Vnnen, C.C.M. and Chan, I.H.H. and Yuen, B.H. and Leung, P.C.K.

Functional mapping of a placenta-specific upstream promoter for human gonadotropin-releasing hormone receptor gene

Endocrinology

Kwai Wa Cheng and Chow, B.K.C. and Leung, P.C.K.

Detection of mRNA expression of gonadotropin-releasing hormone and its receptor in normal and neoplastic rat prostates

International Journal of Oncology

H. Lau and Xiao-Ming Zhu and Peter Leung and L. Chan and G. Chen and Peter Chan and K. Yu and Franky Chan

Interaction of prostaglandin F(2alpha) and prostaglandin E(2) on progesterone production in human granulosa-luteal cells.

Biological signals and receptors

Estradiol up-regulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells

Endocrinology

Choi, K.-C. and Kang, S.K. and Tai, C.-J. and Auersperg, N. and Leung, P.C.K.

Expression and anti-proliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells

Journal of Clinical Endocrinology and Metabolism

Choi, K.-C. and Auersperg, N. and Leung, P.C.K.

Adenosine triphosphate-evoked cytosolic calcium oscillations in human granulosa-luteal cells: Role of protein kinase C

Journal of Clinical Endocrinology and Metabolism

Tai, C.-J. and Kang, S.K. and Leung, P.C.K.

Role of mitogen-activated protein kinase in prostaglandin F2a action in human granulosa-luteal cells

Journal of Clinical Endocrinology and Metabolism

Tai, C.-J. and Kang, S.K. and Choi, K.-C. and Tzeng, C.-R. and Leung, P.C.K.

The regulation of apoptosis by activin and transforming growth factor- in early neoplastic and tumorigenic ovarian surface epithelium

Journal of Clinical Endocrinology and Metabolism

Choi, K.-C. and Kang, S.K. and Tai, C.-J. and Auersperg, N. and Leung, P.C.K.

Differentiation and growth potential of human ovarian surface epithelial cells expressing temperature sensitive SV40T antigen

In Vitro Cellular & Developmental Biology - Animal

Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene

Molecular Endocrinology

Cheng, K.W. and Cheng, C.-K. and Leung, P.C.K.

Transcriptional Down-Regulation of Human Gonadotropin-Releasing Hormone (GnRH) Receptor Gene by GnRH: Role of Protein Kinase C and Activating Protein 1

Endocrinology

10 / 2000

Hormonal Regulation of Estrogen Receptor a and Gene Expression in Human Granulosa-Luteal Cellsin Vitro

The Journal of Clinical Endocrinology & Metabolism

10 / 2000

Hepatocyte growth factor promotes in vitro scattering and morphogenesis of human cervical carcinoma cells.

Gynecologic oncology

08 / 2000

Regulation of Human Gonadotropin-Releasing Hormone Receptor Gene Expression in Placental Cells

Endocrinology

07 / 2000

Regulation of Gonadotropin-Releasing Hormone and Its Receptor Gene Expression by 17-Estradiol in Cultured Human Granulosa-Luteal Cells

Endocrinology

05 / 2000

Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells

Molecular and Cellular Endocrinology

Sung Keun Kang and Kwai Wa Cheng and Elly S.W. Ngan and Billy K.C. Chow and Kyung-Chul Choi and Peter C.K. Leung

04 / 2000

Presence of activin signal transduction in normal ovarian cells and epithelial ovarian carcinoma.

British journal of cancer

04 / 2000

Expression and Regulation of P2U-Purinergic Receptor in Human Granulosa-Luteal Cells1

The Journal of Clinical Endocrinology & Metabolism

Chen-Jei Tai and Sung Keun Kang and Kwai Wa Cheng and Kyung-Chul Choi and Parimal S. Nathwani and Peter C. K. Leung

04 / 2000

Expression and Regulation of P2U-Purinergic Receptor in Human Granulosa-Luteal Cells

The Journal of Clinical Endocrinology & Metabolism

04 / 2000

Identification of an Upstream Promoter in the Human Gonadotropin-Releasing Hormone Receptor Gene

Biochemical and Biophysical Research Communications

Elly S.W. Ngan and Peter C.K. Leung and Billy K.C. Chow

04 / 2000

Role of Gonadotropin-Releasing Hormone as an Autocrine Growth Factor in Human Ovarian Surface Epithelium

Endocrinology

01 / 2000

The expression, regulation and signal transduction pathways of the mammalian gonadotropin-releasing hormone receptor

Canadian Journal of Physiology and Pharmacology

Kwai Wa Cheng and Peter CK Leung

Autocrine Role of Gonadotropin-Releasing Hormone and Its Receptor in Ovarian Cancer Cell Growth

Endocrine

Sung K. Kang and Kwai W. Cheng and Parimal S. Nathwani and Kyung-Chul Choi and Peter C. K. Leung

Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells

Molecular and Cellular Endocrinology

Sung Keun Kang and Chen-Jei Tai and Kwai Wa Cheng and Peter C.K Leung

Extrapituitary gonadotropin-releasing hormone (GnRH) receptor

Hormone Frontier in Gynecology

Leung PC Kang SK. Extrapituitary gonadotropin-releasing hormone (GnRH) receptor. Hormone Frontier in Gynecology. 7:66-73 (2000).

Steroidogenic Factor-1 Interacts with a Gonadotrope-Specific Element within the First Exon of the Human Gonadotropin-Releasing Hormone Receptor Gene to Mediate Gonadotrope-Specific Expression

Endocrinology

06 / 1999

Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: Influence of family history of ovarian cancer

International Journal of Cancer

Alice S.T. Wong and Sarah L. Maines-Bandiera and Barry Rosen and Margaret J. Wheelock and Keith R. Johnson and Peter C.K. Leung and Calvin D. Roskelley and Nelly Auersperg

04 / 1999

Human ovary and placenta express messenger RNA for multiple activin receptors

Life Sciences

Chun Peng and Tsukasa Ohno and Loo Yee Koh and Victor T.S. Chen and Peter C.K. Leung

02 / 1999

Human Peripheral Blood Mononuclear Cells Express Gonadotropin-Releasing Hormone (GnRH), GnRH Receptor, and Interleukin-2 Receptor -Chain Messenger Ribonucleic Acids That Are Regulated by GnRHin Vitro

The Journal of Clinical Endocrinology & Metabolism

02 / 1999

Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 receptor -chain messenger ribonucleic acids that are regulated by GnRH in vitro

Journal of Clinical Endocrinology and Metabolism

Chen, H.-F. and Jeung, E.-B. and Stephenson, M. and Leung, P.C.K.

Cell survival effect of activin against heat shock stress on OVCAR3

Life Sciences

Jun Fukuda and Ikuro Ito and Toshinobu Tanaka and Peter C.K. Leung

11 / 1998

Metaplastic changes in cultured human ovarian surface epithelium.

In vitro cellular & developmental biology. Animal

10 / 1998

Regulation of prostaglandin F2alpha-receptor mRNA in human granulosa-luteal cells by human chorionic gonadotrophin and prostaglandin F2alpha.

Endocrine

06 / 1998

Stepwise activation of the gonadotropic signal transduction pathway, and the ability of prostaglandin F2alpha to inhibit this activated pathway.

Endocrine

06 / 1998

Expression of the messenger RNA for gonadotropin-releasing hormone and its receptor in human cancer cell lines

Life Sciences

Hong Yin and Kwai Wa Cheng and Hsiao-Lin Hwa and Chun Peng and Nelly Auersperg and Peter C.K. Leung

04 / 1998

Interaction of prostaglandin F2alpha and gonadotropin-releasing hormone on progesterone and estradiol production in human granulosa-luteal cells.

Biology of reproduction

12 / 1997

Efficient introduction of genes into human ovarian surface epithelium

In Vitro Cellular & Developmental Biology - Animal

Earnest H. Leung and Barry R. Davies and Peter C. K. Leung and George T. C. Chen and Calvin D. Roskelley and Nelly Auersperg

09 / 1997

Mechanisms involved in ATP-evoked Ca2+ oscillations in isolated human granulosa-luteal cells.

Cell calcium

05 / 1997

Characterization and regulation of a mRNA encoding the prostaglandin F2alpha receptor in the rat ovary.

Molecular and cellular endocrinology

10 / 1996

P2-purinoreceptor evoked changes in intracellular calcium oscillations in single isolated human granulosa-lutein cells.

Endocrinology

P S Lee and P E Squires and A M Buchan and B H Yuen and P C Leung

09 / 1996

Quantitation of activin receptor type-I mRNA by competitive PCR in human trophoblast cells

Placenta

Victor Chen and Jessica Dy and Chun Peng and Peter C.K. Leung

07 / 1996

Long-term growth and steroidogenic potential of human granulosa-lutein cells immortalized with SV40 large T antigen

Molecular and Cellular Endocrinology

Byong-Lyul Lie and Earnest Leung and Peter C.K. Leung and Nelly Auersperg

07 / 1996

Molecular characterisation of the gonadotropin-releasing hormone receptor gene

Animal Reproduction Science

Peter C.K. Leung and Nancy C. Fan and Chun Peng

04 / 1996

Gonadotropin-Releasing Hormone Receptor: Gene Structure, Expression and Regulation

Neurosignals

Peter C.K. Leung and Chun Peng

Prostaglandins and Their Receptors: Implications for Ovarian Physiology

Neurosignals

Jan I. Olofsson and Peter C.K. Leung

Hormone receptors and signaling in reproduction

NeuroSignals

Leung, P.C.K. and Kraicer, P.F.

Activin and Follistatin as Local Regulators in the Human Ovary

Neurosignals

Chun Peng and Tsukasa Ohno and Shideh Khorasheh and Peter C.K. Leung

Purinoreceptor-mediated calcium signalling in isolated human granulosa-lutein cells

Endocrinology

Lee PS, Squires PE, Buchan AM, Yuen BH, Leung PC. Purinoreceptor-mediated calcium signalling in isolated human granulosa-lutein cells. Endocrinology. 137:3756-3761 (1996).

Mapping of the gonadotropin-releasing hormone (GnRH) receptor gene to human chromosome 4q21.2 by fluorescence in situ hybridization.

Mammalian genome : official journal of the International Mammalian Genome Society

04 / 1995

The baboon expresses the calbindin-D9k gene in intestine but not in uterus and placenta: Implication for conservation of the gene in primates

Molecular Reproduction and Development

Eui-Bae Jeung and Nancy C. Fan and Peter C. K. Leung and John C. Herr and Alex Freemerman and John Krisinger

04 / 1995

Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells.

Endocrinology

J I Olofsson and C C Conti and P C Leung

03 / 1995

The human gonadotropin-releasing hormone receptor gene: complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals

Molecular and Cellular Endocrinology

Nancy C Fan and Chun Peng and John Krisinger and Peter C.K Leung

02 / 1995

Porcine Calbindin-D9k Gene: Expression in Endometrium, Myometrium, and Placenta in the Absence of a Functional Estrogen Response Element in Intron A

Biology of Reproduction

01 / 1995

Expression and regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor messenger ribonucleic acids in human granulosa-luteal cells.

Endocrinology

11 / 1994

The human gonadotropin-releasing hormone (GnRH) receptor gene: cloning, genomic organization and chromosomal assignment.

Molecular and cellular endocrinology

07 / 1994

Expression of calbindin-D9k in the early pregnant rat uterus: Effects of RU 486 and correlation to estrogen receptor mRNA

Molecular and Cellular Endocrinology

John Krisinger and Takuya Setoyama and Peter C.K. Leung

06 / 1994

Auto/paracrine role of prostaglandins in corpus luteum function

Molecular and Cellular Endocrinology

Jan Olofsson and Peter C.K. Leung

04 / 1994

Gonadotropin-releasing hormone (GnRH) and cyclic amp positively regulate inhibin subunit messenger RNA levels in human placental cells

Life Sciences

Wei Li and Jan I. Olofsson and Eui-Bae Jeung and John Krisinger and Basil Ho Yuen and Peter C.K. Leung

01 / 1994

The Human Calbindin-D9k Gene

Journal of Molecular Biology

Eui-Bae Jeung and Peter C.K. Leung and John Krisinger

01 / 1994

Tissue-specific regulation of gonadotropin-releasing hormone (GnRH) receptor gene expression during the periovulatory period

Endocrine

Olofsson JI, Conti CC, Leung C, Krisinger J, Leung PC. Tissue-specific regulation of gonadotropin-releasing hormone (GnRH) receptor gene expression during the periovulatory period. Endocrine. 2:471-476 (1994).

Expression of the type II activin receptor gene in the human placenta.

Endocrinology

12 / 1993

Cytosolic free Ca2+ in human syncytiotrophoblast cells increased by gonadotropin-releasing hormone

Endocrinology

W. D. Currie

11 / 1993

Calbindin-D9k gene expression during the perinatal period in the rat: correlation to estrogen receptor expression in uterus

Molecular and Cellular Endocrinology

John Krisinger and Jamie L. Dann and Oliver Applegarth and W.David Currie and Eui-Bae Jeung and Michael Staun and Peter C.K. Leung

11 / 1993

Acute stimulation of human chorionic gonadotropin secretion by recombinant human activin-A in first trimester human trophoblast.

Endocrinology

07 / 1993

Stimulation of progesterone secretion by recombinant follistatin-288 in human granulosa cells.

Endocrinology

04 / 1993

Arachidonic acid and cell signalling in the ovary and placenta.

Prostaglandins, leukotrienes, and essential fatty acids

01 / 1993

Characterization of Cell Types within a Chorionic Gonadotropin-Secreting, Mechanically Dissociated Human Placental Cell Population in Perifusion

Neurosignals

Gillian L. Steele and David Currie and Basil Ho Yuen and Peter C.K. Leung

Expression of the type II activin receptor gene in the human placenta

Endocrinology

Peng, C. and Jackson Huang, T.-H. and Jeung, E.-B. and Donaldson, C.J. and Vale, W.W. and Leung, P.C.K.

Signal Transduction of PGF2a in Rat Corpora Lutea

Molecular Basis of Reproductive Endocrinology

Gillian L. Steele and Peter C. K. Leung

Arachidonic Acid as a Second Messenger for Regulation of Aromatase Activity in Porcine Granulosa Cells

Molecular Basis of Reproductive Endocrinology

F. Ledwitz-Rigby and M. K. Nickerson and S. W. Lin and Peter C. K. Leung

Acute stimulation of human chorionic gonadotropin secretion by recombinant human activin-A in first trimester human trophoblast

Endocrinology

Steele, G.L. and Currie, W.D. and Yuen, B.H. and Jia, X.-C. and Perlas, E. and Leung, P.C.K.

GnRH- and cAMP-Stimulated Human Chorionic Gonadotropin Secretion from Perifused Placental Cells

Molecular Basis of Reproductive Endocrinology

W. David Currie and Gillian L. Steele and Basil Ho-Yuen and Peter C. K. Leung

Mechanism of prostaglandin F2 alpha action in the ovary.

Journal of lipid mediators

LHRH- and (Hydroxyproline9) LHRH-Stimulated hCG Secretion from Perifused First-Trimester Placental Cells

Recent Progress in Hormone Research

W. DAVID CURRIE and GILLIAN L. STEELE and BASIL HO YUEN and CLAUDE KORDON and J.-PIERRE GAUTRON and Peter C.K. Leung

Molecular Basis of Reproductive Endocrinology

Peter C. K. Leung and Aaron J. W. Hsueh and Henry G. Friesen

LHRH- and (hydroxyproline9) LHRH-stimulated hCG secretion from perifused first-trimester placental cells.

Recent progress in hormone research

Divergent differentiation of rat adrenocortical cells is associated with an interruption of angiotensin II-mediated signal transduction

Molecular and Cellular Endocrinology

Calvin D Roskelley and Kenneth G Baimbridge and Peter C.K Leung and Nelly Auersperg

11 / 1992

Cloning of the Porcine Calbindin-D9k Complementary Deoxyribonucleic Acid by Anchored Polymerase Chain Reaction Technique1

Biology of Reproduction

Eui-Bae Jeung and John Krisinger and Jamie L. Dann and Peter C. K. Leung

10 / 1992

Calbindin-D9k gene expression during pregnancy and lactation in the rat

Molecular and Cellular Endocrinology

J. Krisinger and J.L. Dann and E.B. Jeung and P.C.K. Leung

10 / 1992

Rapid stimulation of human chorionic gonadotropin secretion by interleukin-1 beta from perifused first trimester trophoblast.

The Journal of Clinical Endocrinology & Metabolism

G L Steele and W D Currie and E H Leung and B H Yuen and P C Leung

09 / 1992

Intracellular calcium and the signaling mechanism of luteinizing hormone"releasing hormone in rat granulosa cells

American Journal of Obstetrics and Gynecology

Jian Wang and Gillian L. Steele and Kenneth G. Baimbridge and Marie R. Rodway and Peter C.K. Leung

08 / 1992

Intracellular signaling in the gonads.

Endocrine reviews

08 / 1992

Calbindin-D9k mRNA is tightly regulated during the estrous cycle in the rat uterus.

Molecular and cellular endocrinology

07 / 1992

Molecular cloning of the full-length cDNA encoding the human calbindin-D9k

FEBS Letters

Eui-Bae Jeung and John Krisinger and Jamie L. Dann and Peter C.K. Leung

07 / 1992

Inhibition of progestin accumulation by activin-A in human granulosa cells.

The Journal of clinical endocrinology and metabolism

07 / 1992

Cytosolic free calcium increased by prostaglandin F2 alpha (PGF2 alpha), gonadotropin-releasing hormone, and angiotensin II in rat granulosa cells and PGF2 alpha in human granulosa cells.

Endocrinology

04 / 1992

Prostaglandin F2a and gonadotropin-releasing hormone increase intracellular free calcium in rat granulosa cells

Molecular and Cellular Endocrinology

Marie R. Rodway and Gillian L. Steele and Kenneth G. Baimbridge and Peter C.K. Leung

03 / 1992

Intragonadal signalling mechanisms in the control of steroid hormone production

The Journal of Steroid Biochemistry and Molecular Biology

Gillian L. Steele and Peter C.K. Leung

03 / 1992

Inhibition of progestin accumulation by activin-A in human granulosa cells

Journal of Clinical Endocrinology and Metabolism

Li, W. and Yuen, B.H. and Leung, P.C.K.

Cytosolic free calcium increased by prostaglandin F2a (PGF2a), gonadotropin-releasing hormone, and angiotensin II in rat granulosa cells and PGF2a in human granulosa cells

Endocrinology

Currie, W.D. and Li, W. and Baimbridge, K.G. and Yuen, B.H. and Leung, P.C.K.

Mechanism of prostaglandin F(2a) action in the ovary

Journal of Lipid Mediators

Steele, G.L. and Leung, P.C.K.

Rapid stimulation of human chorionic gonadotropin secretion by interleukin-1 from perifused first trimester trophoblast

Journal of Clinical Endocrinology and Metabolism

Steele, G.L. and Currie, W.D. and Leung, E.H. and Yuen, B.H. and Leung, P.C.K.

Intracellular signaling in the gonads

Endocrine Reviews

Leung, P.C.K. and Steele, G.L.

Luteinizing Hormone-Releasing Hormone (LHRH)- and (Hydroxyproline9)LHRH-stimulated human chorionic gonadotropin secretion from perifused first trimester placental cells

Endocrinology

Currie, W.D. and Steele, G.L. and Yuen, B.H. and Kordon, C. and Gautron, J.-P. and Leung, P.C.K.

Suppression of Luteinizing Hormone Secretion by Atrial and Brain Natriuretic Peptides in Ovariectomized Rats

Endocrinology

08 / 1991

Effect of prostaglandin F2 alpha on cytosolic free calcium ion concentrations in rat luteal cells.

Endocrinology

08 / 1991

Inositol Lipid Metabolism and Calcium Signaling in Rat Ovarian Cells

Signaling Mechanisms and Gene Expression in the Ovary

Marie R. Rodway and Peter C. K. Leung

Effect of prostaglandin F2a on cytosolic free calcium ion concentrations in rat luteal cells

Endocrinology

Rodway, M.R. and Baimbridge, K.G. and Yuen, B.H. and Leung, P.C.K.

Androgens Positively Regulate Follicle-Stimulating Hormone -Subunit mRNA Levels in Rat Pituitary Cells

Molecular Endocrinology

Soheyla D. Gharib and Peter C. K. Leung and Rona S. Carroll and William W. Chin

11 / 1990

Inhibition of aromatase activity by 8-bromo-cyclic adenosine monophosphate in cultured first-trimester human trophoblast

American Journal of Obstetrics and Gynecology

Marie R Rodway and Basil Ho Yuen and Peter C.K Leung

11 / 1990

The physiological basis of superovulation

Seminars in Reproductive Physiology

Armstrong DT, Leung PC. The physiological basis of superovulation. Seminars in Reproductive Physiology. 8:219-231, (1990).

Mechanism of action of luteinizing hormone-releasing hormone in rat ovarian cells

Canadian Journal of Physiology and Pharmacology

Peter C. K. Leung and Jian Wang and Kenneth G. Baimbridge

08 / 1989

Ovarian follicular development and regression

Canadian Journal of Physiology and Pharmacology

Peter C. K. Leung

08 / 1989

Synergistic stimulation of prostaglandin E2 production by calcium ionophore and protein kinase C activator in rat granulosa cells.

Biology of reproduction

05 / 1989

Arachidonic Acid as a Stimulatory Mediator of Luteinizing Hormone-Releasing Hormone Action in the Rat Ovary

Endocrinology

04 / 1989

Differential role of protein kinase C in the action of luteinizing hormone-releasing hormone on hormone production in rat ovarian cells

American Journal of Obstetrics and Gynecology

J. Wang and V. Lee and P.C.K. Leung

04 / 1989

The Role of Inositol Lipid Metabolism in the Ovary

Biology of Reproduction

Peter C. K Leung and Jian Wang

04 / 1989

Changes in Cytosolic Free Calcium Ion Concentrations in Individual Rat Granulosa Cells: Effect of Luteinizing Hormone-Releasing Hormone*

Endocrinology

JIAN WANG and KENNETH G. BAIMBRIDGE and PETER C. K. LEUNG

04 / 1989

Perturbation of intracellular calcium ion concentration in single Rat Granulosa Cells by Angiotensin II

Endocrinology

02 / 1989

Stimulation of progesterone and prostaglandin E2 production by lipoxygenase metabolites of arachidonic acid.

FEBS letters

02 / 1989

Role of Calcium in the Action of LHRH on Ovarian Progesterone Production

Growth Factors and the Ovary

Peter C. K. Leung and Jian Wang

Synergistic stimulation of prostaglandin E2 production by calcium ionophore and protein kinase C activator in rat granulosa cells

Biology of Reproduction

Wang, J. and Leung, P.C.K.

A randomized study of high-dose versus low-dose cis-platinum combined with cyclophosphamide in the treatment of advanced ovarian cancer

Chemotherapy

Ngan, H.Y.S. and Choo, Y.C. and Cheung, M. and Wong, L.C. and Ma, H.K. and Collins, R. and Fung, C. and Ng, C.S. and Wong, V. and Ho, H.C. and Leung, P. and Wong, R. and Chan, E. and Simon, M.T.P. and Ho, L.C. and Chan, Y.F.

Inositol lipids and LHRH action in the rat ovary.

Journal of reproduction and fertility. Supplement

Effects of cyclic adenosine monophosphate on Human chorionic gonadotropin and Ostradiol output by cultured Human placental cells,Einfluss von zyklischem Adenosinmonophosphat auf die Freisetzung von humanem Choriongonadotropin und stradiol aus kultivierten humanen Plazentazellen

Gynakologisch-geburtshilfliche Rundschau

Benoit, J. and Rodway, M. and Yuen, B.H. and Leung, P.C.K.

Electrical Stimulation of Ascending Noradrenergic Tracts in the Midbrain: Suppression of Steroid-Induced Luteinizing Hormone Release

Endocrinology

03 / 1988

Role of Arachidonic Acid in Luteinizing Hormone-Releasing Hormone Action: Stimulation of Progesterone Production in Rat Granulosa Cells*

Endocrinology

JIAN WANG and PETER C. K. LEUNG

03 / 1988

Inhibition of follicle-stimulating hormone- and adenosine-3',5'-cyclic monophosphate-induced progesterone production by calcium and protein kinase C in the rat ovary.

American journal of obstetrics and gynecology

02 / 1988

Differential effects of 8-bromo-cyclic AMP on human chorionic gonadotropin (hCG), progesterone and estrogen production by term placental cells

Life Sciences

Marie Rodway and Fuzhen Zhou and Joanne Benoit and Basil Ho Yuen and Peter C.K. Leung

01 / 1988

Effects of cyclic adenosine monophosphate on human chorionic gonadotropin and estradiol output by cultured human placental cells

American Journal of Obstetrics and Gynecology

Joanne Benoit and Marie Rodway and Basil Ho Yuen and Peter C.K. Leung

Role of testosterone in the regulation of rat ovarian estradiol-17b secretion

Life Science Advances

Katz Y, Leung PC, Armstrong DT. Role of testosterone in the regulation of rat ovarian estradiol-17b secretion. Life Sci. Adv. 7:157 -159 (1988).

Inhibition of follicle-stimulating hormone- and adenosine-3, 5-cyclic monophosphate-induced progesterone production by calcium and protein kinase C in the rat ovary

Obstetrical and Gynecological Survey

Leung, P.C.K. and Minegishi, T. and Wang, J.

Role of protein kinase C in luteinizing hormone-releasing hormone (LHRH)-stimulated progesterone production in rat granulosa cells

Biochemical and Biophysical Research Communications

Jian Wang and Peter C.K. Leung

08 / 1987

Luteinizing hormone-releasing hormone (LHRH)-induced arachidonic acid release in rat granulosa cells Role of calcium and protein kinase C

FEBS Letters

T. Minegishi and J. Wang and P.C.K. Leung

04 / 1987

Effects of adenosine 3',5'-cyclic monophosphate, forskolin, and cholera toxin on hormone production in human term placental cells.

American journal of obstetrics and gynecology

02 / 1987

Dual Action of Norepinephrine in the Control of Gonadotropin Release

Endocrinology and Physiology of Reproduction

Hugo Bergen and Peter C. K. Leung

Electrical Stimulation of Ventral versus Dorsal Mesencephalic Tegmental Areas in the Conscious Rat: Effects on Luteinizing Hormone Release

Neuroendocrinology

Hugo Bergen and Peter C.K. Leung

Induction of Polyphosphoinositide Breakdown in Rat Corpus Luteum by Prostaglandin F2a

Endocrinology

07 / 1986

Norepinephrine inhibition of pulsatile LH release: receptor specificity.

The American journal of physiology

02 / 1986

Alleviation of Estrogen-Induced Hyperprolactinemia through Intracerebral Transplantation of Hypothalamic Tissue Containing Dopaminergic Neurons

Neuroendocrinology

Gary W. Arendash and Peter C.K. Leung

Relationship of gonadotropin-releasing hormone, danazol, and prostaglandin blockade to ovarian enlargement and ascites formation of the ovarian hyperstimulation syndrome in the rabbit

American Journal of Obstetrics and Gynecology

Pride, S.M. and Ho Yuen, B. and Moon, Y.S. and Leung, P.C.S.

Suppression of Progesterone-Induced Gonadotropin Surge by Adrenergic Agonists in Estrogen-Primed Ovariectomized Rats

Neuroendocrinology

Hugo Bergen and Peter C.K. Leung

Norepinephrine inhibition of pulsatile LH release: Receptor specificity

American Journal of Physiology - Endocrinology and Metabolism

Bergen, H. and Leung, P.C.K.

Luteinizing Hormone-Releasing Hormone Stimulates Arachidonic Acid Release in Rat Granulosa Cells

Endocrinology

11 / 1985

Effects of cannabinoids on progesterone release in cultures of rat luteal cells

Life Sciences

Peter C.K. Leung and Michael Flesher and Young S. Moon and Takashi Minegishi

11 / 1985

Luteinizing hormone-releasing hormone enhances polyphosphoinositide breakdown in rat granulosa cells

Biochemical and Biophysical Research Communications

Felix Ma and Peter C.K. Leung

08 / 1985

Effects of prostaglandins and luteinizing hormone-releasing hormone on phosphatidic acid " phosphatidylinositol labeling in rat granulosa cells

Canadian Journal of Physiology and Pharmacology

Takashi Minegishi and Peter C. K. Leung

04 / 1985

Mechanisms of gonadotropin-releasing hormone and prostaglandin action on luteal cells

Canadian Journal of Physiology and Pharmacology

Peter C. K. Leung

03 / 1985

Vasopressin rapidly stimulates phosphatidic acid-phosphatidylinositol turnover in rat anterior pituitary cells.

FEBS letters

03 / 1985

LHRH rapidly stimulates phosphatidylinositol metabolism in enriched gonadotrophs

Molecular and Cellular Endocrinology

Vincent Raymond and Peter C.K. Leung and Raymonde Veilleux and Grard Lefvre and Fernand Labrie

07 / 1984

Stimulation by prostaglandin F2 alpha of phosphatidic acid-phosphatidylinositol turnover in rat luteal cells.

Biochemical and biophysical research communications

10 / 1983

Androgenic alteration in pathways of C19-steroid metabolism by cultured rat granulosa cells.

Biochemical and biophysical research communications

06 / 1983

Stimulation of phosphatidic acid and phosphtidylinositol labeling in luteal cells by luteinizing hormone releasing hormone

Endocrinology

03 / 1983

Effect of prolactin in an experimental model of the ovarian hyperstimulation syndrome

American Journal of Obstetrics and Gynecology

Leung, P. and Yuen, B.H. and Moon, Y.S.

Role of norepinephrine in seizurelike activity of hippocampal pyramid cells maintained in vitro: Alteration by 6-hydroxydopamine lesions of norepinephrine-containing systems

Canadian Journal of Physiology and Pharmacology

Mody, I. and Leung, P. and Miller, J.J.

Mechanism of action of TRH: involvement of the phosphatidylinositol (PI) response in the action of TRH in rat anterior pituitary cells.

Life sciences

12 / 1982

Differential effects of central adrenoceptor agonists on luteinizing hormone release.

Neuroendocrinology

03 / 1982

Electrophysiologic correlates of steroid modulation of luteinizing hormone release.

The American journal of physiology

03 / 1982

beta-Adrenergic suppression of progesterone-induced luteinizing hormone surge in ovariectomized, estrogen-primed rats.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

02 / 1982

Electrophysiologic correlates of steroid modulation of luteinizing hormone release

American Journal of Physiology - Endocrinology and Metabolism

Leung, P.C.K. and Whitmoyer, D.I. and Sawyer, C.H.

-Adrenergic Suppression of Progesterone-Induced Luteinizing Hormone Surge in Ovariectomized, Estrogen-Primed Rats (41326)

Proceedings of the Society for Experimental Biology and Medicine

Leung, P.C.K. and Whitmoyer, D.I. and Garland, K.E. and Sawyer, C.H.

Metabolism of testosterone by human granulosa cells in culture: Influence of follicle-stimulating hormone and luteinizing hormone

American Journal of Obstetrics and Gynecology

Moon, Y.S. and Duleba, A. and Leung, P.C.S. and Gomel, V.

Effect of an aromatase inhibitor (4-acetoxy-4-androstene-3,17-dione) on the stimulatory action of luteinizing hormone on estradiol-17 beta synthesis by rat preovulatory follicles in vitro.

Biology of reproduction

09 / 1981

Electrical Stimulation of Mesencephalic Noradrenergic Pathway: Effects on Luteinizing Hormone Levels in Blood of Ovariectomized and Ovariectomized, Steroid-Primed Rats

Endocrinology

09 / 1981

Effects of intraventricular infusion of a- and -adrenoceptor agonists on blood levels of luteinizing hormone (LH) in ovariectomized (OVX) and OVX steroid-primed rats

Anatomical Record

Leung, P.C.K. and Arendash, G.W. and Whitmoyer, D.I.

Prostaglandin F in human endometriotic tissue

American Journal of Obstetrics and Gynecology

Moon, Y.S. and Leung, P.C.S. and Ho Yuen, B. and Gomel, V.

Norepinephrine-induced changes in multiunit electrical activity (MUA) of rostral diencephalon and mediobasal hypothalamus: Neural substrate for steroidal modulation of LH release?

Biology of Reproduction

Leung, P.C.K. and Whitmoyer, D.I. and Sawyer, C.H.

Effect of bromocriptine and prolactin on the ovarian response to exogenous gonadotropins

Fertility and Sterility

Ho Yuen, B. and Leung, P. and Moon, Y.S.

Effects of intraventricular norepinephrine on preoptic-anterior hypothalamic electrical activity in the freely-moving rat: modulation by ovarian steroid hormones

Brain Research

Peter C.K. Leung and David I. Whitmoyer and Gary W. Arendash and Charles H. Sawyer

Further evidence in support of a short-loop feedback action of estrogen on ovarian androgen production

Life Sciences

Peter C.K. Leung and David T. Armstrong

08 / 1980

Interactions of steroids and gonadotropins in the control of steroidogenesis in the ovarian follicle.

Annual review of physiology

Effect of mesencephalic electrical stimulation on blood luteinizing hormone (LH) levels in ovariectomized (OVX) and OVX, steroid-primed rats

Biology of Reproduction

Leung, P.C.K. and Arendash, G.W. and Gorski, R.A. and Sawyer, C.H.

A Mechanism for the Intraovarian Inhibitory Action of Estrogen on Androgen Production1

Biology of Reproduction

Peter C. K. Leung and David T. Armstrong

11 / 1979

Estrogen Treatment of Immature Rats Inhibits Ovarian Androgen Production in Vitro

Endocrinology

05 / 1979

Inhibition by estradiol-17 beta of porcine thecal androgen production in vitro.

Molecular and cellular endocrinology

05 / 1979

Interactions of Estrogen and Androgen with Gonadotropins on Ovarian Progesterone Production1

Biology of Reproduction

Peter C. K. Leung and Keith M. Henderson and David T. Armstrong

05 / 1979

Stimulatory action of androgen administration in vivo on ovarian responsiveness to gonadotropins.

Endocrinology

04 / 1979

Stimulatory action of follicle-stimulating hormone and androgens on the responsiveness of rat granulosa cells to gonadotropins in vitro.

Endocrinology

04 / 1979

Testosterone restores ovarian aromatase activity in rats treated with a 17,20-lyase inhibitor

Molecular and Cellular Endocrinology

Yair Katz and Peter C.K. Leung and David T. Armstrong

04 / 1979

Estrogen inhibits porcine thecal androgen production in vitro.

Advances in experimental medicine and biology

Leung, P.C. and Tsang, B.K. and Armstrong, D.T.

Changes with age in aromatization of testosterone in immature female rats.

Biology of reproduction

12 / 1978

An intraovarian inhibitory action of estrogen on androgen production in vivo.

Biology of reproduction

10 / 1978

Uterotrophic effects of testosterone and 5alpha-dihydrotestosterone in intact and ovariectomized immature female rats.

Biology of reproduction

08 / 1976

The thyroidal response to chronic goitrogenic stimulation and the persistence of effects of early goitrogenic stimulation

Canadian Journal of Physiology and Pharmacology

Peter Leung and B. E. March

08 / 1976

Effects of alterations in maternal thyroid metabolism on embryonic thyroid development in the chick

Canadian Journal of Physiology and Pharmacology

B. E. March and Peter Leung

06 / 1976

Potential Role of Gonadotropin-Releasing Hormone and Estrogen in Ovarian Cancer

Hormonal Carcinogenesis IV

Peter C. K. Leung and Kyung-Chul Choi and Nelly Auersperg