Overview

I work with patients with medical complications in pregnancy, but specifically in the area of Venous Thromboembolism in Pregnancy.

Publications

Diagnosis of venous thromboembolism in pregnancy
Thrombosis Research
Wee-Shian Chan
DOI: 10.1016/j.thromres.2017.09.003
09/2017

Maternal age and severe maternal morbidity: A population-based retrospective cohort study
PLOS Medicine
Sarka Lisonkova and Jayson Potts and Giulia M. Muraca and Neda Razaz and Yasser Sabr and Wee-Shian Chan and Michael S. Kramer
DOI: 10.1371/journal.pmed.1002307
05/2017

Low-molecular-weight heparin to prevent postpartum venous thromboembolism. A pilot randomised placebo-controlled trial
Thrombosis and Haematosis
PubMed: 25373438
01/2015

Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial
The Lancet
Marc A Rodger and William M Hague and John Kingdom and Susan R Kahn and Alan Karovitch and Mathew Sermer and Anne Marie Clement and Suzette Coat and Wee Shian Chan and Joanne Said and Evelyne Rey and Sue Robinson and Rshmi Khurana and Christine Demers and Michael J Kovacs and Susan Solymoss and Kim Hinshaw and James Dwyer and Graeme Smith and Sarah McDonald and Jill Newstead-Angel and Anne McLeod and Meena Khandelwal and Robert M Silver and Gregoire Le Gal and Ian A Greer and Erin Keely and Karen Rosene-Montella and Mark Walker and Philip S Wells
DOI: 10.1016/s0140-6736(14)60793-5
11/2014

When should we use diagnostic imaging to investigate for pulmonary embolism in pregnant and postpartum women?
Emergency Medicine Journal
Steve Goodacre and Catherine Nelson-Piercy and Beverley Hunt and Wee-Shian Chan
DOI: 10.1136/emermed-2014-203871
07/2014

Venous Thromboembolism and Antithrombotic Therapy in Pregnancy
Journal of Obstetrics and Gynaecology Canada
Wee-Shian Chan and Evelyne Rey and Nancy E. Kent and Wee-Shian Chan and Nancy E. Kent and Evelyne Rey and Thomas Corbett and Michèle David and M. Joanne Douglas and Paul S. Gibson and Laura Magee and Marc Rodger and Reginald E. Smith
DOI: 10.1016/s1701-2163(15)30569-7
06/2014

Multidisciplinary meeting of minds
Obstetric Medicine
Wee-Shian Chan and Jayson Potts and Lucille Wilkinson
DOI: 10.1177/1753495x14534572
05/2014

Focused 2012 Update of the Canadian Cardiovascular Society Guidelines for the Use of Antiplatelet Therapy
Canadian Journal of Cardiology
Jean-François Tanguay and Alan D. Bell and Margaret L. Ackman and Robert D.C. Bauer and Raymond Cartier and Wee-Shian Chan and James Douketis and André Roussin and Gregory Schnell and Subodh Verma and Graham Wong and Shamir R. Mehta
DOI: 10.1016/j.cjca.2013.07.001
11/2013

Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imaging
Canadian Medical Association Journal
W.-S. Chan and F. A. Spencer and A. Y. Y. Lee and S. Chunilal and J. D. Douketis and M. Rodger and J. S. Ginsberg
DOI: 10.1503/cmaj.120895
01/2013

Critical Illness in Obstetric Patients: Venous Thromboembolism in Pregnancy
Current Women's Health Reviews
Sanjeev Daya Chunilal and Wee Shian Chan
DOI: 10.2174/157340411795445749
05/2011

The Use of Antiplatelet Therapy in the Outpatient Setting: Canadian Cardiovascular Society Guidelines
Canadian Journal of Cardiology
Alan D. Bell and André Roussin and Raymond Cartier and Wee Shian Chan and James D. Douketis and Anil Gupta and Maria E. Kraw and Thomas F. Lindsay and Michael P. Love and Neesh Pannu and Rémi Rabasa-Lhoret and Ashfaq Shuaib and Philip Teal and Pierre Théroux and Alexander G.G. Turpie and Robert C. Welsh and Jean-François Tanguay
DOI: 10.1016/j.cjca.2010.12.015
05/2011

The Use of Antiplatelet Therapy in the Outpatient Setting: Canadian Cardiovascular Society Guidelines Executive Summary
Canadian Journal of Cardiology
Alan D. Bell and André Roussin and Raymond Cartier and Wee Shian Chan and James D. Douketis and Anil Gupta and Maria E. Kraw and Thomas F. Lindsay and Michael P. Love and Neesh Pannu and Rémi Rabasa-Lhoret and Ashfaq Shuaib and Philip Teal and Pierre Théroux and A. Graham Turpie and Robert C. Welsh and Jean-François Tanguay
DOI: 10.1016/j.cjca.2010.12.033
03/2011

Maternal mortality and severe maternal morbidity surveillance in Canada
Journal of Obstetrics and Gynaecology Canada
PubMed: 21176325
12/2010

Anatomic Distribution of Deep Vein Thrombosis in Pregnancy
Obstetrical & Gynecological Survey
Wee-Shian Chan and Frederick A. Spencer and Jeffrey S. Ginsberg
DOI: 10.1097/ogx.0b013e3182021d71
09/2010

Neurocognitive Development of Children Following In-Utero Exposure to Labetalol for Maternal Hypertension: A Cohort Study Using a Prospectively Collected Database
Hypertension in Pregnancy
Wee Shian Chan and Gideon Koren and Maru Barrera and Massoud Rezvani and Dafna Knittel-Keren and Irena Nulman
DOI: 10.3109/10641950902777705
07/2010

Prediction Rules Must Be Developed According to Methodological Guidelines
Annals of Internal Medicine
Wee-Shian Chan
DOI: 10.7326/0003-4819-152-4-201002160-00015
02/2010

D-dimer testing in pregnant patients: towards determining the next “level” in the diagnosis of DVT
Journal of Thrombosis and Haemostasis
W.-S. Chan and A. Lee and F. A. Spencer and S. Chunilal and M. Crowther and W. Wu and M. Johnston and M. Rodger and J. S. Ginsberg
DOI: 10.1111/j.1538-7836.2010.03783.x
01/2010

Venous thromboembolism in pregnancy
Expert Review of Cardiovascular Therapy
Wee Shian Chan
DOI: 10.1586/erc.10.169
2010

The ‘ART’ of thrombosis: a review of arterial and venous thrombosis in assisted reproductive technology
Current Opinion in Obstetrics and Gynecology
Wee Shian Chan
DOI: 10.1097/gco.0b013e328329c2b8
06/2009

Management of Venous Thromboembolism in Pregnancy
Deep Vein Thrombosis and Pulmonary Embolism
Wee Shian Chan and Jeffrey S. Ginsberg
DOI: 10.1002/9780470745007.ch16
04/2009

Management of Venous Thromboembolism in Pregnancy
Evidence-Based Hematology
Wee-Shian Chan
DOI: 10.1002/9781444300857.ch13
02/2009

Predicting Deep Venous Thrombosis in Pregnancy: Out in “LEFt” Field?
Obstetrical & Gynecological Survey
Wee-Shian Chan and Agnes Lee and Frederick A. Spencer and Mark Crowther and Marc Rodger and Tim Ramsay and Jeffrey S. Ginsberg
DOI: 10.1097/01.ogx.0000363248.09415.51
2009

Diagnosis of venous thromboembolism in pregnancy: a study in extrapolation or a science in evolution?
Expert Review of Cardiovascular Therapy
Wee-Shian Chan and Jeffrey S Ginsberg
DOI: 10.1586/erc.09.136
2009

Intrahepatic Cholestasis of Pregnancy in Women With a Multiple Pregnancy: An Analysis of Risks and Pregnancy Outcomes
Journal of Obstetrics and Gynaecology Canada
Andrea Y. Lausman and Enas Al-Yaseen and David Sam and Romy Nitsch and Jon F.R. Barrett and Wee-Shian Chan
DOI: 10.1016/s1701-2163(16)32995-4
11/2008

Recurrent venous thromboembolism after pregnancy-associated versus unprovoked thromboembolism
Thrombosis and Haemostasis
Richard H. White and Wee-Shian Chan and Hong Zhou and Jeffrey S. Ginsberg
DOI: 10.1160/th08-04-0238
07/2008

d-Dimer Testing in Pregnancy: Clinically Useful, but at What Cost?
Annals of Internal Medicine
Wee-Shian Chan
DOI: 10.7326/0003-4819-148-6-200803180-00021
03/2008

Author's response: Monitoring Anti-Xa to prevent thrombosis progression in pregnant women treated with low-molecular weight heparin
Thrombosis Research
Wee-Shian Chan
DOI: 10.1016/j.thromres.2007.11.001
01/2008

The “ART” of thromboembolism: A review of assisted reproductive technology and thromboembolic complications
Thrombosis Research
W.S. Chan and M.E. Dixon
DOI: 10.1016/j.thromres.2007.05.023
01/2008

A Red Blood Cell Agglutination d-Dimer Test to Exclude Deep Venous Thrombosis in Pregnancy
Annals of Internal Medicine
Wee-Shian Chan and Sanjeev Chunilal and Agnes Lee and Mark Crowther and Marc Rodger and Jeffrey S. Ginsberg
DOI: 10.7326/0003-4819-147-3-200708070-00005
08/2007

A review of upper extremity deep vein thrombosis in pregnancy: unmasking the 'ART' behind the clot
Journal of Thrombosis and Haemostasis
W.-S. CHAN and J. S. GINSBERG
DOI: 10.1111/j.1538-7836.2006.02026.x
08/2006

Risk of Stroke in Women Exposed to Low-Dose Oral Contraceptives
Archives of Internal Medicine
Wee-Shian Chan and Joel Ray and Eugene K. Wai and Shiphira Ginsburg and Mary E. Hannah and Paul N. Corey and Jeffrey S. Ginsberg
DOI: 10.1001/archinte.164.7.741
04/2004

Treatment of venous thromboembolism in pregnancy
Current Treatment Options in Cardiovascular Medicine
Wee Shian Chan
DOI: 10.1007/s11936-004-0043-2
04/2004

Maternal Body Mass Index and the Risk of Preeclampsia: A Systematic Overview
Epidemiology
Tara E. O’Brien and Joel G. Ray and Wee-Shian Chan
DOI: 10.1097/01.ede.0000059921.71494.d1
05/2003

Diagnosis of deep vein thrombosis and pulmonary embolism in pregnancy
Thrombosis Research
Wee-Shian Chan and Jeffrey S Ginsberg
DOI: 10.1016/s0049-3848(02)00105-6
08/2002

Suspected Pulmonary Embolism in Pregnancy
Archives of Internal Medicine
W. S. Chan and J. G. Ray and S. Murray and G. E. Coady and G. Coates and J. S. Ginsberg
DOI: 10.1001/archinte.162.10.1170
05/2002

Preconception Care and the Risk of Congenital Anomalies in the Offspring of Women With Diabetes Mellitus: A Meta-Analysis
Obstetrical and Gynecological Survey
J. G. Ray and T. E. O’Brien and W. S. Chan
DOI: 10.1097/00006254-200202000-00006
02/2002

Antithrombotic therapy during pregnancy
Seminars in Perinatology
Wee S. Chan and Sanjeev D. Chunilal and Jeffrey S. Ginsberg
DOI: 10.1053/sper.2001.24899
06/2001

Anticoagulation of Pregnant Women With Mechanical Heart Valves
Archives of Internal Medicine
Wee Shian Chan and Sonia Anand and Jeffrey S. Ginsberg
DOI: 10.1001/archinte.160.2.191
01/2000

Low Molecular Weight Heparin Use During Pregnancy: Issues of Safety and Practicality
Obstetrical & Gynecological Survey
Wee Shian Chan and Joel G. Ray
DOI: 10.1097/00006254-199910000-00022
10/1999

What Is the Optimal Management of Pregnant Women with Valvular Heart Disease in Pregnancy?
Pathophysiology of Haemostasis and Thrombosis
Wee Shian Chan
DOI: 10.1159/000054124
1999

Research
Grants

Canadian Institutes of Health Research Operating Grant Competition - Project: "A Pilot Study Assessing Feasibility of a Randomized, Placebo-controlled Trial of Low Molecular Weight-Heparin for Postpartum Prophylaxis in Women at Risk of Developing Venous Thromboembolism." Co-investigator. Total Funding: $450,000 (2010 - 2012)

Canadian Institutes of Health Research Control of Hypertension in Pregnancy Study. Co-investigator. (2009 - 2013)

National Institute of Health grant - Project: "Exploring Host Gene Expression during Post-Exertional Symptom Flare in ME/CFS: An experimental approach." Co-investigator. Total Funding: $271,828 (2015 - 2017)

Honours & Awards

2002/7 - 2003/1 Marion Hillard Award-School Fees, Women's College Hospital

2008/7 - 2009/6 Undergraduate Education Award, General Internal Medicine, Dept of Medicine, Faculty of Medicine Women's College Hospital. Description: In recognition of excellence in teaching, educational leadership and education administration at the undergraduate level.

2004/9 - Young Investigator's Award - Distinction, Sunnybrook and Women's Health Sciences Centre