Bruce Bjornson

FRCPC, MD, BSc (Med)

Investigator, BC Children's Hospital Research Insitute
Medical Director, Brain Mapping, Neuroinformatics & Neurotechnology Laboratory
Facility Director, BCCH MRI Research Facility

My research focuses on the application of multi-modality functional neuroimaging methods, which link abnormalities of neurological function to demonstrable alterations of neuroanatomy and neurophysiology, and thereby enhance understanding of neurological disorders in infants, children and young adults with stroke, brain injuries (e.g., sports concussions), epilepsy and other neurological disorders, which have impact upon developing brain networks (connectomics), especially those involving language, perception and motor function. I collaborate with regional, national and international colleagues to evaluate and enhance neurological care outcomes, using pediatric MRI simulation, neuroinformatics and neurotechnology development to deliver advanced pediatric functional MRI brain mapping methodologies, optimized for children through ongoing quality improvement and translational personalized pediatric neurological care research.

Academic Affiliations

  • Clinical Assistant Professor, Division of Neurology, Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Evidence to Innovation
  • Research Group(s): Clinical and Community Data, Analytics and Informatics; Neurodevelopmental and Neurological Disorders

Challenges and opportunities for advancing functional MRI in clinical practice.

Brain : a journal of neurology

Voets NL and Price CJ and Glasser MF and Benjamin C and Rutten GJ and Plaha P and Benzinger T and Mian A and Gawryluk J and Pernet C and Jones OP and Haller S and Sierpowska J and Talib G and Bartsch AJ

DOI: 10.1093/brain/awaf053 PubMed: 39965101

02 / 2025

Consensus recommendations for clinical functional MRI applied to language mapping

Aperture Neuro

Natalie L. Voets and Manzar Ashtari and Christian F. Beckmann and Christopher F. Benjamin and Tammie Benzinger and Jeffrey R. Binder and Alberto Bizzi and Bruce Bjornson and Edward F. Chang and Linda Douw and Jodie Gawryluk and Karsten Geletneky and Matthew F. Glasser and Sven Haller and Mark Jenkinson and Jorge Jovicich and Eric Leuthardt and Asim Mian and Thomas E. Nichols and Oiwi Parker Jones and Cyril Pernet and Puneet Plaha and Monika Polczynska-Bletsos and Cathy J. Price and Geert-Jan Rutten and Michael Scheel and Joshua S. Shimony and Joanna Sierpowska and Lynne J. Williams and Ghoufran Talib and Michael Zeineh and Andreas Bartsch and Susan Bookheimer

DOI: 10.52294/001c.128149

01 / 2025

Longitudinal changes in brain metabolites following pediatric concussion

Scientific Reports

La, P.L. and Walker, R. and Bell, T.K. and Craig, W. and Doan, Q. and Beauchamp, M.H. and Zemek, R. and Harris, A.D. and Yeates, K.O. and Bjornson, B.H. and Gravel, J. and Mikrogianakis, A. and Goodyear, B. and Abdeen, N. and Beaulieu, C. and Dehaes, M. and Deschenes, S. and Lebel, C. and Lamont, R. and Williamson, T. and Barlow, K.M. and Bernier, F. and Brooks, B.L. and Emery, C. and Freedman, S.B. and Kowalski, K. and Mrklas, K. and Tomfohr-Madsen, L. and Schneider, K.J.

DOI: 10.1038/s41598-024-52744-7

Pharmacological and physiological effects of cannabidiol: a dose escalation, placebo washout study protocol

BMC Neurology

Neary, J.P. and Singh, J. and Alcorn, J. and Laprairie, R.B. and Dehghani, P. and Mang, C.S. and Bjornson, B.H. and Hadjistavropoulos, T. and Bardutz, H.A. and Bhagaloo, L. and Walsh, Z. and Szafron, M. and Dorsch, K.D. and Thompson, E.S.

DOI: 10.1186/s12883-024-03847-1

Do preinjury life events moderate the outcomes of mild traumatic brain injuries in children? An A-CAP Study

Journal of Pediatric Psychology

Dharsee, S. and Tang, K. and Beauchamp, M.H. and Craig, W. and Doan, Q. and Freedman, S.B. and Gravel, J. and Zemek, R. and Yeates, K.O. and Bjornson, B.H. and Mikrogianakis, A. and Goodyear, B. and Abdeen, N. and Beaulieu, C. and Dehaes, M. and Deschenes, S. and Harris, A. and Lebel, C. and Lamont, R. and Williamson, T. and Barlow, K.M. and Bernier, F. and Brooks, B.L. and Emery, C. and Kowalski, K. and Mrklas, K. and Tomfohr-Madsen, L. and Schneider, K.J.

DOI: 10.1093/jpepsy/jsae007

Longitudinal Functional Connectome in Pediatric Concussion: An Advancing Concussion Assessment in Pediatrics Study.

Journal of neurotrauma

Adrian Onicas and Deighton S and Yeates KO and Bray S and Graff K and Abdeen N and Beauchamp MH and Beaulieu C and Bruce H. Bjornson and Craig W and Dehaes M and Deschenes S and Doan Q and Freedman SB and Goodyear BG and Gravel J and Lebel C and Ledoux AA and Zemek R and Ware AL

DOI: 10.1089/neu.2023.0183 PubMed: 37489293

08 / 2023

The development of the pediatric stroke neuroimaging platform (PEDSNIP).

NeuroImage. Clinical

Domi T and Robertson A and Lee W and Wintle RF and Stence N and Bernard T and Kirton A and Carlson H and Andrade A and Rafay MF and Bruce H. Bjornson and Kim D and Dowling M and Bonnett W and Rivkin M and Krishnan P and Shroff M and Ertl-Wagner B and Strother S and Arnott S and Wintermark M and Kassner A and deVeber G and Dlamini N

DOI: 10.1016/j.nicl.2023.103438 PubMed: 37354865

05 / 2023

Association of Posttraumatic Headache With Symptom Burden After Concussion in Children.

JAMA network open

van Ierssel JJ and Tang K and Beauchamp M and Bresee N and Cortel-LeBlanc A and Craig W and Doan Q and Gravel J and Lyons T and Mannix R and Orr S and Zemek R and Yeates KO and Pediatric Emergency Research Canada A-CAP study team

DOI: 10.1001/jamanetworkopen.2023.1993 PubMed: 36884251

03 / 2023

Altered longitudinal structural connectome in paediatric mild traumatic brain injury: an Advancing Concussion Assessment in Paediatrics study

Brain Communications

Ware, A.L. and Onicas, A.I. and Abdeen, N. and Beauchamp, M.H. and Beaulieu, C. and Bjornson, B.H. and Craig, W. and Dehaes, M. and Deschenes, S. and Doan, Q. and Freedman, S.B. and Goodyear, B.G. and Gravel, J. and Ledoux, A.-A. and Zemek, R. and Yeates, K.O. and Lebel, C.

DOI: 10.1093/braincomms/fcad173

Longitudinal Gray Matter Trajectories in Pediatric Mild Traumatic Brain Injury

Neurology

Ware, A.L. and Lebel, C. and Onicas, A. and Abdeen, N. and Beauchamp, M.H. and Beaulieu, C. and Bjornson, B.H. and Craig, W. and Dehaes, M. and Doan, Q. and Deschenes, S. and Freedman, S.B. and Goodyear, B.G. and Gravel, J. and Ledoux, A.-A. and Zemek, R. and Yeates, K.O.

DOI: 10.1212/WNL.0000000000207508

IQ After Pediatric Concussion

Pediatrics

Ware, A.L. and McLarnon, M.J.W. and Lapointe, A.P. and Brooks, B.L. and Bacevice, A. and Bangert, B.A. and Beauchamp, M.H. and Bigler, E.D. and Bjornson, B. and Cohen, D.M. and Craig, W. and Doan, Q. and Freedman, S.B. and Goodyear, B.G. and Gravel, J. and Leslie K. Mihalov, H. and Minich, N.M. and Gerry Taylor, H. and Zemek, R. and Yeates, K.O.

DOI: 10.1542/peds.2022-060515

International Prevalence and Mechanisms of SARS-CoV-2 in Childhood Arterial Ischemic Stroke During the COVID-19 Pandemic.

Stroke

Beslow LA and Agner SC and Santoro JD and Ram D and Wilson JL and Harrar D and Appavu B and Fraser SM and Rossor T and Torres MD and Kossorotoff M and Zuiga Zambrano YC and International Pediatric Stroke Study Group

DOI: 10.1161/strokeaha.121.038250 PubMed: 35380052

04 / 2022

Comparison of CPU and GPU bayesian estimates of fibre orientations from diffusion MRI.

PloS one

Kim DHC and Williams LJ and Hernandez-Fernandez M and Bruce H. Bjornson

DOI: 10.1371/journal.pone.0252736 PubMed: 35446840

04 / 2022

Longitudinal white matter microstructural changes in pediatric mild traumatic brain injury: An A-CAP study

Human Brain Mapping

Ware, A.L. and Yeates, K.O. and Tang, K. and Shukla, A. and Onicas, A.I. and Guo, S. and Goodrich-Hunsaker, N. and Abdeen, N. and Beauchamp, M.H. and Beaulieu, C. and Bjornson, B. and Craig, W. and Dehaes, M. and Doan, Q. and Deschenes, S. and Freedman, S.B. and Goodyear, B.G. and Gravel, J. and Ledoux, A.-A. and Zemek, R. and Lebel, C.

DOI: 10.1002/hbm.25885

Prenatal antidepressant exposure and sex differences in neonatal corpus callosum microstructure.

Developmental psychobiology

Campbell KSJ and Williams LJ and Bjornson BH and Weik E and Brain U and Grunau RE and Miller SP and Oberlander TF

DOI: 10.1002/dev.22125 PubMed: 33942888

05 / 2021

Functional Magnetic Resonance Imaging Findings in Children and Adolescents With Chronic Kidney Disease: Preliminary Findings

Seminars in Nephrology

Harrell, W. and Gipson, D.S. and Belger, A. and Matsuda-Abedini, M. and Bjornson, B. and Hooper, S.R.

DOI: 10.1016/j.semnephrol.2021.09.009

Imaging Predictors of Neurologic Outcome After Pediatric Arterial Ischemic Stroke.

Stroke

Jiang B and Hills NK and Forsyth R and Jordan LC and Slim M and Pavlakis SG and Freidman N and Dlamini N and Farooq O and Li Y and Zhu G and Fullerton H and Wintermark M and Lo WD and VIPS Investigators*

DOI: 10.1161/strokeaha.120.030965 PubMed: 33280552

12 / 2020

Comparative study of posterior and anterior circulation stroke in childhood: Results from the International Pediatric Stroke Study.

Neurology

Goeggel Simonetti B and Rafay MF and Chung M and Lo WD and Beslow LA and Billinghurst LL and Fox CK and Pagnamenta A and Steinlin M and Mackay MT and IPSS Study Group

DOI: 10.1212/wnl.0000000000008837 PubMed: 31857436

12 / 2019

Comparison of CPU and GPU Bayesian Estimates of Fibre Orientations from Diffusion MRI

Kim DH and Williams LJ and Hernandez-Fernandez M and Bjornson BH

DOI: 10.1101/703835

07 / 2019

Diagnostic Yield and Treatment Impact of Targeted Exome Sequencing in Early-Onset Epilepsy.

Frontiers in neurology

Demos M and Guella I and DeGuzman C and McKenzie MB and Buerki SE and Evans DM and Toyota EB and Boelman C and Huh LL and Datta A and Michoulas A and Selby K and Bjornson BH and Horvath G and Farrer MJ

DOI: 10.3389/fneur.2019.00434 PubMed: 31164858

05 / 2019

Hub distribution of the brain functional networks of newborns prenatally exposed to maternal depression and SSRI antidepressants.

Depression and anxiety

Rotem-Kohavi N and Williams LJ and Muller AM and Abdi H and Virji-Babul N and Bjornson BH and Brain U and Werker JF and Grunau RE and Miller SP and Oberlander TF

DOI: 10.1002/da.22906 PubMed: 31066992

05 / 2019

Alterations in Resting-State Networks Following In Utero Selective Serotonin Reuptake Inhibitor Exposure in the Neonatal Brain

Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Rotem-Kohavi, N. and Williams, L.J. and Virji-Babul, N. and Bjornson, B.H. and Brain, U. and Werker, J.F. and Grunau, R.E. and Miller, S.P. and Oberlander, T.F.

DOI: 10.1016/j.bpsc.2018.08.004

Socioeconomic determinants of outcome after childhood arterial ischemic stroke.

Neurology

Jordan LC and Hills NK and Fox CK and Ichord RN and Pergami P and deVeber GA and Fullerton HJ and Lo W and VIPS Investigators

DOI: 10.1212/wnl.0000000000005946 PubMed: 29980641

07 / 2018

Dyslipidemia in Children With Arterial Ischemic Stroke: Prevalence and Risk Factors

Pediatric Neurology

Sultan, S. and Dowling, M. and Kirton, A. and DeVeber, G. and Linds, A. and Elkind, M.S.V. and Bernard, T. and Dowling, M. and Hernandez, M. and Rivkin, M. and Kopyta, I. and Ichord, R. and Benedict, S. and Mackay, M. and Kirton, A. and Zafeiriou, D. and Troncoso, M. and Yager, J. and Abraham, L. and Lo, W. and Gonzalez, V. and Saengpattrachai, M. and Chan, A. and Abdallah, A. and Brankovic-Sreckovic, V. and Kolk, A. and Carpenter, J. and Kovacevic, G. and Amlie-Lefond, C. and Steinlin, M. and Paolicchi, J. and Carell, M. and Bjornson, B. and Kosofsky, B. and Wong, V. and Pergami, P. and Friedman, N. and Guang, Y. and Humphreys, P. and Nowak-Gttl, U. and Ferriero, D. and Xavier, F. and Fryer, R. and Andrade Alveal, L. and Altuna, D. and Felling, R. and Pavlakis, S. and Grabowski, E. and Golomb, M. and Noetzel, M. and Khoury, C. and Lerner, N. and Blair, A. and Rafay, M.

DOI: 10.1016/j.pediatrneurol.2017.09.019

Brain abnormalities in children and adolescents with chronic kidney disease

Pediatric Research

Matsuda-Abedini, M. and Fitzpatrick, K. and Harrell, W.R. and Gipson, D.S. and Hooper, S.R. and Belger, A. and Poskitt, K. and Miller, S.P. and Bjornson, B.H.

DOI: 10.1038/s41390-018-0037-5

Clinical and Imaging Characteristics of Arteriopathy Subtypes in Children with Arterial Ischemic Stroke: Results of the VIPS Study.

AJNR. American journal of neuroradiology

Wintermark M and Hills NK and DeVeber GA and Barkovich AJ and Bernard TJ and Friedman NR and Mackay MT and Kirton A and Zhu G and Leiva-Salinas C and Hou Q and Fullerton HJ and VIPS Investigators

DOI: 10.3174/ajnr.A5376 PubMed: 28982784

10 / 2017

Advancing Concussion Assessment in Pediatrics (A-CAP): A prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: Protocol study

BMJ Open

Yeates, K.O. and Beauchamp, M. and Craig, W. and Doan, Q. and Zemek, R. and Bjornson, B. and Gravel, J. and Mikrogianakis, A. and Goodyear, B. and Abdeen, N. and Beaulieu, C. and Dehaes, M. and Deschenes, S. and Harris, A. and Lebel, C. and Lamont, R. and Williamson, T. and Barlow, K.M. and Bernier, F. and Brooks, B.L. and Emery, C. and Freedman, S.B. and Kowalski, K. and Mrklas, K. and Tomfohr-Madsen, L. and Schneider, K.J.

DOI: 10.1136/bmjopen-2017-017012

Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke Registry

Pediatric Neurology

deVeber, G.A. and Kirton, A. and Booth, F.A. and Yager, J.Y. and Wirrell, E.C. and Wood, E. and Shevell, M. and Surmava, A.-M. and McCusker, P. and Massicotte, M.P. and MacGregor, D. and MacDonald, E.A. and Meaney, B. and Levin, S. and Lemieux, B.G. and Jardine, L. and Humphreys, P. and David, M. and Chan, A.K.C. and Buckley, D.J. and Bjornson, B.H.

DOI: 10.1016/j.pediatrneurol.2017.01.016

Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for ChildrenWorkshop

Pediatric Neurology

Dlamini, N. and Wintermark, M. and Fullerton, H. and Strother, S. and Lee, W. and Bjornson, B. and Guilliams, K.P. and Miller, S. and Kirton, A. and Filippi, C.G. and Linds, A. and Askalan, R. and deVeber, G.

DOI: 10.1016/j.pediatrneurol.2017.01.006

Further Validation of the SIGMAR1 c.151+1G>T Mutation as Cause of Distal Hereditary Motor Neuropathy.

Child neurology open

DOI: 10.1177/2329048x16669912 PubMed: 28503617

Surface displacement based shape analysis of central brain structures in preterm-born children

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Garg, A. and Grunau, R.E. and Popuri, K. and Miller, S. and Bjornson, B. and Poskitt, K.J. and Beg, M.F.

DOI: 10.1117/12.2216914

Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence

Stroke

Fullerton, H.J. and Deveber, G.A. and Hills, N.K. and Dowling, M.M. and Fox, C.K. and Mackay, M.T. and Kirton, A. and Yager, J.Y. and Bernard, T.J. and Hod, E.A. and Wintermark, M. and Elkind, M.S.V. and Benedict, S.L. and Bernard, T.J. and Fox, C.K. and deVeber, G.A. and Friedman, N.R. and Lo, W.D. and Ichord, R.N. and Tan, M.A. and Mackay, M.T. and Kirton, A. and Hernandez-Chavez, M.I. and Humphreys, P. and Jordan, L.C. and Sultan, S. and Rivkin, M.J. and Rafay, M.F. and Titomanlio, L. and Kovacevic, G.S. and Yager, J.Y. and Amlie-Lefond, C. and Dlamini, N. and Condie, J. and Yeh, A. and Kneen, R. and Bjornson, B. and Pergami, P. and Zou, L.P. and Elbers, J.M. and Abdalla, A. and Chan, A.K. and Farooq, O. and Lim, M.J. and Carpenter, J.L. and Pavlakis, S. and Wong, V.C. and Forsyth, R.

DOI: 10.1161/STROKEAHA.116.013719

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis?

Stroke

Wei, F. and Diedrich, K.T. and Fullerton, H.J. and DeVeber, G. and Wintermark, M. and Hodge, J. and Kirton, A. and Dowling, M.M. and Benedict, S.L. and Bernard, T.J. and Fox, C.K. and Friedman, N.R. and Lo, W.D. and Ichord, R.N. and Tan, M.A. and Mackay, M.T. and Hernandez Chavez, M.I. and Humphreys, P. and Jordan, L.C. and Sultan, S.M. and Rivkin, M.J. and Rafay, M.F. and Titomanlio, L. and Kovacevic, G.S. and Yager, J.Y. and Amlie-Lefond, C. and Dlamini, N. and Condie, J. and Yeh, E.A. and Kneen, R. and Bjornson, B.H. and Pergami, P. and Zou, L.P. and Elbers, J. and Abdalla, A. and Chan, A.K. and Farooq, O. and Lim, M.J. and Carpenter, J.L. and Pavlakis, S. and Wong, V.C.N. and Forsyth, R.

DOI: 10.1161/STROKEAHA.115.011331

Risk of Recurrent Arterial Ischemic Stroke in Childhood: A Prospective International Study.

Fullerton HJ and Wintermark M and Hills NK and Dowling MM and Tan M and Rafay MF and Elkind MS and Barkovich AJ and deVeber GA and VIPS Investigators

DOI: 10.1161/STROKEAHA.115.011173 PubMed: 26556824

Neonatal Pain and Infection Relate to Smaller Cerebellum in Very Preterm Children at School Age

Journal of Pediatrics

Ranger, M. and Zwicker, J.G. and Chau, C.M.Y. and Park, M.T.M. and Chakravarthy, M.M. and Poskitt, K. and Miller, S.P. and Bjornson, B.H. and Tam, E.W.Y. and Chau, V. and Synnes, A.R. and Grunau, R.E.

DOI: 10.1016/j.jpeds.2015.04.055

Infection, vaccination, and childhood arterial ischemic stroke: Results of the VIPS study.

Fullerton HJ and Hills NK and Elkind MS and Dowling MM and Wintermark M and Glaser CA and Tan M and Rivkin MJ and Titomanlio L and Barkovich AJ and deVeber GA and VIPS Investigators

DOI: 10.1212/WNL.0000000000002065 PubMed: 26423434

Antithrombotic therapy for secondary stroke prevention in bacterial meningitis in children

J Pediatr

Boelman, C. and Shroff, M. and Yau, I. and Bjornson, B. and Richrdson, S. and deVeber, G. and MacGregor, D. and Moharir, M. and Askalan, R.

DOI: 10.1016/j.jpeds.2014.06.013

Manually segmented template library for 8-year-old pediatric brain MRI data with 16 subcortical structures

Journal of Medical Imaging

Garg, A. and Wong, D. and Popuri, K. and Poskitt, K.J. and Fitzpatrick, K. and Bjornson, B. and Grunau, R.E. and Beg, M.F.

DOI: 10.1117/1.JMI.1.3.034502

Invasive procedures in preterm children: Brain and cognitive development at school age

Pediatrics

Vinall, J. and Miller, S.P. and Bjornson, B.H. and Fitzpatrick, K.P.V. and Poskitt, K.J. and Brant, R. and Synnes, A.R. and Cepeda, I.L. and Grunau, R.E.

DOI: 10.1542/peds.2013-1863

Classification of FMRI patterns-A study of the language network segregation in pediatric localization related epilepsy

Human Brain Mapping

Wang, J. and You, X. and Wu, W. and Guillen, M.R. and Cabrerizo, M. and Sullivan, J. and Donner, E. and Bjornson, B. and Gaillard, W.D. and Adjouadi, M.

DOI: 10.1002/hbm.22265

Cerebellar language mapping and cerebral language dominance in pediatric epilepsy surgery patients

NeuroImage: Clinical

Gelinas, J.N. and Fitzpatrick, K.P.V. and Kim, H.C. and Bjornson, B.H.

DOI: 10.1016/j.nicl.2014.06.016

The effects of pediatric epilepsy on a language connectome

Human Brain Mapping

Eddin, A.S. and Wang, J. and Wu, W. and Sargolzaei, S. and Bjornson, B. and Jones, R.A. and Gaillard, W.D. and Adjouadi, M.

DOI: 10.1002/hbm.22600

Arteriopathy diagnosis in childhood arterial ischemic stroke: Results of the vascular effects of infection in pediatric stroke study

Stroke

Wintermark, M. and Hills, N.K. and DeVeber, G.A. and Barkovich, A.J. and Elkind, M.S.V. and Sear, K. and Zhu, G. and Leiva-Salinas, C. and Hou, Q. and Dowling, M.M. and Bernard, T.J. and Friedman, N.R. and Ichord, R.N. and Fullerton, H.J. and Benedict, S.L. and Fox, C.K. and Lo, W.D. and Tan, M.A. and Mackay, M.T. and Kirton, A. and Hernandez Chavez, M.I. and Humphreys, P. and Jordan, L.C. and Sultan, S.M. and Rivkin, M.J. and Rafay, M.F. and Titomanlio, L. and Kovacevic, G.S. and Yager, J.Y. and Amlie-Lefond, C. and Dlamini, N. and Condie, J. and Yeh, A. and Kneen, R. and Bjornson, B.H. and Pergami, P. and Zou, L.P. and Elbers, J. and Abdalla, A. and Chan, A.K. and Farooq, O. and Lim, M.J. and Carpenter, J.L. and Pavlakis, S. and Wong, V.C. and Forsyth, R.

DOI: 10.1161/STROKEAHA.114.007404

A decisional space for fMRI pattern separation using the principal component analysis-a comparative study of language networks in pediatric epilepsy

Human Brain Mapping

You, X. and Adjouadi, M. and Wang, J. and Guillen, M.R. and Bernal, B. and Sullivan, J. and Donner, E. and Bjornson, B. and Berl, M. and Gaillard, W.D.

DOI: 10.1002/hbm.22069

Neonatal Pain-Related Stress Predicts Cortical Thickness at Age 7 Years in Children Born Very Preterm

PLoS ONE

Ranger, M. and Chau, C.M.Y. and Garg, A. and Woodward, T.S. and Beg, M.F. and Bjornson, B. and Poskitt, K. and Fitzpatrick, K. and Synnes, A.R. and Miller, S.P. and Grunau, R.E.

DOI: 10.1371/journal.pone.0076702

Serial monitoring of CO2 reactivity following sport concussion using hypocapnia and hypercapnia

Brain Injury

Len, T.K. and Neary, J.P. and Asmundson, G.J.G. and Candow, D.G. and Goodman, D.G. and Bjornson, B. and Bhambhani, Y.N.

DOI: 10.3109/02699052.2012.743185

Cortical basis for dichotic pitch perception in developmental dyslexia

Brain and Language

Partanen, M. and Fitzpatrick, K. and Mdler, B. and Edgell, D. and Bjornson, B. and Giaschi, D.E.

DOI: 10.1016/j.bandl.2012.09.002

Sub-patterns of language network reorganization in pediatric localization related epilepsy: A multisite study

Human Brain Mapping

You, X. and Adjouadi, M. and Guillen, M.R. and Ayala, M. and Barreto, A. and Rishe, N. and Sullivan, J. and Dlugos, D. and Vanmeter, J. and Morris, D. and Donner, E. and Bjornson, B. and Smith, M.L. and Bernal, B. and Berl, M. and Gaillard, W.D.

DOI: 10.1002/hbm.21066

Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study.

Kirton A and Armstrong-Wells J and Chang T and Deveber G and Rivkin MJ and Hernandez M and Carpenter J and Yager JY and Lynch JK and Ferriero DM and International Pediatric Stroke Study Investigators

DOI: 10.1542/peds.2011-1148

Cerebrovascular reactivity impairment after sport-induced concussion

Medicine and Science in Sports and Exercise

Len, T.K. and Neary, J.P. and Asmundson, G.J.G. and Goodman, D.G. and Bjornson, B. and Bhambhani, Y.N.

DOI: 10.1249/MSS.0b013e3182249539

The role of area V5/{MT}$\mathplus$ in the centripetal bias in global motion perception

Journal of Vision

D. Giaschi and A. Zwicker and S. A. Young and B. Lee and B. Bjornson

DOI: 10.1167/7.9.751

Antithrombotic treatment in neonatal cerebral sinovenous thrombosis: results of the International Pediatric Stroke Study.

Jordan LC and Rafay MF and Smith SE and Askalan R and Zamel KM and deVeber G and Ashwal S and International Pediatric Stroke Study Group

DOI: 10.1016/j.jpeds.2009.11.061

Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study.

Amlie-Lefond C and deVeber G and Chan AK and Benedict S and Bernard T and Carpenter J and Dowling MM and Fullerton H and Hovinga C and Kirton A and Lo W and Zamel K and Ichord R and International Pediatric Stroke Study

DOI: 10.1016/s1474-4422(09)70106-1 PubMed: 19423401

06 / 2009

Male predominance in childhood ischemic stroke: findings from the international pediatric stroke study.

Golomb MR and Fullerton HJ and Nowak-Gottl U and Deveber G and International Pediatric Stroke Study Group

DOI: 10.1161/strokeaha.108.521203 PubMed: 18787197

01 / 2009

Combined functional MRI and diffusion tensor imaging analysis of visual motion pathways

Journal of Neuro-Ophthalmology

Lanyon, L.J. and Giaschi, D. and Young, S.A. and Fitzpatrick, K. and Diao, L. and Bjornson, B.H. and Barton, J.J.S.

DOI: 10.1097/WNO.0b013e3181a58ef8

Overlapping cortical systems for reading and temporal processing

CANADIAN JOURNAL OF EXPERIMENTAL PSYCHOLOGY-REVUE CANADIENNE DE PSYCHOLOGIE EXPERIMENTALE

PARTANEN, M and EDGELL, D and BJORNSON, B and GIASCHI, D

Intracranial calcification after cord blood neonatal transplantation for Krabbe disease

Neuropediatrics

Lehman, A.M. and Schultz, K.R. and Poskitt, K. and Bjornson, B. and Keyes, R. and Waters, P.J. and Clarke, L.A. and Everett, R. and McConnell, D. and Stockler, S.

DOI: 10.1055/s-0029-1243189

Cerebral venous sinus thrombosis and common childhood illness

JOURNAL OF THE NEUROLOGICAL SCIENCES

BILLINGHURST, L and BJORNSON, B and BOOTH, F and CAMFIELD, C and DAVID, M and GILLETT, J and HUMPHREYS, P and JARDINE, L and LANGEVIN, P and MACDONALD, EA and MEANEY, B and PRIEUR, B and SHEVELL, M and SINCLAIR, DB and WOOD, E and YAGER, J and ADAMS, C and ANDREW, M and DEVEBER, G

DOI: 10.1016/s0022-510x(09)70417-4

Integrating nonlinear decision functions with principal component analysis in fMRI language activation patterns classification

Epilepsia

ADJOUADI, M and YOU, XZ and GUILLEN, M and AYALA, M and CABRERIZO, M and JAYAKAR, P and BARRETO, A and RISHE, N and SULLIVAN, J and DLUGOS, D and BERL, M and VANMETER, J and MORRIS, D and DONNER, E and BJORNSON, B and SMITH, M and BERNAL, B and GAILLARD, WD

Pediatric functional imaging consortium: sub-patterns of language dominance in pediatric localization related epilepsy identified by data driven separation analysis

EPILEPSIA

GAILLARD, WD and YOU, X and BERNAL, B and GUILLEN, MR and AYALA, M and JAYAKAR, P and BARRETO, A and RISHE, N and SULLIVAN, J and DLUGOS, D and BERL, MM and VANMETER, J and MORRIS, D and DONNER, E and BJORNSON, B and SMITH, M and ADJOUADI, M

Presurgical Visualization of Cerebral Surface Veins with Susceptibility Weighted Imaging

17th Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)

Al-Rekabi Z

Memory-based anti-saccade tasks increase response time and decrease pro-anti

Journal of Sport & Exercise Psychology

BAYLESS, SJ and GOODMAN, D and BJORNSON, B and GAETZ, M

Anti-basal ganglia antibodies and acute movement disorder following herpes zoster and streptococcal infections

European Journal of Paediatric Neurology

Basheer, S.N. and Wadsworth, L.D. and Bjornson, B.H.

DOI: 10.1016/j.ejpn.2006.11.001

The role of cortical area V5/MT+ in speed-tuned directional anisotropies in global motion perception

Vision Research

Giaschi, D. and Zwicker, A. and Young, S.A. and Bjornson, B.

DOI: 10.1016/j.visres.2006.12.017

Genotypic heterogeneity and clinical phenotype in triple A syndrome: A review of the NIH experience 2000-2005

Clinical Genetics

Brooks, B.P. and Kleta, R. and Stuart, C. and Tuchman, M. and Jeong, A. and Stergiopoulos, S.G. and Bei, T. and Bjornson, B. and Russell, L. and Chanonine, J.-P. and Tsagarakis, S. and Kalsner, L.R. and Stratakis, C.A.

DOI: 10.1111/j.1399-0004.2005.00482.x

Asymmetrical cortical activation by global motion in children with dyslexia

Journal of Vision

Giaschi, Deborah and Edwards, Veronica and Young, Simon Au and Bjornson, Bruce

DOI: 10.1167/5.8.848

Psychophysical indexes of temporal processing abnormalities in children with developmental dyslexia

Developmental Neuropsychology

Edwards, V.T. and Giaschi, D.E. and Dougherty, R.F. and Edgell, D. and Bjornson, B.H. and Lyons, C. and Douglas, R.M.

DOI: 10.1207/s15326942dn2503_5

Conscious visual abilities in a patient with early bilateral occipital damage.

Giaschi D and Jan JE and Bjornson B and Young SA and Tata M and Lyons CJ and Good WV and Wong PK

DOI: 10.1017/s0012162203001439 PubMed: 14580134

11 / 2003

Overcoming activation-induced registration errors in fMRI

Proceedings of SPIE - The International Society for Optical Engineering

Orchard, J.J. and Greif, C. and Golub, G.H. and Bjornson, B. and Atkins, M.S.

DOI: 10.1117/12.480849

Simultaneous registration and activation detection for fMRI

IEEE Transactions on Medical Imaging

Orchard, J. and Greif, C. and Golub, G.H. and Bjornson, B. and Atkins, M.S.

DOI: 10.1109/TMI.2003.819294

Conscious visual abilities in a patient with early bilateral occipital damage

Journal of Vision

Giaschi, D. and Bjornson, B. and Jan, J. and Tata, M. and Young, S.A. and Lyons, C.J. and Good, W.V. and Wong, P.K.H.

DOI: 10.1167/2.7.428

Hemispheric dissociation of verb generation from verb reading: functional MRI of an adolescent with early left MCA infraction

NEUROIMAGE

BJORNSON, B and GIASCHI, D and SLICK, D and CONNOLLY, M and YOUNG, SA

Hemispheric dissociation of verb generation from verb reading: functional MRI of an adolescent with early left MCA infarction

NEUROIMAGE

BJORNSON, B and GIASCHI, D and SLICK, D and CONNOLLY, M and YOUNG, SA

DOI: 10.1016/S1053-8119(01)91851-8

Cerebral sinovenous thrombosis in children

New England Journal of Medicine

DeVeber, G. and Andrew, M. and Adams, C. and Bjornson, B. and Booth, F. and Buckley, D.J. and Camfield, C.S. and David, M. and Humphreys, P. and Langevin, P. and MacDonald, E.A. and Gillett, J.

DOI: 10.1056/NEJM200108093450604

fMRI activation and residual vision for rapid movement in a case of bilateral cortical blindness due to early occipital damage

NEUROIMAGE

GIASCHI, D and BJORNSON, B and JAN, J and YOUNG, SA and TATA, M and WONG, P

DOI: 10.1016/s1053-8119(01)92228-1

Cortical mechanisms of central pitch processing revealed by dichotic pitch stimuli

{NeuroImage}

Deborah Giaschi and Bruce Bjornson and Robert Dougherty and Simon Au Young

DOI: 10.1016/s1053-8119(00)91633-1

High resolution EEG & seizure localization

NeuroImage

Wong, P.K.H. and Bjornson, B. and Connolly, M. and Steinbok, P. and Young, S.A. and Giaschi, D. and Gregory, D. and Smith, S. and Lee, R. and Man, A. and Cochrane, D.

Non-invasive mapping of sensorimotor cortex in a child with a cavernous angioma: FMRI and high-resolution EEG compared with surgical mapping

NeuroImage

Bjornson, B. and Giaschi, D. and Cochrane, D. and Au Young, S. and Rootman, D. and Boden, C. and Connolly, M. and Poskitt, K. and Boyle, C. and Smith, S. and Akagemi, R. and Wong, P.K.H.

High resolution EEG & seizure localization

NeuroImage

Wong, P.K.H. and Bjornson, B. and Connolly, M. and Steinbok, P. and Young, S.A. and Giaschi, D. and Gregory, D. and Smith, S. and Lee, R. and Man, A. and Cochrane, D.

Dichotic pitch

NeuroReport

Robert F. Dougherty and Max S. Cynader and Bruce H. Bjornson and Dorothy Edgell and Deborah E. Giaschi

DOI: 10.1097/00001756-199809140-00015 PubMed: 9804305

09 / 1998

Comparison of visual activation measured by fMRI and high resolution EEG

NeuroImage

Dougherty, R.F. and Au Young, S.M.W. and Giaschi, D.E. and Bjornson, B.H. and Wong, P.K.H.

Dichotic pitch: A new stimulus distinguishes normal and dyslexic auditory function

NeuroReport

Dougherty, R.F. and Cynader, M.S. and Bjornson, B.H. and Edgell, D. and Giaschi, D.E.

Basal ganglia infarction associated with HHV-6 infection

Archives of Disease in Childhood

Webb, D.W. and Bjornson, B.H. and Sargent, M.A. and Hukin, J. and Thomas, E.E.

PubMed: 9166034

In search of the best psychophysical indicator of an M-stream deficit in developmental dyslexia

Investigative Ophthalmology and Visual Science

Dougherty, R.F. and Giaschi, D.E. and Bjornson, B.H. and Chamul, S.L. and Edgcll, D. and Lyons, C.J.

Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy.

Packard AB and Roach PJ and Davis RT and Carmant L and Davis R and Riviello J and Holmes G and Barnes PD and O'Tuama LA and Bjornson B and Treves ST

PubMed: 8965177

07 / 1996

Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy

Journal of Nuclear Medicine

Packard, A.B. and Roach, P.J. and Davis, R.T. and Carmant, L. and Davis, R. and Riviello, J. and Holmes, G. and Barnes, P.D. and O'Tuama, L.A. and Bjornson, B. and Treves, S.T.

PubMed: 8965177

Cerebral infarction in childhood: is the left hemisphere more susceptible to ischemic injury?

30th Meeting of the Canadian Congress of Neurological Sciences

DOI: 10.1017/s0317167100039391

06 / 1995

Brain

Pediatric Nuclear Medicine, Second Edition

L. A. O'Tuama and B. Bjornson and H. Chugani and S. T. Treves

DOI: 10.1007/978-1-4757-4205-3_6

Computed Tomography Imaging in Children with Head Trauma: Utilization and Appropriateness from a Quality Improvement Perspective

Infection Control and Hospital Epidemiology

Montserrat Vera and Gary R. Fleisher and Patrick D. Barnes and Bruce H. Bjornson and Elizabeth N. Allred and Donald A. Goldmann

DOI: 10.2307/30145525 PubMed: 8376744

08 / 1993

Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias.

O'Tuama LA and Urion DK and Janicek MJ and Treves ST and Bjornson B and Moriarty JM

PubMed: 1383478

10 / 1992

Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias

Journal of Nuclear Medicine

O'Tuama, L.A. and Urion, D.K. and Janicek, M.J. and Treves, S.T. and Bjornson, B. and Moriarty, J.M.

PubMed: 1383478

Cerebral perfusion abnormalities in Kleffner-Landau syndrome.

American Academy of Neurology 43rd Annual Meeting, Boston, MA, April 21-27, 1991

Treves ST

03 / 1991

Clinical functional MRI for language mapping: Best Practice recommendations from the Organization for Human Brain Mapping

Natalie Voets and Manzar Ashtari and Christian Beckmann and Christopher Benjamin and Tammie Benzinger and Jeffrey R Binder and Alberto Bizzi and bruce bjornson and Edward F Chang and Linda Douw and Jodie Gawryluk and Karsten Geletneky and Matt Glasser and Haller Sven and Mark Jenkinson and Jorge Jovicich and Eric Leuthardt and Asim Mian and Thomas Nichols and Oiwi Parker Jones and Cyril R Pernet and Puneet Plaha and Monika Polczynska and Cathy J. Price and Geert-Jan Rutten and Michael Scheel and Joshua Shimony and Joanna Sierpowska and Lynne Williams and Ghoufran and Michael M. Zeineh and Andreas Bartsch and Susan Bookheimer

DOI: 10.31219/osf.io/r7u8p

IPSS Study - International Paediatric Stroke Study

We aim to obtain preliminary data from large multi-center studies assessing sub-types, outcomes and current treatments for newborns and children with stroke. Due to the relative rarity of childhood stoke, sufficient numbers of patients to provide the necessary power can only be achieved with multi-center and multi-national approaches. The overall objective is to develop and conduct clinical trials in childhood stroke.

The specific aims are:

Ascertain in a prospective cohort study, the numbers of newborns and children with ischemic stroke, their stroke sub-types and risk factors, their current treatments and outcomes within the participating centers. These data will provide the rationale and feasibility data for the study group to design and implement the initial RCT’s in paediatric stroke as well as other fundable grant proposals.

Develop and institute standardized protocols for (1) diagnosis, (2) investigation of risk factors, (3) antithrombotic therapies and (4) outcome assessment of neonates and children with arterial ischemic stroke and sinovenous thrombosis

Develop standardized data forms and an appropriate database with web-based data entry from multiple study sites.

Submit successful grant applications for additional funding of IPSS multi-centre studies.
This prospective study enrolls newborns and children with ischemic stroke born at or referred to BC Children’s Hospital. These newborns are then followed at 3 and 12 months post stroke.

fMRI Study - Multi-Site Pediatric Network for fMRI Mapping in Childhood Epilepsy

We aim to establish the utility of functional Magnetic Resonance Imaging (fMRI) in identifying atypical language in childhood localization related epilepsy, by using a variety of language paradigms that have already been tested in normal children and patients with epilepsy.

The study objectives include:

To establish the network infrastructure for multi-site collection and management of functional imaging data linked to a database of common assessments and measures

To establish the feasibility of conducting multi-site fMRI by identifying patients with atypical language, and to provide pilot data necessary to conduct a large scale study to compare fMRI findings to invasive methods (IAT, ECS, surgical outcome)

To achieve this goals, an imaging consortium with web based access and central data storage will be established. A multi-centre, cross sectional prospective study will use fMRI to study patients undergoing epilepsy surgery. Clinical data will be collected as part of routine evaluation for chronic epilepsy in children considered for epilepsy surgery.

Honours & Awards

Farley Fellowship (Children's Hospital, Boston), 1992

University of Alberta Alumni Association Award , 1977

Adella Patridge Award for Cardiology (University of Alberta), 1981

Von Meyer Travelling Award (Children's Hospital, Boston), 1991

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