Overview

My research focuses on the application of multi-modality functional neuroimaging methods, which link abnormalities of neurological function to demonstrable alterations of neuroanatomy and neurophysiology, and thereby enhance understanding of neurological disorders in infants, children and young adults with stroke and other brain injuries (e.g., sports concussions), epilepsy and neurodevelopmental disorders. I collaborate with regional, national and international collaborators who seek to evaluate outcomes and enhance neurological care using advanced non-invasive functional neuroimaging methodologies for children.

Publications

Advancing Concussion Assessment in Pediatrics (A-CAP): a prospective, concurrent cohort, longitudinal study of mild traumatic brain injury in children: protocol study.
BMJ open
DOI: 10.1136/bmjopen-2017-017012
PubMed: 28710227
07/2017

Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke RegistryOriginal research article
Pediatr Neurol
DOI: doi: 10.1016/j.pediatrneurol.2017.01.016.
PubMed: 28254555
04/2017

Harnessing Neuroimaging Capability in Pediatric Stroke: Proceedings of the Stroke Imaging Laboratory for Children Workshop
Pediatric Neurology
Nomazulu Dlamini, Max Wintermark, Heather Fullerton, Stephen Strother, Wayne Lee, Bruce Bjornson, Kristin P. Guilliams, Steven Miller, Adam Kirton, Christopher G. Filippi, Alexandra Linds, Rand Askalan, Gabrielle deVeber
DOI: 10.1016/j.pediatrneurol.2017.01.006
04/2017

Epidemiology and Outcomes of Arterial Ischemic Stroke in Children: The Canadian Pediatric Ischemic Stroke Registry.
deVeber GA, Kirton A, Booth FA, Yager JY, Wirrell EC, Wood E, Shevell M, Surmava AM, McCusker P, Massicotte MP, MacGregor D, MacDonald EA, Meaney B, Levin S, Lemieux BG, Jardine L, Humphreys P, David M, Chan AK, Buckley DJ
DOI: 10.1016/j.pediatrneurol.2017.01.016
PubMed: 28254555
01/2017

Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence.
DOI: 10.1161/strokeaha.116.013719
PubMed: 27491741
09/2016

Surface displacement based shape analysis of central brain structures in preterm-born children
Medical Imaging 2016: Biomedical Applications in Molecular, Structural, and Functional Imaging
Amanmeet Garg and Ruth E. Grunau and Karteek Popuri and Steven Miller and Bruce Bjornson and Kenneth J. Poskitt and Mirza Faisal Beg
DOI: 10.1117/12.2216914
03/2016

Risk of Recurrent Arterial Ischemic Stroke in Childhood: A Prospective International Study.
Fullerton HJ, Wintermark M, Hills NK, Dowling MM, Tan M, Rafay MF, Elkind MS, Barkovich AJ, deVeber GA, VIPS Investigators
DOI: 10.1161/strokeaha.115.011173
PubMed: 26556824
01/2016

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis?
Stroke
Wei, F. and Diedrich, K.T. and Fullerton, H.J. and DeVeber, G. and Wintermark, M. and Hodge, J. and Kirton, A. and Dowling, M.M. and Benedict, S.L. and Bernard, T.J. and Fox, C.K. and Friedman, N.R. and Lo, W.D. and Ichord, R.N. and Tan, M.A. and Mackay, M.T. and Hernandez Chavez, M.I. and Humphreys, P. and Jordan, L.C. and Sultan, S.M. and Rivkin, M.J. and Rafay, M.F. and Titomanlio, L. and Kovacevic, G.S. and Yager, J.Y. and Amlie-Lefond, C. and Dlamini, N. and Condie, J. and Yeh, E.A. and Kneen, R. and Bjornson, B.H. and Pergami, P. and Zou, L.P. and Elbers, J. and Abdalla, A. and Chan, A.K. and Farooq, O. and Lim, M.J. and Carpenter, J.L. and Pavlakis, S. and Wong, V.C.N. and Forsyth, R.
DOI: 10.1161/STROKEAHA.115.011331
2016

Risk of Recurrent Arterial Ischemic Stroke in Childhood: A Prospective International Study.
Fullerton HJ and Wintermark M and Hills NK and Dowling MM and Tan M and Rafay MF and Elkind MS and Barkovich AJ and deVeber GA and VIPS Investigators
DOI: 10.1161/STROKEAHA.115.011173
2016

Inflammatory Biomarkers in Childhood Arterial Ischemic Stroke: Correlates of Stroke Cause and Recurrence.
Fullerton HJ and deVeber GA and Hills NK and Dowling MM and Fox CK and Mackay MT and Kirton A and Yager JY and Bernard TJ and Hod EA and Wintermark M and Elkind MS and VIPS Investigators
DOI: 10.1161/STROKEAHA.116.013719
2016

Further Validation of the SIGMAR1 c.151+1G>T Mutation as Cause of Distal Hereditary Motor Neuropathy.
Child neurology open
DOI: 10.1177/2329048x16669912
PubMed: 28503617
2016

Infection, vaccination, and childhood arterial ischemic stroke: Results of the VIPS study.
Fullerton HJ, Hills NK, Elkind MS, Dowling MM, Wintermark M, Glaser CA, Tan M, Rivkin MJ, Titomanlio L, Barkovich AJ, deVeber GA, VIPS Investigators
DOI: 10.1212/wnl.0000000000002065
PubMed: 26423434
10/2015

Neonatal Pain and Infection Relate to Smaller Cerebellum in Very Preterm Children at School Age
Journal of Pediatrics
Ranger, M. and Zwicker, J.G. and Chau, C.M.Y. and Park, M.T.M. and Chakravarthy, M.M. and Poskitt, K. and Miller, S.P. and Bjornson, B.H. and Tam, E.W.Y. and Chau, V. and Synnes, A.R. and Grunau, R.E.
DOI: 10.1016/j.jpeds.2015.04.055
2015

Infection, vaccination, and childhood arterial ischemic stroke: Results of the VIPS study.
Fullerton HJ and Hills NK and Elkind MS and Dowling MM and Wintermark M and Glaser CA and Tan M and Rivkin MJ and Titomanlio L and Barkovich AJ and deVeber GA and VIPS Investigators
DOI: 10.1212/WNL.0000000000002065
2015

Manually segmented template library for 8-year-old pediatric brain MRI data with 16 subcortical structures
J. Med. Imag
Amanmeet Garg and Darren Wong and Karteek Popuri and Kenneth J. Poskitt and Kevin Fitzpatrick and Bruce Bjornson and Ruth E. Grunau and Mirza Faisal Beg
DOI: 10.1117/1.jmi.1.3.034502
PubMed: 26158067
10/2014

The effects of pediatric epilepsy on a language connectome
Human Brain Mapping
Eddin, A.S. and Wang, J. and Wu, W. and Sargolzaei, S. and Bjornson, B. and Jones, R.A. and Gaillard, W.D. and Adjouadi, M.
DOI: 10.1002/hbm.22600
PubMed: 25082062
2014

Arteriopathy diagnosis in childhood arterial ischemic stroke: Results of the vascular effects of infection in pediatric stroke study
Stroke
Wintermark, M. and Hills, N.K. and DeVeber, G.A. and Barkovich, A.J. and Elkind, M.S.V. and Sear, K. and Zhu, G. and Leiva-Salinas, C. and Hou, Q. and Dowling, M.M. and Bernard, T.J. and Friedman, N.R. and Ichord, R.N. and Fullerton, H.J. and Benedict, S.L. and Fox, C.K. and Lo, W.D. and Tan, M.A. and Mackay, M.T. and Kirton, A. and Hernandez Chavez, M.I. and Humphreys, P. and Jordan, L.C. and Sultan, S.M. and Rivkin, M.J. and Rafay, M.F. and Titomanlio, L. and Kovacevic, G.S. and Yager, J.Y. and Amlie-Lefond, C. and Dlamini, N. and Condie, J. and Yeh, A. and Kneen, R. and Bjornson, B.H. and Pergami, P. and Zou, L.P. and Elbers, J. and Abdalla, A. and Chan, A.K. and Farooq, O. and Lim, M.J. and Carpenter, J.L. and Pavlakis, S. and Wong, V.C. and Forsyth, R.
DOI: 10.1161/STROKEAHA.114.007404
PubMed: 25388419
2014

Antithrombotic therapy for secondary stroke prevention in bacterial meningitis in children
Journal of Pediatrics
Boelman, C. and Shroff, M. and Yau, I. and Bjornson, B. and Richrdson, S. and Deveber, G. and Macgregor, D. and Moharir, M. and Askalan, R.
DOI: 10.1016/j.jpeds.2014.06.013
PubMed: 25063717
2014

Cerebellar language mapping and cerebral language dominance in pediatric epilepsy surgery patients
NeuroImage: Clinical
Gelinas, J.N. and Fitzpatrick, K.P.V. and Kim, H.C. and Bjornson, B.H.
DOI: 10.1016/j.nicl.2014.06.016
PubMed: 25379442
2014

Classification of FMRI patterns-A study of the language network segregation in pediatric localization related epilepsy
Human Brain Mapping
Wang, J. and You, X. and Wu, W. and Guillen, M.R. and Cabrerizo, M. and Sullivan, J. and Donner, E. and Bjornson, B. and Gaillard, W.D. and Adjouadi, M.
DOI: 10.1002/hbm.22265
PubMed: 23450847
2014

Invasive procedures in preterm children: Brain and cognitive development at school age
Pediatrics
Vinall, J. and Miller, S.P. and Bjornson, B.H. and Fitzpatrick, K.P.V. and Poskitt, K.J. and Brant, R. and Synnes, A.R. and Cepeda, I.L. and Grunau, R.E.
DOI: 10.1542/peds.2013-1863
PubMed: 24534406
2014

Manually segmented template library for 8-year-old pediatric brain MRI data with 16 subcortical structures
Journal of Medical Imaging
Garg, A. and Wong, D. and Popuri, K. and Poskitt, K.J. and Fitzpatrick, K. and Bjornson, B. and Grunau, R.E. and Beg, M.F.
DOI: 10.1117/1.JMI.1.3.034502
2014

Serial monitoring of CO2 reactivity following sport concussion using hypocapnia and hypercapnia
Brain Injury
Len, T.K. and Neary, J.P. and Asmundson, G.J.G. and Candow, D.G. and Goodman, D.G. and Bjornson, B. and Bhambhani, Y.N.
DOI: 10.3109/02699052.2012.743185
PubMed: 23438354
2013

A decisional space for fMRI pattern separation using the principal component analysis-a comparative study of language networks in pediatric epilepsy
Human Brain Mapping
You, X. and Adjouadi, M. and Wang, J. and Guillen, M.R. and Bernal, B. and Sullivan, J. and Donner, E. and Bjornson, B. and Berl, M. and Gaillard, W.D.
DOI: 10.1002/hbm.22069
2013

Neonatal Pain-Related Stress Predicts Cortical Thickness at Age 7 Years in Children Born Very Preterm
PLoS ONE
Ranger, M. and Chau, C.M.Y. and Garg, A. and Woodward, T.S. and Beg, M.F. and Bjornson, B. and Poskitt, K. and Fitzpatrick, K. and Synnes, A.R. and Miller, S.P. and Grunau, R.E.
DOI: 10.1371/journal.pone.0076702
2013

Cortical basis for dichotic pitch perception in developmental dyslexia
Brain and Language
Partanen, M. and Fitzpatrick, K. and Mädler, B. and Edgell, D. and Bjornson, B. and Giaschi, D.E.
DOI: 10.1016/j.bandl.2012.09.002
2012

Symptomatic neonatal arterial ischemic stroke: the International Pediatric Stroke Study.
Kirton A, Armstrong-Wells J, Chang T, Deveber G, Rivkin MJ, Hernandez M, Carpenter J, Yager JY, Lynch JK, Ferriero DM, International Pediatric Stroke Study Investigators
DOI: 10.1542/peds.2011-1148
PubMed: 22123886
12/2011

Cerebrovascular reactivity impairment after sport-induced concussion
Medicine and Science in Sports and Exercise
Len, T.K. and Neary, J.P. and Asmundson, G.J.G. and Goodman, D.G. and Bjornson, B. and Bhambhani, Y.N.
DOI: 10.1249/MSS.0b013e3182249539
2011

Sub-patterns of language network reorganization in pediatric localization related epilepsy: A multisite study
Human Brain Mapping
You, X. and Adjouadi, M. and Guillen, M.R. and Ayala, M. and Barreto, A. and Rishe, N. and Sullivan, J. and Dlugos, D. and Vanmeter, J. and Morris, D. and Donner, E. and Bjornson, B. and Smith, M.L. and Bernal, B. and Berl, M. and Gaillard, W.D.
DOI: 10.1002/hbm.21066
2011

Cerebrovascular Reactivity Impairment after Sport-Induced Concussion
Medicine & Science in Sports & Exercise
TREVOR K. LEN, J. PATRICK NEARY, GORDON J. G. ASMUNDSON, DAVID G. GOODMAN, BRUCE BJORNSON, YAGESH N. BHAMBHANI
DOI: 10.1249/mss.0b013e3182249539
2011

Antithrombotic treatment in neonatal cerebral sinovenous thrombosis: results of the International Pediatric Stroke Study.
Jordan LC, Rafay MF, Smith SE, Askalan R, Zamel KM, deVeber G, Ashwal S, International Pediatric Stroke Study Group
DOI: 10.1016/j.jpeds.2009.11.061
PubMed: 20149389
05/2010

The role of area V5/MT+ in the centripetal bias in global motion perception
Journal of Vision
D. Giaschi, A. Zwicker, S. A. Young, B. Lee, B. Bjornson
DOI: 10.1167/7.9.751
03/2010

Combined Functional MRI and Diffusion Tensor Imaging Analysis of Visual Motion Pathways
Journal of Neuro-Ophthalmology
Linda J Lanyon, Deborah Giaschi, Simon Au Young, Kevin Fitzpatrick, Lu Diao, Bruce H Bjornson, Jason J S Barton
DOI: 10.1097/wno.0b013e3181a58ef8
06/2009

Use of alteplase in childhood arterial ischaemic stroke: a multicentre, observational, cohort study.
Amlie-Lefond C, deVeber G, Chan AK, Benedict S, Bernard T, Carpenter J, Dowling MM, Fullerton H, Hovinga C, Kirton A, Lo W, Zamel K, Ichord R, International Pediatric Stroke Study
DOI: 10.1016/s1474-4422(09)70106-1
PubMed: 19423401
06/2009

Male predominance in childhood ischemic stroke: findings from the international pediatric stroke study.
Golomb MR, Fullerton HJ, Nowak-Gottl U, Deveber G, International Pediatric Stroke Study Group
DOI: 10.1161/strokeaha.108.521203
PubMed: 18787197
01/2009

Combined functional MRI and diffusion tensor imaging analysis of visual motion pathways
Journal of Neuro-Ophthalmology
Lanyon, L.J. and Giaschi, D. and Young, S.A. and Fitzpatrick, K. and Diao, L. and Bjornson, B.H. and Barton, J.J.S.
DOI: 10.1097/WNO.0b013e3181a58ef8
PubMed: 19491631
2009

Intracranial calcification after cord blood neonatal transplantation for Krabbe disease
Neuropediatrics
Lehman, A.M. and Schultz, K.R. and Poskitt, K. and Bjornson, B. and Keyes, R. and Waters, P.J. and Clarke, L.A. and Everett, R. and McConnell, D. and Stockler, S.
DOI: 10.1055/s-0029-1243189
PubMed: 20135576
2009

Overlapping cortical systems for reading and temporal processing
CANADIAN JOURNAL OF EXPERIMENTAL PSYCHOLOGY-REVUE CANADIENNE DE PSYCHOLOGIE EXPERIMENTALE
PARTANEN, M and EDGELL, D and BJORNSON, B and GIASCHI, D
2009

Conscious visual abilities in a patient with early bilateral occipital damage
Developmental Medicine & Child Neurology
Deborah Giaschi, James E Jan, Bruce Bjornson, Simon Au, Matthew Tata MSc, Christopher J Lyons, Peter KH
DOI: 10.1111/j.1469-8749.2003.tb00888.x
02/2007

Anti-basal ganglia antibodies and acute movement disorder following herpes zoster and streptococcal infections
European Journal of Paediatric Neurology
Basheer, S.N. and Wadsworth, L.D. and Bjornson, B.H.
DOI: 10.1016/j.ejpn.2006.11.001
2007

The role of cortical area V5/MT+ in speed-tuned directional anisotropies in global motion perception
Vision Research
Giaschi, D. and Zwicker, A. and Young, S.A. and Bjornson, B.
DOI: 10.1016/j.visres.2006.12.017
2007

Asymmetrical cortical activation by global motion in children with dyslexia
Journal of Vision
D. Giaschi, V. Edwards, S. A. Young, B. Bjornson
DOI: 10.1167/5.8.848
09/2005

Genotypic heterogeneity and clinical phenotype in triple A syndrome: A review of the NIH experience 2000-2005
Clinical Genetics
Brooks, B.P. and Kleta, R. and Stuart, C. and Tuchman, M. and Jeong, A. and Stergiopoulos, S.G. and Bei, T. and Bjornson, B. and Russell, L. and Chanonine, J.-P. and Tsagarakis, S. and Kalsner, L.R. and Stratakis, C.A.
DOI: 10.1111/j.1399-0004.2005.00482.x
2005

Psychophysical indexes of temporal processing abnormalities in children with developmental dyslexia
Developmental Neuropsychology
Edwards, V.T. and Giaschi, D.E. and Dougherty, R.F. and Edgell, D. and Bjornson, B.H. and Lyons, C. and Douglas, R.M.
DOI: 10.1207/s15326942dn2503_5
2004

Conscious visual abilities in a patient with early bilateral occipital damage.
Giaschi D, Jan JE, Bjornson B, Young SA, Tata M, Lyons CJ, Good WV, Wong PK
DOI: 10.1017/s0012162203001439
PubMed: 14580134
11/2003

Overcoming activation-induced registration errors in fMRI
Proceedings of SPIE - The International Society for Optical Engineering
Orchard, J.J. and Greif, C. and Golub, G.H. and Bjornson, B. and Atkins, M.S.
DOI: 10.1117/12.480849
2003

Simultaneous registration and activation detection for fMRI
IEEE Transactions on Medical Imaging
Orchard, J. and Greif, C. and Golub, G.H. and Bjornson, B. and Atkins, M.S.
DOI: 10.1109/TMI.2003.819294
PubMed: 14606676
2003

Conscious visual abilities in a patient with early bilateral occipital damage
Journal of Vision
Giaschi, D. and Bjornson, B. and Jan, J. and Tata, M. and Young, S.A. and Lyons, C.J. and Good, W.V. and Wong, P.K.H.
DOI: 10.1167/2.7.428
2002

Cerebral Sinovenous Thrombosis in Children
N Engl J Med
DOI: 10.1056/nejm200108093450604
PubMed: 11496852
08/2001

Hemispheric dissociation of verb generation from verb reading: functional MRI of an adolescent with early left MCA infraction
NEUROIMAGE
BJORNSON, B and GIASCHI, D and SLICK, D and CONNOLLY, M and YOUNG, SA
2001

Cerebral sinovenous thrombosis in children
New England Journal of Medicine
DeVeber, G. and Andrew, M. and Adams, C. and Bjornson, B. and Booth, F. and Buckley, D.J. and Camfield, C.S. and David, M. and Humphreys, P. and Langevin, P. and MacDonald, E.A. and Gillett, J.
DOI: 10.1056/NEJM200108093450604
2001

Hemispheric dissociation of verb generation from verb reading: functional MRI of an adolescent with early left MCA infraction
NEUROIMAGE
BJORNSON, B and GIASCHI, D and SLICK, D and CONNOLLY, M and YOUNG, SA
2001

High resolution EEG & seizure localization
NeuroImage
Wong, P.K.H. and Bjornson, B. and Connolly, M. and Steinbok, P. and Young, S.A. and Giaschi, D. and Gregory, D. and Smith, S. and Lee, R. and Man, A. and Cochrane, D.
1999

Non-invasive mapping of sensorimotor cortex in a child with a cavernous angioma: FMRI and high-resolution EEG compared with surgical mapping
NeuroImage
Bjornson, B. and Giaschi, D. and Cochrane, D. and Au Young, S. and Rootman, D. and Boden, C. and Connolly, M. and Poskitt, K. and Boyle, C. and Smith, S. and Akagemi, R. and Wong, P.K.H.
1999

Non-invasive mapping of sensorimotor cortex in a child with a cavernous angioma: FMRI and high-resolution EEG compared with surgical mapping
NeuroImage
Bjornson, B. and Giaschi, D. and Cochrane, D. and Au Young, S. and Rootman, D. and Boden, C. and Connolly, M. and Poskitt, K. and Boyle, C. and Smith, S. and Akagemi, R. and Wong, P.K.H.
1999

High resolution EEG & seizure localization
NeuroImage
Wong, P.K.H. and Bjornson, B. and Connolly, M. and Steinbok, P. and Young, S.A. and Giaschi, D. and Gregory, D. and Smith, S. and Lee, R. and Man, A. and Cochrane, D.
1999

Dichotic pitcha new stimulus distinguishes normal and dyslexic auditory function
NeuroReport
Robert F. Dougherty and Max S. Cynader and Bruce H. Bjornson and Dorothy Edgell and Deborah E. Giaschi
DOI: 10.1097/00001756-199809140-00015
PubMed: 9804305
09/1998

Comparison of visual activation measured by fMRI and high resolution EEG
NeuroImage
Dougherty, R.F. and Au Young, S.M.W. and Giaschi, D.E. and Bjornson, B.H. and Wong, P.K.H.
1998

Dichotic pitch: A new stimulus distinguishes normal and dyslexic auditory function
NeuroReport
Dougherty, R.F. and Cynader, M.S. and Bjornson, B.H. and Edgell, D. and Giaschi, D.E.
1998

Comparison of visual activation measured by fMRI and high resolution EEC
NeuroImage
Dougherty, R.F. and Au Young, S.M.W. and Giaschi, D.E. and Bjornson, B.H. and Wong, P.K.H.
1998

Basal ganglia infarction associated with HHV-6 infection
Archives of Disease in Childhood
D. W Webb, B. H Bjornson, M. A Sargent, J. Hukin, E. E Thomas
DOI: 10.1136/adc.76.4.362
04/1997

Basal ganglia infarction associated with HHV-6 infection
Archives of Disease in Childhood
Webb, D.W. and Bjornson, B.H. and Sargent, M.A. and Hukin, J. and Thomas, E.E.
1997

In search of the best psychophysical indicator of an M-stream deficit in developmental dyslexia
Investigative Ophthalmology and Visual Science
Dougherty, R.F. and Giaschi, D.E. and Bjornson, B.H. and Chamul, S.L. and Edgcll, D. and Lyons, C.J.
1997

Basal ganglia infarction associated with HHV-6 infection
Archives of Disease in Childhood
Webb, D.W. and Bjornson, B.H. and Sargent, M.A. and Hukin, J. and Thomas, E.E.
PubMed: 9166034
1997

In search of the best psychophysical indicator of an M-stream deficit in developmental dyslexia
Investigative Ophthalmology and Visual Science
Dougherty, R.F. and Giaschi, D.E. and Bjornson, B.H. and Chamul, S.L. and Edgcll, D. and Lyons, C.J.
1997

Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy.
Packard AB, Roach PJ, Davis RT, Carmant L, Davis R, Riviello J, Holmes G, Barnes PD, O'Tuama LA, Bjornson B, Treves ST
PubMed: 8965177
07/1996

Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy
Journal of Nuclear Medicine
Packard, A.B. and Roach, P.J. and Davis, R.T. and Carmant, L. and Davis, R. and Riviello, J. and Holmes, G. and Barnes, P.D. and O'Tuama, L.A. and Bjornson, B. and Treves, S.T.
1996

Ictal and interictal technetium-99m-bicisate brain SPECT in children with refractory epilepsy
Journal of Nuclear Medicine
Packard, A.B. and Roach, P.J. and Davis, R.T. and Carmant, L. and Davis, R. and Riviello, J. and Holmes, G. and Barnes, P.D. and O'Tuama, L.A. and Bjornson, B. and Treves, S.T.
PubMed: 8965177
1996

Brain
Pediatric Nuclear Medicine
L. A. O’Tuama, B. Bjornson, H. Chugani, S. T. Treves
DOI: 10.1007/978-1-4757-4205-3_6
1995

Computed Tomography Imaging in Children with Head Trauma: Utilization and Appropriateness from a Quality Improvement Perspective
Infection Control and Hospital Epidemiology
Montserrat Vera, Gary R. Fleisher, Patrick D. Barnes, Bruce H. Bjornson, Elizabeth N. Allred, Donald A. Goldmann
DOI: 10.2307/30145525
08/1993

Computed tomography imaging in children with head trauma: utilization and appropriateness from a quality improvement perspective
Infection Control & Hospital Epidemiology
Vera, M. and Fleisher, G.R. and Barnes, P.D. and Bjornson, B.H. and Allred, E.N. and Goldmann, D.A.
DOI: 10.1086/646787
PubMed: 8376744
1993

Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias.
O'Tuama LA, Urion DK, Janicek MJ, Treves ST, Bjornson B, Moriarty JM
PubMed: 1383478
10/1992

Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias
Journal of Nuclear Medicine
O'Tuama, L.A. and Urion, D.K. and Janicek, M.J. and Treves, S.T. and Bjornson, B. and Moriarty, J.M.
1992

Regional cerebral perfusion in Landau-Kleffner syndrome and related childhood aphasias
Journal of Nuclear Medicine
O'Tuama, L.A. and Urion, D.K. and Janicek, M.J. and Treves, S.T. and Bjornson, B. and Moriarty, J.M.
PubMed: 1383478
1992

Research

IPSS Study - International Paediatric Stroke Study
We aim to obtain preliminary data from large multi-center studies assessing sub-types, outcomes and current treatments for newborns and children with stroke. Due to the relative rarity of childhood stoke, sufficient numbers of patients to provide the necessary power can only be achieved with multi-center and multi-national approaches. The overall objective is to develop and conduct clinical trials in childhood stroke.

The specific aims are:

Ascertain in a prospective cohort study, the numbers of newborns and children with ischemic stroke, their stroke sub-types and risk factors, their current treatments and outcomes within the participating centers. These data will provide the rationale and feasibility data for the study group to design and implement the initial RCT’s in paediatric stroke as well as other fundable grant proposals.

Develop and institute standardized protocols for (1) diagnosis, (2) investigation of risk factors, (3) antithrombotic therapies and (4) outcome assessment of neonates and children with arterial ischemic stroke and sinovenous thrombosis

Develop standardized data forms and an appropriate database with web-based data entry from multiple study sites.

Submit successful grant applications for additional funding of IPSS multi-centre studies.
This prospective study enrolls newborns and children with ischemic stroke born at or referred to BC Children’s Hospital. These newborns are then followed at 3 and 12 months post stroke.

fMRI Study - Multi-Site Pediatric Network for fMRI Mapping in Childhood Epilepsy
We aim to establish the utility of functional Magnetic Resonance Imaging (fMRI) in identifying atypical language in childhood localization related epilepsy, by using a variety of language paradigms that have already been tested in normal children and patients with epilepsy.

The study objectives include:

To establish the network infrastructure for multi-site collection and management of functional imaging data linked to a database of common assessments and measures

To establish the feasibility of conducting multi-site fMRI by identifying patients with atypical language, and to provide pilot data necessary to conduct a large scale study to compare fMRI findings to invasive methods (IAT, ECS, surgical outcome)

To achieve this goals, an imaging consortium with web based access and central data storage will be established. A multi-centre, cross sectional prospective study will use fMRI to study patients undergoing epilepsy surgery. Clinical data will be collected as part of routine evaluation for chronic epilepsy in children considered for epilepsy surgery.

Honours & Awards

Farley Fellowship (Children's Hospital, Boston), 1992

University of Alberta Alumni Association Award , 1977

Adella Patridge Award for Cardiology (University of Alberta), 1981

Von Meyer Travelling Award (Children's Hospital, Boston), 1991

Research Group Members

Justin Dragoman