We can provide species identification for members of the Burkholderia cepacia complex of bacteria. We also can provide strain typing information, as well as identifications for other species which grow on Burkholderia cepacia selective agar and for which the preliminary identification might be equivocal: such as B. gladioli, Ralstonia species, Pandoraea species and others. Most of our work is for cystic fibrosis clinics, however we are very happy to provide assistance to anyone else requiring identification of these bacteria.
We employ various approaches to determine how DNA methylation and chromatin protein modifications are regulated, how they interact with the underlying genetic sequence to affect which genes are expressed in which cells, and how changes to these epigenetic marks can affect human development and lifelong health trajectories. Together, the research in our lab bridges the molecular mechanisms of epigenetic regulation and the social and environmental determinants of human health to develop a comprehensive understanding of early life.
We are systematically dissecting the molecular mechanisms of the neonatal and infant response to infection or vaccination. Based on that knowledge, we are identifying immune modulators that help protect newborns and infants.
The OPSiP study (short for "Oral Probiotic Supplementation in Pregnancy to Reduce Group B Streptococcus Colonization") is a randomized controlled trial (RCT) that is recruiting 450 participants in Vancouver, British Columbia.
Pocket Doc for Pneumonia is a low-cost smartphone tool that uses a light-weight sensor and a data-driven app to assess a child’s vital signs and overall condition, deliver an accurate diagnosis and recommend inexpensive, life-saving treatments such as antibiotics, oxygen and fluids.
Mini Med School is an award-winning health science youth outreach and public education program that's been held 21 times since 2003. This fall’s Mini Med School is transitioning to an all-virtual learning platform and focusing on the microbiome. In addition to Mini Med School Live for Grade 10 to 12 students, there's a Mini Med School On-Demand, which is open to everyone.
BC School Sports, the governing organization for school sports in the province, has mandated a BC Children’s Hospital-based concussion education training module for its members who work with young athletes. Now those who supervise secondary school sports will be better prepared to prevent, respond to, and manage concussions in teens when these activities resume this fall.
On World Sepsis Day — September 13, 2020 — the Global Sepsis Alliance (GSA) and the World Health Organization (WHO) are urging all health systems, policymakers, healthcare workers, researchers, and civilians to develop a concerted effort on sepsis prevention, diagnosis, and management to save lives.
A new study, published this week in Science Translational Medicine, further refines a potential new treatment that can prevent transplant rejection in kids and adults without leaving them vulnerable to infection.
We believe there’s nothing we can’t do with your support. It can take years to turn scientific breakthrough into new interventions and treatments. Funding helps speed the pace of change. When given the resources, we can bring transformative therapies – and hope – out of the laboratory and into the clinic to save and improve children’s lives.