• Cooper, Anthony

    Titles

    Investigator, BC Children's Hospital
    Clinical Assistant Professor, Division of Pediatric Orthopaedic Surgery, Department of Orthopaedics, University of British Columbia

    Degrees / Designations

    MBChB, FRCS

    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    Phone
    604-875-2642
    Fax
    604-875-2275
    Lab Phone
    604-875-2000 ext. 6008
    Assistant
    Susan Ramiscal
    Assistant Phone
    604-875-2642
    Mailing Address

    BC Children's Hospital
    Room 1D64 
    4480 Oak Street
    Vancouver, BC V6H 3V4

    Affiliate Websites
    Research Areas
    • Paediatric Bone Health and Mobility
    • Limb Deformity
    • Limb Reconstruction
    • Paediatric Hip Disorders
    • Bone Tumours
    • Patient-Reported Outcomes
    • Quality of Life
    Summary

    My research interests range from studies involving paediatric hip, lower limbs, feet, trauma and bone tumours. I am specifically interested in advancing research around paediatric bone health and mobility. In addition to looking at the clinical outcomes, I am also interested in looking at the outcomes reported directly by the patients or caregivers of patients, specifically their quality of life. By studying these outcomes, I am aiming to look at the effectiveness of treatments I use in clinic and to explore ways to improve the quality of life of my patients. I also collaborate with biomechanical engineers to generate computerised models of the hip in order to imitate different deformities around the hip joint.

    Current Projects

    Health-related Quality of Life in Children with Lower Limb Deficiency

    Objectives: a) To develop and validate a patient-reported quality of life tool for children with lower limb deficiency; b) To establish the baseline health-related quality of life in these children using the newly developed tool; c) To investigate the quality of life of caregivers of children with lower limb deficiency.

    Multicentre Pin Site Infection Study

    Objective: To measure and document pin site infection rate and pin site care across Canada, US and UK through a multi-centre pin site infection database. This study involving ten surgeons (BCCH being the primary site) across various sites will provide important information for limb lengthening and reconstruction services across the world, as well as parents/primary caregivers of children in external fixation devices (EFDs). By identifying the factors contributing to pin site infections, this study will take another step towards improving clinical care for children in EFDs.

    Preventative Multimodal Analgesia for Children Undergoing Lower Limb Reconstruction with External Fixators: A Prospective Study of Postoperative Pain

    Objective: To assess the peri-operative analgesia regimen that has been previously developed for children undergoing limb reconstruction surgery at BC Children’s Hospital, during the acute and long-term post-operative recovery phase. This study is being conducted in collaboration with the Department of Anesthesiology, Pharmacology & Therapeutics.

    Simple Bone Cysts in Kids - A multi-centre randomized clinical trial

    Objective: To compare the effectiveness of two common treatments used by orthopaedic surgeons to treat simple bone cysts. This study will provide Level I evidence comparing the effectiveness of two treatment interventions for SBC in pediatric patients: 1) curettage with puncture, and 2) curettage with puncture and injection of Vitoss morsels. 

    Primary Site – Hospital for Sick Kids, Toronto

    Weight-bearing MRI in Perthes Disease: A Pilot Study

    Objective: To evaluate femoral head deformity and extrusion in Legg–Calvé–Perthes Disease using functional weight-bearing MRI.

    Next Generation Sequencing (NGS) in Rare Disorders in Orthopaedics

    Objective: To identify rare disorders in orthopaedics using NGS. This study is collaboration with the Department of Biochemical Diseases.

    Limb Deficiencies – Development of a Care Map for Affected Families

    Objective: To understand the healthcare experiences of parents who have children with congenital limb deficiencies, specifically in terms of the level of emotional support and information that they have received. This project, being done in collaboration with the Department of Medical Genetics, may help us develop a care map in order to strengthen parental support systems for affected families.

    Selected Publications

    1. Jones CE, Cooper AP, Doucette J, Buchan LL, Wilson DR, Mulpuri K, d’Entremont AG. Relationships between severity of deformity and impingement in slipped capital femoral epiphysis. J Pediatr Orthop. 2017 Jun 1;37(4):272-8.

    2. Chhina H, Klassen A, Kopec J, Park S, Fortes C, Cooper A. Quality of life of children with lower limb deformities: A systematic review of patient-reported outcomes and development of a preliminary conceptual framework. Journal of Limb Lengthening & Reconstruction. 2017 Jan 1; 3(1):19.

    3. Basheer SZ, Cooper AP, Balasubramanian B, Maheshwari R, Madan SS. Arthroscopic treatment of femoroacetabular impingement following slipped capital femoral epiphysis. The Bone and Joint Journal. 2016 Jan; 98-B (1):21-7.

    4. d’Entremont AG, Cooper AP, Johari A, Mulpuri K.  What Clinimetric Evidence Exists for Using Hip-specific Patient-reported Outcome Measures in Pediatric Hip Impingement? Clinical Orthopaedics and Related Research. 2015 Apr; 473(4):1361-1367.

    5. Cooper AP, Evans OG, Ali F M, Flowers M. A novel method for assessing post-operative femoral head reduction in developmental dysplasia of the hip. Journal of Children’s Orthopaedics. 2014 Aug; 8(4): 319-324.

    6. Cooper AP, Doddabasappa S, Mulpuri K. Evidence Based Management of Developmental Dysplasia of the Hip. Orthopaedic Clinics of North America. 2014 Jul; 45(3): 341-354.

    7. Cooper AP, Chhina H, Howren A, Alvarez C.The contralateral foot in children with unilateral clubfoot, is the unaffected side normal? Gait and Posture. 2014 Jul; 40(3):375-380.

    8. Cooper AP, Salih S, Geddis C, Foster P, Fernandes JA, Madan SS. The oblique plane deformity in slipped capital femoral epiphysis. Journal of Children’s Orthopaedics. 2014 March; 8(2):121-127.

    9. Cooper AP, Ali AA. Rotator Cuff Tears (Review Article). Surgery. 2013; 31(4): 168-171.

    10. Cooper AP, Davies AG, Fernandes JA, Madan SS. The treatment of severe slipped capital femoral epiphysis via the Ganz surgical dislocation and anatomical reduction: a prospective study. The Bone and Joint Journal. 2013; 95-B 424-429.

    Grants

    Title: Development of a Patient Reported Quality of Life Questionnaire for Children with Lower Limb Deformities
    Funding Agency: Canadian Orthopaedic Research Legacy (CORL)
    Year: 2017-2019

    Title: Paediatric Limb Reconstruction
    Funding Agency: CFRI Investigator Grant Award Program (IGAP)
    Year: 2016-2021 

    Title: Evaluating the Accuracy of the Paley Multiplier Method for Predicting Limb Length Discrepancy in Populations with Vascular Anomalies
    Funding Agency: UBC Plastic Surgery Academic Grant
    Year: 2016-2017 

    Title: Exome Sequencing in Congenital Pseudarthrosis of Tibia
    Funding Agency: Rare Disease Foundation
    Year: 2016-2017 

    Title: Multi-centre Pin Site Infection Study
    Funding Agency: Pediatric Orthopedics Society of North America (POSNA)
    Year: 2016-2017 

    Title: Development and validation of patient-reported outcome instrument for children with lower limb deformities
    Funding Agency: Orthopaedics Research Excellence Fund, UBC
    Year: 2015-2017

    Title: Screw trajectory in different femoral neck geometries in slipped capital femoral epiphysis: a geometrical modeling study
    Funding Agency: Rare Disease Foundation
    Year: 2014-2015 

    Title: Use of functional weight bearing MRI to evaluate femoral head deformity and extrusion in Legg-Calve-Perthes Disease: a pilot study
    Funding Agency: iACT Trainee Clinical Investigator Seed Grant Competition, CFRI
    Year: 2014-2015 

    Title: Accuracy of deformity measurement in slipped capital femoral epiphysis: a geometrical modeling study
    Funding Agency: Rare Disease Foundation
    Year: 2014-2015 

    Title: Effect of femoral epiphysis position and pin location on impingement in SCFE: a geometrical modeling study
    Funding Agency: Rare Disease Foundation
    Year: 2014-2015

    Honours & Awards
    • Investigator Grant Award, CFRI, 2016
    • Limb Lengthening and Reconstruction Society Traveling Fellowship, 2016
    • Getty Plate for best academic project 2011 (Runner up)
    • Best Podium Presentation at the Combined British Society of Children’s Orthopaedic Surgeons/British Limb Reconstruction Society 2011 (Runner up)
    • Getty Plate for best academic project 2009
    • Honours from Harvard Medical School in Vascular Surgery Elective Internship
    • Honours points in: Biochemistry, Laboratory and Scientific medicine
    • Dora Ratcliffe Medical Elective Award
    Research Group Members

    Research Manager:

    • Harpreet Chhina

    Clinical Fellows:

    • James McCammon (July 2016 – 2017)
    • Ashlee Dobbe (July 2015 - 2016)
    • Lori Anne Archer (July 2015 - 2016)
    • Alex Aarvold (July 2014 - 2015)

    Co-op Students:

    • Angela Eugenio (May 2016 – August 2017)
    • Sujin Park (September 2015 – April 2016)
    • Cadi Fortes (January – August 2015)

    UBC Medical Students:

    • Aresh Sepehri
    • Cindy Ding
    • Warren Koo
    • Victoria McCutcheon
    • Angela Ji