• Boelman, Cyrus

    Investigator, BC Children's Hospital

    Clinical Assistant Professor, Division of Neurology, Department of Pediatrics, University of British Columbia 

    Degrees / Designations
    Primary Area of Research
    Childhood Diseases
    Secondary Area(s) of Research
    Lab Phone
    Mailing Address
    BC Children`s Hospital
    Room K3-150 

    4480 Oak Street
    Vancouver, BC V6H 3V4

    Affiliate Websites
    Research Areas
    • Pediatric Neurology 
    • Epilepsy and Epilepsy Genetics
    Research focuses primarily on Epilepsy in the pediatric population, as well as epilepsy genetics.
    Current Projects
    The Personalized Medicine in the Treatment of Epilepsy: 

    Identification of Genes Predisposing to the disease and to resistance to anti-epileptic treatments study is looking to identify genetic mutations responsible for various forms of epilepsy, as well as to understand the impact of genetic analysis and whole genome sequencing which will be used to study the participant's genes or their genome. This can lead to a better understanding of the disease and enable earlier diagnosis, as well as develop understanding of the genetic factors involved in anti-epileptic medication response at a personalized level.

    Selected Publications

    Jaffer F, Avbersek A, Vavassori R, Fons C, Campistol J, Stagnaro M, De Grandis E, Veneselli E, Rosewich H, Gianotta M, Zucca C, Ragona F, Granata T, Nardocci N, Mikati M, Helseth AR, Boelman C, Minassian BA, Johns S, Garry SI, Scheffer IE, Gourfinkel-An I, Carrilho I, Aylett SE, Parton M, Hanna MG, Houlden H, Neville B, Kurian MA, Novy J, Sander JW, Lambiase PD, Behr ER, Schyns T, Arzimanoglou A, Cross JH, Kaski JP, Sisodiya SM. Faulty cardiac repolarization reserve in alternating hemiplegia of childhood broadens the phenotype. 2015. Brain. 138(10):2859-74

    Akiyama T, Akiyama M, Kobayashi K, Okanishi T, Boelman CG, Nita DA, Ochi A, Go CY, Snead OC 3rd, Rutka JT, Drake JM, Chuang S, Otsubo H. Spatial relationship between fast and slow components of ictal activities and interictal epileptiform discharges in epileptic spasms. 2015. Clin Neurophysiol. 126(9):1684-91

    Boelman C, Lagman-Bartolome AM, MacGregor DL, McCabe J, Logan WJ, Minassian BA. Identical ATP1A3 mutation causes alternating hemiplegia of childhood and rapid-onset dystonia parkinsonism phenotypes. 2014. Pediatr Neurol. 51(6)850-3

    Okanishi T, Akiyama T, Tanaka S, Mayo E, Mitsutake A, Boelman C, Go C, Snead OC 3rd, Drake J, Rutka J, Ochi A, Otsubo H. Interictal high frequency oscillations correlating with seizure outcome in patients with widespread epileptic networks in tuberous sclerosis complex. 2014. Epilepsia. 55(10):1602-10

    Sato Y, Doesburg SM, Wong SM, Boelman C, Ochi A, Otsubo H. Preictal surrender of post-spike slow waves to spike-related high-frequency oscillations (800-200Hz) is associated with seizure initiation. 2014. Epilepsia. 55(9):1399-405

    Boelman C, Shroff M, Yau I, Bjornson B, Richrdson S, deVeber G, MacGregor D, Moharir M, Askalan R. Antithrombotic therapy for secondary stroke prevention in bacterial meningitis in children. 2014. J Pediatr. 165(4):799-806

    Honours & Awards
    Research Group Members