• Amed, Shazhan

    Titles

    Investigator, BC Children's Hospital

    Clinical Associate Professor, Division of Endocrinology & Diabetes, Department of Pediatrics, University of British Columbia

    Affiliate of the Centre for Health Services and Policy Research, University of British Columbia

    Degrees / Designations
    M.Sc., MD
    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    Phone
    604-875- 2000 ext. 4803
    Fax
    604-875-3231
    Lab Phone
    Mailing Address

    BC Children's Hospital
    Room K4-213
    4480 Oak Street
    Vancouver, BC V6H 3V4

    Affiliate Websites
    Research Areas
    • The epidemiology and prevention of type 2 diabetes in children
      Innovative modes of health service delivery to children with chronic disease
    • The prevention of childhood obesity through community engagement and participatory research
    • Evaluation of public health initiatives
    Summary

    My research involves the treatment and prevention childhood obesity and diabetes. As rates of childhood obesity increase, type 2 diabetes in children, a disease that was previously seen only in the adults, will continue to increase. Obesity is the single most important risk factor for the development of type 2 diabetes and therefore, I am interested in developing and evaluating community-based programs designed to prevent childhood obesity. Also, I am interested in developing and evaluating innovative ways to provide the health services necessary for children with diabetes in order to optimize their care and prevent long term complications of this disease.

    Current Projects

    I recently completed a national surveillance study for Non-type 1 diabetes mellitus in Canadian children <18 years of age. This study will provide the minimum incidence of type 2 diabetes mellitus (T2DM) in Canadian children allowing for researchers and policy makers to evaluate future trends as well as to focus prevention programs for T2DM and childhood obesity. The results of this study will be published in Diabetes Care in the upcoming months.

    One of the most striking findings in the national surveillance study for type 2 diabetes was that 95% of Canadian children with T2DM are obese. Therefore, obesity is the single most important risk factor for T2DM. As a result, I am currently leading SCOPE: Sustainable Childhood Obesity Prevention through Community Engagement, a project rooted in the principles of community based participation. SCOPE is a community-based, multi-sectoral childhood obesity prevention project that addresses the mid- and up-stream determinants of health and incorporates the unique characteristics of BC populations. SCOPE will be piloted in the cities of Prince George and Abbotsford.

    I am also working closely with Child Health BC to develop a provincial pediatric diabetes program in British Columbia. Recognizing the importance of evaluating and reporting the impact of new models of care, I will use existing provincial and national databases to determine if this provincial pediatric model of diabetes care will improve clinical (i.e. diabetes control, reduction of complications) and non-clinical outcomes (i.e. school performance, psychosocial outcomes) in children with diabetes.

    Selected Publications
    Published Refereed Papers:

    Amed S, Nuernberger K, McCrea P, Reimer K, Krueger H, Aydede SK, Ayers D, Collet JP. Adherence to Clinical Practice Guidelines in the Management of Children, Youth and Young Adults with Type 1 Diabetes-A Prospective Population Cohort Study J Pediatr. 2013 Mar 21. doi:pii: S0022-3476(13)00191-1. 10.1016/j.jpeds.2013.01.070. [Epub ahead of print]

    Amed S, Dean HJ, Sellers EAC, Panagiotopoulos D, Shah BR, Booth GL, et al. Risk Factors for Medication Induced Diabetes and Type 2 Diabetes. Journal of Pediatrics. 2011. (published online ahead of print). PMID: 21353243

    Amed S, Vanderloo S, Metzger D, Collet JP, Reimer K, McCrae P, Johnson J. Validation of Diabetes Case Definitions using Administrative Claims Data. Diabetic Medicine. 2011; 28(4):424-427. PMID: 21392063

    Amed S, Dean HJ, Panagiotopoulos D, Sellers EAC, Hadjiyanakis S, Laubscher TA, et al. Type 2 Diabetes, Medication-Induced Diabetes, and Monogenic Diabetes in Canadian Children: A Prospective National Surveillance Study. Diabetes Care 2010; 33(4): 786-91. PMID: 20067956

    Amed S, Daneman D, Mahmud FH, Hamilton, J. Type 2 Diabetes in Children and Adolescents. Expert Review Cardiovasc Ther. 2010. Mar;(8):393-406.

    Amed S, Delvin E, Hamilton J. Variation in Growth Hormone Immunoassays in Clinical Practise in Canada. Hormone Research. 2008; 69(5):290-94. PMID: 18259108

    Amed S. CPSP Highlight: Unraveling the risk factors for non-type 1 diabetes in children. Paediatric Child Health 2006; 11(8):506. PMID: 19030318

    Published Contributions to a Collective Work and Book Chapters:
    Amed S, Hamilton J. When Sugar is not so sweet: Diabetes and Metabolic Syndrome. In: Turner Syndrome: Across the Lifespan. Editors: Hamilton J, Hozjan I; Castlemore Graphics, Brampton, ONT; pp 135-45; 2008.

    Amed S, Dean H, Hamilton J. Unraveling non-type 1 diabetes mellitus in childhood. 2006.

    Amed S, Perlman K, Daneman D. Hypoglycaemia in people with type 1 diabetes mellitus. BMJ Learning. 2007.

    Research Reports or Reports Produced for the Government:
    Amed S, Nuernberger K, McCrea P, Reimer J, Vanderloo S, et al. Status Report on Pediatric Diabetes Program. 2010.

    Amed S. Diabetes in Canada: Chapter 6 – Diabetes in Children and Youth, Part 2: Type 2 Diabetes. Public Health Agency of Canada. Submitted for publication.

    Grants

    CIHR Operating Grant: Knowledge to Action - Project: "Tele-SCOPE - Translation, Evaluation and Learnings Exchanged for Sustainable Childhood Obesity Prevention Through Community Engagement."

    Honours & Awards

    Canucks for Kids Fund Catalyst Grant- 2013

    Rookie of the Year, Department Of Pediatrics, BC Children’s Hospital- 2009

    Perls Teaching Award, Department Of Pediatrics, The Hospital For Sick Children —2008

    Restracomp Fellowship Appointment—2007/08
    Salary support during a second year of research fellowship in Paediatric Endocrinology
    Amount: $40,000

    Hoffman Laroche Canadian Paediatric Endocrinology Fellowship Research Award — 2006/07
    Salary support during a year of research fellowship in Paediatric Endocrinology
    Amount: $60,000

    Canadian Society For Clinical Investigation Canadian Institutes Of Research (Csci/Cihr) Resident Research Prize —2004

    Pediatric Resident Regional Research Competition — Winner 2004

    Pediatric Resident National Research Competition — Winner 2004

    Resident Clinical Teaching Award, Child Health at the Health Sciences Center and University of Manitoba — 2003-2004

    Resident Teaching Award, University of Manitoba — 2003-2004

    Research Group Members