Overview

I am involved in diverse studies that include defining clinically relevant pharmacodynamic endpoints for drugs used in paediatric anaesthetic and perioperative care, and providing feedback on aspects of quality of intraoperative care, with the common goal of improving patients' experiences & safety.

Examples of such work include: examining the effects of anaesthetic drugs on myocardial repolarization; investigating relationships between anesthetic pharmacodynamics and pharmacogenetics; exploring relationships between intraoperative homeostasis and post-operative outcomes; contributing to and leading the set-up of multi-centre registries.

Publications

Caudal and Intravenous Anesthesia Without Airway Instrumentation for Laparoscopic Inguinal Hernia Repair in Infants: A Case Series
A&A practice
Krishnan, P. and Whyte, S.D. and Baird, R. and Malherbe, S.
DOI: 10.1213/XAA.0000000000001251
2020

Using physiological monitoring data for performance feedback: an initiative using thermoregulation metrics.
Görges M and West NC and Whyte SD
DOI: 10.1007/s12630-016-0762-3
PubMed: 27785761
03/2017

Preoperative warming and undesired surgical and anesthesia outcomes in pediatric spinal surgery-a retrospective cohort study.
Görges M and West NC and Cheung W and Zhou G and Miyanji F and Whyte SD
DOI: 10.1111/pan.12939
PubMed: 27312044
09/2016

The safety of modern anesthesia for children with long QT syndrome.
Whyte SD and Nathan A and Myers D and Watkins SC and Kannankeril PJ and Etheridge SP and Andrade J and Collins KK and Law IH and Hayes J and Sanatani S
DOI: 10.1213/ane.0000000000000389
PubMed: 25076102
10/2014

ACS national surgical quality improvement program: targeting quality improvement in Canadian pediatric surgery.
Skarsgard ED and Bedford J and Chan T and Whyte S and Afshar K
DOI: 10.1016/j.jpedsurg.2014.02.047
PubMed: 24851748
05/2014

Pediatric Airway Management in COVID-19 Patients: Consensus Guidelines from the Society for Pediatric Anesthesia's Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society
Anesthesia and Analgesia
Matava, C.T. and Kovatsis, P.G. and Lee, J.K. and Castro, P. and Denning, S. and Yu, J. and Park, R. and Lockman, J.L. and Von Ungern-Sternberg, B. and Sabato, S. and Lee, L.K. and Ayad, I. and Mireles, S. and Lardner, D. and Whyte, S. and Szolnoki, J. and Jagannathan, N. and Thompson, N. and Stein, M.L. and Dalesio, N. and Greenberg, R. and McCloskey, J. and Peyton, J. and Evans, F. and Haydar, B. and Reynolds, P. and Chiao, F. and Taicher, B. and Templeton, T. and Bhalla, T. and Raman, V.T. and Garcia-Marcinkiewicz, A. and Gálvez, J. and Tan, J. and Rehman, M. and Crockett, C. and Olomu, P. and Szmuk, P. and Glover, C. and Matuszczak, M. and Galvez, I. and Hunyady, A. and Polaner, D. and Gooden, C. and Hsu, G. and Gumaney, H. and Pérez-Pradilla, C. and Kiss, E.E. and Theroux, M.C. and Lau, J. and Asaf, S. and Ingelmo, P. and Engelhardt, T. and Herviás, M. and Greenwood, E. and Javia, L. and Disma, N. and Yaster, M. and Fiadjoe, J.E.
DOI: 10.1213/ANE.0000000000004872
2020

Effects of Dexmedetomidine on Blood Glucose and Serum Potassium Levels in Children Undergoing General Anesthesia: A Secondary Analysis of Safety Endpoints During a Randomized Controlled Trial
Anesthesia and analgesia
Görges, M. and Poznikoff, A.K. and West, N.C. and Brodie, S.M. and Brant, R.F. and Whyte, S.D.
DOI: 10.1213/ANE.0000000000004154
2019

Effects of Dexmedetomidine on Myocardial Repolarization in Children Undergoing General Anesthesia: A Randomized Controlled Trial
Anesthesia and analgesia
Görges, M. and Sherwin, E.D. and Poznikoff, A.K. and West, N.C. and Brodie, S.M. and Whyte, S.D.
DOI: 10.1213/ANE.0000000000004135
2019

Integrating intraoperative physiology data into outcome analysis for the ACS Pediatric National Surgical Quality Improvement Program
Paediatric Anaesthesia
Görges, M. and Afshar, K. and West, N. and Pi, S. and Bedford, J. and Whyte, S.D.
DOI: 10.1111/pan.13531
2019

Audit and feedback: to tell or not to tell? That is not the question,Audit et rétroaction: dire ou ne pas dire? Telle n’est pas la question
Canadian Journal of Anesthesia
Whyte, S.
DOI: 10.1007/s12630-018-1206-z
2018

A survey of practice in the anesthetic management of adolescent idiopathic scoliosis spine fusion by the North American Pediatric Spine Anesthesiologists Collaborative
Pediatric Anesthesia
Laura E. Gilbertson and Wallis T. Muhly and Michael C. Montana and Vidya Chidambaran and Sabina DiCindio and Kesavan Sadacharam and Robert T. Wilder and Simon D. Whyte and Alan Hifko and Paul D. Sponseller and David D. Frankville
DOI: 10.1111/pan.14895
04/2024

Pediatric anesthesia in North America
Pediatric Anesthesia
Ilavajady Srinivasan and Simon Whyte and Katherine Bailey and Tiffany Antrobus and Karisha Hinkson-LaCorbinière and Timothy W. Martin and Joseph P. Cravero and Linda J. Mason
DOI: 10.1111/pan.14872
03/2024

An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation
JMIR Pediatrics and Parenting
Michael D Wood and Nicholas C West and Christina Fokkens and Ying Chen and Kent C Loftsgard and Krystal Cardinal and Simon D Whyte and Elodie Portales-Casamar and Matthias Görges
DOI: 10.2196/46785
11/2023

An Individualized Postoperative Pain Risk Communication Tool for Use in Pediatric Surgery: Co-Design and Usability Evaluation (Preprint)
Michael D Wood and Nicholas C West and Christina Fokkens and Ying Chen and Kent C Loftsgard and Krystal Cardinal and Simon D Whyte and Elodie Portales-Casamar and Matthias Görges
DOI: 10.2196/preprints.46785
02/2023

Anesthesia and neurodevelopment after 20 years: where are we now and where to next?,Anesthésie et neurodéveloppement, 20 ans après : regard actuel et perspectives d’avenir
Canadian Journal of Anesthesia
Bailey, K.M. and Whyte, S.D.
DOI: 10.1007/s12630-022-02352-8
2023

Efficacy of a hybrid technique of simultaneous videolaryngoscopy with flexible bronchoscopy in children with difficult direct laryngoscopy in the Pediatric Difficult Intubation Registry
Anaesthesia
Stein, M.L. and Park, R.S. and Kiss, E.E. and Adams, H.D. and Burjek, N.E. and Peyton, J. and Szmuk, P. and Staffa, S.J. and Fiadjoe, J.E. and Kovatsis, P.G. and Olomu, P.N. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Garcia-Marcinkiewicz, A.G. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Guris, R.J.D. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Goldfarb, T. and Lingappan, A. and Egbuta, C. and Flynn, S. and Sarmiento, L. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Matuszczak, M. and Hunyady, A. and Holmes, C. and Sabato, S. and Matava, C. and Dalesio, N. and Greenberg, R. and Lucero, A. and Reynolds, P. and Lewis, I. and Haydar, B. and Schrock, C. and Nykiel-Bailey, S. and Marsh, J. and Peterson, M.B. and Lee, A.C.J. and Bhattacharya, S. and Jagannathan, N. and Lardner, D. and Crockett, C. and Robertson, S. and Sathyamoorthy, M. and Chiao, F. and Patel, J. and Sharma, A. and Templeton, T.W. and Marin, P.E. and P{\'e}rez-Pradilla, C. and Singh, N. and Taicher, B. and von Ungern-Sternberg, B.S. and Sommerfield, D. and Hauser, N. and Hesselink, E. and Lewkowitz-Shpuntoff, H. and Castro, P. and Perez, N.R.R. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Rubin, K. and Meserve, J. and Lord, C. and Lee, A. and Heitmiller, E. and Valairucha, S. and Dalal, P. and Tran, T. and Lee, L.K. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S.
DOI: 10.1111/anae.16049
2023

Difficult or impossible facemask ventilation in children with difficult tracheal intubation: a retrospective analysis of the PeDI registry
British Journal of Anaesthesia
Garcia-Marcinkiewicz, A.G. and Lee, L.K. and Haydar, B. and Fiadjoe, J.E. and Matava, C.T. and Kovatsis, P.G. and Peyton, J. and Stein, M.L. and Park, R. and Taicher, B.M. and Templeton, T.W. and Bruins, B.B. and Stricker, P. and Laverriere, E.K. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Daly Guris, R.J. and Sequera-Ramos, L. and Teen, M.S. and Oke, A. and Hsu, G. and Lingappan, A. and Egbuta, C. and Flynn, S. and Sarmiento, L. and Goldfarb, T. and Kiss, E.E. and Olomu, P.N. and Szmuk, P. and Mireles, S. and Murray, A. and Whyte, S. and Jain, R. and Matuszczak, M. and Hunyady, A. and Bosenberg, A. and Tham, S. and Low, D. and Holmes, C. and Sabato, S. and Dalesio, N. and Greenberg, R. and Lucero, A. and Reynolds, P. and Lewis, I. and Schrock, C. and Nykiel-Bailey, S. and Starker, E. and Szolnoki, J. and Brooks-Peterson, M. and Bhattacharya, S. and Burjek, N.E. and Jagannathan, N. and Lardner, D. and Watkins, S. and Crockett, C. and Moore, J. and Robertson, S. and Sathyamoorthy, M. and Chiao, F. and Patel, J. and Sharma, A. and Echeverry Marin, P. and P{\'e}rez-Pradilla, C. and Singh, N. and von Ungern-Sternberg, B.S. and Sommerfield, D. and Bilen-Rosas, G. and Lewkowitz-Shpuntoff, H. and Castro, P. and Riveros Perez, N.R. and de Graaff, J.C. and Vega, E. and Gonz{\'a}lez, A. and Ostermann, P. and Rubin, K. and Lord, C.T. and Lee, A. and Heitmiller, E. and Valairucha, S. and Dalal, P. and Tran, T. and Ayad, I. and Rehman, M. and Fernandez, A. and Zamora, L. and Ravula, N. and Shaik, S.
DOI: 10.1016/j.bja.2023.02.035
2023

Blood pressure nomograms for children undergoing general anesthesia, stratified by age and anesthetic type, using data from a retrospective cohort at a tertiary pediatric center
Journal of Clinical Monitoring and Computing
Rosa J. Hillgruber and Pavel Lutskov and Nicholas C. West and Simon Whyte and Matthias Görges
DOI: 10.1007/s10877-022-00811-7
12/2022

Identification of Requirements for a Postoperative Pediatric Pain Risk Communication Tool: Focus Group Study With Clinicians and Family Members
JMIR Pediatrics and Parenting
Michael D Wood and Kim Correa and Peijia Ding and Rama Sreepada and Kent C Loftsgard and Isabel Jordan and Nicholas C West and Simon D Whyte and Elodie Portales-Casamar and Matthias Görges
DOI: 10.2196/37353
07/2022

A pharmacogenomic investigation of the cardiac safety profile of ondansetron in children and pregnant women.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Drögemöller BI and Wright GEB and Trueman J and Shaw K and Staub M and Chaudhry S and Miao F and Higginson M and Groeneweg GSS and Brown J and Magee LA and Whyte SD and West N and Carleton BC
DOI: 10.1016/j.biopha.2022.112684
PubMed: 35149390
02/2022

Identification of Requirements for a Postoperative Pediatric Pain Risk Communication Tool: Focus Group Study With Clinicians and Family Members (Preprint)
Michael D Wood and Kim Correa and Peijia Ding and Rama Sreepada and Kent C Loftsgard and Isabel Jordan and Nicholas C West and Simon D Whyte and Elodie Portales-Casamar and Matthias Görges
DOI: 10.2196/preprints.37353
02/2022

Sedation versus General Anesthesia for Tracheal Intubation in Children with Difficult Airways: A Cohort Study from the Pediatric Difficult Intubation Registry
Anesthesiology
Sequera-Ramos, L. and Laverriere, E.K. and Garcia-Marcinkiewicz, A.G. and Zhang, B. and Kovatsis, P.G. and Fiadjoe, J.E. and Lardner, D. and Von Ungern-Sternberg, B.S. and Sommerfield, D. and Holmes, C. and Sabato, S. and Ravula, N. and Jette, C. and Mireles, S. and Matava, C. and Whyte, S. and Vega, E. and Yang, L. and Echeverry-Marin, P. and P{\'e}rez-Pradilla, C. and Jagannathan, N. and Burjek, N.E. and Polaner, D. and Starker, E. and Szolnoki, J. and Brooks-Peterson, M. and Lee, A. and Heitmiller, E. and Rehman, M. and Fernandez, A. and Meserve, J. and Lord, C. and McCloskey, J. and Dalesio, N. and Koka, R. and Greenberg, R. and Park, R. and Peyton, J. and Stein, M.L. and Egbuta, C. and Flynn, S. and Bhattacharya, S. and Reynolds, P. and Lewis, I. and Haydar, B. and Sarmiento, L. and Richtsfeld, M. and Belani, K. and Robertson, S. and Sathyamoorthy, M. and Schrock, C. and De Graaff, J.C. and Soneru, C. and Singh, N. and Chiao, F. and Taicher, B. and Templeton, T. and Castro, P. and Perez, N.R.R. and Raman, V.T. and Beltran, R. and Bhalla, T. and Bruins, B.B. and Stricker, P. and Lockman, J.L. and Struyk, B. and Ward, C. and Nishisaki, A. and Kodavatiganti, R. and Guris, R.J.D. and Teen, M.S. and Mar{\'i}n, P.C.E. and Watkins, S. and Crockett, C. and Moore, J. and Goldfarb, T. and Olomu, P. and Szmuk, P. and Hopkins, P. and Glover, C. and Nguyen, K. and Shaw, T.L. and Olutoye, O. and Jain, R. and Matuszczak, M. and Hunyady, A. and Bosenberg, A. and Tham, S. and Low, D. and Bilen-Rosas, G. and Fehr, J. and Lee, L.K. and Ayad, I. and Patel, R. and Gooden, C.
DOI: 10.1097/ALN.0000000000004353
2022

Safety of antifibrinolytics in 6583 pediatric patients having craniosynostosis surgery: A decade of data reported from the multicenter Pediatric Craniofacial Collaborative Group
Paediatric Anaesthesia
King, M.R. and Staffa, S.J. and Stricker, P.A. and P{\'e}rez-Pradilla, C. and Nelson, O. and Benzon, H.A. and Goobie, S.M. and Abruzzese, C. and Asmal, I. and Bailey, K. and Barker, N. and Bhandari, A. and Beethe, A. and Binstock, W. and van den Bosch, C. and Bradford, V. and Bradley, J. and Bryan, K. and Brzenski, A. and Budac, S. and Busso, V. and de Castro, A. and Castro-Frenzel, K. and Chhabada, S. and Chiao, F. and Ching, J. and Cladis, F. and Claypool, D. and Collins, M. and Correll, L. and Costandi, A. and Dabek, R. and Dalesio, N. and Downard, M. and Echeverry, P. and Edala, T. and Edwards, C. and Ellison, P.R. and Enicker, B. and Falcon, R. and Fernandez, A. and Fernandez, P. and Fiadjoe, J. and Franzen, M. and Gangadharan, M. and Glover, C. and Gosman, A. and Governale, L. and Grivoyannis, A. and Grap, S. and Gries, H. and Griffin, A. and Hajduk, J. and Haas, T. and Hansen, J. and Hetmaniuk, M. and Homi, H.M. and Hsieh, H. and Hsieh, V. and Huang, H. and Ingelmo, P. and Ivanova, I. and Jain, R. and Kamel, G. and Kanmanthreddy, S. and Kars, M. and Koller, J. and Kowalczyk-Derderian, C. and Kugler, J. and Labovsky, K. and Lakheeram, I. and Lazar, A. and Lee, A. and Lee, J. and Madaree, A. and Malviya, S. and Martinez, J.L. and Mason, A. and Medellin, E. and Mehta, V. and Meier, P.M. and Levy, H.M. and Mueller, M. and Muhly, W.T. and Muldowney, B. and Nause-Osthoff, R. and Nelson, J. and Nicholson, J. and Nguyen, K.-P. and Nguyen, T. and Owens-Stubblefield, M. and Pankratz, M. and Parekh, U.R. and Parikh, M. and Patel, J. and Patel, R. and Patel, V. and Petersen, T. and Post, J. and Poteet-Schwartz, K. and Puglia, M.P. and Reddy, S.K. and Reid, R. and Ricketts, K. and McCormick, M.R. and Ryan, L. and Sbrollini, K. and Seidman, P. and Seubert, C. and Salik, I. and Singh, D.J. and Singhal, N.R. and Skitt, R. and Soneru, C. and Sorial, E. and Starker, E. and Stubbeman, B. and Sunder, R. and Sung, W. and Syed, T. and Szmuk, P. and Taicher, B.M. and Taylor, J. and Taylor, K. and Thompson, D. and Titler, S.S. and Ungar-Kastner, G. and Whyte, S. and Wong, A. and Wong, K. and Yates, H. and Zamora, L.
DOI: 10.1111/pan.14540
2022

Association of dexmedetomidine with recovery room and hospital discharge times: A retrospective cohort analysis
Pediatric Anesthesia
Nicholas West and Matthias Görges and Andrew Poznikoff and Simon Whyte and Stephan Malherbe
DOI: 10.1111/pan.14257
11/2021

The Effect of Carbetocin Dose on Transmural Dispersion of Myocardial Repolarization in Healthy Parturients Scheduled for Elective Cesarean Delivery Under Spinal Anesthesia: A Prospective, Randomized Clinical Trial
Anesthesia and Analgesia
Clunies-Ross, N. and Roston, T.M. and Taylor, J. and Whyte, S. and Albert, A. and Görges, M. and Chau, A.
DOI: 10.1213/ANE.0000000000004712
2021

A survey of the global impact of COVID-19 on the practice of pediatric anesthesia: A study from the pediatric anesthesia COVID-19 Collaborative Group
Paediatric Anaesthesia
Soneru, C.N. and Fernandez, A.M. and Bradford, V. and Staffa, S.J. and Raman, V.T. and Cravero, J. and Zurakowski, D. and Meier, P.M. and Balakrishnan, S. and Bansal, V. and Torres, A.B. and Beethe, A. and Benzon, H.A. and Bhandari, A. and Bocanegra, A. and Bould, D. and Peterson, M.B. and Brzenski, A. and Busso, V. and Cain, J.G. and Cassidy, M. and Cheon, E.C. and Chhabada, S. and Correll, L.R. and Dalesio, N.M. and Davidson, A. and Derderian, C. and Dhumak, V. and Disma, N. and D'Mello, A. and Echeverry, P. and Ellison, P.R. and Erb, T. and Fajardo, A. and Falcon, R.J. and Frugoni, B. and García, J. and Giraldo, O.L. and Glover, C.D. and Goeller, J. and Goobie, S.M. and Gooch, I. and Granados, L.M. and Grivoyannis, A. and Guruswamy, V. and Hesselink, E. and Hobbs, J. and Hunyady, A. and Jain, R. and Jorge-Reynolds, L. and Kato, M.A. and King, M.R. and Kitzman, J. and Koh, J. and Lester, A. and Lorinc, A. and Lozano, C. and Manupipatpong, K. and Matava, C. and McLuckie, D. and Merchant, K. and Levy, H.M. and Muldowney, B.L. and Navarro, J.A. and Nelson, J. and Patel, A. and Patel, R. and Ravula, N. and Reddy, D. and Reddy, S.K. and McCormick, M.R. and Roque, R. and Rosen, D. and Beel, E.R. and Rothschild, L. and Sarmiento, L. and Shadrina, A. and Shaw, R. and Sheth, M. and Simpao, A.F. and Singh, N. and Smith, T.E. and Soria, C. and Szmuk, P. and Taicher, B.M. and Tan, G.M. and Teng, H. and Edala, T. and Tighe, N. and Tom, S. and Trujillo, A. and Vishneski, S.R. and Vivas, J.P. and Samek, A.V. and von Ungern-Sternberg, B.S. and Whyte, S. and Wilder, R.T.
DOI: 10.1111/pan.14174
2021

A comparison of videolaryngoscopy using standard blades or non-standard blades in children in the Paediatric Difficult Intubation Registry
British Journal of Anaesthesia
Peyton, J. and Park, R. and Staffa, S.J. and Sabato, S. and Templeton, T.W. and Stein, M.L. and Garcia-Marcinkiewicz, A.G. and Kiss, E. and Fiadjoe, J.E. and von Ungern-Sternberg, B. and Chiao, F. and Olomu, P. and Zurakowski, D. and Kovatsis, P.G. and Sommerfield, D. and Holmes, C. and Ravula, N. and Jette, C. and Mireles, S. and Matava, C. and Whyte, S. and Vega, E. and Yang, L. and Echeverry-Marin, P. and Perez-Pradilla, C. and Starker, E. and Zieg, J. and Szolnoki, J. and Lee, A. and Heitmiller, E. and Rehman, M. and Zamora, L. and Fernandez, A. and Meserve, J. and Bhattacharya, S. and Reynolds, P. and Lewis, I. and Haydar, B. and Therrian, M. and Sarmiento, L. and Richtsfeld, M. and Belani, K. and Robertson, S. and Sathyamoorthy, K. and Schrock, C. and de Graaff, J. and Soneru, C. and Singh, N. and Taicher, B. and Castro, P. and Riveros Perez, N.R. and Stricker, P. and Lockman, J.L. and Galvez, J. and Isserman, R. and Struyk, B. and Ward, C. and Hsu, G. and Nishisaki, A. and Kodavatiganti, R. and Ramos, L.S. and Scheu, E. and Bruins, B. and Goldfarb, T. and Szmuk, P. and Jain, R. and Matuszczak, M. and Polaner, D. and Hunyady, A. and Bosenberg, A. and Tham, S. and Low, D. and Rosas, G.B. and Lee, L.K. and Iyah, I. and Dalesio, N. and Greenberg, R.
DOI: 10.1016/j.bja.2020.08.010
2021

A systematic review of outcomes reported in pediatric perioperative research: A report from the Pediatric Perioperative Outcomes Group
Paediatric Anaesthesia
Muhly, W.T. and Taylor, E. and Razavi, C. and Walker, S.M. and Yang, L. and de Graaff, J.C. and Vutskits, L. and Davidson, A. and Zuo, Y. and Pérez-Pradilla, C. and Echeverry, P. and Torborg, A.M. and Xu, T. and Rawlinson, E. and Subramanyam, R. and Whyte, S. and Seal, R. and Meyer, H.M. and Yaddanapudi, S. and Goobie, S.M. and Cravero, J.P. and Keaney, A. and Graham, M.R. and Ramos, T. and Stricker, P.A. and Malic, C.C. and von Ungern-Sternberg, B.S. and Shivera, T. and Yu, G.
DOI: 10.1111/pan.13981
2020

Effects of Dexmedetomidine on Blood Glucose and Serum Potassium Levels in Children Undergoing General Anesthesia: A Secondary Analysis of Safety Endpoints During a Randomized Controlled Trial.
Anesthesia and analgesia
Görges M and Poznikoff AK and West NC and Brodie SM and Brant RF and Whyte SD
DOI: 10.1213/ane.0000000000004154
PubMed: 31008751
04/2019

Effects of Dexmedetomidine on Myocardial Repolarization in Children Undergoing General Anesthesia: A Randomized Controlled Trial.
Anesthesia and analgesia
Görges M and Sherwin ED and Poznikoff AK and West NC and Brodie SM and Whyte SD
DOI: 10.1213/ane.0000000000004135
PubMed: 30985379
04/2019

Changes in QTc associated with a rapid bolus dose of dexmedetomidine in patients receiving TIVA: a retrospective study.
Görges M and Whyte SD and Sanatani S and Dawes J and Montgomery CJ and Ansermino JM
DOI: 10.1111/pan.12780
PubMed: 26507917
12/2015

Paediatrics
Surgeon's Guide to Anaesthesia and Perioperative Care
2014

The safety of modern anesthesia for children with long QT syndrome
Anesthesia and Analgesia
Whyte, S.D. and Nathan, A. and Myers, D. and Watkins, S.C. and Kannankeril, P.J. and Etheridge, S.P. and Andrade, J. and Collins, K.K. and Law, I.H. and Hayes, J. and Sanatani, S.
DOI: 10.1213/ANE.0000000000000389
2014

Paediatric cases
A Surgeon's Guide to Anaesthesia and Peri-Operative Care
Whyte, S. and Butterworth, S.
DOI: 10.1017/CBO9781139628808.016
2014

A retrospective audit to examine the effectiveness of preoperative warming on hypothermia in spine deformity surgery patients.
Görges M and Ansermino JM and Whyte SD
DOI: 10.1111/pan.12204
PubMed: 23738627
11/2013

Usability and performance characteristics of the pediatric air-Q® intubating laryngeal airway.
Whyte SD and Cooke E and Malherbe S
DOI: 10.1007/s12630-013-9918-6
PubMed: 23519724
06/2013

Normal Tp-e values in children.
Sanatani S and Whyte S
DOI: 10.1213/ane.0b013e31823554ac
PubMed: 22184612
01/2012

Normal Tp-e values in children
Anesthesia and Analgesia
Sanatani, S. and Whyte, S.
DOI: 10.1213/ANE.0b013e31823554ac
2012

Anaesthesia for elective ear, nose and throat surgery in children
Anaesthesia and Intensive Care Medicine
Brown, Z. and Whyte, S.
DOI: 10.1016/j.mpaic.2012.02.010
2012

Dexmedetomidine for co-analgesia in chemotherapy-induced severe enterocolitis.
Winton P and Whyte E and Reimer EJ and Davis J and Whyte S
DOI: 10.1111/j.1460-9592.2011.03575.x
PubMed: 21793978
09/2011

The effects of droperidol and ondansetron on dispersion of myocardial repolarization in children
Pediatric Anesthesia
DISHA MEHTA and SHUBHAYAN SANATANI and SIMON D. WHYTE
DOI: 10.1111/j.1460-9592.2010.03408.x
09/2010

Total intravenous anesthesia and spontaneous respiration for airway endoscopy in children--a prospective evaluation.
Malherbe S and Whyte S and Singh P and Amari E and King A and Ansermino JM
DOI: 10.1111/j.1460-9592.2010.03290.x
PubMed: 20337953
05/2010

Intubation via the intubating laryngeal airway in two pediatric patients with predicted difficult airways.
Peiris K and Traynor M and Whyte S
DOI: 10.1111/j.1460-9592.2009.03222.x
PubMed: 20078820
02/2010

Anaesthesia for elective ear, nose and throat surgery in children
Anaesthesia & Intensive Care Medicine
Permendra Singh and Simon Whyte
DOI: 10.1016/j.mpaic.2009.02.002
04/2009

Perioperative fluid and electrolyte balance in children
Anaesthesia & Intensive Care Medicine
Simon D. Whyte
DOI: 10.1016/j.mpaic.2008.10.006
02/2009

The effect of propofol concentration on dispersion of myocardial repolarization in children.
Hume-Smith HV and Sanatani S and Lim J and Chau A and Whyte SD
DOI: 10.1213/ane.0b013e3181815ce3
PubMed: 18713888
09/2008

Editorial
Current Anaesthesia and Critical Care
Whyte, S.D.
DOI: 10.1016/j.cacc.2008.09.002
2008

A comparison of the effect on dispersion of repolarization of age-adjusted MAC values of sevoflurane in children.
Whyte SD and Sanatani S and Lim J and Booker PD
DOI: 10.1213/01.ane.0000252417.23986.6e
PubMed: 17242080
02/2007

Torsades de pointes with sevoflurane.
Whyte SD and Sanatani S and Booker PD
DOI: 10.1111/j.1460-9592.2006.01994.x
PubMed: 17040316
11/2006

Anesthetic considerations in the management of Wilms' tumor.
Whyte SD and Mark Ansermino J
DOI: 10.1111/j.1460-9592.2006.01866.x
PubMed: 16677259
05/2006

The effects of propofol and sevoflurane on the QT interval and transmural dispersion of repolarization in children.
Whyte SD and Booker PD and Buckley DG
DOI: 10.1213/01.ane.0000140781.18391.41
PubMed: 15616054
01/2005

Anaesthesia and transmural dispersion of repolarisation in children
Canadian Journal of Anesthesia
Whyte, S.D. and Booker, P.D. and Buckley, D.G.
DOI: 10.1007/BF03023094
2005

The effects of propofol and sevoflurane on the QT interval and transmural dispersion of repolarization in children
Anesthesia and Analgesia
Whyte, S.D. and Booker, P.D. and Buckley, D.G.
DOI: 10.1213/01.ANE.0000140781.18391.41
2005

Newborn life support and the anaesthetist
Current Anaesthesia & Critical Care
Simon Whyte
DOI: 10.1016/j.cacc.2004.08.005
10/2004

Bispectral index during isoflurane anesthesia in pediatric patients.
Whyte SD and Booker PD
DOI: 10.1213/01.ane.0000117223.84646.36
PubMed: 15155318
06/2004

Bispectral index during isoflurane anesthesia in pediatric patients
Anesthesia and Analgesia
Whyte, S.D. and Booker, P.D.
DOI: 10.1213/01.ANE.0000117223.84646.36
2004

Usefulness of the Minute Ventilation Test in Predicting Successful Extubation in Newborn Infants: A Randomized Controlled Trial
Journal of Perinatology
Lorna M Gillespie and Simon D White and Sunil K Sinha and Steven M Donn
DOI: 10.1038/sj.jp.7210886
04/2003

Long QT syndrome and anaesthesia.
Booker PD and Whyte SD and Ladusans EJ
DOI: 10.1093/bja/aeg061
PubMed: 12594150
03/2003

Monitoring the depth of anaesthesia
British Journal of Anaesthesia
2003

Monitoring depth of anaesthesia by EEG
Continuing Education in Anaesthesia, Critical Care and Pain
Whyte, S.D. and Booker, P.D.
DOI: 10.1093/bjacepd/mkg106
2003

Paediatric applications of concentration-orientated anaesthesia
Best Practice & Research Clinical Anaesthesiology
Peter Driscoll Booker and Simon David Whyte
DOI: 10.1053/bean.2000.0138
03/2001

Premedication before intubation in UK neonatal units.
Whyte S and Birrell G and Wyllie J
DOI: 10.1136/fn.82.1.f38
PubMed: 10634840
01/2000

Premedication before intubation in UK neonatal units
Archives of Disease in Childhood: Fetal and Neonatal Edition
Whyte, S. and Birrell, G. and Wyllie, J.
DOI: 10.1136/fn.82.1.F38
2000

Paediatric basic life support: a practical assessment.
Whyte SD and Wyllie JP
DOI: 10.1016/s0300-9572(99)00056-8
PubMed: 10488937
07/1999

Patient-controlled analgesia: epidural fentanyl and i.v. morphine compared after caesarean section.
Cooper DW and Saleh U and Taylor M and Whyte S and Ryall D and Kokri MS and Desira WR and Day H and McArthur E
DOI: 10.1093/bja/82.3.366
PubMed: 10434817
03/1999

Neonatal resuscitation--a practical assessment.
Whyte SD and Sinha AK and Wyllie JP
DOI: 10.1016/s0300-9572(98)00143-9
PubMed: 10321844
01/1999

Neonatal resuscitation - A practical assessment
Resuscitation
Whyte, S.D. and Sinha, A.K. and Wyllie, J.P.
DOI: 10.1016/S0300-9572(98)00143-9
1999

Paediatric basic life support: A practical assessment
Resuscitation
Whyte, S.D. and Wyllie, J.P.
DOI: 10.1016/S0300-9572(99)00056-8
1999

Inability to adhere to current european neonatal resuscitation guidelines
Pediatric Research
Whyte, S.D. and Sinha, A.J. and Wyllie, J.P.
DOI: 10.1203/00006450-199809000-00110
1998

Research

CANadian PAediatric National Difficult Airway Registry (CANPANDA)
The first stage of this work was to establish a local difficult intubation database in our operating rooms. This went live in July 2017. The next stage was to expand the database to allow other Canadian tertiary paediatric anaesthesia departments to contribute data. This went live in May 2021.

G2ED50
This study measures 4 pharmacodynamic endpoints for progressively increasing depth of anaesthesia during induction, in children undergoing total intravenous anaesthesia. The goal is to better define the safety margin between loss of consciousness and cessation of breathing, in children of different ages, sex and - novelly - genetic ancestry. We'll undertake pharmacogenomic analyses for single nucleotide polymorphisms in potential anaesthetic receptor targets, to investigate any correlation between pharmacodynamic and pharmacogenomic variability.

Grants

2019 CRSU. Genetic ancestral differences in pharmacodynamic safety endpoints with propofol anaesthesia in children

2019 BCCHRI E2i. Genetic ancestral differences in pharmacodynamic safety endpoints with propofol anaesthesia in children

2016-2017 Evidence to Innovation Seed Grant

“BCCH Pediatric Anesthesia Difficult Airway Database

A Quality Improvement Initiative to Improve Safety in Patients with Difficult Airways”

Honours & Awards

Child & Family Research Institute Innovations in Acute Care & Technology Trainee Clinical Investigator Seed Grant - Project

"The effect of preoperative warming on surgical complications in pediatric scoliosis repair," $5,000. 2013.

Child & Family Research Institute Pharmaceutical Outcomes and Policy Innovations - Project

"5-HT3 Antagonists and Cardiac Safety," $42,667. 2014/15.

Research Group Members

Krystal Cardinal
Simrin Dhillon, Research Assistant
Aanisah Golam, Research Assistant
Halle Golding, Research Assistant
Laveniya Kugathasan
Jessica Luo, Clinical Research Assistant
Lindy Moxham
Bianca Vizcaino, Clinical Research Coordinator
Nick West, Clinical Research Coordinator