• Brown, Zoe

    Titles

    Investigator, BC Children's Hospital
    Clinical Assistant Professor, Department of Anesthesiology Pharmacology & Therapeutics, University of British Columbia
    Staff Anesthesiologist, BC Children's Hospital

    Degrees / Designations
    MBChB(Hons), BSc, FRCA
    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    Phone
    604-875-2711
    Fax
    604-875-3221
    Lab Phone
    604-875-2000 x6999
    Assistant
    Denise Taylor
    Assistant Phone
    604-875-2711
    Mailing Address

    BC Children's Hospital
    Room 1L7
    4480 Oak Street
    Vancouver BC V6H 3V4

    Affiliate Websites
    Research Areas

    Changes in intraoperative management to improve outcomes after anesthesia in children.

    Summary

    I recently completed a research project looking at changes in cardiac output, how much blood the heart pumps around the body per minute, when teenagers are turned onto their front prior to operations to fix the curvature of their back. We found that the amount of blood is significantly reduced on turning on to their front.

    This is leading on to further studies as I would like to look at how changes in anesthesia, for example the amount of fluid that we give these teenagers can affect their cardiac output. I am hoping to collaborate with the orthopediac surgeons and nephrologists to examine the incidence of kidney damage after surgery which may be related to changes in cardiac output.

    Current Projects

    I have just become part of a collaboration between orthopedics, nephrology and anesthesia, looking initially at the incidence of acute kidney injury (AKI) post-operatively, and then at different alterations to anesthesia management that could help reduce the incidence of AKI in the orthopedic population. Potentially this will involve changes in fluid management, possibly being guided by a cardiac output monitor, and observing the effects of non-steroidal drugs.

    Selected Publications

    For the latest publications, please visit Dr. Brown's ORCID profile. 

    Manuscripts:

    • Investigation of changes in cardiac output and arterial blood pressure when positioning children prone for idiopathic scoliosis correction surgery. Brown Z, Görges M, Cooke E, Malherbe S and Ansermino M. Anaesthesia, 2013 68 (7): 742-746

    • A Comparison of the Anaesthetic Costs of Day Case Surgery: Propofol Total Intravenous Anaesthesia and Volatile Anaesthesia. Blandford C, Brown Z, Montgomery J and Stocker M. Journal of One Day Surgery, 2013 23 (1)

    • Anaesthesia for elective paediatric ENT surgery. Brown Z and Whyte S. Anaesthesia and Intensive Care Medicine, 2012 13 (5): 234-239

    • Comparison of musical and linear tone scales for pulse oximeter sonification (Abstract). Brown Z, Edworthy J and Sneyd R. European Journal of Anaesthesiology, 2011 28 (S): 40-41

    • How costly is TIVA? A comparison of volatile and total intravenous anaesthesia for short day case procedures (Abstract). Blandford C, Brown Z, Montgomery J and Stocker M. Journal of One Day Surgery, 2010 20(S): 7

    Abstracts:

    • Cardiac index changes in children placed prone for surgery. Görges M, Brown Z, Cooke E, Malherbe S and Ansermino M. Accepted for poster discussion at Canadian Anaesthesia Society, Quebec City, 2012

    • Anaesthetic management of a large carinal tracheosophageal fistula. Brown Z and Bailey K. Accepted for poster presentation at Canadian Anaesthesia Society, Quebec City, 2012

    • Comparison of Musical and Linear Scales for Pulse Oximetry Sonification. Brown Z, Edworthy J and Sneyd R. Poster discussion at European Society of Anaesthesiology, Amsterdam, 2011

    • Anesthetic management of a large carinal tracheosophageal fistula. Brown Z and Bailey K. ASA annual conference, Washington, October 2012 (Presented by K Bailey)

    • Pain Management and Perceptions on the Neonatal Intensive Care Unit. Brown Z, Firdous F and Courtman S. Association of Paediatric Anaesthetists, Torbay, 2011

    Grants
    Innovation in Acute Care and Technology Research Grant
    Honours & Awards

    2012   

    • Best presentation by a Fellow, University of British Columbia, Anaesthesia, Pharmacology and Therapeutics Research Day
    • Best presentation, Innovations in Acute Care and Technology Research Day

    2002

    • Medical Faculty Elective Bursary Scheme Award
    • British Nutrition Foundation Elective Award

    1999

    • Edgeworth Prize in Physiology, Bristol University
    • Short-listed for the Victor Neale Paediatric Prize, Bristol University
    Research Group Members
    Research Staff:
    • Aryannah Umedaly
    • Nicholas West
    • Erin Cooke
    • Sonia Brodie
    • Nasim Lowlaavar
    • Richa Anand
    • Dustin Dunsmuir
    • Christian Petersen
    • Peter Chen
    • Leah Robertson
    Post Doctoral Fellows:
    • Matthias Görges
    • Ainara Garde
    • Walter Karlen
    • Klaske van Heusden
    Graduate Students:
    • Sara Khosravi
    • Kousha Talebian
    • Parastoo Dehkordi
    • Neda Eskandari
    • Shabaz Askari
    • Zoya Bastany