• Loock, Christine


    Investigator, BC Children's Hospital

    Associate Professor, Department of Pediatrics, University of British Columbia 

    Medical Director, Cleft Palate Program and Social Pediatrics RICHER program

    Degrees / Designations


    Primary Area of Research
    Brain, Behaviour & Development
    Secondary Area(s) of Research
    Lab Phone
    Mary Jane Hornaas
    Assistant Phone
    (604) 453-8383
    Mailing Address

    3644 Slocan Street
    Vancouver, BC V5M 3E8

    Affiliate Websites
    Research Areas
    • Social Pediatrics
    • Health Inequities
    • Child-health medical-home: children/families, integration / patient care / community services
    • Fetal Alcohol Spectrum Disorders
    • Pediatric Sleep Disorders

    Our start in life has a profound impact on our health and longevity. Early life matters. Early interventions have been proven to improve the developmental and life trajectories for the most vulnerable of our children, including those who have experienced in utero and early life adversity. Relationships also matter in the lives of children and youth; resiliency develops through the interactive effects of nature and nurture, both biology and environment. Brokering trust through respectful engagement and community partnerships creates opportunities for sustained interventions and healthier transition into adult health services.   

    Our research focuses on addressing disparities in health care engagement and inequities in health outcomes, with an effort to include populations of Canadian infants, children and youth who may be excluded, stereotyped, and/or become less visible in clinical research studies, due to socio-cultural barriers, material disenfranchisement and/or developmental diversity.

    Current Projects

    The RICHER (Responsive, Intersectoral, Child & Community Health, Education and Research) Program in Social Pediatrics is a translational research to practice community outreach program seeking to make health services (primary to specialized) accessible to socially vulnerable children and families. Our “place-based” work approach has brought provincial and national, and recently international, attention. We are in our 10th year of collaborative study with UBC, PHSA (Children’s, Women’s and Sunny Hill), and BC regional health authorities. The RICHER Social Pediatrics Initiative (SPI) is co-lead with Dr. Judith Lynam , Professor of Nursing (UBC, CFRI), and is a participatory research program with primary health providers  focusing  on improving methods to measure health care access, patient trust and engagement, and developmental outcomes for socially and materially disenfranchised children and youth. We recently have partnered with Public Health Ontario and other Canadian Social Pediatrics initiatives on a ‘Realist Synthesis of Social Pediatrics Theory’ literature review, with focus on mechanisms and outcomes for effective service provision and engagement with vulnerable child/youth populations.

    Our work with NeuroDevNet on Clinical Community Research with Fetal Alcohol Spectrum Disorders (FASD) is addressing gene-environment interactions, predictive biomarkers, and the relationship between structural alterations in the brain and functional outcomes. Thanks to our partnership with the communities engaged with the RICHER Social Pediatrics Initiative, we have been able to assist in the engagement and recruitment of families who often are unable to participate in research studies due to financial and other social barriers.  Many of our families have experienced early life adversity with adverse childhood experiences (ACES). We are committed to knowledge transfer and dissemination of new discoveries  from this national study of children with disabilities that will inform the development of effective interventions for children, youth and young adults affected by FASD and other disabilities, compounded by poverty, early life adversity and other ACES. This research is on-going, and in collaboration with Drs. Dan Goldowitz and and Tim Oberlander (BC Children's Hospital) and co-lead FASD Principle Investigators, Drs. James Reynolds and Joanne Weinberg,

    The Sleep/Wake Behaviour Clinic and Research Lab, Sunny Hill Health Centre for Children, has developed an innovative and internationally acclaimed approach to pediatric sleep research that uses mixed methods to measure, describe and address sleep problems in children and youth with disabilities, including those with both genetic and acquired craniofacial conditions, including Fetal Alcohol Spectrum Disorders (FASD). This collaborative research partnership is led by Dr. Osman Ipsiroglu (BC Children's Hospital), with our collaborations from the BC Children’s Provincial Cleft Palate Program with Dr. Douglas Courtemanche, Division of Plastic Surgery, C&W Chief of Staff, Dr. William McKellin, UBC Anthropology and Sociology, and Dr. Amy Salmon, researcher with the Canada FASD Research Network.

    Selected Publications


    • Cook, Jocelynn, Green, C., Lilley, C,   Anderson, S,  Baldwin, ME, Chudley, A, Conry, J, LeBlanc, N,  Loock, C,  Lutke, J, Mallon, B,  McFarlane, A,  Temple, V and  Rosales, T, for the Canada Fetal Alcohol Spectrum Disorder Research Network. "Fetal Alcohol Spectrum Disorder: a Guideline for Diagnosis Across the Lifespan",  CMAJ February 16, 2016 188:191-197; published ahead of print December 14, 2015, doi:10.1503/cmaj.141593 PMID: 26668194

    • Ipsiroglu OS , McKellin WH , Carey N , Loock C. (2013). "'They silently live in terror…' why sleep problems and night-time related quality-of-life are missed in children with a fetal alcohol spectrum disorder." Social science & medicine (1982). 79: 76-83. PMID: 23305724

    • Jan, J.E., Asante, K.O., Conry, J.L., Fast, D.K., Bax, M.C., Ipsiroglu, O.S., Bredberg, E., Loock, C.A., & Wasdell, M.B.(2010). "Sleep Health Issues for Children with FASD: Clinical Considerations". International journal of pediatrics. 2010: 2010. PMID: 20706655

    • LaFrance, M.A., McLachlan, K., Nash, K., Andrew, G., Loock, C., Oberlander, T., Koren, G., & Rasmussen, C. (2014). "Evaluation of the Neurobehavioral Screening Tool in Children With Fetal Alcohol Spectrum Disorder (FASD)". Journal of Population Therapeutics and Clinical Pharmacology, 21: e197-e:210. PMID: 24897061

    • McLachlan, Kaitlyn, Carmen Rasmussen, Tim Oberlander, Christine Loock, Jacqueline Pei, Gail Andrew, James Reynolds, Joanne Weinberg, "Dysregulation of the Cortisol Diurnal Rhythm following Prenatal Alcohol Exposure and Early Life Adversity", Alcoholism: Clinical and Experimental Research, (Accepted 2016) 

    Social Pediatrics:

    • Loock, C, Suleman, S, Lynam, J, Scott, L, &Tyler, I.  Linking In & Linking Across using a RICHER Model: Social Pediatrics and Inter–professional Practices at UBC. UBC Medical Journal, in press (March 2016).

    • Wong, S.T., Lynam, M.J., Khan, K., Scott, L. & Loock, C. (04 Oct 2012)  The social paediatrics initiative: a RICHER model of primary health care for at risk children and their families. BMC Pediatrics, 12:158 PMID: 23034058

    • Lynam, M.J., Scott, L., Loock, C.L., Wong, S. (2011). The RICHER Social Pediatrics Model: Fostering Access and Reducing Inequities in Children’s Health, Healthcare Quarterly. 14 Special Issue, (3): 41-56. PMID: 22008572  

    • Lynam, M.J., Loock, C., Scott, L., Wong, S., Munroe, V. & Palmer, B.(2010) Social Pediatrics: Creating organizational processes and practices to foster health care access for children ‘at risk’.  Journal of Research in Nursing.  OnlineFirst February 15: doi:10,1177/17449871093605/  pp: 1-17.

    • Lynam, M. J., Loock, C., Scott, L. & Khan, K.B. (2008) Culture, health and inequalities: new paradigms, new practice imperatives.  Journal of Research in Nursing , 13(2): 138-148. (Inaugural Publication from CIHR Study)


    To be updated with input from BB&D Theme lead, T. Oberlander.  Please refer to CVs of BC Children's Hospital Investigators: Oberlander, Ipsiroglu and Lynam for prior grants as co-applicant.

    Honours & Awards
    • Queen Elizabeth II Diamond Jubilee Medal for service to the community, Governor General of Canada, 2012, presented by Minister of Parliament, Dr. Hedy Fry, January 17, 2013

    • BC Pediatrics Society Judith Hall Advocacy Award, November 2015

    • Canadian Pediatric Society Certificate of Merit, 2009

    • Starfish Award  "Having the Courage to Make a Difference": international award for researchers and health, education and social service professionals in the field of  FASD, 1st recipient, UBC Continuing Interprofessional Education International FASD Conference, April 2008

    • Southern Methodist University Distinguished Alumni History Maker Award, 2014;  Silver Anniversary SAM Award, 2005; Distinguished Alumni, 1996, M Award 1976

    Research Group Members

    Research Team Co-Investigators:

    • Judith Lynman, PhD, Professor, UBC School of Nursing (Co-Investigator in Social Pediatrics)
    • Tim Oberlander, MD, Developmental Pediatrics (Neuro-Dev-Net: FASD)
    • Osman Ipsiroglu, MD, PhD, Developmental Pediatrics (Sleep and FASD; Sleep and Craniofacial)


    • Shazeen Suleman, MD, Pediatrics Resident, U of T
    • Matt Carwana, MD, Pediatrics Resident, UBC
    • Samara Laskin, MD, Pediatrics Resident, UBC
    • Ariel Singer, MD, Pediatrics Resident, U Ottawa