• Barker, Collin

    Investigator, BC Children's Hospital
    Clinical Associate Professor, Division of Gastroenterology, Department of Pediatrics, University of British Columbia
    Degrees / Designations
    M.Sc. (Epid), MD, FRCPC
    Primary Area of Research
    Childhood Diseases
    Secondary Area(s) of Research
    Lab Phone
    Deborah Finlay
    Assistant Phone
    604-875-2332 Ext. 1
    Mailing Address
    BC Children's Hospital
    Room K4-180
    4480 Oak Street
    Vancouver, BC V6H 3V4
    Affiliate Websites
    Research Areas

    •  Pediatric gastrointestinal complications
    •  Epidemiology of gastrointestinal diseases in pediatric patients


    My area of interest is pediatric gastrointestinal complications, including examining current medical practices within Pediatric Gastroenterology. My main research focuses on using clinical trials and databases to increase understanding, improving methods of patient care, and evaluating whether alternative options of establishing diagnoses or care would be as, or more, efficacious and cost-effective as the care currently being given. Under these directives, a database project on GI complications in oncology patients is being completed. As well, alternative approaches for investigating celiac disease in order to streamline the process of its detection and diagnosis for both the patient and medical system are being researched. Concurrently, we are developing a project to analyze the effects of low body mass index for patients undergoing bone marrow transplants in order to see if this adversely affects their clinical outcomes. Finally, in collaboration with Dr. Rick Schreiber, a nation-wide study designed to look at the experience of patients with biliary artesia throughout Canada is being created.

    Current Projects

    The assessment of pediatric oncology patients for gastrointestinal complications and how to minimize these complications in this patient population by using databases to identify risk factors for adverse outcomes and recommendations to minimize these risk factors for future patients. Looking specifically at low body mass index and outcomes post stem cell transplantation. Assessment of the prevalence of lactose intolerance post stem cell transplantation and associated complications.

    Examination of current medical practices within the pediatric gastroenterology division and using linked databases and prospective clinical trials to evaluate whether alternative options of establishing diagnoses or care would be as or more efficacious and cost-effective as the care is currently being given. Looking specifically at celiac disease and the screening TTG antibody test.

    Selected Publications

    Babu TGL, Jacobson K, Riley MR, Phang M, Barker CC. Endoscopic hemostasis in a neonate with a bleeding duodenal ulcer. Submitted to Journal of Pediatric Gastroenterology and Nutrition.

    Barker CC, Anderson RA, Sauve R, Butzner JD. GI complications in pediatric patients post-BMT. Submitted to Bone Marrow Transplantation.

    Barker CC, Mitton C, Jevon G, Mock T. Can TTG replace small bowel biopsy to diagnose celiac disease in select pediatric patients? Pediatrics, 2005;115(5).

    Barker CC, Butzner JD, Brant R, Anderson RA, Sauve. Incidence, risk factors and mortality of veno-occlusive disease in pediatric hematopoietic stem cell transplant recipients. Bone Marrow Transplantation, 2003;32:79-87.

    Leung AKC, Lemay J-F and Barker CC. Recurrent abdominal pain in children. Canadian Journal of Diagnosis, 2002;5:68-78.

    Al Otaibi A, Barker CC, Anderson R, Sigalet DL. Neutropenic enterocolitis (typhilitis) after pediatric bone marrow transplant. Journal of Pediatric Surgery, 2002;37:770-772.

    Barker CC, Butzner JD, Woodman RC, Parsons HG. Crohn’s-like enteritis presenting as hypoglycemia in a patient with Glycogen Storage Disease type 1b, treated with G-CSF and splenectomy. Journal of Pediatric Gastroenterology and Nutrition, 2001;32:197-200.

    Honours & Awards
    Research Group Members