• Chipperfield, Kate

    Investigator, BC Children's Hospital

    Head, Division of Hematopathology, BC Children's Hospital 
    Clinical Associate Professor, Department of Pathology and Laboratory Medicine, University of British Columbia

    Degrees / Designations


    Primary Area of Research
    Childhood Diseases
    Secondary Area(s) of Research
    Lab Phone
    Michelle Dittrick
    Assistant Phone
    604-875-2345 ext. 4679
    Mailing Address

    BC Children's Hospital
    4480 Oak Street
    Room 2K49
    Vancouver, BC  V6H 3V4

    Affiliate Websites
    Research Areas
    • Transfusion medicine 
    • Hematopathology

    Red blood cell (RBC) transfusion is a mainstay of treatment for individuals requiring surgery, with traumatic injury, undergoing chemotherapy and with anemia due to bone marrow failure or other medical conditions. Despite this, red cell transfusion has been associated with poorer outcome in many of these patient populations [Hebert, 1999, Villaneuva 2013]. As well, it is a costly treatment and the product is often in short supply due to demands in excess of donor availability. Utilization trends increase year over year on a provincial and national basis, and this is unlikely to change in light of our aging population.

    For these reasons, there is interest at all levels of care to ensure that RBC transfusion is undertaken only when necessary; when no other reasonable treatment option is available. My current research focuses on assessing blood transfusion practices and adherence to current recommendations. 

    Current Projects

    I am currently supervising a project to audit RBC transfusions administered across various hospitals in Greater Vancouver. We will gauge whether the transfusion was appropriate or inappropriate based on most current guidelines. The cumulative results of the audit will provide information to hospital Transfusion Medicine (TM) leaders, ordering clinicians, hospital executive and the Ministry of Health (MoH), and form a baseline for future RBC Utilization Management (UM) endeavors. This information will have the potential to influence quality outcomes for patients.

    Selected Publications

    Ponnampalam A, Growe G, Loftus P, Chipperfield K, Bigham M. Acquired peanut hypersensitivity following platelet transfusion. Transfus Med. 2014 Dec;24(6):426-7. doi: 10.1111/tme.12148. Epub 2014 Sep 2.

    Heidary B, Bell N, Ngai J, Simons R, Chipperfield K, and Hameed SM. Temporal trends in the treatment of severe Traumatic Hemorrhage. Am J of Surgery. 2012 (203), 568-573.

    Trudeau J, Waters T, and Chipperfield K. Should intraoperative cell-salvaged blood be used in patients with suspected or known malignancy? Can J Anesthesia. Epub 21 Sept 2012.


    2010-2014. Co DIVO RCT: A randomized controlled trial of high quality platelet concentrates as determined by ThromboLUX score versus standard of care platelets in patients with hematological malignancy.

    2011. VCH Quality and Patient Safety. Development of On-line tutorial - Appropriate TM Practice for MD’s.

    2010-2011. Canadian Blood Services Grant. (Co-PI with E. Maurer) Comparison of in vivo outcome following transfusion of dynamic light scattering screened versus unscreened platelets.

    Honours & Awards

    Award for Excellence in Clinical Service, UBC Dept of Pathology and Laboratory Medicine, 2011.

    Faculty of Medicine Clinical Excellence in Teaching Award, UBC. May 2007.

    Education Award for Excellence, UBC Dept of Pathology & Laboratory Medicine, May 2007.

    Master Teacher Award (Hematology/Transfusion Medicine), Awarded by UBC Anesthesia Residents. 2006.

    St. Thomas More Undergraduate Scholarship, 1991.

    Province of Saskatchewan General Proficiency Award, 1990.

    Research Group Members