• Holsti, Liisa


    Investigator, BC Children's Hospital
    Associate Professor, Department of Pediatrics, University of British Columbia
    Tier 2 Canada Research Chair in Neonatal Health and Development

    Degrees / Designations
    BSR, MA, PhD
    Primary Area of Research
    Healthy Starts
    Secondary Area(s) of Research
    (604) 875-2000 ext. 5200
    (604) 875-3212
    Lab Phone
    Sasha Pavlovich
    Assistant Phone
    (604) 875-2000 ext 6992
    Mailing Address

    BC Children's Hospital Research Institute
    Clinical Support Building
    V3-327, 950 West 28th Avenue
    Vancouver, BC, V5Z 4H4

    Research Areas
    • Developmental Care Program
    • Assessing and treating stress and pain responses in preterm infants in the neonatal intensive care nursery

    The Developmental Care Program centers on finding ways to accurately assess and effectively treat stress and pain responses in preterm infants in the Neonatal Intensive Care Unit. We are conducting a comprehensive program of research that includes studies which are descriptive, mechanistic and interventionist; outcome measures ranging from cellular to behavioural levels; and mothers, fathers and infants born from the earliest gestational ages to term.

    Current Projects


    Selected Publications

    Valerie BO, Holsti L, Linhares MBM. Neonatal pain and developmental outcomes in  children born preterm: A systematic review. Clin J Pain. 2015;31:355–362. PMID: 24866853

    Glegg SMN, Holsti L, Stanton S, Hanna S, Velikonja D, Ansley B, Sartor D, Brum C.‎ Using virtual reality in clinical practice: A multi-site exploratory study. NeuroRehabilitation. 2014;35:563-577. PMID: 25238866

    Tatla SK, Jarus T, Virji-Babul N, Holsti L. The development of the Pediatric Motivation Scale for rehabilitation: A pilot study. Canadian Journal of Occupational Therapy. 2014;1-3: DOI: 10.1177/0008417414556884. PMID: 26281433

    Mahon P, Holsti L, Albersheim, SA.  Development of the Fathers’ Support Scale: Neonatal  Intensive Care Unit (FSS:NICU): Development and initial content validation. J Neonat Nurs. 2015;21:63-71.

    Mahon P, Holsti L, Siden H, Strahlendorf C, Turnham L, Giaschi D.  Using colours to   assess pain in toddlers: Validation of ‘The Rainbow Pain Scale’: A proof of principle study. Journal of Pediatric Oncology Nursing. 2014 Available on line DOI: 10.1177/1043454214555197. PMID: 25416519

    Lam MY, Tatla SK, Lohse KR, Hoens A, Miller K, Holsti L, Virji-Babul N, Van der Loos HFM.  Perceptions of technology and its use for therapeutic application for individuals with hemiparesis: Findings from adult and paediatric focus groups. Journal of Medical Internet Research: Rehabilitation and Assistive Technologies. (Open Access Journal). 2015;2(1):e1.

    Lavoie PM, Stritzke A, Ting J, Jabr M, Jain A, Kwan E, Chakkarapani E, Brooks McNamara PJ Brant R, Holsti L. Oral glucose to reduce stress during neonatal echocardiography: A randomized trial. Archives of Disease in Childhood-Fetal Neonatal Ed. Research Letter. In press May, 2015

    Schiavenato M, Holsti L.Defining Procedural Distress in the NICU and What Can Be Done About It. Neonatal Netw. 2017 Jan 1 PMID:28137348 


    Honours & Awards

    Tier 2 Canada Research Chair in Neonatal Health and Development - 2010-2020

    Canadian Child Health Clinician Scientist Program Career Award - 2005-2009 

    BCRICWH Postdoctoral Fellowship - 2004-2005 

    CIHR/COTF Post Doctoral Fellowship - 2001-2004

    Research Group Members
    • Sasha Pavlovich, MA – Research Assistant
    • Stephanie Glegg – PhD Student
    • Leisha Vandermey, BScN – Research Nurse