• Enarson, Paul


    Investigator, BC Children's Hospital
    Emergency Physician, Education Lead, Division of Pediatric Emergency Medicine, BC Children's Hospital
    Clinical Assistant Professor, Department of Pediatrics, Faculty of Medicine, University of British Columbia

    Degrees / Designations
    MD, PhD, FRCPC
    Primary Area of Research
    Evidence to Innovation
    Secondary Area(s) of Research
    604-875-2345 ext. 7261
    Lab Phone
    Christina Tou
    Assistant Phone
    604-875-2345 ext. 7333
    Mailing Address

    Emergency Department, BC Children's Hospital
    Room 1K-88
    4480 Oak Street
    Vancouver, BC  V6H 3V4

    Affiliate Websites
    Research Areas
    • Sepsis
    • Pediatric Emergency Care
    • Sedation

    My research interests involve both sepsis and quality assurance in the emergency department. 

    Sepsis is a term used to describe what happens when the body mounts an inflammatory response to an infection. In fact, this response is what often does more damage to a patient, rather than the infection itself. My research interest with respect to sepsis is to try and determine early on which patient is going to have a minimal response and which patient is going to have a catastrophic response leading to shock.

    In addition, I have an interest in how we sedate patients in the emergency room when painful procedures are required. I currently am involved in implementing new, and hopefully better, medications for this and studying their implementation to ensure that they are safe and effective in for use in the emergency room.

    Current Projects

    My current research involves three projects. 

    The first is a national anaphylaxis registry (C-CARE). I am the site lead for UBC. The primary objective of the CCARE study (Cross Canada Anaphylaxis Registry) is to assess the rate, triggers and management of anaphylaxis in emergency medical services, emergency departments, and allergy clinics across Canada. It is hoped that through this registry, we will obtain the first reliable estimate of anaphylaxis rates in Canada using prospectively collected data from several sources. The registry will also identify conventional and emerging triggers for anaphylaxis and explore demographic and environmental factors that may be involved in its pathogenesis. By characterizing current diagnostic and treatment practices for anaphylaxis, the C-CARE initiative will identify related gaps and inform the development of more comprehensive and effective management strategies.

    The second project is a multi-disciplinary study, led by Dr. Ash Singhal at BC Children’s Hospital, looking at if we can obtain better views of younger patients’ (ages 1-5 years) optic discs with an indirect ophthalmoscope if we distract them with images on an iPad. Indirect ophthalmoscope exams are an important part of any neurologic exam, but also extremely difficult in younger, uncooperative patients. It is hoped that this new technique will make this exam much easier. My role is the study lead for the emergency department arm of the study.

    The third project relates to safe implementation of new sedation drugs for the emergency department. We currently are in the process of implementing two new drugs, nitrous oxide and propofol, and I have been working on reviewing the literature to ensure safety and efficacy of these two drugs. Once implemented, we will be working on quality assurance projects to ensure that these drugs are suitable for our emergency department at BC Children’s Hospital.

    Selected Publications

    Sabhaney V. and P. Enarson. Commentary on 'Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections'. Evidence-Based Child Health: A Cochrane Review Journal. In press.

    Weingarten L, P. Enarson, and T. Klassen. 2013. Encephalitis. Pediatric Emergency Care 29(2):235-241. PMID: 23546434

    Enarson, P., S. Gouin, and R. Goldman. 2011. Child Health: Dimenhydrinate Use for Children with Vomiting. Canadian Family Physician 57(4):431-432. PMID: 21490354

    Honours & Awards

    2012 UBC Department of Pediatrics Rookie of the Year Award
    2005 Leaders in Medicine Scholarship
    2004 Leaders in Medicine Scholarship
    2004 AHFMR Full Studentship Renewal
    2003 AHFMR MD/PhD Full Studentship
    2002 AHFMR Full Studentship Renewal
    2002 Journal of Cell Science Travel Fellowship
    2001 Faculty of Medicine Travel Scholarship
    2001 AHFMR Full Studentship Renewal
    2000 Alberta Heritage Foundation for Medical Research (AHFMR) Full Studentship
    2000 Faculty of Medicine Trust Award
    1999 Graduate Conference Travel Grant Award
    1991 Alexander Rutherford Scholarship

    Research Group Members