- Overview
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I am a developmental pediatrician studying how early social experience (prenatal maternal mental illness and psychotropic medication exposure) influences the developmental origins of stress and self-regulation and its impact on thinking, learning and behaviour during childhood.
- Publications
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Examining the interaction between prenatal stress and polygenic risk for attention-deficit/hyperactivity disorder on brain growth in childhood: Findings from the DREAM BIG consortium
Developmental Psychobiology
DOI: 10.1002/dev.22481
2024MyWeekInSight: Designing and Evaluating the Use of Visualization in Self-Management of Chronic Pain by Youth
arXiv
DOI: 10.48550/arXiv.2405.20508
2024A developmental framework for understanding the influence of sex and gender on health: Pediatric pain as an exemplar
Neuroscience and Biobehavioral Reviews
DOI: 10.1016/j.neubiorev.2024.105546
2024Removing barriers to accessing medical cannabis for paediatric patients
Paediatrics and Child Health (Canada)
DOI: 10.1093/pch/pxac129
2024Association of pre-existing maternal cardiovascular diseases with neurodevelopmental disorders in offspring: a cohort study in Sweden and British Columbia, Canada
International Journal of Epidemiology
DOI: 10.1093/ije/dyad184
2024A systematic review of self and observer assessment of pain and related functioning in youth with brain-based developmental disabilities
Pain
DOI: 10.1097/j.pain.0000000000003066
2024A multi-centre, tolerability study of a cannabidiol-enriched Cannabis Herbal Extract for chronic headaches in adolescents: The CAN-CHA protocol
PloS one
DOI: 10.1371/journal.pone.0290185
2024An examination of executive functioning in adolescents with FASD in a self-regulation intervention
Applied Neuropsychology: Child
DOI: 10.1080/21622965.2024.2349301
2024Can we more precisely classify exposure to antenatal depression and anxiety in multivariable prediction models of pregnancy and birth outcomes: a population-based cohort study
BMC Psychiatry
DOI: 10.1186/s12888-023-05284-9
2023The application of epiphenotyping approaches to DNA methylation array studies of the human placenta
Epigenetics and Chromatin
DOI: 10.1186/s13072-023-00507-5
2023The Role of Parenting Stress as a Mediator in the Relationship Between Postpartum Depressive Symptoms and Early Childhood Internalizing Behaviour
Child Psychiatry and Human Development
DOI: 10.1007/s10578-023-01596-9
2023Response: Maternal infection, prenatal antibiotics and risk of autism in the offspring
Paediatric and Perinatal Epidemiology
DOI: 10.1111/ppe.12996
2023Prenatal serotonin reuptake inhibitor antidepressant exposure, SLC6A4 genetic variations, and cortisol activity in 6-year-old children of depressed mothers: A cohort study
Developmental Psychobiology
DOI: 10.1002/dev.22425
2023Neurodevelopmental pediatrics: Genetic and environmental influences
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
DOI: 10.1007/978-3-031-20792-1
2023Conditioning induced placebo-like and nocebo-like effects of thermal discomfort in adults but not in youth
British Journal of Pain
Weik, E. and Neuenschwander, R. and Edgington, B. and Jensen, K. and Tipper, C.M. and Oberlander, T.F.
DOI: 10.1177/20494637231153364
2023Associations between maternal depressive symptoms and selective serotonin reuptake inhibitor antidepressant treatment on internalising and anxiety behaviours in children: 12-year longitudinal study
BJPsych Open
Hutchison, S.M. and Brain, U. and Grunau, R.E. and Kuzeljevic, B. and Irvine, M. and M{\^a}sse, L.C. and Oberlander, T.F.
DOI: 10.1192/bjo.2022.623
2023Anxiety symptoms, psychological distress, and optimism in school staff: Testing associations with stressors and coping during the second year of the COVID-19 pandemic
Journal of Affective Disorders Reports
DOI: 10.1016/j.jadr.2023.100662
2023Placebo effects in children with autism spectrum disorder
Developmental Medicine and Child Neurology
DOI: 10.1111/dmcn.15574
2023Feasibility and acceptability of collecting umbilical cord tissue for prenatal cannabis research: A mixed-methods research study
Women's Health
DOI: 10.1177/17455057231219599
2023Family Perspectives on In-Home Multimodal Longitudinal Data Collection for Children Who Function Across the Developmental Spectrum
Journal of Developmental and Behavioral Pediatrics
DOI: 10.1097/DBP.0000000000001183
2023Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies
Frontiers in Pharmacology
DOI: 10.3389/fphar.2023.1094698
2023Exogenous oxytocin administration during labor and autism spectrum disorder
American Journal of Obstetrics and Gynecology MFM
DOI: 10.1016/j.ajogmf.2023.101010
2023Association between prenatal antibiotic exposure and autism spectrum disorder among term births: A population-based cohort study
Paediatric and Perinatal Epidemiology
DOI: 10.1111/ppe.12972
2023Gestational stress and perinatal SSRIs differentially impact the maternal and neonatal microbiome-gut-brain axis
Journal of Neuroendocrinology
DOI: 10.1111/jne.13261
2023“Making Data the Drug”: A Pragmatic Pilot Feasibility Randomized Crossover Trial of Data Visualization as an Intervention for Pediatric Chronic Pain
Children
DOI: 10.3390/children10081355
2023Rethinking diagnosis-based service models for childhood neurodevelopmental disabilities in Canada: a question of equity
Paediatrics and Child Health (Canada)
DOI: 10.1093/pch/pxac131
2023Preface
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
2023Pain and symptom management in neurodevelopmental disorders: Sensory and nociceptive function/pain and symptom management
Neurodevelopmental Pediatrics: Genetic and Environmental Influences
DOI: 10.1007/978-3-031-20792-1_43
2023Behavior regulation skills are associated with adaptive functioning in children and adolescents with prenatal alcohol exposure
Applied Neuropsychology: Child
Emily Gardiner and Sarah M. Hutchison and Kaitlyn McLachlan and Carmen Rasmussen and Jacqueline Pei and Louise C. Mâsse and Tim F. Oberlander and James N. Reynolds
DOI: 10.1080/21622965.2021.1936528
10/2022Placebo and nocebo effects in youth: subjective thermal discomfort can be modulated by a conditioning paradigm utilizing mental states of low and high self-efficacy
British Journal of Pain
Ella Weik and Regula Neuenschwander and Karin Jensen and Tim F Oberlander and Christine Tipper
DOI: 10.1177/20494637211020042
02/2022Medicinal cannabis in children and adolescents with autism spectrum disorder: A scoping review
Child: Care, Health and Development
Sarah Fletcher and Colleen Pawliuk and Angie Ip and Linda Huh and S. Rod Rassekh and Tim F. Oberlander and Harold Siden
DOI: 10.1111/cch.12909
01/2022Complex chronic conditions among children born to women with schizophrenia
Schizophrenia Research
Toufeili, A. and Cohen, E. and Ray, J.G. and Wilton, A.S. and Brown, H.K. and Saunders, N.R. and Dennis, C.L. and Holloway, A.C. and Morrison, K.M. and Hanley, G.E. and Oberlander, T.F. and Bérard, A. and Tu, K. and Barker, L.C. and Vigod, S.N.
DOI: 10.1016/j.schres.2021.12.018
2022Neighborhood environmental exposures and incidence of attention deficit/hyperactivity disorder: A population-based cohort study
Environment International
Yuchi, W. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Davis, Z. and Guhn, M. and Jarvis, I. and Jerrett, M. and Nesbitt, L. and Oberlander, T.F. and Sbihi, H. and Su, J. and van den Bosch, M.
DOI: 10.1016/j.envint.2022.107120
2022Developmental profiles of children at risk for autism spectrum disorder at school entry
Autism Research
Ip, A. and Poon, B.T. and Hanley, G. and Guhn, M. and Oberlander, T.F.
DOI: 10.1002/aur.2742
2022Autism Risk and Perinatal Antibiotic Use
Pediatrics
Nitschke, A.S. and Karim, J.L. and Vallance, B.A. and Bickford, C. and Ip, A. and Lanphear, N. and Lanphear, B. and Weikum, W. and Oberlander, T.F. and Hanley, G.E.
DOI: 10.1542/peds.2022-057346
2022The COVID-19 pandemic impacted maternal mental health differently depending on pregnancy status and trimester of gestation
Research Square
DOI: 10.21203/rs.3.rs-1167874/v1
2022The Canadian Mother-Child Cohort Active Surveillance Initiative (CAMCCO): Comparisons between Quebec, Manitoba, Saskatchewan, and Alberta
PLoS ONE
B{\'e}rard, A. and Kaul, P. and Eltonsy, S. and Winquist, B. and Chateau, D. and Hawken, S. and Sprague, A. and Walker, M. and Bernatsky, S. and Abrahamowicz, M. and de Moura, C.S. and Vinet, ?. and Carleton, B. and Hanley, G. and Oberlander, T. and Sheehy, O. and Gomez, Y.H. and Gorgui, J. and Savu, A.
DOI: 10.1371/journal.pone.0274355
2022Ensuring Equity and Inclusion in Virtual Care Best Practices for Diverse Populations of Youth with Chronic Pain
Healthcare quarterly (Toronto, Ont.)
Birnie, K.A. and Killackey, T. and Backlin, G. and Gavin, F. and Harris, C. and Jordan, I. and Kim, L. and Marianayagam, J. and Swidrovich, J. and Lalonde, C. and Tunji-Ajayi, L. and Oberlander, T. and Kirby-Allen, M. and Lambert, S. and Siden, H. and Swidrovich, J. and Noel, M. and Lalloo, C. and Stinson, J.
DOI: 10.12927/hcq.2022.26778
2022Data visualization as an intervention for pediatric chronic pain: a pilot feasibility study protocol for a randomized controlled crossover trial
Pilot and Feasibility Studies
Boerner, K.E. and Desai, U. and MacLean, K.E. and Munzner, T. and Foladare, H. and Gill, J. and Oberlander, T.F.
DOI: 10.1186/s40814-022-01170-5
2022COVID-19 Vaccine Intentions and Perceptions Among Public School Staff of the Greater Vancouver Metropolitan Area, British Columbia, Canada
Frontiers in Public Health
Watts, A.W. and Hutchison, S.M. and Bettinger, J.A. and Gadermann, A. and Oberle, E. and Oberlander, T.F. and Goldfarb, D.M. and Lavoie, P.M. and M{\^a}sse, L.C.
DOI: 10.3389/fpubh.2022.832444
2022Adaptive behavior, sleep, and physical activity in adolescents with fetal alcohol spectrum disorder
Research in Developmental Disabilities
Hammond, L. and Joly, V. and Kapasi, A. and Kryska, K. and Andrew, G. and Oberlander, T.F. and Pei, J. and Rasmussen, C.
DOI: 10.1016/j.ridd.2022.104366
2022The Impact of COVID-19 on Maternal Mental Health during Pregnancy: A Comparison between Canada and China within the CONCEPTION Cohort
International Journal of Environmental Research and Public Health
Pag{\`e}s, N. and Gorgui, J. and Wang, C. and Wang, X. and Zhao, J.-P. and Tchuente, V. and Lacasse, A. and C{\^o}t{\'e}, S. and King, S. and Muanda, F. and Mufike, Y. and Boucoiran, I. and Nuyt, A.M. and Quach, C. and Ferreira, E. and Kaul, P. and Winquist, B. and O?Donnell, K.J. and Eltonsy, S. and Chateau, D. and Hanley, G. and Oberlander, T. and Kassai, B. and Mainbourg, S. and Bernatsky, S. and Vinet, ?. and Brodeur-Doucet, A. and Demers, J. and Richeb{\'e}, P. and Zaphiratos, V. and B{\'e}rard, A.
DOI: 10.3390/ijerph191912386
2022The development of a patient decision aid to reduce decisional conflict about antidepressant use in pregnancy
BMC Medical Informatics and Decision Making
Hussain-Shamsy, N. and Somerton, S. and Stewart, D.E. and Grigoriadis, S. and Metcalfe, K. and Oberlander, T.F. and Schram, C. and Taylor, V.H. and Dennis, C.-L. and Vigod, S.N.
DOI: 10.1186/s12911-022-01870-1
2022Somatization in Adolescents With Persistent Symptoms After Concussion: A Retrospective Chart Review
The Journal of neuropsychiatry and clinical neurosciences
Green, K.E. and Purtzki, J. and Chapman, A. and Oberlander, T.F. and Silverberg, N.D. and Dhariwal, A.K.
DOI: 10.1176/appi.neuropsych.21070169
2022Adolescents with solid organ transplant: Using the BRIEF2 parent-report and self-report to measure parent-child agreement and everyday executive function
Applied Neuropsychology: Child
Hutchison, S.M. and Rathgeber, S.L. and De Souza, A.M. and Blydt-Hansen, T. and Mâsse, L.C. and Armstrong, K.R. and Oberlander, T.F.
DOI: 10.1080/21622965.2020.1800468
2022A text messaging intervention and quality of life in adolescents with solid organ transplants
Pediatric Transplantation
Rathgeber, S.L. and Hutchison, S.M. and De Souza, A.-M. and Lester, R. and Blydt-Hansen, T. and Human, D.G. and Guttman, O. and Oberlander, T. and Armstrong, K.R.
DOI: 10.1111/petr.14219
2022A cross-sectional study of the relationship between CYP2D6 and CYP2C19 variations and depression symptoms, for women taking SSRIs during pregnancy
Archives of Women's Mental Health
Hippman, C. and Slomp, C. and Morris, E. and Batallones, R. and Inglis, A. and Carrion, P. and Brain, U. and Higginson, M. and Wright, G.E.B. and Balneaves, L.G. and Ryan, D. and Nislow, C. and Ross, C.J.D. and Gaedigk, A. and Oberlander, T.F. and Austin, J.
DOI: 10.1007/s00737-021-01149-w
2022Profiling placental DNA methylation associated with maternal SSRI treatment during pregnancy
Scientific Reports
Inkster, A.M. and Konwar, C. and Pe{\~n}aherrera, M.S. and Brain, U. and Khan, A. and Price, E.M. and Schuetz, J.M. and Portales-Casamar, ?. and Burt, A. and Marsit, C.J. and Vaillancourt, C. and Oberlander, T.F. and Robinson, W.P.
DOI: 10.1038/s41598-022-26071-8
2022A multicentre Canadian survey of caregiver perspectives on COVID vaccine-related pain and stress for their family
British Journal of Pain
Ali, S. and Kammerer, E. and Thompson, G. and Mater, A. and Rajagopal, M. and Bone, J.N. and Birnie, K.A. and Oberlander, T. and Chambers, C.T. and Goldman, R.D.
DOI: 10.1177/20494637221090452
2022School staff and teachers during the second year of COVID-19: Higher anxiety symptoms, higher psychological distress, and poorer mental health compared to the general population
Journal of Affective Disorders Reports
Hutchison, S.M. and Watts, A. and Gadermann, A. and Oberle, E. and Oberlander, T.F. and Lavoie, P.M. and Mâsse, L.C.
DOI: 10.1016/j.jadr.2022.100335
2022Canadian surveillance study of complex regional pain syndrome in children
Pain
Baerg, K. and Tupper, S.M. and Chu, L.M. and Cooke, N. and Dick, B.D. and Dor{\'e}-Bergeron, M.-J. and Findlay, S. and Ingelmo, P.M. and Lamontagne, C. and Mesaroli, G. and Oberlander, T.F. and Poolacherla, R. and Spencer, A.O. and Stinson, J. and Finley, G.A.
DOI: 10.1097/j.pain.0000000000002482
2022Associations between Prenatal Exposure to Serotonergic Medications and Biobehavioral Stress Regulation: Protocol for a Systematic Review and Meta-analysis
JMIR Research Protocols
Zusman, E.Z. and Lavu, A. and Pawliuk, C. and Pawluski, J. and Hutchison, S.M. and Platt, R.W. and Oberlander, T.F.
DOI: 10.2196/33363
2022Preconception mental health and the relationship between antenatal depression or anxiety and gestational diabetes mellitus: a population-based cohort study
BMC pregnancy and childbirth
Thiele, G.A. and Ryan, D.M. and Oberlander, T.F. and Hanley, G.E.
DOI: 10.1186/s12884-022-05002-5
2022Maternal Schizophrenia and the Risk of a Childhood Chronic Condition
Schizophrenia bulletin
Vigod, S.N. and Ray, J.G. and Cohen, E. and Wilton, A.S. and Saunders, N.R. and Barker, L.C. and Berard, A. and Dennis, C.-L. and Holloway, A.C. and Morrison, K. and Oberlander, T.F. and Hanley, G. and Tu, K. and Brown, H.K.
DOI: 10.1093/schbul/sbac091
2022The PPD-ACT app in Canada: feasibility and a latent class analysis of participants with postpartum depression recruited to a psychiatric genetics study using a mobile application
BMC Psychiatry
Collaton, J. and Dennis, C.-L. and Taylor, V.H. and Grigoriadis, S. and Oberlander, T.F. and Frey, B.N. and Van Lieshout, R. and Guintivano, J. and Meltzer-Brody, S. and Kennedy, J.L. and Vigod, S.N.
DOI: 10.1186/s12888-022-04363-7
2022The influence of early-life residential exposure to different vegetation types and paved surfaces on early childhood development: A population-based birth cohort study
Environment International
Jarvis, I. and Sbihi, H. and Davis, Z. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Gergel, S.E. and Guhn, M. and Jerrett, M. and Koehoorn, M. and Nesbitt, L. and Oberlander, T.F. and Su, J. and van den Bosch, M.
DOI: 10.1016/j.envint.2022.107196
2022The association between prenatal greenspace exposure and Autism spectrum disorder, and the potentially mediating role of air pollution reduction: A population-based birth cohort study
Environment International
Pagalan, L. and Oberlander, T.F. and Hanley, G.E. and Rosella, L.C. and Bickford, C. and Weikum, W. and Lanphear, N. and Lanphear, B. and Brauer, M. and van den Bosch, M.
DOI: 10.1016/j.envint.2022.107445
2022Associations Between Prenatal Exposure to Serotonergic Medications and Biobehavioral Stress Regulation: Protocol for a Systematic Review and Meta-analysis (Preprint)
Enav Z Zusman and Alekhya Lavu and Colleen Pawliuk and Jodi Pawluski and Sarah M Hutchison and Robert W Platt and Tim F Oberlander
DOI: 10.2196/preprints.33363
09/2021Improving the regulation of medical cannabis in Canada to better serve pediatric patients,Améliorer la réglementation du cannabis médical au Canada pour mieux servir les patients pédiatriques
CMAJ
Huntsman, R.J. and Kelly, L.E. and Alcorn, J. and Appendino, J.P. and Bélanger, R.E. and Crooks, B. and Finkelstein, Y. and Gilpin, A. and Lewis, E. and Litalien, C. and Jacobs, J. and Moore-Hepburn, C. and Oberlander, T. and Rassekh, S.R. and Repetski, A.E. and Rieder, M.J. and Shackelford, A. and Siden, H. and Szafron, M. and T Jong, G.W. and Vaillancourt, R.
DOI: 10.1503/cmaj.202169-f
2021The association between natural environments and childhood mental health and development: A systematic review and assessment of different exposure measurements
International Journal of Hygiene and Environmental Health
Davis, Z. and Guhn, M. and Jarvis, I. and Jerrett, M. and Nesbitt, L. and Oberlander, T. and Sbihi, H. and Su, J. and van den Bosch, M.
DOI: 10.1016/j.ijheh.2021.113767
2021Prenatal stress and child development: The future that lies ahead
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_21
2021Prenatal antidepressant exposure and child development at kindergarten age: a population-based study
Pediatric Research
Park, M. and Hanley, G.E. and Guhn, M. and Oberlander, T.F.
DOI: 10.1038/s41390-020-01269-6
2021Perinatal selective serotonin reuptake inhibitor (SSRI) and other antidepressant exposure effects on anxiety and depressive behaviors in offspring: A review of findings in humans and rodent models
Reproductive Toxicology
Hutchison, S.M. and Mâsse, L.C. and Pawluski, J.L. and Oberlander, T.F.
DOI: 10.1016/j.reprotox.2020.11.013
2021Improving the regulation of medical cannabis in Canada to better serve pediatric patients
CMAJ
Huntsman, R.J. and Kelly, L.E. and Alcorn, J. and Appendino, J.P. and Bélanger, R.E. and Crooks, B. and Finkelstein, Y. and Gilpin, A. and Lewis, E. and Litalien, C. and Jacobs, J. and Moore-Hepburn, C. and Oberlander, T. and Rassekh, S.R. and Repetski, A.E. and Rieder, M.J. and Shackelford, A. and Siden, H. and Szafron, M. and T'Jong, G.W. and Vaillancourt, R.
DOI: 10.1503/cmaj.202169
2021The other side of prenatal depression: Developmental outcomes associated with antidepressant medication therapy
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_19
2021Prenatal stress and child development-pathways, mechanisms and interventions
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_1
2021Impact of the COVID-19 Pandemic on Maternal Mental Health during Pregnancy: The CONCEPTION Study – Phase I
SSRN
Bérard, A. and Lacasse, A. and Gomez, Y.-H. and Gorgui, J. and Côté, S.M. and King, S. and Tchuente, V. and Muanda, F.T. and Lumu, Y.M. and Boucoiran, I. and Nuyt, A.-M. and Quach, C.T. and Ferreira, E. and Kaul, P. and Winquist, B. and O?Donnell, K.J. and Eltonsy, S. and Chateau, D. and Zhao, J.-P. and Hanley, G.E. and Oberlander, T.F. and Kassai, B. and Mainbourg, S. and Bernatsky, S. and Vinet, ?. and Brodeur-Doucet, A. and Demers, J. and Richebé, P. and Zaphiratos, V. and Wang, C. and Wang, X.
DOI: 10.2139/ssrn.3777974
2021Assessing the association between lifetime exposure to greenspace and early childhood development and the mediation effects of air pollution and noise in Canada: a population-based birth cohort study
The Lancet. Planetary health
Jarvis, I. and Davis, Z. and Sbihi, H. and Brauer, M. and Czekajlo, A. and Davies, H.W. and Gergel, S.E. and Guhn, M. and Jerrett, M. and Koehoorn, M. and Oberlander, T.F. and Su, J. and van den Bosch, M.
DOI: 10.1016/S2542-5196(21)00235-7
2021Antidepressant exposure in pregnancy and child sensorimotor and visuospatial development: Antidepressants and child development
Journal of Psychiatric Research
Galbally, M. and Watson, S.J. and Spigset, O. and Boyce, P. and Oberlander, T.F. and Lewis, A.J.
DOI: 10.1016/j.jpsychires.2020.11.035
2021The Association between Cumulative Lifetime Exposure to Greenspace and Early Childhood Development – Is the Relation Mediated by Reduction in Air Pollution and Noise?
SSRN
DOI: 10.2139/ssrn.3831160
2021Preliminary insights into the genetic architecture of postpartum depressive symptom severity using polygenic risk scores
Personalized Medicine in Psychiatry
Pouget, J.G. and Taylor, V.H. and Dennis, C.-L. and Grigoriadis, S. and Oberlander, T. and Frey, B.N. and Van Lieshout, R. and Guintivano, J. and Meltzer-Brody, S. and Kennedy, J.L. and Vigod, S.N.
DOI: 10.1016/j.pmip.2021.100081
2021Association of Epidural Analgesia during Labor and Delivery with Autism Spectrum Disorder in Offspring
JAMA - Journal of the American Medical Association
Hanley, G.E. and Bickford, C. and Ip, A. and Lanphear, N. and Lanphear, B. and Weikum, W. and Zwaigenbaum, L. and Oberlander, T.F.
DOI: 10.1001/jama.2021.14986
2021The microbiome-gut-brain axis: A new window to view the impact of prenatal stress on early neurodevelopment
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1_8
2021Prenatal Stress and Child Development
Prenatal Stress and Child Development
DOI: 10.1007/978-3-030-60159-1
2021Prenatal antidepressant exposure and sex differences in neonatal corpus callosum microstructure
Developmental Psychobiology
Campbell, K.S.J. and Williams, L.J. and Bjornson, B.H. and Weik, E. and Brain, U. and Grunau, R.E. and Miller, S.P. and Oberlander, T.F.
DOI: 10.1002/dev.22125
2021Maternal Serotonin Reuptake Inhibitor Antidepressants Have Acute Effects on Fetal Heart Rate Variability in Late Gestation
Frontiers in Psychiatry
Campbell, K.S.J. and Collier, A.C. and Irvine, M.A. and Brain, U. and Rurak, D.W. and Oberlander, T.F. and Lim, K.I.
DOI: 10.3389/fpsyt.2021.680177
2021Correspondence: Adolescents during COVID-19: Youth with disabilities more likely to report challenges with anxiety and mental health
Journal of Affective Disorders Reports
Hutchison, S.M. and Holley, P. and Manuel, A. and Mâsse, L.C. and Oberlander, T.F. and Jedwab, J.
DOI: 10.1016/j.jadr.2020.100072
2021Prenatal exposure to maternal depression is related to the functional connectivity organization underlying emotion perception in 8-10-month-old infants – Preliminary findings
Infant Behavior and Development
Rotem-Kohavi, N. and Virji-Babul, N. and Oberlander, T.F.
DOI: 10.1016/j.infbeh.2021.101545
2021Epidural Analgesia and Autism Spectrum Disorder Risk - The Challenges Inherent in Complex Observational Research
JAMA Pediatrics
Hanley, G.E. and Ip, A. and Oberlander, T.F.
DOI: 10.1001/jamapediatrics.2021.0382
2021Symptoms, adverse events, and outcomes in the use of medicinal cannabis in children and adolescents with autism spectrum disorder: a scoping review protocol.
JBI evidence synthesis
Fletcher S and Pawliuk C and Ip A and Oberlander T and Siden H
DOI: 10.11124/jbies-20-00001
PubMed: 33165173
11/2020Effects of maternal depression and prenatal SSRI exposure on executive functions and susceptibility to household chaos in 6-year-old children: prospective cohort study
BJPsych Open
Gurpreet Dhaliwal and Whitney M. Weikum and Alexia Jolicoeur-Martineau and Ursula Brain and Ruth E. Grunau and Tim F. Oberlander
DOI: 10.1192/bjo.2020.73
09/2020The PPD-ACT App: Feasibility of a mobile application for recruiting women with postpartum depression and psychosis to a psychiatric genetics study (Preprint)
Joanna Collaton and Cindy-Lee Dennis and Valerie H Taylor and Sophie Grigoriadis and Tim F Oberlander and Benicio N Frey and Ryan Van Lieshout and Jerry Guintivano and Samantha Meltzer-Brody and James L Kennedy and Simone N Vigod
DOI: 10.2196/preprints.24327
09/2020Plasma Choline Concentration Is Positively Correlated with Visual Acuity in 18-Month Old Toddlers: Preliminary Findings.
Current developments in nutrition
Montgomery S and Rossen L and Zibrik D and Dyer R and Oberlander T and Lamers Y
05/2020Nutritional Status in Breastfed 18-Month Old Toddlers: Cross-Sectional Findings.
Current developments in nutrition
Montgomery S and Ho G and Rossen L and Zibrik D and Dyer R and Oberlander T and Lamers Y
05/2020Blood DHA, Choline, and Lutein Concentrations and Their Correlation with Cognitive and Behavioral Outcomes in 18-Month Old Toddlers: Preliminary Findings.
Current developments in nutrition
Rossen L and Montgomery S and Zibrik D and Dyer R and Oberlander T and Lamers Y
05/2020Advanced neuroimaging: A window into the neural correlates of fetal programming related to prenatal exposure to maternal depression and SSRIs
Seminars in Perinatology
Rotem-Kohavi, N. and Williams, L.J. and Oberlander, T.F.
DOI: 10.1016/j.semperi.2020.151223
2020Correction : In Utero Exposure to Citalopram Mitigates Maternal Stress Effects on Fetal Brain Development (ACS Chem. Neurosci. (2019) 10:7 (3307-3317) DOI: 10.1021/acschemneuro.9b00180)
ACS Chemical Neuroscience
Velasquez, J.C. and Zhao, Q. and Chan, Y. and Galindo, L.C.M. and Simasotchi, C. and Wu, D. and Hou, Z. and Herod, S.M. and Oberlander, T.F. and Gil, S. and Fournier, T. and Burd, I. and Andrews, A.M. and Bonnin, A.
DOI: 10.1021/acschemneuro.9b00683
2020Conditioned Placebo- and Nocebo-Like Effects in Adolescents: The Role of Conscious Awareness, Sensory Discrimination, and Executive Function
Frontiers in Psychiatry
Neuenschwander, R. and Weik, E. and Tipper, C.M. and Jensen, K. and Oberlander, T.F.
DOI: 10.3389/fpsyt.2020.586455
2020Differences in White Matter Microstructure among Children with Developmental Coordination Disorder
JAMA Network Open
Zwicker, J.G. and Brown-Lum, M. and Izadi-Najafabadi, S. and Oberlander, T.F. and Rauscher, A. and Zwicker, J.G.
DOI: 10.1001/jamanetworkopen.2020.1184
2020The Association between Antidepressant Exposure and Birth Defects-Are We There Yet?
JAMA Psychiatry
Wisner, K.L. and Oberlander, T.F. and Huybrechts, K.F.
DOI: 10.1001/jamapsychiatry.2020.1512
2020Socieconomic status and psychotropic medicine use during pregnancy: a population-based study in British Columbia, Canada
Archives of Women's Mental Health
Hanley, G.E. and Park, M. and Oberlander, T.F.
DOI: 10.1007/s00737-020-01034-y
2020Identification of Pediatric Autism Spectrum Disorder Cases Using Health Administrative Data
Autism Research
Bickford, C.D. and Oberlander, T.F. and Lanphear, N.E. and Weikum, W.M. and Janssen, P.A. and Ouellette-Kuntz, H. and Hanley, G.E.
DOI: 10.1002/aur.2252
2020Decision-making about antidepressant medication use in pregnancy: A comparison between women making the decision in the preconception period versus in pregnancy
BMC Psychiatry
Barker, L.C. and Dennis, C.-L. and Hussain-Shamsy, N. and Stewart, D.E. and Grigoriadis, S. and Metcalfe, K. and Oberlander, T.F. and Schram, C. and Taylor, V.H. and Vigod, S.N.
DOI: 10.1186/s12888-020-2478-8
2020“Placebo by Proxy” and “Nocebo by Proxy” in Children: A Review of Parents' Role in Treatment Outcomes
Frontiers in Psychiatry
Czerniak, E. and Oberlander, T.F. and Weimer, K. and Kossowsky, J. and Enck, P.
DOI: 10.3389/fpsyt.2020.00169
2020The role of glucocorticoid and mineralocorticoid receptor DNA methylation in antenatal depression and infant stress regulation
Psychoneuroendocrinology
Galbally, M. and Watson, S.J. and van IJzendoorn, M. and Saffery, R. and Ryan, J. and de Kloet, E.R. and Oberlander, T.F. and Lappas, M. and Lewis, A.J.
DOI: 10.1016/j.psyneuen.2020.104611
2020126 The Canadian Neonatal Brain Platform: A three-pillar approach.
Paediatrics & Child Health
Luck D and Ding Y and Luu TM and Oberlander T and Grunau R and Miller S and Lodygensky G
05/2019Alterations in Resting-State Networks Following In Utero Selective Serotonin Reuptake Inhibitor Exposure in the Neonatal Brain
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Rotem-Kohavi, N. and Williams, L.J. and Virji-Babul, N. and Bjornson, B.H. and Brain, U. and Werker, J.F. and Grunau, R.E. and Miller, S.P. and Oberlander, T.F.
DOI: 10.1016/j.bpsc.2018.08.004
2019Transcranial direct current stimulation (tDCS) for depression in pregnancy: A pilot randomized controlled trial
Brain Stimulation
Vigod, S.N. and Murphy, K.E. and Dennis, C.-L. and Oberlander, T.F. and Ray, J.G. and Daskalakis, Z.J. and Blumberger, D.M.
DOI: 10.1016/j.brs.2019.06.019
2019Calmer: A robot for managing acute pain effectively in preterm infants in the neonatal intensive care unit
Pain Reports
Holsti, L. and MacLean, K. and Oberlander, T. and Synnes, A. and Brant, R.
DOI: 10.1097/PR9.0000000000000727
2019Selective serotonin reuptake inhibitor effects on neural biomarkers of perinatal depression
Archives of Women's Mental Health
Pawluski, J.L. and Brain, U. and Hammond, G.L. and Oberlander, T.F.
DOI: 10.1007/s00737-018-0931-1
2019Evaluating pain in cerebral palsy: comparing assessment tools using the International Classification of Functioning, Disability and Health
Disability and Rehabilitation
Schiariti, V. and Oberlander, T.F.
DOI: 10.1080/09638288.2018.1472818
2019Myelin Water Fraction Imaging of the Brain in Children with Prenatal Alcohol Exposure
Alcoholism: Clinical and Experimental Research
McLachlan, K. and Vavasour, I. and MacKay, A. and Brain, U. and Oberlander, T. and Loock, C. and Reynolds, J.N. and Beaulieu, C.
DOI: 10.1111/acer.14024
2019Hub distribution of the brain functional networks of newborns prenatally exposed to maternal depression and SSRI antidepressants
Depression and Anxiety
Rotem-Kohavi, N. and Williams, L.J. and Muller, A.M. and Abdi, H. and Virji-Babul, N. and Bjornson, B.H. and Brain, U. and Werker, J.F. and Grunau, R.E. and Miller, S.P. and Oberlander, T.F.
DOI: 10.1002/da.22906
2019A patient decision aid for antidepressant use in pregnancy: Pilot randomized controlled trial
Journal of Affective Disorders
Vigod, S.N. and Hussain-Shamsy, N. and Stewart, D.E. and Grigoriadis, S. and Metcalfe, K. and Oberlander, T.F. and Schram, C. and Taylor, V.H. and Dennis, C.-L.
DOI: 10.1016/j.jad.2019.01.051
2019In utero exposure to citalopram mitigates maternal stress effects on fetal brain development
ACS Chemical Neuroscience
Velasquez, J.C. and Zhao, Q. and Chan, Y. and Galindo, L.C.M. and Simasotchi, C. and Wu, D. and Hou, Z. and Herod, S.M. and Oberlander, T.F. and Gil, S. and Fournier, T. and Burd, I. and Andrews, A.M. and Bonnin, A.
DOI: 10.1021/acschemneuro.9b00180
2019Impact of prenatal selective serotonin reuptake inhibitor antidepressant exposure and maternal mood on physical activity, dietary intake, and markers of adiposity at age 6 years
Journal of Developmental and Behavioral Pediatrics
Hutchison, S.M. and Mâsse, L.C. and Glier, M.B. and Brain, U. and Devlin, A.M. and Oberlander, T.F.
DOI: 10.1097/DBP.0000000000000658
2019A 6-year longitudinal study: Are maternal depressive symptoms and Selective Serotonin Reuptake Inhibitor (SSRI) antidepressant treatment during pregnancy associated with everyday measures of executive function in young children?
Early Human Development
Hutchison, S.M. and Mâsse, L.C. and Brain, U. and Oberlander, T.F.
DOI: 10.1016/j.earlhumdev.2018.10.009
2019Risk factors for hospitalizations associated with depression among women during the years around a birth: A retrospective cohort study
International Journal of Population Data Science
Fairthorne, J.C. and Hanley, G.E. and Brant, R. and Oberlander, T.F.
DOI: 10.23889/ijpds.v4i1.453
2019Prevalence and characteristics of adults with fetal alcohol spectrum disorder in corrections: A Canadian case ascertainment study
BMC Public Health
McLachlan, K. and McNeil, A. and Pei, J. and Brain, U. and Andrew, G. and Oberlander, T.F.
DOI: 10.1186/s12889-018-6292-x
2019Prenatal SSRI antidepressant use and maternal internalizing symptoms during pregnancy and postpartum: Exploring effects on infant temperament trajectories for boys and girls
Journal of Affective Disorders
Erickson, N.L. and Hancock, G.R. and Oberlander, T.F. and Brain, U. and Grunau, R.E. and Gartstein, M.A.
DOI: 10.1016/j.jad.2019.08.003
2019Association of Prenatal Exposure to Air Pollution with Autism Spectrum Disorder
JAMA Pediatrics
Pagalan, L. and Bickford, C. and Weikum, W. and Lanphear, B. and Brauer, M. and Lanphear, N. and Hanley, G.E. and Oberlander, T.F. and Winters, M.
DOI: 10.1001/jamapediatrics.2018.3101
2019Children's stress regulation mediates the association between prenatal maternal mood and child executive functions for boys, but not girls
Development and Psychopathology
Neuenschwander, R. and Hookenson, K. and Brain, U. and Grunau, R.E. and Devlin, A.M. and Weinberg, J. and Diamond, A. and Oberlander, T.F.
DOI: 10.1017/S095457941800041X
2018Socioeconomic status and treatment of depression during pregnancy: A retrospective population-based cohort study in British Columbia, Canada
Archives of Women's Mental Health
Hanley, G.E. and Park, M. and Oberlander, T.F.
DOI: 10.1007/s00737-018-0866-6
2018In-utero Selective Serotonin Reuptake Inhibitor Antidepressant Exposure: Fetal Programing and Developmental Interactions With Context
Clinical Pharmacology and Therapeutics
Park, M. and Oberlander, T.F.
DOI: 10.1002/cpt.1134
2018Perinatal selective serotonin reuptake inhibitor medication (SSRI) effects on social behaviors, neurodevelopment and the epigenome
Neuroscience and Biobehavioral Reviews
Gemmel, M. and Bögi, E. and Ragan, C. and Hazlett, M. and Dubovicky, M. and van den Hove, D.L. and Oberlander, T.F. and Charlier, T.D. and Pawluski, J.L.
DOI: 10.1016/j.neubiorev.2017.04.023
2018Maternal depression trajectories from pregnancy to 3 years postpartum are associated with children’s behavior and executive functions at 3 and 6 years
Archives of Women's Mental Health
Park, M. and Brain, U. and Grunau, R.E. and Diamond, A. and Oberlander, T.F.
DOI: 10.1007/s00737-017-0803-0
2018Perinatal selective serotonin reuptake inhibitor (SSRI) effects on body weight at birth and beyond: A review of animal and human studies
Reproductive Toxicology
Hutchison, S.M. and Mâsse, L.C. and Pawluski, J.L. and Oberlander, T.F.
DOI: 10.1016/j.reprotox.2018.02.004
2018Born to be Wise: A population registry data linkage protocol to assess the impact of modifiable early-life environmental exposures on the health and development of children
BMJ Open
Van Den Bosch, M. and Brauer, M. and Burnett, R. and Davies, H.W. and Davis, Z. and Guhn, M. and Jarvis, I. and Nesbitt, L. and Oberlander, T. and Rugel, E. and Sbihi, H. and Su, J.G. and Jerrett, M.
DOI: 10.1136/bmjopen-2018-026954
2018Variations from morning to afternoon of middle cerebral and umbilical artery blood flow, and fetal heart rate variability, and fetal characteristics in the normally developing fetus
Journal of Clinical Ultrasound
Avitan, T. and Sanders, A. and Brain, U. and Rurak, D. and Oberlander, T.F. and Lim, K.
DOI: 10.1002/jcu.22569
2018Depressed Women of Low Socioeconomic Status Have High Numbers of Physician Visits in the Year Before Pregnancy: Implications for Care
Journal of Clinical Medicine Research
Jenny Fairthorne and Gillian E. Hanley and Tim F. Oberlander
DOI: 10.14740/jocmr3377w
2018HOUSEHOLD CHAOS, MATERNAL DEPRESSION AND PRENATAL SSRI EXPOSURE INTERACT TO AFFECT EXECUTIVE FUNCTION OF 6 YEAR OLD CHILDREN.
Paediatrics & Child Health
Dhaliwal G and Weikum W and Jolicoeur-Martineau A and Brain U and Grunau R and Oberlander T
DOI: 10.1093/pch/pxx086.019
05/2017The Risk of Teenage Motherhood Decreases in A Dose Response Fashion With Increasing SES: A Population-Based Study From British Columbia, Canada
JWHG
Jenny Fairthorne
DOI: 10.17303/jwhg.2017.4.104
03/2017Post-Partum Depression and Infant Crying Behavior
Encyclopedia on Early Childhood Development
2017Unpacking the Heterogeneity of Cognitive Functioning in Children and Adolescents with Fetal Alcohol Spectrum Disorder: Determining the Role of Moderators and Strengths
Advances in Neurodevelopmental Disorders
McLachlan, K. and Paolozza, A. and Kully-Martens, K. and Portales-Casamar, E. and Pavlidis, P. and Andrew, G. and Hanlon-Dearman, A. and Loock, C. and McFarlane, A. and Nikkel, S.M. and Pei, J. and Oberlander, T.F. and Samdup, D. and Reynolds, J.N. and Rasmussen, C.
DOI: 10.1007/s41252-017-0034-4
2017Predictors of Recovery from Depression and Anxiety in Women: A Longitudinal Study from Childbirth to 6 Years
Canadian Journal of Psychiatry
Shankar, R. and Badker, R. and Brain, U. and Oberlander, T.F. and Misri, S.
DOI: 10.1177/0706743716677725
2017Infants and adults have similar regional functional brain organization for the perception of emotions
Neuroscience Letters
Rotem-Kohavi, N. and Oberlander, T.F. and Virji-Babul, N.
DOI: 10.1016/j.neulet.2017.04.031
2017Developmental changes in serotonin signaling: Implications for early brain function, behavior and adaptation
Neuroscience
Brummelte, S. and Mc Glanaghy, E. and Bonnin, A. and Oberlander, T.F.
DOI: 10.1016/j.neuroscience.2016.02.037
2017Variations in Neurodevelopmental Outcomes in Children with Prenatal SSRI Antidepressant Exposure
Birth Defects Research
Rotem-Kohavi, N. and Oberlander, T.F.
DOI: 10.1002/bdr2.1076
2017Response to “use of domperidone and risk of ventricular arrhythmia in the postpartum period: Getting to the heart of the matter”
Pharmacoepidemiology and Drug Safety
Smolina, K. and Morgan, S. and Mintzes, B. and Hanley, G. and Oberlander, T.
DOI: 10.1002/pds.4229
2017Developmental origins of self-regulation: Prenatal maternal stress and psychobiological development during childhood
Parental Stress and Early Child Development: Adaptive and Maladaptive Outcomes
DOI: 10.1007/978-3-319-55376-4_6
2017Disentangling maternal depression and antidepressant use during pregnancy as risks for autism in children
JAMA - Journal of the American Medical Association
Oberlander, T.F. and Zwaigenbaum, L.
DOI: 10.1001/jama.2017.3414
2017Afternoon cortisol provides a link between self-regulated anger and peer-reported aggression in typically developing children in the school context
Developmental Psychobiology
Oberle, E. and McLachlan, K. and Catherine, N.L.A. and Brain, U. and Schonert-Reichl, K.A. and Weinberg, J. and Oberlander, T.F.
DOI: 10.1002/dev.21522
2017Children’s stress regulation mediates the association between depressed and/or anxious prenatal maternal mood and child executive functions for boys, but not girls
Development and Psychopathology
2017Antenatal exposure to antidepressants is associated with altered brain development in very preterm-born neonates
Neuroscience
Podrebarac, S.K. and Duerden, E.G. and Chau, V. and Grunau, R.E. and Synnes, A. and Oberlander, T.F. and Miller, S.P.
DOI: 10.1016/j.neuroscience.2016.11.025
2017Postpartum domperidone use in British Columbia: a retrospective cohort study
CMAJ Open
K. Smolina and S. G. Morgan and G. E. Hanley and T. F. Oberlander and B. Mintzes
DOI: 10.9778/cmajo.20150067
01/2016Postpartum Hemorrhage and Use of Serotonin Reuptake Inhibitor Antidepressants in Pregnancy
Obstetrics and Gynecology
Hanley, G.E. and Smolina, K. and Mintzes, B. and Oberlander, T.F. and Morgan, S.G.
DOI: 10.1097/AOG.0000000000001200
2016Developmental Effects of Prenatal Selective Serotonin Reuptake Inhibitor Exposure in Perspective: Are We Comparing Apples to Apples?
Journal of the American Academy of Child and Adolescent Psychiatry
Oberlander, T.F. and Vigod, S.N.
DOI: 10.1016/j.jaac.2016.02.012
2016Fetal effects of in utero serotonin reuptake inhibitor (SRI) antidepressant exposure
Fetal Development: Research on Brain and Behavior, Environmental Influences, and Emerging Technologies
DOI: 10.1007/978-3-319-22023-9_18
2016SLC6A4 promoter region methylation and socio-emotional stress response in very preterm and full-term infants
Epigenomics
Montirosso, R. and Provenzi, L. and Giorda, R. and Fumagalli, M. and Morandi, F. and Sirgiovanni, I. and Pozzoli, U. and Grunau, R. and Oberlander, T.F. and Mosca, F. and Borgatti, R.
DOI: 10.2217/epi-2016-0010
2016Sculpting infant soothability: the role of prenatal SSRI antidepressant exposure and neonatal SLC6A4 methylation status
Developmental Psychobiology
Gartstein, M.A. and Hookenson, K.V. and Brain, U. and Devlin, A.M. and Grunau, R.E. and Oberlander, T.F.
DOI: 10.1002/dev.21414
2016Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome
Pharmacogenomics Journal
Hall, K.T. and Kossowsky, J. and Oberlander, T.F. and Kaptchuk, T.J. and Saul, J.P. and Wyller, V.B. and Fagermoen, E. and Sulheim, D. and Gjerstad, J. and Winger, A. and Mukamal, K.J.
DOI: 10.1038/tpj.2016.53
2016Dysregulation of the cortisol diurnal rhythm following prenatal alcohol exposure and early life adversity
Alcohol
McLachlan, K. and Rasmussen, C. and Oberlander, T.F. and Loock, C. and Pei, J. and Andrew, G. and Reynolds, J. and Weinberg, J.
DOI: 10.1016/j.alcohol.2016.03.003
2016The association between domperidone and ventricular arrhythmia in the postpartum period
Pharmacoepidemiology and Drug Safety
Smolina, K. and Mintzes, B. and Hanley, G.E. and Oberlander, T.F. and Morgan, S.G.
DOI: 10.1002/pds.4035
2016Pain
Health Care for People with Intellectual and Developmental Disabilities Across the Lifespan
DOI: 10.1007/978-3-319-18096-0_143
2016A patient decision aid for antidepressant use in pregnancy: Study protocol for a randomized controlled trial
Trials
Vigod, S. and Hussain-Shamsy, N. and Grigoriadis, S. and Howard, L.M. and Metcalfe, K. and Oberlander, T.F. and Schram, C. and Stewart, D.E. and Taylor, V.H. and Dennis, C.-L.
DOI: 10.1186/s13063-016-1233-4
2016Enhancing cognitive and social–emotional development through a simple-to-administer mindfulness-based school program for elementary school children: A randomized controlled trial.
Developmental Psychology
Kimberly A. Schonert-Reichl and Eva Oberle and Molly Stewart Lawlor and David Abbott and Kimberly Thomson and Tim F. Oberlander and Adele Diamond
DOI: 10.1037/a0038454
01/2015Prenatal exposure to serotonin reuptake inhibitor antidepressants and childhood behavior
Pediatric Research
Hanley, G.E. and Brain, U. and Oberlander, T.F.
DOI: 10.1038/pr.2015.77
2015Trends and determinants of prescription drug use during pregnancy and postpartum in British Columbia, 2002-2011: A population-based cohort study
PLoS ONE
Smolina, K. and Hanley, G.E. and Mintzes, B. and Oberlander, T.F. and Morgan, S.
DOI: 10.1371/journal.pone.0128312
2015Prenatal antidepressant exposure associated with CYP2E1 DNA methylation change in neonates
Epigenetics
Gurnot, C. and Martin-Subero, I. and Mah, S.M. and Weikum, W. and Goodman, S.J. and Brain, U. and Werker, J.F. and Kobor, M.S. and Esteller, M. and Oberlander, T.F. and Hensch, T.K.
DOI: 10.1080/15592294.2015.1026031
2015A randomized controlled trial of eye shields and earmuffs to reduce pain response of preterm infants
Journal of Neonatal Nursing
Aita, M. and Goulet, C. and Oberlander, T.F. and Snider, L. and Johnston, C.
DOI: 10.1016/j.jnn.2014.11.004
2015Do We Know If They Work and If They Are Safe: Second-Generation Antipsychotics for Treatment of Autism Spectrum Disorders and Disruptive Behavior Disorders in Children and Adolescents
The Science and Ethics of Antipsychotic Use in Children
DOI: 10.1016/B978-0-12-800016-8.00003-9
2015Evaluation of the Neurobehavioral Screening Tool in Children with Fetal Alcohol Spectrum Disorder (FASD)
Journal of Population Therapeutics and Clinical Pharmacology
PubMed: 24897061
05/2014Rising antipsychotic prescriptions for children and youth: cross-sectoral solutions for a multimodal problem
Canadian Medical Association Journal
N. Di Pietro and J. Illes and for the Canadian Working Group on Antipsychotic Medications and Children
DOI: 10.1503/cmaj.131604
03/2014The impact of maternal positive and negative affect on fetal physiology and diurnal patterns.
The Israel journal of psychiatry and related sciences
Hanley GE and Rurak D and Lim K and Brain U and Oberlander TF
PubMed: 25372560
01/2014Transcranial direct current stimulation (tDCS) for treatment of major depression during pregnancy: Study protocol for a pilot randomized controlled trial
Trials
Vigod, S. and Dennis, C.-L. and Daskalakis, Z. and Murphy, K. and Ray, J. and Oberlander, T. and Somerton, S. and Hussain-Shamsy, N. and Blumberger, D.
DOI: 10.1186/1745-6215-15-366
2014The effect of perinatal exposures on the infant: Antidepressants and depression
Best Practice and Research: Clinical Obstetrics and Gynaecology
Hanley, G.E. and Oberlander, T.F.
DOI: 10.1016/j.bpobgyn.2013.09.001
2014The symphonic structure of childhood stress reactivity: Patterns of sympathetic, parasympathetic, and adrenocortical responses to psychological challenge
Development and Psychopathology
Quas, J.A. and Yim, I.S. and Oberlander, T.F. and Nordstokke, D. and Essex, M.J. and Armstrong, J.M. and Bush, N. and Obradovi?, J. and Boyce, W.T.
DOI: 10.1017/S0954579414000480
2014The impact of maternal positive and negative affect on fetal physiology and diurnal patterns
Israel Journal of Psychiatry and Related Sciences
Hanley, G.E. and Rurak, D. and Lim, K. and Brain, U. and Oberlander, T.F.
2014Neonatal pain and COMT Val158Met genotype in relation to serotonin transporter (SLC6A4) promoter methylation in very preterm children at school age
Frontiers in Behavioral Neuroscience
Cecil M. Y. Chau and Manon Ranger and Dian Sulistyoningrum and Angela M. Devlin and Tim F. Oberlander and Ruth E. Grunau
DOI: 10.3389/fnbeh.2014.00409
2014Evaluation of the neurobehavioral screening tool in children with fetal alcohol spectrum disorders (FASD)
Journal of Population Therapeutics and Clinical Pharmacology
LaFrance, M.-A. and McLachlan, K. and Nash, K. and Andrew, G. and Loock, C. and Oberlander, T.F. and Koren, G. and Rasmussen, C.
2014Pain in children with autism
Mental Health and Pain: Somatic and Psychiatric Components of Pain in Mental Health
DOI: 10.1007/978-2-8178-0414-9_12
2014Maternal and Fetal Factors That Influence Prenatal Exposure to Selective Serotonin Reuptake Inhibitor Antidepressants
Psychopharmacology and Pregnancy
DOI: 10.1007/978-3-642-54562-7_4
2014Biomarkers of pain: physiological indices of pain reactivity in infants and children
Oxford Medicine Online
Susanne Brummelte and Tim F. Oberlander and Kenneth D. Craig
DOI: 10.1093/med/9780199642656.003.0038
11/2013Infant developmental outcomes following prenatal exposure to antidepressants, and maternal depressed mood and positive affect
Early Human Development
Hanley, G.E. and Brain, U. and Oberlander, T.F.
DOI: 10.1016/j.earlhumdev.2012.12.012
2013Physician variability in treating pain and irritability of unknown origin in children with severe neurological Impairment
Pain Research and Management
Siden, H.B. and Carleton, B.C. and Oberlander, T.F.
DOI: 10.1155/2013/193937
2013Factors impacting decisions to decline or adhere to antidepressant medication in perinatal women with mood and anxiety disorders
Depression and Anxiety
Misri, S. and Eng, A.B. and Abizadeh, J. and Blackwell, E. and Spidel, A. and Oberlander, T.F.
DOI: 10.1002/da.22137
2013Antidepressant use during pregnancy and serotonin transporter genotype (SLC6A4) Affect newborn serum reelin levels
Developmental Psychobiology
Brummelte, S. and Galea, L.A.M. and Devlin, A.M. and Oberlander, T.F.
DOI: 10.1002/dev.21056
2013Intervention Minimizing Preterm Infants' Exposure to NICU Light and Noise
Clinical Nursing Research
Aita, M. and Johnston, C. and Goulet, C. and Oberlander, T.F. and Snider, L.
DOI: 10.1177/1054773812469223
2013The impact of prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and maternal mood on mother-infant interactions at 3 months of age
Infant Behavior and Development
Weikum, W.M. and Mayes, L.C. and Grunau, R.E. and Brain, U. and Oberlander, T.F.
DOI: 10.1016/j.infbeh.2013.04.001
2013Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure and serotonin transporter promoter genotype (SLC6A4) influence executive functions at 6 years of age
Frontiers in Cellular Neuroscience
Weikum, W.M. and Brain, U. and Chau, C.M.Y. and Grunau, R.E. and Boyce, W.T. and Diamond, A. and Oberlander, T.F.
DOI: 10.3389/fncel.2013.00180
2013Pain in Children with Disabilities
Encyclopedia of Pain
Kenneth D. Craig and Tim F. Oberlander
DOI: 10.1007/978-3-540-29805-2_3090
2013A tale of 2s: Optimizing maternal-child health in the context of antenatal maternal depression and antidepressant use
Canadian Journal of Psychiatry
Oberlander, T.F. and Wisner, K.L.
DOI: 10.1177/070674371205700901
2012Fetal serotonin reuptake inhibitor antidepressant exposure: Maternal and fetal factors
Canadian Journal of Psychiatry
Shea, A.K. and Oberlander, T.F. and Rurak, D.
DOI: 10.1177/070674371205700902
2012Fetal serotonin signaling: Setting pathways for early childhood development and behavior
Journal of Adolescent Health
Oberlander, T.F.
DOI: 10.1016/j.jadohealth.2012.04.009
2012Biopsychosocial determinants of treatment outcome for mood and anxiety disorders up to 8 months postpartum
Archives of Women's Mental Health
Misri, S. and Albert, G. and Abizadeh, J. and Kendrick, K. and Carter, D. and Ryan, D. and Oberlander, T.F.
DOI: 10.1007/s00737-012-0288-9
2012Prenatal SSRI exposure alters neonatal corticosteroid binding globulin, infant cortisol levels, and emerging HPA function
Psychoneuroendocrinology
Pawluski, J.L. and Brain, U.M. and Underhill, C.M. and Hammond, G.L. and Oberlander, T.F.
DOI: 10.1016/j.psyneuen.2011.11.011
2012Frontal EEG/ERP correlates of attentional processes, cortisol and motivational states in adolescents from lower and higher socioeconomic status
Frontiers in Human Neuroscience
Amedeo D'Angiulli and Joanne Weinberg and Tim F. Oberlander and Ruth E. Grunau and Clyde Hertzman and Stefania Maggi
DOI: 10.3389/fnhum.2012.00306
2012Third trimester fetal pulmonary artery Doppler blood flow velocity characteristics following prenatal selective serotonin reuptake inhibitor (SSRI) exposure
Early Human Development
Lim, K. and Sanders, A. and Brain, U. and Riggs, W. and Oberlander, T.F. and Rurak, D.
DOI: 10.1016/j.earlhumdev.2012.01.004
2012Neurodevelopmental outcomes following prenatal exposure to serotonin reuptake inhibitor antidepressants: A "social teratogen" or moderator of developmental risk?
Birth Defects Research Part A - Clinical and Molecular Teratology
Hanley, G.E. and Oberlander, T.F.
DOI: 10.1002/bdra.23032
2012Prenatal exposure to antidepressants and depressed maternal mood alter trajectory of infant speech perception
Proceedings of the National Academy of Sciences of the United States of America
Weikum, W.M. and Oberlander, T.F. and Hensch, T.K. and Werker, J.F.
DOI: 10.1073/pnas.1121263109
2012Focused attention, heart rate deceleration, and cognitive development in preterm and full-term infants
Developmental Psychobiology
Petrie Thomas, J.H. and Whitfield, M.F. and Oberlander, T.F. and Synnes, A.R. and Grunau, R.E.
DOI: 10.1002/dev.20597
2012Afternoon Cortisol in Elementary School Classrooms: Associations with Peer and Teacher Support and Child Behavior
School Mental Health
Catherine, N.L.A. and Schonert-Reichl, K.A. and Hertzman, C. and Oberlander, T.F.
DOI: 10.1007/s12310-012-9076-y
2012Reply to Klinger et al
Birth Defects Research Part A - Clinical and Molecular Teratology
Hanley, G.E. and Oberlander, T.F.
DOI: 10.1002/bdra.23095
2012Pediatric analgesic clinical trial designs, measures, and extrapolation: Report of an FDA Scientific Workshop
Pediatrics
DOI: 10.1542/peds.2010-3591
2012Reply
Acta Psychiatrica Scandinavica
Warburton, W. and Hertzman, C. and Oberlander, T.F.
DOI: 10.1111/j.1600-0447.2010.01643.x
2011Antidepressant use in children and adolescents: Practice touch points to guide paediatricians
Paediatrics and Child Health
Oberlander, T.F. and Miller, A.R.
DOI: 10.1093/pch/16.9.549
2011Third trimester fetal heart rate and doppler middle cerebral artery blood flow velocity characteristics during prenatal selective serotonin reuptake inhibitor exposure
Pediatric Research
Rurak, D. and Lim, K. and Sanders, A. and Brain, U. and Riggs, W. and Oberlander, T.F.
DOI: 10.1203/PDR.0b013e31821ba11a
2011Does breastfeeding reduce acute procedural pain in preterm infants in the neonatal intensive care unit? A randomized clinical trial
Pain
Holsti, L. and Oberlander, T.F. and Brant, R.
DOI: 10.1016/j.pain.2011.07.022
2011Pain in Individuals with Intellectual Disabilities
Clinical Pain Management: A Practical Guide
DOI: 10.1002/9781444329711.ch39
2010Prenatal exposure to maternal depressed mood and the MTHFR C677T variant affect SLC6A4 methylation in infants at birth
PLoS ONE
Devlin, A.M. and Brain, U. and Austin, J. and Oberlander, T.F.
DOI: 10.1371/journal.pone.0012201
2010Prenatal alcohol exposure alters biobehavioral reactivity to pain in newborns
Alcoholism: Clinical and Experimental Research
Oberlander, T.F. and Jacobson, S.W. and Weinberg, J. and Grunau, R.E. and Molteno, C.D. and Jacobson, J.L.
DOI: 10.1111/j.1530-0277.2009.01137.x
2010Physiological correlates of memory recall in infancy: Vagal tone, cortisol, and imitation in preterm and full-term infants at 6 months
Infant Behavior and Development
Haley, D.W. and Grunau, R.E. and Weinberg, J. and Keidar, A. and Oberlander, T.F.
DOI: 10.1016/j.infbeh.2009.10.007
2010Antenatal depression and anxiety affect postpartum parenting stress: A longitudinal, prospective study
Canadian Journal of Psychiatry
Misri, S. and Kendrick, K. and Oberlander, T.F. and Norris, S. and Tomfohr, L. and Zhang, H. and Grunau, R.E.
DOI: 10.1177/070674371005500405
2010A register study of the impact of stopping third trimester selective serotonin reuptake inhibitor exposure on neonatal health
Acta Psychiatrica Scandinavica
Warburton, W. and Hertzman, C. and Oberlander, T.F.
DOI: 10.1111/j.1600-0447.2009.01490.x
2010Prenatal effects of selective serotonin reuptake inhibitor antidepressants, serotonin transporter promoter genotype (SLC6A4), and maternal mood on child behavior at 3 years of age
Archives of Pediatrics and Adolescent Medicine
Oberlander, T.F. and Papsdorf, M. and Brain, U.M. and Misri, S. and Ross, C. and Grunau, R.E.
DOI: 10.1001/archpediatrics.2010.51
2010Cortisol, behavior, and heart rate reactivity to immunization pain at 4 months corrected age in infants born very preterm
Clinical Journal of Pain
Grunau, R.E. and Tu, M.T. and Whitfield, M.F. and Oberlander, T.F. and Weinberg, J. and Yu, W. and Thiessen, P. and Gosse, G. and Scheifele, D.
DOI: 10.1097/AJP.0b013e3181e5bb00
2010The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists
General Hospital Psychiatry
Kimberly A. Yonkers and Katherine L. Wisner and Donna E. Stewart and Tim F. Oberlander and Diana L. Dell and Nada Stotland and Susan Ramin and Linda Chaudron and Charles Lockwood
DOI: 10.1016/j.genhosppsych.2009.04.003
09/2009Pain in individuals with intellectual and developmental disabilities
Journal of Pain Management
Symons, F.J. and Oberlander, T.F. and Kehl, L.J.
2009Neonatal S100B protein levels after prenatal exposure to selective serotonin reuptake inhibitors
Pediatrics
Pawluski, J.L. and Galea, L.A.M. and Brain, U. and Papsdorf, M. and Oberlander, T.F.
DOI: 10.1542/peds.2009-0442
2009Depression during pregnancy: The potential impact of increased risk for fetal aneuploidy on maternal mood
Clinical Genetics
Hippman, C. and Oberlander, T.F. and Honer, W.G. and Misri, S. and Austin, J.C.
DOI: 10.1111/j.1399-0004.2008.01056.x
2009The management of depression during pregnancy: a report from the American Psychiatric Association and the American College of Obstetricians and Gynecologists.
Obstetrics and gynecology
Yonkers, K.A. and Wisner, K.L. and Stewart, D.E. and Oberlander, T.F. and Dell, D.L. and Stotland, N. and Ramin, S. and Chaudron, L. and Lockwood, C.
DOI: 10.1097/AOG.0b013e3181ba0632
2009Sustained neurobehavioral effects of exposure to ssri antidepressants during development: Molecular to clinical evidence
Clinical Pharmacology and Therapeutics
Oberlander, T.F. and Gingrich, J.A. and Ansorge, M.S.
DOI: 10.1038/clpt.2009.201
2009Caregiving behavior and interactions of prenatally depressed mothers (antidepressant-treated and non-antidepressant-treated) during newborn acute pain
Infant Mental Health Journal
Warnock, F.F. and Bakeman, R. and Shearer, K. and Misri, S. and Oberlander, T.
DOI: 10.1002/imhj.20220
2009Editorial: Optimizing neurodevelopmental outcomes in infants and children following prenatal SSRI exposure
Pediatric Health
Oberlander, T.F.
DOI: 10.2217/phe.09.56
2009Is it painful or not? Discriminant validity of the Behavioral Indicators of Infant Pain (BIIP) scale
Clinical Journal of Pain
Holsti, L. and Grunau, R.E. and Oberlander, T.F. and Osiovich, H.
DOI: 10.1097/AJP.0b013e318158c5e5
2008Effects of timing and duration of gestational exposure to serotonin reuptake inhibitor antidepressants: Population-based study
British Journal of Psychiatry
Oberlander, T.F. and Warburton, W. and Misri, S. and Aghajanian, J. and Hertzman, C.
DOI: 10.1192/bjp.bp.107.037101
2008Hypothalamic-pituitary-adrenal (HPA) axis function in 3-month old infants with prenatal selective serotonin reuptake inhibitor (SSRI) antidepressant exposure
Early Human Development
Oberlander, T.F. and Grunau, R. and Mayes, L. and Riggs, W. and Rurak, D. and Papsdorf, M. and Misri, S. and Weinberg, J.
DOI: 10.1016/j.earlhumdev.2008.06.008
2008Contingency learning and reactivity in preterm and full-term infants at 3 months
Infancy
Haley, D.W. and Grunau, R.E. and Oberlander, T.F. and Weinberg, J.
DOI: 10.1080/15250000802458682
2008Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
Epigenetics
Oberlander, T.F. and Weinberg, J. and Papsdorf, M. and Grunau, R. and Misri, S. and Devlin, A.M.
DOI: 10.4161/epi.3.2.6034
2008Major congenital malformations following prenatal exposure to serotonin reuptake inhibitors and benzodiazepines using population-based health data
Birth Defects Research Part B - Developmental and Reproductive Toxicology
Oberlander, T.F. and Warburton, W. and Misri, S. and Riggs, W. and Aghajanian, J. and Hertzman, C.
DOI: 10.1002/bdrb.20144
2008Infant serotonin transporter (SLC6A4) promoter genotype is associated with adverse neonatal outcomes after prenatal exposure to serotonin reuptake inhibitor medications
Molecular Psychiatry
Oberlander, T.F. and Bonaguro, R.J. and Misri, S. and Papsdorf, M. and Ross, C.J.D. and Simpson, E.M.
DOI: 10.1038/sj.mp.4002007
2008Pain management for children with a developmental disability in a primary care setting
Pain in Children: A Practical Guide for Primary Care
DOI: 10.1007/978-1-59745-476-6_4
2008Biobehavioural reactivity to pain in preterm infants: a marker of neuromotor development
Developmental Medicine & Child Neurology
Ruth E Grunau and Michael F Whitfield and Taryn Fay and Liisa Holsti and Timothy Oberlander and Marilynn L Rogers
DOI: 10.1111/j.1469-8749.2006.tb01298.x
02/2007In reply [5]
Archives of General Psychiatry
Oberlander, T.F. and Warburton, W. and Misri, S. and Aghajanian, J. and Hertzman, C.
DOI: 10.1001/archpsyc.64.7.867
2007Toward comprehensive treatment for postpartum depressed mothers and their infants
British Columbia Medical Journal
Lansky, P.S. and Oberlander, T.
2007Externalizing and attentional behaviors in children of depressed mothers treated with a selective serotonin reuptake inhibitor antidepressant during pregnancy
Archives of Pediatrics and Adolescent Medicine
Oberlander, T.F. and Reebye, P. and Misri, S. and Papsdorf, M. and Kim, J. and Grunau, R.E.
DOI: 10.1001/archpedi.161.1.22
2007Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: Characterization of gene duplication events
Clinical Pharmacology and Therapeutics
Gaedigk, A. and Ndjountché, L. and Divakaran, K. and Dianne Bradford, L. and Zineh, I. and Oberlander, T.F. and Brousseau, D.C. and McCarver, D.G. and Johnson, J.A. and Alander, S.W. and Riggs, K.W. and Leeder, J.S.
DOI: 10.1038/sj.clpt.6100033
2007Neonatal outcomes after prenatal exposure to selective serotonin reuptake inhibitor antidepressants and maternal depression using population-based linked health data
Archives of General Psychiatry
Oberlander, T.F. and Warburton, W. and Misri, S. and Aghajanian, J. and Hertzman, C.
DOI: 10.1001/archpsyc.63.8.898
2006Behavioral responses to pain are heightened after clustered care in preterm infants born between 30 and 32 weeks gestational age
Clinical Journal of Pain
Holsti, L. and Grunau, R.E. and Whifield, M.F. and Oberlander, T.F. and Lindh, V.
DOI: 10.1097/01.ajp.0000210921.10912.47
2006Internalizing behaviors in 4-year-old children exposed in utero to psychotropic medications
American Journal of Psychiatry
Misri, S. and Reebye, P. and Kendrick, K. and Carter, D. and Ryan, D. and Grunau, R.E. and Oberlander, T.F.
DOI: 10.1176/ajp.2006.163.6.1026
2006Stereoselective disposition of fluoxetine and norfluoxetine during pregnancy and breast-feeding
British Journal of Clinical Pharmacology
Kim, J. and Riggs, K.W. and Misri, S. and Kent, N. and Oberlander, T.F. and Grunau, R.E. and Fitzgerald, C. and Rurak, D.W.
DOI: 10.1111/j.1365-2125.2005.02538.x
2006A prospective controlled study of neurodevelopment in HIV-uninfected children exposed to combination antiretroviral drugs in pregnancy
Pediatrics
Alimenti, A. and Forbes, J.C. and Oberlander, T.F. and Money, D.M. and Grunau, R.E. and Papsdorf, M.P. and Maan, E. and Cole, L.J. and Burdge, D.R.
DOI: 10.1542/peds.2006-0525
2006Summary proceedings from the neonatal pain-control group
Pediatrics
DOI: 10.1542/peds.2005-0620C
2006Analgesia and local anesthesia during invasive procedures in the neonate
Clinical Therapeutics
DOI: 10.1016/j.clinthera.2005.06.018
2005Body movements: An important additional factor in discriminating pain from stress in preterm infants
Clinical Journal of Pain
Holsti, L. and Grunau, R.E. and Oberlander, T.F. and Whitfield, M.F. and Weinberg, J.
DOI: 10.1097/01.ajp.0000146163.30776.44
2005Neonatal procedural pain exposure predicts lower cortisol and behavioral reactivity in preterm infants in the NICU
Pain
Grunau, R.E. and Holsti, L. and Haley, D.W. and Oberlander, T. and Weinberg, J. and Solimano, A. and Whitfield, M.F. and Fitzgerald, C. and Yu, W.
DOI: 10.1016/j.pain.2004.10.020
2005Pain reactivity in 2-month-old infants after prenatal and postnatal selective serotonin reuptake inhibitor medication exposure
Pediatrics
Oberlander, T.F. and Grunau, R.E. and Fitzgerald, C. and Papsdorf, M. and Rurak, D. and Riggs, W.
DOI: 10.1542/peds.2004-0420
2005Analgesia and anesthesia for neonates: Study design and ethical issues
Clinical Therapeutics
DOI: 10.1016/j.clinthera.2005.06.021
2005Prior pain induces heightened motor responses during clustered care in preterm infants in the NICU
Early Human Development
Holsti, L. and Grunau, R.E. and Oberlander, T.F. and Whitfield, M.F.
DOI: 10.1016/j.earlhumdev.2004.08.002
2005Relation between prenatal maternal mood and anxiety and neonatal health
Canadian Journal of Psychiatry
Misri, S. and Oberlander, T.F. and Fairbrother, N. and Carter, D. and Ryan, D. and Kuan, A.J. and Reebye, P.
DOI: 10.1177/070674370404901006
2004Does Prone or Supine Position Influence Pain Responses in Preterm Infants at 32 Weeks Gestational Age?
Clinical Journal of Pain
Grunau, R.E. and Linhares, M.B.M. and Holsti, L. and Oberlander, T.F. and Whitfield, M.F.
DOI: 10.1097/00002508-200403000-00003
2004Specific newborn individualized developmental care and assessment program movements are associated with acute pain in preterm infants in the neonatal intensive care unit
Pediatrics
Holsti, L. and Grunau, R.E. and Oberlander, T.F. and Whitfield, M.F.
DOI: 10.1542/peds.114.1.65
2004Expression of Pain in Children with Autism
Clinical Journal of Pain
Nader, R. and Oberlander, T.F. and Chambers, C.T. and Craig, K.D.
DOI: 10.1097/00002508-200403000-00005
2004Pharmacologic factors associated with transient neonatal symptoms following prenatal psychotropic medication exposure
Journal of Clinical Psychiatry
Oberlander, T.F. and Misri, S. and Fitzgerald, C.E. and Kostaras, X. and Rurak, D. and Riggs, W.
DOI: 10.4088/JCP.v65n0214
2004Are there developmentally distinct motor indicators of pain in preterm infants?
Early Human Development
Morison, S.J. and Holsti, L. and Grunau, R.E. and Whitfield, M.F. and Oberlander, T.F. and Chan, H.W.P. and Williams, L.
DOI: 10.1016/S0378-3782(03)00044-6
2003Does parenchymal brain injury affect biobehavioral pain responses in very low birth weight infants at 32 weeks' postconceptional age?
Pediatrics
Oberlander, T.F. and Grunau, R.E. and Fitzgerald, C. and Whitfield, M.F.
DOI: 10.1542/peds.110.3.570
2002Prevention in adulthood: Forging a doctor-patient partnership
Primary Care - Clinics in Office Practice
Oberlander, T. and Saul, J.Philip
DOI: 10.1016/S0095-4543(02)00018-0
2002Prolonged prenatal psychotropic medication exposure alters neonatal acute pain response
Pediatric Research
Oberlander, T.F. and Grunau, R.E. and Fitzgerald, C. and Ellwood, A.-L. and Misri, S. and Rurak, D. and Riggs, K.W.
DOI: 10.1203/00006450-200204000-00008
2002Methodological considerations for the use of heart rate variability as a measure of pain reactivity in vulnerable infants
Clinics in Perinatology
Oberlander, T. and Saul, J.Philip
DOI: 10.1016/S0095-5108(02)00013-1
2002Relations between behavioral and cardiac autonomic reactivity to acute pain in preterm neonates
Clinical Journal of Pain
Morison, S.J. and Grunau, R.E. and Oberlander, T.F. and Whitfield, M.F.
DOI: 10.1097/00002508-200112000-00010
2001Pain reactivity in former extremely low birth weight infants at corrected age 8 months compared with term born controls
Infant Behavior and Development
Eckstein Grunau, R. and Oberlander, T.F. and Whitfield, M.F. and Fitzgerald, C. and Morison, S.J. and Philip Saul, J.
DOI: 10.1016/S0163-6383(01)00065-0
2001Demographic and therapeutic determinants of pain reactivity in very low birth weight neonates at 32 weeks' postconceptional age
Pediatrics
Grunau, R.E. and Oberlander, T.F. and Whitfield, M.F. and Fitzgerald, C. and Lee, S.K.
DOI: 10.1542/peds.107.1.105
2001Pain Assessment and Management in Infants and Young Children with Developmental Disabilities
Infants and Young Children
Oberlander, T.F.
DOI: 10.1097/00001163-200114020-00006
2001Beliefs about pain among professionals working with children with significant neurologic impairment
Developmental Medicine and Child Neurology
Oberlander, T.F. and O'Donnell, M.E.
DOI: 10.1017/S0012162201230254
2001Biobehavioral Pain Responses in Former Extremely Low Birth Weight Infants at Four Months' Corrected Age
Pediatrics
Tim F. Oberlander and Ruth Eckstein Grunau and Michael F. Whitfield and Colleen Fitzgerald and Sandy Pitfield and J. Philip Saul
DOI: 10.1542/peds.105.1.e6
01/2000Prenatal and Breast Milk Morphine Exposure Following Maternal Intrathecal Morphine Treatment
Journal of Human Lactation
Oberlander, T.F. and Robeson, P. and Ward, V. and Huckin, R.S. and Kamani, A. and Harpur, A. and McDonald, W.
DOI: 10.1177/089033440001600210
2000Evaluating treatment outcome in an interdisciplinary pediatric pain service
Pain Research and Management
Bennett, S.M. and Chambers, C.T. and Bellows, D. and Court, C.A. and Huntsman, E. and Montgomery, C. and Oberlander, T.F. and Sheriff, M. and Siden, H.
DOI: 10.1155/2000/767058
2000The Developmental Character of Cardiac Autonomic Responses to an Acute Noxious Event in 4- and 8-Month-Old Healthy Infants
Pediatric Research
Tim F Oberlander and Ruth Eckstein Grunau and Sandy Pitfield and Michael F Whitfield and J Philip Saul
DOI: 10.1203/00006450-199904010-00011
04/1999Biobehavioral responses to acute pain in adolescents with a significant neurologic impairment
Clinical Journal of Pain
Oberlander, T.F. and Gilbert, C.A. and Chambers, C.T. and O'Donnell, M.E. and Craig, K.D.
DOI: 10.1097/00002508-199909000-00007
1999Pain in children with significant neurological impairment
Journal of Developmental and Behavioral Pediatrics
Oberlander, T.F. and O'Donnell, M.E. and Montgomery, C.J.
DOI: 10.1097/00004703-199908000-00006
1999The developmental character of cardiac autonomic responses to an acute noxious event in 4-and 8-month-old healthy infants
Pediatric Research
Oberlander, T.F. and Grunau, R.E. and Pitfield, S. and Whitfield, M.F. and Saul, J.P.
1999Pain management of junctional epidermolysis bullosa in an 11-year-old boy
Pediatric Dermatology
Chiu, Y.-K. and Prendiville, J.S. and Bennett, S.M. and Montgomery, C.J. and Oberlander, T.F.
DOI: 10.1046/j.1525-1470.1999.00120.x
1999Bedside application of the neonatal facial coding system in pain assessment of premature neonates
Pain
Grunau, R.E. and Oberlander, T. and Holsti, L. and Whitfield, M.F.
DOI: 10.1016/S0304-3959(98)00046-3
1998Cardiac Autonomic and Behavioral Responses to Acute Pain in 4 Month Old Infants † 80
Pediatric Research
DOI: 10.1203/00006450-199704001-00101
04/1997Developmental character and long-term consequences of pain in infants and children
Child and Adolescent Psychiatric Clinics of North America
Anand, K.S. and Grunau, R.E. and Oberlander, T.F.
1997Erratum: Halothane and cardiac autonomic control in infants: Assessment with quantitative respiratory sinus arrhythmia (Pediatric Research (1996) 40 (710-717))
Pediatric Research
Oberlander, T.F.
1997Halothane and cardiac autonomic control in infants: Assessment with quantitative respiratory sinus arrhythmia
Pediatric Research
Oberlander, T.F. and Berde, C.B. and Saul, J.P.
DOI: 10.1203/00006450-199611000-00010
1996Time and frequency domain methods for heart rate variability analysis: A methodological comparison
Psychophysiology
LITVACK, D.A. and OBERLANDER, T.F. and CARNEY, L.H. and SAUL, J.P.
DOI: 10.1111/j.1469-8986.1995.tb02101.x
1995Infants tolerate spinal anesthesia with minimal overall autonomic changes: Analysis of heart rate variability in former premature infants undergoing hernia repair
Anesthesia and Analgesia
Oberlander, T.F. and Berde, C.B. and Lam, K.H. and Rappaport, L.A. and Saul, J.P.
DOI: 10.1097/00000539-199501000-00005
1995EFFECTS OF INTRA-ORAL SUCROSE ON CRYING, MOUTHING AND HAND-MOUTH CONTACT IN NEWBORN AND SIX-WEEK-OLD INFANTS
Developmental Medicine & Child Neurology
Barr, R.G. and Quek, V.S.H. and Cousineau, D. and Oberlander, T.F. and Brian, J.A. and Young, S.N.
DOI: 10.1111/j.1469-8749.1994.tb11898.x
1994Recurrent abdominal pain: evaluation and management
International Seminars in Paediatric Gastroenterology and Nutrition
1994Recurrent abdominal pain during childhood.
Pediatrics in review / American Academy of Pediatrics
Oberlander, T.F. and Rappaport, L.A.
DOI: 10.1542/pir.14-8-313
1993Advice Seeking and Appropriate Use of a Pediatric Emergency Department
American Journal of Diseases of Children
Oberlander, T.F. and Pless, I.B. and Dougherty, G.E.
DOI: 10.1001/archpedi.1993.02160320065021
1993Short-term effects of feed composition on sleeping and crying in newborns
Pediatrics
Oberlander, T.F. and Barr, R.G. and Young, S.N. and Brian, J.A.
1992 - Research
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Current Projects
My research extends from studies of child behaviour at the individual to population levels that seeks to understand how in utero exposure to maternal mood and selective serotonin reuptake inhibitor (SSRI) antidepressants sets pathways for both developmental risk and resiliency during early childhood. My work provides strong evidence that both influences have an impact on stress regulation and mood in childhood, possibly reflecting early changes in central serotonin (5HT) levels.
Increasingly my work is showing that the developing brain has a remarkable capacity for change, such that even in the face of adversity, some children do very well. The goal of my work is to figure out how and why this happens, and use these findings to identify opportunities for interventions that reduce risk. Emerging findings are beginning to point to ways that could possibly assist clinicians and families in understanding critical issues that influence a child’s emotional well-being and academic success later in school. As Project Lead for CFRI’s 3T MR Imaging facility I have the opportunity to advance studies of early brain development using advance imaging technology.
I have three main areas of research:
Developmental effects of prenatal psychotropic medication exposure – fetal, neonatal, infant and childhood outcomes: This research focuses on studies of the developmental impact of prenatal exposure to psychotropic medications (i.e. selective serotonin reuptake inhibitor [SSRI] antidepressants) and depressed maternal mood that extends from fetal periods to early adolescence. Biobehavioural, pharmacologic and genetic factors that moderate fetal exposure are studied. Outcomes of particular interest are pain/stress reactivity (neuroendocrine, heart variability), cognitive function (executive functions), attention threat bias, and measures of arousal and emotional regulation. This work also includes examination of the role of key genetic (i.e. SLC6A4) variations and epigenetic (i.e. methylation) factors that may also contribute to altered early serotonin levels.
Pharmacoepidemiology and Child Development: Since 2004 we have used population level health data linking antenatal maternal prescription records with birth/neonatal health records to distinguish the impact of maternal mood from in utero SSRI exposure. We have reported novel findings indicting that the effects of gestational maternal SSRI use differ from those of maternal mental illness and that neonatal outcomes vary with the timing and duration of prenatal SSRI exposure. Recently, we have started examining developmental and behavioural outcomes (learning, mood and autism spectrum disorder risk, ASD) related to in utero SSRI exposure, socioeconomic conditions and maternal mental health.
Pain and children with developmental disabilities: This research seeks to understand pain in children with developmental disabilities. The current focus of this work is to improve pain assessment management among this population of children.
Research Methodology
Fetal, neonatal and child behavioural state regulation
Non invasive stress measures (cardiac autonomic (RSA, PEP), salivary alpha-amylase & cortisol)
Integration of genetic and epigenetic factors to study interactions reflecting the impact of early experience
Population-based linked child health dataGrantsCIHR Operating Grant - Project: "Attention bias and executive functions in 9-14 year olds following prenatal antidepressant exposure" (2014-2019)
CIHR Operating Grant - Project: "Developmental origins of autism: A population level linked data study of prenatal antidepressant medication exposure" (2014-2017)
CIHR Operating Grant - Project: "Early child behavior: Relations to early brain development and maternal mood" (2012-2017)
Honours & AwardsEarly Career UBC Scholar, The Peter Wall Institute for Advanced Studies, UBC (2003-2004)
Human Early Learning Partnership, Senior Scholar Award (2002-2005)
R. Howard Webster Professor in Early Childhood Development (2004-present)
Research Group MembersUrsula Brain, Research Manager, Healthy Starts Program
Dawna Brown, Research Assistant
Kayleigh Campbell
Efrat Czerniak, Volunteer
Sarah Hutchison, Sunny Hill Child Development and Rehabilitation Research Manager
Jessica Luu, Research Assistant Tech 2
Mandeep Mahal, Developmental Pediatrics Subspecialty Resident
Bianca Matthews, Summer Student - Research Assistant
Amanda Nitschke, Doctoral Student
Colleen Pawliuk, Research Librarian
Leora Pearl-Dowler, Summer student
Katie Rintoul, Research Assistant
Jane Shen, researcher
Marie-Noelle Wharton Cancio, Research Coordinator
Enav Zusman
State-of-the-art scans show a connection between exposure to anti-depressant before birth and changes in newborn’s brain activity
Dr. Tim Oberlander and his colleagues have used state-of-the-art MRI scans to study the effects of SSRI anti-depressants on the developing brain. Their work could eventually provide valuable information about the long-term consequences of taking these drugs during pregnancy and contribute to new approaches for managing depression that give both mothers and babies the best possible chance for a long-term health.
