- Overview
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My research interests range from studies involving paediatric hip, lower limbs, feet, trauma and bone tumours. I am specifically interested in advancing research around paediatric bone health and mobility. In addition to looking at the clinical outcomes, I am also interested in looking at the outcomes reported directly by the patients or caregivers of patients, specifically their quality of life. By studying these outcomes, I am aiming to look at the effectiveness of treatments I use in clinic and to explore ways to improve the quality of life of my patients. I also collaborate with biomechanical engineers to generate computerised models of the hip in order to imitate different deformities around the hip joint.
- Publications
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Fully Automated Analysis of the Anatomic and Mechanical Axes From Pediatric Standing Lower Limb Radiographs Using Convolutional Neural Networks
Journal of Pediatric Orthopaedics
DOI: 10.1097/BPO.0000000000002611
2024Risk Factor Analysis for Growth Arrest in Paediatric Physeal Fractures—A Prospective Study
Journal of Clinical Medicine
DOI: 10.3390/jcm13102946
2024Morquio B disease: a case report
Frontiers in Pediatrics
DOI: 10.3389/fped.2024.1285414
2024Slipped capital femoral epiphysis: emphasis on early recognition and potential pitfalls
Skeletal Radiology
DOI: 10.1007/s00256-024-04798-x
2024Early Investigation and Bracing in DDH Impacts Maternal Wellbeing and Breastfeeding
Journal of Pediatric Orthopaedics
Hoffer, A. and Chhina, H. and Mulpuri, K. and Cooper, A.P.
DOI: 10.1097/BPO.0000000000002274
2023Inter-and Intra-rater Reliability of the Checketts’ Grading System for Pin-site Infections across All Skin Colours
Strategies in Trauma and Limb Reconstruction
DOI: 10.5005/jp-journals-10080-1581
2023Multimodal Analgesia for Paediatric Patients Undergoing Lower Limb Reconstruction with External Fixators: A Prospective Case Series of Post-operative Pain and Functional Goals
Strategies in Trauma and Limb Reconstruction
DOI: 10.5005/jp-journals-10080-1601
2023Danish Linguistic Validation and Cultural Adaptation of the LIMB-Q Kids
Children
DOI: 10.3390/children10071107
2023Establishing content validity of LIMB-Q Kids: a new patient-reported outcome measure for lower limb deformities
Quality of Life Research
Harpreet Chhina and Anne Klassen and David Bade and Jacek Kopec and Anthony Cooper
DOI: 10.1007/s11136-022-03140-z
09/2022LIMB-Q Kids—German Translation and Cultural Adaptation
Children
Bjoern Vogt and Jana Fresen and Georg Gosheger and Harpreet Chhina and Carolin Sophie Brune and Gregor Toporowski and Adrien Frommer and Andrea Laufer and Anthony Cooper and Robert Roedl and Jan Duedal Rölfing
DOI: 10.3390/children9091405
09/2022Efficacy and Safety of "sleeper Plate" in Temporary Hemiepiphysiodesis and the Observation of "tethering"
Journal of Pediatric Orthopaedics
Gerges, M. and Messner, J. and Lim, B. and Chhina, H. and Cooper, A.
DOI: 10.1097/BPO.0000000000002184
2022Late Ankle Reconstruction in a Child with Remote Traumatic Medial Malleolus Loss: Clinical and Radiographic Outcomes
Strategies in Trauma and Limb Reconstruction
Ponton, E. and Bakkai, A. and Courtemanche, D.J. and Cooper, A.P.
DOI: 10.5005/jp-journals-10080-1552
2022Human complete NFAT1 deficiency causes a triad of joint contractures, osteochondromas, and B-cell malignancy
Blood
Sharma, M. and Fu, M.P. and Lu, H.Y. and Sharma, A.A. and Modi, B.P. and Michalski, C. and Lin, S. and Dalmann, J. and Salman, A. and Del Bel, K.L. and Waqas, M. and Terry, J. and Setiadi, A. and Lavoie, P.M. and Wasserman, W.W. and Mwenifumbo, J. and Kobor, M.S. and Lee, A.F. and Kuchenbauer, F. and Lehman, A. and Cheng, S. and Cooper, A. and Patel, M.S. and Turvey, S.E.
DOI: 10.1182/blood.2022015674
2022Human germline biallelic complete NFAT1 deficiency causes the triad of progressive joint contractures, osteochondromas, and susceptibility to B cell malignancy
medRxiv
Sharma, M. and Fu, M.P. and Lu, H.Y. and Sharma, A.A. and Modi, B.P. and Michalski, C. and Lin, S. and Dalmann, J. and Salman, A. and Del Bel, K.L. and Waqas, M. and Terry, J. and Setiadi, A. and Lavoie, P.M. and Wasserman, W.W. and Mwenifumbo, J. and Kobor, M.S. and Lee, A.F. and Lehman, A. and Cheng, S. and Cooper, A. and Patel, M.S. and Turvey, S.E.
DOI: 10.1101/2022.01.30.22269378
2022Paediatric elbow fractures and public play spaces: adherence to standards for children’s playground equipment and surfacing
BMJ Paediatrics Open
Jennifer Smith and Harpreet Chhina and Pardeep Sidhu and Mariana Brussoni and Ian Pike and Anthony Cooper
DOI: 10.1136/bmjpo-2021-001125
11/2021Clinical outcomes in pediatric tibial lengthening and deformity correction: a comparison of the Taylor Spatial Frame with the Orthex Hexapod System.
Journal of children's orthopaedics
DOI: 10.1302/1863-2548.15.200165
PubMed: 34040657
04/2021What matters to children with lower limb deformities: an international qualitative study guiding the development of a new patient-reported outcome measure.
Journal of patient-reported outcomes
DOI: 10.1186/s41687-021-00299-w
PubMed: 33792793
04/2021Survey of the impact of COVID-19 on pediatric orthopaedic surgeons globally
Journal of Pediatric Orthopaedics
Gibbard, M. and Ponton, E. and Sidhu, B.V. and Farrell, S. and Bone, J.N. and Wu, L.A. and Schaeffer, E. and Cooper, A. and Aroojis, A. and Mulpuri, K.
DOI: 10.1097/BPO.0000000000001887
2021Inter-rater and Intra-rater Reliability in the Radiographic Diagnosis of Growth Arrest in Paediatric Physeal Fractures
Indian Journal of Orthopaedics
Banting, N. and Schaeffer, E.K. and Bone, J. and Habib, E. and Hooper, N. and Reilly, C.W. and Cooper, A. and Mulpuri, K.
DOI: 10.1007/s43465-020-00327-9
2021Correction of genu recurvatum deformity using a hexapod frame: A case series and review of the literature
Strategies in Trauma and Limb Reconstruction
Johnson, L. and McCammon, J. and Cooper, A.
DOI: 10.5005/JP-JOURNALS-10080-1528
2021Is the modified Gartland classification system important in deciding the need for operative management of supracondylar humerus fractures?
Journal of children's orthopaedics
Teo TL and Schaeffer EK and Habib E and El-Hawary R and Larouche P and Shore B and Aarvold A and Carsen S and Reilly C and Mulpuri K
DOI: 10.1302/1863-2548.14.200093
PubMed: 33343744
12/2020Methodological Challenges in Investigating Supracondylar Fractures of the Humerus From a Child's Viewpoint: Evolution of Study Protocol.
JMIR research protocols
DOI: 10.2196/21816
PubMed: 33136061
11/20203-D Ultrasound Imaging Reliability of Measuring Dysplasia Metrics in Infants.
Ultrasound in medicine & biology
Quader N and Hodgson AJ and Mulpuri K and Cooper A and Garbi R
DOI: 10.1016/j.ultrasmedbio.2020.08.008
PubMed: 33239155
10/2020Dynamic deformation of the femoral head occurs on weightbearing in Legg-Calves-Perthes disease
Bone & Joint Open
Alexander Aarvold and Ryan Lohre and Harpreet Chhina and Kishore Mulpuri and Anthony Cooper
DOI: 10.1302/2046-3758.17.bjo-2020-0030.r1
07/2020Dynamic deformation of the femoral head occurs on weightbearing in Legg-Calves-Perthes disease: a translational pilot study.
Bone & joint open
Aarvold A and Lohre R and Chhina H and Mulpuri K and Cooper A
DOI: 10.1302/2633-1462.17.bjo-2020-0030.r1
PubMed: 33215126
07/2020Methodological Challenges in Investigating Supracondylar Fractures of the Humerus From a Child’s Viewpoint: Evolution of Study Protocol (Preprint)
Brittany Tara Lim and Harpreet Chhina and Ian Pike and Mariana Brussoni and Anthony Cooper
DOI: 10.2196/preprints.21816
06/2020Modernization of bone age assessment: comparing the accuracy and reliability of an artificial intelligence algorithm and shorthand bone age to Greulich and Pyle
Skeletal Radiology
Gerges, M. and Eng, H. and Chhina, H. and Cooper, A.
DOI: 10.1007/s00256-020-03429-5
2020What matters to children with lower limb deformities; an international qualitative study informing the development of LIMB-Q Kids
Quality of Life Research
10/2019Assessing the reliability of the modified gartland classification system for extension-type supracondylar humerus fractures
Journal of Children's Orthopaedics
Teo, T.L. and Schaeffer, E.K. and Habib, E. and Cherukupalli, A. and Cooper, A.P. and Aroojis, A. and Sankar, W.N. and Upasani, V.V. and Carsen, S. and Mulpuri, K. and Reilly, C.
DOI: 10.1302/1863-2548.13.190005
2019Automated dynamic 3D ultrasound assessment of developmental dysplasia of the infant Hip
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
DOI: 10.1007/978-3-030-11166-3_12
2019Support, information, and integration of genetics for children with congenital lower limb deficiencies in British Columbia, Canada
Paediatrics and Child Health (Canada)
Campbell, T. and Chen, C.-Y. and Chhina, H. and Chahal, R. and Cooper, A. and Elliott, A.M.
DOI: 10.1093/pch/pxz001
2019International multiphase mixed methods study protocol to develop a patient-reported outcome instrument for children and adolescents with lower limb deformities
BMJ Open
Chhina, H. and Klassen, A. and Kopec, J.A. and Oliffe, J. and Cooper, A.
DOI: 10.1136/bmjopen-2018-027079
2019Coxa Vara
The Pediatric and Adolescent Hip: Essentials and Evidence
DOI: 10.1007/978-3-030-12003-0_7
2019Inter- and Intra-observer reliability of the pixel value ratio, Ru Li's and Donnan's classifications of regenerate quality in pediatric limb lengthening
Journal of Limb Lengthening & Reconstruction
DOI: 10.4103/jllr.jllr_11_17
2018Southwick angle measurements and SCFE slip severity classifications are affected by frog-lateral positioning
Skeletal Radiology
Jones, C.E. and Cooper, A.P. and Doucette, J. and Buchan, L.L. and Wilson, D.R. and Mulpuri, K. and d?Entremont, A.G.
DOI: 10.1007/s00256-017-2761-z
2018Real time RNN based 3D ultrasound scan adequacy for developmental dysplasia of the hip
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
DOI: 10.1007/978-3-030-00928-1_42
2018Do Immediate Postoperative Radiographs Change Patient Management after Fracture Fixation? A Systematic Review
Journal of Orthopaedic Trauma
DOI: 10.1097/BOT.0000000000001152
2018Qualitative Insights to Health Related Quality Of Life among US and Canadian based Children with Lower Limb Deformities
Quality of Life Research
10/2017Comparison of self-reports and parent proxy-reports on the quality of life and function of children with lower limb deformities
Quality of Life Research
10/2017Quality of life of children with lower limb deformities: A systematic review of patient-reported outcomes and development of a preliminary conceptual framework
Journal of Limb Lengthening & Reconstruction
Anthony Cooper and Harpreet Chhina and Anne Klassen and Jacek Kopec and Sujin Park and Cadi Fortes
DOI: 10.4103/jllr.jllr_33_16
2017A 3D femoral head coverage metric for enhanced reliability in diagnosing hip dysplasia
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
DOI: 10.1007/978-3-319-66182-7_12
2017Automatic Near Real-Time Evaluation of 3D Ultrasound Scan Adequacy for Developmental Dysplasia of the Hip
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
DOI: 10.1007/978-3-319-67543-5_12
2017Relationships between Severity of Deformity and Impingement in Slipped Capital Femoral Epiphysis
Journal of Pediatric Orthopaedics
Jones, C.E. and Cooper, A.P. and Doucette, J. and Buchan, L.L. and Wilson, D.R. and Mulpuri, K. and D'Entremont, A.G.
DOI: 10.1097/BPO.0000000000000641
2017Automatic evaluation of scan adequacy and dysplasia metrics in 2D ultrasound images of the neonatal hip
The Bone & Joint Journal
12/2016Evidence-Based Treatment for Congenital Femoral Deficiency
Paediatric Orthopaedics
DOI: 10.1007/978-3-319-41142-2_7
11/2016Development of a patient-reported outcome instrument to measure quality of life of children with lower limb deformities: preliminary results
Quality of Life Research
10/2016Standing weight bearing MRI for evaluation of Legg-Calvé-Perthes disease: a pilot study
Journal of Bone and Joint Surgery
09/2016A Reliable Automatic 2D Measurement for Developmental Dysplasia of the Hip
Journal of Bone and Joint Surgery
04/2016Arthroscopic treatment of femoroacetabular impingement following slipped capital femoral epiphysis
Bone and Joint Journal
Basheer, S.Z. and Cooper, A.P. and Maheshwari, R. and Balakumar, B. and Madan, S.
DOI: 10.1302/0301-620X.98B1.35831
2016Management of displaced supracondylar fractures of the humerus using lateral versus cross k wires: a prospective randomised trial
Journal of Bone and Joint Surgery
2016Towards reliable automatic characterization of neonatal hip dysplasia from 3D ultrasound images
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
DOI: 10.1007/978-3-319-46720-7_70
2016Lower limb deficiency syndromes
Orthopaedics and Trauma
Cooper, A. and Fernandes, J.A.
DOI: 10.1016/j.mporth.2016.09.007
2016What Clinimetric Evidence Exists for Using Hip-specific Patient-reported Outcome Measures in Pediatric Hip Impingement?
Clinical Orthopaedics and Related Research
d?Entremont, A.G. and Cooper, A.P. and Johari, A. and Mulpuri, K.
DOI: 10.1007/s11999-014-4027-6
2015The Multiplier Method for Predicting Limb Length Discrepancy in Patients with Vascular Anomalies in the Lower Limb
Journal of Limb Lengthening and Reconstruction
2015The foot and ankle
Postgraduate Paediatric Orthopaedics
DOI: 10.1007/9781107415065
2014The contralateral foot in children with unilateral clubfoot, is the unaffected side normal?
Gait and Posture
Cooper, A. and Chhina, H. and Howren, A. and Alvarez, C.
DOI: 10.1016/j.gaitpost.2014.05.004
2014The oblique plane deformity in slipped capital femoral epiphysis
Journal of Children's Orthopaedics
Cooper, A.P. and Salih, S. and Geddis, C. and Foster, P. and Fernandes, J.A. and Madan, S.S.
DOI: 10.1007/s11832-014-0559-2
2014Foot disorders in childhood
Surgery (United Kingdom)
Cooper, A. and Jones, S.
DOI: 10.1016/j.mpsur.2013.11.004
2014Evidence-based management of developmental dysplasia of the hip
Orthopedic Clinics of North America
Cooper, A.P. and Doddabasappa, S.N. and Mulpuri, K.
DOI: 10.1016/j.ocl.2014.03.005
2014A novel method for assessing postoperative femoral head reduction in developmental dysplasia of the hip
Journal of Children's Orthopaedics
Cooper, A. and Evans, O. and Ali, F. and Flowers, M.
DOI: 10.1007/s11832-014-0600-5
2014Rotator cuff tears
Surgery (Oxford)
Anthony Cooper and Amjid Ali
DOI: 10.1016/j.mpsur.2013.01.017
04/2013The treatment of severe slipped capital femoral epiphysis via the Ganz surgical dislocation and anatomical reduction: a prospective study.
The bone & joint journal
DOI: 10.1302/0301-620x.95b3.30113
PubMed: 23450032
03/2013The treatment of severe slipped capital femoral epiphysis via the Ganz surgical dislocation and anatomical reduction: A prospective study
Journal of Bone and Joint Surgery - Series B
Madan, S.S. and Cooper, A.P. and Davies, A.G. and Fernandes, J.A.
DOI: 10.1302/0301-620X.95B3
2013Outcomes of hip arthroscopy. A prospective analysis and comparison between patients under 25 and over 25 years of age
British Journal of Sports Medicine
Cooper, A.P. and Basheer, S.Z. and Maheshwari, R. and Regan, L. and Madan, S.S.
DOI: 10.1136/bjsports-2012-091028
2013Redislocation and the computerised tomography evaluation of developmental dysplasia of the hip
Journal of Bone and Joint Surgery
2012Service Evaluation of Work Performed by Non-Consultant-Grade Doctors at Night
The Bulletin of the Royal College of Surgeons of England
K Hassan and L McGrath and K Thomas and L Henderson and S Thangiaraj and A Kocheta and B Wilson and S Royston and A Cooper
DOI: 10.1308/147363510x514154
07/2010Routine intra-operative microbiological samples in direct exchanges of total hip replacements. A retrospective analysis of 100 consecutive cases with minimum 1 year follow up
Journal of Bone and Joint Surgery
2010Voriconazole-impregnated beads in the treatment of candidal prosthetic joint infection
Clinical Microbiology and Infection
04/2009A rare example of pseudodislocation of the acromioclavicular joint in a 12 year old boy
Journal of Orthopaedics
2008Quantifying Dynamic Assessment of Developmental Dysplasia of the Hip
Olivia Paserin and Niamul Quader and Kishore Mulpuri and Anthony Cooper and Emily Schaeffer and Antony J. Hodgson and Rafeef Abugharbieh
DOI: 10.29007/zh41 - Research
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Preventative Multimodal Analgesia for Children Undergoing Lower Limb Reconstruction with External Fixators: A Prospective Study of Postoperative Pain
Objective: To assess the peri-operative analgesia regimen that has been previously developed for children undergoing limb reconstruction surgery at BC Children’s Hospital, during the acute and long-term post-operative recovery phase. This study is being conducted in collaboration with the Department of Anesthesiology, Pharmacology & Therapeutics.Multicentre Pin Site Infection Study
Objective: To measure and document pin site infection rate and pin site care across Canada, US and UK through a multi-centre pin site infection database. This study involving ten surgeons (BCCH being the primary site) across various sites will provide important information for limb lengthening and reconstruction services across the world, as well as parents/primary caregivers of children in external fixation devices (EFDs). By identifying the factors contributing to pin site infections, this study will take another step towards improving clinical care for children in EFDs.Health-related Quality of Life in Children with Lower Limb Deficiency
Objectives: a) To develop and validate a patient-reported quality of life tool for children with lower limb deficiency; b) To establish the baseline health-related quality of life in these children using the newly developed tool; c) To investigate the quality of life of caregivers of children with lower limb deficiency.GrantsTitle
Development of a Patient Reported Quality of Life Questionnaire for Children with Lower Limb Deformities Funding Agency
Canadian Orthopaedic Research Legacy (CORL) Year
2017-2019
Title
Evaluating the Accuracy of the Paley Multiplier Method for Predicting Limb Length Discrepancy in Populations with Vascular Anomalies Funding Agency
UBC Plastic Surgery Academic Grant Year
2016-2017
Title
Paediatric Limb Reconstruction Funding Agency
CFRI Investigator Grant Award Program (IGAP) Year
2016-2021
Honours & AwardsGetty Plate for best academic project 2011 (Runner up)
Investigator Grant Award, CFRI, 2016
Limb Lengthening and Reconstruction Society Traveling Fellowship, 2016
Research Group MembersTaqdir Ali, Postdoctoral Fellow
Yumi Chang, Admin Coordinator, Academic Coordinator
Harpreet Chhina, Research Associate
Sophie Davidson, Research Assistant
Emily Dunnion
Josh Dyce, Research Assistant
Tara Gholamian, Research Assistant
Mina Han, Research Assistant
Gael Hernandez Palmer, Co-op Student
Brittany Lim, Research Asisstant
Aidan Loh, Research Assistant
Kaylee McGeough, Research Assistant
Maitri Panchal
Ryanne Uy, Research Assistant
Congratulations CIHR Fall 2022 Project Grant recipients
Congratulations to the BC Children’s Hospital Research Institute (BCCHR) and Women’s Health Research Institute (WHRI) investigators and their teams who were awarded $8 million in funding through the Canadian Institutes of Health Research (CIHR) Fall 2022 Project Grant competition.
