BCCHR Researchers Find a Researcher

Alexander C. Ferguson

FRCPC, MBChB

Investigator Emeritus, BC Children's Hospital

Asthma and allergy involves interaction of the individual person with their environment and involves both genetic and environmental factors. Modifying the environment of those who are at risk of developing allergy and asthma may be important in prevention or modifying the severity of disease. Understanding the underlying changes in the tissues which lead to symptoms and assessing the beneficial, and possible adverse, effects of therapy will lead to optimal treatment and the best outcome for children affected.

Academic Affiliations

Professor Emeritus/a, Division of Allergy, Department of Pediatrics, Faculty of Medicine, University of British Columbia
Research Theme: No Theme Affiliation

Contact Information

Location

4500 Oak St, Vancouver, BC, Canada, V6H 3N1

(604) 875-2118

aferguson@cw.bc.ca

Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation?

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Silverwood RJ and Rutter CE and Mitchell EA and Asher MI and Garcia-Marcos L and Strachan DP and Pearce N and ISAAC Phase Three Study Group

DOI: 10.1111/cea.13325 PubMed: 30508327

01 / 2019

Are Environmental Factors for Atopic EczemainISAAC Phase Three due to ReverseCausation?

The Journal of investigative dermatology

Rutter CE and Silverwood RJ and Williams HC and Ellwood P and Asher I and Garcia-Marcos L and Strachan DP and Pearce N and Langan SM and ISAAC Phase Three Study Group

DOI: 10.1016/j.jid.2018.08.035 PubMed: 30521836

12 / 2018

Association between Frequency of Consumption of Fruit, Vegetables, Nuts and Pulses and BMI: Analyses of the International Study of Asthma and Allergies in Childhood (ISAAC).

Nutrients

Wall CR and Stewart AW and Hancox RJ and Murphy R and Braithwaite I and Beasley R and Mitchell EA and ISAAC Phase Three Study Group

DOI: 10.3390/nu10030316 PubMed: 29518923

03 / 2018

Body mass index and vigorous physical activity in children and adolescents: an international cross-sectional study

Acta Paediatrica

DOI: 10.1111/apa.13903

08 / 2017

Maternal post-natal tobacco use and current parental tobacco use is associated with higher body mass index in children and adolescents: an international cross-sectional study

BMC Pediatrics

DOI: 10.1186/s12887-015-0538-x

12 / 2015

Atopic dermatitis in a high-risk cohort: Natural history, associated allergic outcomes, and risk factors

Annals of Allergy, Asthma and Immunology

Carlsten, C. and Dimich-Ward, H. and Ferguson, A. and Watson, W. and Rousseau, R. and Dybuncio, A. and Becker, A. and Chan-Yeung, M.

DOI: 10.1016/j.anai.2012.10.005

Association between endotoxin and mite allergen exposure with asthma and specific sensitization at age 7 in high-risk children

Pediatric Allergy and Immunology

Carlsten, C. and Ferguson, A. and Dimich-Ward, H. and Chan, H. and Dybuncio, A. and Rousseau, R. and Becker, A. and Chan-Yeung, M.

DOI: 10.1111/j.1399-3038.2010.01123.x

Airway hyperresponsiveness to methacholine in 7-year-old children: Sensitivity and specificity for pediatric allergist-diagnosed asthma

Pediatric Pulmonology

Carlsten, C. and Dimich-Ward, H. and Ferguson, A. and Becker, A. and Dybuncio, A. and Chan-Yeung, M.

DOI: 10.1002/ppul.21347

Disparate geographic prevalences of asthma, allergic rhinoconjunctivitis and atopic eczema among adolescents in five Canadian cities

Pediatric Allergy and Immunology

Wang, H.-Y. and Pizzichini, M.M.M. and Becker, A.B. and Duncan, J.M. and Ferguson, A.C. and Greene, J.M. and Rennie, D.C. and Senthilselvan, A. and Taylor, B.W. and Sears, M.R.

DOI: 10.1111/j.1399-3038.2010.01064.x

Indoor allergen exposure, sensitization, and development of asthma in a high-risk birth cohort

Pediatric Allergy and Immunology

Carlsten, C. and Dimich-Ward, H. and Becker, A.B. and Ferguson, A. and Chan, H.W. and Dybuncio, A. and Chan-Yeung, M.

DOI: 10.1111/j.1399-3038.2010.01021.x

Elevated cord blood IgE is associated with recurrent wheeze and atopy at 7 yrs in a high risk cohort

Pediatric Allergy and Immunology

Ferguson, A. and Dimich-Ward, H. and Becker, A. and Watson, W. and Dybuncio, A. and Carlsten, C. and Chan-Yeung, M.

DOI: 10.1111/j.1399-3038.2009.00869.x

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

Journal of Allergy and Clinical Immunology

Odhiambo, J.A. and Williams, H.C. and Clayton, T.O. and Robertson, C.F. and Asher, M.I. and A?t-Khaled, N. and Anderson, H.R. and Beasley, R. and Bj ? Rkst?n, B. and Brunekreef, B. and Crane, J. and Ellwood, P. and Flohr, C. and Foliaki, S. and Forastiere, F. and Garc?a-Marcos, L. and Keil, U. and Lai, C.K.W. and Mallol, J. and Mitchell, E.A. and Montefort, S. and Pearce, N. and Stewart, A.W. and Strachan, D. and von Mutius, E. and Weiland, S.K. and Weinmayr, G. and Wong, G. and Priftanji, A. and Benhabyl?s, B. and Baena-Cagnani, C.E. and Crisci, C.D. and G?mez, M. and Zabert, G.E. and Haidinger, G. and Howitt, M.E. and Weyler, J. and Pinto-Vargas, R. and Bernhardt, C.D.S.D. and Borges, W.G. and Camargos, P.A.M. and Cardoso, M.D.S. and Cunha, A.J.L.A. and Fischer, G.B. and Motta, J.M. and Neto, A.P. and Passos, F.J. and Pastorino, A.C. and Ros?rio, N. and Silva, A. and Sol?, D. and Wandalsen, N. and de Britto, M. and de Freitas Souza, L. and Popov, T. and Kuaban, C. and Ferguson, A. and Rennie, D. and Goulding, R. and Standring, P. and Aguilar, P. and Amarales, L. and Benavides, L.A.V. and Calvo, M.A. and Contreras, A. and Chen, Y.-Z. and Kunii, O. and Li Pan, Q. and Zhong, N.-S. and Aristiz?bal, G. and Cepeda, A.M. and Ordo?ez, G.A. and M??boussa, J. and Daniel, R. and Soto-Quir?s, M.E. and Koffi, B.N. and Lah Tomulic, K. and Varona Per?z, P. and Barba, S. and Bustos, C. and Naguib, M.L. and Figueroa Colorado, M. and Riikj?rv, M.-A. and Melaku, K. and Sa??aga-Banuve, R. and Pekkanen, J. and Vlaski, E. and Hypolite, I.E. and Gotua, M. and Tsanakas, J. and Bueso-Engelhardt, A. and Lau, Y.L. and Novk, Z. and Zsigmond, G. and Awasthi, S. and Bhave, S. and Chhatwal, J. and Hanumante, N.M. and Jain, K.C. and Joshi, M.K. and Khatav, V.A. and Kumar, L. and Mantri, S.N. and Pherwani, A.V. and Rego, S. and Sabir, M. and Salvi, S. and Setty, G. and Sharma, S.K. and Singh, V. and Sukumaran, T.U. and Suresh Babu, P.S. and Kartasasmita, C.B. and Konthen, P. and Suprihati, W. and Masjedi, M.-R. and Steriu, A. and Armenio, L. and Bisanti, L. and Bonci, E. and Chellini, E. and Ciccone, G. and Dell??orco, V. and Galassi, C. and Giannella, G. and La Grutta, S. and Petronio, M.G. and Piffer, S. and Sestini, P. and Abu-Ekteish, F. and Esamai, F.O. and Ng??ang??a, L. and Al-Momen, J.A. and Imanalieva, C. and Sulaimanov, S. and Svabe, V. and Bojarskas, J. and Kudzyte, J. and Quah, B.S. and Teh, K.H. and de Bruyne, J. and Baeza-Bacab, M. and Barrag?n-Meijueiro, M. and Del-R?o-navarro, B.E. and Garc?a-Almaraz, R. and Gonz?lez-D?az, S.N. and Linares-Zapi?n, F.J. and Merida-Palacio, J.V. and Ram?rez-Chanona, N. and Romero-Tapia, S. and Romieu, I. and Bouayad, Z. and Engels, R. and Mackay, R. and Moyes, C. and Pattemore, P. and S?nchez, J.F. and Onadeko, B.O. and Magatogia, M. and Annesi-Maesano, I. and Mahmood, N. and Yusuf, M.O. and El Sharif, N. and Mortaja, S. and Cukier, G. and Guggiari-Chase, J.A. and Chiarella, P. and Cua-Lim, F. and Br?borowicz, A. and Lis, G. and Chiera, M.L. and C?mara, R. and Lopes Dos Santos, J.M. and Nunes, C. and Rosado Pinto, J.E. and Clancy, L. and Kayembe, J.-M. and Deleanu, D. and Kondiourina, E.G. and Sow, O.Y. and Fuimaono, P. and Adzovic, O. and Hadnadjev, M. and Panic, E. and Zivanovic, S. and Zivkovic, Z. and Goh, D.Y.T. and Voyi, K. and Zar, H.J. and Lee, H.-B. and Arnedo-Pena, A. and Batlles-Garrido, J. and Blanco Quir?s, A. and Busquets, R.M. and Carvajal-Urue?a, I. and Garcia-Hern?ndez, G. and Gonz?lez D?az, C. and Guill?n-Grima, F. and L?pez-Silvarrey Varela, A. and Morales Su?rez-Varela, M.M. and P?rez-Yarza, E.G. and Gunasekera, K.D. and Musa, O.A.A. and Al-Rawas, O. and Vogt, H. and Mohammad, S. and Mohammad, Y. and Tabbah, K. and Huang, J.-L. and Kao, C.-C. and Kongpanichkul, A. and Nettagul, R. and Prasarnphanich, T. and Teeratakulpisarn, J. and Trakultivakorn, M. and Vichyanond, P. and Tidjani, O. and Iosefa, T. and Monteil, M.A. and Jerray, M. and Khaldi, F. and Redding, G.J. and Windom, H.H. and Ognev, V. and Austin, J.B. and Burr, M. and Shamssain, M.H. and Holgado, D. and Lapides, M.C. and Aldrey, O. and Va?n Cam, B. and Sears, M. and Aguirre, V. and Ahel, V. and Gratziou, C. and Shah, J. and Baratawidjaja, K. and Fakakovi, T. and Otten, R. and Barny, S. and Chansin, R. and Manning, P. and Bahati, E. and Khaitov, R.M. and Tuuau-Potai, N. and Lee, B.-W. and El Sony, A. and Nilsson, L.

DOI: 10.1016/j.jaci.2009.10.009

Early environmental determinants of asthma risk in a high-risk birth cohort

Pediatric Allergy and Immunology

Chan-Yeung, M. and Hegele, R.G. and Dimich-Ward, H. and Ferguson, A. and Schulzer, M. and Chan, H. and Watson, W. and Becker, A.

DOI: 10.1111/j.1399-3038.2007.00689.x

Prevalence of asthma among Chinese adolescents living in Canada and in China

CMAJ

Wang, H.-Y. and Wong, G.W.K. and Chen, Y.-Z. and Ferguson, A.C. and Greene, J.M. and Ma, Y. and Zhong, N.-S. and Lai, C.K.W. and Sears, M.R.

DOI: 10.1503/cmaj.071797

Relationship of early childhood viral exposures to respiratory symptoms, onset of possible asthma and atopy in high risk children: The Canadian asthma primary prevention study

Pediatric Pulmonology

Lee, K.K. and Hegele, R.G. and Manfreda, J. and Wooldrage, K. and Becker, A.B. and Ferguson, A.C. and Dimich-Ward, H. and Watson, W.T.A. and Chan-Yeung, M.

DOI: 10.1002/ppul.20578

A comparison of the relative growth velocities with budesonide and fluticasone propionate in children with asthma

Respiratory Medicine

Ferguson, A.C. and Van Bever, H.P. and Teper, A.M. and Lasytsya, O. and Goldfrad, C.H. and Whitehead, P.J.

DOI: 10.1016/j.rmed.2006.04.009

The Canadian Childhood Asthma Primary Prevention Study: Outcomes at 7 years of age

Journal of Allergy and Clinical Immunology

Chan-Yeung, M. and Ferguson, A. and Watson, W. and Dimich-Ward, H. and Rousseau, R. and Lilley, M. and DyBuncio, A. and Becker, A.

DOI: 10.1016/j.jaci.2005.03.029

A modified vaccine reduces the rate of large injection site reactions to the preschool booster dose of diphtheria-tetanus-acellular pertussis vaccine: Results of a randomized, controlled trial

Pediatric Infectious Disease Journal

Scheifele, D.W. and Halperin, S.A. and Ochnio, J.J. and Ferguson, A.C. and Skowronski, D.M.

DOI: 10.1097/01.inf.0000190028.96152.46

The Canadian asthma primary prevention study: Outcomes at 2 years of age

Journal of Allergy and Clinical Immunology

Becker, A. and Watson, W. and Ferguson, A. and Dimich-Ward, H. and Chan-Yeung, M.

DOI: 10.1016/j.jaci.2004.01.754

Genetic variants of the IL13 and IL4 genes and atopic diseases in at-risk children

Genes and Immunity

He, J.-Q. and Chan-Yeung, M. and Becker, A.B. and Dimich-Ward, H. and Ferguson, A.C. and Manfreda, J. and Watson, W.T.A. and Sandford, A.J.

DOI: 10.1038/sj.gene.6363985

Effectiveness of and compliance to intervention measures in reducing house dust and cat allergen levels

Annals of Allergy, Asthma and Immunology

Chan-Yeung, M. and Dimich-Ward, H. and Ferguson, A. and Watson, W. and Becker, A. and Manfreda, J.

DOI: 10.1016/S1081-1206(10)63592-2

Letter to the Editor [multiple letter]

Canadian Journal of Allergy and Clinical Immunology

Ham Pong, A.J. and Ferguson, A.C.

The role of symptomatic colds in asthma exacerbations: Influence of outdoor allergens and air pollutants

Journal of Allergy and Clinical Immunology

Tarlo, S.M. and Broder, I. and Corey, P. and Chan-Yeung, M. and Ferguson, A. and Becker, A. and Rogers, C. and Okada, M. and Manfreda, J.

DOI: 10.1067/mai.2001.116574

Assessment of injection site reactions to an acellular pertussis-based combination vaccine, including novel use of skin tests with vaccine antigens

Vaccine

Scheifele, D.W. and Halperin, S.A. and Ferguson, A.C.

DOI: 10.1016/S0264-410X(01)00230-4

The association between respiratory viruses and symptoms in 2-week-old infants at high risk for asthma and allergy

Journal of Pediatrics

Hegele, R.G. and Ahmad, H.Y. and Becker, A.B. and Dimich-Ward, H. and Ferguson, A.C. and Manfreda, J. and Watson, W.T.A. and Chan-Yeung, M.

DOI: 10.1067/mpd.2001.114479

Asthma, breastfeeding, and hypoallergenic formula [7] (multiple letters)

Archives of Pediatrics and Adolescent Medicine

Donnelly, B.W. and Chan-Yeung, M. and Dimich-Ward, H. and Ferguson, A. and Manfreda, J. and Watson, W. and Becker, A.

Cord blood IgE: Its determinants and prediction of development of asthma and other allergic disorders at 12 months

Annals of Allergy, Asthma and Immunology

Kaan, A. and Dimich-Ward, H. and Manfreda, J. and Becker, A. and Watson, W. and Ferguson, A. and Chan, H. and Chan-Yeung, M.

DOI: 10.1016/S1081-1206(10)62738-X

A randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants

Archives of Pediatrics and Adolescent Medicine

Chan-Yeung, M. and Manfreda, J. and Dimich-Ward, H. and Ferguson, A. and Watson, W. and Becker, A.

DOI: 10.1001/archpedi.154.7.657

Polymorphisms of the IL-4, TNF-a, and FceRI genes and the risk of allergic disorders in at-risk infants

American Journal of Respiratory and Critical Care Medicine

Zhu, S. and Chan-Yeung, M. and Becker, A.B. and Dimich-Ward, H. and Ferguson, A.C. and Manfreda, J. and Watson, W.T.A. and Par, P.D. and Sandford, A.J.

DOI: 10.1164/ajrccm.161.5.9906086

Outcome of peanut allergy in infancy: An oral challenge study in school age children

Canadian Journal of Allergy and Clinical Immunology

Koetzler, R. and Ferguson, A.C.

Breast-feeding and environmental tobacco smoke exposure

Archives of Pediatrics and Adolescent Medicine

Becker, A.B. and Manfreda, J. and Ferguson, A.C. and Dimich-Ward, H. and Watson, W.T.A. and Chan-Yeung, M.

DOI: 10.1001/archpedi.153.7.689

Umbilical cord blood mononuclear cell proliferative response to house dust mite does not predict the development of allergic rhinitis and asthma

Journal of Allergy and Clinical Immunology

Chan-Yeung, M. and Ferguson, A. and Chan, H. and Dimich-Ward, H. and Watson, W. and Manfreda, J. and Becker, A.

DOI: 10.1016/S0091-6749(99)70373-8

Summary of recommendations from the Canadian Asthma Consensus Report, 1999

CMAJ

Boulet, L.-P. and Becker, A. and Berube, D. and Beveridge, R. and Ernst, P. and Acres, J.C. and Bai, T.R. and Balter, M.S. and Bouchard, J. and Boulet L.-, P. and Bowie, D.M. and Busse, W.W. and Cartier, A. and Cave, A.J. and Chan-Yeung, M. and Chapman, K.R. and Chernick, V. and Cockcroft, D.W. and Cote, J. and Cowie, R.L. and Day, A. and Dean, M.M. and Dolovich, M. and Drouin, D. and Ducharme, F. and Duiguid, N.J. and D'Urzo, A.D. and Dyck, G.H. and Ferguson, A.C. and Fitzgerald, J.M. and Grunfeld, A.F. and Hargreave, F.E. and Hodder, R.V. and Hoey, J. and Hughes, D. and Hyland, R.H. and Jin, R. and Kaplan, A. and Hill, R. and Kolbe, J. and Kovesi, T. and Kvern, B.L. and Leith, E.S. and Leung, A. and MacLusky, I.B. and Majaesic, C.M. and Man, S.F.P. and Noya, F.J.D. and O'Byrne, P. and Owen, J.G. and Peters, S.D. and Rivard, G.B. and Rouleau, M.-Y. and Schellenberg, R. and Sears, M.R. and Simons, E.R. and Slutsky, A. and Spier, S. and Thivierge, R.L. and Toogood, J.H. and Turgeon, M. and Warren, D.W. and Wenzel, S.E. and Zimmerman, B.

Efficacy and safety of high-dose inhaled steroids in children with asthma: A comparison of fluticasone propionate with budesonide

Journal of Pediatrics

Ferguson, A.C. and Spier, S. and Manjra, A. and Versteegh, F.G.A. and Mark, S. and Zhang, P.

DOI: 10.1016/S0022-3476(99)70198-8

Effect of application of benzyl benzoate on house dust mite allergen levels

Annals of Allergy, Asthma and Immunology

Chang, J.H. and Becker, A. and Ferguson, A. and Manfreda, J. and Simons, E. and Chan, H. and Noertjojo, K. and Chan-Yeung, M.

DOI: 10.1016/S1081-1206(10)63253-X

Changes in peak flow, symptom score, and the use of medications during acute exacerbations of asthma

American Journal of Respiratory and Critical Care Medicine

Chan-Yeung, M. and Chang, J.H. and Manfreda, J. and Ferguson, A. and Becker, A.

DOI: 10.1164/ajrccm.154.4.8887581

The role of colds and air pollutants in acute asthma exacerbations

Chest

Tarlo, S.M. and Broder, I. and Corey, P. and Yeung, M. and Becker, A. and Ferguson, A. and Warren, P. and Manfreda, J.

Mite and cat allergen levels in homes and severity of asthma

American Journal of Respiratory and Critical Care Medicine

Chan-Yeung, M. and Manfreda, J. and Dimich-Ward, H. and Lam, J. and Ferguson, A. and Warren, P. and Simons, E. and Broder, I. and Chapman, M. and Platts-Mills, T. and Becker, A.

DOI: 10.1164/ajrccm.152.6.8520740

Evaluation of serum eosinophilic cationic protein as a marker of disease activity in chronic asthma

The Journal of Allergy and Clinical Immunology

Ferguson, A.C. and Vaughan, R. and Brown, H. and Curtis, C.

DOI: 10.1016/S0091-6749(95)70148-6

Major cat allergen (Fel d I) levels in the homes of patients with asthma and their relationship to sensitization to cat dander

Annals of Allergy, Asthma and Immunology

Quirce, S. and Dimich-Ward, H. and Chan, H. and Ferguson, A. and Becker, A. and Manfreda, J. and Simons, E. and Chan-Yeung, M.

House dust mite allergen levels in two cities in Canada: Effects of season, humidity, city and home characteristics

Clinical and Experimental Allergy

Chan-Yeung, M. and Becker, A. and Lam, J. and Dimich-Ward, H. and Ferguson, A. and Warren, P. and Simons, E. and Broder, I. and Manfreda, J.

DOI: 10.1111/j.1365-2222.1995.tb01035.x

Criteria for labelling infant formulas as 'hypoallergenic'

CMAJ

Chad, Z. and Ferguson, A. and Simons, F.E.R. and Watson, W.T.A.

Is there a role for early therapeutic intervention in childhood asthma?

Annals of the Royal College of Physicians and Surgeons of Canada

Ferguson, A.C. and Price, J.F. and Mitchell, I.

Hypersensitivity reaction to single contrast barium meal studies in children

Pediatric Radiology

Stringer, D.A. and Hassall, E. and Ferguson, A.C. and Cairns, R. and Nadel, H. and Sargent, M.

DOI: 10.1007/BF02014970

Adverse reactions to food in infancy and childhood: Session I: Discussion

Journal of Pediatrics

Ferguson, A. and Savilahti, E. and Businco, L. and Pascual, C.

DOI: 10.1016/S0022-3476(05)81404-0

Correlation of bronchial eosinophil and mast cell activation with bronchial hyperresponsiveness in children with asthma

The Journal of Allergy and Clinical Immunology

Ferguson, A.C. and Whitelaw, M. and Brown, H.

DOI: 10.1016/0091-6749(92)90133-M

Treatment of chronic asthma in children: The changing role of inhaled corticosteroids [3]

CMAJ

Cook, D.J. and Simons, F.E.R. and Chad, Z.H. and Ferguson, A.C. and Luciuk, G.H. and Murray, A.B. and Watson, W.T.A.

Expert nursing care: some reflections.

The Australian nurses" journal

Fallas, E. and Ferguson, A. and Gerlach, F. and Kriels, J. and Ellis, E. and Williams, J.

Treatment of chronic asthma in children: The changing role of inhaled corticosteroids

CMAJ

Simons, F.E.R. and Chad, Z.H. and Ferguson, A.C. and Luciuk, G.H. and Murray, A.B. and Watson, W.T.A.

Blood tests for allergy in children

CMAJ

Simons, E. and Chad, Z. and Ferguson, A.C. and Luciuk, G. and Murray, A.

Bronchial hyperresponsiveness in asthmatic children. Correlation with macrophages and eosinophils in broncholavage fluid

Chest

Ferguson, A.C. and Wong, F.W.M.

DOI: 10.1378/chest.96.5.988

Persisting airway obstruction in asymptomatic children with asthma with normal peak expiratory flow rates

The Journal of Allergy and Clinical Immunology

Ferguson, A.C.

DOI: 10.1016/0091-6749(88)90045-0

Predictive value of skin prick tests and radioallergosorbent tests for clinical allergy to dogs and cats

Canadian Medical Association Journal

Ferguson, A.C. and Murray, A.B.

Non-allergic bronchial hyperreactivity in asthmatic children decreases with age and increases with mite immunotherapy

Annals of Allergy

Murray, A.B. and Ferguson, A.C. and Morrison, B.J.

Sensitization to house dust mites in different climatic areas

The Journal of Allergy and Clinical Immunology

Murray, A.B. and Ferguson, A.C. and Morrison, B.J.

DOI: 10.1016/0091-6749(85)90812-7

Food allergy.

Progress in Food and Nutrition Science

Ferguson, A.C.

Elevated IgG immune complexes in children with atopic eczema

The Journal of Allergy and Clinical Immunology

Ferguson, A.C. and Salinas, F.A.

DOI: 10.1016/0091-6749(84)90229-X

Reply

The Journal of Allergy and Clinical Immunology

Murray, A.B. and Ferguson, A.C. and Morrison, B.J.

DOI: 10.1016/0091-6749(84)90419-6

Diagnosis of house dust mite allergy in asthmatic children: what constitutes a positive history?

The Journal of Allergy and Clinical Immunology

Murray, A.B. and Ferguson, A.C. and Morrison, B.J.

DOI: 10.1016/0091-6749(83)90542-0

Why are children more often allergic to cats than to dogs?

Canadian Medical Association journal

Murray, A.B. and Ferguson, A.C. and Morrison, B.J.

The frequency and severity of cat allergy vs. dog allergy in atopic children

The Journal of Allergy and Clinical Immunology

Murray, A.B. and Ferguson, A.C. and Morrison, B.J.

DOI: 10.1016/0091-6749(83)90522-5

Dust-free bedrooms in the treatment of asthmatic children with house dust or house dust mite allergy: A controlled trial

Pediatrics

Murray, A.B. and Ferguson, A.C.

REDUCTION OF BRONCHIAL HYPERREACTIVITY DURING PROLONGED ALLERGEN AVOIDANCE

The Lancet

Murray, A. and Ferguson, A.

DOI: 10.1016/S0140-6736(82)91220-X

Short stature and delayed skeletal maturation in children with allergic disease

The Journal of Allergy and Clinical Immunology

Ferguson, A.C. and Murray, A.B. and Tze, W.-J.

DOI: 10.1016/0091-6749(82)90122-1

Decreased theophylline induced suppression of IgM synthesis in allergic disease

Journal of Allergy and Clinical Immunology

Ferguson, A.C. and Cheung, S.C.

A comparison of spirometric measurements in allergen bronchial challenge testing

Clinical & Experimental Allergy

MURRAY, A.B. and FERGUSON, A.C.

DOI: 10.1111/j.1365-2222.1981.tb01570.x

Modulation of immunoglobulin M and G synthesis by monocytes and T lymphocytes in the newborn infant

The Journal of Pediatrics

Ferguson, A.C. and Cheung, S.-S.C.

DOI: 10.1016/S0022-3476(81)80700-7

Airway responsiveness to histamine as a test for overall severity of asthma in children

The Journal of Allergy and Clinical Immunology

Murray, A.B. and Ferguson, A.C. and Morrison, B.

DOI: 10.1016/0091-6749(81)90169-X

The seasonal variation of allergic respiratory symptoms induced by house dust mites

Annals of Allergy

Murray, A.B. and Ferguson, A.C. and Morrison, B.

Is mite hypersensitivity sex-linked in children?

Clinical Allergy

Murray, A.B. and Ferguson, A.C. and Morrison, B.

Letter to the Editor

Clinical & Experimental Allergy

Murray, A.B. and Ferguson, A.C. and Morrison, B.

DOI: 10.1111/j.1365-2222.1980.tb02131.x

Prolonged impairment of cellular immunity in children with intrauterine growth retardation

The Journal of Pediatrics

Ferguson, A.C.

DOI: 10.1016/S0022-3476(78)80599-X

Psychiatric nursing: the myth today.

Nursing times

Ferguson, A.

Cellular immunity and nutrition in refractory disseminated blastomycosis

Canadian Medical Association Journal

FitzSimons, R.B. and Ferguson, A.C.

Correlation of cutaneous hypersensitivity with lymphocytic response to Candida albicans

American Journal of Clinical Pathology

Ferguson, A.C. and Kershnar, H.E. and Collin, W.K. and Stiehm, E.R.

DOI: 10.1093/ajcp/68.4.499

Serotonin metabolism in cystic fibrosis

Archives of Disease in Childhood

Partington, M.W. and Ferguson, A.C.

DOI: 10.1136/adc.52.5.386

De-schooling nurses.

Nursing times

Ferguson, A.C.

Detection of fibrin degradation products. A comparison of counterimmunoelectrophoresis and two hemagglutination inhibition methods

American Journal of Clinical Pathology

Ferguson, A.C. and Kennedy, H. and Ank, B.J. and Sturgeon, P. and Stiehm, E.R.

DOI: 10.1093/ajcp/62.6.861

Decreased rosette-forming lymphocytes in malnutrition and intrauterine growth retardation

The Journal of Pediatrics

Ferguson, A.C. and Lawlor Jr., G.J. and Neumann, C.G. and Oh, W. and Stiehm, E.R.

DOI: 10.1016/S0022-3476(74)80527-5

Hereditary Nephropathy With Nerve Deafness (Alport's Syndrome)

American Journal of Diseases of Children

Ferguson, A.C. and Rance, C.P.

DOI: 10.1001/archpedi.1972.02110130086013

Nursing education in EEC countries,Sygeplejerske-uddannelsen i EF-landene.

Sygeplejersken

Ferguson, A.C.

The Common Market and nurses. 2,Faellesmarkedet og sygeplejerskerne. 2.

Sygeplejersken

Ferguson, A.C.

Common Market and nurses. 2.

Nursing times

Ferguson, A.C.

Common Market and Nurses. 1.

Nursing times

Ferguson, A.C.

Current Projects

Development of a novel method for assessing levels of nitric oxide in nasal air which can be used as a non-invasive test for nasal allergy and inflammation.

Current Projects

Randomized, controlled studies comparing the efficacy and adverse effects of different inhaled corticosteroids for asthma. Recent findings are of a progressive decrease in growth velocity in school aged children over a 12-month treatment period with one commonly used medication compared to another.

Current Projects

A multifaceted intervention study starting before birth in 500 children who are at high risk of developing asthma and allergy has been in progress since 1995, with the most recent assessment (age 7 years) currently underway. The study assesses the effect on asthma and allergy symptoms and development of specific allergies and bronchial hyperresponsiveness, growth and development and genetic markers.Early findings are of a 35% reduction in wheezing illness at age 2 to 4 years and an increased proportion of children with specific susceptibility genes.

Honours & Awards

Best Doctors in Canada - 1998

Charles T. Fried Lectureship, University of Alberta - 1991

Our Research

At BC Children’s, we are making discoveries that save lives and transform health care for children in our province and around the world. Our research portfolio includes basic, clinical, population, and public health research.

EXPLORE OUR RESEARCH

Alexander C. Ferguson

FRCPC, MBChB

Investigator Emeritus, BC Children's Hospital

Academic Affiliations

Contact Information

Location

Publications

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Are environmental risk factors for current wheeze in the International Study of Asthma and Allergies in Childhood (ISAAC) phase three due to reverse causation?

Are Environmental Factors for Atopic EczemainISAAC Phase Three due to ReverseCausation?

Association between Frequency of Consumption of Fruit, Vegetables, Nuts and Pulses and BMI: Analyses of the International Study of Asthma and Allergies in Childhood (ISAAC).

Body mass index and vigorous physical activity in children and adolescents: an international cross-sectional study

Maternal post-natal tobacco use and current parental tobacco use is associated with higher body mass index in children and adolescents: an international cross-sectional study

Atopic dermatitis in a high-risk cohort: Natural history, associated allergic outcomes, and risk factors

Association between endotoxin and mite allergen exposure with asthma and specific sensitization at age 7 in high-risk children

Airway hyperresponsiveness to methacholine in 7-year-old children: Sensitivity and specificity for pediatric allergist-diagnosed asthma

Disparate geographic prevalences of asthma, allergic rhinoconjunctivitis and atopic eczema among adolescents in five Canadian cities

Indoor allergen exposure, sensitization, and development of asthma in a high-risk birth cohort

Elevated cord blood IgE is associated with recurrent wheeze and atopy at 7 yrs in a high risk cohort

Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three

Early environmental determinants of asthma risk in a high-risk birth cohort

Prevalence of asthma among Chinese adolescents living in Canada and in China

Relationship of early childhood viral exposures to respiratory symptoms, onset of possible asthma and atopy in high risk children: The Canadian asthma primary prevention study

A comparison of the relative growth velocities with budesonide and fluticasone propionate in children with asthma

The Canadian Childhood Asthma Primary Prevention Study: Outcomes at 7 years of age

A modified vaccine reduces the rate of large injection site reactions to the preschool booster dose of diphtheria-tetanus-acellular pertussis vaccine: Results of a randomized, controlled trial

The Canadian asthma primary prevention study: Outcomes at 2 years of age

Genetic variants of the IL13 and IL4 genes and atopic diseases in at-risk children

Effectiveness of and compliance to intervention measures in reducing house dust and cat allergen levels

Letter to the Editor [multiple letter]

The role of symptomatic colds in asthma exacerbations: Influence of outdoor allergens and air pollutants

Assessment of injection site reactions to an acellular pertussis-based combination vaccine, including novel use of skin tests with vaccine antigens

The association between respiratory viruses and symptoms in 2-week-old infants at high risk for asthma and allergy

Asthma, breastfeeding, and hypoallergenic formula [7] (multiple letters)

Cord blood IgE: Its determinants and prediction of development of asthma and other allergic disorders at 12 months

A randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants

Polymorphisms of the IL-4, TNF-a, and FceRI genes and the risk of allergic disorders in at-risk infants

Outcome of peanut allergy in infancy: An oral challenge study in school age children

Breast-feeding and environmental tobacco smoke exposure

Umbilical cord blood mononuclear cell proliferative response to house dust mite does not predict the development of allergic rhinitis and asthma

Summary of recommendations from the Canadian Asthma Consensus Report, 1999

Efficacy and safety of high-dose inhaled steroids in children with asthma: A comparison of fluticasone propionate with budesonide

Effect of application of benzyl benzoate on house dust mite allergen levels

Changes in peak flow, symptom score, and the use of medications during acute exacerbations of asthma

The role of colds and air pollutants in acute asthma exacerbations

Mite and cat allergen levels in homes and severity of asthma

Evaluation of serum eosinophilic cationic protein as a marker of disease activity in chronic asthma

Major cat allergen (Fel d I) levels in the homes of patients with asthma and their relationship to sensitization to cat dander

House dust mite allergen levels in two cities in Canada: Effects of season, humidity, city and home characteristics

Criteria for labelling infant formulas as 'hypoallergenic'

Is there a role for early therapeutic intervention in childhood asthma?

Hypersensitivity reaction to single contrast barium meal studies in children

Adverse reactions to food in infancy and childhood: Session I: Discussion

Correlation of bronchial eosinophil and mast cell activation with bronchial hyperresponsiveness in children with asthma

Treatment of chronic asthma in children: The changing role of inhaled corticosteroids [3]

Expert nursing care: some reflections.

Treatment of chronic asthma in children: The changing role of inhaled corticosteroids

Blood tests for allergy in children

Bronchial hyperresponsiveness in asthmatic children. Correlation with macrophages and eosinophils in broncholavage fluid

Persisting airway obstruction in asymptomatic children with asthma with normal peak expiratory flow rates

Predictive value of skin prick tests and radioallergosorbent tests for clinical allergy to dogs and cats

Non-allergic bronchial hyperreactivity in asthmatic children decreases with age and increases with mite immunotherapy

Sensitization to house dust mites in different climatic areas

Food allergy.

Elevated IgG immune complexes in children with atopic eczema

Reply

Diagnosis of house dust mite allergy in asthmatic children: what constitutes a positive history?

Why are children more often allergic to cats than to dogs?

The frequency and severity of cat allergy vs. dog allergy in atopic children

Dust-free bedrooms in the treatment of asthmatic children with house dust or house dust mite allergy: A controlled trial

REDUCTION OF BRONCHIAL HYPERREACTIVITY DURING PROLONGED ALLERGEN AVOIDANCE

Short stature and delayed skeletal maturation in children with allergic disease

Decreased theophylline induced suppression of IgM synthesis in allergic disease

A comparison of spirometric measurements in allergen bronchial challenge testing

Modulation of immunoglobulin M and G synthesis by monocytes and T lymphocytes in the newborn infant

Airway responsiveness to histamine as a test for overall severity of asthma in children

The seasonal variation of allergic respiratory symptoms induced by house dust mites

Is mite hypersensitivity sex-linked in children?

Letter to the Editor