Ashutosh Singhal

MSc, MD, FRCSC

Investigator, BC Children's Hospital

Dr. Singhal is involved and interested in a multitude of pediatric neurosurgery topics, however his main interests are head injuries and their causes, consequences and interactions with the environment. His research employs leading-edge imaging technologies as well as the study of potentially underlying environmental and genomic factors that may contribute to disease progression and outcome. Another major research focus is the monitoring and study of post-operative status, management and outcome of neurosurgery patients.

Academic Affiliations

  • Clinical Associate Professor, Division of Pediatric Neurosurgery, Department of Surgery, Faculty of Medicine, University of British Columbia
  • Research Theme: Brain, Behaviour & Development

Contact Information

Location

4500 Oak St, Vancouver, BC, Canada, V6H 3N1

Improving access to epilepsy surgery: a review of the global praxis, implementation science, and relevant policy frameworks

Neurosurgical Focus

Ferraris, K.P. and Mabilangan, K.C. and Gimenez, M.L.A. and Ra{\~n}oa, G.J. and Aguilar, J.F.A. and Go, C.Y. and Connolly, M. and Zipfel, J. and Haji, F.A. and Tamber, M.S. and Singhal, A.

DOI: 10.3171/2025.1.FOCUS24805

Intraoperative Ultrasound in Endoscopic Sagittal Suture Synostosis to Optimize Incision Planning and Avoid Misdiagnosis

Journal of Craniofacial Surgery

Zipfel, J. and Ferraris, K.P. and Thompson, A. and Singhal, A.

DOI: 10.1097/SCS.0000000000010560

Rhizotomy Surgery at the Conus Medullaris

Advances and Technical Standards in Neurosurgery

Ferraris, K.P. and Singhal, A.

DOI: 10.1007/978-3-031-86441-4_8

Polka Dot Intracerebral Hemorrhage in Leukemia

Stroke

Rebchuk, A.D. and Singhal, A. and Tamber, M.S.

DOI: 10.1161/STROKEAHA.124.049631

Global trends and decision-making in the management of arachnoid cysts

Child's Nervous System

Kakodkar, P. and Ragulojan, M. and Hayawi, L. and Tsampalieros, A. and Chee, S.S. and Wu, M. and Makoshi, Z. and Singhal, A. and Steinbok, P. and Fallah, A. and Robison, R.A. and Tu, A.

DOI: 10.1007/s00381-023-06212-8

Central Nervous System Germ Cell Tumors (CNS GCTs)

Pediatric Neuro Oncology 2nd Ed

Cheng, S. and Singhal, A. and Bartels, U.

DOI: 10.1007/978-3-031-62017-1_15

A re-evaluation of the Endoscopic Third Ventriculostomy Success Score: a Hydrocephalus Clinical Research Network study

Journal of Neurosurgery: Pediatrics

Verhey, L.H. and Kulkarni, A.V. and Reeder, R.W. and Riva-Cambrin, J. and Jensen, H. and Pollack, I.F. and Rocque, B.G. and Tamber, M.S. and McDonald, P.J. and Krieger, M.D. and Pindrik, J.A. and Hauptman, J.S. and Browd, S.R. and Whitehead, W.E. and Jackson, E.M. and Wellons, J.C. and Hankinson, T.C. and Chu, J. and Limbrick, D.D. and Strahle, J.M. and Kestle, J.R.W. and Brockmeyer, D. and Walker, M. and Bollo, R. and Cheshier, S. and Blount, J. and Johnston, J. and Acakpo-Satchivi, L. and Oakes, W.J. and Dirks, P. and Rutka, J. and Taylor, M. and Curry, D. and Aldave, G. and Dauser, R. and Jea, A. and Lam, S. and Weiner, H. and Luerssen, T. and Ellenbogen, R. and Ojemann, J. and Lee, A. and Avellino, A. and Greene, S. and Tyler-Kabara, E. and Abel, T. and Park, T.S. and McEvoy, S. and Smyth, M. and Tulipan, N. and Singhal, A. and Steinbok, P. and Cochrane, D. and Hader, W. and Gallagher, C. and Benour, M. and Kiehna, E. and McComb, J.G. and Chiarelli, P. and Robison, A. and Alexander, A. and Handler, M. and O?Neill, B. and Wilkinson, C. and Governale, L. and Drapeau, A. and Leonard, J. and Sribnick, E. and Shaikhouni, A. and Ahn, E. and Cohen, A. and Groves, M. and Robinson, S. and Bonfield, C.M. and Shannon, C.

DOI: 10.3171/2023.12.PEDS23401

Withdrawal of Life-Sustaining Treatment for Pediatric Patients with Severe Traumatic Brain Injury

JAMA Surgery

Nathens, A.B. and Malhotra, A.K. and Shakil, H. and Smith, C.W. and Sader, N. and Ladha, K. and Wijeysundera, D.N. and Singhal, A. and Kulkarni, A.V. and Wilson, J.R. and Witiw, C.D.

DOI: 10.1001/jamasurg.2023.6531

Optic nerve sheath diameter correlates with both success and failure of hydrocephalus treatment in pediatric patients with pineal region lesions

Acta Neurochirurgica

Zipfel, J. and Kerscher, S.R. and Dhillon, K. and Ferraris, K.P. and Singhal, A.

DOI: 10.1007/s00701-024-06122-x

Patient-Reported Outcome Measures More Than Fifteen Years After Treatment of Sagittal or Metopic Craniosynostosis: A Prospective Cohort Study

Research Square

Woerdeman, P.A. and Klieverik, V.M. and Cheong, A. and Singhal, A. and Cochrane, D. and Steinbok, P.

DOI: 10.21203/rs.3.rs-3296264/v1

Treatment of hydrocephalus following posterior fossa tumor resection: a multicenter collaboration from the Hydrocephalus Clinical Research Network

Journal of Neuro-Oncology

Dewan, M.C. and Isaacs, A.M. and Cools, M.J. and Yengo-Kahn, A. and Naftel, R.P. and Jensen, H. and Reeder, R.W. and Holubkov, R. and Haizel-Cobbina, J. and Riva-Cambrin, J. and Jafrani, R.J. and Pindrik, J.A. and Jackson, E.M. and Judy, B.F. and Kurudza, E. and Pollack, I.F. and Mcdowell, M.M. and Hankinson, T.C. and Staulcup, S. and Hauptman, J. and Hall, K. and Tamber, M.S. and Cheong, A. and Warsi, N.M. and Rocque, B.G. and Saccomano, B.W. and Snyder, R.I. and Kulkarni, A.V. and Kestle, J.R.W. and Wellons, J.C. and Brockmeyer, D. and Walker, M. and Bollo, R. and Cheshier, S. and Iyer, R. and Blount, J. and Johnston, J. and Rocque, B. and Acakpo-Satchivi, L. and Oakes, W.J. and Dirks, P. and Ibrahim, G. and Rutka, J. and Taylor, M. and Curry, D. and Aldave, G. and Dauser, R. and Jea, A. and Lam, S. and Weiner, H. and Luerssen, T. and Ellenbogen, R. and Ojemann, J. and Lee, A. and Avellino, A. and Greene, S. and McDowell, M. and Tyler-Kabara, E. and Kellogg, R. and Abel, T. and Park, T.S. and Strahle, J. and Roland, J. and McEvoy, S. and Smyth, M. and Tulipan, N. and Haji, F. and Singhal, A. and Steinbok, P. and Cochrane, D. and Hader, W. and Gallagher, C. and Benour, M. and Chiarelli, P. and Durham, S. and Kiehna, E. and McComb, J.G. and Robison, A. and Alexander, A. and Handler, M. and O?Neill, B. and Wilkinson, C. and Governale, L. and Drapeau, A. and Leonard, J. and Sribnick, E. and Shaikhouni, A. and Ahn, E. and Cohen, A. and Groves, M. and Robinson, S. and Bonfield, C.M. and Shannon, C.

DOI: 10.1007/s11060-023-04316-4

Outcomes of a radiation sparing approach in medulloblastoma by subgroup in young children: an institutional review

Child's Nervous System

Ronsley, R. and Triscott, J. and Stanek, J. and Rassekh, S.R. and Lum, A. and Cheng, S. and Goddard, K. and McConnell, D. and Strahlendorf, C. and Singhal, A. and Finlay, J.L. and Yip, S. and Dunham, C. and Hukin, J.

DOI: 10.1007/s00381-023-05918-z

Cosmetic satisfaction and patient-reported outcomes following surgical treatment of single-suture craniosynostosis: a systematic review

Child's Nervous System

Klieverik, V.M. and Singhal, A. and Woerdeman, P.A.

DOI: 10.1007/s00381-023-06063-3

Added value of corpus callosotomy following vagus nerve stimulation in children with Lennox"Gastaut syndrome: A multicenter, multinational study

Epilepsia

Roth, J. and Bergman, L. and Weil, A.G. and Brunette-Clement, T. and Weiner, H.L. and Treiber, J.M. and Shofty, B. and Cukiert, A. and Cukiert, C.M. and Tripathi, M. and Sarat~Chandra, P. and Bollo, R.J. and Machado, H.R. and Santos, M.V. and Gaillard, W.D. and Oluigbo, C.O. and Ibrahim, G.M. and Jallo, G.I. and Shimony, N. and O'Neill, B.R. and Budke, M. and Prez-Jimnez, M.?. and Mangano, F.T. and Iwasaki, M. and Iijima, K. and Gonzalez-Martinez, J. and Kawai, K. and Ishishita, Y. and Elbabaa, S.K. and Bello-Espinosa, L. and Fallah, A. and Maniquis, C.A.B. and Ben-Zvi, I. and Tisdall, M. and Panigrahi, M. and Jayalakshmi, S. and Blount, J.P. and Dorfmller, G. and Bulteau, C. and Stone, S.S. and Bolton, J. and Singhal, A. and Connolly, M. and Alsowat, D. and Alotaibi, F. and Ragheb, J. and Uliel-Sibony, S.

DOI: 10.1111/epi.17796

A qualitative study of transitioning patients with hydrocephalus from pediatric to adult care: fear of uncertainty, communication gaps, independence, and loss of relationships

Journal of Neurosurgery: Pediatrics

Fouladirad, S. and Cheong, A. and Singhal, A. and Tamber, M.S. and McDonald, P.J.

DOI: 10.3171/2022.2.PEDS21419

Treatment-responsive Holmes tremor in a child with low-pressure hydrocephalus: video case report and systematic review of the literature

Journal of Neurosurgery: Pediatrics

Chang, S.J. and Mitchell, R. and Hukin, J. and Singhal, A.

DOI: 10.3171/2021.12.PEDS21539

Acetazolamide to treat symptomatic ruptured arachnoid cysts: illustrative cases

Journal of Neurosurgery: Case Lessons

Watson, I. and McDonald, P.J. and Steinbok, P. and Graeber, B. and Singhal, A.

DOI: 10.3171/CASE21462

Endoscopic third ventriculostomy revision after failure of initial endoscopic third ventriculostomy and choroid plexus cauterization

Journal of Neurosurgery: Pediatrics

Arynchyna-Smith, A. and Rozzelle, C.J. and Jensen, H. and Reeder, R.W. and Kulkarni, A.V. and Pollack, I.F. and Wellons, J.C. and Naftel, R.P. and Jackson, E.M. and Whitehead, W.E. and Pindrik, J.A. and Limbrick, D.D. and McDonald, P.J. and Tamber, M.S. and O'Neill, B.R. and Hauptman, J.S. and Krieger, M.D. and Chu, J. and Simon, T.D. and Riva-Cambrin, J. and Kestle, J.R.W. and Rocque, B.G. and Brockmeyer, D. and Walker, M. and Bollo, R. and Cheshier, S. and Blount, J. and Johnston, J. and Acakpo-Satchivi, L. and Oakes, W.J. and Dirks, P. and Rutka, J. and Taylor, M. and Dirks, P. and Curry, D. and Aldave, G. and Dauser, R. and Jea, A. and Lam, S. and Weiner, H. and Luerssen, T. and Ellenbogen, R. and Ojemann, J. and Lee, A. and Avellino, A. and Greene, S. and Tyler-Kabara, E. and Abel, T. and Park, T.S. and Strahle, J. and McEvoy, S. and Smyth, M. and Tulipan, N. and Singhal, A. and Steinbok, P. and Cochrane, D. and Hader, W. and Gallagher, C. and Benour, M. and Kiehna, E. and McComb, J.G. and Chiarelli, P. and Robison, A. and Alexander, A. and Handler, M. and Hankinson, T. and Wilkinson, C. and Governale, L. and Drapeau, A. and Leonard, J. and Sribnick, E. and Shaikhouni, A. and Ahn, E. and Cohen, A. and Groves, M. and Robinson, S. and Bonfield, C.M. and Shannon, C. and Holman, L. and Clawson, J. and Martello, P. and Tattersall, N. and Bach, T. and Caudill, T. and Komarova, P. and Bey, A. and Ashrafpour, H. and Lamberti-Pasculli, M. and O'Connor, L. and Santisbon, E. and Sanchez, E. and Martinez, S. and Ryan, S. and Hall, K. and Gangan, C. and Klein, J. and Anderson, A. and Bowen, G. and Thambireddy, S. and Diamond, K. and Luther, A. and Morgan, A. and Botteron, H. and Morales, D. and Gabir, M. and Berger, D. and Mercer, D. and Stone, M. and Wiseman, A. and Stoll, J. and Dawson, D. and Gannon, S. and Cheong, A. and Hengel, R. and Rashid, R. and Ahmed, S. and Yea, J. and Loudermilk, A. and Chapman, N. and Rea, N. and Cook, C. and Staulcup, S. and Saraswat, S. and Sheline, A. and Nunn, N. and Langley, M. and Wall, V. and Austin, D. and Conley, B. and Freimann, V. and Herrera, L. and Miller, B.

DOI: 10.3171/2022.3.PEDS224

A case series of pediatric survivors of anaplastic pleomorphic xanthoastrocytoma

Neuro-Oncology Advances

Rebecca Ronsley and Christopher Dunham and Stephen Yip and Lindsay Brown and Jeffrey A Zuccato and Shirin Karimi and Gelareh Zadeh and Karen Goddard and Ash Singhal and Juliette Hukin and Sylvia Cheng

DOI: 10.1093/noajnl/vdaa176

01 / 2021

Cerebellar mutism after posterior fossa tumor resection in children: a multicenter international retrospective study to determine possible modifiable factors

Child's Nervous System

Renne, B. and Radic, J. and Agrawal, D. and Albrecht, B. and Bonfield, C.M. and Cohrs, G. and Davis, T. and Gupta, A. and Hebb, A.L.O. and Lamberti-Pasculli, M. and Knerlich-Lukoschus, F. and Lindsay, S. and McNeely, P.D. and Pillai, S. and Rai, H.I.S. and Sborov, K.D. and Vitali, A. and Walling, S. and Woerdeman, P. and Suryaningtyas, W. and Cochrane, D. and Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-019-04058-7

Systematic review of spinal deformities following multi-level selective dorsal rhizotomy

Child's Nervous System

Wheelwright, M. and Selvey, P.J. and Steinbok, P. and Singhal, A. and Ibrahim, G. and Fallah, A. and Weil, A.G. and Halvorson, K. and Tu, A.

DOI: 10.1007/s00381-019-04375-x

Cranioplasties following craniectomies in children"a multicenter, retrospective cohort study

Child's Nervous System

Klieverik, V.M. and Miller, K.J. and Han, K.S. and Singhal, A. and Vassilyadi, M. and Touchette, C.J. and Weil, A.G. and Woerdeman, P.A.

DOI: 10.1007/s00381-018-4024-2

Cranioplasty after craniectomy in pediatric patients"a systematic review

Child's Nervous System

Klieverik, V.M. and Miller, K.J. and Singhal, A. and Han, K.S. and Woerdeman, P.A.

DOI: 10.1007/s00381-018-4025-1

An Educational Video Improves Consent in Pediatric Lumbar Puncture: A Randomized Control Trial

Pediatric Neurology

Dunbar, M. and Paton, G. and Singhal, A.

DOI: 10.1016/j.pediatrneurol.2019.04.014

The Preferred Attributes of a Trauma Team Leader: Evidence From a Discrete Choice Experiment

Journal of Surgical Education

Mo, D. and O'Hara, N.N. and Hengel, R. and Cheong, A.R. and Singhal, A.

DOI: 10.1016/j.jsurg.2018.06.021

Outcomes and complications for individual neurosurgeons for the treatment of Chiari I malformation at a childrens hospital

Child's Nervous System

Walker-Palmer, T.-K. and Cochrane, D.D. and Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-019-04201-4

What attributes define excellence in a trauma team? A qualitative study

Canadian Journal of Surgery

Kassam, F. and Cheong, A.R. and Evans, D. and Singhal, A.

DOI: 10.1503/cjs.012416

Impact of work hours and sleep on well-being and burnout for physicians-in-training: the Resident Activity Tracker Evaluation Study

Medical Education

Mendelsohn, D. and Despot, I. and Gooderham, P.A. and Singhal, A. and Redekop, G.J. and Toyota, B.D.

DOI: 10.1111/medu.13757

Examining the need for routine intensive care admission after surgical repair of nonsyndromic craniosynostosis: A preliminary analysis

Journal of Neurosurgery: Pediatrics

Bonfield, C.M. and Basem, J. and Cochrane, D.D. and Singhal, A. and Steinbok, P.

DOI: 10.3171/2018.6.PEDS18136

International survey on the management of Chiari 1 malformation and syringomyelia: evolving worldwide opinions

Child's Nervous System

Singhal, A. and Cheong, A. and Steinbok, P.

DOI: 10.1007/s00381-018-3741-x

MRI in mild pediatric traumatic brain injury: Diagnostic overkill or useful tool?

Child's Nervous System

Cohrs, G. and Huhndorf, M. and Niemczyk, N. and Volz, L.J. and Bernsmeier, A. and Singhal, A. and Larsen, N. and Synowitz, M. and Knerlich-Lukoschus, F.

DOI: 10.1007/s00381-018-3771-4

Bobble-head doll syndrome: Report of 2 cases and a review of the literature, with video documentation of the clinical phenomenon

Journal of Neurosurgery: Pediatrics

Renne, B. and Rueckriegel, S. and Ramachandran, S. and Radic, J. and Steinbok, P. and Singhal, A.

DOI: 10.3171/2017.9.PEDS16704

Eight-year outcome of implementation of abusive head trauma prevention

Child Abuse and Neglect

Barr, R.G. and Barr, M. and Rajabali, F. and Humphreys, C. and Pike, I. and Brant, R. and Hlady, J. and Colbourne, M. and Fujiwara, T. and Singhal, A.

DOI: 10.1016/j.chiabu.2018.07.004

Video Diversion Improves Success Rate of Fundoscopic Examination in Children: A Prospective Randomized Controlled Trial

Pediatric Neurology

Yang, M.M.H. and Singhal, A. and Hengel, A.R. and Kerr, J.M. and St-Pierre, G.H. and George, S. and Muir, K. and Thiessen, P. and Enarson, P.

DOI: 10.1016/j.pediatrneurol.2017.09.008

Challenges in minor TBI and indications for head CT in pediatric TBI"an update

Child's Nervous System

Singh, N. and Singhal, A.

DOI: 10.1007/s00381-017-3535-6

Correction to: Challenges in minor TBI and indications for head CT in pediatric TBI"an update (Childs Nerv Syst, (2017), 33,(1677"1681), 10.1007/s00381-017-3535-6)

Child's Nervous System

Singh, N. and Singhal, A.

DOI: 10.1007/s00381-017-3608-6

State of global pediatric neurosurgery outreach: Survey by the International Education Subcommittee

Journal of Neurosurgery: Pediatrics

Davis, M.C. and Rocque, B.G. and Singhal, A. and Ridder, T. and Pattisapu, J.V. and Johnston, J.M.

DOI: 10.3171/2017.3.PEDS16433

Manifestations of Tuberous Sclerosis Complex: The Experience of a Provincial Clinic

Canadian Journal of Neurological Sciences

Wilbur, C. and Sanguansermsri, C. and Chable, H. and Anghelina, M. and Peinhof, S. and Anderson, K. and Steinbok, P. and Singhal, A. and Datta, A. and Connolly, M.B.

DOI: 10.1017/cjn.2016.311

Impact of early follow-up intervention on parent-reported postconcussion pediatric symptoms: A feasibility study

Journal of Head Trauma Rehabilitation

Mortenson, P. and Singhal, A. and Hengel, A.R. and Purtzki, J.

DOI: 10.1097/HTR.0000000000000223

Regression of ventriculomegaly following medical management of a patient with Hurler syndrome

Journal of Neurosurgery: Pediatrics

Liang, J. and Singhal, A.

DOI: 10.3171/2015.9.PEDS15477

Establishing MRI in the acute pediatric mild traumatic brain injury setting

German Medical Science GMS Publishing House

DOI: 10.3205/16DGNC433

Minimizing blood transfusions in the surgical correction of craniosynostosis: a 10-year single-center experience

Child's Nervous System

Bonfield, C.M. and Sharma, J. and Cochrane, D.D. and Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-015-2900-6

Neurosurgery (Pediatric Neurosurgery)

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

MM Yang and A Singhal and N Au and AR Hengel

DOI: 10.1017/cjn.2015.217

05 / 2015

Intraoperative ultrasound in pediatric brain tumors: does the surgeon get it right?

Child's Nervous System

Singhal, A. and Ross Hengel, A. and Steinbok, P. and Doug Cochrane, D.

DOI: 10.1007/s00381-015-2805-4

Intracystic interferon-a treatment leads to neurotoxicity in craniopharyngioma: Case report

Journal of Neurosurgery: Pediatrics

Sharma, J. and Bonfield, C.M. and Singhal, A. and Hukin, J. and Steinbok, P.

DOI: 10.3171/2015.2.PEDS14656

Hypothermia for traumatic brain injury in children - A Phase II randomized controlled trial

Critical Care Medicine

Beca, J. and Mcsharry, B. and Erickson, S. and Yung, M. and Schibler, A. and Slater, A. and Wilkins, B. and Singhal, A. and Williams, G. and Sherring, C. and Butt, W.

DOI: 10.1097/CCM.0000000000000947

Evolution of a Pediatric Primary Cerebral ALK-1-Positive Anaplastic Large Cell Lymphoma on Serial MRI

Pediatric Neurosurgery

Dunbar, M.J. and Singhal, A. and Rassekh, S.R. and Dunham, C.

DOI: 10.1159/000380769

Central nervous system germ cell tumors (CNS-GCT)

Pediatric Neuro-oncology

Bartels, U. and Singhal, A.

DOI: 10.1007/978-1-4939-1541-5

The role of resection alone in select children with intracranial ependymoma: the Canadian Pediatric Brain Tumour Consortium experience

Child's Nervous System

Ailon, T. and Dunham, C. and Carret, A.-S. and Tabori, U. and Mcneely, P.D. and Zelcer, S. and Wilson, B. and Lafay-Cousin, L. and Johnston, D. and Eisenstat, D.D. and Silva, M. and Jabado, N. and Goddard, K.J. and Fryer, C. and Hendson, G. and Hawkins, C. and Dunn, S. and Yip, S. and Singhal, A. and Hukin, J.

DOI: 10.1007/s00381-014-2575-4

Preoperative ultrasound localization of the lambda in patients with scaphocephaly: A technical note for minimally invasive craniectomy

Journal of Neurosurgery: Pediatrics

Bonfield, C.M. and Cochrane, D.D. and Singhal, A. and Steinbok, P.

DOI: 10.3171/2015.5.PEDS15157

Impact of preoperative laboratory investigation and blood cross-match on clinical management of pediatric neurosurgical patients

Child's Nervous System

Yang, M.M.H. and Singhal, A. and Au, N. and Hengel, A.R.

DOI: 10.1007/s00381-015-2617-6

CSF complications following intradural spinal surgeries in children

Child's Nervous System

Liu, V. and Gillis, C. and Cochrane, D. and Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-013-2276-4

Video diversion during fundoscopic examination in children: A randomized controlled trial

Journal of Child Neurology

Singhal, A. and Yang, M.M.H. and Kerr, J.M.

DOI: 10.1177/0883073813483363

Traumatic brain injury and critical care management in the pediatric population

Neurosurgery Knowledge Update (Harbaugh eds)

Singhal A, Hengel AR. Traumatic brain injury and critical care management in the pediatric population. In: Neurosurgery Knowledge Update (Harbaugh eds). Thieme Publishers. New York, 2014. (Submitted for publication).

Neurointensive Care for Head Injuries

Pediatric Neurosurgery Tricks of the Trade (Cohen, A. eds)

Singhal A, Hengel AR. Neurointensive Care for Head Injuries. In: Pediatric Neurosurgery Tricks of the Trade (Cohen, A. eds). Thieme Publishers. New York, 2014.

Neurological morbidity of surgical resection of pediatric cerebellar astrocytomas

Child's Nervous System

Steinbok, P. and Mangat, J.S. and Kerr, J.M. and Sargent, M. and Suryaningtyas, W. and Singhal, A. and Cochrane, D.

DOI: 10.1007/s00381-013-2171-z

Does optic nerve sheath diameter on MRI decrease with clinically improved pediatric hydrocephalus?

Child's Nervous System

Singhal, A. and Yang, M.M.H. and Sargent, M.A. and Cochrane, D.D.

DOI: 10.1007/s00381-012-1937-z

Ring apophysis fracture in pediatric lumbar disc herniation: A common entity

Pediatric Neurosurgery

Singhal, A. and Mitra, A. and Cochrane, D. and Steinbok, P.

DOI: 10.1159/000355127

Bilateral lambdoid and posterior sagittal craniosynostosis - Management, evolution, and outcome

Child's Nervous System

Pillai, S. and Cochrane, D. and Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-013-2155-z

Personalizing the treatment of pediatric medulloblastoma: Polo-like kinase 1 as a molecular target in high-risk children

Cancer Research

Triscott, J. and Lee, C. and Foster, C. and Manoranjan, B. and Pambid, M.R. and Berns, R. and Fotovati, A. and Venugopal, C. and O'Halloran, K. and Narendran, A. and Hawkins, C. and Ramaswamy, V. and Bouffet, E. and Taylor, M.D. and Singhal, A. and Hukin, J. and Rassekh, R. and Yip, S. and Northcott, P. and Singh, S.K. and Dunham, C. and Dunn, S.E.

DOI: 10.1158/0008-5472.CAN-12-4331

Stridor at birth predicts poor outcome in neonates with myelomeningocele

Child's Nervous System

Ocal, E. and Irwin, B. and Cochrane, D. and Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-011-1585-8

Possible differentiation of cerebral glioblastoma into pleomorphic xanthoastrocytoma: An unusual case in an infant - Case report

Journal of Neurosurgery: Pediatrics

Yang, M.M.H. and Singhal, A. and Rassekh, S.R. and Yip, S. and Eydoux, P. and Dunham, C.

DOI: 10.3171/2012.1.PEDS11326

Endoscopic fenestration of cavum velum interpositum cysts: A case study of two symptomatic patients

Child's Nervous System

Tong, C.K.W. and Singhal, A. and Cochrane, D.D.

DOI: 10.1007/s00381-012-1770-4

Polo-like kinase 1 inhibition kills glioblastoma multiforme brain tumor cells in part through loss of SOX2 and delays tumor progression in mice

Stem Cells

Lee, C. and Fotovati, A. and Triscott, J. and Chen, J. and Venugopal, C. and Singhal, A. and Dunham, C. and Kerr, J.M. and Verreault, M. and Yip, S. and Wakimoto, H. and Jones, C. and Jayanthan, A. and Narendran, A. and Singh, S.K. and Dunn, S.E.

DOI: 10.1002/stem.1081

Improper use of child restraint seats as a sleeping environment: Two cases of childhood death

Paediatrics and Child Health (Canada)

Singhal, A. and Adams, E. and Desapriya, E.

DOI: 10.1093/pch/17.9.498

Consensus definitions of complications for accurate recording and comparisons of surgical outcomes in pediatric neurosurgery: Clinical article

Journal of Neurosurgery: Pediatrics

Drake, J.M. and Singhal, A. and Kulkarni, A.V. and DeVeber, G. and Cochrane, D.D.

DOI: 10.3171/2012.3.PEDS11233

Pediatric patients with poor neurological status and arteriovenous malformation hemorrhage: An outcome analysis: Clinical article

Journal of Neurosurgery: Pediatrics

Singhal, A. and Adirim, T. and Cochrane, D. and Steinbok, P.

DOI: 10.3171/2011.2.PEDS10355

Trends in paediatric sport- and recreation-related injuries: An injury surveillance study at the British Columbia Children's Hospital (Vancouver, British Columbia) from 1992 to 2005

Paediatrics and Child Health

Pakzad-Vaezi, K. and Singhal, A.

DOI: 10.1093/pch/16.4.217

Third ventricular shape: A predictor of endoscopic third ventriculostomy success in pediatric patients. Clinical article

Journal of Neurosurgery: Pediatrics

Foroughi, M. and Wong, A. and Steinbok, P. and Singhal, A.S.H. and Sargent, M.A. and Cochrane, D.D.

DOI: 10.3171/2011.1.PEDS10461

Natural history of untreated syringomyelia in pediatric patients

Neurosurgical Focus

Singhal, A. and Bowen-Roberts, T. and Steinbok, P. and Cochrane, D. and Byrne, A.T. and Kerr, J.M.

DOI: 10.3171/2011.9.FOCUS11208

Diffusion-weighted imaging and pathological correlation in pediatric medulloblastomas-They are not always restricted!

Child's Nervous System

Pillai, S. and Singhal, A. and Byrne, A.T. and Dunham, C. and Douglas Cochrane, D. and Steinbok, P.

DOI: 10.1007/s00381-011-1499-5

Genetic-environmental interaction in a unique case of Muenke syndrome with intracranial hypertension

Child's Nervous System

Agochukwu, N.B. and Solomon, B.D. and Zajaczkowska-Kielska, A. and Lyons, C.J. and Pollock, T. and Singhal, A. and Van Allen, M.I. and Muenke, M.

DOI: 10.1007/s00381-011-1595-6

Trauma association of canada pediatric subcommittee National pediatric cervical spine evaluation pathway: Consensus guidelines

Journal of Trauma - Injury, Infection and Critical Care

Chung, S. and Mikrogianakis, A. and Wales, P.W. and Dirks, P. and Shroff, M. and Singhal, A. and Grant, V. and Hancock, B.J. and Creery, D. and Atkinson, J. and St-Vil, D. and Crevier, L. and Yanchar, N. and Hayashi, A. and Mehta, V. and Carey, T. and Dhanani, S. and Siemens, R. and Singh, S. and Price, D.

DOI: 10.1097/TA.0b013e3182108823

Conventional and diffusion-weighted magnetic resonance imaging findings in a pediatric patient with a posterior fossa brain tumor and papilledema

Pediatric Neurosurgery

Pakzad-Vaezi, K. and Cochrane, D. and Sargent, M. and Singhal, A.

DOI: 10.1159/000270156

Iatrogenic complications following shunting the subarachnoid space in infancy

Cerebrospinal Fluid Research

Douglas Cochrane and Ryan Janicki and Keith Aronyk and Jeff Pugh and Paul Steinbok and Ash Singhal

DOI: 10.1186/1743-8454-7-s1-s13

Ventriculoperitoneal shunt after previous endoscopic third ventriculostomy: does ETV improve shunt survival?

Cerebrospinal Fluid Research

Ash Singhal and Tia Liu and Doug Cochrane and Paul Steinbok

DOI: 10.1186/1743-8454-7-s1-s14

Supratentorial primitive neuroectodermal tumors

Oncology of CNS Tumors

Singhal, A. and Gul, S. and Steinbok, P.

DOI: 10.1007/978-3-642-02874-8_37

Intracranial hypertension secondary to sigmoid sinus compression by group A streptococcal epidural abscess

Journal of Laryngology and Otology

Ludemann, J.P. and Poskitt, K. and Singhal, A.

DOI: 10.1017/S0022215109990764

Cingulate lesions presenting with epileptic spasms

Journal of Clinical Neurophysiology

Schrader, D. and Langill, L. and Singhal, A. and Steinbok, P. and Connolly, M.B.

DOI: 10.1097/WNP.0b013e3181baaacf

Optic nerve sheath fenestration and bilateral expansile cranioplasty for raised intracranial pressure in craniometaphyseal dysplasia: A case report

Child's Nervous System

Singhal, A. and Cochrane, D.D.

DOI: 10.1007/s00381-007-0549-5

Operative management of growing skull fractures: A technical note

Child's Nervous System

Singhal, A. and Steinbok, P.

DOI: 10.1007/s00381-007-0552-x

Cerebrospinal fluid (CSF) leak and pseudomeningocele formation after posterior fossa tumor resection in children: A retrospective analysis

Child's Nervous System

Steinbok, P. and Singhal, A. and Mills, J. and Cochrane, D.D. and Price, A.V.

DOI: 10.1007/s00381-006-0234-0

Ascites and abdominal pseudocysts following ventriculoperitoneal shunt surgery: Variations of the same theme

Journal of Neurosurgery

Kariyattil, R. and Steinbok, P. and Singhal, A. and Cochrane, D.D.

DOI: 10.3171/ped.2007.106.5.350

Long-term outcome of infants with positional occipital plagiocephaly

Child's Nervous System

Steinbok, P. and Lam, D. and Singh, S. and Mortenson, P.A. and Singhal, A.

DOI: 10.1007/s00381-007-0373-y

Early hypodensity on computed tomographic scan of the brain in an accidental pediatric head injury

Neurosurgery

Steinbok, P. and Singhal, A. and Poskitt, K. and Cochrane, D.D.

DOI: 10.1227/01.NEU.0000255398.00410.6B

Analysis of paediatric injuries related to child restraint seats: Are children at higher risk of injury outside the vehicle than inside?

International Journal of Injury Control and Safety Promotion

Desapriya, E.B.R. and Pike, I. and Singhal, A.

DOI: 10.1080/17457300701577252

Gyriform differentiation in medulloblastoma - A radiological predictor of histology

Pediatric Neurosurgery

Agrawal, D. and Singhal, A. and Hendson, G. and Durity, F.A.

DOI: 10.1159/000098390

Complete upward migration of the peritoneal end of a ventriculoperitoneal shunt into the subgaleal space

Pediatric Neurosurgery

Gan, P.Y.C. and Singhal, A.

DOI: 10.1159/000095575

Scalp Ulceration From a Circumferential Head Dressing After Craniotomy: Case Report of An Uncommon Complication Due to Human Error

Canadian Journal of Plastic Surgery

Ashutosh Singhal and Peter W Bray and Mark Bernstein

DOI: 10.1177/229255030401200408

Surgical Management of Spinal Metastatic Disease

Youmans Neurological Surgery, 5th edition (Winn, H.R. eds)

Singhal A, Perrin RG. Surgical Management of Spinal Metastatic Disease. In: Youmans Neurological Surgery, 5th edition (Winn, H.R. eds). WB Saunders, Philadelphia PA, 2004.

Trauma recidivism in a large urban Canadian population

Journal of Trauma - Injury, Infection and Critical Care

Caufeild, J. and Singhal, A. and Moulton, R. and Brenneman, F. and Redelmeier, D. and Baker, A.J.

DOI: 10.1097/01.TA.0000135350.06670.60

Neuroendoscopic basket dilation technique for the fenestration of the ventricular wall or intracranial cysts - Technical note: Commentary

Neurologia Medico-Chirurgica

Arai, H. and Miyajima, M. and Singhal, A. and Rutka, J.T.

An Acute CNS Inflammatory Response Correlates with Outcome in Human Traumatic Brain Injury

Journal of Neurotrauma

Singhal A, Reinders FX, Moulton RJ, Baker AJ. An Acute CNS Inflammatory Response Correlates with Outcome in Human Traumatic Brain Injury. J Neurotrauma 2002 Aug;19(8):929-37

08 / 2002

Association between cerebrospinal fluid interleukin-6 concentrations and outcome after severe human traumatic brain injury

Journal of Neurotrauma

Singhal, A. and Baker, A.J. and Hare, G.M.T. and Reinders, F.X. and Schlichter, L.C. and Moulton, R.J.

DOI: 10.1089/089771502320317087

Intensive Care Unit Management of Spinal Cord Injury

Intensive Care in Neurosurgery (Andrews, B, eds)

Singhal A, Baker, A, Fehlings, MG: Intensive Care Unit Management of Spinal Cord Injury. In: Intensive Care in Neurosurgery (Andrews, B, eds). AANS Publication Series, New York 2002: pp 137-143.

Outpatient lumbar microdiscectomy: A prospective study in 122 patients

Canadian Journal of Neurological Sciences

Singhal, A. and Bernstein, M.

DOI: 10.1017/S031716710000202X

Near nerve local insulin prevents conduction slowing in experimental diabetes

Brain Research

Ash Singhal and Chu Cheng and Hong Sun and Douglas W Zochodne

DOI: 10.1016/s0006-8993(97)00412-5

07 / 1997

Possible Trophic Actions of Near-Nerve Insulin in Diabetic and Nondiabetic Rats

Neurology

Singhal A, Sun H, Cheng C, Zochodne DW. Possible Trophic Actions of Near-Nerve Insulin in Diabetic and Nondiabetic Rats. Neurology 1996;46(2): 396-397

Apolipoprotein E and Pediatric Traumatic Brain Injury: A Prospective Observational Study

Traumatic Brain Injury (TBI) is a particularly significant public health issue in children and adolescents, who account for over 50 per cent of new cases of head injury yearly. The causes for this are multi-factorial, but recent studies in adult TBI suggest that a genetic marker, the APOE gene, may play a role in influencing outcomes. We aim to determine if there is a relationship between subtypes of a gene encoding a lipoprotein, Apolipoprotein E, and outcome after pediatric TBI. Our hypothesis is that a genetic allelic subtype, APOE4, is associated with worse outcomes. Children with apparently similar demographic characteristics, mechanism of injury, and apparently similar clinical and radiographic injury patterns have notably different clinical outcomes.

BC Inflicted Childhood Neurotrauma Surveillance Project

The BC Inflicted Childhood Neurotrauma Surveillance Project is a part of Phase II of Preventing Shaken Baby Syndrome and Infant Abuse: The Period of PURPLE Crying Program. It is an active surveillance project that documents traumatic head injury in children less than two years of age.

The Program will be evaluated for its effectiveness in attaining the three primary goals of the intervention:

Attaining a “penetration” rate of 90-95 per cent of mothers of newborn infants
Reducing the incidence of shaken baby syndrome and/or infant abuse by 50 per cent
Achieving a cultural change in the understanding of early infant crying and its relationship to shaken baby syndrome
The surveillance system will also address the crucial need in B.C, for current knowledge of ICN incidence, as well as the challenges of measuring and implications for assessing prevention interventions. The first of its kind in Canada, this system will allow the establishment of a baseline incidence of ICN in B.C. Other objectives include determining the proportion of ICN versus non-inflicted neurotrauma and comparing the key characteristics of children with ICN to those with non-inflicted neurotrauma, and to the population at risk in the age group of 0-2 years old.

Analysis of Pediatric Injuries Related to Child Restraint Seats: Are Children at Higher Risk for Injury Outside the Vehicle Than Inside?

With the increasing popularity of hand-held child restraint seats (CRS), BC Children's Hospital clinicians have noticed an increase in injuries related to the improper use of CRS when used outside of the vehicle. These injuries include falls out of the CRS or falls of both the CRS and child. This potential public heath problem has not previously been studied.

We propose to study the problem on a national basis via coordinated data collection/retrieval in the pediatric trauma centers across the country. By examining pediatric trauma in cases in which a CRS was involved, we might identify what the national incidence and contributing factors of such injuries are. Furthermore, we also hope to determine the anatomical pattern of injury associated with CRS injuries, particularly when associated with improper use of the seat outside the vehicle.

Honours & Awards

Ontario Graduate Scholarship in Science and Techn. Research Award – University of Toronto, 2001

Critical Care Research Award – Canadian Congress of Neurological Sciences, 2003

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