Overview

My interests are in clinical research in pediatric oncology. I am interested specific oncologic diseases (renal tumours, histiocytic disorders) as well as supportive care issues in pediatric oncology patients. I am also interested in the psychosocial impact on patients and families within this population.

Publications

Adenovirus Infection in Children With Acute Myeloid LeukemiaA Report From the Canadian Infection in Acute Myeloid Leukemia Research Group
The Pediatric Infectious Disease Journal
Samuele Renzi, Salah Ali, Carol Portwine, David Mitchell, David Dix, Victor Lewis, Victoria Price, Michelle Science, Lillian Sung
DOI: 10.1097/inf.0000000000001723
02/2018

Most children with cancer are not enrolled on a clinical trial in Canada: a population-based study
BMC Cancer
Jason D. Pole, Randy Barber, Rose-Émilie Bergeron, Anne Sophie Carret, David Dix, Ketan Kulkarni, Emilie Martineau, Alicia Randall, David Stammers, Caron Strahlendorf, Douglas R. Strother, Tony H. Truong, Lillian Sung
DOI: 10.1186/s12885-017-3390-6
06/2017

Validation of the Symptom Screening in Pediatrics Tool in Children Receiving Cancer Treatments
JNCI: Journal of the National Cancer Institute
L Lee Dupuis, Donna L Johnston, Christina Baggott, Shannon Hyslop, Deborah Tomlinson, Paul Gibson, Andrea Orsey, David Dix, Vicky Price, Magimairajan Vanan, Carol Portwine, Susan Kuczynski, Brenda Spiegler, George A Tomlinson, Lillian Sung
DOI: 10.1093/jnci/djx250
2017

Successful umbilical cord blood hematopoietic stem cell transplantation in pediatric patients with MDS/AML associated with underlying GATA2 mutations: two case reports and review of literature.
Pediatric transplantation
Mallhi K, Dix DB, Niederhoffer KY, Armstrong L, Rozmus J
DOI: 10.1111/petr.12764
PubMed: 27416790
11/2016

Quality of life of pediatric oncology patients: Do patient-reported outcome instruments measure what matters to patients?
Quality of Life Research
Samantha J. Anthony, Enid Selkirk, Lillian Sung, Robert J. Klaassen, David Dix, Anne F. Klassen
DOI: 10.1007/s11136-016-1393-4
08/2016

Invasive Rothia infections in children with acute myeloid leukemia: A report from the Canadian infections in AML research group
Pediatric Hematology and Oncology
Jane Y. Wang, Josée Brossard, Sonia Cellot, David Dix, Jim Feusner, Donna L. Johnston, Victor Lewis, David Mitchell, Carol Portwine, Victoria Price, Lillian Sung, Marie-Chantal Ethier, Biljana Gillmeister
DOI: 10.1080/08880018.2016.1187231
06/2016

Single nucleotide polymorphism in IL1B is associated with infection risk in paediatric acute myeloid leukaemia
Clinical Microbiology and Infection
L. Sung, D. Dix, S. Cellot, B. Gillmeister, M.C. Ethier, N.M. Roslin, D.L. Johnston, J. Feusner, D. Mitchell, V. Lewis, R. Aplenc, R. Yanofsky, C. Portwine, V. Price, S. Zelcer, M. Silva, L. Bowes, B. Michon, K. Stobart, J. Traubici, U. Allen, J. Beyene, N. den Hollander, A.D. Paterson
DOI: 10.1016/j.cmi.2016.02.006
06/2016

The development of scales to measure childhood cancer survivors' readiness for transition to long-term follow-up care as adults.
Health expectations : an international journal of public participation in health care and health policy
Klassen AF, Rosenberg-Yunger ZR, D'Agostino NM, Cano SJ, Barr R, Syed I, Granek L, Greenberg ML, Dix D, Nathan PC
DOI: 10.1111/hex.12241
PubMed: 25052198
12/2015

Management and Outcome of Patients With Langerhans Cell Histiocytosis and Single-Bone CNS-Risk Lesions: A Multi-Institutional Retrospective Study.
Pediatric blood & cancer
Chellapandian D, Shaikh F, van den Bos C, Somers GR, Astigarraga I, Jubran R, Degar B, Carret AS, Mandel K, Belletrutti M, Dix D, Visser J, Abla O
DOI: 10.1002/pbc.25645
PubMed: 26179251
12/2015

Impact of registration on clinical trials on infection risk in pediatric acute myeloid leukemiaTrial registration and infection risk
International Journal of Cancer
David Dix, Richard Aplenc, Lynette Bowes, Sonia Cellot, Marie-Chantal Ethier, Jim Feusner, Biljana Gillmeister, Donna L. Johnston, Victor Lewis, Bruno Michon, David Mitchell, Carol Portwine, Victoria Price, Mariana Silva, Kent Stobart, Rochelle Yanofsky, Shayna Zelcer, Joseph Beyene, Lillian Sung
DOI: 10.1002/ijc.29905
11/2015

MG-116 Report of 2 families with emberger syndrome (GATA2 mutation): Recognition of variance in clinical phenotype allows detection prior to malignant presentation
Journal of Medical Genetics
Karen Y Niederhoffer, David Dix, Wingfield Rehmus, Barbara McGillivray, Linlea Armstrong
DOI: 10.1136/jmedgenet-2015-103577.9
11/2015

Factors associated with childhood cancer survivors’ knowledge about their diagnosis, treatment, and risk for late effects
Journal of Cancer Survivorship
Iqra A. Syed, Anne F. Klassen, Ronald Barr, Rebecca Wang, David Dix, Marion Nelson, Zahava R. S. Rosenberg-Yunger, Paul C. Nathan
DOI: 10.1007/s11764-015-0482-7
09/2015

Brain Abscesses Due to Aspergillus nidulans Infection During Induction Chemotherapy for Acute Lymphoblastic Leukemia
Journal of Pediatric Hematology/Oncology
Manish Sadarangani, Melissa Harvey, Allison McDonald, David P. Speert, David Dix
DOI: 10.1097/mph.0000000000000351
08/2015

The pediatric hematology/oncology educational laboratory in-training examination (PHOELIX): A formative evaluation of laboratory skills for Canadian pediatric hematology/oncology traineesLaboratory In-Training Examination
Pediatric Blood & Cancer
Elaine Leung, David Dix, Jason Ford, Dorothy Barnard, Eileen McBride
DOI: 10.1002/pbc.25613
07/2015

Non-operative management of suspected solitary calvarial Langerhans cell histiocytosis in children
Pediatric Blood & Cancer
05/2015

Survey of Langerhans Cell Histiocytosis in Canada
Pediatric Blood & Cancer
05/2015

A randomized, double-blind, placebo-controlled clinical trial of megestrol acetate as an appetite stimulant in children with weight loss due to cancer and/or cancer therapy.
Pediatric blood & cancer
Cuvelier GD, Baker TJ, Peddie EF, Casey LM, Lambert PJ, Distefano DS, Wardle MG, Mychajlunow BA, Romanick MA, Dix DB, Wilson BA
DOI: 10.1002/pbc.24828
PubMed: 24167059
04/2014

Predictors and Outcomes of Viridans Group Streptococcal Infections in Pediatric Acute Myeloid LeukemiaFrom the Canadian Infections in AML Research Group
The Pediatric Infectious Disease Journal
Victor Lewis, Rochelle Yanofsky, David Mitchell, David Dix, Marie-Chantal Ethier, Biljana Gillmeister, Donna Johnston, Bruno Michon, Kent Stobart, Carol Portwine, Mariana Silva, Sonia Cellot, Victoria Price, Lynette Bowes, Shayna Zelcer, Josee Brossard, Joseph Beyene, Lillian Sung
DOI: 10.1097/inf.0000000000000058
02/2014

Second Bacteremia During Antibiotic Treatment in Children With Acute Myeloid Leukemia: A Report From the Canadian Infections in Acute Myeloid Leukemia Research Group
Journal of the Pediatric Infectious Diseases Society
T. H. Tran, R. Yanofsky, D. L. Johnston, D. Dix, B. Gillmeister, M.-C. Ethier, C. Portwine, V. Price, D. Mitchell, S. Cellot, V. Lewis, S. Zelcer, M. Silva, B. Michon, L. Bowes, K. Stobart, J. Brossard, J. Beyene, L. Sung
DOI: 10.1093/jpids/pit086
01/2014

Is the Give Youth a Voice questionnaire an appropriate measure of teen-centred care in paediatric oncology: a Rasch measurement theory analysis
Health Expectations
Anne F Klassen, Stefan J. Cano, Roona Sinha, Areej Shahbaz, Robert Klaassen, David Dix
DOI: 10.1111/hex.12161
11/2013

Understanding the healthcare experiences of teenaged cancer patients and survivorsHealthcare experiences of teenaged cancer patients
Child: Care, Health and Development
G. Farjou, R. Sinha, D. Dix, A. Shahbaz, R. J. Klaassen, A. F. Klassen
DOI: 10.1111/cch.12109
10/2013

Considering quality of life for children with cancer: a systematic review of patient-reported outcome measures and the development of a conceptual model
Quality of Life Research
Samantha J. Anthony, Enid Selkirk, Lillian Sung, Robert J. Klaassen, David Dix, Katrin Scheinemann, Anne F. Klassen
DOI: 10.1007/s11136-013-0482-x
08/2013

A Phase II, prospectively randomized double-blind placebo-controlled trial of megestrol acetate as an appetite stimulant for pediatric cancer-associated malnutrition
Pediatric Blood & Cancer
06/2013

Children's Oncology Group's 2013 blueprint for research: renal tumors.
Pediatric blood & cancer
Dome JS, Fernandez CV, Mullen EA, Kalapurakal JA, Geller JI, Huff V, Gratias EJ, Dix DB, Ehrlich PF, Khanna G, Malogolowkin MH, Anderson JR, COG Renal Tumors Committee
DOI: 10.1002/pbc.24419
PubMed: 23255438
06/2013

Infections in pediatric acute promyelocytic leukemia: from the canadian infections in acute myeloid leukemia research group
BMC Cancer
Sonia Cellot, Donna Johnston, David Dix, Marie-Chantal Ethier, Biljana Gillmeister, David Mitchell, Rochelle Yanofsky, Victor Lewis, Carol Portwine, Victoria Price, Shayna Zelcer, Mariana Silva, Lynette Bowes, Bruno Michon, Kent Stobart, Josee Brossard, Joseph Beyene, Lillian Sung
DOI: 10.1186/1471-2407-13-276
06/2013

Clostridium difficile Infection in Pediatric Acute Myeloid LeukemiaFrom The Canadian Infections in Acute Myeloid Leukemia Research Group
The Pediatric Infectious Disease Journal
Victoria Price, Carol Portwine, Shayna Zelcer, Marie-Chantal Ethier, Biljana Gillmeister, Mariana Silva, Christina Schindera, Rochelle Yanofsky, David Mitchell, Donna L. Johnston, Victor Lewis, David Dix, Sonia Cellot, Bruno Michon, Lynette Bowes, Kent Stobart, Josee Brossard, Joseph Beyene, Lillian Sung
DOI: 10.1097/inf.0b013e31828690a4
06/2013

Infectious Events Prior to Chemotherapy Initiation in Children with Acute Myeloid Leukemia
PLoS ONE
Carol Portwine, David Mitchell, Donna Johnston, Biljana Gillmeister, Marie-Chantal Ethier, Rochelle Yanofsky, David Dix, Sonia Cellot, Victor Lewis, Victoria Price, Mariana Silva, Shayna Zelcer, Lynette Bowes, Bruno Michon, Kent Stobart, Josee Brossard, Joseph Beyene, Lillian Sung
DOI: 10.1371/journal.pone.0061899
04/2013

Invasive fungal infections in paediatric acute myeloid leukaemia
Mycoses
D. L. Johnston, V. Lewis, R. Yanofsky, B. Gillmeister, M. C. Ethier, D. Mitchell, S. Cellot, D. Dix, C. Portwine, V. Price, M. Silva, S. Zelcer, B. Michon, L. Bowes, K. Stobart, J. Brossard, J. Beyene, L. Sung
DOI: 10.1111/myc.12063
02/2013

Single-Parent Caregivers of Children with CancerFactors Assisting With Caregiving Strains
Journal of Pediatric Oncology Nursing
Zahava R. S. Rosenberg-Yunger, Leeat Granek, Lillian Sung, Robert Klaassen, David Dix, John Cairney, Anne F. Klassen
DOI: 10.1177/1043454212471727
01/2013

Infections in children with down syndrome and acute myeloid leukemia: a report from the Canadian infections in AML research group
Infectious Agents and Cancer
Thai Tran, David Mitchell, David Dix, Sonia Cellot, Marie-Chantal Ethier, Biljana Gillmeister, Johann Hitzler, Victor Lewis, Rochelle Yanofsky, Donna L Johnston, Carol Portwine, Victoria Price, Shayna Zelcer, Mariana Silva, Bruno Michon, Lynette Bowes, Kent Stobart, Josee Brossard, Joseph Beyene, Lillian Sung
DOI: 10.1186/1750-9378-8-47
2013

Teen-centred care is associated with type of care and health-related quality of life in adolescent oncology patients
Pediatric Blood & Cancer
12/2012

Caregiving, single parents and cumulative stresses when caring for a child with cancerCaregiving, single parents and cumulative stresses
Child: Care, Health and Development
L. Granek, Z. R. S. Rosenberg-Yunger, D. Dix, R. J. Klaassen, L. Sung, J. Cairney, A. F. Klassen
DOI: 10.1111/cch.12008
11/2012

Rasch analysis of the PedsQL: an increased understanding of the properties of a rating scale
Journal of Clinical Epidemiology
Leila Amin, Peter Rosenbaum, Ronald Barr, Lillian Sung, Robert J. Klaassen, David B. Dix, Anne Klassen
DOI: 10.1016/j.jclinepi.2012.04.014
10/2012

Vitamin B(12) deficiency in infants secondary to maternal causes.
CMAJ : Canadian Medical Association Journal
Roumeliotis N, Dix D, Lipson A
DOI: 10.1503/cmaj.112170
PubMed: 22711730
10/2012

Association Between Corticosteroids and Infection, Sepsis, and Infectious Death in Pediatric Acute Myeloid Leukemia (AML): Results From the Canadian Infections in AML Research Group
Clinical Infectious Diseases
David Dix, Sonia Cellot, Victoria Price, Biljana Gillmeister, Marie-Chantal Ethier, Donna L. Johnston, Victor Lewis, Bruno Michon, David Mitchell, Kent Stobart, Rochelle Yanofsky, Carol Portwine, Mariana Silva, Lynette Bowes, Shayna Zelcer, Josée Brossard, Jeffrey Traubici, Upton Allen, Joseph Beyene, Lillian Sung
DOI: 10.1093/cid/cis774
09/2012

High incidence of vertebral fractures in children with acute lymphoblastic leukemia 12 months after the initiation of therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Alos N, Grant RM, Ramsay T, Halton J, Cummings EA, Miettunen PM, Abish S, Atkinson S, Barr R, Cabral DA, Cairney E, Couch R, Dix DB, Fernandez CV, Ward LM
DOI: 10.1200/jco.2011.40.4830
PubMed: 22734031
08/2012

Demands and Rewards Associated With Working in Pediatric OncologyA Qualitative Study of Canadian Health Care Providers
Journal of Pediatric Hematology / Oncology
David Dix, Sonia Gulati, Paula Robinson, Iqra Syed, Anne Klassen
DOI: 10.1097/mph.0b013e3182580a90
08/2012

The use of parenteral nutrition for the management of PKU patient undergoing chemotherapy for lymphoma: A case report
Molecular Genetics and Metabolism
R. Salvarinova-Zivkovic, C. Hartnett, G. Sinclair, D. Dix, G. Horvath, Y. Lillquist, S. Stockler-Ipsiroglu
DOI: 10.1016/j.ymgme.2012.01.007
04/2012

Multiple Persistent Ganglioneuromas Likely Arising From the Spontaneous Maturation of Metastatic Neuroblastoma
Journal of Pediatric Hematology/Oncology
Jacob Rozmus, Monica Langer, James J. Murphy, David Dix
DOI: 10.1097/mph.0b013e318221ca82
03/2012

Health Care Providers’ Perspectives About Working With Parents of Children With CancerA Qualitative Study
Journal of Pediatric Oncology Nursing
Anne Klassen, Sonia Gulati, David Dix
DOI: 10.1177/1043454212438405
03/2012

Pandemic (H1N1) 2009 influenza in Canadian pediatric cancer and hematopoietic stem cell transplant patientsPandemic H1N1 influenza in pediatric cancer
Influenza and Other Respiratory Viruses
Dat Tran, Michelle Science, David Dix, Carol Portwine, Shayna Zelcer, Donna L. Johnston, Rochelle Yanofsky, Adam Gassas, Marie-Chantal Ethier, Lillian Sung
DOI: 10.1111/j.1750-2659.2012.00352.x
03/2012

Establishing content validity of the Give Youth a Voice Questionnaire for use in Pediatric Oncology: A qualitative study
Quality of Life Research
01/2012

Family-centred care: a qualitative study of Chinese and South Asian immigrant parents' experiences of care in paediatric oncologyImmigrant parents' experiences of care
Child: Care, Health and Development
L. Watt, D. Dix, S. Gulati, L. Sung, R. J. Klaassen, N. T. Shaw, A. F. Klassen
DOI: 10.1111/j.1365-2214.2011.01342.x
11/2011

Understanding the health impact of caregiving: a qualitative study of immigrant parents and single parents of children with cancer
Quality of Life Research
Anne F. Klassen, Sonia Gulati, Leeat Granek, Zahava R. S. Rosenberg-Yunger, Lisa Watt, Lillian Sung, Robert Klaassen, David Dix, Nicola T. Shaw
DOI: 10.1007/s11136-011-0072-8
11/2011

Incidence of vertebral fractures in children after 12 months of chemotherapy
Pediatric Blood & Cancer
11/2011

Cultural Beliefs and Coping Strategies Related to Childhood CancerThe Perceptions of South Asian Immigrant Parents in Canada
Journal of Pediatric Oncology Nursing
Ananya Tina Banerjee, Lisa Watt, Sonia Gulati, Lillian Sung, David Dix, Robert Klassen, Anne F. Klassen
DOI: 10.1177/1043454211408106
05/2011

Immigrant to Canada, newcomer to childhood cancer: a qualitative study of challenges faced by immigrant parents
Psycho-Oncology
Anne F. Klassen, Sonia Gulati, Lisa Watt, Ananya T. Banerjee, Lillian Sung, Robert J. Klaassen, David Dix, Iraj M. Poureslami, Nicola Shaw
DOI: 10.1002/pon.1963
03/2011

Communication and language challenges experienced by Chinese and South Asian immigrant parents of children with cancer in Canada: Implications for health services deliveryImmigrant Parents of Children With Cancer
Pediatric Blood & Cancer
Sonia Gulati, Lisa Watt, Nicola Shaw, Lillian Sung, Iraj M. Poureslami, Robert Klaassen, David Dix, Anne F. Klassen
DOI: 10.1002/pbc.23054
03/2011

Perceptions about complementary and alternative medicine use among Chinese immigrant parents of children with cancer
Supportive Care in Cancer
Lisa Watt, Sonia Gulati, Nicola T. Shaw, Lillian Sung, David Dix, Iraj Poureslami, Anne F. Klassen
DOI: 10.1007/s00520-010-1063-y
02/2011

Red Blood Cell Morphology ReportingHow Much is a Waste of Time?
Journal of Pediatric Hematology/Oncology
Jason C. Ford, Ruth Milner, David B. Dix
DOI: 10.1097/mph.0b013e3181fd6c8b
01/2011

Impact of caring for a child with cancer on single parents compared with parents from two-parent families
Pediatric Blood & Cancer
Anne F. Klassen, David Dix, Michael Papsdorf, Robert J. Klaassen, Rochelle Yanofsky, Lillian Sung
DOI: 10.1002/pbc.22952
01/2011

Caregiving Demands in Parents of Children With Cancer: Psychometric Validation of the Care of My Child With Cancer Questionnaire
Journal of Pediatric Nursing
Anne Klassen, Robert J. Klaassen, David Dix, Sheila Pritchard, Rochelle Yanofsky, Lillian Sung
DOI: 10.1016/j.pedn.2009.01.002
08/2010

Quality of life during active treatment for pediatric acute lymphoblastic leukemiaQuality of Life in Acute Lymphoblastic Leukemia
International Journal of Cancer
Lillian Sung, Rochelle Yanofsky, Robert J. Klaassen, David Dix, Sheila Pritchard, Naomi Winick, Sarah Alexander, Anne Klassen
DOI: 10.1002/ijc.25433
05/2010

Exploring predictors of optimism among parents of children with cancer
Psycho-Oncology
Nora Fayed, Anne F. Klassen, David Dix, Robert Klaassen, Lillian Sung
DOI: 10.1002/pon.1743
04/2010

Parents of children with cancer: Which factors explain differences in health-related quality of life
International Journal of Cancer
Anne F. Klassen, Parminder Raina, Cameron McIntosh, Lillian Sung, Robert J. Klaassen, Maureen O'Donnell, Rochelle Yanofsky, David Dix
DOI: 10.1002/ijc.25737
2010

Establishing a conference for a small program
Medical Teacher
12/2009

The impact of prophylactic fresh-frozen plasma and cryoprecipitate on the incidence of central nervous system thrombosis and hemorrhage in children with acute lymphoblastic leukemia receiving asparaginase
Blood
L. S. Abbott, M. Deevska, C. V. Fernandez, D. Dix, V. E. Price, H. Wang, L. Parker, M. Yhap, C. Fitzgerald, D. R. Barnard, J. N. Berman
DOI: 10.1182/blood-2009-07-231084
10/2009

Advanced Vertebral Fracture Among Newly Diagnosed Children With Acute Lymphoblastic Leukemia: Results of the Canadian Steroid-Associated Osteoporosis in the Pediatric Population (STOPP) Research Program
Journal of Bone and Mineral Research
Jacqueline Halton, Isabelle Gaboury, Ronald Grant, Nathalie Alos, Elizabeth A Cummings, Maryann Matzinger, Nazih Shenouda, Brian Lentle, Sharon Abish, Stephanie Atkinson, Elizabeth Cairney, David Dix, Sara Israels, David Stephure, Beverly Wilson, John Hay, David Moher, Frank Rauch, Kerry Siminoski, Leanne M Ward, and the Canadian STOPP Consortium
DOI: 10.1359/jbmr.090202
07/2009

Parental optimism in poor prognosis pediatric cancers
Psycho-Oncology
Lillian Sung, Robert J. Klaassen, David Dix, Sheila Pritchard, Rochelle Yanofsky, Marie-Chantel Ethier, Anne Klassen
DOI: 10.1002/pon.1490
07/2009

Evaluating family-centred service in paediatric oncology with the measure of processes of care (MPOC-20)
Child: Care, Health and Development
A. F. Klassen, D. Dix, S. J. Cano, M. Papsdorf, L. Sung, R. J. Klaassen
DOI: 10.1111/j.1365-2214.2008.00887.x
01/2009

Factors affecting the delivery of family-centered care in pediatric oncology
Pediatric Blood & Cancer
David B. Dix, Anne F. Klassen, Michael Papsdorf, Robert J. Klaassen, Sheila Pritchard, Lillian Sung
DOI: 10.1002/pbc.22168
2009

Case 2: A pale infant - not a typical case of iron deficiency.
Paediatrics & child health
Wong MP, Wadsworth L, Wu JK, Dix D
DOI: 10.1093/pch/13.6.507a
PubMed: 19436421
07/2008

Prevalence of post-thrombotic syndrome following asymptomatic thrombosis in survivors of acute lymphoblastic leukemia
Journal of Thrombosis and Haemostasis
S. KUHLE, M. SPAVOR, P. MASSICOTTE, J. HALTON, I. CHERRICK, D. DIX, D. MAHONEY, M. BAUMAN, S. DESAI, L. G. MITCHELL
DOI: 10.1111/j.1538-7836.2008.02901.x
04/2008

Screening for submicroscopic chromosomal rearrangements in Wilms tumor using whole-genome microarrays.
Cancer genetics and cytogenetics
Rassekh SR, Chan S, Harvard C, Dix D, Qiao Y, Rajcan-Separovic E
DOI: 10.1016/j.cancergencyto.2007.12.015
PubMed: 18406869
04/2008

Impact of Caring for a Child With Cancer on Parents’ Health-Related Quality of Life
Journal of Clinical Oncology
Anne F. Klassen, Robert Klaassen, David Dix, Sheila Pritchard, Rochelle Yanofsky, Maureen O'Donnell, Amie Scott, Lillian Sung
DOI: 10.1200/jco.2007.15.2835
2008

Retinal hemorrhages requiring vitrectomy in a patient with hemophagocytic lymphohistiocytosis
Pediatric Blood & Cancer
Gregory M.T. Guilcher, Jane A. Gardiner, Louis D. Wadsworth, David B. Dix
DOI: 10.1002/pbc.21542
2008

Multiple intracranial tumors in Philadelphia chromosome positive acute lymphoblastic leukemia: Successful treatment following aggressive supportive care, early cranial radiation, high dose chemotherapy and imatinib
Pediatric Blood & Cancer
Geoff D.E. Cuvelier, Aleksander M. Vitali, Jason C. Ford, David B. Dix
DOI: 10.1002/pbc.21562
2008

Identification of paediatric cancer patients with poor quality of life
British Journal of Cancer
L Sung, R J Klaassen, D Dix, S Pritchard, R Yanofsky, B Dzolganovski, R Almeida, A Klassen
DOI: 10.1038/sj.bjc.6604826
2008

Hearing loss at end of life in pediatric oncology
Pediatric Blood & Cancer
06/2007

Developing a literature base to understand the caregiving experience of parents of children with cancer: a systematic review of factors related to parental health and well-being
Supportive Care in Cancer
Anne Klassen, Parminder Raina, Samantha Reineking, David Dix, Sheila Pritchard, Maureen O’Donnell
DOI: 10.1007/s00520-007-0243-x
03/2007

Low Incidence of Ototoxicity With Continuous Infusion of Cisplatin in the Treatment of Pediatric Germ Cell Tumors
Journal of Pediatric Hematology/Oncology
Abha A Gupta, Michael Capra, Vicky Papaioannou, Gregg Hall, Ronnen Maze, David Dix, Sheila Weitzman
DOI: 10.1097/01.mph.0000199586.98926.8e
02/2006

Utility of anti-xa monitoring in children receiving enoxaparin for therapeutic anticoagulation.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
Leung M, Ho SH, Hamilton DP, Wu JK, Dix DB, Wadsworth LD, Ensom MH
DOI: 10.5863/1551-6776-10.1.43
PubMed: 23118625
01/2005

An Assessment of Published Pediatric Dosage Guidelines for EnoxaparinA Retrospective Review
Journal of Pediatric Hematology/Oncology
Sharon H Ho, John K Wu, Donald P Hamilton, David B Dix, Louis D Wadsworth
DOI: 10.1097/01.mph.0000139453.22338.d9
09/2004

Ewing sarcoma: Favourable results with combined modality therapy and conservative use of radiotherapy
Pediatric Blood & Cancer
George Zogopoulos, Lindsay Teskey, Lillian Sung, David Dix, Ronald Grant, Mark L. Greenberg, Sheila Weitzman
DOI: 10.1002/pbc.20037
07/2004

Natural history of arterial and venous thrombosis in children treated with low molecular weight heparin: a longitudinal study by ultrasound
Journal of Thrombosis and Haemostasis
S. Revel-Vilk and A. Sharathkumar and P. Massicotte and V. Marzinotto and A. Daneman and D. Dix and A. Chan
DOI: 10.1111/j.1538-7836.2004.00532.x
01/2004

Epstein-Barr virus-associated lymphoproliferative disorder in a child undergoing therapy for localized rhabdomyosarcoma
Medical and Pediatric Oncology
Lillian Sung, David Dix, Upton Allen, Sheila Weitzman, Ernest Cutz, David Malkin
DOI: 10.1002/(sici)1096-911x(200005)34:53.0.co;2-k
05/2000

The use of low molecular weight heparin in pediatric patients: A prospective cohort study
The Journal of Pediatrics
David Dix, Maureen Andrew, Velma Marzinotto, Karen Charpentier, Suzanne Bridge, Paul Monagle, Gabrielle deVeber, Michael Leaker, Anthony K.C. Chan, M.Patricia Massicotte
DOI: 10.1016/s0022-3476(00)90005-2
04/2000

#667 Determination of trough anti-factor Xa levels in pediatric patients on low molecular weight heparin (LMWH)
Journal of Pediatric Hematology/Oncology
D. Dix, K. Charpentier, C. Sparling, M. P. Massicotte
DOI: 10.1097/00043426-199807000-00104
07/1998

#668 Use of low molecular weight heparin (LMWH) for the management of venous thromboembolic disease (VTE) in children undergoing bone marrow transplant (BMT)
Journal of Pediatric Hematology/Oncology
D. Dix, V. Marzinotto, P. Monagle, M. Freedman, E. F. Saunders, J. Doyle, S. Calderwood, M. P. Massicotte
DOI: 10.1097/00043426-199807000-00105
07/1998

The Use of Low Molecular Weight Heparin in Pediatric Patients: Review of A Single Institution Experience • 761
Pediatric Research
D Dix, V Marzinotto, M Leaker, P Massicotte, S Bridges, M Andrew
DOI: 10.1203/00006450-199804001-00782
04/1998

Central venous catheter related thrombosis in children: Analysis of the Canadian Registry of Venous Thromboembolic Complications
The Journal of Pediatrics
M.Patricia Massicotte, David Dix, Paul Monagle, Margaret Adams, Maureen Andrew
DOI: 10.1016/s0022-3476(98)70149-0
1998

Pleural Relapse During Hematopoietic Remission in Childhood Acute Lymphoblastic Leukemia
Journal of Pediatric Hematology/Oncology
David B. Dix, Ronald A. Anderson, Deborah E. McFadden, Louis D. Wadsworth
DOI: 10.1097/00043426-199709000-00013
09/1997

Research

Steroid-induced osteoporosis in the pediatric population - Canadian incidence study (STOPP-CIS)
There is a growing list of pediatric osteoporotic conditions associated with chronic disease, and studies suggest that glucocorticoids play a pivotal role in the pathogenesis of osteoporosis secondary to childhood illness. Despite the disadvantages on skeletal metabolism, these drugs are uniformly a part of Canadian treatment protocols for children with leukaemia and nephritic syndrome. While a number of studies attest to the devastating effects of glucocorticoids on the bone health of children, there are few that document the natural history of skeletal morbidity in pediatric steroid-induced osteoporosis (SO).

Predicting risk of infection in Canadian children receiving chemotherapy for AML
Invasive infection is the primary cause of death for approximately 7-10% of children with acute myeloid leukemia (AML). There is great variability in the rate and outcome of infection, even among children receiving identical chemotherapy. Despite the importance of infection, infectious outcomes for children with AML have been poorly described and there is little ability to predict which child with AML will develop life-threatening invasive infection. This study may afford us the ability to predict those at highest risk, as any intervention targeted at decreasing infection will likely be associated with considerable toxicity, adverse outcomes or costs.

Langherans cell histiocytosis III
Langerhans cell histiocytosis (LCH) is a rare disease that is characterized by the accumulation and proliferation of abnormal bone marrow-derived Langerhans cells. These cells form infiltrates that may be found in various organs and to different extents. The course of disease is unpredictable, varying from spontaneous regression and resolution to rapid progression and death or repeated recurrence with the risk of permanent consequences. Multiple organ involvement, which is particularly frequent in young children under 2 years, carries the risk of a poor outcome. Current studies build on previous experience to further advance treatment regimens.