Overview

My research pertains to the development of clinical tools for clinicians and members of the public to obtain factual information about drug interactions between prescription medications and substances of abuse.

Note: Dr. Elbe only accepts research students from the UBC Faculty of Pharmaceutical Sciences (directed studies).

Publications

Celecoxib versus placebo as an adjunct to treatment-as-usual in children and youth with obsessive–compulsive disorder: protocol for a single-site randomised quadruple-blind phase II study
BMJ Open
Clara Westwell-Roper and John R Best and Dean Elbe and Megan MacFadden and Susan Baer and Lori Tucker and Antony Au and Zainab Naqqash and Boyee Lin and Cynthia Lu and S Evelyn Stewart
DOI: 10.1136/bmjopen-2021-054296
01/2022

Sleep as an outcome measure in ADHD randomized controlled trials: A scoping review
Sleep Medicine Reviews
McWilliams, S. and Zhou, T. and Stockler, S. and Elbe, D. and Ipsiroglu, O.S.
DOI: 10.1016/j.smrv.2022.101613
2022

Understanding patient characteristics and medication prescriptions in children with mental health and neurodevelopmental disorders referred to a sleep clinic—A quality improvement/quality assurance analysis
Frontiers in Psychiatry
Ipsiroglu, O.S. and Bhathella, J. and Boldut, R.P. and Elbe, D. and Hill, O. and Keys, E. and McWilliams, S. and Silvestri, R. and Wensley, D.F.
DOI: 10.3389/fpsyt.2022.878356
2022

Psychiatric Manifestations in Patients with Biopterin Defects
Neuropediatrics
Parfyonov, M. and Friedlander, R. and Banno, B. and Elbe, D. and Horvath, G.
DOI: 10.1055/s-0042-1742323
2022

Response to “Clomipramine in Combination with Fluvoxamine: A Potent Medication Combination for Severe or Refractory Pediatric OCD”
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Fung, R. and Elbe, D. and Evelyn Stewart, S.
2021

Retrospective Review of Fluvoxamine-Clomipramine Combination Therapy in Obsessive-Compulsive Disorder in Children and Adolescents
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Fung, R. and Elbe, D. and Stewart, S.E.
2021

Recommended academic reading
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D.
2021

Retrospective review of clozapine use in children and adolescents
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Komaryk, A. and Elbe, D. and Burgess, L.
2021

Management of Acute Agitation and Aggression in Children and Adolescents with Pro Re Nata Oral Immediate Release Antipsychotics in the Pediatric Emergency Department.
Journal of child and adolescent psychopharmacology
Yip L and Aeng E and Elbe D
DOI: 10.1089/cap.2019.0171
PubMed: 33035069
10/2020

Psychopharmacology Challenge.
Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent
Elbe D
PubMed: 32774402
08/2020

Switching from Clonidine Immediate-Release to Guanfacine Extended-Release.
Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent
Elbe D
PubMed: 32405313
05/2020

Psychopharmacology challenge
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D.
2020

Switching from clonidine immediate-release to guanfacine extended-release
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D.
2020

Lifesaving Electroconvulsive Therapy for a Child With Autism Spectrum Disorder, Severe Self-Injurious Behavior, and Neuroleptic Malignant Syndrome.
The journal of ECT
González-Romero MF and Avina-Galindo AM and Elbe D and Friedlander R and Vila-Rodriguez F
DOI: 10.1097/yct.0000000000000598
PubMed: 31022044
04/2019

Formal Psychiatry Resident Rotations with a Clinical Pharmacy Specialist: Preliminary Experience at BC Children's Hospital.
Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent
Elbe D and Chapman A
PubMed: 31001346
03/2019

Formal psychiatry resident rotations with a clinical pharmacy specialist: Preliminary experience at BC children’s hospital
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D. and Chapman, A.
2019

Lifesaving Electroconvulsive Therapy for a Child with Autism Spectrum Disorder, Severe Self-Injurious Behavior, and Neuroleptic Malignant Syndrome
Journal of ECT
González-Romero, M.F. and Avina-Galindo, A.M. and Elbe, D. and Friedlander, R. and Vila-Rodriguez, F.
DOI: 10.1097/YCT.0000000000000598
2019

Clinical Handbook of Psychotropic Drugs for Children and Adolescents
DOI: 10.1027/00550-000
2018

Stimulant ‘rapid metabolizers’: wrong label, real phenomena
ADHD Attention Deficit and Hyperactivity Disorders
Weiss, M.D. and Surman, C.B.H. and Elbe, D.
DOI: 10.1007/s12402-017-0242-9
2018

Clinical Handbook of Psychotropic Drugs
DOI: 10.1027/00496-000
2017

Manic Reaction in a Child Induced by Guanfacine-Extended Release.
Elbe D and Perel-Panar C and Wicholas L
DOI: 10.1089/cap.2016.0050
PubMed: 27228067
08/2016

Update on the Use of SSRIs and SNRIs with Children and Adolescents in Clinical Practice.
Jane Garland E and Kutcher S and Virani A and Elbe D
PubMed: 27047551
2016

Therapeutic drug levels of second generation antipsychotics in youth: a systematic review.
Whitney Z and Boyda HN and Procyshyn RM and Elbe D and Black T and Eslami A and Barr AM
DOI: 10.1089/cap.2014.0044
PubMed: 25803501
04/2015

Do We Know If They Work and If They Are Safe
The Science and Ethics of Antipsychotic Use in Children
Dean Elbe and Edel Mc Glanaghy and Tim F. Oberlander
DOI: 10.1016/b978-0-12-800016-8.00003-9
2015

Pathways to Overmedication and Polypharmacy: Case Examples from Adolescents with Fetal Alcohol Spectrum Disorders
The Science and Ethics of Antipsychotic Use in Children
Ipsiroglu, O. and Berger, M. and Lin, T. and Elbe, D. and Stockler, S. and Carleton, B.
DOI: 10.1016/B978-0-12-800016-8.00006-4
2015

Do We Know If They Work and If They Are Safe: Second-Generation Antipsychotics for Treatment of Autism Spectrum Disorders and Disruptive Behavior Disorders in Children and Adolescents
The Science and Ethics of Antipsychotic Use in Children
Elbe, D. and Mc Glanaghy, E. and Oberlander, T.F.
DOI: 10.1016/B978-0-12-800016-8.00003-9
2015

Update on the use of SSRIS and SNRIS with children and adolescents in clinical practice
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Garland, E.J. and Kutcher, S. and Virani, A. and Elbe, D.
2015

Pathways to Overmedication and Polypharmacy
The Science and Ethics of Antipsychotic Use in Children
DOI: 10.1016/b978-0-12-800016-8.00006-4
2015

Managing ADHD and disruptive behaviour disorders with combination psychostimulant and antipsychotic treatment.
Elbe D and Barr AM and Honer WG and Procyshyn RM
DOI: 10.1503/jpn.130288
PubMed: 24758945
05/2014

Lack of detectable serum levels following topical fluoxetine administration in a child.
Elbe D and Wicholas L
DOI: 10.1089/cap.2013.0078
PubMed: 24679176
03/2014

Focus on Guanfacine Extended-release: A Review of its Use in Child and Adolescent Psychiatry.
Elbe D and Reddy D
PubMed: 24516477
02/2014

Prevalence and patterns of antipsychotic use in youth at the time of admission and discharge from an inpatient psychiatric facility.
Procyshyn RM and Su J and Elbe D and Liu AY and Panenka WJ and Davidson J and Honer WG and Barr AM
DOI: 10.1097/jcp.0b013e3182a607dd
PubMed: 24346744
02/2014

Clinical Handbook of Psychotropic Drugs for Children and Adolescents
DOI: 10.1027/00456-000
2014

Prevalence and patterns of antipsychotic use in youth at the time of admission and discharge from an inpatient psychiatric facility
Journal of Clinical Psychopharmacology
Procyshyn, R.M. and Su, J. and Elbe, D. and Liu, A.Y. and Panenka, W.J. and Davidson, J. and Honer, W.G. and Barr, A.M.
DOI: 10.1097/JCP.0b013e3182a607dd
2014

Focus on guanfacine extended-release: A review of its use in child and adolescent psychiatry
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D. and Reddy, D.
2014

A retrospective study of antipsychotic drug switching in a pediatric population.
Linton D and Procyshyn RM and Elbe D and Lee LH and Barr AM
DOI: 10.1186/1471-244x-13-248
PubMed: 24103197
2013

A retrospective study of antipsychotic drug switching in a pediatric population
BMC Psychiatry
Linton, D. and Procyshyn, R.M. and Elbe, D. and Lee, L.H.N. and Barr, A.M.
DOI: 10.1186/1471-244X-13-248
2013

Using Technology to Support Clinical Pharmacy Practice
UBC Pharmaceutical Sciences Student Journal
2013

Review: evidence on the comparative effectiveness and adverse effects of antipsychotics in young people is limited.
Reebye PN and Elbe D
DOI: 10.1136/ebmental-2012-100713
PubMed: 22730477
08/2012

Drug use evaluation of moxifloxacin (avelox) using a hand-held electronic device at a canadian teaching hospital.
Samilski JA and Lau TT and Elbe DH and Aulakh AK and Lun EM
PubMed: 22876087
05/2012

Review of the pharmacotherapy of irritability of autism.
Elbe D and Lalani Z
PubMed: 22548111
05/2012

Drug use evaluation of moxifloxacin (Avelox) using a hand-held electronic device at a canadian teaching hospital
P and T
Samilski, J.A.E. and Lau, T.T.Y. and Elbe, D.H.T. and Aulakh, A.K. and Lun, E.M.C.
2012

Review of the pharmacotherapy of irritability of autism
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D. and Lalani, Z.
2012

A review of escitalopram and citalopram in child and adolescent depression.
Carandang C and Jabbal R and Macbride A and Elbe D
PubMed: 22114615
11/2011

A Review of Escitalopram and Citalopram in Child and Adolescent Depression
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Carandang, C. and Jabbal, R. and MacBride, A. and Elbe, D.
2011

Focus on Lisdexamfetamine: A Review of its use in Child and Adolescent Psychiatry.
Elbe D and Macbride A and Reddy D
PubMed: 21037922
11/2010

Stahl?s Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, Third Edition.
Elbe D
08/2010

Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, Third Edition.
08/2010

Do Hospital and Community SSRI Usage Patterns in Children and Adolescents Match the Evidence?
Ronsley R and Elbe D and Smith DH and Garland EJ
PubMed: 20842278
08/2010

First do no harm: promoting an evidence-based approach to atypical antipsychotic use in children and adolescents.
Panagiotopoulos C and Ronsley R and Elbe D and Davidson J and Smith DH
PubMed: 20467549
05/2010

How does this happen? Part I: mechanisms of adverse drug reactions associated with psychotropic medications.
Elbe D and Savage R
PubMed: 20119566
02/2010

Focus on lisdexamfetamine: A review of its use in child and adolescent psychiatry
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D. and MacBride, A. and Reddy, D.
2010

Do hospital and community ssri usage patterns in children and adolescents match the evidence?
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Ronsley, R. and Elbe, D. and Smith, D.H. and Garland, E.J.
PubMed: 20842278
2010

How does this happen? Part I: Mechanisms of adverse drug reactions associated with psychotropic medications
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D. and Savage, R.
2010

First do no harm: Promoting an evidence-based approach to atypical antipsychotic use in children and adolescents
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Panagiotopoulos, C. and Ronsley, R. and Elbe, D. and Davidson, J. and Smith, D.H.
2010

Do hospital and community ssri usage patterns in children and adolescents match the evidence?
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Ronsley, R. and Elbe, D. and Smith, D.H. and Garland, E.J.
2010

Focus on aripiprazole: a review of its use in child and adolescent psychiatry.
Greenaway M and Elbe D
PubMed: 19718428
08/2009

The role of pharmacotherapy in the management of self-regulation difficulties in young children.
Reebye PN and Elbe D
PubMed: 19495438
05/2009

Commentary to QTc prolongation associated with atypical antipsychotic use in the treatment of adolescent-onset anorexia nervosa.
Elbe D
PubMed: 19270853
02/2009

The role of pharmacotherapy in the management of self-regulation difficulties in young children
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Reebye, P.N. and Elbe, D.
2009

Commentary to: QTc prolongation associated with atypical antipsychotic use in the treatment of adolescent-onset anorexia nervosa
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D.
2009

Focus on aripiprazole: A review of its use in child and adolescent psychiatry
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Greenaway, M. and Elbe, D.
2009

Focus on ziprasidone: a review of its use in child and adolescent psychiatry.
Elbe D and Carandang CG
PubMed: 19018327
11/2008

Focus on ziprasidone: A review of its use in child and adolescent psychiatry
Journal of the Canadian Academy of Child and Adolescent Psychiatry
Elbe, D. and Carandang, C.G.
2008

Moxifloxacin-warfarin interaction: a series of five case reports.
Elbe DH and Chang SW
DOI: 10.1345/aph.1e179
PubMed: 15632222
02/2005

Moxifloxacin-Warfarin interaction: A series of five case reports
Annals of Pharmacotherapy
Elbe, D.H.T. and Chang, S.W.
DOI: 10.1345/aph.1E179
2005

Visual compatibility of various injectable neuroleptic agents with benztropine and lorazepam in polypropylene syringes
Canadian Journal of Hospital Pharmacy
Elbe, D. and Condé, C.
2001

Bupropion-induced serum sickness-like reaction.
McCollom RA and Elbe DH and Ritchie AH
DOI: 10.1345/aph.19297
PubMed: 10772432
04/2000

Bupropion-Induced Serum Sickness–Like Reaction
The Annals of Pharmacotherapy
Robert A McCollom and Dean HT Elbe and Alec H Ritchie
DOI: 10.1345/1542-6270(2000)0342.3.co;2
04/2000

Use of cefixime in an IV to oral stepdown program to reduce antimicrobial costs
Formulary
Elbe, D. and Frighetto, L. and Nickoloff, D. and Jewesson, P.
1998

A survey of prescriber perceptions and practice of IV-PO stepdown anti-infective therapy
Canadian Journal of Hospital Pharmacy
Elbe, D. and Frighetto, L. and Nickoloff, D. and Jewesson, P.
1996