Biostatistics & Psychometrics Core

The Biostatistics & Psychometrics Core is a dynamic area that integrates methodologies and measurement tools to evaluate the efficacy and effectiveness of health care issues and interventions. The interdisciplinary unit has expertise in many areas including: statistical modeling and analyses; development of quantitative health research methods; and construction of reliable and valid health measurement scales, sensitive to the values and subjective experience of individual patients.

Research projects and interests include:

  • Development of quantitative health research methods
  • Development of questionnaires for health research

More details below.

Development of quantitative health research methods

Dr. Rollin Brant

  • The use of biostatistics in linear and non-linear mixed effects modeling and model criticism diagnostics as applied to child and maternal health research
  • The development of valid and reliable health measurement models in areas of pediatric emergency medicine, outcomes of prematurity, determinants of speech and cognitive development, and maternal health

Development of questionnaires for health research

Dr. Louise Mâsse

  • Psychometric evaluations including the development of questionnaires and reliability and validity assessment
  • Application of biostatistical analyses including classical test theory, item response theory, generalizability theory, structural equation modeling, among others


About Developmental Neurosciences & Child Health

Our investigators have research interests on topics that range from “neurons to neighbourhoods,” including behaviour and cognition, basic and clinical child neurosciences, child development, neuroimaging and neurophysiology, injury and environmental health, developmental disabilities and rehabilitation, mental health and addictions, biostatistics and neuroinformatics, vulnerable populations and population health, normal maternal-newborn care, palliative care, health policy, and other areas.


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Developmental Neurosciences & Child Health brings together a diverse group of researchers who make discoveries that enable innovative interventions to improve the well-being of children, youth and families.

Our diversity promotes synergy among developmental, neurobiological, behavioural, pharmacological, psychosocial and environmental sciences: in short, from neurons to neighbourhoods. Our focus is improved medical and surgical treatments, rehabilitation, prevention and health promotion.

Key Areas of Activity

The Developmental Neurosciences & Child Health research cluster promotes a collaborative, dynamic and interdisciplinary approach to research by interacting with others at the BC Children's Hospital Research Institute, at the University of British Columbia (UBC), in the external community, and internationally.

Our research involves scholars and scientists whose diverse interests include developmental pediatrics, pediatric neurology, neurosurgery and neuroimaging, child psychiatry, psychology, nursing sciences, developmental neurobiology, pharmacogenomics, statistics, epidemiology and health care policy.

Research Areas