Publications

Re-Irradiation in patients with Diffuse Intrinsic Pontine Gliomas: The Canadian Experience
Pediatric Blood & Cancer
Lassaletta, Alvaro and Strother, Douglas and Laperriere, Normand and Hukin, Juliette and Vanan, Magimairajan Issai and Goddard, Karen and Lafay-Cousin, Lucie and Johnston, Donna L. and Zelcer, Shayna and Zapotocky, Michal and Rajagopal, Revathi and Ramaswamy, Vijay and Hawkins, Cynthia and Tabori, Uri and Huang, Annie and Bartels, Ute and Bouffet, Eric
DOI: 10.1002/pbc.26988
01/2018

Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome.
Acta neuropathologica
Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C, Yip S, Hukin J, Sun Y, Schipper MJ, Chavez L, Margol A, Pekmezci M, Chung C, Banda A, Venneti S
DOI: 10.1007/s00401-017-1752-4
PubMed: 28733933
11/2017

Opsoclonus-Myoclonus Syndrome: A New Era of Improved Prognosis?
Pediatric Neurology
Armine Galstyan, Colin Wilbur, Kathryn Selby, Juliette Hukin
DOI: 10.1016/j.pediatrneurol.2017.03.011
07/2017

Determinants of social competence in pediatric brain tumor survivors who participated in an intervention study
Supportive Care in Cancer
Maru Barrera, Eshetu G. Atenafu, Fiona Schulte, Ute Bartels, Lillian Sung, Laura Janzen, Joanna Chung, Danielle Cataudella, Kelly Hancock, Amani Saleh, Douglas Strother, Dina McConnell, Andrea Downie, Juliette Hukin, Shayna Zelcer
DOI: 10.1007/s00520-017-3708-6
04/2017

Determinants of quality of life outcomes for survivors of pediatric brain tumorsBarrera et al.
Pediatric Blood & Cancer
Maru Barrera, Eshetu G. Atenafu, Fiona Schulte, Ute Bartels, Lillian Sung, Laura Janzen, Joanna Chung, Danielle Cataudella, Kelly Hancock, Amani Saleh, Douglas Strother, Dina McConnell, Andrea Downie, Juliette Hukin, Shayna Zelcer
DOI: 10.1002/pbc.26481
03/2017

Atypical teratoid rhabdoid tumor in the first year of life: the Canadian ATRT registry experience and review of the literature.
Journal of neuro-oncology
Fossey M, Li H, Afzal S, Carret AS, Eisenstat DD, Fleming A, Hukin J, Hawkins C, Jabado N, Johnston D, Brown T, Larouche V, Scheinemann K, Lafay-Cousin L
DOI: 10.1007/s11060-016-2353-0
PubMed: 28102486
03/2017

A randomized control intervention trial to improve social skills and quality of life in pediatric brain tumor survivors
Psycho-Oncology
Maru Barrera, Eshetu G. Atenafu, Lillian Sung, Ute Bartels, Fiona Schulte, Joanna Chung, Danielle Cataudella, Kelly Hancock, Laura Janzen, Amani Saleh, Douglas Strother, Andrea Downie, Shayna Zelcer, Juliette Hukin, Dina McConnell
DOI: 10.1002/pon.4385
2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.
Cancer cell
Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, Huang A
DOI: 10.1016/j.ccell.2016.11.003
PubMed: 27960086
12/2016

Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study
Journal of Clinical Oncology
Alvaro Lassaletta, Katrin Scheinemann, Shayna M. Zelcer, Juliette Hukin, Beverley A. Wilson, Nada Jabado, Anne Sophie Carret, Lucie Lafay-Cousin, Valerie Larouche, Cynthia E. Hawkins, Gregory Russell Pond, Ken Poskitt, Daniel Keene, Donna L. Johnston, David D. Eisenstat, Rahul Krishnatry, Matthew Mistry, Anthony Arnoldo, Vijay Ramaswamy, Annie Huang, Ute Bartels, Uri Tabori, Eric Bouffet
DOI: 10.1200/jco.2016.68.1585
10/2016

Episodic ataxia associated with a de novo SCN2A mutation
European Journal of Paediatric Neurology
Emma L. Leach, Clara D.M. van Karnebeek, Katelin N. Townsend, Maja Tarailo-Graovac, Juliette Hukin, William T. Gibson
DOI: 10.1016/j.ejpn.2016.05.020
09/2016

Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma
Acta Neuropathologica Communications
Scott Ryall, Rahul Krishnatry, Anthony Arnoldo, Pawel Buczkowicz, Matthew Mistry, Robert Siddaway, Cino Ling, Sanja Pajovic, Man Yu, Joshua B. Rubin, Juliette Hukin, Paul Steinbok, Ute Bartels, Eric Bouffet, Uri Tabori, Cynthia Hawkins
DOI: 10.1186/s40478-016-0353-0
08/2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Ramaswamy V, Hielscher T, Mack SC, Lassaletta A, Lin T, Pajtler KW, Jones DT, Luu B, Cavalli FM, Aldape K, Remke M, Mynarek M, Rutkowski S, Taylor MD
DOI: 10.1200/jco.2015.65.7825
PubMed: 27269943
07/2016

Ophthalmological outcomes of patients treated for pineal region tumors
Journal of Neurosurgery: Pediatrics
Elizabeth V. Hankinson, Christopher J. Lyons, Juliette Hukin, David D. Cochrane
DOI: 10.3171/2015.10.peds15415
05/2016

Eye Findings on Vigabatrin and Taurine Treatment in Two Patients with Succinic Semialdehyde Dehydrogenase Deficiency
Neuropediatrics
Juliette Hukin, Sylvia Stockler-Ipsiroglu, Maryam Aroichane, Gabriella-Ana Horvath
DOI: 10.1055/s-0036-1583183
04/2016

White matter and information processing speed following treatment with cranial-spinal radiation for pediatric brain tumor.
Neuropsychology
Nadia Scantlebury, Eric Bouffet, Suzanne Laughlin, Douglas Strother, Dina McConnell, Juliette Hukin, Christopher Fryer, Normand Laperriere, Isabelle Montour-Proulx, Daniel Keene, Adam Fleming, Nada Jabado, Fang Liu, Lily Riggs, Nicole Law, Donald J. Mabbott
DOI: 10.1037/neu0000258
2016

Longitudinal Outcomes in the 2014 Acute Flaccid Paralysis Cluster in CanadaA Nationwide Study
Journal of Child Neurology
Carmen Yea, Ari Bitnun, Joan Robinson, Aleksandra Mineyko, Michelle Barton, Jean K. Mah, Jiri Vajsar, Susan Richardson, Christoph Licht, Jason Brophy, Megan Crone, Shalini Desai, Juliette Hukin, Kevin Jones, Katherine Muir, Jeffrey M. Pernica, Robert Pless, Daniela Pohl, Mubeen F. Rafay, Kathryn Selby, Sunita Venkateswaran, Geneviève Bernard, E. Ann Yeh
DOI: 10.1177/0883073816680770
2016

Pediatric thalamic tumors in the MRI era: a Canadian perspective
Child's Nervous System
Paul Steinbok, Chittur Viswanathan Gopalakrishnan, Alexander R. Hengel, Aleksander M. Vitali, Ken Poskitt, Cynthia Hawkins, James Drake, Maria Lamberti-Pasculli, Olufemi Ajani, Walter Hader, Vivek Mehta, P. Daniel McNeely, Patrick J. McDonald, Adrianna Ranger, Michael Vassilyadi, Jeff Atkinson, Scott Ryall, David D. Eisenstat, Juliette Hukin
DOI: 10.1007/s00381-015-2968-z
11/2015

Assessing the accuracy of death records and pre-mortem clinical diagnoses in children diagnosed with brain tumors: A retrospective chart review of children in British Columbia, Canada
Pathology - Research and Practice
Haroon Hasan, Glenda Hendson, A. Fuchsia Howard, Juliette Hukin, Christopher Dunham, Tareq Ahmed, Andrea C. Lo, Karen Goddard
DOI: 10.1016/j.prp.2015.06.008
10/2015

Intracystic interferon-a treatment leads to neurotoxicity in craniopharyngioma: case report
Journal of Neurosurgery: Pediatrics
Julia Sharma, Christopher M. Bonfield, Ash Singhal, Juliette Hukin, Paul Steinbok
DOI: 10.3171/2015.2.peds14656
09/2015

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.
The Lancet. Oncology
Torchia J, Picard D, Lafay-Cousin L, Hawkins CE, Kim SK, Letourneau L, Ra YS, Ho KC, Chan TS, Sin-Chan P, Dunham CP, Yip S, Ng HK, Lu JQ, Albrecht S, Huang A
DOI: 10.1016/s1470-2045(15)70114-2
PubMed: 25882982
05/2015

AT-07 * SUCCESSFUL TREATMENT OF ATRT PATIENTS WITHOUT ADJUVANT RADIATION: A MULTI INSTITUTIONAL CANADIAN EXPERIENCE
Neuro-Oncology
D. Ku, L. Lafay-Cousin, C. Fryer, J. Hukin, D. Strother, A. Huang, E. Bouffet
DOI: 10.1093/neuonc/nov061.6
04/2015

Neurocognitive evaluation of long term survivors of atypical teratoid rhabdoid tumors (ATRT): The Canadian registry experienceNeurocognitive Outcome of ATRT Survivors
Pediatric Blood & Cancer
Lucie Lafay-Cousin, Taryn Fay-McClymont, Donna Johnston, Chris Fryer, Katrin Scheinemann, Adam Fleming, Juliette Hukin, Laura Janzen, Sharon Guger, Douglas Strother, Donald Mabbott, Annie Huang, Eric Bouffet
DOI: 10.1002/pbc.25441
03/2015

EZH2 expression is a prognostic factor in childhood intracranial ependymoma: A Canadian Pediatric Brain Tumor Consortium studyEZH2 and Poor Prognosis in Ependymoma
Cancer
Amanda M. Li, Christopher Dunham, Uri Tabori, Anne-Sophie Carret, P. Daniel McNeely, Donna Johnston, Lucie Lafay-Cousin, Beverly Wilson, David D. Eisenstat, Nada Jabado, Shayna Zelcer, Mariana Silva, Katrin Scheinemann, Christopher Fryer, Glenda Hendson, Abbas Fotovati, Cynthia Hawkins, Stephen Yip, Sandra E. Dunn, Juliette Hukin
DOI: 10.1002/cncr.29198
01/2015

Low Grade Glioma
Pediatric Neuro-oncology
Katrin Scheinemann, Juliette Hukin
DOI: 10.1007/978-1-4939-1541-5_9
2015

Ependymoma
Pediatric Neuro-oncology
Juliette Hukin, John-Paul Kilday, Uri Tabori
DOI: 10.1007/978-1-4939-1541-5_13
2015

The role of resection alone in select children with intracranial ependymoma: the Canadian Pediatric Brain Tumour Consortium experience
Child's Nervous System
Tamir Ailon, Christopher Dunham, Anne-Sophie Carret, Uri Tabori, P. Daniel Mcneely, Shayna Zelcer, Beverley Wilson, Lucie Lafay-Cousin, Donna Johnston, David D. Eisenstat, Marianna Silva, Nada Jabado, Karen Jane Goddard, Chris Fryer, Glenda Hendson, Cynthia Hawkins, Sandra Dunn, Stephen Yip, Ashutosh Singhal, Juliette Hukin
DOI: 10.1007/s00381-014-2575-4
11/2014

White matter compromise predicts poor intellectual outcome in survivors of pediatric low-grade glioma
Neuro-Oncology
F. Liu, N. Scantlebury, U. Tabori, E. Bouffet, S. Laughlin, D. Strother, D. McConnell, J. Hukin, C. Fryer, M.-E. Briere, I. Montour-Proulx, D. Keene, F. Wang, D. J. Mabbott
DOI: 10.1093/neuonc/nou306
11/2014

Epidemiology of malignant pontine gliomas (MPG) in the paediatric population in Canada: A study of the Canadian paediatric brain tumour consortium (CPBTC)
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Samina Afzal, Anne-Sophie Carret, Adam Fleming, Valerie Larouche, Shayna Zelcer, Donna L. Johnston, Maria Kostova, Chris Mpofu, Douglas Strother, Lucie Lafay-Cousin, David Eisenstat, Chris Fryer, Juliette Hukin, Ute Bartels, Eric Bouffet
DOI: 10.1017/cjn.2014.86
10/2014

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations.
Nature genetics
Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Hawkins C
DOI: 10.1038/ng.2936
PubMed: 24705254
05/2014

Pleomorphic xanthoastrocytoma of the spinal cord: case report and literature review
Clinical Neuropathology
Sumit Das, Stephen Yip, Juliette Hukin, Douglas Cochrane, Christopher Dunham
DOI: 10.5414/np300689
05/2014

Late effects in survivors of childhood CNS tumors treated on Head Start I and II protocolsLate Effects in Head Start I and II Survivors
Pediatric Blood & Cancer
Aniket Saha, Christina G. Salley, Preeti Saigal, Linda Rolnitzky, Judith Goldberg, Suzanne Scott, Randal Olshefski, Juliette Hukin, Stephen A. Sands, Jonathan Finlay, Sharon L. Gardner
DOI: 10.1002/pbc.25064
05/2014

Multimodality therapy for CNS mixed malignant germ cell tumors (MMGCT): results of a phase II multi-institutional study
Journal of Neuro-Oncology
Patricia L. Robertson, Regina Jakacki, Juliette Hukin, Joao Siffert, Jeffrey C. Allen
DOI: 10.1007/s11060-013-1306-0
04/2014

De-escalation of therapy for pediatric medulloblastoma: Trade-offs between quality of life and survivalTreatment Preferences for Medulloblastoma
Pediatric Blood & Cancer
Natalie Henrich, Carlo A. Marra, Louise Gastonguay, Donald Mabbott, David Malkin, Chris Fryer, Eric Bouffet, Michael D. Taylor, Juliette Hukin, Nadia Scantlebury, Larry Lynd
DOI: 10.1002/pbc.24990
02/2014

Changes to Memory Structures in Children Treated for Posterior Fossa Tumors
Journal of the International Neuropsychological Society
Lily Riggs, Eric Bouffet, Suzanne Laughlin, Normand Laperriere, Fang Liu, Jovanka Skocic, Nadia Scantlebury, Frank Wang, Nicholas J. Schoenhoff, Douglas Strother, Juliette Hukin, Christopher Fryer, Dina McConnell, Donald J. Mabbott
DOI: 10.1017/s135561771300129x
01/2014

Chemotherapy for Tumors
Nervous System of Children
2014

Growing teratoma syndrome in intracranial non-germinomatous germ cell tumors (iNGGCTs): a risk for secondary malignant transformation—a report of two cases
Child's Nervous System
Torin Glass, D. Douglas Cochrane, Shahrad Rod Rassekh, Karen Goddard, Juliette Hukin
DOI: 10.1007/s00381-013-2295-1
10/2013

Optic pathway gliomas in adolescence--time to challenge treatment choices?
Neuro-Oncology
A. Lee Chong, J. D. Pole, K. Scheinemann, J. Hukin, U. Tabori, A. Huang, E. Bouffet, U. Bartels
DOI: 10.1093/neuonc/nos312
01/2013

Novel Mutations in FA2H-Associated NeurodegenerationAn Underrecognized Condition?
Journal of Child Neurology
Rosemarie Rupps, Juliette Hukin, Martha Balicki, Saadet Mercimek-Mahmutoglu, Arndt Rolfs, Cristina Dias
DOI: 10.1177/0883073812458538
09/2012

Clinical and neuroanatomical predictors of cerebellar mutism syndrome
Neuro-Oncology
N. Law, M. Greenberg, E. Bouffet, M. D. Taylor, S. Laughlin, D. Strother, C. Fryer, D. McConnell, J. Hukin, C. Kaise, F. Wang, D. J. Mabbott
DOI: 10.1093/neuonc/nos160
09/2012

Phase II Study of Weekly Vinblastine in Recurrent or Refractory Pediatric Low-Grade Glioma
Journal of Clinical Oncology
Eric Bouffet, Regina Jakacki, Stewart Goldman, Darren Hargrave, Cynthia Hawkins, Manohar Shroff, Juliette Hukin, Ute Bartels, Nicholas Foreman, Stewart Kellie, Joanne Hilden, Michael Etzl, Beverly Wilson, Derek Stephens, Uri Tabori, Sylvain Baruchel
DOI: 10.1200/jco.2011.34.5843
04/2012

Intracranial tumors in infants: long-term functional outcome, survival, and its predictors
Child's Nervous System
Shibu Pillai, Mary Metrie, Christopher Dunham, Michael Sargent, Juliette Hukin, Paul Steinbok
DOI: 10.1007/s00381-012-1707-y
02/2012

Atypical Teratoid Rhabdoid Tumors (ATRTs): The British Columbia's Children's Hospital's Experience, 1986-2006BCCH ATRTs, 1986-2006
Brain Pathology
Adam J. Fleming, Juliette Hukin, Rod Rassekh, Christopher Fryer, James Kim, Anat Stemmer-Rachamimov, Diane K. Birks, Annie Huang, Stephen Yip, Christopher Dunham
DOI: 10.1111/j.1750-3639.2011.00561.x
02/2012

Cystic Craniopharyngiomas: Intratumoral Bleomycin Therapy
Tumors of the Central Nervous System, Volume 8
Paul Steinbok, Juliette Hukin
DOI: 10.1007/978-94-007-4213-0_23
2012

Supratentorial Primitive Neuroectodermal Tumors
Tumors of the Central Nervous System, Volume 4
Mohit Singh, Juliette Hukin
DOI: 10.1007/978-94-007-1706-0_2
08/2011

Cerebello–thalamo–cerebral connections in pediatric brain tumor patients: Impact on working memory
NeuroImage
Nicole Law, Eric Bouffet, Suzanne Laughlin, Normand Laperriere, Marie-Eve Brière, Douglas Strother, Dina McConnell, Juliette Hukin, Christopher Fryer, Conrad Rockel, Jolynn Dickson, Donald Mabbott
DOI: 10.1016/j.neuroimage.2011.03.065
06/2011

The use and effectiveness of temozolomide in children with central nervous system tumours: a survey from the Canadian Paediatric Brain Tumour Consortium
Current Oncology
U. Bartels, S. Baruchel, A.S. Carret, B. Crooks, J. Hukin, D. Johnston, M. Silva, D. Strother, B. Wilson, S. Zelcer, D. Eisenstat, L. Sung, E. Bouffet
DOI: 10.3747/co.v18i1.675
02/2011

Childhood CNS Pediatric Primitive Neuroectodermal Tumors
Tumors of the Central Nervous System
11/2010

Intracystic treatments for craniopharyngioma
Neurosurgical Focus
Paul Steinbok, Juliette Hukin
DOI: 10.3171/2010.1.focus09315
04/2010

Late mortality in pediatric patients with craniopharyngioma
Journal of Neuro-Oncology
Johannes Visser, Juliette Hukin, Michael Sargent, Paul Steinbok, Karen Goddard, Chris Fryer
DOI: 10.1007/s11060-010-0145-5
03/2010

A multi-centre Canadian pilot study of metronomic temozolomide combined with radiotherapy for newly diagnosed paediatric brainstem glioma
European Journal of Cancer
Julia R. Sharp, Eric Bouffet, Diana Stempak, Janet Gammon, Derek Stephens, Donna L. Johnston, David Eisenstat, Juliette Hukin, Yvan Samson, Ute Bartels, Uri Tabori, Annie Huang, Sylvain Baruchel
DOI: 10.1016/j.ejca.2010.06.115
2010

A Canadian paediatric brain tumour consortium (CPBTC) phase II molecularly targeted study of imatinib in recurrent and refractory paediatric central nervous system tumours
European Journal of Cancer
Sylvain Baruchel, Julia R. Sharp, Ute Bartels, Juliette Hukin, Isaac Odame, Carol Portwine, Doug Strother, Chris Fryer, Jackie Halton, Merrill J. Egorin, Rui Manuel Reis, Olga Martinho, Diana Stempak, Cynthia Hawkins, Janet Gammon, Eric Bouffet
DOI: 10.1016/j.ejca.2009.05.008
09/2009

Occurrence of Basal Ganglia Germ Cell Tumors Without a Mass
Archives of Neurology
Salah Almubarak, Yee-Chiung Gan, Paul Steinbok, Glenda Hendson, Ken Poskitt, Helen Nadel, Karen Goddard, Juliette Hukin
DOI: 10.1001/archneurol.2009.74
06/2009

Atypical Presentation of Basal Ganglia Germ Cell Tumors in Children
Journal of Neurosurgery: Pediatrics
Paul Steinbok, Salah Almubarak, Peter Gan, Glenda Hendson, Kenneth Poskitt, Helen Nadel, Karen Goddard, Juliette Hukin
DOI: 10.3171/ped/2008/1/4/paper11
04/2008

Intensive chemotherapy followed by consolidative myeloablative chemotherapy with autologous hematopoietic cell rescue (AuHCR) in young children with newly diagnosed supratentorial primitive neuroectodermal tumors (sPNETs): Report of the Head Start I and II experience
Pediatric Blood & Cancer
Jason Fangusaro, Jonathan Finlay, Richard Sposto, Lingyun Ji, Monirath Saly, Stergios Zacharoulis, Shahab Asgharzadeh, Minnie Abromowitch, Randal Olshefski, Steven Halpern, Ronald Dubowy, Melanie Comito, Blanca Diez, Stewart Kellie, Juliette Hukin, Marc Rosenblum, Ira Dunkel, Douglas C. Miller, Jeffrey Allen, Sharon Gardner
DOI: 10.1002/pbc.21307
02/2008

Carboplatin hypersensitivity reaction in pediatric patients with low-grade gliomaA Canadian Pediatric Brain Tumor Consortium experience
Cancer
Lucie Lafay-Cousin, Lillian Sung, Anne-Sophie Carret, Juliette Hukin, Beverly Wilson, Donna L. Johnston, Shayna Zelcer, Mariana Silva, Isaac Odame, Chris Mpofu, Douglas Strother, Eric Bouffet
DOI: 10.1002/cncr.23249
2008

Isolated sulfite oxidase deficiency in the newborn: lactic acidaemia and leukoencephalopathy.
Neuropediatrics
Basheer SN, Waters PJ, Lam CW, Acquaviva-Bourdain C, Hendson G, Poskitt K, Hukin J
DOI: 10.1055/s-2007-981484
PubMed: 17607604
02/2007

Intracystic bleomycin therapy for craniopharyngioma in childrenThe Canadian experience
Cancer
Juliette Hukin, Paul Steinbok, Lucie Lafay-Cousin, Glenda Hendson, Douglas Strother, Claude Mercier, Yvan Samson, William Howes, Eric Bouffet
DOI: 10.1002/cncr.22633
2007

Outcome for young children newly diagnosed with ependymoma, treated with intensive induction chemotherapy followed by myeloablative chemotherapy and autologous stem cell rescue
Pediatric Blood & Cancer
Stergios Zacharoulis, Adam Levy, Susan N. Chi, Sharon Gardner, Marc Rosenblum, Douglas C. Miller, Ira Dunkel, Blanca Diez, Richard Sposto, Lingyun Ji, Shahab Asgharzadeh, Juliette Hukin, Jean Belasco, Ronald Dubowy, Stewart Kellie, Amanda Termuhlen, Jonathan Finlay
DOI: 10.1002/pbc.20935
2007

Concurrent carbogen and radiation therapy in children with high-risk brainstem gliomas
Pediatric Blood & Cancer
C. Aquino-Parsons, J. Hukin, A. Green
DOI: 10.1002/pbc.21057
2007

Outcome of secondary high-grade glioma in children previously treated for a malignant condition: A study of the Canadian Pediatric Brain Tumour Consortium
Radiotherapy and Oncology
Anne-Sophie Carret, Uri Tabori, Bruce Crooks, Juliette Hukin, Isaac Odame, Donna L. Johnston, Daniel L. Keene, Carolyn Freeman, Eric Bouffet
DOI: 10.1016/j.radonc.2006.08.005
10/2006

Distinctive clinical course and pattern of relapse in adolescents with medulloblastoma
International Journal of Radiation Oncology*Biology*Physics
Uri Tabori, Lillian Sung, Juliette Hukin, Normand Laperriere, Bruce Crooks, Anne-Sophie Carret, Mariana Silva, Isaac Odame, Chris Mpofu, Douglas Strother, Beverly Wilson, Yvan Samson, Eric Bouffet
DOI: 10.1016/j.ijrobp.2005.07.962
02/2006

The causes and timing of death of craniopharyngiomas patients diagnosed before the age of 17 years
Pediatric Blood & Cancer
10/2005

Asynchronous burst-suppression in a child with callosal Ki-1 anaplastic large cell lymphoma.
Neurology
Hukin J, Davey A, Wong P, Hendson G, Aquino-Parsons C, Wu J, Sargent M
DOI: 10.1212/01.wnl.0000176070.34107.f6
PubMed: 16186544
09/2005

Childhood craniopharyngioma: Vancouver experience
Child's Nervous System
Juliette Hukin, Johann Visser, Michael Sargent, Karen Goddard, Chris Fryer, Paul Steinbok
DOI: 10.1007/s00381-005-1220-7
06/2005

Medulloblastoma in the second decade of life: A specific group with respect to toxicity and managementA Canadian Pediatric Brain Tumor Consortium Study
Cancer
Uri Tabori, Lillian Sung, Juliette Hukin, Normand Laperriere, Bruce Crooks, Anne-Sophie Carret, Mariana Silva, Isaac Odame, Chris Mpofu, Douglas Strother, Beverly Wilson, Yvan Samson, Eric Bouffet, Canadian Pediatric Brain Tumor Consortium
DOI: 10.1002/cncr.21003
2005

Malaysian Siblings with Friedreich Ataxia and Chorea: A Novel Deletion in the Frataxin Gene
The Canadian Journal of Neurological Sciences
Siân D. Spacey, Blazej I. Szczygielski, Sean P. Young, Juliette Hukin, Kathy Selby, Terrance P. Snutch
DOI: 10.1017/s0317167100003498
08/2004

Leptomeningeal dissemination at diagnosis of pediatric low-gradeneuroepithelial tumors
Neuro-Oncology
Juliette Hukin, Joao Siffert, Henry Cohen, Linda Velasquez, David Zagzag, Jeffrey Allen
DOI: 10.1215/s1152851702000297
07/2003

Leptomeningeal dissemination in children with progressive low-grade neuroepithelial tumors
Neuro-Oncology
Juliette Hukin, Joao Siffert, Linda Velasquez, David Zagzag, Jeffrey Allen
DOI: 10.1215/s1522851701000680
10/2002

Tenascin-C promotes microvascular cell migration and phosphorylation of focal adhesion kinase.
Cancer research
Zagzag D, Shiff B, Jallo GI, Greco MA, Blanco C, Cohen H, Hukin J, Allen JC, Friedlander DR
PubMed: 11980665
05/2002

Hyperbaric oxygen therapy for cerebral palsy: two complications of treatment.
Pediatrics
Nuthall G, Seear M, Lepawsky M, Wensley D, Skippen P, Hukin J
DOI: 10.1542/peds.106.6.e80
PubMed: 11099623
12/2000

Intratumoral Therapy with Bleomycin for Cystic Craniopharyngiomas in Children
Pediatric Neurosurgery
Walter J. Hader, Paul Steinbok, Juliette Hukin, Chris Fryer
DOI: 10.1159/000055955
2000

Brain Tumours
Primary Pediatric Care, 4th Edition
03/1999

Encephalopathy complicating Henoch-Schönlein purpura: reversible MRI changes.
Pediatric neurology
Woolfenden AR, Hukin J, Poskitt KJ, Connolly MB
DOI: 10.1016/s0887-8994(98)00027-7
PubMed: 9682892
07/1998

Case-control study of primary human herpesvirus 6 infection in children with febrile seizures.
Pediatrics
Hukin J, Farrell K, MacWilliam LM, Colbourne M, Waida E, Tan R, Mroz L, Thomas E
DOI: 10.1542/peds.101.2.e3
PubMed: 9445513
02/1998

Treatment of Intracranial Ependymoma by Surgery Alone
Pediatric Neurosurgery
Juliette Hukin, Fred Epstein, Dan Lefton, Jeffrey Allen
DOI: 10.1159/000028683
1998

Clinical Manifestations of Childhood Ependymoma:A Multitude of Syndromes
Pediatric Neurosurgery
Jeffrey C. Allen, Joao Siffert, Juliette Hukin
DOI: 10.1159/000028619
1998

Acute Swelling of the Cerebellum in Childhood
Journal of Child Neurology
Juliette Hukin, Douglas D. Cochrane, John U. Crichton
DOI: 10.1177/088307389701200411
06/1997

Basal ganglia infarction associated with HHV-6 infection.
Archives of Disease in Childhood
Webb DW, Bjornson BH, Sargent MA, Hukin J, Thomas EE
DOI: 10.1136/adc.76.4.362
PubMed: 9166034
04/1997

Reye syndrome associated with subclinical varicella zoster virus and influenza a infection
Pediatric Neurology
Juliette Hukin, Anne K. Junker, Eva E. Thomas, Kevin Farrell
DOI: 10.1016/0887-8994(93)90050-m
03/1993

Research

Headstart III
Earlier generations of multi-center "Baby" protocols have demonstrated the feasibility of chemotherapy-only strategies for young children with newly diagnosed malignant brain tumors. The disease-free survivals attained with these regimens, however, were disappointing. The "Head Start I and II" studies demonstrated generally superior outcome for patients with medulloblastoma, other PNET and ependymoma than other such studies.

The primary aim of Headstart III is to determine the two year event-free survival and overall survival from time of study enrollment, for young children with medulloblastoma and other malignant tumours with induction chemotherapy followed by consolidation with myeloablative chemotherapy and autologous hematopoietic cell rescue, with the aim of avoiding, deferring or reducing radiation therapy to the developing brain. Early results are demonstrating favourable outcomes for certain patient groups. We are working on the next study which will be Head Start IV.

Longitudinal study evaluating the recurrence rate in childhood ependymoma
The purpose of this study is to report on the incidence of early and late recurrences in childhood ependymoma, their management and the success thereof, and to evaluate long-term functional status.