My research interests involve areas directly relevant to the clinical practice of pediatric and perinatal pathology. I am particularly interested in the development of novel diagnostic and prognostic markers to improve management of common diseases in infants and children.


Quantifying Proximal Collecting Tubule Deficiency in Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Fetopathy
Pediatric and Developmental Pathology
Jessica Saunders and Allison Marie Callejas Salgado and Joseph Y Ting and Cherry Mammen and Jefferson Terry and Jonathan W Bush
DOI: 10.1177/10935266211018922

Prenatal Autoimmune Disease, Multisystem, Infantile Onset-like Phenotype and Proximal Renal Tubular Dysplasia Associated With STAT3 Mutation
Pediatric and Developmental Pathology
Jefferson Terry and Sylvie Langlois and Rosemarie Rupps and Harinder Gill
DOI: 10.1177/1093526619890734

Reproducibility of Grading in Chronic Intervillositis of Unknown Etiology
Pediatric and Developmental Pathology
Deidre Ongaro and Jefferson Terry
DOI: 10.1177/1093526619882522

Placental Expression of the Forelimb Patterning Transcription Factor MEIS2 in Trisomy 15
Fetal and Pediatric Pathology
Jennifer Pors and Tom Philipp and Jefferson Terry
DOI: 10.1080/15513815.2020.1732509

Altered levels of placental miR-338-3p and miR-518b are associated with acute chorioamnionitis and IL6 genotype
Chaini Konwar and Irina Manokhina and Jefferson Terry and Amy M. Inkster and Wendy P. Robinson
DOI: 10.1016/j.placenta.2019.05.009

Measles Lymphadenopathy in a Child With PFAPA Syndrome
Pediatric and Developmental Pathology
Jefferson Terry and Kelly Brown and Joanne Hiebert and Ghada N Al-Rawahi and J Paul Moxham and Mel Krajden and Agatha N Jassem and Lori Tucker
DOI: 10.1177/1093526617727970

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
Clinical Immunology
Robert J. Ragotte and Anita Dhanrajani and Julian Pleydell-Pearce and Kate L. Del Bel and Maja Tarailo-Graovac and Clara van Karnebeek and Jefferson Terry and Christof Senger and Margaret L. McKinnon and Michael Seear and Julie S. Prendiville and Lori B. Tucker and Kristin Houghton and David A. Cabral and Jaime Guzman and Ross E. Petty and Kelly L. Brown and Jenny Tekano and John Wu and Kimberly A. Morishita and Stuart E. Turvey
DOI: 10.1016/j.clim.2016.12.006

Shear wave absolute vibro-elastography of the placenta
Jeffrey Abeysekera and Manyou Ma and Mehran Pesteie and Jefferson Terry and Denise Pugash and Jennifer Hutcheon and Chantal Mayer and Septimiu Salcudean and Lutz Lampe and Robert Rohling
DOI: 10.1016/j.placenta.2016.06.081

Overlap chronic placental inflammation is associated with a unique gene expression pattern
DOI: 10.1371/journal.pone.0133738

Renal cell carcinoma with Xp 11.2 translocation as a second tumor in a long-term survivor of advanced neuroblastoma
Pediatric Hematology and Oncology
DOI: 10.3109/08880018.2014.979457

Vaginal Yolk Sac Tumor in an Infant: A Case Report and Literature Review of the Last 30 Years
Journal of Pediatric Hematology/Oncology
DOI: 10.1097/MPH.0000000000000325

Microsatellite Genotyping to Distinguish Somatic ß-HCG Secreting Carcinoma from Epithelioid Trophoblastic Tumor.
Brett MA and Sur M and Daya D and Terry J and Lytwyn A
DOI: 10.1155/2015/971970
PubMed: 25960907

Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression
DOI: 10.1182/blood-2014-06-581173

Fetal autopsy findings of cardiofaciocutaneous syndrome with a unique BRAF mutation
Pediatric and Developmental Pathology
DOI: 10.2350/13-08-1365-CR.1

Frozen section of placental membranes and umbilical cord: An aid to early postpartum diagnosis of intra-amniotic infection
American Journal of Clinical Pathology

BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate.
Bates SV and Lakshmanan A and Green AL and Terry J and Badalian-Very G and Rollins BJ and Fleck P and Aslam M and Degar BA
DOI: 10.1055/s-0033-1338168
PubMed: 24147236

Prenatal and pathologic features of aorto-left ventricular tunnel causing fetal hydrops and intrauterine demise
Pediatric and Developmental Pathology
DOI: 10.2350/12-10-1264-CR.1

Congenital langerhans cell histiocytosis with placental involvement
Pediatric and Developmental Pathology
DOI: 10.2350/12-11-1277-CR.1

Skin lesions and lung cysts in a neonate
Journal of Pediatrics
DOI: 10.1016/j.jpeds.2012.01.048

Immunohistochemical expression of CRX in extracranial malignant small round cell tumors
American Journal of Surgical Pathology
DOI: 10.1097/PAS.0b013e3182601d84

Immunohistochemical expression of neurotrophic tyrosine kinase receptors 1 and 2 in lung carcinoma: Potential discriminators between squamous and nonsquamous subtypes
Archives of Pathology and Laboratory Medicine

Expression of CD133 in synovial sarcoma
Applied Immunohistochemistry and Molecular Morphology
DOI: 10.1097/PAI.0b013e3181b77451

Canadian external quality assurance program for breast cancer biomarkers
Applied Immunohistochemistry and Molecular Morphology
DOI: 10.1097/PAI.0b013e3181e2de01

Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors
Genome Biology
DOI: 10.1186/gb-2010-11-8-r82

Optimal immunohistochemical markers for distinguishing lung adenocarcinomas from squamous cell carcinomas in small tumor samples
American Journal of Surgical Pathology
DOI: 10.1097/PAS.0b013e3181f7dae3

Implementation of a Canadian external quality assurance program for breast cancer biomarkers: An initiative of Canadian Quality Control in Immunohistochemistry (cIQc) and Canadian Association of Pathologists (CAP) national standards committee/immunohistochemistry
Applied Immunohistochemistry and Molecular Morphology
DOI: 10.1097/PAI.0b013e31819adacf

TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies
American Journal of Surgical Pathology
DOI: 10.1097/01.pas.0000213330.71745.39

Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models
Clinical Cancer Research
DOI: 10.1158/1078-0432.CCR-05-0398

Fluorescence in situ hybridization for the detection of t(X;18)(p11.2;q11.2) in a synovial sarcoma tissue microarray using a breakapart-style probe
Diagnostic Molecular Pathology
DOI: 10.1097/01.pas.0000155021.80213.c9


Current Projects
I am currently working towards identifying biomarkers which could ultimately lead to the development of a test for early diagnosis of amniotic fluid infection syndrome (AFI). AFI involves acute inflammation of placental tissue surrounding the fetus typically and leads to preterm labor with significant risk of adverse health complications and mortality. Early detection may improve outcome.

The role of bacterial triggers in the pathogenesis of Crohn's disease is another area of interest and I am presently developing an in situ assay for identification of potential trigger organisms in archival gastrointestinal tissue biopsies.

I am also involved in a collaborative study investigating the application of a novel ultrasonography technique to improve intrauterine detection of placental lesions.


2015, Clinical and Translational Research Seed Grant, Child and Family Research Centre

2015, Pathology and Laboratory Medicine Microgrant, BC Children's and Women's Hospital

2015, Young Investigator Research Grant, Society for Pediatric Pathology

Honours & Awards

2009, Annual Research Symposium, 1st Place, UBC Department of Pathology & Lab Medicine

2011, Lotte Strauss Prize, Society for Pediatric Pathology

2009, Trainee Research Award, Pulmanry Pathology Pathology Society

Research Group Members

Michelle Dittrick, Clinical Research Program Manager