My research interests involve areas directly relevant to the clinical practice of pediatric and perinatal pathology. I am particularly interested in the development of novel diagnostic and prognostic markers to improve management of common diseases in infants and children.


Measles Lymphadenopathy in a Child With PFAPA Syndrome
Pediatric and Developmental Pathology
Jefferson Terry, Kelly Brown, Joanne Hiebert, Ghada N Al-Rawahi, J Paul Moxham, Mel Krajden, Agatha N Jassem, Lori Tucker
DOI: 10.1177/1093526617727970

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
Clinical Immunology
Robert J. Ragotte, Anita Dhanrajani, Julian Pleydell-Pearce, Kate L. Del Bel, Maja Tarailo-Graovac, Clara van Karnebeek, Jefferson Terry, Christof Senger, Margaret L. McKinnon, Michael Seear, Julie S. Prendiville, Lori B. Tucker, Kristin Houghton, David A. Cabral, Jaime Guzman, Ross E. Petty, Kelly L. Brown, Jenny Tekano, John Wu, Kimberly A. Morishita, Stuart E. Turvey
DOI: 10.1016/j.clim.2016.12.006

Shear wave absolute vibro-elastography of the placenta
Jeffrey Abeysekera, Manyou Ma, Mehran Pesteie, Jefferson Terry, Denise Pugash, Jennifer Hutcheon, Chantal Mayer, Septimiu Salcudean, Lutz Lampe, Robert Rohling
DOI: 10.1016/j.placenta.2016.06.081

Vaginal Yolk Sac Tumor in an Infant: A Case Report and Literature Review of the Last 30 Years
Journal of Pediatric Hematology/Oncology
Bhatt, M.D. and Braga, L.H. and Stein, N. and Terry, J. and Portwine, C.
DOI: 10.1097/MPH.0000000000000325

Overlap chronic placental inflammation is associated with a unique gene expression pattern
Raman, K. and Wang, H. and Troncone, M.J. and Khan, W.I. and Pare, G. and Terry, J.
DOI: 10.1371/journal.pone.0133738

Microsatellite Genotyping to Distinguish Somatic ß-HCG Secreting Carcinoma from Epithelioid Trophoblastic Tumor.
Brett MA, Sur M, Daya D, Terry J, Lytwyn A
DOI: 10.1155/2015/971970
PubMed: 25960907

Renal cell carcinoma with Xp 11.2 translocation as a second tumor in a long-term survivor of advanced neuroblastoma
Pediatric Hematology and Oncology
Al-Mashaikhi, N. and Yang, J. and Terry, J. and Barr, R.
DOI: 10.3109/08880018.2014.979457

Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression
Beer, P.A. and Knapp, D.J.H.F. and Miller, P.H. and Kannan, N. and Sloma, I. and Heel, K. and Babovic, S. and Bulaeva, E. and Rabu, G. and Terry, J. and Druker, B.J. and Loriaux, M.M. and Loeb, K.R. and Radich, J.P. and Erber, W.N. and Eaves, C.J.
DOI: 10.1182/blood-2014-06-581173

Fetal autopsy findings of cardiofaciocutaneous syndrome with a unique BRAF mutation
Pediatric and Developmental Pathology
Terry, J. and Rauen, K.A. and Nowaczyk, M.J.M.
DOI: 10.2350/13-08-1365-CR.1

Frozen section of placental membranes and umbilical cord: An aid to early postpartum diagnosis of intra-amniotic infection
American Journal of Clinical Pathology
Mahe, E. and Hamid, J. and Terry, J. and Jansen, J.W. and Bourgeois, J. and Arredondo-Marin, J.

BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate.
Bates SV, Lakshmanan A, Green AL, Terry J, Badalian-Very G, Rollins BJ, Fleck P, Aslam M, Degar BA
DOI: 10.1055/s-0033-1338168
PubMed: 24147236

Congenital langerhans cell histiocytosis with placental involvement
Pediatric and Developmental Pathology
Terry, J. and Pluchinotta, F.R. and Sanders, S.P. and Vergilio, J.-A. and Hyde, S.R. and Boyd, T.K.
DOI: 10.2350/12-11-1277-CR.1

Prenatal and pathologic features of aorto-left ventricular tunnel causing fetal hydrops and intrauterine demise
Pediatric and Developmental Pathology
Terry, J. and Tapas, M. and Nowaczyk, M.J.M.
DOI: 10.2350/12-10-1264-CR.1

Immunohistochemical expression of CRX in extracranial malignant small round cell tumors
American Journal of Surgical Pathology
Terry, J. and Calicchio, M.L. and Rodriguez-Galindo, C. and Perez-Atayde, A.R.
DOI: 10.1097/PAS.0b013e3182601d84

Skin lesions and lung cysts in a neonate
Journal of Pediatrics
Forester, C.M. and Terry, J. and Lee, E.Y. and Simoneau, T. and Haver, K.
DOI: 10.1016/j.jpeds.2012.01.048

Immunohistochemical expression of neurotrophic tyrosine kinase receptors 1 and 2 in lung carcinoma: Potential discriminators between squamous and nonsquamous subtypes
Archives of Pathology and Laboratory Medicine
Terry, J. and De Luca, A. and Leung, S. and Peacock, G. and Wang, Y. and Elliot, M. and Huntsman, D.

Expression of CD133 in synovial sarcoma
Applied Immunohistochemistry and Molecular Morphology
Terry, J. and Nielsen, T.
DOI: 10.1097/PAI.0b013e3181b77451

Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors
Genome Biology
Jones, S.J.M. and Laskin, J. and Li, Y.Y. and Griffith, O.L. and An, J. and Bilenky, M. and Butterfield, Y.S. and Cezard, T. and Chuah, E. and Corbett, R. and Fejes, A. and Griffith, M. and Yee, J. and Martin, M. and Mayo, M. and Melnyk, N. and Morin, R.D. and Pugh, T.J. and Severson, T. and Shah, S.P. and Sutcliffe, M. and Tam, A. and Terry, J. and Thiessen, N. and Thomson, T. and Varhol, R. and Zeng, T. and Zhao, Y. and Moore, R.A. and Huntsman, D.G. and Birol, I. and Hirst, M. and Holt, R.A. and Marra, M.A.
DOI: 10.1186/gb-2010-11-8-r82

Canadian external quality assurance program for breast cancer biomarkers
Applied Immunohistochemistry and Molecular Morphology
Terry, J. and Torlakovic, E. and Trotter, M. and Garratt, J. and Barnes, P. and Gown, A. and Pettigrew, N. and Gilks, C.B.
DOI: 10.1097/PAI.0b013e3181e2de01

Optimal immunohistochemical markers for distinguishing lung adenocarcinomas from squamous cell carcinomas in small tumor samples
American Journal of Surgical Pathology
Terry, J. and Leung, S. and Laskin, J. and Leslie, K.O. and Gown, A.M. and Ionescu, D.N.
DOI: 10.1097/PAS.0b013e3181f7dae3

Implementation of a Canadian external quality assurance program for breast cancer biomarkers: An initiative of Canadian Quality Control in Immunohistochemistry (cIQc) and Canadian Association of Pathologists (CAP) national standards committee/immunohistochemistry
Applied Immunohistochemistry and Molecular Morphology
Terry, J., Torlakovic, E.E., Garratt, J., Miller, D., Köbel, M., Cooper, J., Bahzad, S., Pilavdzic, D., O'Malley, F., O'Brien, A.E., SenGupta, S., Alport, E., Têtu, B., Knight, B., Pettigrew, N.M., Berendt, R., Wolber, R., Trotter, M.J., Riddell, R.H., Gaboury, L., Elms, F., Magliocco, A., Barnes, P., Gown, A.M., Gilks, C.B.
DOI: 10.1097/PAI.0b013e31819adacf

TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies
American Journal of Surgical Pathology
Terry, J. and Saito, T. and Subramanian, S. and Ruttan, C. and Antonescu, C.R. and Goldblum, J.R. and Downs-Kelly, E. and Corless, C.L. and Rubin, B.P. and Van De Rijn, M. and Ladanyi, M. and Nielsen, T.O.
DOI: 10.1097/01.pas.0000213330.71745.39

Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin prevents synovial sarcoma proliferation via apoptosis in in vitro models
Clinical Cancer Research
Terry, J. and Lubieniecka, J.M. and Kwan, W. and Liu, S. and Nielsen, T.O.
DOI: 10.1158/1078-0432.CCR-05-0398

Fluorescence in situ hybridization for the detection of t(X;18)(p11.2;q11.2) in a synovial sarcoma tissue microarray using a breakapart-style probe
Diagnostic Molecular Pathology
Terry, J. and Barry, T.S. and Horsman, D.E. and Hsu, F.D. and Gown, A.M. and Huntsman, D.G. and Nielsen, T.O.
DOI: 10.1097/01.pas.0000155021.80213.c9


Current Projects
I am currently working towards identifying biomarkers which could ultimately lead to the development of a test for early diagnosis of amniotic fluid infection syndrome (AFI). AFI involves acute inflammation of placental tissue surrounding the fetus typically and leads to preterm labor with significant risk of adverse health complications and mortality. Early detection may improve outcome.

The role of bacterial triggers in the pathogenesis of Crohn's disease is another area of interest and I am presently developing an in situ assay for identification of potential trigger organisms in archival gastrointestinal tissue biopsies.

I am also involved in a collaborative study investigating the application of a novel ultrasonography technique to improve intrauterine detection of placental lesions.


2015, Clinical and Translational Research Seed Grant, Child and Family Research Centre

2015, Pathology and Laboratory Medicine Microgrant, BC Children's and Women's Hospital

2015, Young Investigator Research Grant, Society for Pediatric Pathology

Honours & Awards

2009, Annual Research Symposium, 1st Place, UBC Department of Pathology & Lab Medicine

2011, Lotte Strauss Prize, Society for Pediatric Pathology

2009, Trainee Research Award, Pulmanry Pathology Pathology Society

Research Group Members

Michelle Dittrick, Clinical Research Program Manager
Vassilena Sharlandjieva