Overview

As a pediatric cardiologist with a specialist interest in heart function and transplant medicine I am interested in disease processes and management of children with end stage heart failure and pediatric heart transplantation. Specifically I am interested in the long term follow up of these children. I have a long standing interest in exercise physiology and quality of life especially in children following heart transplant. I am also interested in the autonomic nervous system and the benefit of exercise in children with dysautonomia.

Publications

Exercise and the multidisciplinary holistic approach to adolescent dysautonomia.
Armstrong KR, De Souza AM, Sneddon PL, Potts JE, Claydon VE, Sanatani S
DOI: 10.1111/apa.13750
PubMed: 28112424
04/2017

Peritoneal-pericardial communication in an adolescent on peritoneal dialysis.
Teoh CW, Nadel H, Armstrong K, Harris KC, White CT
DOI: 10.1007/s00467-015-3206-3
PubMed: 26386589
01/2016

Childhood obesity, arterial stiffness, and prevalence and treatment of hypertension.
Armstrong KR, Cote AT, Devlin AM, Harris KC
DOI: 10.1007/s11936-014-0339-9
PubMed: 25248796
11/2014

New-onset migraine following closure of atrial septal defects in children.
Armstrong K, O'Mahony O, Farah L, Webb D
DOI: 10.1177/0333102414523341
PubMed: 24554622
10/2014

Cardiovascular dysfunction in infants with neonatal encephalopathy.
Armstrong K, Franklin O, Sweetman D, Molloy EJ
DOI: 10.1136/adc.2011.214205
PubMed: 21798875
04/2012

Cardiac biomarkers in neonatal hypoxic ischaemia.
Sweetman D, Armstrong K, Murphy JF, Molloy EJ
DOI: 10.1111/j.1651-2227.2011.02539.x
PubMed: 22118561
04/2012

Life and death decisions for incompetent patients: determining best interests--the Irish perspective.
Armstrong K, Ryan CA, Hawkes CP, Janvier A, Dempsey EM
DOI: 10.1111/j.1651-2227.2010.02084.x
PubMed: 21070357
04/2011

Benchmarking care for very low birthweight infants in Ireland and Northern Ireland.
Murphy BP, Armstrong K, Ryan CA, Jenkins JG
DOI: 10.1136/adc.2009.160002
PubMed: 19723619
01/2010

Fetal antecedents of male factor sub-fertility: how important is birthweight?
Ozturk O, Armstrong K, Bhattacharya S, Templeton A
DOI: 10.1093/humrep/16.10.2238
PubMed: 11574523
10/2001

Research

Current Projects
As part of my Heart Function research to date I sought to determine whether the existing Adult Hypertrophic Cardiomyopathy (HCM) Calculator to Predict Risk of Sudden cardiac death could be applied directly to the HCM Pediatric population at the Hospital for Sick Children in Toronto. Results showed that this calculator allowed us to risk stratify these patients, which we presented at AHA in November 2016. Our current project is to participate in a multi centre retrospective study across North America to explore this further with the hope of being able to risk stratify and predict which of our patients with Hypertophic cardiomyopathy are at risk of having a sudden cardiac event, and in whom would benefit from early intervention such as implantable cardioverter defibrillator (ICD) insertion.

We recently completed a study on the effect of an 8-week body weight exercise program on the quality of life in adolescents with dysautonomia. We showed a dramatic effect of exercise on the quality of life of these children and this research will be ongoing through the newly established Dysautonomia Clinic.

Our transplant team is involved in multiple studies on the physical health, exercise capacity, quality of life, and overall long-term health in pediatric transplant recipients. Coronary Allograft Vasculopathy (CAV) is one of the leading causes of death in pediatric transplant patients. To date, there is no clear way to detect CAV in these patients. One of my research focuses will be to look at the early detection of CAV in pediatric transplant patients.

Grants

iACT Clinical Investigator Trainee Synergy Grant

Honours & Awards

Child &Family Research Institute Outstanding Achievement by a Clinical Sub-specialty Resident or Fellow 2015

ITCC award for Cardiovascular Research Excellence in Pediatric Cardiology 2015

Laura McRae Award: Department of Pediatrics, BC Children’s Hospital Subspecialty Resident/Fellow Award for Excellence in Pediatric Medicine 2015

1st prize: Irish Pediatric Association Gold Medal, Belfast April 2012. National award for research at annual IPA meeting

1st prize: National Children’s Research Centre Open Day, May 2012. National award for Trainees involved in clinical research

Research Group Members

Jennifer Chuon
Anmar Batawi
Claire Galvin, Masters Student
Hajir AdlGolchin, Research Staff