My research encompasses advanced imaging techniques as they apply to children. Prior projects encompassed imaging of heart, lung and airway problems in children.
Publications
A subset of image-defined risk factors predict completeness of resection in children with high-risk neuroblastoma: An international multicenter study Pediatric Blood and Cancer DOI: 10.1002/pbc.31218 2024
Determining normal values for lower trachea and bronchi size in children by computed tomography (CT) Pediatric Pulmonology Chalwadi, U.K. and Swamy, N. and Agarwal, A. and Gauss, C.H. and Greenberg, S.B. and Lyons, K.A. DOI: 10.1002/ppul.25536 2021
A term neonate with cyanosis with crying Breathe Pertzborn, M.C. and Renno, M.S. and Lyons, K. and Fett, J. and Baird, C.W. and Agarwal, A. DOI: 10.1183/20734735.0097-2021 2021
The utility of pet/mri in pediatric malignancies Applied Radiology Lyons, K. and Sher, A. and Orth, R. and Seghers, V. 2018
Assessment of primary site response in children with high-risk neuroblastoma: An international multicenter study Journal of Clinical Oncology Bagatell, R. and McHugh, K. and Naranjo, A. and Van Ryn, C. and Kirby, C. and Brock, P. and Lyons, K.A. and States, L.J. and Rojas, Y. and Miller, A. and Volchenboum, S.L. and Simon, T. and Krug, B. and Sarnacki, S. and Valteau-Couanet, D. and Von Schweinitz, D. and Kammer, B. and Granata, C. and Pio, L. and Park, J.R. and Nuchtern, J. DOI: 10.1200/JCO.2015.63.2042 2016
The optimal timing of surgical resection in high-risk neuroblastoma Journal of Pediatric Surgery Rojas, Y. and Jaramillo, S. and Lyons, K. and Mahmood, N. and Wu, M.-F. and Liu, H. and Vasudevan, S.A. and Guillerman, R.P. and Louis, C.U. and Russell, H.V. and Nuchtern, J.G. and Kim, E.S. DOI: 10.1016/j.jpedsurg.2016.05.021 2016
Body MR angiography in children: how we do it Pediatric Radiology Krishnamurthy, R. and Malone, L.D. and Lyons, K. and Ketwaroo, P. and Dodd, N. and Ashton, D. DOI: 10.1007/s00247-016-3614-y 2016
Current Role of Fetal Magnetic Resonance Imaging in Neurologic Anomalies Seminars in Ultrasound, CT and MRI Lyons, K. and Cassady, C. and Jones, J. and Paldino, M. and Mehollin-Ray, A. and Guimaraes, C. and Krishnamurthy, R. DOI: 10.1053/j.sult.2015.05.012 2015
Qualitative FDG PET image assessment using automated three-segment mr attenuation correction versus ct attenuation correction in a tertiary pediatric hospital: A prospective study American Journal of Roentgenology Lyons, K. and Seghers, V. and Williams, J.L. and Sorensen, J.I.L. and Paldino, M.J. and Krishnamurthy, R. and Rohren, E.M. DOI: 10.2214/AJR.14.14231 2015
Comparison of standardized uptake values in normal structures between PET/CT and PET/MRI in a tertiary pediatric hospital: A prospective study American Journal of Roentgenology Lyons, K. and Seghers, V. and Sorensen, J.I.L. and Zhang, W. and Paldino, M.J. and Krishnamurthy, R. and Rohren, E.M. DOI: 10.2214/AJR.15.14304 2015
Current Projects 1. Utility of dual energy CT in children; in particular as it pertains to lung perfusion in congenital heart disease. This is a retrospective study looking at patients that were imaged using dual energy CT that have pulmonary arterial disease.
2. Utility of hyperpolarized 129Xe functional pulmonary MRI in children with interstitial lung disease. This is a collaborative project with Dr. Jonathan Rayment.
A pan-Canadian team has developed a new way to quickly find personalized treatments for young cancer patients, by growing their tumours in chicken eggs and analyzing their proteins.
The team, led by researchers from BC Children’s Hospital Research Institute and the University of British Columbia, is the first in Canada to combine these two techniques to identify and test a drug for a young patient's tumour in time for their treatment.
Congratulations to the investigators and their teams who were awarded funding through the Canadian Institutes of Health Research (CIHR) Fall 2024 Project Grant competition!
The findings from a BCCHR study played a part in integrating the multiple breath washout test into recent recommendations to screen children for pulmonary chronic graft-versus-host disease, a lung complication that can affect children who undergo a bone marrow transplant.
New research published in Nature Communications, identifies a key molecule that might be critical for the development of stem cell-based therapies for treating type 1 diabetes.
Dr. Kirk Schultz, an investigator at BC Children’s Hospital Research Institute, has been awarded the 2024 Geoffrey L. Hammond Lectureship in recognition of his leadership and significant contributions to improving the health and well-being of children in British Columbia and around the world.
We believe there’s nothing we can’t do with your support. It can take years to turn scientific breakthrough into new interventions and treatments. Funding helps speed the pace of change. When given the resources, we can bring transformative therapies – and hope – out of the laboratory and into the clinic to save and improve children’s lives.