Identification of novel Adenosine Deaminase 2 gene variants and varied clinical phenotype in pediatric vasculitis.
Arthritis & rheumatology (Hoboken, N.J.)
Gibson KM and Morishita KA and Dancey P and Moorehead P and Drögemöller B and Han X and Graham J and Hancock RE and Foell D and Benseler S and Luqmani R and Yeung RSM and Shenoi S and PedVas investigators network
DOI: 10.1002/art.40913
PubMed: 31008556

Innate Control of Tissue-Reparative Human Regulatory T Cells.
Journal of immunology (Baltimore, Md. : 1950)
Lam AJ and MacDonald KN and Pesenacker AM and Juvet SC and Morishita KA and Bressler B and iGenoMed Consortium and Pan JG and Sidhu SS and Rioux JD and Levings MK
DOI: 10.4049/jimmunol.1801330
PubMed: 30850479

Predicting Which Children with Juvenile Idiopathic Arthritis Will Not Attain Early Remission with Conventional Treatment: Results from the ReACCh-Out Cohort.
The Journal of rheumatology
Guzman J and Henrey A and Loughin T and Berard RA and Shiff NJ and Jurencak R and Huber AM and Oen K and Gerhold K and Feldman BM and Scuccimarri R and Houghton K and Chédeville G and ReACCh-Out Investigators
DOI: 10.3899/jrheum.180456
PubMed: 30647178

Feasibility and safety of a 6-month exercise program to increase bone and muscle strength in children with juvenile idiopathic arthritis
Pediatric Rheumatology
DOI: 10.1186/s12969-018-0283-4

Prospective Determination of the Incidence and Risk Factors of New-Onset Uveitis in Juvenile Idiopathic Arthritis: The Research in Arthritis in Canadian Children Emphasizing Outcomes Cohort.
Arthritis care & research
Lee JJY and Duffy CM and Guzman J and Oen K and Barrowman N and Rosenberg AM and Shiff NJ and Boire G and Stringer E and Spiegel L and Morishita KA and Lang B and Reddy D and Huber AM and ReACCh-Out Investigators
DOI: 10.1002/acr.23783
PubMed: 30320957

Natural history and extracutaneous involvement of congenital morphea: Multicenter retrospective cohort study and literature review
Pediatric Dermatology
Mark Mansour and Carmen Liy Wong and Francesco Zulian and Suzanne Li and Kimberly Morishita and Eluen Ann Yeh and Katie Stewart and Ronald M. Laxer and Elena Pope
DOI: 10.1111/pde.13605

Trajectories of pain severity in juvenile idiopathic arthritis
DOI: 10.1097/j.pain.0000000000001064

Health-Related Quality of Life in an Inception Cohort of Children With Juvenile Idiopathic Arthritis: A Longitudinal Analysis
Arthritis Care & Research
DOI: 10.1002/acr.23236

Therapeutic Management of Pediatric Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis
Current Treatment Options in Rheumatology
Kimberly A. Morishita and Georgina Tiller and David A. Cabral
DOI: 10.1007/s40674-017-0077-8

Clinical practice variation and need for pediatric-specific treatment guidelines among rheumatologists caring for children with ANCA-associated vasculitis: an international clinician survey.
Pediatric rheumatology online journal
Westwell-Roper C and Lubieniecka JM and Brown KL and Morishita KA and Mammen C and Wagner-Weiner L and Yen E and Li SC and O'Neil KM and Lapidus SK and Brogan P and Cimaz R and for ARChiVe Investigators Network within the PedVas initiative
DOI: 10.1186/s12969-017-0191-z
PubMed: 28784150

Growth and weight gain in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort.
Pediatric rheumatology online journal
DOI: 10.1186/s12969-017-0196-7
PubMed: 28830457

Early Outcomes in Children With Antineutrophil Cytoplasmic Antibody-Associated Vasculitis.
Arthritis & rheumatology (Hoboken, N.J.)
Morishita KA and Moorthy LN and Lubieniecka JM and Twilt M and Yeung RSM and Toth MB and Shenoi S and Ristic G and Nielsen SM and Luqmani RA and Li SC and Lee T and Lawson EF and ARChiVe Investigators Network within the PedVas Initiative
DOI: 10.1002/art.40112
PubMed: 28371513

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
Clinical Immunology
Robert J. Ragotte and Anita Dhanrajani and Julian Pleydell-Pearce and Kate L. Del Bel and Maja Tarailo-Graovac and Clara van Karnebeek and Jefferson Terry and Christof Senger and Margaret L. McKinnon and Michael Seear and Julie S. Prendiville and Lori B. Tucker and Kristin Houghton and David A. Cabral and Jaime Guzman and Ross E. Petty and Kelly L. Brown and Jenny Tekano and John Wu and Kimberly A. Morishita and Stuart E. Turvey
DOI: 10.1016/j.clim.2016.12.006

Granulomatosis with Polyangiitis in Children
Pediatric Rheumatology
David A. Cabral and Kimberly Morishita
DOI: 10.1007/978-981-10-1750-6_36

Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study
Arthritis & Rheumatology
David A. Cabral and Debra L. Canter and Eyal Muscal and Kabita Nanda and Dawn M. Wahezi and Steven J. Spalding and Marinka Twilt and Susanne M. Benseler and Sarah Campillo and Sirirat Charuvanij and Paul Dancey and Barbara A. Eberhard and Melissa E. Elder and Aimee Hersh and Gloria C. Higgins and Adam M. Huber and Raju Khubchandani and Susan Kim and Marisa Klein-Gitelman and Mikhail M. Kostik and Erica F. Lawson and Tzielan Lee and Joanna M. Lubieniecka and Deborah McCurdy and Lakshmi N. Moorthy and Kimberly A. Morishita and Susan M. Nielsen and Kathleen M. O'Neil and Andreas Reiff and Goran Ristic and Angela B. Robinson and Angelyne Sarmiento and Susan Shenoi and Mary B. Toth and Heather A. Van Mater and Linda Wagner-Weiner and Jennifer E. Weiss and Andrew J. White and Rae S. M. Yeung and the ARChiVe Investigators Network within the PedVas Initiative
DOI: 10.1002/art.39729

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression
Journal of Clinical Investigation
Scott J. Patterson and Anne M. Pesenacker and Adele Y. Wang and Jana Gillies and Majid Mojibian and Kim Morishita and Rusung Tan and Timothy J. Kieffer and C. Bruce Verchere and Constadina Panagiotopoulos and Megan K. Levings
DOI: 10.1172/jci83987

Development of System-level Performance Measures for Evaluation of Models of Care for Inflammatory Arthritis in Canada.
The Journal of rheumatology
DOI: 10.3899/jrheum.150839
PubMed: 26773106

Antineutrophil Cytoplasmic Antibody Associated Vasculitis
Textbook of Pediatric Rheumatology
David A. Cabral and Kimberly Morishita
DOI: 10.1016/b978-0-323-24145-8.00036-3

The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases
Guzman J and Oen K and Tucker LB and Huber AM and Shiff N and Boire G and Scuccimarri R and Berard R and Tse SM and Morishita K and Stringer E and Johnson N and Levy DM and Duffy KW and ReACCh-Out investigators
DOI: 10.1136/annrheumdis-2014-205372
PubMed: 24842571

Pediatric vasculitis
Current Opinion in Rheumatology
Kimberly Morishita and Kelly Brown and David Cabral
DOI: 10.1097/bor.0000000000000203

The risk and nature of flares in juvenile idiopathic arthritis: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases
DOI: 10.1136/annrheumdis-2014-207164
PubMed: 25985972

Early Atlantoaxial Subluxation in Enthesitis-related Arthritis
The Journal of Rheumatology
DOI: 10.3899/jrheum.131206

Chylous Pericardial Effusion in Granulomatosis with Polyangiitis
Nicholas Larkins and Kevin C Harris and Kimberly Morishita and Douglas G Matsell
DOI: 10.1111/nep.12262

A13: The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh Out) Cohort: Prospective Determination of the Incidence of New Onset Uveitis in Juvenile Idiopathic Arthritis
Arthritis & Rheumatology
Karen N Watanabe Duffy and Jennifer Lee and Jaime Guzman and Nick Barrowman and Kimberly Morishita and Lynn R. Spiegel and Elizabeth Stringer and Michele Gibbon and Rae SM Yeung and Lori B. Tucker and Kiem Oen and Ciarán M. Duffy and ReACChOut Investigators
DOI: 10.1002/art.38424

The risk and nature of flares in juvenile idiopathic arthritis: results from the reACCh-Out cohort
Pediatric Rheumatology
Jaime Guzman and Kiem Oen and Adam M Huber and Gilles Boire and Karen Duffy and Roberta Berard and Natalie J Shiff and Deborah M Levy and Elizabeth Stringer and Kimberly Morishita and Rosie Scuccimarri and Lori B Tucker and Rae SM Yeung and Ciaran Duffy and ReACCh-Out Investigators
DOI: 10.1186/1546-0096-12-s1-o9

Severe Vocal Cord Dysfunction: An Unusual Complication of Juvenile Dermatomyositis
The Journal of Rheumatology
DOI: 10.3899/jrheum.121338

Do adult disease severity subclassifications predict use of cyclophosphamide in children with ANCA-associated vasculitis? An analysis of ARChiVe study treatment decisions.
The Journal of rheumatology
Morishita K and Guzman J and Chira P and Muscal E and Zeft A and Klein-Gitelman M and Uribe AG and Abramson L and Benseler SM and Eberhard A and Ede K and Hashkes PJ and Hersh AO and ARChiVe Investigators Network
DOI: 10.3899/jrheum.120299
PubMed: 22859342

Assessing the performance of the Birmingham Vasculitis Activity Score at diagnosis for children with antineutrophil cytoplasmic antibody-associated vasculitis in A Registry for Childhood Vasculitis (ARChiVe).
The Journal of rheumatology
Morishita K and Li SC and Muscal E and Spalding S and Guzman J and Uribe A and Abramson L and Baszis K and Benseler S and Bowyer S and Campillo S and Chira P and Hersh AO and Higgins G and ARChiVe Investigators Network
DOI: 10.3899/jrheum.111030
PubMed: 22337238

Familial Takayasu arteritis - a pediatric case and a review of the literature
Pediatric Rheumatology
Kimberly A Morishita and Karen Rosendahl and Paul A Brogan
DOI: 10.1186/1546-0096-9-6

Musculoskeletal manifestations of mucopolysaccharidoses
K. Morishita and R. E. Petty
DOI: 10.1093/rheumatology/ker397

Mortality in Wegener's granulomatosis: a bimodal pattern
R. Luqmani and R. Suppiah and C. J. Edwards and R. Phillip and J. Maskell and D. Culliford and D. Jayne and K. Morishita and N. Arden
DOI: 10.1093/rheumatology/keq351

Serious musculoskeletal infections in children receiving anti-tumor necrosis factor-a therapy: a case series
Clinical Rheumatology
Kimberly Morishita and Ross Petty and Robyn Cairns and Roxana Bolaria and David Cabral and Stuart Turvey
DOI: 10.1007/s10067-010-1410-x

Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.
The Journal of rheumatology
Ortiz-Alvarez O and Morishita K and Avery G and Green J and Petty RE and Tucker LB and Malleson PN and Cabral DA
PubMed: 15570658


The role of T regulatory (Treg) cells in control and remission of JIA.
This study is looking at Treg function in the blood and synovial fluid of children with JIA at different disease states (active, inactive on medications, inactive off medications). The study will evaluate whether there is dysregulation in Treg function that may predict who is in true remission and who may be at increased risk of disease flare.

Predictors of outcomes in pediatric ANCA associated vasculitis.
This study will build on the previous study listed above. Clinical characteristics at baseline will be evaluated as potential predictors of outcome and models will be built so see if a combination of features may better predict certain outcomes compared to individual baseline characteristics.

Early outcomes in pediatric antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV): A Pediatric Vasculitis Initiative (PedVas) Study.
This study reported on 6- and 12-month outcomes in 79 children with AAV. Outcomes included remission rates, relapse rates, medication usage, damage, and rates of dialysis dependence. This was the largest study to date reporting early outcomes in this group of patients.


Training Grants: Canada Graduate Scholarship Master's Award, CIHR, 2010-2011. $17,500. UBC Clinical Investigator Program, 2010-2011. $70,000.

Research Grants: Clinical Translational Research Seed Grant, CFRI, 2014-2015. $5000.

Honours & Awards

Future Leaders in Rheumatology Training (FLIRT) Program. Nominated by peers to participate in this 2-year program. Canadian Rheumatology Association. 2012-2014.

Graduate Entrance Scholarship, University of British Columbia, 2011.

Research Group Members

Angelyne Rivera, Research Manager , Research Manager