Therapeutic Management of Pediatric Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis
Current Treatment Options in Rheumatology
Kimberly A. Morishita, Georgina Tiller, David A. Cabral
DOI: 10.1007/s40674-017-0077-8

The importance of considering monogenic causes of autoimmunity: A somatic mutation in KRAS causing pediatric Rosai-Dorfman syndrome and systemic lupus erythematosus
Clinical Immunology
Robert J. Ragotte, Anita Dhanrajani, Julian Pleydell-Pearce, Kate L. Del Bel, Maja Tarailo-Graovac, Clara van Karnebeek, Jefferson Terry, Christof Senger, Margaret L. McKinnon, Michael Seear, Julie S. Prendiville, Lori B. Tucker, Kristin Houghton, David A. Cabral, Jaime Guzman, Ross E. Petty, Kelly L. Brown, Jenny Tekano, John Wu, Kimberly A. Morishita, Stuart E. Turvey
DOI: 10.1016/j.clim.2016.12.006

Granulomatosis with Polyangiitis in Children
Pediatric Rheumatology
David A. Cabral, Kimberly Morishita
DOI: 10.1007/978-981-10-1750-6_36

Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort StudyCLINICAL FEATURES OF MPA VERSUS GPA
Arthritis & Rheumatology
David A. Cabral, Debra L. Canter, Eyal Muscal, Kabita Nanda, Dawn M. Wahezi, Steven J. Spalding, Marinka Twilt, Susanne M. Benseler, Sarah Campillo, Sirirat Charuvanij, Paul Dancey, Barbara A. Eberhard, Melissa E. Elder, Aimee Hersh, Gloria C. Higgins, Adam M. Huber, Raju Khubchandani, Susan Kim, Marisa Klein-Gitelman, Mikhail M. Kostik, Erica F. Lawson, Tzielan Lee, Joanna M. Lubieniecka, Deborah McCurdy, Lakshmi N. Moorthy, Kimberly A. Morishita, Susan M. Nielsen, Kathleen M. O'Neil, Andreas Reiff, Goran Ristic, Angela B. Robinson, Angelyne Sarmiento, Susan Shenoi, Mary B. Toth, Heather A. Van Mater, Linda Wagner-Weiner, Jennifer E. Weiss, Andrew J. White, Rae S. M. Yeung, the ARChiVe Investigators Network within the PedVas Initiative
DOI: 10.1002/art.39729

T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression
Journal of Clinical Investigation
Scott J. Patterson, Anne M. Pesenacker, Adele Y. Wang, Jana Gillies, Majid Mojibian, Kim Morishita, Rusung Tan, Timothy J. Kieffer, C. Bruce Verchere, Constadina Panagiotopoulos, Megan K. Levings
DOI: 10.1172/jci83987

Antineutrophil Cytoplasmic Antibody Associated Vasculitis
Textbook of Pediatric Rheumatology
David A. Cabral, Kimberly Morishita
DOI: 10.1016/b978-0-323-24145-8.00036-3

The outcomes of juvenile idiopathic arthritis in children managed with contemporary treatments: results from the ReACCh-Out cohort.
Annals of the rheumatic diseases
Guzman J, Oen K, Tucker LB, Huber AM, Shiff N, Boire G, Scuccimarri R, Berard R, Tse SM, Morishita K, Stringer E, Johnson N, Levy DM, Duffy KW, ReACCh-Out investigators
DOI: 10.1136/annrheumdis-2014-205372
PubMed: 24842571

Pediatric vasculitisadvances in treatment
Current Opinion in Rheumatology
Kimberly Morishita, Kelly Brown, David Cabral
DOI: 10.1097/bor.0000000000000203

Early Atlantoaxial Subluxation in Enthesitis-related Arthritis
The Journal of Rheumatology
DOI: 10.3899/jrheum.131206

Chylous Pericardial Effusion in Granulomatosis with PolyangiitisCorrespondence
Nicholas Larkins, Kevin C Harris, Kimberly Morishita, Douglas G Matsell
DOI: 10.1111/nep.12262

A13: The Research in Arthritis in Canadian Children Emphasizing Outcomes (ReACCh Out) Cohort: Prospective Determination of the Incidence of New Onset Uveitis in Juvenile Idiopathic Arthritis
Arthritis & Rheumatology
Karen N Watanabe Duffy, Jennifer Lee, Jaime Guzman, Nick Barrowman, Kimberly Morishita, Lynn R. Spiegel, Elizabeth Stringer, Michele Gibbon, Rae SM Yeung, Lori B. Tucker, Kiem Oen, Ciarán M. Duffy, ReACChOut Investigators
DOI: 10.1002/art.38424

The risk and nature of flares in juvenile idiopathic arthritis: results from the reACCh-Out cohort
Pediatric Rheumatology
Jaime Guzman, Kiem Oen, Adam M Huber, Gilles Boire, Karen Duffy, Roberta Berard, Natalie J Shiff, Deborah M Levy, Elizabeth Stringer, Kimberly Morishita, Rosie Scuccimarri, Lori B Tucker, Rae SM Yeung, Ciaran Duffy, ReACCh-Out Investigators
DOI: 10.1186/1546-0096-12-s1-o9

Severe Vocal Cord Dysfunction: An Unusual Complication of Juvenile Dermatomyositis
The Journal of Rheumatology
DOI: 10.3899/jrheum.121338

Do adult disease severity subclassifications predict use of cyclophosphamide in children with ANCA-associated vasculitis? An analysis of ARChiVe study treatment decisions.
The Journal of rheumatology
Morishita K, Guzman J, Chira P, Muscal E, Zeft A, Klein-Gitelman M, Uribe AG, Abramson L, Benseler SM, Eberhard A, Ede K, Hashkes PJ, Hersh AO, ARChiVe Investigators Network
DOI: 10.3899/jrheum.120299
PubMed: 22859342

Assessing the performance of the Birmingham Vasculitis Activity Score at diagnosis for children with antineutrophil cytoplasmic antibody-associated vasculitis in A Registry for Childhood Vasculitis (ARChiVe).
The Journal of rheumatology
Morishita K, Li SC, Muscal E, Spalding S, Guzman J, Uribe A, Abramson L, Baszis K, Benseler S, Bowyer S, Campillo S, Chira P, Hersh AO, Higgins G, ARChiVe Investigators Network
DOI: 10.3899/jrheum.111030
PubMed: 22337238

Musculoskeletal manifestations of mucopolysaccharidoses
K. Morishita, R. E. Petty
DOI: 10.1093/rheumatology/ker397

Familial Takayasu arteritis - a pediatric case and a review of the literature
Pediatric Rheumatology
Kimberly A Morishita, Karen Rosendahl, Paul A Brogan
DOI: 10.1186/1546-0096-9-6

Mortality in Wegener's granulomatosis: a bimodal pattern
R. Luqmani, R. Suppiah, C. J. Edwards, R. Phillip, J. Maskell, D. Culliford, D. Jayne, K. Morishita, N. Arden
DOI: 10.1093/rheumatology/keq351

Serious musculoskeletal infections in children receiving anti-tumor necrosis factor-a therapy: a case series
Clinical Rheumatology
Kimberly Morishita, Ross Petty, Robyn Cairns, Roxana Bolaria, David Cabral, Stuart Turvey
DOI: 10.1007/s10067-010-1410-x

Guidelines for blood test monitoring of methotrexate toxicity in juvenile idiopathic arthritis.
The Journal of rheumatology
Ortiz-Alvarez O, Morishita K, Avery G, Green J, Petty RE, Tucker LB, Malleson PN, Cabral DA
PubMed: 15570658


The role of T regulatory (Treg) cells in control and remission of JIA.
This study is looking at Treg function in the blood and synovial fluid of children with JIA at different disease states (active, inactive on medications, inactive off medications). The study will evaluate whether there is dysregulation in Treg function that may predict who is in true remission and who may be at increased risk of disease flare.

Predictors of outcomes in pediatric ANCA associated vasculitis.
This study will build on the previous study listed above. Clinical characteristics at baseline will be evaluated as potential predictors of outcome and models will be built so see if a combination of features may better predict certain outcomes compared to individual baseline characteristics.

Early outcomes in pediatric antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV): A Pediatric Vasculitis Initiative (PedVas) Study.
This study reported on 6- and 12-month outcomes in 79 children with AAV. Outcomes included remission rates, relapse rates, medication usage, damage, and rates of dialysis dependence. This was the largest study to date reporting early outcomes in this group of patients.


Training Grants: Canada Graduate Scholarship Master's Award, CIHR, 2010-2011. $17,500. UBC Clinical Investigator Program, 2010-2011. $70,000.

Research Grants: Clinical Translational Research Seed Grant, CFRI, 2014-2015. $5000.

Honours & Awards

Future Leaders in Rheumatology Training (FLIRT) Program. Nominated by peers to participate in this 2-year program. Canadian Rheumatology Association. 2012-2014.

Graduate Entrance Scholarship, University of British Columbia, 2011.

Research Group Members

Angelyne Sarmiento, Research Manager