I am a pediatric respirologist with an interest in clinical research. I am particularly interested in studying rare diseases of the lungs and airways in children, and investigating patterns and determinants of these diseases within our population (epidemiology). Epidemiological research helps us to understand how many children have a specific disease and whether this number is changing over time, which can be used to shape health policy and ensure that affected children receive the care that they need.
I am currently the lead investigator of the British Paediatric Surveillance Unit national surveillance study of Pierre Robin sequence (PRS), a condition which can cause upper airway obstruction in early infancy. This study is investigating the number of babies born each year with PRS in the United Kingdom and Ireland, the types of breathing support that affected children need, and their health related outcomes at 1 year of age.
My other areas of research interest include the long-term respiratory health of children after organ transplantation and the use of continuous glucose monitoring devices for the diagnosis of cystic fibrosis related diabetes.
Acute Infections That Produce Upper Airway Obstruction
Kendig's Disorders of the Respiratory Tract in Children
Balfour-Lynn, I.M. and Wright, M.
Case of paediatric neuromuscular disease with a surprising clinical outcome: Time to challenge the dogma?
Wright, M. and Manzur, A. and Bush, A.
Epidemiology of Robin sequence with cleft palate in the East of Scotland between 2004 and 2013
Wright, M. and Mehendale, F. and Urquhart, D.S.
Habit-tic cough: Presentation and outcome with simple reassurance
Wright, M.F.A. and Balfour-Lynn, I.M.
Hypersensitivity reactions to intravenous antibiotics in cystic fibrosis
Paediatric Respiratory Reviews
Wright, M.F.A. and Bush, A. and Carr, S.B.
Investigation and management of the long-term ventilated premature infant
Early Human Development
Wright, M.F.A. and Wallis, C.
Quantifying fluctuation in glucose levels to identify early changes in glucose homeostasis in cystic fibrosis
Journal of Cystic Fibrosis
Brugha, R. and Wright, M. and Nolan, S. and Bridges, N. and Carr, S.B.
Paediatric femoral hernia - The diagnostic challenge
International Journal of Surgery
Wright, M.F.A. and Scollay, J.M. and McCabe, A.J. and Munro, F.D.
National surveillance study of Pierre Robin sequence in the United Kingdom and Republic of Ireland
A prospective population-based study investigating the birth prevalence of PRS across the UK, the prevalence and management of upper airway obstruction in affected infants, and their long-term outcomes in terms of upper airway obstruction, growth and neurodevelopment.
Long-term respiratory outcomes following childhood solid organ transplantation
A retrospective review of respiratory morbidity following heart, liver and kidney transplant in children followed by the BC Children's Hospital multi-organ transplant team.Grants
Sir Peter Tizard Research Bursary (Royal College of Paediatrics and Child Health, UK) national award recipient (2014)Honours & Awards
British Paediatric Respiratory Society travel award (2016)
Rare Diseases Foundation micro-grant award (2015)
European Respiratory Society award for best abstract in the field of Paediatric Respiratory Epidemiology (2014)Research Group Members
Kudrat Mundi, Flex Summer Research Student
Rescued from the rubbish bin: How the thymus could stop organ transplant rejection
Dr. Megan Levings has been a pioneer in the world of immunology. Now, her research on the thymus, often discarded during pediatric heart surgery, as a source of very specialized immune system could transform the field of organ transplantation. A world-first clinical trial is underway in Spain.