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Marie Wright
MRCPCH, MBChB, FRCPC, MD

Investigator, BC Children's Hospital
Physician, Division of Respiratory Medicine, BC Children's Hospital
Director, Home Tracheostomy and Ventilation (HTV) Program, BC Children's Hospital
Clinical Assistant Professor, Department of Pediatrics, University of British Columbia

I am a pediatric respirologist with an interest in clinical research and quality improvement, and director of the BCCH Home Tracheostomy and Ventilation (HTV) clinic.

My clinical work is based in the HTV, sleep, and rare lung diseases clinics, as well as inpatient care of babies and children with a wide range of acute and chronic respiratory disorders.

My postgraduate research studies (Doctor of Research, MD(Res), University College London / Great Ormond Street Institute of Child Health) focused on children born with Pierre Robin sequence, and how optimal health outcomes can be achieved through different approaches to management of airway obstruction.

My current main areas of research interest include respiratory management and long-term outcomes of children with neuromuscular disorders (including spinal muscular atrophy and Duchenne muscular dystrophy) and prematurity-related lung disease (bronchopulmonary dysplasia). Examples of my quality improvement work include delivering care to HTV patients outside of the Pediatric Intensive Care Unit and improving the transition of HTV patients from Pediatric to adult medical services.

I have expertise in a range of study methodologies including systematic reviews and meta-analysis, active surveillance studies and reporting card systems, prospective and retrospective observational studies, and qualitative research. I have also received formal training in quality improvement methodology through the PHSA Physician Quality Improvement training program (2022-23 cohort).

I am a strong advocate of collaborative and team-based research, and have led multi-center research studies both in Canada and the UK, as well as mentoring allied health colleagues, trainees and medical students who have a desire to participate in clinical research.

My passion for clinical research is based on a desire to better understand the causes and long-term outcomes of lung and airway diseases affecting children, particularly those that are rare, complex, or under-studied. My quality improvement work is perhaps even more rewarding because it enables us to identify barriers to delivering excellent clinical care and to quickly implement sustainable and patient-focused changes.

Academic Affiliations

  • Clinical Assistant Professor, , Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Childhood Diseases

Contact Information

Location

4480 Oak Street, Vancouver, British Columbia, Canada, V6H3N1

(604) 875-2345 ext. 6877

marie.wright@cw.bc.ca

Airway management in infants with Robin sequence in the United Kingdom and Ireland: A prospective population-based study

Pediatric Pulmonology

Marie Wright and Rachel L. Knowles and Mario Cortina-Borja and Sheila Javadpour and Felicity V. Mehendale and Don Urquhart

DOI: 10.1002/ppul.27140

06 / 2024

Global birth prevalence of Robin sequence in live-born infants: a systematic review and meta-analysis.

European respiratory review : an official journal of the European Respiratory Society

Wright M and Cortina-Borja M and Rachel Knowles and Don Urquhart

DOI: 10.1183/16000617.0133-2023 PubMed: 38056889

12 / 2023

Conservative and Surgical Modalities in the Management of Pediatric Parapneumonic Effusion and Empyema

CHEST

Clara Fernandez Elviro and Bryn Longcroft-Harris and Emily Allin and Leire Leache and Kellan Woo and Jeffrey N. Bone and Colleen Pawliuk and Jalal Tarabishi and Matthew Carwana and Marie Wright and Nassr Nama and Roshan A. Ananda and Priyadharshini Ramakrishnan and Tala J. Alhejazi and Alyssa Chen and Amin Sharifan and Mohamed M. Shawqi

DOI: 10.1016/j.chest.2023.06.010

11 / 2023

Epidemiology of Robin sequence in the UK and Ireland: an active surveillance study

Archives of Disease in Childhood

Marie FA Wright and Rachel L Knowles and Mario Cortina-Borja and Sheila Javadpour and Felicity V Mehendale and Donald S Urquhart

DOI: 10.1136/archdischild-2023-325556

09 / 2023

Hypersensitivity reactions to intravenous antibiotics in cystic fibrosis

Paediatric Respiratory Reviews

Wright, M.F.A. and Bush, A. and Carr, S.B.

DOI: 10.1016/j.prrv.2018.01.003

Long-term respiratory outcomes following solid organ transplantation in children: A retrospective cohort study

Pediatric Pulmonology

M. F. A. Wright and T. Blydt-Hansen and M. A. Chilvers

DOI: 10.1002/ppul.25968

09 / 2022

Quantifying fluctuation in glucose levels to identify early changes in glucose homeostasis in cystic fibrosis

Journal of Cystic Fibrosis

Brugha, R. and Wright, M. and Nolan, S. and Bridges, N. and Carr, S.B.

DOI: 10.1016/j.jcf.2017.12.004

Case of paediatric neuromuscular disease with a surprising clinical outcome: Time to challenge the dogma?

Thorax

Wright, M. and Manzur, A. and Bush, A.

DOI: 10.1136/thoraxjnl-2017-211058

Paediatric femoral hernia - The diagnostic challenge

International Journal of Surgery

Wright, M.F.A. and Scollay, J.M. and McCabe, A.J. and Munro, F.D.

DOI: 10.1016/j.ijsu.2011.05.004

Acute Infections That Produce Upper Airway Obstruction

Kendig's Disorders of the Respiratory Tract in Children

Balfour-Lynn, I.M. and Wright, M.

DOI: 10.1016/B978-0-323-44887-1.00023-7

Investigation and management of the long-term ventilated premature infant

Early Human Development

Wright, M.F.A. and Wallis, C.

DOI: 10.1016/j.earlhumdev.2018.08.015

Epidemiology of Robin sequence with cleft palate in the East of Scotland between 2004 and 2013

Pediatric Pulmonology

Wright, M. and Mehendale, F. and Urquhart, D.S.

DOI: 10.1002/ppul.24038

Habit-tic cough: Presentation and outcome with simple reassurance

Pediatric Pulmonology

Wright, M.F.A. and Balfour-Lynn, I.M.

DOI: 10.1002/ppul.23948

An infant with congenital respiratory insufficiency and diaphragmatic paralysis: A novel BICD2 phenotype?

American journal of medical genetics. Part A

Hui-Lin Chin and Huynh S and Ashkani J and Castaldo M and Katherine Dixon and Selby K and Shen Y and Wright M and Cornelius Boerkoel and Hendson G and Steven Jones

DOI: 10.1002/ajmg.a.62578 PubMed: 34825470

11 / 2021

Long term respiratory outcomes following solid organ transplantation in children: a retrospective cohort study.

Marie Wright and Mark Chilvers and Tom Blydt-Hansen

DOI: 10.22541/au.163255287.73643413/v1

09 / 2021

Conservative and surgical modalities in the management of paediatric parapneumonic effusion and empyema: a protocol for a living systematic review and network meta-analysis.

BMJ open

Emily Allin and Nassr Nama and Michael Irvine and Colleen Pawliuk and Wright M and Carwana M

DOI: 10.1136/bmjopen-2020-045010 PubMed: 33762243

03 / 2021

Continuous positive airway pressure for obstructive sleep apnea in children.

Canadian family physician Medecin de famille canadien

Wang JJ and Imamura T and Lee J and Wright M and Ran D. Goldman

DOI: 10.46747/cfp.670121 PubMed: 33483390

01 / 2021

Impact of an Integrated Framework on Care Transition of Infants with Medical Complexity

Complex Care Journal

Assessment and management of viral croup in children

Prescriber

Marie Wright and Andrew Bush

DOI: 10.1002/psb.1490

08 / 2016

Patient, caregiver, and healthcare provider experiences of transition from pediatric to adult services for users of home mechanical ventilation: a qualitative study and quality improvement project.

“The Right Care, in the Right Place, at the Right Time”: supporting children on home mechanical ventilation during hospital admission: an interdisciplinary quality improvement project

Respiratory health in children with Spinal Muscular Atrophy treated with disease modifying therapies

Studies underway involving respiratory and bulbar function in children with SMA who were treated with disease modifying therapies before and after the introduction of newborn screening in British Columbia (2022)

Use of home respiratory support for preterm infants with bronchopulmonary dysplasia in British Columbia

A retrospective cohort study reviewing management and long-term clinical outcomes (respiratory health, growth, neurodevelopment) of infants with bronchopulmonary dysplasia who were discharged from the NICU on home respiratory support (supplementary oxygen, non-invasive ventilation, tracheostomy ventilation) over a 10-year period.

National surveillance study of Pierre Robin sequence in the United Kingdom and Republic of Ireland

A prospective population-based study investigating the birth prevalence of PRS across the UK, the prevalence and management of upper airway obstruction in affected infants, and their long-term outcomes in terms of upper airway obstruction, growth and neurodevelopment.

Long-term respiratory outcomes following childhood solid organ transplantation

A retrospective review of respiratory morbidity following heart, liver and kidney transplant in children followed by the BC Children's Hospital multi-organ transplant team.

Grants

BCCHR Practice Based Research Program (2023)

MASES/ Doctors of BC Facility Engagement Initiative (2023)

MASES/ Doctors of BC Facility Engagement Initiative (2023)

Honours & Awards

UBC Department of Pediatrics, Resident Teacher of The Year (2024)

3rd International Robin Sequence Consensus Meeting Abstract Award (2022)

Sir Peter Tizard Research Bursary (Royal College of Paediatrics and Child Health, UK) national award recipient (2014)

British Paediatric Respiratory Society travel award (2016)

Rare Diseases Foundation micro-grant award (2015)

European Respiratory Society award for best abstract in the field of Paediatric Respiratory Epidemiology (2014)

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