- Overview
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Based on my interest in adherence research, socio-cultural aspects of medicine, child development and neurology I developed, in collaboration with medical anthropology and educational psychology, a comprehensive functional sleep/wake-behaviours assessment concept and began to transform physiological knowledge with questions of sleep health and management.
In collaboration with the Cognitive Systems Lab at UBC, I have developed a 'Virtual-Sleep-Lab' concept, where Videosomnography is used for screening 'visible' and 'recognizable' sleep disorders in children with neurodevelopmental and mental health disorders in their natural setting, at home. Based on this research, the Inter. RLS Consensus Group has included children with neurodevelopmental delay (NDD) in their recent Consensus Statement.
Our current research focuses on children with NDD, who often have a combination of voluntary and involuntary movements. These movements are associated with hyperactivity and hyper-/hypo-arousability in the wake state, and hypermotor-restlessness in the sleep state, all summarized as H-Behaviours. H-Behaviours occur across a spectrum of the most frequent developmental, neurologic and mental health conditions such as ADHD, Restless Legs Syndrome (RLS) or Willis-Ekbom Disease, tics, Tourette syndrome, anxiety, ASD and FASD. While the H-Behaviour associated movement patterns are very well described in children with ADHD, tics and Tourette syndrome, they are less so in RLS/WED. Additionally, they have not been clearly defined across age, different symptoms and presentations.
Targeting single aspects of such behaviours with pharmacological interventions (stimulants, anti-depressants, anti-psychotics) increases the likelihood for adverse drug reactions – usually these children/youth are trialed with multiple psychotropic substances. In order to reduce the epidemic of psychotropic substance use, we created an international clinical and technical research consortium. Clinician backgrounds include paediatrics, neurology, psychiatry, psychology, and occupational therapy, while technician backgrounds include computing, bio-mechanical engineering, and signal processing engineering, Most members joined at the 4th Conference of International Pediatric Sleep Association (IPSA - Taipei 2015) under the Video Working Group, which offers members a roof for collaborative action.
- Publications
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Sleep After Concussion: A Scoping Review of Sensor Technologies
Journal of Neurotrauma
DOI: 10.1089/neu.2023.0526
2024Staying vigilant about the sleep–wake states—is one question the whole story?
SLEEP Advances
DOI: 10.1093/sleepadvances/zpae024
2024Iron Deficiency and Sleep/Wake Behaviors: A Scoping Review of Clinical Practice Guidelines—How to Overcome the Current Conundrum?
Nutrients
DOI: 10.3390/nu16152559
2024Iron Deficiency and Restless Sleep/Wake Behaviors in Neurodevelopmental Disorders and Mental Health Conditions
Nutrients
DOI: 10.3390/nu16183064
2024Melatonin use in managing insomnia in children with autism and other neurogenetic disorders - An assessment by the international pediatric sleep association (IPSA)
Sleep Medicine
DOI: 10.1016/j.sleep.2024.04.008
2024Phenotyping sleep disturbances in ADHD and identifying harmonised outcome measures: A personalised precision medicine approach to disruptive behaviours
Somnologie
DOI: 10.1007/s11818-024-00473-4
2024An eHealth Program for Insomnia in Children With Neurodevelopmental Disorders (Better Nights, Better Days): Protocol for an Economic Evaluation of a Randomized Controlled Trial
JMIR Research Protocols
Xiao Yang Jia and Pantelis Andreou and Cary Brown and Evelyn Constantin and Roger Godbout and Ana Hanlon-Dearman and Osman Ipsiroglu and Graham Reid and Sarah Shea and Isabel M Smith and Jennifer D Zwicker and Shelly K Weiss and Penny Corkum
DOI: 10.2196/46735
09/2023An eHealth Program for Insomnia in Children With Neurodevelopmental Disorders (Better Nights, Better Days): Protocol for an Economic Evaluation of a Randomized Controlled Trial (Preprint)
Xiao Yang Jia and Pantelis Andreou and Cary Brown and Evelyn Constantin and Roger Godbout and Ana Hanlon-Dearman and Osman Ipsiroglu and Graham Reid and Sarah Shea and Isabel M Smith and Jennifer D Zwicker and Shelly K Weiss and Penny Corkum
DOI: 10.2196/preprints.46735
02/2023Optimizing the Better Nights, Better Days for Children with Neurodevelopmental Disorders program for large scale implementation
Frontiers in Sleep
DOI: 10.3389/frsle.2023.1158983
2023Editorial: Sleep, vigilance & disruptive behaviors
Frontiers in Psychiatry
DOI: 10.3389/fpsyt.2023.1230825
2023Social-ecological considerations informing a universal screening strategy for sleep health in the community
Frontiers in Psychiatry
DOI: 10.3389/fpsyt.2023.857717
2023Lessons from the COVID-19 Shutdown: the Waitlist Challenge & Insights in Overmedication Pathways
Sleep Medicine
O. Ipsiroglu and S. McWilliams and R. Boldut and J. Bhathella and D. Elbe and D. Wensley
DOI: 10.1016/j.sleep.2022.05.535
12/2022Lessons from the COVID-19 Shutdown: the Waitlist Challenge & Insights in Overmedication Pathways
Sleep medicine
Ipsiroglu O and McWilliams S and Boldut R and Bhathella J and Elbe D and Wensley D
07/2022Erratum to: Current developments in sleep research and sleep medicine: an assessment of the “Paediatrics” taskforce (Somnologie, (2022), 26, 3, (174-178), 10.1007/s11818-022-00383-3),Erratum zu: Aktuelle Entwicklungen in der Schlafforschung und Schlafmedizin – eine Einschätzung der AG „Pädiatrie“ (Somnologie, (2022), 26, 3, (174-178), 10.1007/s11818-022-00383-3)
Somnologie
Paditz, E. and Wiater, A. and Ipsiroglu, O. and Quante, M. and M{\"u}ller-Hagedorn, S. and Hoch, B. and Erler, T. and Mollin, J. and Schneider, B. and Poets, C.F.
DOI: 10.1007/s11818-022-00386-0
2022Revisiting the Concept of Vigilance
Frontiers in Psychiatry
Kl{\"o}sch, G. and Zeitlhofer, J. and Ipsiroglu, O.
DOI: 10.3389/fpsyt.2022.874757
2022Iron deficiency and common neurodevelopmental disorders—A scoping review
PLoS ONE
McWilliams, S. and Singh, I. and Leung, W. and Stockler, S. and Ipsiroglu, O.S.
DOI: 10.1371/journal.pone.0273819
2022Disruptive Behaviors and Intellectual Disability: Creating a New Script
Frontiers in Psychiatry
Chan, M.C.-H. and Campbell, M. and Beyzaei, N. and Stockler, S. and Ipsiroglu, O.S.
DOI: 10.3389/fpsyt.2022.851490
2022Behavioral sleep medicine—The need for harmonization of clinical best practice outcome measures in children and adolescents with intellectual or developmental disabilities and restless sleep
Frontiers in Psychiatry
Silvestri, R. and Ipsiroglu, O.S.
DOI: 10.3389/fpsyt.2022.1003019
2022Current developments in sleep research and sleep medicine: an assessment of the “Paediatrics” taskforce,Aktuelle Entwicklungen in der Schlafforschung und Schlafmedizin – eine Einschätzung der AG „Pädiatrie“
Somnologie
Paditz, E. and Wiater, A. and Ipsiroglu, O. and Quante, M. and M{\"u}ller-Hagedorn, S. and Hoch, B. and Erler, T. and Mollin, J. and Schneider, B. and Poets, C.F.
DOI: 10.1007/s11818-022-00383-3
2022Understanding patient characteristics and medication prescriptions in children with mental health and neurodevelopmental disorders referred to a sleep clinic—A quality improvement/quality assurance analysis
Frontiers in Psychiatry
Ipsiroglu, O.S. and Bhathella, J. and Boldut, R.P. and Elbe, D. and Hill, O. and Keys, E. and McWilliams, S. and Silvestri, R. and Wensley, D.F.
DOI: 10.3389/fpsyt.2022.878356
2022Sleep as an outcome measure in ADHD randomized controlled trials: A scoping review
Sleep Medicine Reviews
McWilliams, S. and Zhou, T. and Stockler, S. and Elbe, D. and Ipsiroglu, O.S.
DOI: 10.1016/j.smrv.2022.101613
2022Children's Sleep during COVID-19: How Sleep Influences Surviving and Thriving in Families
Journal of Pediatric Psychology
Mackenzie, N.E. and Keys, E. and Hall, W.A. and Gruber, R. and Smith, I.M. and Constantin, E. and Godbout, R. and Stremler, R. and Reid, G.J. and Hanlon-Dearman, A. and Brown, C.A. and Shea, S. and Weiss, S.K. and Ipsiroglu, O. and Witmans, M. and Chambers, C.T. and Andreou, P. and Begum, E. and Corkum, P.
DOI: 10.1093/jpepsy/jsab075
2021Fidgety Philip and the Suggested Clinical Immobilization Test: Annotation data for developing a machine learning algorithm
Data in Brief
Chan, M. and Tse, E.K. and Bao, S. and Berger, M. and Beyzaei, N. and Campbell, M. and Garn, H. and Hussaina, H. and Kloesch, G. and Kohn, B. and Kuzeljevic, B. and Lee, Y.J. and Maher, K.S. and Carson, N. and Jeyaratnam, J. and McWilliams, S. and Spruyt, K. and Van der Loos, H.F.M. and Kuo, C. and Ipsiroglu, O.
DOI: 10.1016/j.dib.2021.106770
2021Iron deficiency and sleep – A scoping review
Sleep Medicine Reviews
Leung, W. and Singh, I. and McWilliams, S. and Stockler, S. and Ipsiroglu, O.S.
DOI: 10.1016/j.smrv.2020.101274
2020Barriers and facilitators to treating insomnia in children with autism spectrum disorder and other neurodevelopmental disorders: Parent and health care professional perspectives
Research in Developmental Disabilities
Tan-MacNeill, K.M. and Smith, I.M. and Jemcov, A. and Keeler, L. and Chorney, J. and Johnson, S. and Weiss, S.K. and Begum, E.A. and Brown, C.A. and Constantin, E. and Godbout, R. and Hanlon-Dearman, A. and Ipsiroglu, O. and Reid, G.J. and Shea, S. and Corkum, P.V.
DOI: 10.1016/j.ridd.2020.103792
2020An eHealth insomnia intervention for children with neurodevelopmental disorders: Results of a usability study
Research in Developmental Disabilities
Tan-MacNeill, K.M. and Smith, I.M. and Weiss, S.K. and Johnson, S.A. and Chorney, J. and Constantin, E. and Shea, S. and Hanlon-Dearman, A. and Brown, C.A. and Godbout, R. and Ipsiroglu, O. and Reid, G.J. and Corkum, P.V.
DOI: 10.1016/j.ridd.2020.103573
2020Is Fidgety Philip's ground truth also ours? The creation and application of a machine learning algorithm
Journal of Psychiatric Research
Beyzaei, N. and Bao, S. and Bu, Y. and Hung, L. and Hussaina, H. and Maher, K.S. and Chan, M. and Garn, H. and Kloesch, G. and Kohn, B. and Kuzeljevic, B. and McWilliams, S. and Spruyt, K. and Tse, E. and Machiel Van der Loos, H.F. and Kuo, C. and Ipsiroglu, O.S.
DOI: 10.1016/j.jpsychires.2020.08.033
2020Treatment algorithm for the use of psychopharmacological agents in individuals prenatally exposed to alcohol and/or with diagnosis of fetal alcohol spectrum disorder (Fasd)
Journal of Population Therapeutics and Clinical Pharmacology
Mela, M. and Hanlon-Dearman, A. and Ahmed, A.G. and Rich, S.D. and Densmore, R. and Reid, D. and Barr, A.M. and Osser, D. and Anderson, T. and Suberu, B. and Ipsiroglu, O. and Rajani, H. and Loock, C.
DOI: 10.15586/jptcp.v27i3.681
2020Assessment and treatment of pediatric behavioral sleep disorders in Canada
Sleep Medicine
Corkum, P. and Weiss, S. and Hall, W. and Brown, C. and Chambers, C. and Constantin, E. and Godbout, R. and Hanlon-Dearman, A. and Ipsiroglu, O. and Reid, G.J. and Shea, S. and Smith, I.M. and Stremler, R. and Witmans, M.
DOI: 10.1016/j.sleep.2018.11.007
2019Prenatal alcohol exposure and sleep-wake behaviors: exploratory and naturalistic observations in the clinical setting and in an animal model
Sleep Medicine
Ipsiroglu, O.S. and Wind, K. and Hung, Y.-H.A. and Berger, M. and Chan, F. and Yu, W. and Stockler, S. and Weinberg, J.
DOI: 10.1016/j.sleep.2018.10.006
2019Nervensystem
Pädiatrie
E. Boltshauser and A. M. Kaindl and O. Ipsiroglu and I. Krägeloh-Mann and K. Rostásy and M. Schöning and S. Stöckler-Ipsiroglu and J. Krauß and T. Schweitzer
DOI: 10.1007/978-3-662-57295-5_8
2019Challenging sleep-wake behaviors reported in informal, conversational interviews of caregivers of children with fetal alcohol spectrum disorder
International Journal of Developmental Disabilities
Spruyt, K. and Ipsiroglu, O. and Stockler, S. and Reynolds, J.N.
DOI: 10.1080/20473869.2016.1229395
2018Sleep–wake–behaviour app towards developing a database for informing e-coaching solutions for neurodevelopmental disorders in children
PervasiveHealth: Pervasive Computing Technologies for Healthcare
Heng, T.B. and Gupta, A. and Shaw, C. and Raber, C. and Schilling, M. and Chen, N. and Peng, D. and Zhao, B. and Ipsiroglu, O. and Berger, M. and Beyzaei, N.
DOI: 10.1145/3240925.3240976
2018Optimizing an eHealth insomnia intervention for children with neurodevelopmental disorders: a Delphi study
Sleep Health
Ali, N. and Rigney, G. and Weiss, S.K. and Brown, C.A. and Constantin, E. and Godbout, R. and Hanlon-Dearman, A. and Ipsiroglu, O. and Reid, G.J. and Shea, S. and Smith, I.M. and Van der Loos, M. and Corkum, P.V.
DOI: 10.1016/j.sleh.2017.12.008
2018A systematic review to explore the feasibility of a behavioural sleep intervention for insomnia in children with neurodevelopmental disorders: A transdiagnostic approach
Sleep Medicine Reviews
Rigney, G. and Ali, N.S. and Corkum, P.V. and Brown, C.A. and Constantin, E. and Godbout, R. and Hanlon-Dearman, A. and Ipsiroglu, O. and Reid, G.J. and Shea, S. and Smith, I.M. and Van der Loos, H.F.M. and Weiss, S.K.
DOI: 10.1016/j.smrv.2018.03.008
2018Detection of periodic leg movements in sleep: A comparison of electromyography and 3D video analysis,Detektion periodischer Beinbewegungen im Schlaf: Ein Vergleich von Elektromyographie und 3D-Videoanalyse
Somnologie
Garn, H. and Castrucci, M. and Kohn, B. and Wiesmeyr, C. and Dittrich, K. and Kloesch, G. and Stepansky, R. and Wimmer, M. and Stefanic, A. and B{\"o}ck, M. and Mandl, M. and Ipsiroglu, O. and Grossegger, D. and Kemethofer, M. and Seidel, S.
DOI: 10.1007/s11818-017-0117-5
2017"Emplotted Narratives" and Structured "Behavioral Observations" Supporting the Diagnosis of Willis-Ekbom Disease/Restless Legs Syndrome in Children with Neurodevelopmental Conditions.
Ipsiroglu OS and Beyzaei N and Berger M and Wagner AL and Dhalla S and Garden J and Stockler S
DOI: 10.1111/cns.12564
PubMed: 27292821
06/20163D detection of periodic limb movements in sleep
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Garn, H. and Kohn, B. and Dittrich, K. and Wiesmeyr, C. and Kloesch, G. and Stepansky, R. and Wimmer, M. and Ipsiroglu, O. and Grossegger, D. and Kemethofer, M. and Seidel, S.
DOI: 10.1109/EMBC.2016.7590731
2016"Diagnosis by behavioral observation" home-videosomnography - a rigorous ethnographic approach to sleep of children with neurodevelopmental conditions.
Ipsiroglu OS and Hung YH and Chan F and Ross ML and Veer D and Soo S and Ho G and Berger M and McAllister G and Garn H and Kloesch G and Barbosa AV and Stockler S and McKellin W and Vatikiotis-Bateson E
DOI: 10.3389/fpsyt.2015.00039
PubMed: 25852578
2015Pathways to Overmedication and Polypharmacy: Case Examples from Adolescents with Fetal Alcohol Spectrum Disorders
The Science and Ethics of Antipsychotic Use in Children
DOI: 10.1016/B978-0-12-800016-8.00006-4
2015A randomized controlled trial of an intervention for infants' behavioral sleep problems.
Hall WA and Hutton E and Brant RF and Collet JP and Gregg K and Saunders R and Ipsiroglu O and Gafni A and Triolet K and Tse L and Bhagat R and Wooldridge J
DOI: 10.1186/s12887-015-0492-7
PubMed: 26567090
2015Rising antipsychotic prescriptions for children and youth: cross-sectoral solutions for a multimodal problem.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
Di Pietro N and Illes J and Canadian Working Group on Antipsychotic Medications and Children
DOI: 10.1503/cmaj.131604
PubMed: 24664655
03/2014"They silently live in terror…" why sleep problems and night-time related quality-of-life are missed in children with a fetal alcohol spectrum disorder.
Ipsiroglu OS and McKellin WH and Carey N and Loock C
DOI: 10.1016/j.socscimed.2012.10.027
PubMed: 23305724
02/2013Cultural aspects in the management of inborn errors of metabolism.
Stockler S and Moeslinger D and Herle M and Wimmer B and Ipsiroglu OS
DOI: 10.1007/s10545-012-9455-4
PubMed: 22358739
11/2012Neurophysiology of circadian rhythm sleep disorders of children with neurodevelopmental disabilities.
Jan JE and Bax MC and Owens JA and Ipsiroglu OS and Wasdell MB
DOI: 10.1016/j.ejpn.2012.01.002
PubMed: 22264650
09/2012Sleep Health Issues for Children with FASD: Clinical Considerations.
Jan JE and Asante KO and Conry JL and Fast DK and Bax MC and Ipsiroglu OS and Bredberg E and Loock CA and Wasdell MB
DOI: 10.1155/2010/639048
PubMed: 20706655
2010Outcome after renal transplantation in children from native and immigrant families in Austria
European Journal of Pediatrics
Oztek, F.Z. and Ipsiroglu, O. and Mueller, T. and Aufricht, C.
DOI: 10.1007/s00431-008-0698-x
2009Sleep hygiene for children with neurodevelopmental disabilities.
Jan JE and Owens JA and Weiss MD and Johnson KP and Wasdell MB and Freeman RD and Ipsiroglu OS
DOI: 10.1542/peds.2007-3308
PubMed: 19047255
12/2008How to approach pediatric sleep medicine in British Columbia: A consensus paper
British Columbia Medical Journal
2008Wolf-Hirschhorn syndrome and infantile epileptic encephalopathy. Case report and literature review,Wolf-Hirschhorn-syndrom und frühkindliche epilepsie. Fallbericht und literaturübersicht
Monatsschrift fur Kinderheilkunde
Mercimek-Mahmutoglu, S. and Ipsiroglu, O.S. and Feucht, M. and Buchta-Scheicher, B. and Haas, O. and Prayer, D. and St{\"o}ckler-Ipsiroglu, S.
DOI: 10.1007/s00112-006-1377-5
2007Sudden infant death syndrome in Austria: Guidelines on diagnosis, data capture and prevention,Plötzlicher säuglingstod in Österreich: Richtlinien zur diagnostik, datenerfassung und prävention
Monatsschrift fur Kinderheilkunde
Kenzian, H. and Kerbl, R. and Burger, J. and F{\"o}rster, H. and H{\"a}chl, G. and Ipsiroglu, O. and Kiechl-Kohlendorfer, U. and Kurz, H. and Kurz, R. and M{\"u}ller, G. and Pfurtscheller, K. and Pupp-Peglow, U. and Rath-Wacenovsky, R. and Sauseng, W. and Schabel, F. and Seimann, R. and Simma, B. and Sperl, W. and Zieglauer, H. and Zotter, H.
DOI: 10.1007/s00112-007-1493-x
2007Morning and daytime fatigue in school children - Does school start too early? Data and thoughts on a later start to school,Morgen- und tagesmüdigkeit bei schulkindern - Beginnt die schule zu früh? Daten und gedanken zu einem späteren schulbeginn
Monatsschrift fur Kinderheilkunde
Kerbl, R. and Zotter, H. and Sauseng, W. and Kenzian, H. and Ipsiroglu, O.
DOI: 10.1007/s00112-006-1437-x
2006Transcultural pediatrics: compliance and outcome of phenylketonuria patients from families with an immigration background.
Ipsiroglu OS and Herle M and Spoula E and Möslinger D and Wimmer B and Burgard P and Bode H and Stöckler-Ipsiroglu S
DOI: 10.1007/s00508-005-0327-x
PubMed: 16158204
08/2005The migration challenge: Everyday practice in pediatrics - Introduction to the topic,Herausforderung migration: Der alltag in der pädiatrie
Monatsschrift fur Kinderheilkunde
Ipsiroglu, O.S. and Kurz, R.
DOI: 10.1007/s00112-005-1080-y
2005Vanishing white matter disease. A new leukoencephalopathy,Vanishing-White-Matter-Erkrankung. Eine neue Leukoenzephalopathie
Padiatrische Praxis
Mercimek-Mahmutoglu, S. and van der Knaap, M. and Ipsiroglu, O. and Paky, F. and Prayer, D. and Konstantopoulou, D. and St{\"o}ckler-Ipsiroglu, S.
2005Transcultural paediatrics. An introduction,Transkulturelle pädiatrie. Eine einführung
Monatsschrift fur Kinderheilkunde
Ipsiroglu, O.S. and Bode, H.
DOI: 10.1007/s00112-004-1069-y
2005Effects of open vs. closed system endotracheal suctioning on cerebral blood flow velocities in mechanically ventilated extremely low birth weight infants.
Rieger H and Kuhle S and Ipsiroglu OS and Heinzl H and Popow CN
DOI: 10.1515/jpm.2005.077
PubMed: 16238539
2005Inborn metabolic diseases. Special aspects of the care of children from immigrant families,Angeborene stoffwechselerkrankungen. Besonderheiten in der betreuung von kindern aus migrantenfamilien
Monatsschrift fur Kinderheilkunde
St{\"o}ckler-Ipsiroglu, S. and Herle, M. and Nennstiel, U. and Wendel, U. and Burgard, P. and Plecko, B. and Ipsiroglu, O.S.
DOI: 10.1007/s00112-004-1072-3
2005A novel technique to measure position-dependent resistance changes in the vertebral arteries postmortem: new insights into the aetiology of SIDS?
Wald M and Klupp N and Lawrenz K and Puig S and Heimberger K and Reiter C and Pollak A and Ipsiroglu O
DOI: 10.1080/08035250410027652
PubMed: 15384878
09/2004Risk factors and natural history of habitual snoring.
Urschitz MS and Guenther A and Eitner S and Urschitz-Duprat PM and Schlaud M and Ipsiroglu OS and Poets CF
DOI: 10.1378/chest.126.3.790
PubMed: 15364758
09/2004[Snoring as an sign of sleep disorders in 11- to 15-year-old school children--initial results of a Vienna epidemiologic study].
Török K and Fatemi A and Werner I and Kerbl R and Schwarz B and Ipsiroglu OS
DOI: 10.1007/bf03040406
PubMed: 14768531
12/2003Classification of sudden infant death (SID) cases in a multidisciplinary setting. Ten years experience in Styria (Austria).
Kerbl R and Zotter H and Einspieler C and Roll P and Ratschek M and Köstl G and Strenger V and Hoffmann E and Perrogon A and Zötsch W and Schober P and Gränz A and Sauseng W and Bachler I and Kenner T and Ipsiroglu O and Kurz R and Styrian Sudden Infant Death Study Group
DOI: 10.1007/bf03040411
PubMed: 14768536
12/2003[Sudden infant death and pediatric sleep medicine].
Förster H and Ipsiroglu O and Kerbl R and Paditz E
DOI: 10.1007/bf03040402
PubMed: 14768527
12/2003Alterations in advice and prevention of SIDS established at the 4th Austrian SIDS Consensus Meeting in 1998,Änderungen in der SIDS-beratung und -prävention im anschluss an den 4. Österreichischen SIDS-konsens von 1998
Monatsschrift fur Kinderheilkunde
Ipsiroglu, O.S. and Urschitz, M. and Pollak, A.
DOI: 10.1007/s00112-002-0593-x
2003Self-reported organic and nonorganic sleep problems in schoolchildren aged 11 to 15 years in Vienna.
Ipsiroglu OS and Fatemi A and Werner I and Paditz E and Schwarz B
DOI: 10.1016/s1054-139x(02)00423-8
PubMed: 12401431
11/2002[Sudden infant death in Austria--status quo and recommendations of the SIDS Consensus Working Group for Improved Registration].
Ipsiroglu OS and Fatemi A and Rabl W and Klupp N and Roll P and Meyer H and Kerbl R and Kurz R
PubMed: 12416287
09/2002Oral beta-hydroxybutyrate supplementation in two patients with hyperinsulinemic hypoglycemia: monitoring of beta-hydroxybutyrate levels in blood and cerebrospinal fluid, and in the brain by in vivo magnetic resonance spectroscopy.
Pediatric research
Plecko B and Stoeckler-Ipsiroglu S and Schober E and Harrer G and Mlynarik V and Gruber S and Moser E and Moeslinger D and Silgoner H and Ipsiroglu O
DOI: 10.1203/00006450-200208000-00025
PubMed: 12149510
08/2002Sudden infant death: no evidence for linkage to common polymorphisms in the uncoupling protein-1 and the beta3-adrenergic receptor genes.
Fatemi A and Item C and Stöckler-Ipsiroglu S and Ipsiroglu O and Sperl W and Patsch W and Strobl W
DOI: 10.1007/s00431-002-0940-x
PubMed: 12029453
06/2002Effects of oral creatine supplementation in a patient with MELAS phenotype and associated nephropathy.
Barisic N and Bernert G and Ipsiroglu O and Stromberger C and Müller T and Gruber S and Prayer D and Moser E and Bittner RE and Stöckler-Ipsiroglu S
DOI: 10.1055/s-2002-33679
PubMed: 12200746
06/2002Oral ß-hydroxybutyrate supplementation in two patients with hyperinsulinemic hypoglycemia: Monitoring of ß-hydroxybutyrate levels in blood and cerebrospinal fluid, and in the brain by In vivo magnetic resonance spectroscopy
Pediatric Research
Plecko, B. and Stoeckler-Ipsiroglu, S. and Schober, E. and Harrer, G. and Mlynarik, V. and Gruber, S. and Moser, E. and Moeslinger, D. and Silgoner, H. and Ipsiroglu, O.
DOI: 10.1203/01.PDR.0000019439.27135.2B
2002Sudden infant death in Austria - Status quo and position statement for registration of the Austrian SIDS Consensus Group,Der plötzliche säuglingstod in Österreich - Status quo und empfehlungen der SIDS-konsensusarbeitsgruppe zur verbesserten erfassung
Wiener Klinische Wochenschrift
Ipsiroglu, O.S. and Fatemi, A. and Rabl, W. and Klupp, N. and Roll, P. and Meyer, H. and Kerbl, R. and Kurz, R.
2002Heart rate variability in the paediatric sleep laboratory - Recommendations for measurement and analysis,Empfehlungen für die bestimmung der herzfrequenzvariabilität im pädiatrischen schlaflabor
Somnologie
Patzak, A. and Mrowka, R. and Springer, S. and Eckardt, T. and Ipsiroglu, O.S. and Erler, T. and Hofmann, S. and Gramse, V.
DOI: 10.1046/j.1439-054x.2002.02002.x
2002Position dependent changes of cerebral blood flow velocities in premature infants.
Eichler F and Ipsiroglu O and Arif T and Popow C and Heinzl H and Urschitz M and Pollak A
DOI: 10.1007/s004310100806
PubMed: 11686511
10/2001Can hypocapnia reduce cerebral embolization during cardiopulmonary bypass?
Plöchl W and Krenn CG and Cook DJ and Gollob E and Pezawas T and Schima H and Ipsiroglu O and Wollenek G and Grubhofer G
DOI: 10.1016/s0003-4975(01)02826-0
PubMed: 11565668
09/2001[Communication barriers in the management of immigrants and their children. An analysis and possible solutions based on case reports]
Wimmer B and Ipsiroglu OS
PubMed: 11571841
08/2001Changes of tissue creatine concentrations upon oral supplementation of creatine-monohydrate in various animal species.
Ipsiroglu OS and Stromberger C and Ilas J and Höger H and Mühl A and Stöckler-Ipsiroglu S
DOI: 10.1016/s0024-3205(01)01268-1
PubMed: 11665842
08/2001[Prevalence of sleep disorders in school children between 11 and 15 years of age]
Ipsiroglu OS and Fatemi A and Werner I and Tiefenthaler M and Urschitz MS and Schwarz B
PubMed: 11383383
04/2001[Sleep medicine between science and clinical practice--how long can we avoid the issue?]
Ipsiroglu OS and Saletu B
PubMed: 11383379
04/2001Prevalence of sleep disorders in school children between 11 and 15 years,Häufigkeit von schlafstörungen bei schulkindern zwischen 11 und 15 jahren
Wiener Klinische Wochenschrift
Ipsiroglu, O.S. and Fatemi, A. and Werner, I. and Tiefenthaler, M. and Urschitz, M.S. and Schwarz, B.
2001Communication barrries in health care of migrants and their children. Exemplary cases, analysis and suggestions for improvement,Kommunikationsbarrieren in der betreuung von migrantinnen und deren kindern analyse und lösungsvorschläge anhand von fallbeispielen
Wiener Klinische Wochenschrift
Wimmer, B. and Ipsiroglu, O.S.
2001Can hypocapnia reduce cerebaral embolization during cardiopulmonary bypass: Invited commentary
Annals of Thoracic Surgery
Pl{\"o}chl, W. and Krenn, C.G. and Cook, D.J. and Gollob, E. and Pezawas, T. and Schima, H. and Ipsiroglu, O. and Wollenek, G. and Grubhofer, G.
DOI: 10.1016/S0003-4975(01)03021-1
2001Editorial,Schlafmedizin zwischen wissenschaft und alltag - Wie lange dürfen wir wegschauen?
Wiener Klinische Wochenschrift
Ipsiroglu, O.S. and Saletu, B.
2001Being a child and having children,Kindsein und kinderhaben an der zeitenwende
Monatsschrift fur Kinderheilkunde
Ipsiroglu, O. and St{\"o}ckler-Ipsiroglu, S. and Plecko, B. and Arbeiter, K. and Dunitz-Scheer, M. and Heitger, A. and Huber, W.-D. and J{\"u}rgenssen, O.A. and Kaltenbrunner, K. and Koller, D. and Maurer, W. and M{\"u}ller, T. and Paky, F. and Pollak, A. and Salzer, H. and Skladal, D. and Stromberger, C. and Trop, M. and F{\"o}rster-Wald, E. and Weikmann, E. and Aksu, F. and Thyen, U. and Hanefeld, F. and Auerswald, G. and Christen, H.-J. and Faust, J. and Gabriel, R. and Genzel, O. and Haas, D. and Hasselmann, O. and Heinen, F. and Karch, D. and Kirschstein, M. and Kluger, G. and Korn-Merker, E. and Kr{\"a}geloh-Mann, I. and Marg, W. and Mayatepek, E. and Meil{\ss}ner, T. and Niemann, G. and P{\"u}st, B. and Schmitt, B. and Schoening, M. and Schulze, A. and Sperner, J. and Tegtmeyer, F.K. and Weissert, M. and Wiebicke, W. and Wilken, B. and Zschocke, J. and Bentele, K. and Schinzel, A. and Stral{\ss}burg, M. and Jurgenssen, O.A. and T{\"o}nz, O. and Bl{\"a}ker, F.
DOI: 10.1007/s001120170149
2001[Orthostasis in halothane anesthesia. A model situation for studying cerebrovascular autoregulation in infants]
Ipsiroglu OS and Köhler J and Meger B and Pumberger W and Grabner C and Semsroth M
DOI: 10.1007/s001010070091
PubMed: 10928253
06/2000[4th Austrian SIDS Consensus-Consultation and the Viennese SIDS prevention campaign "Secure Sleep"]
Ipsiroglu OS and Kerbl R and Urschitz M and Kurz R
PubMed: 10763529
03/2000[Secure Sleep--SIDS prevention campaign by children's hospitals of Vienna]
Ipsiroglu OS and Lischka A and Sacher M and Stögmann W and Pollak A
PubMed: 10763528
03/2000[Evaluation of the cardiorespiratory monitor SpiroGuard C for infants. Improved registration of respiratory events by new sensors and intelligent alarm management system]
Urschitz MS and Eichler F and Popow C and Ipsiroglu OS
PubMed: 10763536
03/2000[Viennese SIDS prevention campaign-- a quality management project]
Ipsiroglu OS and Stekel H and Pollak A and Kaspar L
PubMed: 10763535
03/2000Estimating percentage total body fat and determining subcutaneous adipose tissue distribution with a new noninvasive optical device LIPOMETER.
Möller R and Tafeit E and Smolle KH and Pieber TR and Ipsiroglu O and Duesse M and Huemer C and Sudi K and Reibnegger G
DOI: 10.1002/(sici)1520-6300(200003/04)12:23.0.co;2-2
PubMed: 11534019
03/2000[Viennese SIDS prevention campaign-- a quality management project].
Wiener klinische Wochenschrift
Osman Ipsiroglu and Stekel H and Pollak A and Kaspar L
PubMed: 10763535
03/2000[Heart rate variability--physiology, methods of registration and application in pediatric sleep laboratory]
Patzak A and Mrowka R and Springer S and Eckard T and Ipsiroglu OS and Erler T and Hofmann S
PubMed: 10763537
03/2000[Diagnostic imaging in neonatal stroke].
Kuhle S and Ipsiroglu O and Puig S and Weninger M and Prayer D
DOI: 10.1007/s001170050005
PubMed: 10663160
01/2000Evaluation of the cardiorespiratory monitor SpiroGuard C for infants,Evaluierung des herz-atem-uberwachungsgerates SpiroGuard C fur sauglinge: Verbesserte erfassung von respiratorischen ereignissen durch neue sensorik und intelligentes alarmmanagement?
Wiener Klinische Wochenschrift
Urschitz, M.S. and Eichler, F. and Popow, C. and Ipsiroglu, O.S.
2000Safe sleeping - The sudden infant death syndrome (SIDS) prevention campaign of the Vienna children hospitals,Sicheres schlafen - Die SIDS-praventionskampagne der wiener kinderspitaler
Wiener Klinische Wochenschrift
Ipsiroglu, O.S. and Lischka, A. and Sacher, M. and Stogmann, W. and Pollak, A.
2000Heart rate variability - Physiology, methods of registration and application in the pediatric sleep laboratory,Herzfrequenzvariabilitat - Methoden, physiologie und applikation im padiatrischen schlaflabor
Wiener Klinische Wochenschrift
Patzak, A. and Mrowka, R. and Springer, S. and Eckard, T. and Ipsiroglu, O.S. and Erler, T. and Hofmann, S.
20004th Austrian SIDS-consensus meeting and Vienna SIDS prevention campaign 'Safe Sleep',4. Osterreichisches SIDS-konsensus-gesprach anlasslich der Wiener SIDS- praventionskampagne 'Sicheres Schlafen'
Wiener Klinische Wochenschrift
2000Vienna SIDS prevention campaign - A quality management project,Die Wiener SIDS-praventionskampagne als qualitatsmanagementprojekt
Wiener Klinische Wochenschrift
Ipsiroglu, O.S. and Stekel, H. and Pollak, A. and Kaspar, L.
2000SIDS related anxiety - A risk factor analysis
Wiener Klinische Wochenschrift
Leitich, H. and Tiefenthaler, M. and Popow, C. and Seyfried-Holzer, G. and Urschitz, M. and Ipsiroglu, O.S. and Pollak, A.
2000Estimating percentage total body fat and determining subcutaneous adipose tissue distribution with a new noninvasive optical device LIPOMETER
American Journal of Human Biology
2000Systemic blood pressure and cerebral blood flow velocity during carotid surgery.
Grubhofer G and Lassnigg A and Pernerstorfer T and Ipsiroglu O and Czerny M and Polterauer P and Hiesmayr M
PubMed: 10670796
12/1999Cerebral Doppler sonography of the neonate. A resume after 20 years and future aspects.
Ipsiroglu OS and Eichler F and Stoeckler-Ipsiroglu S
PubMed: 10572729
12/1999Cerebral blood flow velocities in an infant with moyamoya disease.
Ipsiroglu OS and Eichler F and Stöckler-Ipsiroglu S and Trattnig S
DOI: 10.1016/s0887-8994(99)00070-3
PubMed: 10580888
10/1999Systemic blood pressure and cerebral blood flow velocity during carotid surgery
Thoracic and Cardiovascular Surgeon
Grubhofer, G. and Lassnigg, A. and Pernerstorfer, T. and Ipsiroglu, O. and Czerny, M. and Polterauer, P. and Hiesmayr, M.
DOI: 10.1055/s-2007-1013178
1999Cerebral Doppler sonography of the neonate: A resume after 20 years and future aspects
Clinics in Perinatology
Ipsiroglu, O.S. and Eichler, F. and Stoeckler-Ipsiroglu, S.
DOI: 10.1016/s0095-5108(18)30027-7
1999Effect of open versus closed system suctioning on cerebral blood flow velocities in mechanically ventilated newborn infants
Pediatric Research
Rieger, H. and Ipsiroglu, O. and Popow, C.
DOI: 10.1203/00006450-199809000-00192
1998Are adult transcranial Doppler systems suitable for application in neonates?
Ipsiroglu OS and Steck J and Michel E and Pessenhofer H and Jorch G and Pollak A
DOI: 10.1007/bf02282884
PubMed: 8911894
11/1996Gewebeerwärmung beim Langzeitmonitoring der Zerebralen Blutflußgeschwindigkeiten Mittels Dopplersonographie
Biomedizinische Technik
Froese, N. and Ipsiroglu, O.S. and Schlegel, J.C. and Pollak, A. and Steck, J. and Schmitt, R.M. and Pessenhofer, H.
DOI: 10.1515/bmte.1995.40.s2.184
1995Langzeitmonitoring der zerebralen Hämodynamik mittels transkranieller Dopplersonographie bei Hochrisikoneugeborenen
Biomedizinische Technik
Schlegel, J.C. and Ipsiroglu, O.S. and Froese, N. and Pollak, A. and Pessenhofer, H. and Klein, T. and Steck, J. and Schmitt, R.M.
DOI: 10.1515/bmte.1995.40.s2.45
1995Biomedizintechnische Beratung: Notwendigkeit oder Luxus?
Biomedizinische Technik
Ipsiroglu, O.S. and Pollak, A. and Pessenhofer, H.
DOI: 10.1515/bmte.1995.40.s2.30
1995Cerebral blood flow velocities in the first minutes of life.
Ipsiroglu OS and Stöckler S and Häusler MC and Kainer F and Rosegger H and Weiss PA and Winter R
DOI: 10.1007/bf01956162
PubMed: 8444260
03/1993Ein fall schwerer peripartaler asphyxie
Gynakologisch-geburtshilfliche Rundschau
Ipsiroglu, O.S. and Hofmann, H.M.H. and Weiss, P.A.M.
1993Perinatal management of surgical malformations: Evaluation study NrII/C of the Styrian malformation register,PERINATOLOGISCHES MANAGEMENT VON SOFORT OPERATIONSPFLICHTIGEN FEHLBILDUNGEN - EVALUIERUNGSSTUDIE NR II/C DES STEIRISCHES FEHLBILDUNGSREGISTERS
Archives of Gynecology and Obstetrics
1991Dys-tocolysis: modified vaginal delivery of premature infants?,dysTOKOLYSE: modifizierte vaginale Entbindung von Frühgeborenen?
Gynäkologische Rundschau
Ipsiroglu, O.S. and Rosegger, H. and Weiss, P.A.
1990The value of umbilical cord blood cortisol,Stellenwert von Nabelschnur-(NS) Cortisol.
Gynäkologische Rundschau
Ipsiroglu, O.S. and Semmelrock, J. and Gmoser, G. and St{\"o}ckler, S. and Rosegger, H.
1990[Dys-tocolysis: modified vaginal delivery of premature infants?]
Ipsiroglu OS and Rosegger H and Weiss PA
PubMed: 2079278
1990[The value of umbilical cord blood cortisol]
Ipsiroglu OS and Semmelrock J and Gmoser G and Stöckler S and Rosegger H
PubMed: 2079268
1990[Pregnancy and neonatal screening in Austria]
Stöckler S and Ipsiroglu OS and Häusler M
PubMed: 2678759
09/1989[The value of prenatal ultrasound screening exemplified by abnormalities of the urogenital system. Data from the Styrian malformation register 1985 to 1987]
Häusler M and Hofmann HM and Schaffer M and Hofer P and Rollett H and Ring E and Ipsiroglu OS
PubMed: 2660419
05/1989[Steiermark data of congenital abnormalities with regional classification and comparative international values]
Häusler M and Hofmann HM and Hofer P and Schaffer M and Ipsiroglu O
PubMed: 2613025
1989The value of prenatal ultrasound screening as exemplified by urinary tract malformations. Data of the Styrian Malformation Register 1985 to 1987,DER WERT DES PRANATALEN ULTRASCHALL-SCREENINGS AM BEISPIEL VON FEHLBILDUNGEN DES UROGENITALSYSTEMS. DATEN AUS DEM STEIRISCHEN FEHLBILDUNGSREGISTER 1985 BIS 1987
Wiener Klinische Wochenschrift
Hausler, M. and Hofmann, H.M.H. and Schaffer, M. and Hofer, P. and Rollett, H. and Ring, E. and Ipsiroglu, O.S.
1989Steirische erhebung angeborener fehlbiidungen mit regionaler zuordnung und internationalen vergleichswerten
Gynakologisch-geburtshilfliche Rundschau
H{\"a}usler, M. and Hofmann, H.M.H. and Hofer, P. and Schaffer, M. and Ipsiroglu, O.
DOI: 10.1159/000271070
1989[Congenital metabolic diseases as a cause of acute illnesses in the neonatal period]
Stöckler S and Ipsiroglu OS and Paschke E
PubMed: 2677512
1989Ultrasound screening in pregnancy and neonatal mass screening for inherited metabolic disorders in Austria,SCHWANGEREN- UND NEUGEBORENENSCREENING IN OSTERREICH
Wiener Klinische Wochenschrift
Stockler, S. and Ipsiroglu, O.S. and Hausler, M.
1989Inborn errors of metabolism as a cause of acute illness in the neonate,ANGEBORENE STOFFWECHSELERKRANKUNGEN ALS URSACHE AKUTER KRANKHEITSBILDER IN DER NEUGEBORENENPERIODE
Klinische Padiatrie
Stockler, S. and Ipsiroglu, O.S. and Paschke, E.
DOI: 10.1055/s-2008-1026729
1989Management beim vorzeitigen blasensprung
Gynakologisch-geburtshilfliche Rundschau
Ralph, G. and Lichtenegger, W. and Kopera, D. and Ipsiroglu, O.
DOI: 10.1159/000270488
1987 - Research
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NeuroDevNet "Better Days/Better Nights"
SWAPPs 4KIDS with NDDs. Structured functional Sleep/Wake Behaviour assessment in children with neurodevelopmental disabilities/disorders & monitoring therapeutic interventions.
Overview: Our team has developed a web app (sleep/wake behaviours App, SWAPP) to facilitate recognition, characterization and monitoring of sleep problems (SPs) and daytime sequelae in children and youth with neurodevelopmental disabilities (NDDs) [http://youtu.be/60Kx4jmU6Is]. The use of the SWAPP in clinical practice has created evidence for revisiting clinical practice guidelines and improving existing policies by highlighting the fundamental need, to recognize and appropriately treat sleep problems in most vulnerable populations. We collaborate with a network of multidisciplinary stakeholders, including non-governmental organizations (representing patients) and recently with decision makers to ensure rapid and sustainable implementation and policy change.
Objectives of our research: Further development of the SWAPP and associated database. We are particularly interested in medication strategies, captured by the medication module for monitoring psychotropic drug prescriptions and behavioural / neurologic adverse drug reactions. A free downloadable smart-phone version of our SWAPP for caregivers and practitioners to (self-)assess / recognize the concept of challenging sleep / wake behaviours will be ready around fall 2015.
Significance: At the end of the project we will have a series of validated and commercially available SWAPPs with patient driven self-assessment modules for participatory data collection on poorly understood challenging-disruptive sleep/wake behaviours. Patient and community tier input during all stages of development will result in effective implementation of the SWAPPs through knowledge translation activities in collaboration with non-governmental organizations.HMovements Automated Movement Detection Algorithm
The HMovements automated movement detection algorithm assists clinicians with analyzing the body movements of patients with ADHD, restless legs syndrome/Willis Ekbom disease, and/or agitation syndrome (akathisia) during standardized sitting videos. To learn more and download the open source algorithm, click here: https://doi.org/10.17632/ytst4kss9p.4Grants2013/2014 - Peter Wall Institute for Advanced Studies - Visiting Scholar Funding for Dr. Karen Spruyt, Vrije Universiteit, Brussels (together with Dr. Sylvia Stockler).
2012 - Peter Wall Institute for Advanced Studies - Phenotyping Sleep Behaviours Lessons from the Past, Directions for the Future (together with Dr. Bruce Carleton)
2009-2012 - Canadian Institutes of Health Research - Night waking reduction in Canadian infants: A randomized clinical trial of a parent based cognitive and behavioural intervention in community health units. (Co-PI, PI: Dr. Wendy Hall)
Honours & Awards2011
Excellence in Education Award, Learning & Development BC Children's hospital & BC Women's Hospital & Health Care
2008
Transcultural Paediatrics Award, German Society for Socialpaediatrics & Adolescent Medicine and Austrian Society of Paediatrics
Research Group MembersNadia Beyzaei, Senior Research Assistant
Kristina Calli, ASPIRE/iTARGET Project Manager
Olivia Hill, Medical Student
Scout McWilliams, Volunteer
Julian Mollin, Ipsiroglu Postdoctoral
Mark Parinas, INSPIRE Student Volunteer
Natasha Patel, INSPIRE Student, Clinical Coordinator and Research Assistant
Torin Halvorson and Hebah Hussaina awarded Vanier scholarships for immunotherapy and mental health research
BC Children’s Hospital Research Institute (BCCHR) is proud to announce that two of its outstanding research trainees, Torin Halvorson, an MD/PhD student working with the Levings research team, and Hebah Hussaina, a graduate research assistant in the Brussoni Lab, have been awarded the prestigious 2024 Vanier Canada Graduate Scholarship.
