Overview

Kidney disease is an important cause of mortality and morbidity in children as well as adults. Immune-mediated kidney diseases are a major cause of childhood-onset kidney failure, requiring dialysis and kidney transplantation. The kidney is a complex organ with many different cell types and many different functions. The kidney is comprised of hundreds of thousands of nephrons which filter blood and generate urine. Specialized blood vessels called glomeruli form the filtration barrier, and tubules lined with many types of specialized epithelial cells process the filtrate, before it becomes urine. Immune cells and humoral factors such as immunoglobulins and complement components can become dysregulated in the kidney and lead to kidney dysfunction. Treating immune-mediated kidney diseases requires in depth understanding of immunology as well as nephrology.

Publications

Defining renal remission in an international cohort of 248 children and adolescents with lupus nephritis
Rheumatology
Chiara De Mutiis and Scott E Wenderfer and Alvaro Orjuela and Arvind Bagga and Biswanath Basu and Tanmoy Sar and Amita Aggarwal and Avinash Jain and Hui-Kim Yap and Shuichi Ito and Ai Ohnishi and Naomi Iwata and Ozgur Kasapcopur and Audrey Laurent and Antonio Mastrangelo and Masao Ogura and Yuko Shima and Pornpimol Rianthavorn and Clovis A Silva and Vitor Trindade and Ada Dormi and Kjell Tullus
DOI: 10.1093/rheumatology/keab746
05/2022

Lupus Nephritis, Autoantibody Production and Kidney Outcomes in Males with Childhood-Onset Systemic Lupus Erythematosus
Pediatric Reports
Scott E. Wenderfer and Alvaro Orjuela and Mir Reza Bekheirnia and Maria Pereira and Eyal Muscal and Michael C. Braun and Marietta De Guzman
DOI: 10.3390/pediatric14020030
05/2022

Using a Multi-Institutional Pediatric Learning Health System to Identify Systemic Lupus Erythematosus and Lupus Nephritis
Clinical Journal of the American Society of Nephrology
Scott E. Wenderfer and Joyce C. Chang and Amy Goodwin Davies and Ingrid Y. Luna and Rebecca Scobell and Cora Sears and Bliss Magella and Mark Mitsnefes and Brian R. Stotter and Vikas R. Dharnidharka and Katherine D. Nowicki and Bradley P. Dixon and Megan Kelton and Joseph T. Flynn and Caroline Gluck and Mahmoud Kallash and William E. Smoyer and Andrea Knight and Sangeeta Sule and Hanieh Razzaghi and L. Charles Bailey and Susan L. Furth and Christopher B. Forrest and Michelle R. Denburg and Meredith A. Atkinson
DOI: 10.2215/CJN.07810621
01/2022

Lupus Nephritis
Pediatric Nephrology
Scott Wenderfer and Sherene Mason and Christine Bernal and Clovis Artur Almeida da Silva
DOI: 10.1007/978-3-642-27843-3_97-1
09/2021

International Consensus For The Dosing Of Corticosteroids In Childhood-Onset Systemic Lupus Erythematosus With Proliferative Lupus Nephritis
Arthritis & Rheumatology
Nathalie E. Chalhoub and Scott E. Wenderfer and Deborah M. Levy and Kelly Rouster-Stevens and Amita Aggarwal and Sonia I Savani and Natasha M Ruth and Thaschawee Arkachaisri and Tingting Qiu and Angela Merritt and Karen Onel and Beatrice Goilav and Raju P Khubchandani and Jianghong Deng and Adriana R Fonseca and Stacy P. Ardoin and Coziana Ciurtin and Ozgur Kasapcopur and Marija Jelusic and Adam M. Huber and Seza Ozen and Marisa S Klein-Gitelman and Simone Appenzeller and André Cavalcanti and Lampros Fotis and Lim Sern Chin and Rodrigo M Silva and Julia Ramírez- Miramontes and Natalie L Rosenwasser and Claudia Saad-Magalhaes and Dieneke Schonenberg-Meinema and Christiaan Scott and Clovis A. Silva and Sandra Enciso and Maria T Terreri and Alfonso-Ragnar Torres-Jimenez and Maria Trachana and Sulaiman M Al-Mayouf and Prasad Devarajan and Bin Huang and Hermine I Brunner
DOI: 10.1002/art.41930
07/2021

Improving data quality in observational research studies: Report of the Cure Glomerulonephropathy (CureGN) network
Contemporary Clinical Trials Communications
Brenda W. Gillespie and Louis-Philippe Laurin and Dawn Zinsser and Richard Lafayette and Maddalena Marasa and Scott E. Wenderfer and Suzanne Vento and Caroline Poulton and Laura Barisoni and Jarcy Zee and Margaret Helmuth and Francesca Lugani and Margret Kamel and Peg Hill-Callahan and Stephen M. Hewitt and Laura H. Mariani and William E. Smoyer and Larry A. Greenbaum and Debbie S. Gipson and Bruce M. Robinson and Ali G. Gharavi and Lisa M. Guay-Woodford and Howard Trachtman
DOI: 10.1016/j.conctc.2021.100749
06/2021

Cross-sectional study of plasma Axl, ferritin, IGFBP4 and sTNFR2 as biomarkers of disease activity in childhood-onset SLE: A study of the Pediatric Nephrology Research Consortium
Lupus
Soliman, S.A. and Haque, A. and Mason, S. and Greenbaum, L.A. and Hicks, M.J. and Mohan, C. and Wenderfer, S.E.
DOI: 10.1177/09612033211016100
2021

Evaluation of the Reproductive Care Provided to Adolescent Patients in Nephrology Clinics: A Pediatric Nephrology Research Consortium Study
Kidney International Reports
Vasylyeva, T.L. and Page-Hefley, S. and Almaani, S. and Ayoub, I. and Batson, A. and Hladunewich, M. and Howard, N. and Fernandez, H.E. and O'Shaughnessy, M. and Reynolds, M.L. and Wadhwani, S. and Zee, J. and Smoyer, W.E. and Wenderfer, S.E. and Twombley, K.E.
DOI: 10.1016/j.ekir.2021.02.007
2021

GWAS defines pathogenic signaling pathways and prioritizes drug targets for IgA nephropathy
medRxiv
Kiryluk, K. and Sanchez-Rodriguez, E. and Zhou, X.-J. and Zanoni, F. and Liu, L. and Mladkova, N. and Khan, A. and Marasa, M. and Zhang, J.Y. and Balderes, O. and Sanna-Cherchi, S. and Bomback, A.S. and Canetta, P.A. and Appel, G.B. and Radhakrishnan, J. and Trimarchi, H. and Sprangers, B. and Cattran, D.C. and Reich, H. and Pei, Y. and Ravani, P. and Galesic, K. and Maixnerova, D. and Tesar, V. and Stengel, B. and Metzger, M. and Canaud, G. and Maillard, N. and Berthoux, F. and Berthelot, L. and Pillebout, E. and Monteiro, R. and Nelson, R. and Wyatt, R. and Smoyer, W. and Mahan, J. and Samhar, A.-A. and Hidalgo, G. and Quiroga, A. and Weng, P. and Sreedharan, R. and Selewski, D. and Davis, K. and Kallash, M. and Vasylyeva, T.L. and Rheault, M. and Chishti, A. and Ranch, D. and Wenderfer, S.E. and Samsonov, D. and Claes, D.J. and Oleh, A. and Goumenos, D. and Stangou, M. and Nagy, J. and Kovacs, T. and Fiaccadori, E. and Amoroso, A. and Barlassina, C. and Cusi, D. and Vecchio, L.D. and Battaglia, G.G. and Bodria, M. and Boer, E. and Bono, L. and Boscutti, G. and Caridi, G. and Lugani, F. and Ghiggeri, G. and Coppo, R. and Peruzzi, L. and Esposito, V. and Esposito, C. and Feriozzi, S. and Polci, R. and Frasca, G. and Galliani, M. and Garozzo, M. and Mitrotti, A. and Gesualdo, L. and Granata, S. and Zaza, G. and Londrino, F. and Magistroni, R. and Pisani, I. and Magnano, A. and Marcantoni, C. and Messa, P. and Mignani, R. and Pani, A. and Ponticelli, C. and Roccatello, D. and Salvadori, M. and Salvi, E. and Santoro, D. and Gembillo, G. and Savoldi, S. and Spotti, D. and Zamboli, P. and Izzi, C. and Alberici, F. and Delbarba, E. and Florczak, M. and Krata, N. and Mucha, K. and P?czek, L. and Niemczyk, S. and Moszczuk, B. and Pa?czyk-Tomaszewska, M. and Mizerska-Wasiak, M. and Perkowska-Ptasi?ska, A. and B?czkowska, T. and Durlik, M. and Pawlaczyk, K. and Sikora, P. and Zaniew, M. and Kaminska, D. and Krajewska, M. and Kuzmiuk-Glembin, I. and Heleniak, Z. and Bullo-Piontecka, B. and Liberek, T. and D?bska-Slizien, A. and Hryszko, T. and Materna-Kiryluk, A. and Miklaszewska, M. and Szczepa?ska, M. and Dyga, K. and Machura, E. and Siniewicz-Luze?czyk, K. and Pawlak-Bratkowska, M. and Tkaczyk, M. and Runowski, D. and Kwella, N. and Dro?d?, D. and Habura, I. and Kronenberg, F. and Prikhodina, L. and van Heel, D. and Fontaine, B. and Cotsapas, C. and Wijmenga, C. and Franke, A. and Annese, V. and Gregersen, P.K. and Parameswaran, S. and Weirauch, M. and Kottyan, L. and Harley, J.B. and Suzuki, H. and Narita, I. and Goto, S. and Lee, H. and Kim, D.K. and Kim, Y.S. and Park, J.-H. and Cho, B. and Choi, M. and van Wijk, A. and Huerta, A. and Ars, E. and Ballarin, J. and Lundberg, S. and Vogt, B. and Mani, L.-Y. and Caliskan, Y. and Barratt, J. and Abeygunaratne, T. and Kalra, P.A. and Gale, D.P. and Panzer, U. and Rauen, T. and Floege, J. and Schlosser, P. and Ekici, A.B. and Eckardt, K.-U. and Chen, N. and Xie, J. and Lifton, R.P. and Loos, R.J.F. and Kenny, E.E. and Ionita-Laza, I. and Köttgen, A. and Julian, B. and Novak, J. and Scolari, F. and Zhang, H. and Gharavi, A.G.
DOI: 10.1101/2021.11.19.21265383
2021

Eculizumab exposure in children and young adults: indications, practice patterns, and outcomes—a Pediatric Nephrology Research Consortium study
Pediatric Nephrology
Muff-Luett, M. and Sanderson, K.R. and Engen, R.M. and Zahr, R.S. and Wenderfer, S.E. and Tran, C.L. and Sharma, S. and Cai, Y. and Ingraham, S. and Winnicki, E. and Weaver, D.J. and Hunley, T.E. and Kiessling, S.G. and Seamon, M. and Woroniecki, R. and Miyashita, Y. and Xiao, N. and Omoloja, A.A. and Kizilbash, S.J. and Mansuri, A. and Kallash, M. and Yu, Y. and Sherman, A.K. and Srivastava, T. and Nester, C.M.
DOI: 10.1007/s00467-021-04965-5
2021

Differences in rituximab use between pediatric rheumatologists and nephrologists for the treatment of refractory lupus nephritis and renal flare in childhood-onset SLE
Pediatric Rheumatology
Gilbert, M. and Goilav, B. and Hsu, J.J. and Nietert, P.J. and Meidan, E. and Chua, A. and Ardoin, S.P. and Wenderfer, S.E. and von Scheven, E. and Ruth, N.M.
DOI: 10.1186/s12969-021-00627-w
2021

Principles of pediatric lupus nephritis in a prospective contemporary multi-center cohort
Lupus
Vazzana, K.M. and Daga, A. and Goilav, B. and Ogbu, E.A. and Okamura, D.M. and Park, C. and Sadun, R.E. and Smitherman, E.A. and Stotter, B.R. and Dasgupta, A. and Knight, A.M. and Hersh, A.O. and Wenderfer, S.E. and Lewandowski, L.B.
DOI: 10.1177/09612033211028658
2021

Renal Survival in Children with Glomerulonephritis with Crescents: A Pediatric Nephrology Research Consortium Cohort Study
Journal of Clinical Medicine
Joseph G. Maliakkal and M. John Hicks and Mini Michael and David T. Selewski and Katherine Twombley and Michelle N Rheault and Meredith Seamon and Jason Misurac and Cheryl L. Tran and Loretta Reyes and Joseph T. Flynn and Ali M. Onder and Alexandru R. Constantinescu and Vaishali Singh and Cynthia Pan and Abiodun Omoloja and Qiang Wu and William E. Smoyer and Guillermo Hidalgo and Scott E. Wenderfer
DOI: 10.3390/jcm9082385
07/2020

Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat
Genes & Immunity
Isha S. Dhande and Sterling C. Kneedler and Yaming Zhu and Aniket S. Joshi and M. John Hicks and Scott E. Wenderfer and Michael C. Braun and Peter A. Doris
DOI: 10.1038/s41435-020-0097-5
05/2020

Approach to Classification and Management of Childhood-Onset Lupus Nephritis
Current Pediatrics Reports
Scott E. Wenderfer and Joyce Chang and M. John Hicks
DOI: 10.1007/s40124-020-00207-8
03/2020

Longitudinal Changes in Health-Related Quality of Life in Primary Glomerular Disease: Results From the CureGN Study
Kidney International Reports
Murphy, S.L. and Mahan, J.D. and Troost, J.P. and Srivastava, T. and Kogon, A.J. and Cai, Y. and Davis, T.K. and Fernandez, H. and Fornoni, A. and Gbadegesin, R.A. and Herreshoff, E. and Canetta, P.A. and Nachman, P.H. and Reeve, B.B. and Selewski, D.T. and Sethna, C.B. and Wang, C.-S. and Bartosh, S.M. and Gipson, D.S. and Tuttle, K.R. and Gharavi, A. and Ahn, W. and Appel, G.B. and Avasare, R.S. and Babayev, R. and Batal, I. and Bomback, A.S. and Brown, E. and Campenot, E.S. and Canetta, P. and Chan, B. and D'Agati, V.D. and Foroncewicz, B. and Ghiggeri, G.M. and Hines, W.H. and Jain, N.G. and Kiryluk, K. and Lin, F. and Lugani, F. and Marasa, M. and Markowitz, G. and Mohan, S. and Mucha, K. and Nickolas, T.L. and Radhakrishnan, J. and Rao, M.K. and Regunathan-Shenk, R. and Sanna-Cherchi, S. and Santoriello, D. and Stokes, M.B. and Yu, N. and Valeri, A.M. and Zviti, R. and Greenbaum, L.A. and Smoyer, W.E. and Al-Uzri, A. and Ashoor, I. and Aviles, D. and Baracco, R. and Barcia, J. and Bartosh, S. and Belsha, C. and Braun, M.C. and Chishti, A. and Claes, D. and Cramer, C. and Davis, K. and Erkan, E. and Feig, D. and Freundlich, M. and Hanna, M. and Hidalgo, G. and Jain, A. and Khalid, M. and Kallash, M. and Lane, J.C. and Mahan, J. and Mathews, N. and Nester, C. and Pan, C. and Patel, H. and Revell, A. and Sreedharan, R. and Steinke, J. and Wenderfer, S.E. and Wong, C.S. and Falk, R. and Cook, W. and Derebail, V. and Fogo, A. and Gasim, A. and Gehr, T. and Harris, R. and Kidd, J. and Laurin, L.-P. and Pendergraft, W. and Pichette, V. and Powell, T.B. and Renfrow, M.B. and Royal, V. and Holzman, L.B. and Adler, S. and Alpers, C. and Matar, R.B. and Brown, E. and Choi, M. and Dell, K.M. and Dukkipati, R. and Fervenza, F.C. and Gadegbeku, C. and Gipson, P. and Hasely, L. and Hingorani, S. and Hladunewich, M.A. and Hogan, J. and Jefferson, J.A. and Jhaveri, K. and Johnstone, D.B. and Kaskel, F. and Kogan, A. and Kopp, J. and Lemley, K.V. and Dieguez, L.M. and Meyers, K. and Neu, A. and O'Shaughnessy, M.M. and O'Toole, J.F. and Parekh, R. and Reich, H. and Reidy, K. and Rondon, H. and Sambandam, K.K. and Sedor, J.R. and Schelling, J. and Sperati, J.C. and Swiatecka-Urban, A. and Trachtman, H. and Weisstuch, J. and Zhdanova, O. and Gillespie, B. and Kretzler, M. and Robinson, B.M. and Mariani, L. and Wladkowski, M. and Guay-Woodford, L.M.
DOI: 10.1016/j.ekir.2020.06.041
2020

Stim1 polymorphism disrupts immune signaling and creates renal injury in hypertension
Journal of the American Heart Association
Dhande, I.S. and Zhu, Y. and Kneedler, S.C. and Joshi, A.S. and Hicks, M.J. and Wenderfer, S.E. and Braun, M.C. and Doris, P.A.
DOI: 10.1161/JAHA.119.014142
2020

Persistent Disease Activity in Patients With Long-Standing Glomerular Disease
Kidney International Reports
Delbarba, E. and Marasa, M. and Canetta, P.A. and Piva, S.E. and Chatterjee, D. and Kil, B.H. and Mu, X. and Gibson, K.L. and Hladunewich, M.A. and Hogan, J.J. and Julian, B.A. and Kidd, J.M. and Laurin, L.-P. and Nachman, P.H. and Rheault, M.N. and Rizk, D.V. and Sanghani, N.S. and Trachtman, H. and Wenderfer, S.E. and Gharavi, A.G. and Bomback, A.S. and Ahn, W. and Appel, G.B. and Babayev, R. and Batal, I. and Brown, E. and Campenot, E.S. and Canetta, P. and Chan, B. and D'Agati, V.D. and Fernandez, H. and Foroncewicz, B. and Ghiggeri, G.M. and Hines, W.H. and Jain, N.G. and Kiryluk, K. and Lau, W.L. and Lin, F. and Lugani, F. and Markowitz, G. and Mohan, S. and Mucha, K. and Nickolas, T.L. and Piva, S. and Radhakrishnan, J. and Rao, M.K. and Sanna-Cherchi, S. and Santoriello, D. and Stokes, M.B. and Yu, N. and Valeri, A.M. and Zviti, R. and Greenbaum, L.A. and Smoyer, W.E. and Al-Uzri, A. and Ashoor, I. and Aviles, D. and Baracco, R. and Barcia, J. and Bartosh, S. and Belsha, C. and Bowers, C. and Braun, M.C. and Chishti, A. and Claes, D. and Cramer, C. and Davis, K. and Erkan, E. and Feig, D. and Freundlich, M. and Gbadegesin, R. and Hanna, M. and Hidalgo, G. and Hunley, T.E. and Jain, A. and Kallash, M. and Khalid, M. and Klein, J.B. and Lane, J.C. and Mahan, J. and Mathews, N. and Nester, C. and Pan, C. and Patterson, L. and Patel, H. and Revell, A. and Silva, C. and Sreedharan, R. and Srivastava, T. and Steinke, J. and Twombley, K. and Vasylyeva, T.L. and Weaver, D.J. and Wong, C.S. and Almaani, S. and Ayoub, I. and Budisavljevic, M. and Derebail, V. and Fatima, H. and Falk, R. and Fogo, A. and Gehr, T. and Gibson, K. and Glenn, D. and Harris, R. and Hogan, S. and Jain, K. and Jennette, J.C. and Julian, B. and Kidd, J. and Massey, H.D. and Mottl, A. and Nachman, P. and Nadasdy, T. and Novak, J. and Parikh, S. and Pichette, V. and Poulton, C. and Powell, T.B. and Renfrow, M. and Rovin, B. and Royal, V. and Saha, M. and Sanghani, N. and Self, S. and Adler, S. and Alpers, C. and Matar, R.B. and Brown, E. and Cattran, D. and Choi, M. and Dell, K.M. and Dukkipati, R. and Fervenza, F.C. and Fornoni, A. and Gadegbeku, C. and Gipson, P. and Hasely, L. and Hingorani, S. and Hogan, J. and Holzman, L.B. and Jefferson, J.A. and Jhaveri, K. and Johnstone, D.B. and Kaskel, F. and Kogan, A. and Kopp, J. and Lafayette, R. and Lemley, K.V. and Malaga-Dieguez, L. and Meyers, K. and Neu, A. and O'Shaughnessy, M.M. and O'Toole, J.F. and Parekh, R. and Reich, H. and Reidy, K. and Rondon, H. and Sambandam, K.K. and Sedor, J.R. and Selewski, D.T. and Sethna, C.B. and Schelling, J. and Sperati, J.C. and Swiatecka-Urban, A. and Tuttle, K.R. and Weisstuch, J. and Vento, S. and Zhdanova, O. and Gillespie, B. and Gipson, D.S. and Hill-Callahan, P. and Helmuth, M. and Herreshoff, E. and Kretzler, M. and Lienczewski, C. and Mansfield, S. and Mariani, L. and Nast, C.C. and Robinson, B.M. and Troost, J. and Wladkowski, M. and Zee, J. and Zinsser, D. and Guay-Woodford, L.M.
DOI: 10.1016/j.ekir.2020.03.017
2020

Establishing core outcome domains in pediatric kidney disease: report of the Standardized Outcomes in Nephrology—Children and Adolescents (SONG-KIDS) consensus workshops
Kidney International
Hanson, C.S. and Craig, J.C. and Logeman, C. and Sinha, A. and Dart, A. and Eddy, A.A. and Guha, C. and Gipson, D.S. and Bockenhauer, D. and Yap, H.-K. and Groothoff, J. and Zappitelli, M. and Webb, N.J.A. and Alexander, S.I. and Furth, S.L. and Samuel, S. and Neu, A. and Viecelli, A.K. and Ju, A. and Sharma, A. and Au, E.H. and Desmond, H. and Shen, J.I. and Manera, K.E. and Azukaitis, K. and Dunn, L. and Carter, S.A. and Gutman, T. and Cho, Y. and Walker, A. and Francis, A. and Sanchez-Kazi, C. and Kausman, J. and Pearl, M. and Benador, N. and Sahney, S. and Tong, A. and Guha, A. and Solarin, A. and Platona, A. and Hamilton, A. and Woods-Barnard, A. and Eddy, A. and Karathanas, A. and Baumgart, A. and Fielding, A. and LePage, A. and Bernier-Jean, A. and Kelly, A. and Teixeira, A. and Matus, A. and Narva, A. and Wang, A.Y.-M. and Fielding, A. and Meza, A. and Fielding, A. and Teixeira-Pinto, A. and Bagga, A. and Jankauskiene, A. and Kelly, A. and Gillespie, B. and Sautenet, B. and Vogt, B. and Foster, B. and Warady, B. and Dixon, B. and Manns, B. and Hemmelgarn, B. and Bscardark, B. and Romeo, B. and Meza, C. and Brockett, C. and Prestidge, C. and Green, C. and Perkins, C. and Schmitt, C.P. and Fielding, C. and Settee, C. and Sumpton, D. and Meza, D. and Karathanas, D. and Harris, D. and Wheeler, D. and Hooper, D. and Geary, D. and Haffner, D. and Mekahli, D. and Drozdz, D. and Romeo, E. and Ku, E. and Urbina, E. and Levtchenko, E. and Balovlenkov, E. and Hodson, E. and Morales, E. and O'Lone, E. and Machuca, E. and Carlton, E. and Olver, E. and Morales, E. and Mirza, F. and Mackie, F. and Tentori, F. and Schaefer, F. and Higgins, G. and Deschenes, G. and Plunkett, G. and Yoder, G. and Wong, G. and Morales, G. and Germino, G. and Perkins, H. and Mitchell-Smith, H. and Coolican, H. and Xu, H. and Anochie, I. and Ha, I.-S. and Davis, I. and Liu, I. and Samaniego, I. and Machuca, J. and Machuca, J. and Kerklaan, J. and Brockett, J. and Norton, J. and Goebel, J. and Rao, J. and Machuca, J. and Mitchell-Smith, J. and Watson, J. and Gill, J. and Flynn, J.T. and Samuels, J. and Bacchetta, J. and Yoder, K. and Twombley, K. and McMichael, K.-A. and Ishikura, K. and Romeo, K. and Settee, K. and Van, K.L. and McMichael, L. and Trinh, L. and Greenbaum, L. and Sanchez, L. and Fielding, L. and Rees, L. and Lippincott, L. and Mejia-Saldivar, L. and Saldivar, L. and Guay-Woodford, L. and Samaniego, L. and Hamiwka, L. and Bell, L. and Barry, L. and Macauley, L. and Holmes, L. and Karathanas, M. and Mitchell-Smith, M. and Walker, M. and Benavides, M. and Tonelli, M. and Ferris, M. and Vivarelli, M. and Wolfenden, M. and Howell, M. and Christian, M. and Schreiber, M. and Moxey-Mims, M. and Leonard, M. and Karathanas, M. and Natatmadja, M. and Brockett, M. and Bonilla-Felix, M. and Atkinson, M. and Baum, M. and Rheault, M. and McCulloch, M. and Matsuda-Abedini, M. and Michael, M. and Khan, M. and Salih, M. and Carlton, M.A. and Plunkett, N. and Webb, N. and Scholes-Robertson, N. and Larkins, N. and Evangelidis, N. and Yoder, N. and Meza, N. and Olver, P. and Carlton, P. and Brophy, P. and Tugwell, P. and Cochat, P. and Mehrotra, R. and Wolfenden, R. and Gbadegesin, R. and Benavides, R. and Johnson, R. and Morales, R. and McGee, R. and Fish, R. and Gardos, R. and Pecoits-Filho, R. and Vargas, R. and Saldivar, R. and Coppo, R. and Shroff, R. and Raina, R. and Youssouf, S. and Crowe, S. and Anumudu, S. and Chan, S. and Baldacchino, S. and Wenderfer, S. and Wolfenden, S. and Carlton, S. and Sutton, S. and Murphy, S. and Teo, S. and Salih, S. and Carlton, S. and Pearson, S. and Khan, S. and Wilson, S. and Sharma, S. and Marks, S. and Cornish, S. and Goldstein, S. and Mendley, S. and Lippincott, S. and Charles, S. and Mitchell-Smith, T. and Harris, T. and Vetter, T. and Carlton, T. and Carlton, T. and Querfeld, U. and Saglimbene, V. and Charles, V. and van Biesen, W. and Winkelmayer, W. and Machuca, Y. and Salih, Y. and Anh, Y.H. and Perkins, Z. and Salih, Z.
DOI: 10.1016/j.kint.2020.05.054
2020

Germ-line genetic variation in the immunoglobulin heavy chain creates stroke susceptibility in the spontaneously hypertensive rat
Physiological Genomics
Isha S. Dhande and Sterling C. Kneedler and Aniket S. Joshi and Yaming Zhu and M. John Hicks and Scott E. Wenderfer and Michael C. Braun and Peter A. Doris
DOI: 10.1152/physiolgenomics.00054.2019
11/2019

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus
Arthritis Care & Research
Hermine I. Brunner and Michael J. Holland and Michael W. Beresford and Stacy P. Ardoin and Simone Appenzeller and Clovis A. Silva and Francisco Flores and Beatrice Goilav and Pinar Ozge Avar Aydin and Scott E. Wenderfer and Deborah M. Levy and Angelo Ravelli and Raju Khubchandani and Tadej Avcin and Marisa S. Klein-Gitelman and Nicolino Ruperto and Brian M. Feldman and Jun Ying and Cristina Battagliotti and Maria Isabel Brusco and Rubén Cuttica and Carmen De Cunto and Graciela Espada and Maximiliano Farfan and Stella Garay and Maria Marcantoni and Alvarez Marcela and Silvia Meiorin and Maria Elena Rama and Ricardo Russo and Carolina Torre Walsh and Celso Zamparo and Navid Adib and Jonathan Akikusa and Christina Boros and Senq J. Lee and Damien Mckay and Susan Piper and Rik Joos and Blanca Bica and Leonardo Campos and André Cavalcanti and Rogerio do Prado and Amanda Donner-Maliki and Taciana Fernandes and Adriana Fonseca and Rozana Gasparello de Almeida and Andressa Guariento and Cather
DOI: 10.1002/acr.23834
05/2019

Lupus Nephritis
Pediatric Clinics of North America
Scott E. Wenderfer and Karen W. Eldin
DOI: 10.1016/j.pcl.2018.08.007
02/2019

Lupus nephritis (including antiphospholipid antibody syndrome), pediatric
Glomerulonephritis
Wenderfer, S.E. and Ruth, N.M.
DOI: 10.1007/978-3-319-49379-4_15
2019

Treatment of Severe Amlodipine Toxicity With Molecular Adsorbent Recirculating System
Kidney International Reports
Pinto, V.L. and Wenderfer, S.E. and Morris, J. and Akcan-Arikan, A.
DOI: 10.1016/j.ekir.2018.09.017
2019

Management and treatment of glomerular diseases (part 2): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Kidney International
Rovin, B.H. and Caster, D.J. and Cattran, D.C. and Gibson, K.L. and Hogan, J.J. and Moeller, M.J. and Roccatello, D. and Cheung, M. and Wheeler, D.C. and Winkelmayer, W.C. and Floege, J. and Adler, S.G. and Alpers, C.E. and Ayoub, I. and Bagga, A. and Barbour, S.J. and Barratt, J. and Chan, D.T.M. and Chang, A. and Choo, J.C.J. and Cook, H.T. and Coppo, R. and Fervenza, F.C. and Fogo, A.B. and Fox, J.G. and Glassock, R.J. and Harris, D. and Hodson, E.M. and Hoxha, E. and Iseki, K. and Jennette, J.C. and Jha, V. and Johnson, D.W. and Kaname, S. and Katafuchi, R. and Kitching, A.R. and Lafayette, R.A. and Li, P.K.T. and Liew, A. and Lv, J. and Malvar, A. and Maruyama, S. and Mejía-Vilet, J.M. and Mok, C.C. and Nachman, P.H. and Nester, C.M. and Noiri, E. and O'Shaughnessy, M.M. and Özen, S. and Parikh, S.M. and Park, H.-C. and Peh, C.A. and Pendergraft, W.F. and Pickering, M.C. and Pillebout, E. and Radhakrishnan, J. and Rathi, M. and Ronco, P. and Smoyer, W.E. and Tang, S.C.W. and Tesa?, V. and Thurman, J.M. and Trimarchi, H. and Vivarelli, M. and Walters, G.D. and Wang, A.Y.-M. and Wenderfer, S.E. and Wetzels, J.F.M.
DOI: 10.1016/j.kint.2018.11.008
2019

Research priorities in childhood-onset lupus: Results of a multidisciplinary prioritization exercise
Pediatric Rheumatology
Ardoin, S.P. and Daly, R.P. and Merzoug, L. and Tse, K. and Ardalan, K. and Arkin, L. and Knight, A. and Rubinstein, T. and Ruth, N. and Wenderfer, S.E. and Hersh, A.O.
DOI: 10.1186/s12969-019-0327-4
2019

Identifying Important Outcomes for Young People With CKD and Their Caregivers: A Nominal Group Technique Study
American Journal of Kidney Diseases
Hanson, C.S. and Gutman, T. and Craig, J.C. and Bernays, S. and Raman, G. and Zhang, Y. and James, L.J. and Ralph, A.F. and Ju, A. and Manera, K.E. and Teixeira-Pinto, A. and Viecelli, A.K. and Alexander, S.I. and Blydt-Hansen, T.D. and Dionne, J. and McTaggart, S. and Michael, M. and Walker, A. and Carter, S. and Wenderfer, S.E. and Winkelmayer, W.C. and Bockenhauer, D. and Dart, A. and Eddy, A.A. and Furth, S.L. and Gipson, D.S. and Goldstein, S.L. and Groothoff, J. and Samuel, S. and Sinha, A. and Webb, N.J.A. and Yap, H.-K. and Zappitelli, M. and Currier, H. and Tong, A.
DOI: 10.1053/j.ajkd.2018.12.040
2019

Health-related quality of life in glomerular disease
Kidney International
Canetta, P.A. and Troost, J.P. and Mahoney, S. and Kogon, A.J. and Carlozzi, N. and Bartosh, S.M. and Cai, Y. and Davis, T.K. and Fernandez, H. and Fornoni, A. and Gbadegesin, R.A. and Herreshoff, E. and Mahan, J.D. and Nachman, P.H. and Selewski, D.T. and Sethna, C.B. and Srivastava, T. and Tuttle, K.R. and Wang, C.-S. and Falk, R.J. and Gharavi, A.G. and Gillespie, B.W. and Greenbaum, L.A. and Holzman, L.B. and Kretzler, M. and Robinson, B.M. and Smoyer, W.E. and Guay-Woodford, L.M. and Reeve, B. and Gipson, D.S. and Ahn, W. and Appel, G.B. and Babayev, R. and Batal, I. and Bomback, A.S. and Brown, E. and Campenot, E.S. and Canetta, P. and Carlassara, L. and Chan, B. and Chatterjee, D. and D'Agati, V.D. and Delbarba, E. and Dogra, S. and Foroncewicz, B. and Ghiggeri, G.M. and Hines, W.H. and Husain, S.A. and Jain, N.G. and Khairallah, P. and Kil, B.H. and Kiryluk, K. and Jeyabalan, A. and Lau, W.L. and Lin, F. and Lugani, F. and Marasa, M. and Markowitz, G. and Mohan, S. and Mu, X. and Mucha, K. and Nickolas, T.L. and Piva, S. and Radhakrishnan, J. and Rao, M.K. and Renu, R.-S. and Sanna-Cherchi, S. and Santoriello, D. and Shirazian, S. and Stokes, M.B. and Uy, N. and Valeri, A.M. and Al-Uzri, A. and Ambruzs, J. and Ashoor, I. and Aviles, D. and Baracco, R. and Barcia, J. and Bartosh, S. and Belsha, C. and Bowers, C. and Braun, M.C. and Chernitskiy, V. and Chishti, A. and Claes, D. and Clark, K. and Cramer, C. and Davis, K. and Erkan, E. and Feig, D. and Freundlich, M. and Gaut, J. and Gbadegesin, R. and Hanna, M. and Hidalgo, G. and Hooper, D. and Hunley, T.E. and Jain, A. and Kallash, M. and Kamel, M. and Khalid, M. and Klein, J.B. and Kump, T. and Lane, J.C. and Liapis, H. and Mahan, J. and Nester, C. and Pan, C. and Patterson, L. and Patel, H. and Raad, A. and Revell, A. and Rheault, M.N. and Silva, C. and Sreedharan, R. and Steinke, J. and Sumner, S. and Twombley, K. and Wenderfer, S.E. and Vasylyeva, T.L. and Weaver, D.J. and Wong, C.S. and Yin, H. and Achanti, A. and Almaani, S. and Ayoub, I. and Budisavljevic, M. and D'Angelo, M. and Fatima, H. and Falk, R. and Fogo, A. and Gibson, K. and Glenn, D. and Hogan, S. and Jennette, J.C. and Julian, B. and Kidd, J. and Laurin, L.-P. and Massey, H.D. and Mottl, A. and Murphy, S. and Nachman, P. and Nadasdy, T. and Novak, J. and Parikh, S. and Poulton, C. and Powell, T.B. and Renfrow, M. and Reynolds, M. and Rizk, D. and Rovin, B. and Royal, V. and Sanghani, N. and Self, S. and Adler, S. and Alachkar, N. and Alpers, C. and Matar, R.B. and Avila-Casado, C. and Bagnasco, S. and Brede, E. and Brown, E. and Cattran, D. and Choi, M. and Dell, K.M. and Dewalt, D. and Denburg, M. and Dukkipati, R. and Fervenza, F.C. and Gadegbeku, C. and Gipson, P. and Gonzalez-Zea, A. and Hasely, L. and Hendren, E. and Hingorani, S. and Hladunewich, M. and Hogan, J. and Hou, J. and Jefferson, J.A. and Jhaveri, K. and Johnstone, D.B. and Kaskel, F. and Kogan, A. and Kopp, J. and Lafayette, R. and Lemley, K.V. and Malaga-Dieguez, L. and Meyers, K. and Neu, A. and O'Shaughnessy, M.M. and O'Toole, J.F. and Oliverio, A. and Palmer, M. and Parekh, R. and Pitter, R. and Reich, H. and Reidy, K. and Rondon, H. and Sambandam, K.K. and Sampson, M. and Sedor, J.R. and Schelling, J. and Sperati, J.C. and Swiatecka-Urban, A. and Trachtman, H. and Waldman, M. and Weisstuch, J. and Wiggins, R. and Williams, D. and Winkler, C. and Vento, S. and Young, E. and Zhdanova, O. and Barisoni, L. and Beil, C. and Eikstadt, R. and Gillespie, B. and Graff, J. and Hewitt, S. and Hill-Callahan, P. and Helmuth, M. and Lienczewski, C. and Mansfield, S. and Mariani, L. and McCullough, K. and Moore, N. and Nast, C.C. and Sexton, M. and Troost, J. and Wladkowski, M. and Zee, J. and Zinsser, D.
DOI: 10.1016/j.kint.2018.12.018
2019

Developing a research mentorship program: The American society of pediatric nephrology's experience
Frontiers in Pediatrics
Vasylyeva, T.L. and Díaz-González de Ferris, M.E. and Hains, D.S. and Ho, J. and Harshman, L.A. and Reidy, K.J. and Brady, T.M. and Okamura, D.M. and Samsonov, D.V. and Wenderfer, S.E. and Hartung, E.A.
DOI: 10.3389/fped.2019.00155
2019

Correction to: Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings (Pediatric Nephrology, (2018), 33, 10, (1773-1780), 10.1007/s00467-018-3994-3)
Pediatric Nephrology
Pelletier, J.H. and Kumar, K.R. and Engen, R. and Bensimhon, A. and Varner, J.D. and Rheault, M.N. and Srivastava, T. and Straatmann, C. and Silva, C. and Davis, T.K. and Wenderfer, S.E. and Gibson, K. and Selewski, D. and Barcia, J. and Weng, P. and Licht, C. and Jawa, N. and Kallash, M. and Foreman, J.W. and Wigfall, D.R. and Chua, A.N. and Chambers, E. and Hornik, C.P. and Brewer, E.D. and Nagaraj, S.K. and Greenbaum, L.A. and Gbadegesin, R.A.
DOI: 10.1007/s00467-018-4103-3
2019

CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease
American Journal of Kidney Diseases
Mariani, L.H. and Bomback, A.S. and Canetta, P.A. and Flessner, M.F. and Helmuth, M. and Hladunewich, M.A. and Hogan, J.J. and Kiryluk, K. and Nachman, P.H. and Nast, C.C. and Rheault, M.N. and Rizk, D.V. and Trachtman, H. and Wenderfer, S.E. and Bowers, C. and Hill-Callahan, P. and Marasa, M. and Poulton, C.J. and Revell, A. and Vento, S. and Barisoni, L. and Cattran, D. and D'Agati, V. and Jennette, J.C. and Klein, J.B. and Laurin, L.-P. and Twombley, K. and Falk, R.J. and Gharavi, A.G. and Gillespie, B.W. and Gipson, D.S. and Greenbaum, L.A. and Holzman, L.B. and Kretzler, M. and Robinson, B. and Smoyer, W.E. and Guay-Woodford, L.M. and Ahn, W. and Appel, G.B. and Babayev, R. and Batal, I. and Brown, E. and Campenot, E.S. and Canetta, P. and Carlassara, L. and Chan, B. and Chatterjee, D. and D'Agati, V.D. and Delbarba, E. and Dogra, S. and Fernandez, H. and Foroncewicz, B. and Ghiggeri, G.M. and Hines, W.H. and Ali Husain, S. and Jain, N.G. and Khairallah, P. and Kil, B.H. and Jeyabalan, A. and Lau, W.L. and Lin, F. and Lugani, F. and Markowitz, G. and Mohan, S. and Mu, X. and Mucha, K. and Nickolas, T.L. and Piva, S. and Radhakrishnan, J. and Rao, M.K. and Regunathan-Shenk, R. and Sanna-Cherchi, S. and Santoriello, D. and Shirazian, S. and Stokes, M.B. and Yu, N. and Valeri, A.M. and Zviti, R. and Al-Uzri, A. and Ambruzs, J. and Ashoor, I. and Aviles, D. and Baracco, R. and Barcia, J. and Bartosh, S. and Belsha, C. and Braun, M.C. and Cai, Y. and Chernitskiy, V. and Chishti, A. and Claes, D. and Clark, K. and Cramer, C. and Davis, K. and Dutcher, A. and Erkan, E. and Feig, D. and Freundlich, M. and Gaut, J. and Gbadegesin, R. and Hanna, M. and Hidalgo, G. and Hooper, D. and Hunley, T.E. and Jain, A. and Kallash, M. and Kamel, M. and Khalid, M. and Kump, T. and Lane, J.C. and Liapis, H. and Mahan, J. and Mathews, N. and Nester, C. and Pan, C. and Patterson, L. and Patel, H. and Raad, A. and Silva, C. and Sreedharan, R. and Srivastava, T. and Steinke, J. and Sumner, S. and Vasylyeva, T.L. and Wang, C.-S. and Weaver, D.J. and Wong, C.S. and Yin, H. and Achanti, A. and Almaani, S. and Ayoub, I. and Budisavljevic, M. and D'Angelo, M. and Derebail, V. and Fatima, H. and Falk, R. and Fogo, A. and Gibson, K. and Glenn, D. and Hogan, S. and Jain, K. and Julian, B. and Kidd, J. and Massey, H.D. and Mottl, A. and Murphy, S. and Nadasdy, T. and Novak, J. and Parikh, S. and Poulton, C. and Powell, T.B. and Reeve, B. and Renfrow, M. and Reynolds, M. and Rovin, B. and Royal, V. and Saha, M. and Sanghani, N. and Self, S. and Adler, S. and Alachkar, N. and Alpers, C. and Matar, R.B. and Avila-Casado, C. and Bagnasco, S. and Brede, E. and Brown, E. and Cattran, D. and Choi, M. and Contreras, G. and Dell, K.M. and Dewalt, D. and Denburg, M. and Dukkipati, R. and Fervenza, F.C. and Fornoni, A. and Gadegbeku, C. and Gipson, P. and Gonzalez-Zea, A. and Hasely, L. and Hendren, E. and Hingorani, S. and Hogan, J. and Hou, J. and Jefferson, J.A. and Jhaveri, K. and Johnstone, D.B. and Kaskel, F. and Kogan, A. and Kopp, J. and Lafayette, R. and Lemley, K.V. and Malaga-Dieguez, L. and Meyers, K. and Neu, A. and O'Shaughnessy, M.M. and O'Toole, J.F. and Oliverio, A. and Palmer, M. and Parekh, R. and Pitter, R. and Reich, H. and Reidy, K. and Rondon, H. and Sambandam, K.K. and Sampson, M. and Sedor, J.R. and Selewski, D.T. and Sethna, C.B. and Schelling, J. and Sperati, J.C. and Swiatecka-Urban, A. and Tuttle, K.R. and Waldman, M. and Weisstuch, J. and Wiggins, R. and Williams, D. and Winkler, C. and Young, E. and Zhdanova, O. and Beil, C. and Eikstadt, R. and Gillespie, B. and Graff, J. and Hewitt, S. and Herreshoff, E. and Lienczewski, C. and Mansfield, S. and Mariani, L. and McCullough, K. and Moore, N. and Robinson, B.M. and Sexton, M. and Troost, J. and Wladkowski, M. and Zee, J. and Zinsser, D.
DOI: 10.1053/j.ajkd.2018.07.020
2019

Management and treatment of glomerular diseases (part 1): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Kidney International
Floege, J. and Barbour, S.J. and Cattran, D.C. and Hogan, J.J. and Nachman, P.H. and Tang, S.C.W. and Wetzels, J.F.M. and Cheung, M. and Wheeler, D.C. and Winkelmayer, W.C. and Rovin, B.H. and Adler, S.G. and Alpers, C.E. and Ayoub, I. and Bagga, A. and Barratt, J. and Caster, D.J. and Chan, D.T.M. and Chang, A. and Choo, J.C.J. and Cook, H.T. and Coppo, R. and Fervenza, F.C. and Fogo, A.B. and Fox, J.G. and Gibson, K.L. and Glassock, R.J. and Harris, D. and Hodson, E.M. and Hoxha, E. and Iseki, K. and Jennette, J.C. and Jha, V. and Johnson, D.W. and Kaname, S. and Katafuchi, R. and Kitching, A.R. and Lafayette, R.A. and Li, P.K.T. and Liew, A. and Lv, J. and Malvar, A. and Maruyama, S. and Mejía-Vilet, J.M. and Moeller, M.J. and Mok, C.C. and Nester, C.M. and Noiri, E. and O'Shaughnessy, M.M. and Özen, S. and Parikh, S.M. and Park, H.-C. and Peh, C.A. and Pendergraft, W.F. and Pickering, M.C. and Pillebout, E. and Radhakrishnan, J. and Rathi, M. and Roccatello, D. and Ronco, P. and Smoyer, W.E. and Tesa?, V. and Thurman, J.M. and Trimarchi, H. and Vivarelli, M. and Walters, G.D. and Wang, A.Y.-M. and Wenderfer, S.E.
DOI: 10.1016/j.kint.2018.10.018
2019

Pediatric Nephrology and Rheumatology Practice Patterns in Granulomatosis with Polyangiitis: A Midwest Pediatric Nephrology Consortium Study
International Journal of Nephrology
Cristin D. W. Kaspar and Keia Sanderson and Seza Ozen and Priya S. Verghese and Megan Lo and Timothy E. Bunchman and Scott E. Wenderfer and Jason Kidd
DOI: 10.1155/2018/8413096
08/2018

50 Years Ago in The Journal of Pediatrics
The Journal of Pediatrics
Joseph L. Alge and Scott E. Wenderfer
DOI: 10.1016/j.jpeds.2017.12.030
06/2018

American College of Rheumatology Provisional Criteria for Global Flares in Childhood-Onset Systemic Lupus Erythematosus
Arthritis Care & Research
Hermine I. Brunner and Michael Holland and Michael W. Beresford and Stacy P. Ardoin and Simone Appenzeller and Clovis A. Silva and Francisco Flores and Beatrice Goilav and Scott E. Wenderfer and Deborah M. Levy and Angelo Ravelli and Raju Khunchandani and Tadej Avcin and Marisa S. Klein-Gitelman and Brian M. Feldman and Nicolino Ruperto and Jun Ying
DOI: 10.1002/acr.23557
06/2018

Recurrence of nephrotic syndrome following kidney transplantation is associated with initial native kidney biopsy findings
Pediatric Nephrology
Pelletier, J.H. and Kumar, K.R. and Engen, R. and Bensimhon, A. and Varner, J.D. and Rheault, M.N. and Srivastava, T. and Straatmann, C. and Silva, C. and Davis, T.K. and Wenderfer, S.E. and Gibson, K. and Selewski, D. and Barcia, J. and Weng, P. and Licht, C. and Jawa, N. and Kallash, M. and Foreman, J.W. and Wigfall, D.R. and Chua, A.N. and Chambers, E. and Hornik, C.P. and Brewer, E.D. and Nagaraj, S.K. and Greenbaum, L.A. and Gbadegesin, R.A.
DOI: 10.1007/s00467-018-3994-3
2018

Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study
Kidney International Reports
Selewski, D.T. and Ambruzs, J.M. and Appel, G.B. and Bomback, A.S. and Matar, R.B. and Cai, Y. and Cattran, D.C. and Chishti, A.S. and D'Agati, V.D. and D'Alessandri-Silva, C.J. and Gbadegesin, R.A. and Hogan, J.J. and Iragorri, S. and Jennette, J.C. and Julian, B.A. and Khalid, M. and Lafayette, R.A. and Liapis, H. and Lugani, F. and Mansfield, S.A. and Mason, S. and Nachman, P.H. and Nast, C.C. and Nester, C.M. and Noone, D.G. and Novak, J. and O'Shaughnessy, M.M. and Reich, H.N. and Rheault, M.N. and Rizk, D.V. and Saha, M.K. and Sanghani, N.S. and Sperati, C.J. and Sreedharan, R. and Srivastava, T. and Swiatecka-Urban, A. and Twombley, K. and Vasylyeva, T.L. and Weaver, D.J. and Yin, H. and Zee, J. and Falk, R.J. and Gharavi, A.G. and Gillespie, B.W. and Gipson, D.S. and Greenbaum, L.A. and Holzman, L.B. and Kretzler, M. and Robinson, B.M. and Smoyer, W.E. and Flessner, M. and Guay-Woodford, L.M. and Kiryluk, K. and Ahn, W. and Avasare, R.S. and Babayev, R. and Batal, I. and Brown, E. and Campenot, E.S. and Canetta, P. and Chan, B. and Fernandez, H. and Foroncewicz, B. and Ghiggeri, G.M. and Hines, W.H. and Jain, N.G. and Lin, F. and Marasa, M. and Markowitz, G. and Mohan, S. and Mucha, K. and Nickolas, T.L. and Radhakrishnan, J. and Rao, M.K. and Regunathan-Shenk, R. and Sanna-Cherchi, S. and Santoriello, D. and Stokes, M.B. and Yu, N. and Valeri, A.M. and Zviti, R. and Al-Uzri, A. and Ashoor, I. and Aviles, D. and Baracco, R. and Barcia, J. and Bartosh, S. and Belsha, C. and Braun, M.C. and Claes, D. and Cramer, C. and Davis, K. and Erkan, E. and Feig, D. and Freundlich, M. and Hanna, M. and Hidalgo, G. and Jain, A. and Kallash, M. and Lane, J.C. and Mahan, J. and Mathews, N. and Pan, C. and Patel, H. and Revell, A. and Steinke, J. and Wenderfer, S.E. and Wong, C.S. and Cook, W. and Derebail, V. and Fogo, A. and Gasim, A. and Gehr, T. and Harris, R. and Kidd, J. and Laurin, L.-P. and Pendergraft, W. and Pichette, V. and Powell, T.B. and Renfrow, M.B. and Royal, V. and Adler, S. and Alpers, C. and Choi, M. and Dell, K.M. and Dukkipati, R. and Fervenza, F.C. and Fornoni, A. and Gadegbeku, C. and Gipson, P. and Hasely, L. and Hingorani, S. and Hladunewich, M.A. and Jefferson, J.A. and Jhaveri, K. and Johnstone, D.B. and Kaskel, F. and Kogan, A. and Kopp, J. and Lemley, K.V. and Dieguez, L.M. and Meyers, K. and Neu, A. and O'Toole, J.F. and Parekh, R. and Reidy, K. and Rondon, H. and Sambandam, K.K. and Sedor, J.R. and Sethna, C.B. and Schelling, J. and Trachtman, H. and Tuttle, K.R. and Weisstuch, J. and Zhdanova, O. and Barisoni, L. and Mariani, L. and Wladkowski, M.
DOI: 10.1016/j.ekir.2018.07.021
2018

Susceptibility to hypertensive renal disease in the spontaneously hypertensive rat is influenced by 2 loci affecting blood pressure and immunoglobulin repertoire
Hypertension
Dhande, I.S. and Cranford, S.M. and Zhu, Y. and Kneedler, S.C. and Hicks, M.J. and Wenderfer, S.E. and Braun, M.C. and Doris, P.A.
DOI: 10.1161/HYPERTENSIONAHA.117.10593
2018

Child and Parental Perspectives on Communication and Decision Making in Pediatric CKD: A Focus Group Study
American Journal of Kidney Diseases
Gutman, T. and Hanson, C.S. and Bernays, S. and Craig, J.C. and Sinha, A. and Dart, A. and Eddy, A.A. and Gipson, D.S. and Bockenhauer, D. and Yap, H.-K. and Groothoff, J. and Zappitelli, M. and Webb, N.J.A. and Alexander, S.I. and Goldstein, S.L. and Furth, S. and Samuel, S. and Blydt-Hansen, T. and Dionne, J. and Michael, M. and Wenderfer, S.E. and Winkelmayer, W.C. and Currier, H. and McTaggart, S. and Walker, A. and Ralph, A.F. and Ju, A. and James, L.J. and Carter, S. and Tong, A.
DOI: 10.1053/j.ajkd.2018.05.005
2018

Evolving epidemiology of pediatric glomerular disease
Clinical Journal of the American Society of Nephrology
Rheault, M.N. and Wenderfer, S.E.
DOI: 10.2215/CJN.06220518
2018

Measuring Disease Damage and Its Severity in Childhood-Onset Systemic Lupus Erythematosus
Arthritis Care and Research
Holland, M.J. and Beresford, M.W. and Feldman, B.M. and Huggins, J. and Norambuena, X. and Silva, C.A. and Susic, G. and Sztajnbok, F. and Uziel, Y. and Appenzeller, S. and Ardoin, S.P. and Avcin, T. and Flores, F. and Goilav, B. and Khubchandani, R. and Klein-Gitelman, M. and Levy, D. and Ravelli, A. and Wenderfer, S.E. and Ying, J. and Ruperto, N. and Brunner, H.I.
DOI: 10.1002/acr.23531
2018

Clinical presentation and outcomes of childhood-onset membranous lupus nephritis
Pediatric Nephrology
Maria Pereira and Eyal Muscal and Karen Eldin and M. John Hicks and Anna Carmela P. Sagcal-Gironella and Marietta DeGuzman and Scott E. Wenderfer
DOI: 10.1007/s00467-017-3743-z
12/2017

Glomerular Diseases in Children
Advances in Chronic Kidney Disease
Scott E. Wenderfer and Joseph P. Gaut
DOI: 10.1053/j.ackd.2017.09.005
11/2017

Mycophenolate mofetil prevents cerebrovascular injury in stroke-prone spontaneously hypertensive rats
Physiological Genomics
Isha S. Dhande and Yaming Zhu and Michael C. Braun and M. John Hicks and Scott E. Wenderfer and Peter A. Doris
DOI: 10.1152/physiolgenomics.00110.2016
03/2017

Changes in frequency and activation status of major CD4+ T-cell subsets after initiation of immunosuppressive therapy in a patient with new diagnosis childhood-onset systemic lupus erythematosus
Frontiers in Pediatrics
Singla, S. and Wenderfer, S.E. and Muscal, E. and Sagcal-Gironella, A.C.P. and Orange, J.S. and Makedonas, G.
DOI: 10.3389/fped.2017.00104
2017

Clinical characteristics of children with membranous lupus nephritis: The Childhood Arthritis and Rheumatology Research Alliance Legacy Registry
Lupus
Boneparth, A. and Wenderfer, S.E. and Moorthy, L.N. and Radhakrishna, S.M. and Sagcal-Gironella, A.C.P. and Von Scheven, E.
DOI: 10.1177/0961203316662720
2017

Advances in the care of children with lupus nephritis
Pediatric Research
Wenderfer, S.E. and Ruth, N.M. and Brunner, H.I.
DOI: 10.1038/pr.2016.247
2017

Approach to membranous lupus nephritis: A survey of pediatric nephrologists and pediatric rheumatologists
Journal of Rheumatology
Boneparth, A. and Radhakrishna, S.M. and Greenbaum, L.A. and Yen, E. and Okamura, D.M. and Cooper, J.C. and Mason, S. and Levy, D.M. and Sule, S.D. and Jensen, P.T. and Yildirim-Toruner, C. and Ardoin, S.P. and Wenderfer, S.E.
DOI: 10.3899/jrheum.170502
2017

Hemolytic uremic syndrome as the presenting manifestation of WT1 mutation and Denys-Drash syndrome: A case report
BMC Nephrology
Alge, J.L. and Wenderfer, S.E. and Hicks, J. and Bekheirnia, M.R. and Schady, D.A. and Kain, J.S. and Braun, M.C.
DOI: 10.1186/s12882-017-0643-1
2017

Renal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia
Pediatric Blood and Cancer
Potter, S.L. and Venkatramani, R. and Wenderfer, S. and Graham, B.H. and Vasudevan, S.A. and Sher, A. and Wu, H. and Wheeler, D.A. and Yang, Y. and Eng, C.M. and Gibbs, R.A. and Roy, A. and Plon, S.E. and Parsons, D.W.
DOI: 10.1002/pbc.26286
2017

Ambulatory blood pressure, left ventricular hypertrophy, and allograft function in children and young adults after kidney transplantation
Transplantation
Hamdani, G. and Nehus, E.J. and Hanevold, C.D. and Van Sickle, J.S. and Woroniecki, R. and Wenderfer, S.E. and Hooper, D.K. and Blowey, D. and Wilson, A. and Warady, B.A. and Mitsnefes, M.M.
DOI: 10.1097/TP.0000000000001087
2017

Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene
Genetics in Medicine
Bekheirnia, M.R. and Bekheirnia, N. and Bainbridge, M.N. and Gu, S. and Akdemir, Z.H.C. and Gambin, T. and Janzen, N.K. and Jhangiani, S.N. and Muzny, D.M. and Michael, M. and Brewer, E.D. and Elenberg, E. and Kale, A.S. and Riley, A.A. and Swartz, S.J. and Scott, D.A. and Yang, Y. and Srivaths, P.R. and Wenderfer, S.E. and Bodurtha, J. and Applegate, C.D. and Velinov, M. and Myers, A. and Borovik, L. and Craigen, W.J. and Hanchard, N.A. and Rosenfeld, J.A. and Lewis, R.A. and Gonzales, E.T. and Gibbs, R.A. and Belmont, J.W. and Roth, D.R. and Eng, C. and Braun, M.C. and Lupski, J.R. and Lamb, D.J.
DOI: 10.1038/gim.2016.131
2017

Nocturnal Hypertension and Attenuated Nocturnal Blood Pressure Dipping is Common in Pediatric Lupus [version 2; referees: 2 approved, 1 approved with reservations]
J. Fallon Campbell and Sarah J. Swartz and Scott E. Wenderfer
DOI: 10.12688/f1000research.6532.2
11/2015

Nocturnal Hypertension and Attenuated Nocturnal Blood Pressure Dipping is Common in Pediatric Lupus [v1; ref status: awaiting peer review, http://f1000r.es/5es]
J. Fallon Campbell and Sarah J. Swartz and Scott E. Wenderfer
DOI: 10.12688/f1000research.6532.1
06/2015

Practice patterns and approach to kidney biopsy in lupus: a collaboration of the Midwest pediatric nephrology consortium and the childhood arthritis and rheumatology research alliance
Pediatr Rheumatol
Scott E. Wenderfer and Jerome C. Lane and Ibrahim F. Shatat and Emily von Scheven and Natasha M. Ruth
DOI: 10.1186/s12969-015-0024-x
06/2015

High Titer Anti-Basement Membrane Antibodies in a Subset of Patients with Pediatric Systemic Lupus Erythematosus
Am J Nephrol
Alvaro Orjuela and Adisak Suwanichkul and Debra Canter and Charles G. Minard and Sridevi Devaraj and M. John Hicks and Eyal Muscal and Scott E. Wenderfer
DOI: 10.1159/000381965
04/2015

Viral-associated glomerulopathies in children
Pediatr Nephrol
Scott E. Wenderfer
DOI: 10.1007/s00467-015-3057-y
03/2015

Hypertensive Renal Injury Is Associated With Gene Variation Affecting Immune Signaling
Circulation: Cardiovascular Genetics
M. C. Braun and S. M. Herring and N. Gokul and M. Monita and R. Bell and Y. Zhu and M. L. Gonzalez-Garay and S. E. Wenderfer and P. A. Doris
DOI: 10.1161/circgenetics.114.000533
11/2014

A69: Lupus Nephritis and Autoantibody Characteristics of a Single Center Cohort of Male Pediatric SLE Patients
Arthritis & Rheumatology
Scott E. Wenderfer and Debra Canter and Marietta DeGuzman and Eyal Muscal
DOI: 10.1002/art.38485
03/2014

A53: Natural History of Pediatric Class V Membranous Lupus Nephritis-A Serial Biopsy Study
Arthritis & Rheumatology
Debra Canter and Karen Eldin and M. John Hicks and Eyal Muscal and Marietta DeGuzman and Scott E. Wenderfer
DOI: 10.1002/art.38469
03/2014

Differential expression of functional Fc-receptors and additional immune complex receptors on mouse kidney cells
Molecular Immunology
Adisak Suwanichkul and Scott E. Wenderfer
DOI: 10.1016/j.molimm.2013.05.219
2013

Hypertensive renal disease
Journal of Hypertension
Michael C. Braun and Stacy M. Herring and Nisha Gokul and Monique Monita and Rebecca Bell and M. John Hicks and Scott E. Wenderfer and Peter A. Doris
DOI: 10.1097/hjh.0b013e328362f9a5
2013

Can inhibition of proteasomes or NF-kappaB help control idiopathic nephrotic syndrome?
Nephrology Dialysis Transplantation
S. E. Wenderfer
DOI: 10.1093/ndt/gfs079
04/2012

Acute Glomerulonephritis
Scott E. Wenderfer
DOI: 10.1142/9789814327565_0011
2012

Intravenous Immunoglobulin in the Management of Lupus Nephritis
Autoimmune Disease
Scott E. Wenderfer
DOI: 10.1155/2012/589359
2012

349 Fc-Receptors and Novel Immunoglobulin Receptors Mediate Immune Complex Binding to Mesangial Cells and Renal Endothelial Cells
American Journal of Kidney Diseases
Raquel Gonzalez and Scott Wenderfer
DOI: 10.1053/j.ajkd.2011.02.352
04/2011

Immunoglobulin Locus Associates with Serum IgG Levels and Albuminuria
Journal of the American Society of Nephrology
S. M. Herring and N. Gokul and M. Monita and R. Bell and E. Boerwinkle and S. E. Wenderfer and M. C. Braun and P. A. Doris
DOI: 10.1681/asn.2010111148
03/2011

C1q nephropathy in the pediatric population: pathology and pathogenesis
Pediatric Nephrology
Scott E. Wenderfer
DOI: 10.1007/s00467-009-1429-x
2010

Urine Proteome Analysis in Murine Nephrotoxic Serum Nephritis
American Journal of Nephrology
Scott E. Wenderfer
DOI: 10.1159/000242430
2009

C3a receptor deficiency accelerates the onset of renal injury in the MRL/lpr mouse
Molecular Immunology
Scott E. Wenderfer
DOI: 10.1016/j.molimm.2008.12.004
2008

Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist
Kidney International
Scott E. Wenderfer
DOI: 10.1038/ki.2008.396
2008

Analysis of C4 and the C4 binding protein in the MRL/lpr mouse
Molecular Immunology
Scott E. Wenderfer
DOI: 10.1186/ar2320
2007

Mice with combined C4 binding protein and factor H deficiency develop progressive lethal renal disease
Arthritis Research and Therapy
Scott E. Wenderfer
DOI: 10.1016/j.molimm.2008.08.019
2007

Cytomegalovirus and Recurrent Idiopathic Membranoproliferative Glomerulonephritis Type 1: Cause or Consequence?
Transplantation
Scott E. Wenderfer
DOI: 10.1097/01.tp.0000251362.75382.18
2007

A reciprocal role for the C3a and C5a receptors in glomerular injury in the factor H deficient mouse
Molecular Immunology
Scott E. Wenderfer
DOI: 10.1016/j.molimm.2006.07.109
2006

C5a Receptor Deficiency Attenuates T Cell Function and Renal Disease in MRLlpr Mice
Journal of the American Society of Nephrology
S. E. Wenderfer
DOI: 10.1681/asn.2005040373
2005

Exon Trapping for Positional Cloning and Fingerprinting
Bacterial Artificial Chromosomes
Scott E. Wenderfer and John J. Monaco
DOI: 10.1385/1-59259-753-x:007
03/2004

Exon Trapping for Positional Cloning and Fingerprinting
Methods in Molecular Biology
Scott E. Wenderfer
DOI: 10.1385/1-59259-753-X:007
03/2004

Exon trapping for positional cloning and fingerprinting.
Methods in molecular biology (Clifton, N.J.)
Wenderfer, S.E. and Monaco, J.J.
2004

Identification of 40 Genes on a 1-Mb Contig around the IL-4 Cytokine Family Gene Cluster on Mouse Chromosome 11
Genomics
Scott E. Wenderfer
DOI: 10.1006/geno.1999.6100
2000

Sequence, linkage to H2-K , and function of mouse tapasin in MHC class I assembly
Immunogenetics
Scott E. Wenderfer
DOI: 10.1007/s002510050430
08/1998

Research

The Wenderfer Laboratory
The Wenderfer Laboratory is interested in immune complex kidney injury, such as those that occur in lupus nephritis and kidney vasculitis. Other immune-mediated kidney diseases share similarities with lupus nephritis but manifest in different ways: IgA nephropathy, crescentic glomerulonephritis, nephrotic syndrome, C3 glomerulopathy, and C1q nephropathy. Understanding the differences in pathogenic mechanisms of disease is critical to developing better diagnostic approaches and optimal diseases management strategies.

Learning health systems for pediatric lupus research
This study utilized the Pediatric Center of Excellence in Nephrology at CHOP in Philadelphia, to identify and validate algorithms for systemic lupus erythematosus (SLE) and lupus nephritis in a large learning health system (LHS), namely PEDSnet. The study was funded by a P50 award from the NIDDK at the National Institutes of Health. Future directions include using these algorithms for comparative effectiveness research on pharmacologic treatment strategies for childhood-onset lupus.

The Childhood Arthritis and Rheumatology Research Alliance (CARRA)
This was funded by the Lupus Foundation of America (LFA) to perform two projects involving childhood-onset lupus nephritis: (1) Advancing therapeutic strategies for management of LN in cSLE study surveyed 185 pediatric rheumatologists and 40 pediatric nephrologists from across North America, on the use of low dose cyclophosphamide in the treatment of LN in childhood-onset SLE. (2) Utilizing the CARRA lupus registry to validate historic principles of lupus nephritis in 216 children with SLE and LN. Future directions include updating CARRA’s consensus treatment plan for lupus nephritis to include a low dose cyclophosphamide arm.

The C1q Nephropathy Study
This study was funded by NephCure Kidney International, a foundation dedicated to advancing the lives of patients with nephrotic syndrome. C1q Nephropathy is similar to lupus nephritis, and to minimal change nephrotic syndrome (MCNS) and focal segmental glomerulosclerosis (FSGS). We identified a cohort of patients with C1q Nephropathy from the CureGN and NEPTUNE studies to compare the natural histories, outcomes, histopathology, and genomics of this disease with FSGS and MCNS. Future directions include comparing C1q nephropathy to forms of lupus nephritis.

A Randomized, Multicenter, Double-blind, Parallel, Active-control Study of the Effects of Sparsentan, a Dual Endothelin Receptor and Angiotensin Receptor Blocker, on Renal Outcomes in Patients With Primary FSGS
This phase 3 clinical trial is sponsored by Travere Therapeutics (NCT03493685). The DUET study was a phase II trial of sparsentan which met its primary end point in adults and children age 8-75 years old with focal segmental glomerulosclerosis (FSGS). Most patients with FSGS are refractory to other pharmacotherapeutics. I was the site investigator at Texas Children’s Hospital, an enrolling site for children 8-18 years. Future directions include providing children in British Columbia with access to the latest kidney disease or kidney transplant trials at BC Children’s Hospital.

Honours & Awards

Star Award for Clinical Excellence, Baylor College of Medicine, 2021

The CureGN Award, Nephcure Kidney International, 2020

Dean’s Teaching Award, The University of Texas Health Science Center, 2011

Victor Chaltiel Young Investigator Award, National Kidney Foundation, 2009