Overview

My areas of research interest lies within the area of pediatric drug allergy. Many patients labelled as allergic to medications are not actually allergic – this has significant impact on medication selection for subsequent illnesses, and leads to less optimal medication being prescribed to the patient at increased costs to the health care system. This is of particular concern in patients with complex medical needs who often require admission to hospital or treatment with medications. I hope that by developing a program aimed at clarifying the nature of reactions and de-labeling allergy, we can optimize medication selection and patient care, both in hospital and in the community.

I am also involved in projects involving a variety of aspects of food allergy, including optimizing management of allergic reactions by patients/families and describing unusual cases of food allergy in pediatrics.

Publications

Impact of supervised epinephrine autoinjector administration during food challenges on parent confidence
Annals of Allergy, Asthma & Immunology
Timothy Teoh and Christopher Mill and Tiffany Wong and Ingrid Baerg and Angela Alexander and Kyla J. Hildebrand and John Dean and Boris Kuzeljevic and Edmond S. Chan
DOI: 10.1016/j.anai.2016.02.020
05/2016

Combined Autoimmune Cytopenias Presenting in Childhood
Pediatr Blood Cancer
Ibrahim Al Ghaithi and Nicola A.M. Wright and Vicky R. Breakey and Kelly Cox and Ashley Warias and Tiffany Wong and Colleen O'Connell and Victoria Price
DOI: 10.1002/pbc.25769
09/2015

IgE Mediated allergy to wheat in a child with celiac disease
Allergy, Asthma & Clinical Immunology
Tiffany Wong and Edmond S Chan
DOI: 10.1186/1710-1492-10-s1-a37
2014

Epinephrine auto injector administration by parents or patients for anaphylaxis during supervised oral food challenges and assessment of confidence
Allergy, Asthma & Clinical Immunology
Ingrid Baerg and Angela Alexander and Tiffany Wong and Timothy Teoh and Kyla Hildebrand and Sara Leo and Joanne Yeung and John Dean and Edmond Chan
DOI: 10.1186/1710-1492-10-s2-a2
2014

IgE-Mediated allergy to wheat in a child with celiac disease – a case report
Allergy, Asthma & Clinical Immunology
Tiffany Wong and Hin Ko and Edmond S Chan
DOI: 10.1186/1710-1492-10-56
2014

Combined and alternating paracetamol and ibuprofen therapy for febrile children
Cochrane Database of Systematic Reviews
Tiffany Wong and Antonia S Stang and Heather Ganshorn and Lisa Hartling and Ian K Maconochie and Anna M Thomsen and David W Johnson
DOI: 10.1002/14651858.cd009572.pub2
10/2013

Delayed Introduction of Food and Effect On Incidence of Food Allergy in a Population At High Risk for Atopy: The Canadian Asthma Primary Prevention Study (CAPPS)
Journal of Allergy and Clinical Immunology
Tiffany Wong and Moira Chan-Yeung and Roxanne Rousseau and Anne Dybuncio and Anita L. Kozyrskyj and Clare Ramsey and Allan Becker and Edmond S. Chan
DOI: 10.1016/j.jaci.2012.12.1013
02/2013

Human primary immunodeficiencies causing defects in innate immunity
Current Opinion in Allergy and Clinical Immunology
Tiffany Wong and Joanne Yeung and Kyla J. Hildebrand and Anne K. Junker and Stuart E. Turvey
DOI: 10.1097/aci.0000000000000010
2013

Combined and alternating paracetamol and ibuprofen therapy for fever in children
Cochrane Database of Systematic Reviews
Tiffany Wong and David W Johnson and Heather Ganshorn and Ian K Maconochie and Lisa Hartling and Antonia S. Stang
DOI: 10.1002/14651858.cd009572
01/2012

Outcome of diagnostic intervention predicts health-related quality of life scores among children with food allergy
Allergy, Asthma & Clinical Immunology
Linda Kirste and Tim K Takaro and Boris Kuzeljevic and Tiffany Wong and Edmond S Chan
DOI: 10.1186/1710-1492-8-s1-a9
2012

The impact of ongoing illicit drug use on methadone adherence in illicit drug users receiving treatment for HIV in a directly observed therapy program
Drug and Alcohol Dependence
Jesse D. Raffa and Jason Grebely and Harout Tossonian and Tiffany Wong and Mark Viljoen and Milan Khara and Annabel Mead and Mark McLean and Fiona Duncan and A. John Petkau
DOI: 10.1016/j.drugalcdep.2007.02.007
07/2007

Competitive Displacement of Clozapine from Plasma Proteins in Normolipidemic and Hyperlipidemic Plasma Samples: Clinical Implications
LDDI
Ric Procyshyn and Tiffany Ho and Kishor Wasan
DOI: 10.1081/ddc-200054305
05/2005

The Effects of Competitive Displacement on Haloperidol's Plasma Distribution in Normolipidemic and Hyperlipidemic Plasma
Drug Development and Industrial Pharmacy
Ric M. Procyshyn and Tiffany Ho and Kishor M. Wasan
DOI: 10.1080/03639040500272058
01/2005

Research

Epinephrine Autoinjector Study
Families in Pediatric Allergy Clinic often report that they are fearful of using an epinephrine autoinjector despite receiving education on indications for use and technique. It is very important that patients and caregivers have the skills, knowledge and confidence to administer the epinephrine autoinjector when indicated. The goal of this study is to assess the impact of self or caregiver-administrated epinephrine in a medically supervised setting on the confidence of patient and/or caregivers for future use of epinephrine autoinjector.

Penicillin de-labelling Study:
Penicillin allergy is a common drug allergy diagnosis. However, upon assessment by Allergists, many people are not actually allergic. Patients can be erroneously labelled as allergic due to misclassification of a suspected reaction. As a result, many patients will receive alternative antibiotics that are more expensive, potentially less effective, more toxic, and may increase risk of antibiotic resistance. The goal of this study is to develop assessment tools and a program to help pediatric health care providers identify those who are at low risk of penicillin allergy and de-label them.

Research Group Members

Lisa Wilson, Clinic Secretary