Ali Amid

MD

Investigator and Pediatric Hematologist/Oncologist, BC Children's Hospital

Dr. Amid received his medical degree from the Tehran University of Medical Sciences and completed his pediatric residency at the University of Calgary, followed by his pediatric hematology/oncology fellowship at the University of Ottawa and University of Toronto. Dr. Amid subsequently completed a clinical and research fellowship in hemoglobinopathies and iron overload disorders at the Hospital for Sick Children (SickKids) in Toronto. Prior to moving to Vancouver and starting his current role as a Pediatric Hematologist at BC Children’s Hospital in 2021, he was an Assistant Professor of Pediatrics at the University of Ottawa and a Pediatric Hematologist at Children’s Hospital of Eastern Ontario.

A BC Children's Hospital, he is the Director of the Hemoglobinopathy and Iron Overload Clinic.

Academic Affiliations

  • Clinical Associate Professor, Division of Hematology, Oncology & BMT, Department of Pediatrics, Faculty of Medicine, University of British Columbia
  • Research Theme: Childhood Diseases
  • Research Group(s): Childhood Cancer and Blood Research; Clinical Practice, Outcomes and Innovation; Global Health and Innovations; Rare Diseases

Contact Information

Assistant

Carla Willems

cwillems@cw.bc.ca

Location

4480 Oak Street, Vancouver, British Columbia, Canada, V6H 3V4

Outcomes and risk factors for complications in deletional haemoglobin H disease: A retrospective longitudinal cohort study in British Columbia, Canada

British Journal of Haematology

Jacqueline Blunt and Melissa Braschel and Heather McCartney and Navdeep Sandhu and Hayley Merkeley and Ali Amid

DOI: 10.1111/bjh.70123

11 / 2025

Morphologic and Electrophoretic Features of Hemoglobin Bart's Hydrops Fetalis

eJHaem

Ali Amid and Elona Turley and Nicholas Au and Audi Setiadi

DOI: 10.1002/jha2.70077

08 / 2025

Pegcetacoplan for Breakthrough Hemolysis in an Adolescent With Classical Paroxysmal Nocturnal Hemoglobinuria on Eculizumab

Pediatric Blood & Cancer

Catherine Njeru and Danielle Baker and Hayley Merkeley and Ali Amid

DOI: 10.1002/pbc.31649

05 / 2025

Evaluation of low-cost techniques to detect sickle cell disease and -thalassemia: an open-label, international, multicentre study

The Lancet Regional Health - Southeast Asia

Pranav Shrestha and Hendrik Lohse and Christopher Bhatla and Heather McCartney and Alaa Alzaki and Navdeep Sandhu and Pardip Kumar Oli and Sanjeev Chaudhary and Ali Amid and Rodrigo Onell and Nicholas Au and Hayley Merkeley and Videsh Kapoor and Rajan Pande and Boris Stoeber

DOI: 10.1016/j.lansea.2025.100571

04 / 2025

Folic acid supplementation in children with sickle cell disease: A randomized double-blind non-inferiority crossover trial.

The American journal of clinical nutrition

Williams BA and McCartney H and Singer J and Devlin AM and Vercauteren S and Amid A and Wu JK and Crystal Karakochuk

DOI: 10.1016/j.ajcnut.2025.02.001 PubMed: 39921095

02 / 2025

Hemoglobin Barts hydrops fetalis: charting the past and envisioning the future

Blood

Ali Amid and Siyu Liu and Christian Babbs and Douglas R. Higgs

DOI: 10.1182/blood.2023023692

08 / 2024

Monolobated megakaryocytes in Diamond"Blackfan anemia with RPL5 mutation at disease presentation mimicking myelodysplastic syndrome

Pediatric Blood & Cancer

Audi Setiadi and Claudia Singh and Amanda Li and Nicholas Au and Ali Amid

DOI: 10.1002/pbc.30771

02 / 2024

Expanding the molecular and phenotypic spectrum of CTLA-4 insufficiency.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

Duke S and James Maiarana and Yousefi P and Burks E and Gerrie S and Audi Setiadi and BC Children's and St Paul's Hospital Members and Kyla J. Hildebrand and James E and Stuart E Turvey and Janet Markle and Catherine Biggs

DOI: 10.1111/pai.14077 PubMed: 38351878

02 / 2024

Rivaroxaban for Management of Venous Thromboembolism in Pediatric Nephrotic Syndrome; a Case Report and Review of Literature

Pediatric Hematology and Oncology

Marie-Claude Pelland-Marcotte and Soumitra Tole and Eve Bouhelier and Susan Lee and Jessica Halparin and Cherry Mammen and Karen Lyons and Ali Amid

DOI: 10.1080/08880018.2022.2150797

10 / 2023

Editorial: Modern approaches to hemophilia management in children and adolescents.

Frontiers in pediatrics

Amid A

DOI: 10.3389/fped.2023.1273639 PubMed: 37744446

09 / 2023

Moyamoya vasculopathy in hemoglobin H Constant Spring: Epidemiological coincidence or pathological consequence?

Pediatric Blood & Cancer

Rozalyn Chok and Jad El Maamari and Heather McCartney and Ali Amid

DOI: 10.1002/pbc.30236

06 / 2023

Between Scylla and Charybdis: thrombosis in children with hemophilia.

Frontiers in pediatrics

Jad El maamari and Amid A and Pelland-Marcotte MC and Tole S

DOI: 10.3389/fped.2023.1173549 PubMed: 37287631

05 / 2023

Optimizing transfusion therapy for survivors of Haemoglobin Bart's hydrops fetalis syndrome: Defining the targets for haemoglobin-H fraction and functional haemoglobin level

British Journal of Haematology

Ali Amid and Nick Barrowman and Isaac Odame and Melanie Kirby-Allen

DOI: 10.1111/bjh.18077

05 / 2022

Consensus statement for the perinatal management of patients with a thalassemia major

Blood Advances

Tippi C. MacKenzie and Ali Amid and Michael Angastiniotis and Craig Butler and Sandra Gilbert and Juan Gonzalez and Roberta L. Keller and Sandhya Kharbanda and Melanie Kirby-Allen and Barbara A. Koenig and Wade Kyono and Ashutosh Lal and Billie R. Lianoglou and Mary E. Norton and Keith K. Ogasawara and Tachjaree Panchalee and Mara Rosner and Marisa Schwab and Alexis Thompson and John S. Waye and Elliott Vichinsky

DOI: 10.1182/bloodadvances.2021005916

12 / 2021

Immune tolerance induction using Fc-fusion-protein recombinant factor IX in severe haemophilia B

Haemophilia

Ali Amid and Heather Perkins and Julie Gauthier and Arnaud Bonnefoy and Manuel Carcao and Georges-tienne Rivard and Robert J. Klaassen

DOI: 10.1111/hae.14424

11 / 2021

Outcomes of haemoglobin Barts hydrops fetalis following intrauterine transfusion in Ontario, Canada

Archives of Disease in Childhood - Fetal and Neonatal Edition

Hui Jue Zhang and Ali Amid and Laura A Janzen and Catherine I Segbefia and Shiyi Chen and Uma Athale and Karen Charpentier and Manuela Merelles-Pulcini and Gareth Seaward and Edmond N Kelly and Isaac Odame and John S Waye and Greg Ryan and Melanie Kirby-Allen

DOI: 10.1136/archdischild-2019-317626

01 / 2021

Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial.

The Lancet. Haematology

DOI: 10.1016/s2352-3026(20)30368-9 PubMed: 33290737

12 / 2020

Drisapersen associated with elevated serum factor VIII levels in Duchenne muscular dystrophy

Neurology

DOI: 10.1212/wnl.0000000000009139

03 / 2020

Safety of dabigatran etexilate for the secondary prevention of venous thromboembolism in children.

Blood

DOI: 10.1182/blood.2019000998 PubMed: 31805182

02 / 2020

Outcomes and risk factors of massive and submassive pulmonary embolism in children: a retrospective cohort study.

The Lancet. Haematology

DOI: 10.1016/s2352-3026(18)30224-2 PubMed: 30772417

02 / 2019

Mild Hereditary Spherocytosis without Accompanying Hereditary Haemochromatosis: An Unrecognised Cause of Iron Overload

Acta Haematologica

Soumitra Tole and Ali Amid and Jillian Baker and Kevin Kuo and Jakob Pugi and Manuel Carcao

DOI: 10.1159/000497175

Iron overload in transfusion-dependent survivors of hemoglobin Bart's hydrops fetalis.

Haematologica

DOI: 10.3324/haematol.2017.178368

01 / 2018

An international registry of survivors with Hb Bart's hydrops fetalis syndrome.

Blood

DOI: 10.1182/blood-2016-08-697110

03 / 2017

Optimizing chronic transfusion therapy for survivors of hemoglobin Barts hydrops fetalis

Blood

Ali Amid and Shiyi Chen and William Brien and Melanie Kirby-Allen and Isaac Odame

DOI: 10.1182/blood-2015-10-673889

03 / 2016

Hb S/+-thalassemia due to Hb sickle and a novel deletion of dnase I hypersensitive sites HS3 and HS4 of the locus control region

Haematologica

Amid, A. and Cheong, M. and Eng, B. and Hanna, M. and Hohenadel, B.-A. and Nakamura, L.M. and Walker, L. and Odame, I. and Kirby-Allen, M. and Waye, J.S.

DOI: 10.3324/haematol.2014.117408

Presentation of Central Nervous System Tumours

Pediatric Neuro-Oncology

Screening for thalassemia carriers in populations with a high rate of iron deficiency: Revisiting the applicability of the mentzer index and the effect of iron deficiency on Hb A2 levels

Hemoglobin

Amid, A. and Haghi-Ashtiani, B. and Kirby-Allen, M. and Haghi-Ashtiani, M.T.

DOI: 10.3109/03630269.2015.1024321

Thalassaemia in children: From quality of care to quality of life

Archives of Disease in Childhood

Amid, A. and Saliba, A.N. and Taher, A.T. and Klaassen, R.J.

DOI: 10.1136/archdischild-2014-308112

Improving outcomes in children with sickle cell disease: Treatment considerations and strategies

Pediatric Drugs

Amid, A. and Odame, I.

DOI: 10.1007/s40272-014-0074-4

Risk factors for hyperferritinemia secondary to red blood cell transfusions in pediatric cancer patients

Pediatric Blood and Cancer

Amid, A. and Barrowman, N. and Vijenthira, A. and Lesser, P. and Mandel, K. and Ramphal, R.

DOI: 10.1002/pbc.24629

Evans syndrome secondary to HIV infection

Journal of Pediatric Hematology/Oncology

Amid, A. and Leung, E.

DOI: 10.1097/MPH.0b013e3182a05a93

Impact of radiation avoidance on survival and neurocognitive outcome in infant medulloblastoma

Current Oncology

Lafay-Cousin, L. and Bouffet, E. and Hawkins, C. and Amid, A. and Huang, A. and Mabbott, D.J.

Thalassemia in Iran: Epidemiology, prevention, and management

Journal of Pediatric Hematology/Oncology

Abolghasemi, H. and Amid, A. and Zeinali, S. and Radfar, M.H. and Eshghi, P. and Rahiminejad, M.S. and Ehsani, M.A. and Najmabadi, H. and Akbari, M.T. and Afrasiabi, A. and Akhavan-Niaki, H. and Hoorfar, H.

DOI: 10.1097/MPH.0b013e3180437e02

International medical response to a natural disaster: Lessons learned from the bam earthquake experience

Prehospital and Disaster Medicine

Abolghasemi, H. and Radfar, M.H. and Khatami, M. and Nia, M.S. and Amid, A. and Briggs, S.M.

DOI: 10.1017/S1049023X00003599

Clinical quiz

Journal of Pediatric Gastroenterology and Nutrition

Abolghasemi, H. and Kavehmanesh, Z. and Matinzadeh, Z.K. and Amid, A. and Ahmadi, M.

Factor XIII deficiency in south-east Iran

Haemophilia

Eshghi, P. and Abolghasemi, H. and Sanei-Moghaddam, H. and Anwar, R. and Jazebi, M. and Amid, A. and Ala, F.A.

DOI: 10.1111/j.1365-2516.2004.00951.x

An update on the prevalence of glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice in Tehran neonates

Clinical Biochemistry

Abolghasemi, H. and Mehrani, H. and Amid, A.

DOI: 10.1016/j.clinbiochem.2003.11.010

Current Projects

Dr. Amid’s area of clinical and research interest is in the field of thalassemia, sickle cell disease, iron overload, and thrombosis, and he collaborates with other researchers on a national and international level. He is the principal investigator of an international collaborative research study in thalassemia (IntercontinenTHAL study), and a member of the Hemoglobin Bart’s Hydrops Fetalis Consortium and the International Pediatric Thrombosis Network. He has participated in numerous academic and registered clinical trials.

Honours & Awards

Dr. Amid has been the recipient of many research and clinical awards (e.g. Thalassemia Foundation of Canada Research Grant) and his research has been published in leading hematology journals like Blood, Lancet Haematology and Haematologica.

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