Andrew I.M. Campbell

Overview: I am a clinical researcher who specializes in research related to cardiac and thoracic surgery in children. I have a particular interest in blood vessel growth and development and how it can be altered using different strategies.
Publications: Can Isolated Discordant Atrioventricular Connections Survive Without Interatrial or Interventricular Shunt?
World Journal for Pediatric and Congenital Heart Surgery
Pranav Kandachar and Eapen Thomas and Areej Al Maskary and Andrew Campbell
DOI: 10.1177/21501351221145169
03/2023
On-Table Verification of Aortopulmonary Shunt Patency Through Ipsilateral Pulmonary Venous Blood Flow Assessment by Transesophageal Echocardiography
Journal of Cardiothoracic and Vascular Anesthesia
Madan Mohan Maddali and Amr Mohamed Abolwafa and Andrew Campbell
DOI: 10.1053/j.jvca.2020.08.006
07/2021
Tailoring the homing capacity of human Tregs for directed migration to sites of Th1-inflammation or intestinal regions
American Journal of Transplantation
DOI: 10.1111/ajt.14936
2019
Anticoagulation therapy and the risk of perioperative brain injury in neonates with congenital heart disease
Journal of Thoracic and Cardiovascular Surgery
DOI: 10.1016/j.jtcvs.2019.02.029
2019
The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease
Journal of Thoracic and Cardiovascular Surgery
DOI: 10.1016/j.jtcvs.2017.08.019
2018
Surgical and interventional management of adult congenital heart disease
British Columbia Medical Journal
2016
Association of prenatal diagnosis of critical congenital heart disease with postnatal brain development and the risk of brain injury
JAMA Pediatrics
DOI: 10.1001/jamapediatrics.2015.4450
2016
Discarded human thymus is a novel source of stable and long-lived therapeutic regulatory T cells
American Journal of Transplantation
DOI: 10.1111/ajt.13456
2016
False carina: a distinct variant of tracheal bronchus.
Rahmanian R and Zheng J and Chadha NK and Kozak FK and Campbell AI and Ludemann JP
DOI: 10.1016/j.ijporl.2015.01.023
PubMed: 25683591
04/2015
Cardiac strangulation following epicardial pacemaker implantation: a rare pediatric complication.
Carreras EM and Duncan WJ and Djurdjev O and Campbell AI
DOI: 10.1016/j.jtcvs.2014.10.094
PubMed: 25500288
02/2015
Casting a look at pediatric plastic bronchitis
International Journal of Pediatric Otorhinolaryngology
DOI: 10.1016/j.ijporl.2015.07.011
2015
Nonuniform and variable arrangements of ryanodine receptors within mammalian ventricular couplons.
Asghari P and Scriven DR and Sanatani S and Gandhi SK and Campbell AI and Moore ED
DOI: 10.1161/circresaha.115.303897
PubMed: 24786399
07/2014
Nonuniform and variable arrangements of ryanodine receptors within mammalian ventricular couplons
Circulation Research
DOI: 10.1161/CIRCRESAHA.115.303897
2014
Minimizing the risk of preoperative brain injury in neonates with aortic arch obstruction
Journal of Pediatrics
DOI: 10.1016/j.jpeds.2014.08.066
2014
Response to Comment on "helios⁺ and helios^- cells coexist within the natural FOXP31 T regulatory cell subset in humans"
Journal of Immunology
DOI: 10.4049/jimmunol.1390019
2013
Single-ventricle anatomy predicts delayed microstructural brain development
Pediatric Research
DOI: 10.1038/pr.2013.29
2013
Epidemiology of cardiac surgery-associated acute kidney injury in neonates: A retrospective study
Pediatric Nephrology
DOI: 10.1007/s00467-013-2454-3
2013
Brain injury and development in newborns with critical congenital heart disease
Neurology
DOI: 10.1212/WNL.0b013e31829bfdcf
2013
Modified slide tracheoplasty in a newborn with bronchial and carinal stenosis
International Journal of Pediatric Otorhinolaryngology
DOI: 10.1016/j.ijporl.2013.09.002
2013
Population-based review of tetralogy of Fallot with absent pulmonary valve: is prenatal diagnosis really associated with a poor prognosis?
Mivelaz Y and Lim KI and Templeton C and Campbell AI and Potts JE and Sandor GG
DOI: 10.1002/uog.11126
PubMed: 22302386
11/2012
The Contegra conduit: Late outcomes in right ventricular outflow tract reconstruction.
Holmes AA and Co S and Human DG and Leblanc JG and Campbell AI
DOI: 10.4103/0974-2069.93706
PubMed: 22529597
01/2012
Images in clinical medicine. Thrombosis of a mechanical mitral valve.
Harris KC and Campbell AI
DOI: 10.1056/nejmicm1100131
PubMed: 22168664
12/2011
Kingella kingae endocarditis: A rare case of mitral valve perforation.
Holmes AA and Hung T and Human DG and Campbell AI
DOI: 10.4103/0974-2069.84664
PubMed: 21976892
07/2011
Assessment of vocal fold mobility before and after cardiothoracic surgery in children.
Carpes LF and Kozak FK and Leblanc JG and Campbell AI and Human DG and Fandino M and Ludemann JP and Moxham JP and Fiori H
DOI: 10.1001/archoto.2011.84
PubMed: 21690509
06/2011
Infection and white matter injury in infants with congenital cardiac disease
Cardiology in the Young
DOI: 10.1017/S1047951111000473
2011
Thrombosis of a mechanical mitral valve
New England Journal of Medicine
DOI: 10.1056/NEJMicm1100131
2011
An unusual cause of anterior mediastinal mass.
Andrade JG and Leipsic JA and Campbell AI and Hung T and Kiess MC and Human DG
DOI: 10.1016/j.jacc.2009.11.104
PubMed: 20688217
08/2010
Safe retrieval of embolized patent ductus arteriosus coil via left thoracotomy
Experimental and Clinical Cardiology
2010
Clinically silent preoperative brain injuries do not worsen with surgery in neonates with congenital heart disease
Journal of Thoracic and Cardiovascular Surgery
DOI: 10.1016/j.jtcvs.2010.03.035
2010
Does biventricular pacing improve hemodynamics in children undergoing routine congenital heart surgery?
Pediatric Cardiology
DOI: 10.1007/s00246-009-9581-4
2010
Fear and loathing in Ottawa: The Royal college fellowship examination
Canadian Journal of Emergency Medicine
DOI: 10.1017/S1481803500011192
2009
Surgical repair of left internal jugular phlebectasia.
Hung T and Campbell AI
DOI: 10.1016/j.jvs.2007.12.040
PubMed: 18514849
06/2008
Serial blood lactate levels as a predictor of mortality in children after cardiopulmonary bypass surgery.
Kalyanaraman M and DeCampli WM and Campbell AI and Bhalala U and Harmon TG and Sandiford P and McMahon CK and Shore S and Yeh TS
DOI: 10.1097/pcc.0b013e31816c6f31
PubMed: 18446112
05/2008
Could we still improve early and interim outcome after prosthetic systemic-pulmonary shunt? A risk factors analysis
European Journal of Cardio-thoracic Surgery
DOI: 10.1016/j.ejcts.2008.06.001
2008
Serial blood lactate levels as a predictor of mortality in children after cardiopulmonary bypass surgery
Pediatric Critical Care Medicine
DOI: 10.1097/PCC.0b013e31816c6f31
2008
Left ventricular thrombosis following a Norwood procedure.
Duncan WJ and Campbell AI and Human DG
DOI: 10.1017/s1047951107000236
PubMed: 17580375
04/2007
Left ventricular thrombosis following a Norwood procedure
Cardiology in the Young
DOI: 10.1017/S1047951107000236
2007
Outcomes of pediatric patients bridged to heart transplantation from extracorporeal membrane oxygenation support
ASAIO Journal
DOI: 10.1097/01.mat.0000247153.41288.17
2007
Reciprocal regulation of angiopoietin-1 and angiopoietin-2 following myocardial infarction in the rat.
Sandhu R and Teichert-Kuliszewska K and Nag S and Proteau G and Robb MJ and Campbell AI and Kuliszewski MA and Kutryk MJ and Stewart DJ
DOI: 10.1016/j.cardiores.2004.05.013
PubMed: 15364619
10/2004
Protective role of angiopoietin-1 in experimental pulmonary hypertension.
Zhao YD and Campbell AI and Robb M and Ng D and Stewart DJ
DOI: 10.1161/01.res.0000070587.79937.f0
PubMed: 12690034
05/2003
Protective role of angiopoietin-1 in experimental pulmonary hypertension
Circulation Research
DOI: 10.1161/01.RES.0000070587.79937.F0
2003
Cell-based gene transfer of vascular endothelial growth factor attenuates monocrotaline-induced pulmonary hypertension.
Campbell AI and Zhao Y and Sandhu R and Stewart DJ
DOI: 10.1161/hc4201.097838
PubMed: 11684638
10/2001
Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2.
Teichert-Kuliszewska K and Maisonpierre PC and Jones N and Campbell AI and Master Z and Bendeck MP and Alitalo K and Dumont DJ and Yancopoulos GD and Stewart DJ
DOI: 10.1016/s0008-6363(00)00231-5
PubMed: 11166279
02/2001
Biological action of angiopoietin-2 in a fibrin matrix model of angiogenesis is associated with activation of Tie2
Cardiovascular Research
DOI: 10.1016/S0008-6363(00)00231-5
2001
Cell-based gene transfer to the pulmonary vasculature: Endothelial nitric oxide synthase overexpression inhibits monocrotaline-induced pulmonary hypertension.
Campbell AI and Kuliszewski MA and Stewart DJ
DOI: 10.1165/ajrcmb.21.5.3640
PubMed: 10536116
11/1999
Fluid dynamics of the CarboMedics kinetic bileaflet prosthetic heart valve
European Journal of Cardio-thoracic Surgery
DOI: 10.1016/S1010-7940(96)01034-2
1997
Pitfalls and outcomes from accelerated wear testing of mechanical heart valves
Journal of Heart Valve Disease
1996
Hydrodynamic function of tilting disc prostheses and bileaflet valves in double valve replacement
European Journal of Cardio-thoracic Surgery
DOI: 10.1016/S1010-7940(96)80109-6
1996
Hydrodynamic performance of carbomedics valves in double valve replacement
Journal of Heart Valve Disease
1994
Development of an ascending aortic valved conduit
Japanese Journal of Artificial Organs
1992
Research: Current Project
Angiogenic therapy for pulmonary hypertension (thesis with Institute of Medical Science at University of Toronto, Toronto, Ontario)

Honours & Awards

C. Walton Lillehei Award for outstanding research at the American Association of Thoracic Surgery - 1999
First Place, Poster Prize, Centre for Cardiovascular Research Scientific Day - 1999
First Prize, Gallie-Bateman Award for resident research in the Department of Surgery - 1999

Research Group Members

Susan Van Bruggen, Clinical Site Coordinator
Jane Wines, Lecturer

BC Children’s Hospital researchers bring Mini Med School to the Yukon for the first time

World-class researchers from BCCHR will travel to the Yukon on March 28 to present a day of discovery with Mini Med School. This health science youth outreach and public education program is designed for high school students to explore the world of health sciences, career opportunities in science and medicine, and connections with leading researchers and health experts.

Continue reading BC Children’s Hospital researchers bring Mini Med School to the Yukon for the first time

Torin Halvorson and Hebah Hussaina awarded Vanier scholarships for immunotherapy and mental health research

BC Children’s Hospital Research Institute (BCCHR) is proud to announce that two of its outstanding research trainees, Torin Halvorson, an MD/PhD student working with the Levings research team, and Hebah Hussaina, a graduate research assistant in the Brussoni Lab, have been awarded the prestigious 2024 Vanier Canada Graduate Scholarship.

Continue reading Torin Halvorson and Hebah Hussaina awarded Vanier scholarships for immunotherapy and mental health research

Studies highlight the impact of the pandemic on children and youth’s mental health

The Pediatric Outcome ImProvement through COordination of Research Networks — which involves BCCHR — has published their latest research findings on mental health hospitalizations of children and youth throughout the pandemic. These findings led the team to a second study where they evaluated the relationship between hospital admissions for eating disorders and public health restrictions.

Continue reading Studies highlight the impact of the pandemic on children and youth’s mental health

Recognizing a brain injury quickly can save lives

Knowing how to recognize brain injury as early as possible and what to do is crucial to reduce potential long-term complications. Mild traumatic brain injuries are more prevalent in children and youth than adults, often as a result of sport- and recreation-related events.

Continue reading Recognizing a brain injury quickly can save lives

A decade of work advances care for children with cancer

Researchers at the Michael Cuccione Childhood Cancer Research Program at BC Children’s Hospital Research Institute have been working for over a decade on the BC Pediatric Personalized OncoGenomics (PedsPOG) study, using genomics to identify treatments specific to an individual child’s cancer.

Continue reading A decade of work advances care for children with cancer

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